Previous changeset 8:7a871df65202 (2020-07-28) |
Commit message:
"planemo upload for repository https://github.com/bgruening/galaxytools/tree/master/chemicaltoolbox/autodock_vina commit 8ae58ec16b3b6d62b47022745211f11181ad78ea" |
modified:
convert_pdbqt_to_sdf.py docking.xml test-data/ligand1_docked.sdf test-data/ligand2_docked.sdf test-data/ligand_docked.sdf test-data/ligand_params.sdf |
added:
test-data/ligand1_docked_flex.pdbqt test-data/ligand2_docked_flex.pdbqt test-data/ligand_docked_opt.sdf test-data/protein_flex.pdbqt test-data/protein_rigid.pdbqt |
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diff -r 7a871df65202 -r 90ea16534012 convert_pdbqt_to_sdf.py --- a/convert_pdbqt_to_sdf.py Tue Jul 28 08:13:41 2020 -0400 +++ b/convert_pdbqt_to_sdf.py Tue Dec 21 14:18:33 2021 +0000 |
[ |
@@ -1,40 +1,43 @@ import sys -from openbabel import pybel, openbabel +from openbabel import openbabel, pybel + def main(): - if len(sys.argv) == 3: - process(sys.argv[1], sys.argv[2]) - else: - print("Usage: convert_pdbqt_to_sdf.py <input-pdbqt-file> <output-sdf-file>") - exit(1) + if len(sys.argv) == 3: + process(sys.argv[1], sys.argv[2]) + else: + print("Usage: convert_pdbqt_to_sdf.py <input-pdbqt-file> <output-sdf-file>") + exit(1) + def add_property(mol, prop_name, prop_value): - newData = openbabel.OBPairData() - newData.SetAttribute(prop_name) - newData.SetValue(prop_value) - mol.OBMol.CloneData(newData) + newData = openbabel.OBPairData() + newData.SetAttribute(prop_name) + newData.SetValue(prop_value) + mol.OBMol.CloneData(newData) + def process(input, output): - docked = pybel.readfile('pdbqt', input) - sdf = pybel.Outputfile("sdf", output, overwrite=True) - for mol in docked: - if mol.OBMol.HasData('REMARK'): - remark = mol.OBMol.GetData('REMARK').GetValue() - lines = remark.splitlines() - tokens = lines[0].split() - - # add the score property - add_property(mol, "SCORE", tokens[2]) - # add the first RMSD property - add_property(mol, "RMSD_LB", tokens[3]) - # add the second RMSD property - add_property(mol, "RMSD_UB", tokens[4]) + docked = pybel.readfile("pdbqt", input) + sdf = pybel.Outputfile("sdf", output, overwrite=True) + for mol in docked: + if mol.OBMol.HasData("REMARK"): + remark = mol.OBMol.GetData("REMARK").GetValue() + lines = remark.splitlines() + tokens = lines[0].split() - sdf.write(mol) + # add the score property + add_property(mol, "SCORE", tokens[2]) + # add the first RMSD property + add_property(mol, "RMSD_LB", tokens[3]) + # add the second RMSD property + add_property(mol, "RMSD_UB", tokens[4]) - sdf.close() + sdf.write(mol) + + sdf.close() + if __name__ == "__main__": main() - |
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diff -r 7a871df65202 -r 90ea16534012 docking.xml --- a/docking.xml Tue Jul 28 08:13:41 2020 -0400 +++ b/docking.xml Tue Dec 21 14:18:33 2021 +0000 |
[ |
b'@@ -1,13 +1,14 @@\n <tool id="docking" name="VINA Docking" version="@TOOL_VERSION@+galaxy@GALAXY_VERSION@">\n+ <description>tool to perform protein-ligand docking with Autodock Vina</description>\n <macros>\n- <token name="@TOOL_VERSION@">1.1.2</token>\n+ <token name="@TOOL_VERSION@">1.2.3</token>\n <token name="@GALAXY_VERSION@">0</token>\n </macros>\n- <description>tool to perform protein-ligand docking with Autodock Vina</description>\n <requirements>\n- <requirement type="package" version="@TOOL_VERSION@">autodock-vina</requirement>\n+ <requirement type="package" version="@TOOL_VERSION@">vina</requirement>\n+ <requirement type="package" version="3.9">python</requirement>\n <requirement type="package" version="3.1.1">openbabel</requirement>\n- <requirement type="package" version="20200722">parallel</requirement>\n+ <requirement type="package" version="20211022">parallel</requirement>\n </requirements>\n <command detect_errors="exit_code"><![CDATA[\n #if $ligands.is_of_type("sdf")\n@@ -18,11 +19,14 @@\n mkdir output &&\n ls ligand*.pdbqt | parallel --will-cite -j \\${GALAXY_SLOTS:-1} $\'OUTNAME={.}_docked && vina\n --receptor \\\'$receptor\\\'\n+ #if $flex:\n+ --flex \\\'$flex\\\'\n+ #end if\n --ligand {}\n --out ./\\${OUTNAME}.pdbqt\n- --log ./\\${OUTNAME}.log\n --cpu 1\n- #if $config_params.config_params == \'vals\':\n+ --verbosity 2\n+ #if $config_params.config_params == "vals":\n --center_x $config_params.center_x\n --center_y $config_params.center_y\n --center_z $config_params.center_z\n@@ -32,23 +36,41 @@\n #if $config_params.exh != "":\n --exhaustiveness $config_params.exh\n #end if\n- #if $config_params.seed.seed == \'true\':\n+ #if $config_params.seed.seed == "true":\n --seed $config_params.seed.seed_value\n #end if\n- #else if $config_params.config_params == \'file\':\n+ #else if $config_params.config_params == "file":\n --config $config_params.box\n #if $config_params.exh != "":\n --exhaustiveness $config_params.exh\n #end if\n #end if\n- && python \\\'$__tool_directory__/convert_pdbqt_to_sdf.py\\\' ./\\${OUTNAME}.pdbqt output/\\${OUTNAME}.sdf\'\n- \n+ #if $settings.scoring:\n+ --scoring \\\'$settings.scoring\\\'\n+ #end if\n+ #if $settings.num_modes:\n+ --num_modes \\\'$settings.num_modes\\\'\n+ #end if\n+ #if $settings.min_rmsd:\n+ --min_rmsd \\\'$settings.min_rmsd\\\'\n+ #end if\n+ #if $settings.energy_range:\n+ --energy_range \\\'$settings.energy_range\\\'\n+ #end if\n+ #if $output == "sdf":\n+ && python \\\'$__tool_directory__/convert_pdbqt_to_sdf.py\\\' ./\\${OUTNAME}.pdbqt output/\\${OUTNAME}.sdf\n+ #end if\n+ \'\n+ #if $output == "pdbqt":\n+ && mv *docked.pdbqt output/\n+ #end if\n ]]></command>\n <inputs>\n- <param type="data" name="receptor" format="pdbqt" label="Receptor" help="Select a receptor (PDBQT format). This can be prepared using the receptor preparation tool." />\n+ <param type="data" name="receptor" format="pdbqt" label="Receptor" help="Select a receptor (PDBQT format). This can be prepared using the receptor preparation tool. If the \'Flexible side chains\' option is chosen, it should contain only the rigid part of the receptor." />\n <param type="data" name="ligands" format="sdf,pdbqt" label="Ligands" help="Select ligands (SDF format with multiple ligands or PDBQT format with single ligand)." />\n+ <param type="data" name="flex" format="pdbqt" optional="true" label="Flexible side chains" help="Part of the receptor which should be treated f'..b'tputs" type="list" label="Docked structures for ${on_string}" >\n+ <discover_datasets pattern="__name_and_ext__" directory="output" visible="false" />\n+ <filter>output == "pdbqt"</filter>\n </collection>\n </outputs>\n <tests>\n-\n <test>\n <param name="receptor" value="protein.pdbqt"/>\n <param name="ligands" value="input_ligands.sdf"/>\n <param name="box" value="box.txt"/>\n <output_collection name="sdf_outputs" type="list" count="5">\n- <element name="ligand1_docked" file="ligand1_docked.sdf" lines_diff="20"/>\n- <element name="ligand2_docked" file="ligand2_docked.sdf" lines_diff="20"/>\n+ <!-- linesdiff because there is a time stamp for each of the 9 poses -->\n+ <element name="ligand1_docked" file="ligand1_docked.sdf" lines_diff="18"/>\n+ <element name="ligand2_docked" file="ligand2_docked.sdf" lines_diff="18"/>\n <!-- we check only the first 2 -->\n </output_collection>\n </test>\n@@ -101,7 +143,21 @@\n <param name="ligands" value="input_ligand.pdbqt"/>\n <param name="box" value="box.txt"/>\n <output_collection name="sdf_outputs" type="list" count="1">\n- <element name="ligand1_docked" file="ligand_docked.sdf" lines_diff="1084"/>\n+ <element name="ligand1_docked" file="ligand_docked.sdf" lines_diff="18"/>\n+ </output_collection>\n+ </test>\n+\n+ <!-- test with optional params -->\n+ <test>\n+ <param name="receptor" value="protein.pdbqt"/>\n+ <param name="ligands" value="input_ligand.pdbqt"/>\n+ <param name="box" value="box.txt"/>\n+ <param name="scoring" value="vinardo"/>\n+ <param name="energy_range" value="5"/>\n+ <param name="num_modes" value="20"/>\n+ <param name="min_rmsd" value="0.5"/>\n+ <output_collection name="sdf_outputs" type="list" count="1">\n+ <element name="ligand1_docked" file="ligand_docked_opt.sdf" lines_diff="40"/>\n </output_collection>\n </test>\n \n@@ -121,10 +177,32 @@\n <param name="seed_value" value="8" />\n <param name="exh" value="10" />\n <output_collection name="sdf_outputs" type="list" count="1">\n- <element name="ligand1_docked" file="ligand_params.sdf" lines_diff="1084"/>\n+ <element name="ligand1_docked" file="ligand_params.sdf" lines_diff="18"/>\n </output_collection>\n </test>\n \n+ <!-- flexible docking -->\n+ <test>\n+ <param name="receptor" value="protein_rigid.pdbqt"/>\n+ <param name="flex" value="protein_flex.pdbqt"/>\n+ <param name="ligands" value="input_ligands.sdf"/>\n+ <param name="config_params" value="vals"/>\n+ <param name="center_x" value="15.2" />\n+ <param name="center_y" value="53.9" />\n+ <param name="center_z" value="16.9" />\n+ <param name="size_x" value="20" />\n+ <param name="size_y" value="20" />\n+ <param name="size_z" value="20" />\n+ <param name="seed" value="true" />\n+ <param name="seed_value" value="8" />\n+ <param name="exh" value="10" />\n+ <param name="output" value="pdbqt"/>\n+ <output_collection name="pdbqt_outputs" type="list" count="5">\n+ <element name="ligand1_docked" file="ligand1_docked_flex.pdbqt"/>\n+ <element name="ligand2_docked" file="ligand2_docked_flex.pdbqt"/>\n+ <!-- we check only the first 2 -->\n+ </output_collection>\n+ </test>\n </tests>\n <help><![CDATA[\n \n@@ -245,5 +323,6 @@\n ]]></help>\n <citations>\n <citation type="doi">10.1002/jcc.21334</citation>\n+ <citation type="doi">10.1021/acs.jcim.1c00203</citation>\n </citations>\n </tool>\n' |
