Mothur is a comprehensive suite of tools for microbial ecology community. It is initiated by Dr. Patrick Schloss and his software development team in the Department of Microbiology and Immunology at The University of Michigan. For more information, see Mothur-Wiki.
The homova command calculates the homogeneity of molecular variance (HOMOVA) from a phylip_distance_matrix, a nonparametric analog of Bartlett's test for homo- geneity of variance, which has been used in population genetics to test the hypothesis that the genetic diversity within two or more populations is homogeneous.
The Make_Design tool can construct a design file from a Mothur dataset that contains group names.
v.1.20.0: Updated to Mothur 1.33, added sets parameter