Repository 'hmmer_nhmmscan'
hg clone https://toolshed.g2.bx.psu.edu/repos/iuc/hmmer_nhmmscan

Changeset 0:a6098dd0cb46 (2016-06-25)
Next changeset 1:4351ee79c942 (2016-11-14)
Commit message:
planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit 4261b86af790a3535c0b9a8122f92225f8f67b47
added:
TODO.md
macros.xml
nhmmscan.xml
readme.rst
test-data/MADE1.hmm
test-data/MADE1.out
test-data/MADE1.out.domtblout
test-data/MADE1.out.pfamtblout
test-data/MADE1.out.tblout
test-data/MADE1.sto
test-data/dna_target.fa
test-data/fn3.hmm
test-data/fn3.keys
test-data/fn3.out
test-data/fn3.sto
test-data/globins-45-align.sto
test-data/globins-masked.sto
test-data/globins.domtblout
test-data/globins.pfamtblout
test-data/globins.tblout
test-data/globins4-emit-1.sto
test-data/globins4-emit.sto
test-data/globins4.hmm
test-data/globins4.hmm.bin
test-data/globins4.hmm2
test-data/globins4.out
test-data/globins4.sto
test-data/globins45.fa
test-data/jackhmmer.domtblout
test-data/jackhmmer.out
test-data/jackhmmer.tblout
test-data/nhmmer.out
test-data/phmmer.domtblout
test-data/phmmer.out
test-data/phmmer.pfamtblout
test-data/phmmer.tblout
test-data/uniprot_globins_match.out
test-data/uniprot_matches.fasta
tool_dependencies.xml
b
diff -r 000000000000 -r a6098dd0cb46 TODO.md
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/TODO.md Sat Jun 25 15:07:32 2016 -0400
b
@@ -0,0 +1,39 @@
+# Necessary
+
+- output names on `$(grep tblout *.xml)`
+- Help text
+- HmmPress datatypes
+- Publicly available hmm databases? data manager needed? Locally installed, etc?
+- Use hmmpress databases in History/Locally Cached/etc
+
+# Programs
+
+- hmmstat
+- hmmsim
+- hmmc2
+- hmmlogo +skylign
+
+Easel toolkit
+
+- esl-afetch
+- esl-alimanip
+- esl-alimap
+- esl-alimask
+- esl-alimerge
+- esl-alipid
+- esl-alistat
+- esl-cluster
+- esl-compalign
+- esl-compstruct
+- esl-construct
+- esl-histplot
+- esl-mask
+- esl-reformat
+- esl-selectn
+- esl-seqrange
+- esl-seqstat
+- esl-sfetch
+- esl-shuffle
+- esl-ssdraw
+- esl-stranslate
+- esl-weight
b
diff -r 000000000000 -r a6098dd0cb46 macros.xml
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/macros.xml Sat Jun 25 15:07:32 2016 -0400
[
b'@@ -0,0 +1,1072 @@\n+<?xml version="1.0"?>\n+<macros>\n+  <xml name="requirements">\n+    <requirements>\n+      <requirement type="package" version="3.1b2">hmmer</requirement>\n+      <yield/>\n+    </requirements>\n+  </xml>\n+  <token name="@WRAPPER_VERSION@">0.1</token>\n+  <xml name="stdio">\n+    <stdio>\n+      <!-- Anything other than zero is an error -->\n+      <exit_code range="1:"/>\n+      <exit_code range=":-1"/>\n+      <!-- In case the return code has not been set propery check stderr too -->\n+      <regex match="Error:"/>\n+      <regex match="Exception:"/>\n+    </stdio>\n+  </xml>\n+  <token name="@THRESHOLDS@">\n+-E $E\n+--domE $domE\n+\n+#if $T:\n+-T $T\n+#end if\n+\n+#if $domT:\n+--domT $domT\n+#end if\n+\n+#if $incE:\n+--incE $incE\n+#end if\n+\n+#if $incT:\n+--incT $incT\n+#end if\n+\n+#if $incdomE:\n+--incdomE $incdomE\n+#end if\n+\n+#if $incdomT:\n+--incdomT $incdomT\n+#end if\n+  </token>\n+  <xml name="thresholds_xml">\n+    <!-- Options controlling reporting thresholds -->\n+    <param name="E" label="report sequences &lt;= this E-Value threshold in output" help="(-E)" value="10.0" type="float" min="0"/>\n+    <param name="domE" label="report domains &lt;= this E-Value threshold in output" help="(--domE)" value="10.0" type="float" min="0"/>\n+    <param name="T" label="report sequences &gt;= this score threshold in output" help="(-T)" type="float" optional="True"/>\n+    <param name="domT" label="report domains &gt;= this score threshold in output" help="(--domT)" type="float" optional="True"/>\n+    <!-- Options controlling inclusion (significance) thresholds -->\n+    <param name="incE" label="consider sequences &lt;= this E-Value threshold as significant" help="(--incE)" type="float" optional="True"/>\n+    <param name="incdomE" label="consider domains &lt;= this E-Value threshold as significant" help="(--incdomE)" type="float" optional="True"/>\n+    <param name="incT" label="consider sequences &gt;= this score threshold as significant" help="(--incT)" type="float" optional="True"/>\n+    <param name="incdomT" label="consider domains &gt;= this score threshold as significant" help="(--incdomT)" type="float" optional="True"/>\n+  </xml>\n+  <token name="@THRESHOLDS_NODOM@">\n+-E $E\n+\n+#if $T:\n+-T $T\n+#end if\n+\n+#if $incE:\n+--incE $incE\n+#end if\n+\n+#if $incT:\n+--incT $incT\n+#end if\n+  </token>\n+  <xml name="thresholds_nodom">\n+    <!-- Options controlling reporting thresholds -->\n+    <param name="E" label="report sequences &lt;= this E-Value threshold in output" help="(-E)" value="10.0" type="float" min="0"/>\n+    <param name="T" label="report sequences &gt;= this score threshold in output" help="(-T)" type="float" optional="True"/>\n+    <!-- Options controlling inclusion (significance) thresholds -->\n+    <param name="incE" label="consider sequences &lt;= this E-Value threshold as significant" help="(--incE)" type="float" optional="True"/>\n+    <param name="incT" label="consider sequences &gt;= this score threshold as significant" help="(--incT)" type="float" optional="True"/>\n+  </xml>\n+  <token name="@ACCEL_HEUR@">\n+$max\n+--F1 $F1\n+--F2 $F2\n+--F3 $F3\n+$nobias\n+\n+  </token>\n+  <xml name="accel_heur_xml">\n+    <!-- Options controlling acceleration heuristics -->\n+    <param name="max" type="boolean" truevalue="--max" label="Turn all heuristic filters off (less speed, more power)" help="(--max)" falsevalue=""/>\n+    <param name="F1" type="float" label="Stage 1 (MSV) threshold: promote hits w/ P &lt;= F1" help="(--F1)" value="0.02"/>\n+    <param name="F2" type="float" label="Stage 2 (Vit) threshold: promote hits w/ P &lt;= F2" help="(--F2)" value="1e-3"/>\n+    <param name="F3" type="float" label="Stage 3 (Fwd) threshold: promote hits w/ P &lt;= F3" help="(--F3)" value="1e-5"/>\n+    <param name="nobias" type="boolean" truevalue="--nobias" label="Turn off composition bias filter" help="(--nobias)" falsevalue=""/>\n+  </xml>\n+  <token name="@EVAL_CALIB@">\n+--EmL $EmL\n+--EmN $EmN\n+--EvL $EvL\n+--EvN $EvN\n+--EfL $EfL\n+--EfN $EfN\n+--Eft $Eft\n+  </token>\n+  <xml '..b'omain output.\n+\n+**E-value of per target inclusion threshold**\n+\n+Use an E-value of <= <x> as the per-target inclusion threshold. The default is\n+0.01, meaning that on average, about 1 false positive would be expected in\n+every 100 searches with different query sequences.\n+\n+**Bit score of per target inclusion threshold**\n+\n+Instead of using E-values for setting the inclusion threshold, instead use a\n+bit score of >= <x> as the per-target inclusion threshold. It would be unusual\n+to use bit score thresholds with hmmscan, because you don\xe2\x80\x99t expect a single\n+score threshold to work for different profiles; different profiles have\n+slightly different expected score distributions.\n+\n+**domain E-value per target inclusion treshold**\n+\n+Use a conditional E-value of <= <x> as the per-domain inclusion threshold, in\n+targets that have already satisfied the overall per-target inclusion threshold.\n+\n+**domain Bit score per target inclusion treshold**\n+\n+Instead of using E-values, instead use a bit score of >= <x> as the per-domain\n+inclusion threshold. As with --incT above, it would be unusual to use a single\n+bit score threshold in hmmscan.\n+\n+]]></token>\n+  <token name="@THRESHOLDS_NODOM_HELP@"><![CDATA[\n+Options for Reporting Thresholds\n+--------------------------------\n+\n+Reporting thresholds control which hits are reported in output files (the main\n+output, --tblout, and --domtblout).