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diff -r 7a871df65202 -r 90ea16534012 test-data/ligand1_docked.sdf --- a/test-data/ligand1_docked.sdf Tue Jul 28 08:13:41 2020 -0400 +++ b/test-data/ligand1_docked.sdf Tue Dec 21 14:18:33 2021 +0000 |
b |
b"@@ -1,39 +1,39 @@\n =\n- OpenBabel07272015563D\n+ OpenBabel11082113133D\n \n 18 19 0 0 1 0 0 0 0 0999 V2000\n- 34.9430 -44.6790 75.3760 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 34.9810 -45.3120 74.1360 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 33.8000 -45.4860 73.4300 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 32.5650 -45.0460 73.9280 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 32.5600 -44.4150 75.1790 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 33.7310 -44.2300 75.8970 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 31.3080 -45.2470 73.1490 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 30.1600 -44.5040 73.4380 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 28.9830 -44.6880 72.7230 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 28.9280 -45.6270 71.7060 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 30.0510 -46.3710 71.4040 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 31.2300 -46.1900 72.1180 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 36.0990 -44.4850 76.1000 O 0 0 0 0 0 0 0 0 0 0 0 0\n- 38.4420 -44.6700 76.3250 C 0 0 0 0 0 1 0 0 0 0 0 0\n- 37.3130 -44.2430 75.3990 C 0 0 2 0 0 3 0 0 0 0 0 0\n- 37.3440 -42.7630 75.0270 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 37.7170 -42.4800 73.8720 O 0 0 0 0 0 0 0 0 0 0 0 0\n- 36.9800 -41.9400 75.8900 O 0 0 0 0 0 1 0 0 0 0 0 0\n- 1 6 1 0 0 0 0\n+ 34.9500 -44.7140 75.3550 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 33.7160 -44.3540 75.8920 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 32.5660 -44.5710 75.1490 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 32.6060 -45.1410 73.8690 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 33.8610 -45.4910 73.3550 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 35.0220 -45.2840 74.0850 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 31.3530 -45.3630 73.0890 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 31.3280 -46.2560 72.0130 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 30.1690 -46.4650 71.2770 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 29.0090 -45.7780 71.5970 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 29.0120 -44.8930 72.6570 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 30.1710 -44.6810 73.3950 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 36.1110 -44.5170 76.0700 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 38.4560 -44.7090 76.2620 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 37.3170 -44.2630 75.3590 C 0 0 2 0 0 3 0 0 0 0 0 0\n+ 37.3470 -42.7770 75.0140 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 37.7110 -42.4720 73.8620 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 36.9910 -41.9700 75.8950 O 0 0 0 0 0 1 0 0 0 0 0 0\n+ 1 2 1 0 0 0 0\n 1 13 1 0 0 0 0\n- 2 1 2 0 0 0 0\n- 3 4 2 0 0 0 0\n- 3 2 1 0 0 0 0\n- 4 5 1 0 0 0 0\n- 5 6 2 0 0 0 0\n- 7 8 1 0 0 0 0\n+ 3 2 2 0 0 0 0\n+ 4 3 1 0 0 0 0\n+ 5 4 2 0 0 0 0\n+ 5 6 1 0 0 0 0\n+ 6 1 2 0 0 0 0\n+ 7 12 1 0 0 0 0\n 7 4 1 0 0 0 0\n- 9 8 2 0 0 0 0\n- 10 9 1 0 0 0 0\n- 11 10 2 0 0 0 0\n- 11 12 1 0 0 0 0\n- 12 7 2 0 0 0 0\n+ 8 7 2 0 0 0 0\n+ 9 10 2 0 0 0 0\n+ 9 8 1 0 0 0 0\n+ 10 11 1 0 0 0 0\n+ 11 12 2 0 0 0 0\n 15 13 1 0 0 0 0\n 15 14 1 1 0 0 0\n 16 15 1 0 0 0 0\n@@ -44,7 +44,11 @@\n 1\n \n > <REMARK>\n- VINA RESULT: -6.3 0.000 0.000\n+ VINA RESULT: -6.314 0.000 0.000\n+ INTER + INTRA: -8.427\n+ INTER: -7.803\n+ INTRA: -0.624\n+ UNBOUND: -0.636\n Name = \n 5 active torsions:\n status: ('A' for Active; 'I' for Inactive)\n@@ -60,7 +64,7 @@\n F 4\n \n > <SCORE>\n--6.3\n+-6.314\n \n > <RMSD_LB>\n 0.000\n@@ -70,34 +74,34 @@\n \n $$$$\n =\n- OpenBabel07272015563D\n+ OpenBabel11082113133D\n \n 18 19 0 0 1 0 0 0 0 0999 V2000\n- 32.0500 -45.3100 74.1090 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 32.9770 -45.9810 73.3150 C 0 0 0 0 0 3 0"..b" F 4\n \n > <SCORE>\n--5.1\n+-4.610\n \n > <RMSD_LB>\n-4.047\n+2.766\n \n > <RMSD_UB>\n-6.722\n+3.739\n \n $$$$\n =\n- OpenBabel07272015563D\n+ OpenBabel11082113133D\n \n 18 19 0 0 1 0 0 0 0 0999 V2000\n- 34.7830 -43.5140 77.4980 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 35.4850 -42.9340 78.5520 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 34.8800 -41.9340 79.2970 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 33.5800 -41.4840 79.0200 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 32.9010 -42.0860 77.9530 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 33.4900 -43.0900 77.1990 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 32.9520 -40.4040 79.8370 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 31.6620 -39.9490 79.5500 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 31.0700 -38.9400 80.3000 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 31.7620 -38.3580 81.3500 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 33.0380 -38.7940 81.6500 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 33.6320 -39.8030 80.9010 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 35.3540 -44.5150 76.7420 O 0 0 0 0 0 0 0 0 0 0 0 0\n- 35.8330 -45.5620 74.6810 C 0 0 0 0 0 1 0 0 0 0 0 0\n- 35.7350 -44.2270 75.4010 C 0 0 2 0 0 3 0 0 0 0 0 0\n- 37.0480 -43.4510 75.4500 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 37.0400 -42.2980 74.9780 O 0 0 0 0 0 0 0 0 0 0 0 0\n- 38.0320 -44.0110 75.9720 O 0 0 0 0 0 1 0 0 0 0 0 0\n- 1 2 1 0 0 0 0\n- 2 3 2 0 0 0 0\n- 4 3 1 0 0 0 0\n- 4 7 1 0 0 0 0\n- 5 4 2 0 0 0 0\n- 6 1 2 0 0 0 0\n- 6 5 1 0 0 0 0\n- 7 12 1 0 0 0 0\n+ 31.3630 -44.6700 73.1330 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 31.6520 -45.8770 72.5020 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 30.9320 -46.2380 71.3740 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 29.9170 -45.4260 70.8480 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 29.6500 -44.2180 71.5060 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 30.3620 -43.8390 72.6340 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 29.1570 -45.8380 69.6320 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 29.1900 -45.0630 68.4690 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 28.4800 -45.4350 67.3340 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 27.7140 -46.5890 67.3410 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 27.6690 -47.3700 68.4800 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 28.3770 -47.0000 69.6170 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 32.0640 -44.2780 74.2530 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 32.2260 -45.4420 76.3020 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 32.8600 -45.2420 74.9340 C 0 0 2 0 0 3 0 0 0 0 0 0\n+ 34.2880 -44.7070 74.9850 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 34.6160 -44.0700 76.0050 O 0 0 0 0 0 1 0 0 0 0 0 0\n+ 35.0350 -44.9550 74.0180 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 1 13 1 0 0 0 0\n+ 2 1 2 0 0 0 0\n+ 3 2 1 0 0 0 0\n+ 4 3 2 0 0 0 0\n+ 4 5 1 0 0 0 0\n+ 5 6 2 0 0 0 0\n+ 6 1 1 0 0 0 0\n+ 7 4 1 0 0 0 0\n 8 7 2 0 0 0 0\n- 8 9 1 0 0 0 0\n 9 10 2 0 0 0 0\n+ 9 8 1 0 0 0 0\n 10 11 1 0 0 0 0\n- 12 11 2 0 0 0 0\n- 13 1 1 0 0 0 0\n- 15 14 1 6 0 0 0\n+ 11 12 2 0 0 0 0\n+ 12 7 1 0 0 0 0\n+ 13 15 1 0 0 0 0\n 15 16 1 0 0 0 0\n- 15 13 1 0 0 0 0\n- 16 18 1 0 0 0 0\n- 17 16 2 0 0 0 0\n+ 15 14 1 1 0 0 0\n+ 16 17 1 0 0 0 0\n+ 18 16 2 0 0 0 0\n M END\n > <MODEL>\n 9\n \n > <REMARK>\n- VINA RESULT: -5.0 4.531 6.799\n+ VINA RESULT: -4.515 2.478 4.537\n+ INTER + INTRA: -6.207\n+ INTER: -5.570\n+ INTRA: -0.636\n+ UNBOUND: -0.636\n Name = \n 5 active torsions:\n status: ('A' for Active; 'I' for Inactive)\n@@ -628,12 +664,12 @@\n F 4\n \n > <SCORE>\n--5.0\n+-4.515\n \n > <RMSD_LB>\n-4.531\n+2.478\n \n > <RMSD_UB>\n-6.799\n+4.537\n \n $$$$\n" |
