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Dr. Disco (classify) (version 0.14.0)

Output of Dr. Disco Detect:

only_valid:

Blacklist Regions:

List of regions known to be false positives (https://github.com/yhoogstrate/dr-disco/tree/master/share/)

Blacklist Junctions:

List of junctions know to be false positives (https://github.com/yhoogstrate/dr-disco/tree/master/share/)

Minimum alignment length on each side of the junction.:

May need to be set to smaller values for read lengths smaller than 75bp.

What it does

Step 3 in dr-disco pipeline

This tools filters the detected junctions which are likely to be true or false based on a variety of parameters provided in the input table. This filtering is in particular based on variables derived from the shape of the alignment and the ratio of split and spanning reads.

Attribution

This work is part of Youri Hoogstrate's PhD thesis.