\n+\n+**E-value (-E)**\n+\n+In the per-target output, report target profiles with an E-value of <= <x>. The\n+default is 10.0, meaning that on average, about 10 false positives will be\n+reported per query, so you can see the top of the noise and decide for yourself\n+if it\xe2\x80\x99s really noise.\n+\n+**Bit score (-T)**\n+\n+Instead of thresholding per-profile output on E-value, instead report target profiles\n+with a bit score of >= <x>.\n+\n+Options for Inclusion Thresholds\n+--------------------------------\n+\n+Inclusion thresholds are stricter than reporting thresholds. Inclusion\n+thresholds control which hits are considered to be reliable enough to be\n+included in an output alignment or a subsequent search round. In hmmscan, which\n+does not have any alignment output (like hmmsearch or phmmer) nor any iterative\n+search steps (like jackhmmer), inclusion thresholds have little effect. They\n+only affect what domains get marked as significant (!) or questionable (?) in\n+domain output.\n+\n+**E-value of per target inclusion threshold**\n+\n+Use an E-value of <= <x> as the per-target inclusion threshold. The default is\n+0.01, meaning that on average, about 1 false positive would be expected in\n+every 100 searches with different query sequences.\n+\n+**Bit score of per target inclusion threshold**\n+\n+Instead of using E-values for setting the inclusion threshold, instead use a\n+bit score of >= <x> as the per-target inclusion threshold. It would be unusual\n+to use bit score thresholds with hmmscan, because you don\xe2\x80\x99t expect a single\n+score threshold to work for different profiles; different profiles have\n+slightly different expected score distributions.\n+\n+]]></token>\n+  <token name="@ATTRIBUTION@"><![CDATA[\n+\n+Attribution\n+-----------\n+\n+This Galaxy tool relies on HMMER3_ from http://hmmer.janelia.org/\n+Internally the software is cited as:\n+\n+::\n+\n+    # hmmscan :: search sequence(s) against a profile database\n+    # HMMER 3.1 (February 2013); http://hmmer.org/\n+    # Copyright (C) 2011 Howard Hughes Medical Institute.\n+    # Freely distributed under the GNU General Public License (GPLv3).\n+    # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -\n+\n+The wrappers were written by Eric Rasche and is licensed under Apache2_. The\n+documentation is copied from the HMMER3 documentation.\n+\n+.. _Apache2: http://www.apache.org/licenses/LICENSE-2.0\n+.. _HMMER3: http://hmmer.janelia.org/\n+\n+\n+  ]]></token>\n+  <token name="@HELP_PRE@"><![CDATA[\n+\n+What it does\n+============\n+  ]]></token>\n+  <token name="@HELP_PRE_OTH@"><![CDATA[\n+Options\n+=======\n+  ]]></token>\n+</macros>\n'
b
diff -r 000000000000 -r a6098dd0cb46 nhmmscan.xml
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/nhmmscan.xml Sat Jun 25 15:07:32 2016 -0400
[
@@ -0,0 +1,101 @@
+<?xml version="1.0"?>
+<tool id="hmmer_nhmmscan" name="nhmmscan" version="@WRAPPER_VERSION@.0">
+  <description>search DNA sequence(s) against a DNA profile database</description>
+  <macros>
+    <import>macros.xml</import>
+  </macros>
+  <expand macro="requirements"/>
+  <expand macro="stdio"/>
+  <command><![CDATA[
+hmmpress $hmmfile;
+
+nhmmscan
+
+@OFORMAT_WITH_OPTS_N@
+@THRESHOLDS_NODOM@
+@CUT@
+@ACCEL_HEUR@
+--B1 $B1
+--B2 $B2
+--B3 $B3
+
+@ADV_OPTS@
+@LENGTHS@
+@CPU@
+@SEED@
+
+$hmmfile
+$seqfile
+> $output
+      ]]></command>
+  <inputs>
+    <expand macro="input_hmm" />
+    <!-- todo use Galaxy features like data libraries/data tables/??? -->
+    <param name="seqfile" type="data" format="fasta" label="Sequence file"/>
+    <expand macro="oformat_with_opts_n"/>
+    <expand macro="thresholds_nodom"/>
+    <expand macro="cut"/>
+    <expand macro="accel_heur_xml"/>
+
+    <param name="B1" type="integer" label="window length for biased-composition modifier (MSV)" help="(--B1)" value="110"/>
+    <param name="B2" type="integer" label="window length for biased-composition modifier (Vit)" help="(--B2)" value="240"/>
+    <param name="B3" type="integer" label="window length for biased-composition modifier (Fwd)" help="(--B3)" value="1000"/>
+
+    <expand macro="adv_opts"/>
+    <expand macro="lengths"/>
+    <expand macro="seed"/>
+  </inputs>
+  <outputs>
+    <data format="txt" name="output" label="HMM matches of $seqfile.name in $hmmfile.name"/>
+
+    <data format="txt" name="tblout" label="Table of per-sequence hits from HMM matches of $seqfile.name in $hmmfile.name">
+      <filter>'tblout' in str(oformat)</filter>
+    </data>
+    <data format="txt" name="dfamtblout" label="Table of per-sequence/per-domain hits from HMM matches of $seqfile.name in $hmmfile.name">
+      <filter>'pfamtblout' in str(oformat)</filter>
+    </data>
+    <data format="txt" name="aliscoresout" label="Scores for positional matches of $seqfile.name in $hmmfile.name">
+      <filter>'aliscoresout' in str(oformat)</filter>
+    </data>
+  </outputs>
+  <tests>
+    <test>
+      <param name="hmmfile" value="MADE1.hmm"/>
+      <param name="seqfile" value="dna_target.fa"/>
+      <expand macro="oformat_test" />
+      <expand macro="seed_test" />
+      <output name="output" file="MADE1.out" lines_diff="140"/>
+      <output name="tblout" file="MADE1.out.tblout" lines_diff="30"/>
+      <output name="domtblout" file="MADE1.out.domtblout" lines_diff="30"/>
+      <output name="pfamtblout" file="MADE1.out.pfamtblout" lines_diff="36"/>
+    </test>
+  </tests>
+  <help><![CDATA[
+@HELP_PRE@
+
+nhmmscan is used to search nucleotide sequences against collections of
+nucleotide profiles. For each sequence in <seqfile>, use that query sequence to
+search the target database of profiles in <hmmfile>, and output ranked lists of
+the profiles with the most significant matches to the sequence.
+
+The <seqfile> may contain more than one query sequence. It can be in FASTA
+format, or several other common sequence file formats (genbank, embl, and
+uniprot, among others), or in alignment file formats (stockholm, aligned fasta,
+and others). See the --qformat option for a complete list.
+
+@HELP_PRE_OTH@
+
+@OFORMAT_WITH_OPTS_N_HELP@
+@THRESHOLDS_NODOM_HELP@
+@CUT_HELP@
+@ACCEL_HEUR_HELP@
+@BIAS_COMP_HELP@
+@ADV_OPTS_HELP@
+@LENGTHS_HELP@
+@SEED_HELP@
+
+
+@ATTRIBUTION@
+]]></help>
+  <expand macro="citation"/>
+</tool>
b
diff -r 000000000000 -r a6098dd0cb46 readme.rst
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/readme.rst Sat Jun 25 15:07:32 2016 -0400
b
@@ -0,0 +1,54 @@
+Galaxy wrapper for HMMER3
+=========================
+
+This wrapper is copyright 2015 by Eric Rasche
+
+HMMER is used for searching sequence databases for homologs of protein
+sequences, and for making protein sequence alignments. It implements methods
+using probabilistic models called profile hidden Markov models (profile HMMs).
+
+Compared to BLAST, FASTA, and other sequence alignment and database search
+tools based on older scoring methodology, HMMER aims to be significantly more
+accurate and more able to detect remote homologs because of the strength of its
+underlying mathematical models. In the past, this strength came at significant
+computational expense, but in the new HMMER3 project, HMMER is now essentially
+as fast as BLAST.
+
+http://hmmer.janelia.org/
+http://hmmer.janelia.org/about
+
+
+Installation
+============
+
+The recommended installation is by means of the toolshed_.
+
+.. _toolshed: http://toolshed.g2.bx.psu.edu/view/iuc/hmmer3
+
+
+History
+=======
+
+* v0.1      - Initial public release
+
+
+Licence (MIT)
+=============
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
+AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
+OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN
+THE SOFTWARE.