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diff -r 7a871df65202 -r 90ea16534012 test-data/ligand1_docked_flex.pdbqt --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/ligand1_docked_flex.pdbqt Tue Dec 21 14:18:33 2021 +0000 |
b |
b"@@ -0,0 +1,567 @@\n+MODEL 1\n+REMARK VINA RESULT: -9.488 0.000 0.000\n+REMARK INTER + INTRA: -13.271\n+REMARK INTER: -11.622\n+REMARK INTRA: -1.650\n+REMARK UNBOUND: -1.564\n+REMARK Name = \n+REMARK 5 active torsions:\n+REMARK status: ('A' for Active; 'I' for Inactive)\n+REMARK 1 A between atoms: C_1 and C_8\n+REMARK 2 A between atoms: C_2 and C_13\n+REMARK 3 A between atoms: C_8 and C_9\n+REMARK 4 A between atoms: C_8 and O_18\n+REMARK 5 A between atoms: C_10 and O_18\n+REMARK x y z vdW Elec q Type\n+REMARK _______ _______ _______ _____ _____ ______ ____\n+ROOT\n+ATOM 1 C UNL 1 16.180 56.319 12.922 0.00 0.00 +0.000 A \n+ATOM 2 C UNL 1 16.341 57.632 13.357 0.00 0.00 +0.000 A \n+ATOM 3 C UNL 1 15.267 58.505 13.283 0.00 0.00 +0.000 A \n+ATOM 4 C UNL 1 14.020 58.108 12.778 0.00 0.00 +0.000 A \n+ATOM 5 C UNL 1 13.890 56.782 12.347 0.00 0.00 +0.000 A \n+ATOM 6 C UNL 1 14.953 55.893 12.416 0.00 0.00 +0.000 A \n+ENDROOT\n+BRANCH 4 7\n+ATOM 7 C UNL 1 12.880 59.068 12.707 0.00 0.00 +0.000 A \n+ATOM 8 C UNL 1 11.894 58.937 11.725 0.00 0.00 +0.000 A \n+ATOM 9 C UNL 1 10.832 59.830 11.647 0.00 0.00 +0.000 A \n+ATOM 10 C UNL 1 10.738 60.879 12.547 0.00 0.00 +0.000 A \n+ATOM 11 C UNL 1 11.701 61.025 13.525 0.00 0.00 +0.000 A \n+ATOM 12 C UNL 1 12.765 60.134 13.606 0.00 0.00 +0.000 A \n+ENDBRANCH 4 7\n+BRANCH 1 13\n+ATOM 13 O UNL 1 17.226 55.424 12.988 0.00 0.00 +0.000 OA\n+BRANCH 13 15\n+ATOM 14 C UNL 1 17.571 53.682 14.543 0.00 0.00 +0.000 C \n+ATOM 15 C UNL 1 16.937 54.049 13.211 0.00 0.00 +0.000 C \n+BRANCH 15 16\n+ATOM 16 C UNL 1 17.488 53.263 12.025 0.00 0.00 +0.000 C \n+ATOM 17 O UNL 1 17.133 53.631 10.889 0.00 0.00 +0.000 OA\n+ATOM 18 O UNL 1 18.267 52.319 12.267 0.00 0.00 +0.000 OA\n+ENDBRANCH 15 16\n+ENDBRANCH 13 15\n+ENDBRANCH 1 13\n+TORSDOF 4\n+BEGIN_RES THR A 315\n+REMARK 2 active torsions:\n+REMARK status: ('A' for Active; 'I' for Inactive)\n+REMARK 1 A between atoms: CA and CB \n+REMARK 2 A between atoms: CB and OG1 \n+ROOT\n+ATOM 1 CA THR A 315 13.079 52.503 8.093 1.00 45.40 0.205 C \n+ENDROOT\n+BRANCH 1 2\n+ATOM 2 CB THR A 315 13.429 52.900 9.553 1.00 45.76 0.146 C \n+ATOM 3 CG2 THR A 315 13.686 51.713 10.412 1.00 42.73 0.042 C \n+BRANCH 2 4\n+ATOM 4 OG1 THR A 315 14.563 53.776 9.546 1.00 47.20 -0.393 OA\n+ATOM 5 HG1 THR A 315 14.634 54.137 8.791 1.00 47.20 0.210 HD\n+ENDBRANCH 2 4\n+ENDBRANCH 1 2\n+END_RES THR A 315\n+ENDMDL\n+MODEL 2\n+REMARK VINA RESULT: -8.686 3.038 6.782\n+REMARK INTER + INTRA: -12.281\n+REMARK INTER: -10.844\n+REMARK INTRA: -1.437\n+REMARK UNBOUND: -1.564\n+REMARK Name = \n+REMARK 5 active torsions:\n+REMARK status: ('A' for Active; 'I' for Inactive)\n+REMARK 1 A between atoms: C_1 and C_8\n+REMARK 2 A between atoms: C_2 and C_13\n+REMARK 3 A between atoms: C_8 and C_9\n+REMARK 4 A between atoms: C_8 and O_18\n+REMARK 5 A between atoms: C_10 and O_18\n+REMARK x y z vdW Elec q Type\n+REMARK _______ _______ _______ _____ _____ ______ ____\n+ROOT\n+ATOM 1 C UNL 1 13.712 58.842 13.234 0.00 0.00 +0.000 A \n+ATOM 2 C UNL 1 15.096 58.815 13.384 0.00 0.00 +0.000 A \n+ATOM 3 C UNL "..b" O UNL 1 14.306 50.202 16.969 0.00 0.00 +0.000 OA\n+ATOM 18 O UNL 1 12.724 48.715 16.532 0.00 0.00 +0.000 OA\n+ENDBRANCH 15 16\n+ENDBRANCH 13 15\n+ENDBRANCH 1 13\n+TORSDOF 4\n+BEGIN_RES THR A 315\n+REMARK 2 active torsions:\n+REMARK status: ('A' for Active; 'I' for Inactive)\n+REMARK 1 A between atoms: CA and CB \n+REMARK 2 A between atoms: CB and OG1 \n+ROOT\n+ATOM 1 CA THR A 315 13.079 52.503 8.093 1.00 45.40 0.205 C \n+ENDROOT\n+BRANCH 1 2\n+ATOM 2 CB THR A 315 13.429 52.900 9.553 1.00 45.76 0.146 C \n+ATOM 3 CG2 THR A 315 13.568 51.713 10.440 1.00 42.73 0.042 C \n+BRANCH 2 4\n+ATOM 4 OG1 THR A 315 14.631 53.679 9.556 1.00 47.20 -0.393 OA\n+ATOM 5 HG1 THR A 315 14.438 54.491 9.650 1.00 47.20 0.210 HD\n+ENDBRANCH 2 4\n+ENDBRANCH 1 2\n+END_RES THR A 315\n+ENDMDL\n+MODEL 9\n+REMARK VINA RESULT: -6.512 5.842 9.536\n+REMARK INTER + INTRA: -9.599\n+REMARK INTER: -8.034\n+REMARK INTRA: -1.564\n+REMARK UNBOUND: -1.564\n+REMARK Name = \n+REMARK 5 active torsions:\n+REMARK status: ('A' for Active; 'I' for Inactive)\n+REMARK 1 A between atoms: C_1 and C_8\n+REMARK 2 A between atoms: C_2 and C_13\n+REMARK 3 A between atoms: C_8 and C_9\n+REMARK 4 A between atoms: C_8 and O_18\n+REMARK 5 A between atoms: C_10 and O_18\n+REMARK x y z vdW Elec q Type\n+REMARK _______ _______ _______ _____ _____ ______ ____\n+ROOT\n+ATOM 1 C UNL 1 15.749 50.967 15.559 0.00 0.00 +0.000 A \n+ATOM 2 C UNL 1 14.383 50.812 15.783 0.00 0.00 +0.000 A \n+ATOM 3 C UNL 1 13.949 49.822 16.652 0.00 0.00 +0.000 A \n+ATOM 4 C UNL 1 14.843 48.966 17.310 0.00 0.00 +0.000 A \n+ATOM 5 C UNL 1 16.210 49.146 17.063 0.00 0.00 +0.000 A \n+ATOM 6 C UNL 1 16.663 50.133 16.201 0.00 0.00 +0.000 A \n+ENDROOT\n+BRANCH 4 7\n+ATOM 7 C UNL 1 14.350 47.908 18.239 0.00 0.00 +0.000 A \n+ATOM 8 C UNL 1 13.052 47.958 18.756 0.00 0.00 +0.000 A \n+ATOM 9 C UNL 1 12.584 46.981 19.627 0.00 0.00 +0.000 A \n+ATOM 10 C UNL 1 13.410 45.935 20.004 0.00 0.00 +0.000 A \n+ATOM 11 C UNL 1 14.695 45.866 19.504 0.00 0.00 +0.000 A \n+ATOM 12 C UNL 1 15.166 46.843 18.633 0.00 0.00 +0.000 A \n+ENDBRANCH 4 7\n+BRANCH 1 13\n+ATOM 13 O UNL 1 16.214 51.944 14.707 0.00 0.00 +0.000 OA\n+BRANCH 13 15\n+ATOM 14 C UNL 1 16.652 51.842 12.389 0.00 0.00 +0.000 C \n+ATOM 15 C UNL 1 15.585 52.104 13.441 0.00 0.00 +0.000 C \n+BRANCH 15 16\n+ATOM 16 C UNL 1 14.999 53.512 13.390 0.00 0.00 +0.000 C \n+ATOM 17 O UNL 1 15.424 54.269 12.497 0.00 0.00 +0.000 OA\n+ATOM 18 O UNL 1 14.125 53.806 14.230 0.00 0.00 +0.000 OA\n+ENDBRANCH 15 16\n+ENDBRANCH 13 15\n+ENDBRANCH 1 13\n+TORSDOF 4\n+BEGIN_RES THR A 315\n+REMARK 2 active torsions:\n+REMARK status: ('A' for Active; 'I' for Inactive)\n+REMARK 1 A between atoms: CA and CB \n+REMARK 2 A between atoms: CB and OG1 \n+ROOT\n+ATOM 1 CA THR A 315 13.079 52.503 8.093 1.00 45.40 0.205 C \n+ENDROOT\n+BRANCH 1 2\n+ATOM 2 CB THR A 315 13.429 52.900 9.553 1.00 45.76 0.146 C \n+ATOM 3 CG2 THR A 315 13.346 51.743 10.485 1.00 42.73 0.042 C \n+BRANCH 2 4\n+ATOM 4 OG1 THR A 315 14.737 53.484 9.584 1.00 47.20 -0.393 OA\n+ATOM 5 HG1 THR A 315 15.314 52.876 9.641 1.00 47.20 0.210 HD\n+ENDBRANCH 2 4\n+ENDBRANCH 1 2\n+END_RES THR A 315\n+ENDMDL\n" |
b |
diff -r 7a871df65202 -r 90ea16534012 test-data/ligand2_docked.sdf --- a/test-data/ligand2_docked.sdf Tue Jul 28 08:13:41 2020 -0400 +++ b/test-data/ligand2_docked.sdf Tue Dec 21 14:18:33 2021 +0000 |
b |
b"@@ -1,23 +1,23 @@\n =\n- OpenBabel07272015563D\n+ OpenBabel11082113133D\n \n 16 16 0 0 0 0 0 0 0 0999 V2000\n- 30.6630 -43.6920 75.9580 C 0 0 0 0 0 1 0 0 0 0 0 0\n- 34.9860 -42.7620 78.3530 C 0 0 0 0 0 1 0 0 0 0 0 0\n- 32.1620 -43.8570 76.0460 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 32.8840 -43.2860 77.0850 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 34.2670 -43.4120 77.1940 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 34.9330 -44.1500 76.2010 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 34.2380 -44.7360 75.1320 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 32.8570 -44.5700 75.0810 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 34.9310 -45.5200 74.0510 C 0 0 0 0 0 1 0 0 0 0 0 0\n- 37.2490 -43.5480 75.6000 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 36.3550 -44.3030 76.2650 N 0 0 0 0 0 0 0 0 0 0 0 0\n- 37.0120 -42.4630 75.0840 O 0 0 0 0 0 0 0 0 0 0 0 0\n- 36.7080 -45.0190 76.8410 H 0 0 0 0 0 0 0 0 0 0 0 0\n- 38.6290 -44.1290 75.4640 C 0 0 0 0 0 2 0 0 0 0 0 0\n- 38.5260 -46.2360 74.4260 C 0 0 0 0 0 1 0 0 0 0 0 0\n- 38.8100 -44.8480 74.2700 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 30.6810 -43.7000 75.9980 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 35.0390 -42.7570 78.3220 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 32.1820 -43.8610 76.0610 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 32.9190 -43.2870 77.0890 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 34.3040 -43.4090 77.1750 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 34.9560 -44.1440 76.1710 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 34.2460 -44.7330 75.1140 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 32.8630 -44.5710 75.0850 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 34.9240 -45.5140 74.0210 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 37.2610 -43.5180 75.5520 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 36.3800 -44.2920 76.2120 N 0 0 0 0 0 0 0 0 0 0 0 0\n+ 37.0130 -42.4230 75.0650 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 36.7440 -45.0200 76.7660 H 0 0 0 0 0 0 0 0 0 0 0 0\n+ 38.6420 -44.0900 75.3840 C 0 0 0 0 0 2 0 0 0 0 0 0\n+ 38.5370 -46.2430 74.4440 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 38.7820 -44.8570 74.2150 O 0 0 0 0 0 0 0 0 0 0 0 0\n 1 3 1 0 0 0 0\n 3 4 1 0 0 0 0\n 4 5 2 0 0 0 0\n@@ -39,7 +39,11 @@\n 1\n \n > <REMARK>\n- VINA RESULT: -4.9 0.000 0.000\n+ VINA RESULT: -4.845 0.000 0.000\n+ INTER + INTRA: -6.001\n+ INTER: -5.795\n+ INTRA: -0.206\n+ UNBOUND: -0.307\n Name = \n 7 active torsions:\n status: ('A' for Active; 'I' for Inactive)\n@@ -57,7 +61,7 @@\n F 3\n \n > <SCORE>\n--4.9\n+-4.845\n \n > <RMSD_LB>\n 0.000\n@@ -67,30 +71,30 @@\n \n $$$$\n =\n- OpenBabel07272015563D\n+ OpenBabel11082113133D\n \n 16 16 0 0 0 0 0 0 0 0999 V2000\n- 30.6380 -43.6200 76.0040 C 0 0 0 0 0 1 0 0 0 0 0 0\n- 34.8470 -45.5590 74.0520 C 0 0 0 0 0 1 0 0 0 0 0 0\n- 32.1370 -43.7980 76.0640 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 32.8070 -44.5440 75.1040 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 34.1860 -44.7340 75.1320 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 34.9040 -44.1390 76.1820 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 34.2610 -43.3840 77.1750 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 32.8790 -43.2340 77.0900 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 35.0070 -42.7480 78.3160 C 0 0 0 0 0 1 0 0 0 0 0 0\n- 37.2350 -43.5470 75.6290 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 36.3240 -44.3110 76.2590 N 0 0 0 0 0 0 0 0 0 0 0 0\n- 37.0170 -42.4440 75.1440 O 0 0 0 0 0 0 0 0 0 0 0 0\n- 36.6610 -45.0490 76.8180 H 0 0 0 0 0 0 0 0 0 0 0 0\n- 38.6100 -44.1400 75.4930 C 0 0 0 0 0 2 0 0 0 0 0 0\n- 38.5170 -"..b" 0\n+ 33.5730 -45.2500 74.0940 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 32.9550 -45.8380 73.0000 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 31.6110 -45.6330 72.6990 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 30.8750 -44.7940 73.5510 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 31.4660 -44.1760 74.6640 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 32.8150 -44.4210 74.9070 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 30.7000 -43.2640 75.5830 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 29.0120 -43.5220 72.5510 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 29.4900 -44.5460 73.2800 N 0 0 0 0 0 0 0 0 0 0 0 0\n+ 29.6720 -42.8320 71.7850 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 28.8350 -45.1760 73.6590 H 0 0 0 0 0 0 0 0 0 0 0 0\n+ 27.5550 -43.2010 72.7420 C 0 0 0 0 0 2 0 0 0 0 0 0\n+ 27.5770 -41.5680 74.4340 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 27.2280 -42.9030 74.0760 O 0 0 0 0 0 0 0 0 0 0 0 0\n 2 5 1 0 0 0 0\n 3 1 1 0 0 0 0\n 3 8 1 0 0 0 0\n@@ -580,10 +540,14 @@\n 16 15 1 0 0 0 0\n M END\n > <MODEL>\n-9\n+8\n \n > <REMARK>\n- VINA RESULT: -4.3 4.096 6.992\n+ VINA RESULT: -4.038 4.572 7.435\n+ INTER + INTRA: -5.052\n+ INTER: -4.719\n+ INTRA: -0.333\n+ UNBOUND: -0.307\n Name = \n 7 active torsions:\n status: ('A' for Active; 'I' for Inactive)\n@@ -601,12 +565,84 @@\n F 3\n \n > <SCORE>\n--4.3\n+-4.038\n \n > <RMSD_LB>\n-4.096\n+4.572\n \n > <RMSD_UB>\n-6.992\n+7.435\n \n $$$$\n+=\n+ OpenBabel11082113133D\n+\n+ 16 16 0 0 0 0 0 0 0 0999 V2000\n+ 34.4950 -43.2680 77.7490 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 33.8350 -46.0820 73.6330 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 33.5820 -43.7940 76.6650 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 34.0580 -44.6530 75.6840 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 33.2460 -45.1510 74.6680 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 31.9000 -44.7540 74.6570 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 31.3830 -43.8830 75.6280 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 32.2480 -43.4180 76.6160 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 29.9470 -43.4340 75.6300 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 30.7110 -44.5670 72.5030 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 31.0260 -45.2340 73.6280 N 0 0 0 0 0 0 0 0 0 0 0 0\n+ 31.3260 -43.6090 72.0540 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 30.6230 -46.1240 73.7550 H 0 0 0 0 0 0 0 0 0 0 0 0\n+ 29.4780 -45.0390 71.7820 C 0 0 0 0 0 2 0 0 0 0 0 0\n+ 27.4870 -44.0680 72.5720 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 28.3670 -45.1880 72.6300 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 2 5 1 0 0 0 0\n+ 3 1 1 0 0 0 0\n+ 4 3 2 0 0 0 0\n+ 5 4 1 0 0 0 0\n+ 6 5 2 0 0 0 0\n+ 6 7 1 0 0 0 0\n+ 7 9 1 0 0 0 0\n+ 7 8 2 0 0 0 0\n+ 8 3 1 0 0 0 0\n+ 10 11 1 0 0 0 0\n+ 11 13 1 0 0 0 0\n+ 11 6 1 0 0 0 0\n+ 12 10 2 0 0 0 0\n+ 14 10 1 0 0 0 0\n+ 14 16 1 0 0 0 0\n+ 15 16 1 0 0 0 0\n+M END\n+> <MODEL>\n+9\n+\n+> <REMARK>\n+ VINA RESULT: -3.825 3.905 6.318\n+ INTER + INTRA: -4.803\n+ INTER: -4.496\n+ INTRA: -0.307\n+ UNBOUND: -0.307\n+ Name = \n+ 7 active torsions:\n+ status: ('A' for Active; 'I' for Inactive)\n+ 1 A between atoms: C_1 and C_5\n+ 2 A between atoms: C_2 and C_12\n+ 3 A between atoms: C_2 and O_15\n+ 4 A between atoms: C_3 and O_15\n+ 5 A between atoms: C_4 and C_7\n+ 6 A between atoms: C_8 and N_13\n+ 7 A between atoms: C_9 and C_11\n+ x y z vdW Elec q Type\n+ _______ _______ _______ _____ _____ ______ ____\n+\n+> <TORSDO>\n+F 3\n+\n+> <SCORE>\n+-3.825\n+\n+> <RMSD_LB>\n+3.905\n+\n+> <RMSD_UB>\n+6.318\n+\n+$$$$\n" |
b |
diff -r 7a871df65202 -r 90ea16534012 test-data/ligand2_docked_flex.pdbqt --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/ligand2_docked_flex.pdbqt Tue Dec 21 14:18:33 2021 +0000 |
b |
b"@@ -0,0 +1,549 @@\n+MODEL 1\n+REMARK VINA RESULT: -7.600 0.000 0.000\n+REMARK INTER + INTRA: -10.239\n+REMARK INTER: -8.955\n+REMARK INTRA: -1.284\n+REMARK UNBOUND: -1.307\n+REMARK Name = \n+REMARK 7 active torsions:\n+REMARK status: ('A' for Active; 'I' for Inactive)\n+REMARK 1 A between atoms: C_1 and C_5\n+REMARK 2 A between atoms: C_2 and C_12\n+REMARK 3 A between atoms: C_2 and O_15\n+REMARK 4 A between atoms: C_3 and O_15\n+REMARK 5 A between atoms: C_4 and C_7\n+REMARK 6 A between atoms: C_8 and N_13\n+REMARK 7 A between atoms: C_9 and C_11\n+REMARK x y z vdW Elec q Type\n+REMARK _______ _______ _______ _____ _____ ______ ____\n+ROOT\n+ATOM 1 C UNL 1 12.578 60.281 13.517 0.00 0.00 +0.000 C \n+ATOM 2 C UNL 1 16.834 57.607 13.652 0.00 0.00 +0.000 C \n+ATOM 3 C UNL 1 13.320 59.001 13.210 0.00 0.00 +0.000 A \n+ATOM 4 C UNL 1 14.660 58.855 13.539 0.00 0.00 +0.000 A \n+ATOM 5 C UNL 1 15.377 57.693 13.265 0.00 0.00 +0.000 A \n+ATOM 6 C UNL 1 14.694 56.642 12.630 0.00 0.00 +0.000 A \n+ATOM 7 C UNL 1 13.340 56.755 12.276 0.00 0.00 +0.000 A \n+ATOM 8 C UNL 1 12.683 57.945 12.576 0.00 0.00 +0.000 A \n+ATOM 9 C UNL 1 12.592 55.648 11.585 0.00 0.00 +0.000 C \n+ENDROOT\n+BRANCH 6 11\n+ATOM 10 C UNL 1 15.391 54.319 13.082 0.00 0.00 +0.000 C \n+ATOM 11 N UNL 1 15.388 55.429 12.321 0.00 0.00 +0.000 N \n+ATOM 12 O UNL 1 14.594 54.076 13.979 0.00 0.00 +0.000 OA\n+ATOM 13 H UNL 1 15.906 55.404 11.484 0.00 0.00 +0.000 HD\n+BRANCH 10 14\n+ATOM 14 C UNL 1 16.496 53.337 12.809 0.00 0.00 +0.000 C \n+BRANCH 14 16\n+ATOM 15 C UNL 1 18.075 54.029 14.409 0.00 0.00 +0.000 C \n+ATOM 16 O UNL 1 17.777 53.875 13.023 0.00 0.00 +0.000 OA\n+ENDBRANCH 14 16\n+ENDBRANCH 10 14\n+ENDBRANCH 6 11\n+TORSDOF 3\n+BEGIN_RES THR A 315\n+REMARK 2 active torsions:\n+REMARK status: ('A' for Active; 'I' for Inactive)\n+REMARK 1 A between atoms: CA and CB \n+REMARK 2 A between atoms: CB and OG1 \n+ROOT\n+ATOM 1 CA THR A 315 13.079 52.503 8.093 1.00 45.40 0.205 C \n+ENDROOT\n+BRANCH 1 2\n+ATOM 2 CB THR A 315 13.429 52.900 9.553 1.00 45.76 0.146 C \n+ATOM 3 CG2 THR A 315 13.598 51.712 10.433 1.00 42.73 0.042 C \n+BRANCH 2 4\n+ATOM 4 OG1 THR A 315 14.615 53.704 9.553 1.00 47.20 -0.393 OA\n+ATOM 5 HG1 THR A 315 15.138 53.432 8.955 1.00 47.20 0.210 HD\n+ENDBRANCH 2 4\n+ENDBRANCH 1 2\n+END_RES THR A 315\n+ENDMDL\n+MODEL 2\n+REMARK VINA RESULT: -7.516 1.384 2.651\n+REMARK INTER + INTRA: -10.141\n+REMARK INTER: -9.075\n+REMARK INTRA: -1.066\n+REMARK UNBOUND: -1.307\n+REMARK Name = \n+REMARK 7 active torsions:\n+REMARK status: ('A' for Active; 'I' for Inactive)\n+REMARK 1 A between atoms: C_1 and C_5\n+REMARK 2 A between atoms: C_2 and C_12\n+REMARK 3 A between atoms: C_2 and O_15\n+REMARK 4 A between atoms: C_3 and O_15\n+REMARK 5 A between atoms: C_4 and C_7\n+REMARK 6 A between atoms: C_8 and N_13\n+REMARK 7 A between atoms: C_9 and C_11\n+REMARK x y z vdW Elec q Type\n+REMARK _______ _______ _______ _____ _____ ______ ____\n+ROOT\n+ATOM 1 C UNL 1 13.037 60.038 13.137 0.00 0.00 +0.000 C \n+ATOM 2 C UNL 1 13.429 55.125 12.138 0.00 0.00 +0.000 C \n+ATOM 3 C UNL "..b" 14 C UNL 1 14.976 45.924 21.245 0.00 0.00 +0.000 C \n+BRANCH 14 16\n+ATOM 15 C UNL 1 17.250 45.349 21.091 0.00 0.00 +0.000 C \n+ATOM 16 O UNL 1 15.921 45.061 20.664 0.00 0.00 +0.000 OA\n+ENDBRANCH 14 16\n+ENDBRANCH 10 14\n+ENDBRANCH 6 11\n+TORSDOF 3\n+BEGIN_RES THR A 315\n+REMARK 2 active torsions:\n+REMARK status: ('A' for Active; 'I' for Inactive)\n+REMARK 1 A between atoms: CA and CB \n+REMARK 2 A between atoms: CB and OG1 \n+ROOT\n+ATOM 1 CA THR A 315 13.079 52.503 8.093 1.00 45.40 0.205 C \n+ENDROOT\n+BRANCH 1 2\n+ATOM 2 CB THR A 315 13.429 52.900 9.553 1.00 45.76 0.146 C \n+ATOM 3 CG2 THR A 315 13.581 51.713 10.437 1.00 42.73 0.042 C \n+BRANCH 2 4\n+ATOM 4 OG1 THR A 315 14.624 53.690 9.555 1.00 47.20 -0.393 OA\n+ATOM 5 HG1 THR A 315 15.256 53.241 9.877 1.00 47.20 0.210 HD\n+ENDBRANCH 2 4\n+ENDBRANCH 1 2\n+END_RES THR A 315\n+ENDMDL\n+MODEL 9\n+REMARK VINA RESULT: -5.286 9.402 11.353\n+REMARK INTER + INTRA: -7.520\n+REMARK INTER: -6.213\n+REMARK INTRA: -1.307\n+REMARK UNBOUND: -1.307\n+REMARK Name = \n+REMARK 7 active torsions:\n+REMARK status: ('A' for Active; 'I' for Inactive)\n+REMARK 1 A between atoms: C_1 and C_5\n+REMARK 2 A between atoms: C_2 and C_12\n+REMARK 3 A between atoms: C_2 and O_15\n+REMARK 4 A between atoms: C_3 and O_15\n+REMARK 5 A between atoms: C_4 and C_7\n+REMARK 6 A between atoms: C_8 and N_13\n+REMARK 7 A between atoms: C_9 and C_11\n+REMARK x y z vdW Elec q Type\n+REMARK _______ _______ _______ _____ _____ ______ ____\n+ROOT\n+ATOM 1 C UNL 1 11.856 48.979 18.744 0.00 0.00 +0.000 C \n+ATOM 2 C UNL 1 13.773 45.019 21.179 0.00 0.00 +0.000 C \n+ATOM 3 C UNL 1 13.043 48.105 19.072 0.00 0.00 +0.000 A \n+ATOM 4 C UNL 1 12.915 47.013 19.920 0.00 0.00 +0.000 A \n+ATOM 5 C UNL 1 13.989 46.190 20.249 0.00 0.00 +0.000 A \n+ATOM 6 C UNL 1 15.239 46.498 19.689 0.00 0.00 +0.000 A \n+ATOM 7 C UNL 1 15.410 47.596 18.833 0.00 0.00 +0.000 A \n+ATOM 8 C UNL 1 14.297 48.381 18.546 0.00 0.00 +0.000 A \n+ATOM 9 C UNL 1 16.743 47.953 18.232 0.00 0.00 +0.000 C \n+ENDROOT\n+BRANCH 6 11\n+ATOM 10 C UNL 1 17.284 45.954 20.959 0.00 0.00 +0.000 C \n+ATOM 11 N UNL 1 16.377 45.685 20.002 0.00 0.00 +0.000 N \n+ATOM 12 O UNL 1 17.128 46.749 21.877 0.00 0.00 +0.000 OA\n+ATOM 13 H UNL 1 16.505 44.864 19.475 0.00 0.00 +0.000 HD\n+BRANCH 10 14\n+ATOM 14 C UNL 1 18.597 45.231 20.842 0.00 0.00 +0.000 C \n+BRANCH 14 16\n+ATOM 15 C UNL 1 19.944 46.262 19.214 0.00 0.00 +0.000 C \n+ATOM 16 O UNL 1 19.682 46.092 20.604 0.00 0.00 +0.000 OA\n+ENDBRANCH 14 16\n+ENDBRANCH 10 14\n+ENDBRANCH 6 11\n+TORSDOF 3\n+BEGIN_RES THR A 315\n+REMARK 2 active torsions:\n+REMARK status: ('A' for Active; 'I' for Inactive)\n+REMARK 1 A between atoms: CA and CB \n+REMARK 2 A between atoms: CB and OG1 \n+ROOT\n+ATOM 1 CA THR A 315 13.079 52.503 8.093 1.00 45.40 0.205 C \n+ENDROOT\n+BRANCH 1 2\n+ATOM 2 CB THR A 315 13.429 52.900 9.553 1.00 45.76 0.146 C \n+ATOM 3 CG2 THR A 315 13.553 51.714 10.443 1.00 42.73 0.042 C \n+BRANCH 2 4\n+ATOM 4 OG1 THR A 315 14.639 53.667 9.558 1.00 47.20 -0.393 OA\n+ATOM 5 HG1 THR A 315 15.256 53.219 9.205 1.00 47.20 0.210 HD\n+ENDBRANCH 2 4\n+ENDBRANCH 1 2\n+END_RES THR A 315\n+ENDMDL\n" |
b |
diff -r 7a871df65202 -r 90ea16534012 test-data/ligand_docked.sdf --- a/test-data/ligand_docked.sdf Tue Jul 28 08:13:41 2020 -0400 +++ b/test-data/ligand_docked.sdf Tue Dec 21 14:18:33 2021 +0000 |
b |
b"@@ -1,50 +1,54 @@\n =\n- OpenBabel07272015383D\n+ OpenBabel11082111323D\n \n 18 19 0 0 1 0 0 0 0 0999 V2000\n- 34.9430 -44.6790 75.3760 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 34.9810 -45.3120 74.1360 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 33.8000 -45.4860 73.4300 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 32.5650 -45.0460 73.9280 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 32.5600 -44.4150 75.1790 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 33.7310 -44.2300 75.8970 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 31.3080 -45.2470 73.1490 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 30.1600 -44.5040 73.4380 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 28.9830 -44.6880 72.7230 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 28.9280 -45.6270 71.7060 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 30.0510 -46.3710 71.4040 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 31.2300 -46.1900 72.1180 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 36.0990 -44.4850 76.1000 O 0 0 0 0 0 0 0 0 0 0 0 0\n- 38.4420 -44.6700 76.3250 C 0 0 0 0 0 1 0 0 0 0 0 0\n- 37.3130 -44.2430 75.3990 C 0 0 2 0 0 3 0 0 0 0 0 0\n- 37.3440 -42.7630 75.0270 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 37.7170 -42.4800 73.8720 O 0 0 0 0 0 0 0 0 0 0 0 0\n- 36.9800 -41.9400 75.8900 O 0 0 0 0 0 1 0 0 0 0 0 0\n- 1 6 1 0 0 0 0\n+ 35.0120 -44.7440 75.3480 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 33.7970 -44.3470 75.9050 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 32.6220 -44.5210 75.1900 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 32.6250 -45.0880 73.9090 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 33.8630 -45.4760 73.3770 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 35.0480 -45.3130 74.0770 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 31.3640 -45.2760 73.1350 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 31.2810 -46.1960 72.0840 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 30.0980 -46.3650 71.3740 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 28.9750 -45.6320 71.7000 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 29.0340 -44.7150 72.7360 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 30.2150 -44.5430 73.4480 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 36.1720 -44.5630 76.0690 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 38.5190 -44.7040 76.2810 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 37.3780 -44.2860 75.3660 C 0 0 2 0 0 3 0 0 0 0 0 0\n+ 37.3780 -42.8020 75.0140 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 37.0020 -41.9980 75.8910 O 0 0 0 0 0 1 0 0 0 0 0 0\n+ 37.7400 -42.4950 73.8620 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 1 2 1 0 0 0 0\n 1 13 1 0 0 0 0\n- 2 1 2 0 0 0 0\n- 3 4 2 0 0 0 0\n- 3 2 1 0 0 0 0\n- 4 5 1 0 0 0 0\n- 5 6 2 0 0 0 0\n- 7 8 1 0 0 0 0\n+ 3 2 2 0 0 0 0\n+ 4 3 1 0 0 0 0\n+ 5 4 2 0 0 0 0\n+ 5 6 1 0 0 0 0\n+ 6 1 2 0 0 0 0\n+ 7 12 1 0 0 0 0\n 7 4 1 0 0 0 0\n- 9 8 2 0 0 0 0\n- 10 9 1 0 0 0 0\n- 11 10 2 0 0 0 0\n- 11 12 1 0 0 0 0\n- 12 7 2 0 0 0 0\n+ 8 7 2 0 0 0 0\n+ 9 10 2 0 0 0 0\n+ 9 8 1 0 0 0 0\n+ 10 11 1 0 0 0 0\n+ 11 12 2 0 0 0 0\n 15 13 1 0 0 0 0\n 15 14 1 1 0 0 0\n 16 15 1 0 0 0 0\n- 16 18 1 0 0 0 0\n- 17 16 2 0 0 0 0\n+ 16 17 1 0 0 0 0\n+ 18 16 2 0 0 0 0\n M END\n > <MODEL>\n 1\n \n > <REMARK>\n- VINA RESULT: -6.3 0.000 0.000\n+ VINA RESULT: -6.339 0.000 0.000\n+ INTER + INTRA: -8.420\n+ INTER: -7.797\n+ INTRA: -0.623\n+ UNBOUND: -0.599\n Name = \n 5 active torsions:\n status: ('A' for Active; 'I' for Inactive)\n@@ -60,7 +64,7 @@\n F 4\n \n > <SCORE>\n--6.3\n+-6.339\n \n > <RMSD_LB>\n 0.000\n@@ -70,27 +74,27 @@\n \n $$$$\n =\n- OpenBabel07272015383D\n+ OpenBabel11082111323D\n \n 18 19 0 0 1 0 0 0 0 0999 V2000\n- 32.0500 -45.3100 74.1090 C"..b"RA: -0.616\n+ UNBOUND: -0.599\n Name = \n 5 active torsions:\n status: ('A' for Active; 'I' for Inactive)\n@@ -557,44 +589,44 @@\n F 4\n \n > <SCORE>\n--5.1\n+-5.021\n \n > <RMSD_LB>\n-4.047\n+4.808\n \n > <RMSD_UB>\n-6.722\n+7.215\n \n $$$$\n =\n- OpenBabel07272015383D\n+ OpenBabel11082111323D\n \n 18 19 0 0 1 0 0 0 0 0999 V2000\n- 34.7830 -43.5140 77.4980 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 35.4850 -42.9340 78.5520 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 34.8800 -41.9340 79.2970 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 33.5800 -41.4840 79.0200 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 32.9010 -42.0860 77.9530 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 33.4900 -43.0900 77.1990 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 32.9520 -40.4040 79.8370 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 31.6620 -39.9490 79.5500 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 31.0700 -38.9400 