b
diff -r 000000000000 -r a6098dd0cb46 test-data/MADE1.hmm
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/MADE1.hmm Sat Jun 25 15:07:32 2016 -0400
[
b'@@ -0,0 +1,265 @@\n+HMMER3/f [3.1b2 | February 2015]\n+NAME  MADE1\n+ACC   DF0000629.2\n+DESC  MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon\n+LENG  80\n+MAXL  425\n+ALPH  DNA\n+RF    yes\n+MM    no\n+CONS  yes\n+CS    no\n+MAP   yes\n+DATE  Sat Jun 25 17:24:24 2016\n+NSEQ  1997\n+EFFN  3.911818\n+CKSUM 3015610723\n+STATS LOCAL MSV       -8.5408  0.71858\n+STATS LOCAL VITERBI   -9.6224  0.71858\n+STATS LOCAL FORWARD   -3.4150  0.71858\n+HMM          A        C        G        T   \n+            m->m     m->i     m->d     i->m     i->i     d->m     d->d\n+  COMPO   1.24533  1.59094  1.62722  1.16493\n+          1.38629  1.38629  1.38629  1.38629\n+          0.21058  4.11281  1.75146  1.46634  0.26236  0.00000        *\n+      1   2.69765  2.44396  2.81521  0.24089      1 t x - -\n+          1.38629  1.38629  1.38629  1.38629\n+          0.03960  3.94183  3.94183  1.46634  0.26236  1.10301  0.40327\n+      2   2.72939  2.37873  2.85832  0.24244      2 t x - -\n+          1.38629  1.38629  1.38629  1.38629\n+          0.03725  4.00179  4.00179  1.46634  0.26236  1.21367  0.35255\n+      3   0.16099  3.16370  2.87328  2.99734      3 a x - -\n+          1.38629  1.38629  1.38629  1.38629\n+          0.03604  4.03416  4.03416  1.46634  0.26236  1.32877  0.30762\n+      4   1.98862  2.42132  0.42649  2.10770      4 g x - -\n+          1.38629  1.38629  1.38629  1.38629\n+          0.03539  4.05203  4.05203  1.46634  0.26236  1.35213  0.29933\n+      5   1.96369  2.69532  0.36534  2.32099      5 g x - -\n+          1.38629  1.38629  1.38629  1.38629\n+          0.03764  4.06427  3.92372  1.46634  0.26236  1.00259  0.45717\n+      6   2.56994  2.11239  2.71946  0.30571      6 t x - -\n+          1.37159  1.41129  1.39124  1.37159\n+          0.03806  3.89715  4.07214  1.50442  0.25122  1.12269  0.39364\n+      7   2.58388  2.10353  2.64646  0.31253     12 t x - -\n+          1.38764  1.38524  1.38764  1.38465\n+          0.03494  4.03864  4.09125  1.40070  0.28293  1.44046  0.27026\n+      8   2.18552  2.70201  0.28821  2.64645     14 g x - -\n+          1.38629  1.38629  1.38629  1.38629\n+          0.03628  4.09157  3.96779  1.46634  0.26236  1.26997  0.32967\n+      9   2.16916  2.82142  0.28427  2.60854     15 g x - -\n+          1.38091  1.39033  1.38365  1.39033\n+          0.03566  4.00237  4.08886  1.38021  0.28972  1.26961  0.32981\n+     10   2.45517  2.15232  2.42886  0.34277     18 t x - -\n+          1.39065  1.39065  1.39065  1.37335\n+          0.03536  4.01212  4.09576  1.39554  0.28462  1.25024  0.33748\n+     11   2.10260  2.95484  0.28160  2.64222     21 g x - -\n+          1.36740  1.40555  1.40555  1.36740\n+          0.03843  3.92069  4.02468  1.44733  0.26814  1.15789  0.37709\n+     12   2.54740  0.30185  2.61355  2.21647     26 c x - -\n+          1.38748  1.38276  1.38748  1.38748\n+          0.03457  4.05446  4.09623  1.40847  0.28040  1.17686  0.36852\n+     13   0.28443  2.72003  2.32214  2.48149     28 a x - -\n+          1.38740  1.38740  1.38298  1.38740\n+          0.03441  4.05976  4.10001  1.41198  0.27926  0.97690  0.47237\n+     14   0.29412  2.55413  2.49679  2.35701     30 a x - -\n+          1.38194  1.39067  1.38194  1.39067\n+          0.03505  4.02482  4.10005  1.39522  0.28473  1.16906  0.37202\n+     15   0.18837  2.99710  2.82270  2.77556     33 a x - -\n+          1.39015  1.39472  1.37503  1.38539\n+          0.03725  3.97815  4.02618  1.37955  0.28994  1.16870  0.37218\n+     16   0.50816  2.05151  2.22111  1.82407     37 a x - -\n+          1.36727  1.38730  1.39683  1.39405\n+          0.04830  3.89881  3.61610  1.29026  0.32186  1.08301  0.41336\n+     17   2.11260  2.73141  0.29747  2.64152     41 g x - -\n+          1.36913  1.40376  1.40376  1.36913\n+          0.03705  3.93681  4.08299  1.44872  0.26771  1.09472  0.40742\n+     18   2.24459  1.90539  2.34054  0.43234     46 t x - -\n+          1.33632  1.42493  1.39937  1.38665\n+          0.04427  3.64574  4.06297  1.70501  0.20061  1.19872  0.35894\n+     19   0.44322  2.17202  2.18055'..b'2.20911  0.11631  1.00864  0.45368\n+     59   0.41659  2.44509  1.93972  2.20507   1034 a x - -\n+          1.38198  1.38198  1.39194  1.38932\n+          0.03641  3.98130  4.06929  1.35873  0.29704  1.31330  0.31325\n+     60   0.41612  2.39160  1.97116  2.21075   1037 a x - -\n+          1.03649  1.46430  1.57421  1.57557\n+          0.04787  3.52599  4.05584  2.32461  0.10294  0.84329  0.56263\n+     61   2.66264  2.12302  2.82746  0.28581   1056 t x - -\n+          1.36925  1.39635  1.38930  1.39048\n+          0.04103  3.97406  3.84419  1.39433  0.28502  1.12555  0.39227\n+     62   2.26510  2.13196  2.42551  0.37231   1060 t x - -\n+          1.37965  1.39147  1.39147  1.38264\n+          0.04136  3.91664  3.88204  1.24613  0.33914  0.95630  0.48501\n+     63   0.41244  2.25761  2.16787  2.12907   1062 a x - -\n+          1.34515  1.41203  1.41203  1.37753\n+          0.04086  3.77867  4.06371  1.30483  0.31638  1.13245  0.38897\n+     64   2.51464  0.37905  2.62296  1.82008   1068 c x - -\n+          1.39543  1.38753  1.39233  1.37008\n+          0.03884  3.90614  4.01884  1.36573  0.29463  1.15716  0.37743\n+     65   2.16380  2.11332  2.18714  0.42765   1073 t x - -\n+          1.38764  1.38471  1.38519  1.38764\n+          0.03603  4.05405  4.01529  1.40080  0.28289  1.06383  0.42332\n+     66   2.79349  2.39141  2.87271  0.23478   1075 t x - -\n+          1.37227  1.39101  1.39101  1.39101\n+          0.03884  4.01734  3.90722  1.39017  0.28639  1.09574  0.40690\n+     67   2.82488  2.47749  2.93179  0.21887   1078 t x - -\n+          1.38141  1.39112  1.38915  1.38353\n+          0.03675  3.99492  4.03549  1.35958  0.29675  1.21867  0.35044\n+     68   2.77679  2.30433  2.90694  0.24425   1081 t x - -\n+          1.37593  1.38989  1.45520  1.32825\n+          0.04566  3.68855  3.93098  1.76176  0.18843  1.07133  0.41939\n+     69   2.47698  3.17398  0.19595  2.95437   1093 g x - -\n+          1.38264  1.38264  1.39734  1.38264\n+          0.05482  3.96677  3.36946  1.40348  0.28202  1.13963  0.38557\n+     70   2.84327  0.27906  2.97336  2.00890   1097 c x - -\n+          1.38629  1.38629  1.38629  1.38629\n+          0.03475  4.08873  4.05197  1.46634  0.26236  0.79234  0.60291\n+     71   0.21870  2.83638  2.69251  2.65798   1098 a x - -\n+          1.37446  1.37942  1.39640  1.39509\n+          0.04066  3.94379  3.88865  1.41905  0.27700  1.24551  0.33939\n+     72   2.35233  0.46085  2.23804  1.78715   1103 c x - -\n+          1.38536  1.38781  1.38781  1.38421\n+          0.03885  4.04214  3.88532  1.39310  0.28542  1.30851  0.31501\n+     73   2.57111  0.32543  2.74124  1.98892   1105 c x - -\n+          1.38629  1.38629  1.38629  1.38629\n+          0.03403  4.09710  4.08422  1.46634  0.26236  1.37004  0.29316\n+     74   0.27014  2.61416  2.53262  2.47636   1106 a x - -\n+          1.38629  1.38629  1.38629  1.38629\n+          0.03889  4.09695  3.83874  1.46634  0.26236  1.37489  0.29151\n+     75   0.52873  2.16549  1.91736  1.90409   1107 a x - -\n+          1.38629  1.38629  1.38629  1.38629\n+          0.04237  4.09207  3.69758  1.46634  0.26236  1.41112  0.27954\n+     76   2.33134  0.38082  2.65861  1.90055   1108 c x - -\n+          1.38629  1.38629  1.38629  1.38629\n+          0.04659  4.08459  3.55121  1.46634  0.26236  1.54765  0.23921\n+     77   2.20588  0.45134  2.35553  1.84373   1109 c x - -\n+          1.38629  1.38629  1.38629  1.38629\n+          0.05904  4.07266  3.21140  1.46634  0.26236  1.68734  0.20458\n+     78   2.69018  2.22054  2.82311  0.26898   1110 t x - -\n+          1.38629  1.38629  1.38629  1.38629\n+          0.08061  4.04912  2.81320  1.46634  0.26236  1.91269  0.15980\n+     79   0.16248  3.15867  2.86159  2.98963   1111 a x - -\n+          1.38629  1.38629  1.38629  1.38629\n+          0.12592  4.00561  2.30158  1.46634  0.26236  2.22059  0.11490\n+     80   0.17484  3.04770  2.86638  2.88183   1112 a x - -\n+          1.38629  1.38629  1.38629  1.38629\n+          0.02045  3.90014        *  1.46634  0.26236  0.00000        *\n+//\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/MADE1.out
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/MADE1.out Sat Jun 25 15:07:32 2016 -0400
[
@@ -0,0 +1,87 @@
+# hmmscan :: search sequence(s) against a profile database
+# HMMER 3.1b2 (February 2015); http://hmmer.org/
+# Copyright (C) 2015 Howard Hughes Medical Institute.
+# Freely distributed under the GNU General Public License (GPLv3).
+# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
+# query sequence file:             /tmp/tmpYWzicI/files/000/dataset_20.dat
+# target HMM database:             /tmp/tmpYWzicI/files/000/dataset_19.dat
+# per-seq hits tabular output:     /tmp/tmpYWzicI/files/000/dataset_22.dat
+# per-dom hits tabular output:     /tmp/tmpYWzicI/files/000/dataset_23.dat
+# pfam-style tabular hit output:   /tmp/tmpYWzicI/files/000/dataset_24.dat
+# max ASCII text line length:      unlimited
+# Vit filter P threshold:       <= 0.001
+# Fwd filter P threshold:       <= 1e-05
+# random number seed set to:       4
+# number of worker threads:        1
+# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
+
+Query:       humanchr1/239220001-239550000  [L=330000]
+Scores for complete sequence (score includes all domains):
+   --- full sequence ---   --- best 1 domain ---    -#dom-
+    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
+    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
+      1e-17   51.0  28.5    2.7e-12   33.7   0.7    9.6  5  MADE1     MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon
+
+
+Domain annotation for each model (and alignments):
+>> MADE1  MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon
+   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
+ ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
+   1 ?   -4.2   0.1         1         1      30      54 ..   80044   80068 ..   80030   80073 .. 0.80
+   2 ?   -6.6   3.3         1         1      13      71 ..  154012  154072 ..  154011  154076 .. 0.75
+   3 !   27.4   0.7   2.4e-10   2.4e-10       1      44 [.  174456  174514 ..  174456  174577 .. 0.62
+   4 !   33.7   0.7   2.7e-12   2.7e-12       2      80 .]  302388  302466 ..  302387  302466 .. 0.86
+   5 ?    2.9   0.7     0.011     0.011      27      75 ..  304060  304107 ..  304021  304109 .. 0.61
+
+  Alignments for each domain:
+  == domain 1  score: -4.2 bits;  conditional E-value: 1
+                                      xxxxxxxxxxxxxxxxxxxxxxxxx RF
+                          MADE1    30 ttgccattacttttaatggcaaaaa 54
+                                      t g catt  ttt aatggcaaa a
+  humanchr1/239220001-239550000 80044 TAGTCATTCATTTCAATGGCAAATA 80068
+                                      45789****************9966 PP
+
+  == domain 2  score: -6.6 bits;  conditional E-value: 1
+                                       xxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
+                          MADE1     13 aaaagtaattgcggtttttgccatt......acttttaatggcaaaaaccgcaattacttttgca 71
+                                       aaaagta tt +   ttttgc att      a  tttaa  gcaaa a +    tta  tttgca
+  humanchr1/239220001-239550000 154012 AAAAGTAGTTTTCAATTTTGCAATTtgaccaATATTTAAATGCAAATATT----TTATATTTGCA 154072
+                                       78999999999999999999999984444444457777777899998876....77777888876 PP
+
+  == domain 3  score: 27.4 bits;  conditional E-value: 2.4e-10
+                                       xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...............x RF
+                          MADE1      1 ttaggttggtgcaaaagtaattgcggtttttgccattactttt...............a 44
+                                       ttaggtt gtgcaaaagtaattg+ggtttttg cattactttt               a
+  humanchr1/239220001-239550000 174456 TTAGGTTAGTGCAAAAGTAATTGTGGTTTTTGTCATTACTTTTctgcatgctagaagtA 174514
+                                       79***************************************964443333333333330 PP
+
+  == domain 4  score: 33.7 bits;  conditional E-value: 2.7e-12
+                                       xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
+                          MADE1      2 taggttggtgcaaaagtaattgcggtttttgccattacttttaatggcaaaaaccgcaattacttttgcaccaacctaa 80
+                                       t ggt ggtgcaaaa  aattg+ggtttttgccatt cttttaat gc    a  +  a t ctttt caccaa ctaa
+  humanchr1/239220001-239550000 302388 TTGGTCGGTGCAAAATCAATTGTGGTTTTTGCCATTGCTTTTAATTGCTTTTAAAAGTAATGCTTTTACACCAATCTAA 302466
+                                       56899******************************************963333233345578**************996 PP
+
+  == domain 5  score: 2.9 bits;  conditional E-value: 0.011
+                                       xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
+                          MADE1     27 tttttgccattacttttaatggcaaaaaccgcaattacttttgcaccaa 75
+                                       tttt g c  ta  tt a tgg aaaaa ++ca tta ttttgca  aa
+  humanchr1/239220001-239550000 304060 TTTTAGACTATA-GTTAAGTGGGAAAAAATACACTTATTTTTGCATTAA 304107
+                                       222222222222.3455779************************98765 PP
+
+
+
+Internal pipeline statistics summary:
+-------------------------------------
+Query sequence(s):                         1  (330000 residues searched)
+Target model(s):                           1  (80 nodes)
+Passed MSV filter:                         1  (1); expected 0.0 (0.02)
+Passed bias filter:                        1  (1); expected 0.0 (0.02)
+Passed Vit filter:                         1  (1); expected 0.0 (0.001)
+Passed Fwd filter:                         1  (1); expected 0.0 (1e-05)
+Initial search space (Z):                  1  [actual number of targets]
+Domain search space  (domZ):               1  [number of targets reported over threshold]
+# CPU time: 0.15u 0.00s 00:00:00.15 Elapsed: 00:00:00.16
+# Mc/sec: 165.00
+//
+[ok]
b
diff -r 000000000000 -r a6098dd0cb46 test-data/MADE1.out.domtblout
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/MADE1.out.domtblout Sat Jun 25 15:07:32 2016 -0400
[
@@ -0,0 +1,18 @@
+#                                                                                      --- full sequence --- -------------- this domain -------------   hmm coord   ali coord   env coord
+# target name        accession    tlen query name                    accession   qlen   E-value  score  bias   #  of  c-Evalue  i-Evalue  score  bias  from    to  from    to  from    to  acc description of target
+#-------------------  ---------- -----          -------------------- ---------- ----- --------- ------ ----- --- --- --------- --------- ------ ----- ----- ----- ----- ----- ----- ----- ---- ---------------------
+MADE1                DF0000629.2    80 humanchr1/239220001-239550000 -          330000     1e-17   51.0  28.5   1   5         1         1   -4.2   0.1    30    54 80044 80068 80030 80073 0.80 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon
+MADE1                DF0000629.2    80 humanchr1/239220001-239550000 -          330000     1e-17   51.0  28.5   2   5         1         1   -6.6   3.3    13    71 154012 154072 154011 154076 0.75 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon
+MADE1                DF0000629.2    80 humanchr1/239220001-239550000 -          330000     1e-17   51.0  28.5   3   5   2.4e-10   2.4e-10   27.4   0.7     1    44 174456 174514 174456 174577 0.62 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon
+MADE1                DF0000629.2    80 humanchr1/239220001-239550000 -          330000     1e-17   51.0  28.5   4   5   2.7e-12   2.7e-12   33.7   0.7     2    80 302388 302466 302387 302466 0.86 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon
+MADE1                DF0000629.2    80 humanchr1/239220001-239550000 -          330000     1e-17   51.0  28.5   5   5     0.011     0.011    2.9   0.7    27    75 304060 304107 304021 304109 0.61 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon
+#
+# Program:         hmmscan
+# Version:         3.1b2 (February 2015)
+# Pipeline mode:   SCAN
+# Query file:      /tmp/tmpYWzicI/files/000/dataset_2.dat
+# Target file:     /tmp/tmpYWzicI/files/000/dataset_1.dat
+# Option settings: hmmscan --tblout /tmp/tmpYWzicI/files/000/dataset_4.dat --domtblout /tmp/tmpYWzicI/files/000/dataset_5.dat --pfamtblout /tmp/tmpYWzicI/files/000/dataset_6.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 1 /tmp/tmpYWzicI/files/000/dataset_1.dat /tmp/tmpYWzicI/files/000/dataset_2.dat 
+# Current dir:     /tmp/tmpYWzicI/job_working_directory/000/3
+# Date:            Sat Jun 25 19:05:15 2016
+# [ok]
b
diff -r 000000000000 -r a6098dd0cb46 test-data/MADE1.out.pfamtblout
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/MADE1.out.pfamtblout Sat Jun 25 15:07:32 2016 -0400
[
@@ -0,0 +1,27 @@
+# Sequence scores
+# ---------------
+#
+# name                  bits   E-value   n   exp  bias    description
+# ------------------- ------ --------- --- ----- -----    ---------------------
+MADE1                   51.0     1e-17   5   9.6  28.5    MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon
+
+# Domain scores
+# -------------
+#
+#  name                 bits   E-value   hit  bias env-st env-en ali-st ali-en hmm-st hmm-en     description