80.3000 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 31.7620 -38.3580 81.3500 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 33.0380 -38.7940 81.6500 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 33.6320 -39.8030 80.9010 C 0 0 0 0 0 3 0 0 0 0 0 0\n- 35.3540 -44.5150 76.7420 O 0 0 0 0 0 0 0 0 0 0 0 0\n- 35.8330 -45.5620 74.6810 C 0 0 0 0 0 1 0 0 0 0 0 0\n- 35.7350 -44.2270 75.4010 C 0 0 2 0 0 3 0 0 0 0 0 0\n- 37.0480 -43.4510 75.4500 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 37.0400 -42.2980 74.9780 O 0 0 0 0 0 0 0 0 0 0 0 0\n- 38.0320 -44.0110 75.9720 O 0 0 0 0 0 1 0 0 0 0 0 0\n- 1 2 1 0 0 0 0\n- 2 3 2 0 0 0 0\n- 4 3 1 0 0 0 0\n+ 35.9180 -43.7410 76.7410 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 36.4970 -42.4730 76.7170 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 35.9420 -41.4470 77.4660 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 34.8020 -41.6540 78.2530 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 34.2420 -42.9390 78.2540 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 34.7850 -43.9780 77.5140 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 34.1990 -40.5530 79.0600 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 32.9130 -40.0720 78.7940 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 32.3600 -39.0500 79.5580 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 33.0710 -38.4950 80.6040 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 34.3470 -38.9560 80.8840 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 34.9020 -39.9770 80.1220 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 36.4790 -44.7490 75.9880 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 35.2510 -45.5320 74.1300 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 36.4170 -44.6610 74.5700 C 0 0 2 0 0 3 0 0 0 0 0 0\n+ 37.7680 -45.1100 74.0190 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 38.2270 -46.1950 74.4260 O 0 0 0 0 0 1 0 0 0 0 0 0\n+ 38.3290 -44.3480 73.2080 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 1 6 1 0 0 0 0\n+ 2 1 2 0 0 0 0\n+ 2 3 1 0 0 0 0\n+ 3 4 2 0 0 0 0\n+ 4 5 1 0 0 0 0\n 4 7 1 0 0 0 0\n- 5 4 2 0 0 0 0\n- 6 1 2 0 0 0 0\n- 6 5 1 0 0 0 0\n+ 6 5 2 0 0 0 0\n 7 12 1 0 0 0 0\n 8 7 2 0 0 0 0\n 8 9 1 0 0 0 0\n@@ -603,16 +635,20 @@\n 12 11 2 0 0 0 0\n 13 1 1 0 0 0 0\n 15 14 1 6 0 0 0\n- 15 16 1 0 0 0 0\n 15 13 1 0 0 0 0\n- 16 18 1 0 0 0 0\n- 17 16 2 0 0 0 0\n+ 16 17 1 0 0 0 0\n+ 16 15 1 0 0 0 0\n+ 18 16 2 0 0 0 0\n M END\n > <MODEL>\n 9\n \n > <REMARK>\n- VINA RESULT: -5.0 4.531 6.799\n+ VINA RESULT: -4.647 4.120 6.702\n+ INTER + INTRA: -6.333\n+ INTER: -5.734\n+ INTRA: -0.599\n+ UNBOUND: -0.599\n Name = \n 5 active torsions:\n status: ('A' for Active; 'I' for Inactive)\n@@ -628,12 +664,12 @@\n F 4\n \n > <SCORE>\n--5.0\n+-4.647\n \n > <RMSD_LB>\n-4.531\n+4.120\n \n > <RMSD_UB>\n-6.799\n+6.702\n \n $$$$\n" |
b |
diff -r 7a871df65202 -r 90ea16534012 test-data/ligand_docked_opt.sdf --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/ligand_docked_opt.sdf Tue Dec 21 14:18:33 2021 +0000 |
b |
b"@@ -0,0 +1,1500 @@\n+=\n+ OpenBabel11082111333D\n+\n+ 18 19 0 0 1 0 0 0 0 0999 V2000\n+ 29.7070 -45.4080 71.9140 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 30.7920 -46.2730 71.7870 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 31.8970 -46.1200 72.6100 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 31.9510 -45.1050 73.5740 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 30.8450 -44.2500 73.6770 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 29.7300 -44.3900 72.8650 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 33.1380 -44.9330 74.4620 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 33.0100 -44.4490 75.7680 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 34.1240 -44.3000 76.5870 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 35.3810 -44.6360 76.1270 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 35.5320 -45.1170 74.8370 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 34.4210 -45.2670 74.0160 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 28.6170 -45.5710 71.0870 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 28.3460 -44.6160 68.9450 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 28.8390 -45.8360 69.7070 C 0 0 2 0 0 3 0 0 0 0 0 0\n+ 28.0990 -47.1240 69.3590 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 28.7480 -48.1880 69.3730 O 0 0 0 0 0 1 0 0 0 0 0 0\n+ 26.8920 -47.0200 69.0660 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 1 6 1 0 0 0 0\n+ 2 1 2 0 0 0 0\n+ 2 3 1 0 0 0 0\n+ 3 4 2 0 0 0 0\n+ 4 5 1 0 0 0 0\n+ 4 7 1 0 0 0 0\n+ 6 5 2 0 0 0 0\n+ 7 8 1 0 0 0 0\n+ 8 9 2 0 0 0 0\n+ 10 9 1 0 0 0 0\n+ 11 10 2 0 0 0 0\n+ 12 7 2 0 0 0 0\n+ 12 11 1 0 0 0 0\n+ 13 1 1 0 0 0 0\n+ 15 14 1 6 0 0 0\n+ 15 13 1 0 0 0 0\n+ 16 17 1 0 0 0 0\n+ 16 15 1 0 0 0 0\n+ 18 16 2 0 0 0 0\n+M END\n+> <MODEL>\n+1\n+\n+> <REMARK>\n+ VINA RESULT: -5.172 0.000 0.000\n+ INTER + INTRA: -7.229\n+ INTER: -6.351\n+ INTRA: -0.878\n+ UNBOUND: -0.847\n+ Name = \n+ 5 active torsions:\n+ status: ('A' for Active; 'I' for Inactive)\n+ 1 A between atoms: C_1 and C_8\n+ 2 A between atoms: C_2 and C_13\n+ 3 A between atoms: C_8 and C_9\n+ 4 A between atoms: C_8 and O_18\n+ 5 A between atoms: C_10 and O_18\n+ x y z vdW Elec q Type\n+ _______ _______ _______ _____ _____ ______ ____\n+\n+> <TORSDO>\n+F 4\n+\n+> <SCORE>\n+-5.172\n+\n+> <RMSD_LB>\n+0.000\n+\n+> <RMSD_UB>\n+0.000\n+\n+$$$$\n+=\n+ OpenBabel11082111333D\n+\n+ 18 19 0 0 1 0 0 0 0 0999 V2000\n+ 34.4560 -44.6880 75.2910 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 34.5320 -45.2460 74.0160 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 33.3780 -45.4020 73.2620 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 32.1270 -45.0120 73.7560 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 32.0840 -44.4560 75.0420 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 33.2260 -44.2890 75.8090 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 30.8820 -45.1790 72.9500 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 29.7300 -44.4350 73.2230 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 28.5780 -44.5960 72.4600 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 28.5540 -45.4920 71.4100 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 29.6840 -46.2400 71.1230 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 30.8360 -46.0820 71.8830 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 35.6100 -44.5410 76.0290 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 37.8880 -45.1540 75.9360 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 36.8230 -44.2400 75.3500 C 0 0 2 0 0 3 0 0 0 0 0 0\n+ 37.1060 -42.7530 75.5480 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 36.3280 -42.1070 76.2770 O 0 0 0 0 0 1 0 0 0 0 0 0\n+ 38.0930 -42.2820 74.9500 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 1 6 1 0 0 0 0\n+ 1 13 1 0 0 0 0\n+ 2 1 2 0 0 0 0\n+ 3 4 2 0 0 "..b"00 C 0 0 2 0 0 3 0 0 0 0 0 0\n+ 33.4720 -45.4080 73.7010 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 33.6380 -44.6110 72.7560 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 33.2270 -46.6240 73.5840 O 0 0 0 0 0 1 0 0 0 0 0 0\n+ 1 6 2 0 0 0 0\n+ 1 2 1 0 0 0 0\n+ 2 3 2 0 0 0 0\n+ 3 4 1 0 0 0 0\n+ 4 7 1 0 0 0 0\n+ 5 4 2 0 0 0 0\n+ 6 5 1 0 0 0 0\n+ 7 12 2 0 0 0 0\n+ 7 8 1 0 0 0 0\n+ 8 9 2 0 0 0 0\n+ 9 10 1 0 0 0 0\n+ 11 10 2 0 0 0 0\n+ 12 11 1 0 0 0 0\n+ 13 1 1 0 0 0 0\n+ 15 13 1 0 0 0 0\n+ 15 14 1 6 0 0 0\n+ 16 15 1 0 0 0 0\n+ 17 16 2 0 0 0 0\n+ 18 16 1 0 0 0 0\n+M END\n+> <MODEL>\n+19\n+\n+> <REMARK>\n+ VINA RESULT: -2.765 5.042 7.259\n+ INTER + INTRA: -4.259\n+ INTER: -3.348\n+ INTRA: -0.911\n+ UNBOUND: -0.847\n+ Name = \n+ 5 active torsions:\n+ status: ('A' for Active; 'I' for Inactive)\n+ 1 A between atoms: C_1 and C_8\n+ 2 A between atoms: C_2 and C_13\n+ 3 A between atoms: C_8 and C_9\n+ 4 A between atoms: C_8 and O_18\n+ 5 A between atoms: C_10 and O_18\n+ x y z vdW Elec q Type\n+ _______ _______ _______ _____ _____ ______ ____\n+\n+> <TORSDO>\n+F 4\n+\n+> <SCORE>\n+-2.765\n+\n+> <RMSD_LB>\n+5.042\n+\n+> <RMSD_UB>\n+7.259\n+\n+$$$$\n+=\n+ OpenBabel11082111333D\n+\n+ 18 19 0 0 1 0 0 0 0 0999 V2000\n+ 34.0630 -41.9770 69.7400 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 33.9830 -40.6090 69.4860 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 32.7420 -40.0050 69.3490 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 31.5560 -40.7420 69.4590 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 31.6710 -42.1170 69.7130 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 32.9020 -42.7380 69.8560 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 