+# ------------------- ------ --------- ----- ----- ------ ------ ------ ------ ------ ------      ---------------------
+MADE1                   33.7   2.7e-12     4   0.7 302387 302466 302388 302466      2     80     MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon
+MADE1                   27.4   2.4e-10     3   0.7 174456 174577 174456 174514      1     44     MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon
+MADE1                    2.9     0.011     5   0.7 304021 304109 304060 304107     27     75     MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon
+MADE1                   -4.2         1     1   0.1  80030  80073  80044  80068     30     54     MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon
+MADE1                   -6.6         1     2   3.3 154011 154076 154012 154072     13     71     MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon
+#
+# Program:         hmmscan
+# Version:         3.1b2 (February 2015)
+# Pipeline mode:   SEARCH
+# Query file:      /tmp/tmpYWzicI/files/000/dataset_2.dat
+# Target file:     /tmp/tmpYWzicI/files/000/dataset_1.dat
+# Option settings: hmmscan --tblout /tmp/tmpYWzicI/files/000/dataset_4.dat --domtblout /tmp/tmpYWzicI/files/000/dataset_5.dat --pfamtblout /tmp/tmpYWzicI/files/000/dataset_6.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 1 /tmp/tmpYWzicI/files/000/dataset_1.dat /tmp/tmpYWzicI/files/000/dataset_2.dat 
+# Current dir:     /tmp/tmpYWzicI/job_working_directory/000/3
+# Date:            Sat Jun 25 19:05:15 2016
+# [ok]
b
diff -r 000000000000 -r a6098dd0cb46 test-data/MADE1.out.tblout
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/MADE1.out.tblout Sat Jun 25 15:07:32 2016 -0400
[
@@ -0,0 +1,14 @@
+#                                                                         --- full sequence ---- --- best 1 domain ---- --- domain number estimation ----
+# target name        accession   query name                    accession    E-value  score  bias   E-value  score  bias   exp reg clu  ov env dom rep inc description of target
+#-------------------  ----------          -------------------- ---------- --------- ------ ----- --------- ------ -----   --- --- --- --- --- --- --- --- ---------------------
+MADE1                DF0000629.2 humanchr1/239220001-239550000 -            7.1e-18   51.5  28.5     2e-12   34.0   0.7   9.6   5   0   0   5   5   5   2 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon
+#
+# Program:         hmmscan
+# Version:         3.1b1 (May 2013)
+# Pipeline mode:   SCAN
+# Query file:      test-data/dna_target.fa
+# Target file:     test-data/MADE1.hmm
+# Option settings: hmmscan --tblout tblout --domtblout domtblout --pfamtblout pfamtblout test-data/MADE1.hmm test-data/dna_target.fa 
+# Current dir:     /home/users/cpt/cpt/esr/Projects/galaxy/tools-iuc/tools/hmmer
+# Date:            Tue Feb 10 14:40:35 2015
+# [ok]
b
diff -r 000000000000 -r a6098dd0cb46 test-data/MADE1.sto
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/MADE1.sto Sat Jun 25 15:07:32 2016 -0400
[
b'@@ -0,0 +1,4021 @@\n+# STOCKHOLM 1.0\n+#=GF ID   MADE1\n+#=GF AC   DF0000629.2\n+#=GF DE   MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon\n+#=GF AU   Finn RD, Hubley R, Jones T, Jurka J, Smit A, Wheeler T\n+#=GF SE   Repbase\n+#=GF GA   15.98;\n+#=GF TC   32.00;\n+#=GF NC   15.90;\n+#=GF BM   hmmbuild --hand --maxinsertlen 10 HMM.ann SEED.ann\n+#=GF SM   nhmmer -Z 3102 --dfamtblout DFAMOUT -E 100  --noali HMM.ann\n+#=GF SM   dfamseq\n+#=GF CT   Type; DNA Transposon;\n+#=GF CT   Class; Cut and Paste;\n+#=GF CT   Superfamily; TcMar-Mariner;\n+#=GF MS   TaxId:9606 TaxName:Homo sapiens\n+#=GF RN   [1]\n+#=GF RM   8643651\n+#=GF RT   Tiggers and DNA transposon fossils in the human genome.\n+#=GF RA   Smit AF, Riggs AD;\n+#=GF RL   Proc Natl Acad Sci U S A 1996;93:1443-1448\n+#=GF DR   Repbase; MADE1;\n+#=GF CC   Resembles an internal deletion product of Mariner1; has 37 bp\n+#=GF CC   TIRs and a TA target site.\n+#=GF SQ   1997\n+#=GS H.sapiens_13.1/49567006-49566901     DE 13 dna:chromosome chromosome:GRCh37:13:1:115169878:1\n+#=GS H.sapiens_8.1/107923792-107923714    DE 8 dna:chromosome chromosome:GRCh37:8:1:146364022:1\n+#=GS H.sapiens_6.1/35544547-35544476      DE 6 dna:chromosome chromosome:GRCh37:6:1:171115067:1\n+#=GS H.sapiens_8.1/33053357-33053450      DE 8 dna:chromosome chromosome:GRCh37:8:1:146364022:1\n+#=GS H.sapiens_7.1/137095299-137095226    DE 7 dna:chromosome chromosome:GRCh37:7:1:159138663:1\n+#=GS H.sapiens_19.1/19100550-19100497     DE 19 dna:chromosome chromosome:GRCh37:19:1:59128983:1\n+#=GS H.sapiens_1.1/164701792-164701870    DE 1 dna:chromosome chromosome:GRCh37:1:1:249250621:1\n+#=GS H.sapiens_3.1/68038940-68038866      DE 3 dna:chromosome chromosome:GRCh37:3:1:198022430:1\n+#=GS H.sapiens_Y.1/16255032-16255111      DE Y dna:chromosome chromosome:GRCh37:Y:1:10000:1\n+#=GS H.sapiens_11.1/78684849-78684770     DE 11 dna:chromosome chromosome:GRCh37:11:1:135006516:1\n+#=GS H.sapiens_9.1/102803629-102803549    DE 9 dna:chromosome chromosome:GRCh37:9:1:141213431:1\n+#=GS H.sapiens_7.1/70331740-70331819      DE 7 dna:chromosome chromosome:GRCh37:7:1:159138663:1\n+#=GS H.sapiens_12.1/65806432-65806356     DE 12 dna:chromosome chromosome:GRCh37:12:1:133851895:1\n+#=GS H.sapiens_4.1/140063757-140063828    DE 4 dna:chromosome chromosome:GRCh37:4:1:191154276:1\n+#=GS H.sapiens_2.1/145673253-145673319    DE 2 dna:chromosome chromosome:GRCh37:2:1:243199373:1\n+#=GS H.sapiens_8.1/75316483-75316561      DE 8 dna:chromosome chromosome:GRCh37:8:1:146364022:1\n+#=GS H.sapiens_10.1/58241727-58241653     DE 10 dna:chromosome chromosome:GRCh37:10:1:135534747:1\n+#=GS H.sapiens_10.1/9215317-9215239       DE 10 dna:chromosome chromosome:GRCh37:10:1:135534747:1\n+#=GS H.sapiens_3.1/5959133-5959195        DE 3 dna:chromosome chromosome:GRCh37:3:1:198022430:1\n+#=GS H.sapiens_5.1/123101247-123101157    DE 5 dna:chromosome chromosome:GRCh37:5:1:180915260:1\n+#=GS H.sapiens_X.1/35165291-35165214      DE X dna:chromosome chromosome:GRCh37:X:1:155270560:1\n+#=GS H.sapiens_1.1/178351842-178351911    DE 1 dna:chromosome chromosome:GRCh37:1:1:249250621:1\n+#=GS H.sapiens_5.1/109325838-109325779    DE 5 dna:chromosome chromosome:GRCh37:5:1:180915260:1\n+#=GS H.sapiens_3.1/108039241-108039320    DE 3 dna:chromosome chromosome:GRCh37:3:1:198022430:1\n+#=GS H.sapiens_3.1/11149279-11149387      DE 3 dna:chromosome chromosome:GRCh37:3:1:198022430:1\n+#=GS H.sapiens_9.1/76348944-76348881      DE 9 dna:chromosome chromosome:GRCh37:9:1:141213431:1\n+#=GS H.sapiens_4.1/13679946-13679866      DE 4 dna:chromosome chromosome:GRCh37:4:1:191154276:1\n+#=GS H.sapiens_3.1/50865115-50865038      DE 3 dna:chromosome chromosome:GRCh37:3:1:198022430:1\n+#=GS H.sapiens_3.1/142708263-142708322    DE 3 dna:chromosome chromosome:GRCh37:3:1:198022430:1\n+#=GS H.sapiens_14.1/99520157-99520073     DE 14 dna:chromosome chromosome:GRCh37:14:1:107349540:1\n+#=GS H.sapiens_8.1/49894414-49894352      DE 8 dna:chromosome chromosome:GRCh37:8:1:146364022:1\n+#=GS H.sapiens_22.1/33739050-33738973     DE 22 dna'..b'......T.............T................T....................................T............................A.........................A......................AT......................................G...........................G...............................C........A...................A.............................A...........................A......................A.........................C......................T...............G.................C................A..A..................C...T.A.....C....T.T..T..T...........G...CA....T.CAACCTA.