30.2190 -40.0980 69.3110 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 29.7620 -39.1430 70.2250 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 28.5160 -38.5460 70.0720 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 27.7060 -38.8800 69.0050 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 28.1380 -39.8240 68.0880 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 29.3830 -40.4220 68.2380 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 35.3020 -42.5650 69.8710 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 37.3140 -42.2930 68.6650 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 36.4610 -41.7420 69.7970 C 0 0 2 0 0 3 0 0 0 0 0 0\n+ 37.1430 -41.7800 71.1610 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 37.3290 -40.6950 71.7470 O 0 0 0 0 0 1 0 0 0 0 0 0\n+ 37.4840 -42.8990 71.5900 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 1 6 1 0 0 0 0\n+ 1 13 1 0 0 0 0\n+ 2 1 2 0 0 0 0\n+ 3 4 2 0 0 0 0\n+ 3 2 1 0 0 0 0\n+ 4 5 1 0 0 0 0\n+ 5 6 2 0 0 0 0\n+ 7 4 1 0 0 0 0\n+ 7 8 1 0 0 0 0\n+ 9 8 2 0 0 0 0\n+ 10 9 1 0 0 0 0\n+ 11 12 1 0 0 0 0\n+ 11 10 2 0 0 0 0\n+ 12 7 2 0 0 0 0\n+ 15 14 1 6 0 0 0\n+ 15 13 1 0 0 0 0\n+ 15 16 1 0 0 0 0\n+ 16 18 2 0 0 0 0\n+ 16 17 1 0 0 0 0\n+M END\n+> <MODEL>\n+20\n+\n+> <REMARK>\n+ VINA RESULT: -1.861 6.211 8.817\n+ INTER + INTRA: -3.144\n+ INTER: -2.296\n+ INTRA: -0.847\n+ UNBOUND: -0.847\n+ Name = \n+ 5 active torsions:\n+ status: ('A' for Active; 'I' for Inactive)\n+ 1 A between atoms: C_1 and C_8\n+ 2 A between atoms: C_2 and C_13\n+ 3 A between atoms: C_8 and C_9\n+ 4 A between atoms: C_8 and O_18\n+ 5 A between atoms: C_10 and O_18\n+ x y z vdW Elec q Type\n+ _______ _______ _______ _____ _____ ______ ____\n+\n+> <TORSDO>\n+F 4\n+\n+> <SCORE>\n+-1.861\n+\n+> <RMSD_LB>\n+6.211\n+\n+> <RMSD_UB>\n+8.817\n+\n+$$$$\n" |
b |
diff -r 7a871df65202 -r 90ea16534012 test-data/ligand_params.sdf --- a/test-data/ligand_params.sdf Tue Jul 28 08:13:41 2020 -0400 +++ b/test-data/ligand_params.sdf Tue Dec 21 14:18:33 2021 +0000 |
b |
b"@@ -1,25 +1,25 @@\n =\n- OpenBabel09251908563D\n+ OpenBabel11082111343D\n \n 18 19 0 0 1 0 0 0 0 0999 V2000\n- 34.9280 -44.6820 75.3750 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 33.7190 -44.2180 75.8910 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 32.5470 -44.4040 75.1740 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 32.5480 -45.0510 73.9310 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 33.7800 -45.5040 73.4390 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 34.9620 -45.3300 74.1420 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 31.2900 -45.2520 73.1550 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 30.1270 -44.5310 73.4460 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 28.9630 -44.7240 72.7110 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 28.9360 -45.6290 71.6680 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 30.0760 -46.3550 71.3620 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 31.2400 -46.1640 72.0960 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 36.0850 -44.4870 76.0970 O 0 0 0 0 0 0 0 0 0 0 0 0\n- 38.4290 -44.6740 76.3190 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 37.2990 -44.2490 75.3930 C 0 0 2 0 0 0 0 0 0 0 0 0\n- 37.3310 -42.7720 75.0140 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 37.7150 -42.4760 73.8650 O 0 0 0 0 0 0 0 0 0 0 0 0\n- 36.9860 -41.9560 75.8910 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 34.9490 -44.7080 75.3410 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 33.7180 -44.3220 75.8670 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 32.5580 -44.5340 75.1370 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 32.5940 -45.1310 73.8710 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 33.8490 -45.5070 73.3680 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 35.0180 -45.3060 74.0850 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 31.3510 -45.3610 73.0790 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 30.1650 -44.6760 73.3650 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 29.0150 -44.8950 72.6160 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 29.0230 -45.7920 71.5650 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 30.1860 -46.4820 71.2650 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 31.3380 -46.2650 72.0130 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 36.0930 -44.4880 76.0770 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 38.4340 -44.6680 76.3240 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 37.3140 -44.2430 75.3870 C 0 0 2 0 0 3 0 0 0 0 0 0\n+ 37.3460 -42.7640 75.0150 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 36.9770 -41.9410 75.8770 O 0 0 0 0 0 1 0 0 0 0 0 0\n+ 37.7250 -42.4800 73.8630 O 0 0 0 0 0 0 0 0 0 0 0 0\n 1 2 1 0 0 0 0\n 1 13 1 0 0 0 0\n 3 2 2 0 0 0 0\n@@ -37,14 +37,18 @@\n 15 13 1 0 0 0 0\n 15 14 1 1 0 0 0\n 16 15 1 0 0 0 0\n- 16 18 1 0 0 0 0\n- 17 16 2 0 0 0 0\n+ 16 17 1 0 0 0 0\n+ 18 16 2 0 0 0 0\n M END\n > <MODEL>\n 1\n \n > <REMARK>\n- VINA RESULT: -6.3 0.000 0.000\n+ VINA RESULT: -6.367 0.000 0.000\n+ INTER + INTRA: -8.455\n+ INTER: -7.819\n+ INTRA: -0.635\n+ UNBOUND: -0.599\n Name = \n 5 active torsions:\n status: ('A' for Active; 'I' for Inactive)\n@@ -60,7 +64,7 @@\n F 4\n \n > <SCORE>\n--6.3\n+-6.367\n \n > <RMSD_LB>\n 0.000\n@@ -70,34 +74,34 @@\n \n $$$$\n =\n- OpenBabel09251908563D\n+ OpenBabel11082111343D\n \n 18 19 0 0 1 0 0 0 0 0999 V2000\n- 31.9300 -45.2520 74.0180 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 32.3420 -44.4800 75.1030 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 33.6900 -44.4000 75.4200 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 34.6560 -45.0850 74.6710 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 34.2090 -45.8540 73.5870 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 32.8670 -45.9430 73.2530 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 36.1070 -45.0040 75.0080 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 36.9740 -46.0760 74.7690 C 0 0 0 "..b"0\n+-5.021\n \n > <RMSD_LB>\n-4.650\n+4.804\n \n > <RMSD_UB>\n-6.732\n+7.233\n \n $$$$\n =\n- OpenBabel09251908563D\n+ OpenBabel11082111343D\n \n 18 19 0 0 1 0 0 0 0 0999 V2000\n- 34.6100 -44.4120 75.7940 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 33.7490 -43.8540 76.7380 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 32.3970 -43.7370 76.4540 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 31.8700 -44.1680 75.2300 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 32.7610 -44.7240 74.3010 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 34.1160 -44.8510 74.5680 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 30.4160 -44.0440 74.9180 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 29.9370 -44.1560 73.6080 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 28.5790 -44.0440 73.3320 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 27.6730 -43.8270 74.3510 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 28.1250 -43.7120 75.6550 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 29.4820 -43.8230 75.9340 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 35.9510 -44.5190 76.0890 O 0 0 0 0 0 0 0 0 0 0 0 0\n- 37.8190 -45.6060 75.1370 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 36.8960 -44.4020 75.0310 C 0 0 2 0 0 0 0 0 0 0 0 0\n- 37.6070 -43.0610 75.1920 C 0 0 0 0 0 0 0 0 0 0 0 0\n- 36.9690 -42.1260 75.7140 O 0 0 0 0 0 0 0 0 0 0 0 0\n- 38.7780 -42.9890 74.7720 O 0 0 0 0 0 0 0 0 0 0 0 0\n- 1 13 1 0 0 0 0\n- 1 2 2 0 0 0 0\n- 3 2 1 0 0 0 0\n- 4 3 2 0 0 0 0\n- 5 6 2 0 0 0 0\n- 5 4 1 0 0 0 0\n- 6 1 1 0 0 0 0\n- 7 4 1 0 0 0 0\n- 7 12 2 0 0 0 0\n- 8 7 1 0 0 0 0\n- 9 8 2 0 0 0 0\n- 9 10 1 0 0 0 0\n- 10 11 2 0 0 0 0\n- 11 12 1 0 0 0 0\n- 15 14 1 1 0 0 0\n- 15 16 1 0 0 0 0\n+ 35.9180 -43.7410 76.7410 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 36.4970 -42.4730 76.7170 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 35.9420 -41.4470 77.4660 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 34.8020 -41.6540 78.2530 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 34.2420 -42.9390 78.2540 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 34.7850 -43.9780 77.5140 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 34.1990 -40.5530 79.0600 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 32.9130 -40.0720 78.7940 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 32.3600 -39.0500 79.5580 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 33.0710 -38.4950 80.6040 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 34.3470 -38.9560 80.8840 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 34.9020 -39.9770 80.1220 C 0 0 0 0 0 3 0 0 0 0 0 0\n+ 36.4790 -44.7490 75.9880 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 35.2510 -45.5320 74.1300 C 0 0 0 0 0 1 0 0 0 0 0 0\n+ 36.4170 -44.6610 74.5700 C 0 0 2 0 0 3 0 0 0 0 0 0\n+ 37.7680 -45.1100 74.0190 C 0 0 0 0 0 0 0 0 0 0 0 0\n+ 38.2270 -46.1950 74.4260 O 0 0 0 0 0 1 0 0 0 0 0 0\n+ 38.3290 -44.3480 73.2080 O 0 0 0 0 0 0 0 0 0 0 0 0\n+ 1 6 1 0 0 0 0\n+ 2 1 2 0 0 0 0\n+ 2 3 1 0 0 0 0\n+ 3 4 2 0 0 0 0\n+ 4 5 1 0 0 0 0\n+ 4 7 1 0 0 0 0\n+ 6 5 2 0 0 0 0\n+ 7 12 1 0 0 0 0\n+ 8 7 2 0 0 0 0\n+ 8 9 1 0 0 0 0\n+ 9 10 2 0 0 0 0\n+ 10 11 1 0 0 0 0\n+ 12 11 2 0 0 0 0\n+ 13 1 1 0 0 0 0\n+ 15 14 1 6 0 0 0\n 15 13 1 0 0 0 0\n 16 17 1 0 0 0 0\n+ 16 15 1 0 0 0 0\n 18 16 2 0 0 0 0\n M END\n > <MODEL>\n 9\n \n > <REMARK>\n- VINA RESULT: -4.9 1.456 2.281\n+ VINA RESULT: -4.647 4.130 6.780\n+ INTER + INTRA: -6.333\n+ INTER: -5.734\n+ INTRA: -0.599\n+ UNBOUND: -0.599\n Name = \n 5 active torsions:\n status: ('A' for Active; 'I' for Inactive)\n@@ -628,12 +664,12 @@\n F 4\n \n > <SCORE>\n--4.9\n+-4.647\n \n > <RMSD_LB>\n-1.456\n+4.130\n \n > <RMSD_UB>\n-2.281\n+6.780\n \n $$$$\n" |
b |
diff -r 7a871df65202 -r 90ea16534012 test-data/protein_flex.pdbqt --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/protein_flex.pdbqt Tue Dec 21 14:18:33 2021 +0000 |
b |
@@ -0,0 +1,17 @@ +BEGIN_RES THR A 315 +REMARK 2 active torsions: +REMARK status: ('A' for Active; 'I' for Inactive) +REMARK 1 A between atoms: CA and CB +REMARK 2 A between atoms: CB and OG1 +ROOT +ATOM 1 CA THR A 315 13.079 52.503 8.093 1.00 45.40 0.205 C +ENDROOT +BRANCH 1 2 +ATOM 2 CB THR A 315 13.429 52.900 9.553 1.00 45.76 0.146 C +ATOM 3 CG2 THR A 315 12.339 53.679 10.200 1.00 42.73 0.042 C +BRANCH 2 4 +ATOM 4 OG1 THR A 315 13.724 51.718 10.307 1.00 47.20 -0.393 OA +ATOM 5 HG1 THR A 315 13.915 51.930 11.097 1.00 47.20 0.210 HD +ENDBRANCH 2 4 +ENDBRANCH 1 2 +END_RES THR A 315 |
b |
diff -r 7a871df65202 -r 90ea16534012 test-data/protein_rigid.pdbqt --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/protein_rigid.pdbqt Tue Dec 21 14:18:33 2021 +0000 |
b |
b'@@ -0,0 +1,2582 @@\n+ATOM 1 N MET A 225 19.489 41.513 -4.249 1.00 79.27 0.615 N \n+ATOM 2 CA MET A 225 20.312 40.392 -4.798 1.00 78.95 0.400 C \n+ATOM 3 C MET A 225 19.479 39.195 -5.296 1.00 77.61 0.257 C \n+ATOM 4 O MET A 225 18.259 39.153 -5.110 1.00 77.57 -0.271 OA\n+ATOM 5 CB MET A 225 21.339 39.952 -3.749 1.00 79.64 0.061 C \n+ATOM 6 CG MET A 225 20.774 39.716 -2.360 1.00 80.22 0.076 C \n+ATOM 7 SD MET A 225 22.046 39.929 -1.082 1.00 82.21 -0.173 SA\n+ATOM 8 CE MET A 225 23.071 38.466 -1.342 1.00 80.61 0.089 C \n+ATOM 9 N ASP A 226 20.150 38.233 -5.930 1.00 76.04 -0.345 N \n+ATOM 10 CA ASP A 226 19.492 37.056 -6.502 1.00 74.10 0.188 C \n+ATOM 11 C ASP A 226 19.223 35.910 -5.528 1.00 73.63 0.244 C \n+ATOM 12 O ASP A 226 20.111 35.490 -4.776 1.00 71.73 -0.271 OA\n+ATOM 13 CB ASP A 226 20.303 36.543 -7.684 1.00 74.44 0.024 C \n+ATOM 14 H ASP A 226 21.003 38.244 -6.041 1.00 76.04 0.163 HD\n+ATOM 15 N PRO A 227 17.986 35.376 -5.547 1.00 73.27 -0.337 N \n+ATOM 16 CA PRO A 227 17.583 34.273 -4.671 1.00 73.15 0.179 C \n+ATOM 17 C PRO A 227 18.503 33.087 -4.870 1.00 74.73 0.241 C \n+ATOM 18 O PRO A 227 18.546 32.174 -4.049 1.00 74.21 -0.271 OA\n+ATOM 19 CB PRO A 227 16.140 33.999 -5.090 1.00 72.37 0.037 C \n+ATOM 20 CG PRO A 227 16.101 34.445 -6.515 1.00 73.04 0.022 C \n+ATOM 21 CD PRO A 227 16.911 35.708 -6.501 1.00 73.01 0.127 C \n+ATOM 22 N SER A 228 19.240 33.123 -5.977 1.00 76.73 -0.344 N \n+ATOM 23 CA SER A 228 20.217 32.091 -6.313 1.00 78.88 0.200 C \n+ATOM 24 C SER A 228 21.561 32.619 -5.816 1.00 79.37 0.243 C \n+ATOM 25 O SER A 228 22.241 33.368 -6.526 1.00 80.10 -0.271 OA\n+ATOM 26 CB SER A 228 20.296 31.881 -7.832 1.00 79.04 0.199 C \n+ATOM 27 OG SER A 228 19.032 31.572 -8.391 1.00 79.63 -0.398 OA\n+ATOM 28 H SER A 228 19.186 33.753 -6.560 1.00 76.73 0.163 HD\n+ATOM 29 HG SER A 228 19.111 31.465 -9.220 1.00 79.63 0.209 HD\n+ATOM 30 N SER A 229 21.926 32.245 -4.593 1.00 78.77 -0.345 N \n+ATOM 31 CA SER A 229 23.185 32.678 -3.993 1.00 79.14 0.189 C \n+ATOM 32 C SER A 229 23.161 32.400 -2.501 1.00 78.94 0.263 C \n+ATOM 33 O SER A 229 22.119 32.522 -1.853 1.00 79.27 -0.269 OA\n+ATOM 34 CB SER A 229 23.414 34.172 -4.234 1.00 78.50 0.024 C \n+ATOM 35 H SER A 229 21.452 31.734 -4.089 1.00 78.77 0.163 HD\n+ATOM 36 N PRO A 230 24.310 32.018 -1.960 1.00 78.55 -0.239 NA\n+ATOM 37 CA PRO A 230 24.408 31.738 -0.537 1.00 77.41 0.214 C \n+ATOM 38 C PRO A 230 24.177 33.042 0.217 1.00 76.20 0.244 C \n+ATOM 39 O PRO A 230 24.598 34.117 -0.228 1.00 76.01 -0.271 OA\n+ATOM 40 CB PRO A 230 25.790 31.164 -0.200 1.00 77.54 0.026 C \n+ATOM 41 N ASN A 231 23.491 32.939 1.350 1.00 74.65 -0.345 N \n+ATOM 42 CA ASN A 231 23.201 34.098 2.186 1.00 72.64 0.188 C \n+ATOM 43 C ASN A 231 22.336 35.144 1.484 1.00 71.14 0.242 C \n+ATOM 44 O ASN A 231 22.503 36.345 1.714 1.00 70.95 -0.271 OA\n+ATOM 45 CB ASN A 231 24.507 34.738 2.660 1.00 73.26 0.024 C \n+ATOM 46 H ASN A 231 23.181 32.197 1.655 1.00 74.65 0.163 HD\n+ATOM 47 N TYR A 232 21.428 34.702 0.613 1.00 67.45 -0.346 N \n+ATOM 48 CA TYR A 232 20.550 35.654 -0.051 1.00 63.27 0.180 C \n+ATOM 49 C TYR A 232 19.883 36.358 1.112 1.00 61.88 0.241 C \n+ATOM 5'..b'.511 1.00 76.12 0.172 C \n+ATOM 2534 OE1 GLU A 494 -6.575 44.192 25.282 1.00 78.16 -0.648 OA\n+ATOM 2535 OE2 GLU A 494 -6.525 45.077 23.265 1.00 77.38 -0.648 OA\n+ATOM 2536 H GLU A 494 -5.879 47.855 27.686 1.00 61.95 0.163 HD\n+ATOM 2537 N THR A 495 -8.985 47.736 28.526 1.00 66.37 -0.344 N \n+ATOM 2538 CA THR A 495 -10.185 47.843 29.336 1.00 67.39 0.205 C \n+ATOM 2539 C THR A 495 -10.471 49.316 29.595 1.00 69.26 0.243 C \n+ATOM 2540 O THR A 495 -11.540 49.840 29.273 1.00 68.79 -0.271 OA\n+ATOM 2541 CB THR A 495 -10.001 47.138 30.692 1.00 67.11 0.146 C \n+ATOM 2542 OG1 THR A 495 -9.877 45.726 30.487 1.00 64.92 -0.393 OA\n+ATOM 2543 CG2 THR A 495 -11.185 47.424 31.605 1.00 67.21 0.042 C \n+ATOM 2544 H THR A 495 -8.397 47.186 28.828 1.00 66.37 0.163 HD\n+ATOM 2545 HG1 THR A 495 -9.090 45.544 30.255 1.00 64.92 0.210 HD\n+ATOM 2546 N MET A 496 -9.486 49.975 30.183 1.00 70.48 -0.346 N \n+ATOM 2547 CA MET A 496 -9.584 51.377 30.515 1.00 72.06 0.177 C \n+ATOM 2548 C MET A 496 -9.918 52.191 29.269 1.00 73.93 0.241 C \n+ATOM 2549 O MET A 496 -10.586 53.224 29.347 1.00 74.19 -0.271 OA\n+ATOM 2550 CB MET A 496 -8.254 51.814 31.119 1.00 70.74 0.045 C \n+ATOM 2551 CG MET A 496 -8.268 53.128 31.840 1.00 69.50 0.076 C \n+ATOM 2552 SD MET A 496 -6.954 53.109 33.054 1.00 70.45 -0.173 SA\n+ATOM 2553 CE MET A 496 -5.542 52.993 32.023 1.00 71.50 0.089 C \n+ATOM 2554 H MET A 496 -8.736 49.615 30.401 1.00 70.48 0.163 HD\n+ATOM 2555 N PHE A 497 -9.469 51.711 28.113 1.00 76.39 -0.346 N \n+ATOM 2556 CA PHE A 497 -9.728 52.421 26.867 1.00 78.51 0.180 C \n+ATOM 2557 C PHE A 497 -11.222 52.482 26.591 1.00 80.00 0.241 C \n+ATOM 2558 O PHE A 497 -11.656 53.107 25.627 1.00 80.73 -0.271 OA\n+ATOM 2559 CB PHE A 497 -8.992 51.764 25.694 1.00 77.30 0.073 C \n+ATOM 2560 CG PHE A 497 -8.889 52.645 24.483 1.00 75.26 -0.056 A \n+ATOM 2561 CD1 PHE A 497 -8.326 53.910 24.587 1.00 73.03 0.007 A \n+ATOM 2562 CD2 PHE A 497 -9.374 52.223 23.248 1.00 75.22 0.007 A \n+ATOM 2563 CE1 PHE A 497 -8.251 54.749 23.481 1.00 73.27 0.001 A \n+ATOM 2564 CE2 PHE A 497 -9.304 53.054 22.132 1.00 75.21 0.001 A \n+ATOM 2565 CZ PHE A 497 -8.740 54.323 22.248 1.00 74.83 0.000 A \n+ATOM 2566 H PHE A 497 -9.017 50.984 28.029 1.00 76.39 0.163 HD\n+ATOM 2567 N GLN A 498 -12.005 51.821 27.440 1.00 82.65 -0.345 N \n+ATOM 2568 CA GLN A 498 -13.459 51.848 27.319 1.00 83.69 0.188 C \n+ATOM 2569 C GLN A 498 -13.830 53.253 27.778 1.00 84.42 0.242 C \n+ATOM 2570 O GLN A 498 -13.228 53.773 28.721 1.00 84.42 -0.271 OA\n+ATOM 2571 CB GLN A 498 -14.091 50.807 28.237 1.00 83.83 0.024 C \n+ATOM 2572 H GLN A 498 -11.711 51.349 28.096 1.00 82.65 0.163 HD\n+ATOM 2573 N GLU A 499 -14.808 53.869 27.123 1.00 85.39 -0.347 N \n+ATOM 2574 CA GLU A 499 -15.206 55.233 27.465 1.00 85.86 0.163 C \n+ATOM 2575 C GLU A 499 -14.088 56.187 27.012 1.00 85.54 0.219 C \n+ATOM 2576 O GLU A 499 -13.405 56.771 27.885 1.00 85.21 -0.287 OA\n+ATOM 2577 CB GLU A 499 -15.435 55.382 28.980 1.00 86.36 0.044 C \n+ATOM 2578 CG GLU A 499 -16.854 55.784 29.370 1.00 87.39 0.116 C \n+ATOM 2579 CD GLU A 499 -17.743 54.590 29.672 1.00 88.29 0.172 C \n+ATOM 2580 OE1 GLU A 499 -17.551 53.964 30.738 1.00 89.34 -0.648 OA\n+ATOM 2581 OE2 GLU A 499 -18.627 54.272 28.849 1.00 87.77 -0.648 OA\n+ATOM 2582 H GLU A 499 -15.254 53.517 26.478 1.00 85.39 0.163 HD\n' |