\n+H.sapiens_Y.1/15779845-15779925      TTAGGT.....T.AG..T..G....C.G.A..T...A...G....T..........A........A.......T.........T...G.T...............G........................G...................T..................T.......................T....................T................................T...............................G....................................C.............................C........................................A..................................................T.........................T..............................................A.....................................C...........................T.............T................T....................................C............................A........................TA.......................T......................................G...........................G...............................C........A...................A.............................A...........................A......................A.........................G......................C...............A.................C................A..A..................T...T.A.....C....T.T..T..T...........G...CA....C.CAAGCTAA\n+H.sapiens_14.1/99179197-99179121     .TAGGT.....T.GG..T..G....C.A.A..A...A...G....T..........A........A.......T.........C...G.T...............G........................A...................T..................T.......................T....................T................................................................G....................................C.............................C........................................A..................................................T.........................T....................................................................................C...........................T.............T................T....................................T............................A.........................A.......................T......................................G...........................G...............................T........G...................A.............................A...........................A......................A.........................C......................C...............A.................C................A..A..................T...T.A.....C....T.T..T..T...........G...CA....C.CAACCTAA\n+#=GC RF                              xxxxxx.....x.xx..x..x....x.x.x..x...x...x....x..........x........x.......x.........x...x.x...............x........................x...................x..................x.......................x....................x................................x...............................x....................................x.............................x........................................x..................................................x.........................x..............................................x.....................................x...........................x.............x................x....................................x............................x.........................x.......................x......................................x...........................x...............................x........x...................x.............................x...........................x......................x.........................x......................x...............x.................x................x..x..................x...x.x.....x....x.x..x..x...........x...xx....x.xxxxxxxx\n+//\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/dna_target.fa
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/dna_target.fa Sat Jun 25 15:07:32 2016 -0400
b
b'@@ -0,0 +1,5501 @@\n+>humanchr1/239220001-239550000 \n+CCAAAAATACGAAAAAGTAGCCAGGCATAATGGCACACATGTGTGGTCCCGCTGCTTGGG\n+AGGCCGAGGTGGGAGGATCGCTTGAGCTCGGAAGGCAGAGATTGCAGTGAGCTGAAATCC\n+CACCACTGCACTCCAGCATGGGTGACAAAGCAAGACTCTGTCTCACCAAAAAAAAAAAAA\n+AAAAGAAGGAACTGGCAGAGTCCCAACTGACAGGTATATTTTCTGTTGACCAAAATACGG\n+TTCTTACTGATATTTGATACTGACTCATAGTCACAACTGCCATATGAAAAGAGAGAGATC\n+ATTTTTTTTTCCTGGCAATATGTGATGGTGGAAGATACTTAGTGTGGTGTCCTGATAAGA\n+TAAGTAAGCAACAATGAGGAGGGAACCCCAGGGAGGGAGGACCATTGTTCCGAGAGAACA\n+GCTAATCACAGACAACCTGTTGGCAGGACATCCTGTTCCCAAATGCCTTGCTTGGCAAGT\n+AGGCCCAGCAGCAGGACCTCATTGTGCAGGTGGCCCCCTCCAGCATGATCCTATAAAACT\n+TCCCTCCAGCCCCCGCCTCTTGGCGGACAGACTTCTCTCTGCTGCACTGCCCATTGCTTT\n+CTTGCAATCTTTGTACTTTCCCTAATAAATCTGCCTTTCCTTACCCATGACTGTCTGTCT\n+TGGTAAATTCTTTTACCTCCCACGACACCAGCCACAGCCAGTTGCACTCACAGCACTTAG\n+GAAAATAAAAAAAATCAAGGCTGACACTCTGGATACCAATATGTAATGAAGTGTTCTTCT\n+TACAAGAGCTTATGAGATAAATAGAAACGTAACAACAATTTTTATTAAGCAAGATATAAA\n+AACTTCACCATAGGCTGATCCTGTTTTCATTCATGGAAGATAAATACTATCCCTCACTTA\n+AGAGCTTTTTGTGTAGGAATTCTTCTTCCTTATTTTTTCACGAATAAAGATAGGGATGTC\n+CTTAGCATCCAAAATCAGTCAAAAAAAAATTGACATTTCATGTCCTGGTTAGACTACTCT\n+GGCAGCTTGCTGGAATGGTCACTTGCTTCTCCCAACTGGATCTCAAGTCCAGACCCCTTT\n+GTTGTCGGCCCCCCTCCTGGCCACCCCCACCACAATCACTTAATAAGAAATACCAGCTGT\n+AGAGCTCAGAACTGCTATGACAATTAAAGCTTCCCACCTTCATGAAAACTGTTGAAAATG\n+GGGCAGAACAAAAAGTAGTGTGACAGAATTTCTCTATACTGTCTGATGCATTGCTTCCAA\n+TGTAGGGAGACCTTTAATTGGTTCTCTGGCTTTTGGTTCCATCCTATTGTAAACAAAGAA\n+TCAAAGTATAGTAAGGTTCAAAGAAGTAGGGAGTGCTGAATTTGGCAGATGGCACAAGAC\n+ATGGTTAGAAAGAAAGCATCCTCAGAGGAGATGAGAATGATGCTGAGCCTTGGCAAATTG\n+CAAGGAATGCGTAGTTAAGCAGAGCAACTTTTCACAGTCAGATTTAGAGTATAACTAACT\n+CTGGAATGACGAGACACACAAAAAGATAAATGCTATTTATCACCACTGCTCACAATGAGG\n+AATCAGTAAGCAGCCATAACAGATGCTGCGCTGCCCAGATCCCCTCCTTAGGACTGAGGT\n+GCTCACTTGCCAGCTGCAAAGACTCGTGCCTGAGTCTCTCTCCAGGCAATGTTCTCAGGT\n+CAAAAGGCAGCTGCCCTGCTGGAGGTTATAGCTCCATCCAGCGGCATGCAGAATCCATTG\n+ATTAGCAGATGTGGGCATATGAAGACAATGTCTTGGCTCAAATTAGAACGGTTCTAAAAT\n+TGCTGCGACCCTGGCTAGAATTACATTGCAGGTGAGCTTCTTCCTCCATCCAGTCCTGTT\n+TCTCTCACTCCATTACAGTTGTGATTCCCAAGAGCACTTCACAATAAACCTCCAGCACAC\n+AGTCTCCTTCTCTGAGTCTCTTTCTAGGAAAGCCTGACCTAAGACAACAGCCTCCCTATG\n+GCAAAAATGTCCAAATTAATAGCTTCTTTATATAGGGGGCAAAACCACCAGCAACCAAAA\n+CTTTTATTTAAAAAAATGACAATTGTATGACTAATCAGCGTACATTTAACTTCAGGATTG\n+AAAATGTTGCATCCTGAGCTTAATTTCCTTGATTTTACTTTGAACACTCTTTGAGTTGTG\n+TTTCTATTTTTAGACCACAGAATTTAAGATAAATGTGCATAATTTAGAGAGGTTTCAAAG\n+AAAGGCAAGTCAAGTGATTAAATAATGAGAATAAAATTAGTATAAAAAGTGCCAGGAACA\n+TTTGGTCTTTTGAAAGGAAGGGCAAGGGGGCCATTTTAATAACAGCCTTCACATACATGC\n+CTACTTATTCAGATAGACGGTTGTGAGGTCAAGCTGGAGGGGCAGATAGGGATCCGATCA\n+CTATAGACCCAGATTCCTGCGGTAGCTTCCTACATTATCTCCCAGCTTTCACCCTCCTGG\n+CAACATCCAGAGTGATCCTTGAGAAACCATAACAAATCACATCGCTCTTCACCTCCAATC\n+CACCTCTTCACTCTCCATCAGTCCTTCTTATGAACTACACACACTCTGTGATCAAGCCCT\n+GGCTGCCTCTAGGGATTGTCTCCTCCCATTCACCACTACAAAACTTCTTCCTCGAAGGTG\n+TCCAGCAGGCCAAGCCACGCTGGACTCAGGGATCTCCCCACGGCTGTGTTCTTCCCATAG\n+TACCACAAACCCTCCACTCCATTCACTTATCTGCTCAATGGCACCTCCTGTGAAAGGATT\n+TAAAGTAGCCCTCCTCGTGATGTTTTATTCCCTTACTTTGCTTTACAAGCCATCAGAGCA\n+TTTATTACTTCTTGATATTCTAATTCTAATATGCTAACGTTATATTTTCTATATATACCA\n+TTAAATATGGAGAGAATGGATAGATATAGATTTAGATAGCTGATACAGGTAAATATAGAC\n+AGAGGTAAAAATATAGATAGAGACTCTTTCATTTAGTCCTACGTGCCCATCAAAATGTAA\n+GCTCCGTAAGGGTAGGATCTTTGTCTCTTAGTTAACTCCTCTATGGTGGAGGAGATGTGA\n+GACAACCAGAAATTTCTGTCTAAAAAAAAAAATCACACACTCGATCACACACTCGATAGG\n+TGTTCAATCAATATTTGGTGACTGAATGAATGGATGAATGTGATCCCTTTAAATCTGTAT\n+CCTCACTATACAAACTTCCTTAAATATCTATTAGGTAATTTAGCTAAACTTTTCTTACTC\n+GCTCCAGTGTGGTGTGTGTTTGTCTTTTCTTCCTCCTTGACCTATAACTATTGACAGTTA\n+TACAATATGGTGGTTCCACAGCCACCAGCCTCCTTTTCCTATTCTCTAGAAAGAACGAGG\n+ATGAGCTATAAAATTCATCTAACCCTATCATCTTTTTAAGGGGTATAATATTAAGTGGAA\n+ATTCTTTACAAATTTAAAGTTATATTCAATTTGTAAATAAGAATAATTATTATTGCCTGT\n+AACTTTTGAACTTGGCCCATCTCGTTTCTGCCTTCTTGAAATTCGGTATTTTTTATTAGA\n+GCTTTCAGAGTCAGCTTTTGATTTTATTGATCTTTTTTGTTTTGTTTTTATTTATGTTCT\n+TGTCTTTTTAACTTACATTGTGTGTGTATTCTTATTTATGTTCTTGTCTTTTTAACTTAG\n+ATTTTTGTATGTATTCTTTTCTTTATTTCTACCTCCTACAATGGAATACCCAGTTATTTT\n+TTATATATATGATATATATATGGCATATATATGACATATATGTATGTCTTTCTTACTTAT\n+ATTTTTAAGTCTTTACTTCTAACTTCTAGAATGGAATATA'..b'CTTGTGCAGGGAAATTCCCATTATTAAAAC\n+CATCAGATCTCATGAGACTTATTCACTGTCATGAGAACAGTACGGGAAAGACCTACATGA\n+TTCAATTATCTCCCTCCCACAACATGTGGGAATTATGGGAGCTACAAGATGAGATTTCGA\n+TGTGGACAAAGCCAAACCATATCAATACCTTTCGAGTTCTTCACCATGATTTTTTCAAAT\n+GTTGTTTCTGCTAGTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTTCTTTCTGC\n+TCTCTCTGGATATTTTCTATTGATTTCTATATGAGACCATCAGTTTATTTGTGTAGTATC\n+CAGGTGGTTTTTAAACCTATGTAATTACTTCTTGATTTAGCAATTCAACAAAGTTCATTT\n+TATTATTTTTATGAAACCTAATATCCTGCTGAAATGCTCTGTTTTTTAATCCATTTTGCC\n+CATCTCCACGGTAGTTCATGGTTATTTAAAAGCCCTTGCCTATTAGTTCCAAAATCTGTG\n+TCATTTCTTGAGCTCTATTGACTGTATTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCT\n+TTCTTTCTTTCTTTCTTTCTCTCTTTCTTTCTTTCTTTTTTTGCCATCAGGTACTCTTTT\n+CTGCTTCTTTGCATGTCTGGTAAGTTTTGATTGCATGCAGCATTTGTAGAAATTTTAGCT\n+TATGTTTTCTTCCTCTCATAAACTTTGAGTTGTGTTCTAGCAGGTGGTTAAATCATTGGT\n+AGATCACCCTAACCCTACAGAAGCCTAGTTTTTGCTTCGTTCAGTCAAATCTATTTCAGT\n+TTATTCTTTCTCTTAGGACATCATCCTTCTATCTAAGGAGTATCCTTCAAGGGTTTCATC\n+CTAATGCCTGAGGTGTTCACCAAAGTCTTTCCATTCTGACTGGAACCGAACTCCAACATC\n+TCCTCAGAATTGTGTGATCTCTAAAATGTCCACTCAAATTTCAGCCTCTCTGCCACTGCA\n+CTGTATCTGTCAGGTCTCTAGAATAATGCCTCTGGACACATGCAGCCTAGCAATTCAGCT\n+AACGAACTGAGAGGAATTGCCACACAGACTTCCGGTGCTGCCTCTTGGTACTCACCTCTC\n+TGTCACCTTGCTTACCTCCAGAAACCTTAGTTACTTTATATAGCTCCAAGCTCTTGAGCT\n+ATATGCCCTCTGCTCAGTGAAACTGCAGCTCTCTGCTTATTCTCAACCTCCCAAAACTTC\n+TGCTGAAAAAAATATCCCCTGAGGAAAAATAATCCATGGGAATGGGCTCATTCCATGTGC\n+CTCCAGTTACCCCAAATTGCAGCACTATGTTGGTTATGGTTCAGAAGTAAAAAATGTTTG\n+ATATAGTTTTTCCAGGTTTTATAGCTATTTTATGGTAGAAAGGCAAGTGAGTGCTATTAG\n+CTAATTGTCCAGAACCAGAGTCTCATTTCATAACTGCATAAATCCTTTGCTTATCTTGTG\n+TATTTTTTTAAACAAACCTAAAATGCAGGATTTCTAAGTATTTTCCAGTTCTAGCTGATT\n+TCCTTCATTTTAGATGAAAATCCAAAGGTAAATACTCTTTGGTTTCTGATTTTTGGCATC\n+TTGTAAATAAGCATTGCCTCCAGTTTGGTTCATTCTCAGATCTATTAAGTATCCCATTTA\n+TATTTTCCTCTGAAATATAATTTGATAAATCTGCTGAATGATCGGGCACCAAGGTCAGGA\n+CCAATACCTTATTCAAGCCCAGCATGAATCCACTTACCAAGAAACTGGAGGCAACTCTGT\n+CTAAACTGTAATTTGTTTGATACAAACATGCCATCTACATTTACCTTGTCCATAATGATA\n+ATGGGAAGGTTAGCTGAAATCAGGAAATACTGTATTATGAGTTTAGTGACTATTTACAAG\n+TGGAAATGAATTTAATCTGGTATGATTTATTTTACTAAATTGTAGTTGCTTCCTTTTCTT\n+TTCTCACTAGTCACAAATGATTTATTTCAGTATCTTCTCCAGAACATTGCCAGAGGCCAG\n+TCTCAAACTTAACCATTGTATACATACCAGAATATTTTCATTAAAAATTAATAACTTTTG\n+TCTTTCTCTGAAAACTACATAATCACTACTTGTCCATTCTTTTGGTCCTTGCCTGTTCTT\n+TATGGATCAATATTATCAAAGCTACTCCTGTTTCCACAGGCAAATAACAATTCTATGTAA\n+TGGGAAAGATATTAAATCCGAATTCATGTTCCTCTTACTAGCTATATAATGGACAATTAA\n+ATTATTCCTTTAAATTCCTTTCTCCTTTAGTACACAAGGATAAAATACTCATTTGATTGT\n+TTTAAAGATTAAAGAAGTATCTGAAAGTAACTGTTATATTTTCTTCTGAGAGGTATCCCA\n+ATAAAAAGGCTACAATATTGTTATTATTATTACTATTCTAGTATCCTGGATGCAATTTAC\n+CTAAGCCTAGATATTTTAATTAATTTAAGTAGCCACATGCTTTCTCACTAGCTATTTTCC\n+CAGCATGATCTCAATCTTTTCTACGCAAAGTTTAGTCTCTTCTCTCCTAAAGATTGTTCT\n+ACCTAGAGAAGAATATAGGTTCAGAAAGGAATTCATATACTGGTGTTTCTCTAATCTCTT\n+AGAATTACTTAATTTTTCAAAGAGCTCTATCTTTTCCTATTTATCTTCTTGTTCCAAATA\n+GAATTAAAATCATTTGCTGCCTTTAATATTGTTAAATATTTCATTTCATACTATGCTTCA\n+ATTTCTTGCTTTTTTCTTCTTTTTATCTTCCTCCTTCCTTCCTTTTTCTTTCTTTTCTTC\n+TTTTTCAGTTATCATTGTTATGCTTGTCCTTTCTTGTGAGATTCCTCTGTTATCTTTCCT\n+TATGTGCTTTTTAAACAAAACCTCGAGAGTGCCGTGGGACAGCCTCATTGGTATCTTTTC\n+AAATTTGGTATCTCTCCACTTTTTCCTTACATAGTTAGCTGGCAGTAGTACATAATAACC\n+TTTTCTGTCTCTCTCTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTA\n+GATTTTCATTCCTCTTGAGCTTTAAAAGACTGGCTAGCAATGTTATATCTTTCATTTTAT\n+TTTCTGATTTAAAAAAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT\n+ACGCGCGCGCGCGCGCGCGTGCACGTCAGTGTCTTCTTCATGGATGCTTGTCTTATTTTC\n+TCCCAAGGTGTAACTGTCCAGGGAGGGAAAAGTCAAGTCGTCCTCTATTACACTGCTCTG\n+CAGAAACAGACTCACTAAATGTCAAAAAGTAGATGCATCAGACTGTTCCTTAGAGAAAGG\n+TTTGCCATGGAGTCGTATATTGTAACTGAGCTGAAGTTCACTCATCGATAAGTTGTGCCC\n+AAGGAATCGAATTCCTTCCAGTCCTTCTAAGCAGTCCAGGGAAACCAATTTAAAAGCGAA\n+CACAACAAAACTAACAGACCGGCAAAATCTATCTTTGAAGCGCCGCGGGAGGCACAATTT\n+GGGAACAGGTGAGGCCATGCTGGGTGGGTGAGGCCCCCCTCTCTCCTGCTTGGTGTTCCG\n+CTTTCAGCCAACCCACCCCAGGAGTACCCTGGGATCTCCTCGCCCCCTGCCAGGCGGAGA\n+ACGCGGAGCCCAGCGGGCACGCGGGAATGGAGCTAGGCGCCGGCAGGGCAACTGGGCATG\n+CTCAGAAGCCGGGCAGGTTTTGGTCTCAAGCACGCAGCCTGTGCATTACACCAGCTCTCT\n+CAGTCCGGGGAGGAGGAGGAGCAGGAGGAACGCGAGGAGGAAGGAGAGGAGGAGCGGCCA\n+GCAGTAGCCACGACCGCCACCACCAGGCAGAGGAAGAGTTCGTGGGGAGGAAAAGACCTC\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/fn3.hmm
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/fn3.hmm Sat Jun 25 15:07:32 2016 -0400
[
b'@@ -0,0 +1,285 @@\n+HMMER3/f [3.1 | February 2013]\n+NAME  fn3\n+ACC   PF00041.13\n+DESC  Fibronectin type III domain\n+LENG  86\n+ALPH  amino\n+RF    no\n+MM    no\n+CONS  yes\n+CS    yes\n+MAP   yes\n+DATE  Fri Feb 15 06:04:13 2013\n+NSEQ  106\n+EFFN  11.415833\n+CKSUM 3564431818\n+GA    8.00 7.20\n+TC    8.00 7.20\n+NC    7.90 7.90\n+STATS LOCAL MSV       -9.4043  0.71847\n+STATS LOCAL VITERBI   -9.7737  0.71847\n+STATS LOCAL FORWARD   -3.8341  0.71847\n+HMM          A        C        D        E        F        G        H        I        K        L        M        N        P        Q        R        S        T        V        W        Y   \n+            m->m     m->i     m->d     i->m     i->i     d->m     d->d\n+  COMPO   2.70330  4.91262  3.03272  2.64079  3.60307  2.84344  3.74204  3.07942  2.79841  2.65364  4.14864  2.95826  2.87120  3.02176  2.96125  2.44783  2.59757  2.57680  4.02726  3.21526\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.00338  6.08833  6.81068  0.61958  0.77255  0.00000        *\n+      1   3.16986  5.21447  4.52134  3.29953  4.34285  4.18764  4.30886  3.35801  3.70246  2.11675  4.32057  4.32984  0.76706  3.91880  4.22437  3.23552  3.21670  2.88223  5.80355  3.93889      1 p - - -\n+          2.68629  4.42236  2.77530  2.73088  3.46365  2.40512  3.72505  3.29365  2.67737  2.69316  4.24701  2.90358  2.73734  3.18157  2.89812  2.37898  2.77517  2.98515  4.58488  3.61514\n+          0.09796  2.38361  6.81068  0.10064  2.34607  0.48576  0.95510\n+      2   2.70230  5.97353  2.24744  2.62947  5.31433  2.60356  4.43584  4.79731  3.17221  2.95090  5.01531  3.26630  2.09873  3.30219  3.34190  1.45782  3.14099  3.57507  6.40877  4.25623      3 s - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.00338  6.08833  6.81068  0.61958  0.77255  0.48576  0.95510\n+      3   1.38116  5.98285  3.50784  2.54546  5.32790  3.48945  4.43311  4.81385  2.38773  3.98773  5.02352  3.27895  1.92260  2.69012  2.96119  2.64228  3.29228  3.29618  6.41555  4.20553      4 a - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.00338  6.08833  6.81068  0.61958  0.77255  0.48576  0.95510\n+      4   3.32856  5.10403  4.47046  4.60386  4.23079  4.75438  5.09647  2.69918  4.46632  2.97102  4.23502  4.77984  0.63388  4.68581  3.76781  4.05413  3.46306  2.04533  5.75329  4.56372      5 P - - -\n+          2.68616  4.42236  2.77530  2.73134  3.46365  2.40523  3.72505  3.29295  2.67751  2.69303  4.24634  2.90357  2.73739  3.18157  2.89783  2.37897  2.77530  2.98529  4.58488  3.61514\n+          0.09682  2.39494  6.81068  0.10162  2.33687  0.48576  0.95510\n+      5   2.95325  4.65976  3.57762  2.20709  3.14816  2.51487  3.41109  4.78902  2.65862  3.19599  4.41042  3.45032  3.44719  2.43205  2.26492  2.25400  2.23196  3.66828  4.80003  4.52485      7 e - - C\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.01246  6.08833  4.59386  0.61958  0.77255  0.48576  0.95510\n+      6   2.74215  5.97618  2.19482  2.69150  4.58171  2.33553  3.83525  3.28222  2.95080  3.32698  5.01691  1.45822  3.52462  2.79670  2.90942  3.13467  3.27956  4.36668  6.40902  3.92307      8 n - - E\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.00341  6.07928  6.80162  0.61958  0.77255  0.44282  1.02784\n+      7   3.32507  4.98102  3.78072 '..b'.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.00992  6.08833  4.87890  0.61958  0.77255  0.48576  0.95510\n+     79   2.39836  4.69624  2.57939  2.56364  4.72011  1.55094  3.74815  4.26504  2.61409  4.28517  5.02018  2.82673  4.26340  2.69971  2.87382  2.73983  2.53993  3.07568  6.41202  5.00074    110 g - - T\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.00340  6.08180  6.80415  0.61958  0.77255  0.45398  1.00812\n+     80   2.22211  4.94595  2.69424  2.44928  4.84552  2.32005  3.06335  2.95704  2.33976  3.55821  4.09648  2.87488  4.09930  2.85656  2.97877  3.08279  3.07714  2.39346  6.40553  4.01548    111 a - - T\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.38398  6.08833  1.15015  0.61958  0.77255  0.48576  0.95510\n+     81   2.96920  5.43248  3.46409  2.76236  3.93019  1.02513  4.29951  4.07917  3.10833  3.39330  4.50784  3.40559  4.48149  3.45547  3.56956  2.50552  2.39680  3.76237  5.94228  3.01765    112 g - - E\n+          2.68652  4.42259  2.77488  2.73144  3.46170  2.40466  3.72529  3.29388  2.67703  2.69373  4.24724  2.90335  2.73774  3.18162  2.89801  2.37895  2.77529  2.98552  4.58511  3.61537\n+          0.29928  1.35852  6.43163  0.48724  0.95274  1.77816  0.18506\n+     82   2.84273  4.18992  3.05053  2.12883  3.36284  2.75189  4.25559  3.03507  2.66396  2.65563  4.59024  2.63081  3.84786  2.76844  3.19058  2.84597  2.82776  2.89016  3.06821  3.41272    117 e - - E\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.00494  5.70928  6.43163  0.61958  0.77255  1.56406  0.23482\n+     83   3.37920  5.61493  3.74277  3.20384  4.92800  1.01625  3.96683  4.35082  2.94708  2.91738  4.72998  3.71516  3.70329  3.52945  3.00683  1.61777  3.61882  4.00263  6.13360  4.80162    118 g - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.00481  5.73459  6.45693  0.61958  0.77255  0.30535  1.33510\n+     84   2.58463  5.93784  3.04102  2.09605  4.57465  2.51630  3.24109  4.26208  2.60545  3.44607  3.62705  3.20484  1.89678  2.68661  2.74662  2.97880  3.02092  3.23569  6.37074  4.50367    119 p - - E\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.00361  6.02233  6.74467  0.61958  0.77255  0.28862  1.38348\n+     85   2.48488  5.72055  3.87501  1.97538  3.04853  3.48010  4.51877  3.51898  2.88839  2.73568  4.42660  3.64380  2.08811  3.48814  2.70856  2.40769  2.92982  4.05679  2.77386  3.43366    120 e - - B\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.00338  6.08833  6.81068  0.61958  0.77255  0.48576  0.95510\n+     86   3.03720  5.94099  3.75455  2.96917  5.26587  2.91682  3.66571  4.11840  2.98472  4.23738  4.98891  3.74380  4.66031  3.40955  3.12788  0.72443  2.46104  4.32115  6.38683  4.99111    121 s - - E\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.00227  6.08723        *  0.61958  0.77255  0.00000        *\n+//\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/fn3.keys
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/fn3.keys Sat Jun 25 15:07:32 2016 -0400
b
@@ -0,0 +1,1 @@
+fn3
b
diff -r 000000000000 -r a6098dd0cb46 test-data/fn3.out
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/fn3.out Sat Jun 25 15:07:32 2016 -0400
[
@@ -0,0 +1,119 @@
+# hmmsearch :: search profile(s) against a sequence database
+# HMMER 3.1 (February 2013); http://hmmer.org/
+# Copyright (C) 2011 Howard Hughes Medical Institute.
+# Freely distributed under the GNU General Public License (GPLv3).
+# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
+# query HMM file:                  fn3.hmm
+# target sequence database:        7LESS_DROME
+# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
+
+Query:       fn3  [M=86]
+Accession:   PF00041.13
+Description: Fibronectin type III domain
+Scores for complete sequences (score includes all domains):
+   --- full sequence ---   --- best 1 domain ---    -#dom-
+    E-value  score  bias    E-value  score  bias    exp  N  Sequence    Description
+    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
+    1.9e-57  178.0   0.4    1.2e-16   47.2   0.9    9.4  9  7LESS_DROME  RecName: Full=Protein sevenless;          EC=2.7
+
+
+Domain annotation for each sequence (and alignments):
+>> 7LESS_DROME  RecName: Full=Protein sevenless;          EC=2.7.10.1;
+   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
+ ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
+   1 ?   -1.3   0.0      0.17      0.17      61      74 ..     396     409 ..     395     411 .. 0.85
+   2 !   40.7   0.0   1.3e-14   1.3e-14       2      84 ..     439     520 ..     437     521 .. 0.95
+   3 !   14.4   0.0     2e-06     2e-06      13      85 ..     836     913 ..     826     914 .. 0.73
+   4 !    5.1   0.0    0.0016    0.0016      10      36 ..    1209    1235 ..    1203    1259 .. 0.82
+   5 !   24.3   0.0   1.7e-09   1.7e-09      14      80 ..    1313    1380 ..    1304    1386 .. 0.82
+   6 ?    0.0   0.0     0.063     0.063      58      72 ..    1754    1768 ..    1739    1769 .. 0.89
+   7 !   47.2   0.9   1.2e-16   1.2e-16       1      85 [.    1799    1890 ..    1799    1891 .. 0.91
+   8 !   17.8   0.0   1.8e-07   1.8e-07       6      74 ..    1904    1966 ..    1901    1976 .. 0.90
+   9 !   12.8   0.0   6.6e-06   6.6e-06       1      86 []    1993    2107 ..    1993    2107 .. 0.89
+
+  Alignments for each domain:
+  == domain 1  score: -1.3 bits;  conditional E-value: 0.17
+                  EES--TT-EEEEEE CS
+          fn3  61 ltgLepgteYefrV 74 
+                  l+ L p+t+Y+fr 
+  7LESS_DROME 396 LEALIPYTQYRFRF 409
+                  67899*******95 PP
+
+  == domain 2  score: 40.7 bits;  conditional E-value: 1.3e-14
+                  ---CEEEEEEECTTEEEEEEE--S--SS--SEEEEEEEETTTCCGCEEEEEETTTSEEEEES--TT-EEEEEEEEEETTEE-E CS
+          fn3   2 saPenlsvsevtstsltlsWsppkdgggpitgYeveyqekgegeewqevtvprtttsvtltgLepgteYefrVqavngagegp 84 
+                  saP   ++ +  ++ l ++W p +  +gpi+gY++++++++++  + e+ vp+   s+ +++L++gt+Y++ +  +n++gegp
+  7LESS_DROME 439 SAPVIEHLMGLDDSHLAVHWHPGRFTNGPIEGYRLRLSSSEGNA-TSEQLVPAGRGSYIFSQLQAGTNYTLALSMINKQGEGP 520
+                  78999999999*****************************9998.**********************************9997 PP
+
+  == domain 3  score: 14.4 bits;  conditional E-value: 2e-06
+                  CTTEEEEEEE--S.--SS--S.....EEEEEEEETTTCCGCEEEEEETTTSEEEEES--TT-EEEEEEEEEETTE.E-EB CS
+          fn3  13 tstsltlsWsppk.dgggpit.....gYeveyqekgegeewqevtvprtttsvtltgLepgteYefrVqavngag.egpe 85 
+                  ++  + +sW++p+ ++ +  +     +Ye+e+ ++ ++++   +++ ++   + l+ L+p+  Y++rV+a+n +g  g++
+  7LESS_DROME 836 GAQAAKISWKEPErNPYQSADaarswSYELEVLDVASQSAFSIRNIRGPI--FGLQRLQPDNLYQLRVRAINVDGePGEW 913
+                  56677889999987443333223333899999999999955555566666..**********************965655 PP
+
+  == domain 4  score: 5.1 bits;  conditional E-value: 0.0016
+                   EEECTTEEEEEEE--S--SS--SEEEE CS
+          fn3   10 sevtstsltlsWsppkdgggpitgYev 36  
+                   ++   + ++++W+p+++gg + ++Y++
+  7LESS_DROME 1209 DDGHWDDFHVRWQPSTSGGNHSVSYRL 1235
+                   555678999*******99999999997 PP
+
+  == domain 5  score: 24.3 bits;  conditional E-value: 1.7e-09
+                   TTEEEEEEE--S...--SS--SEEEEEEEETTTCCGCEEEEEETTTSEEEEES--TT-EEEEEEEEEETT CS
+          fn3   14 stsltlsWsppk...dgggpitgYeveyqekgegeewqevtvprtttsvtltgLepgteYefrVqavnga 80  
+                   + s++l+W++p+   +   + + Y + ++   ++  + e ++  ++ ++ +++L+p+++Y+f+V+a+ +a
+  7LESS_DROME 1313 NVSAVLRWDAPEqgqEAPMQALEYHISCWVG-SEL-HEELRLNQSALEARVEHLQPDQTYHFQVEARVAA 1380
+                   5689********76556667899******55.665.688888888888*****************98665 PP
+
+  == domain 6  score: 0.0 bits;  conditional E-value: 0.063
+                   EEEEES--TT-EEEE CS
+          fn3   58 svtltgLepgteYef 72  
+                   s++lt+L p t+Y++
+  7LESS_DROME 1754 SLNLTDLLPFTRYRV 1768
+                   799**********98 PP
+
+  == domain 7  score: 47.2 bits;  conditional E-value: 1.2e-16
+                   ----CEEEEEEECTTEEEEEEE--S--SS--SEEEEEEEETTTCC.......GCEEEEEETTTSEEEEES--TT-EEEEEEEEEETTEE-EB CS
+          fn3    1 psaPenlsvsevtstsltlsWsppkdgggpitgYeveyqekgege.......ewqevtvprtttsvtltgLepgteYefrVqavngagegpe 85  
+                   ps+P+n+sv+  ++++l++sW pp++ +++ ++Y++++q++ +ge       ++ + ++ +t+ ++ ltg++pg+ Y+++Vqa+ + +++ +
+  7LESS_DROME 1799 PSPPRNFSVRVLSPRELEVSWLPPEQLRSESVYYTLHWQQELDGEnvqdrreWEAHERRLETAGTHRLTGIKPGSGYSLWVQAHATPTKSNS 1890
+                   9*************************************99989998****97777777777777*******************988776665 PP
+
+  == domain 8  score: 17.8 bits;  conditional E-value: 1.8e-07
+                   EEEEEEECTTEEEEEEE--S--SS--SEEEEEEEETTTCCGCEEEEEETTTSEEEEES--TT-EEEEEE CS
+          fn3    6 nlsvsevtstsltlsWsppkdgggpitgYeveyqekgegeewqevtvprtttsvtltgLepgteYefrV 74  
+                   +l++ e ++ sl+l+W       +p+ + ++e++++ e+    +++v +++t ++++ L+p t+Y+ r+
+  7LESS_DROME 1904 ELQLLELGPYSLSLTWAGT---PDPLGSLQLECRSSAEQ---LRRNVAGNHTKMVVEPLQPRTRYQCRL 1966
+                   5788899************...8***********88555...79**********************986 PP
+
+  == domain 9  score: 12.8 bits;  conditional E-value: 6.6e-06
+                   ----CEEEEEEECTTEEEEEEE--S--SS--SEEEEEEEETTTCC...........................GCEEEEEETTTS.EEEEES--TT- CS
+          fn3    1 psaPenlsvsevtstsltlsWsppkdgggpitgYeveyqekgege...........................ewqevtvprttt.svtltgLepgt 68  
+                   ps+P+ ++++ + +  ++++W++ + +g+pi  Y++e  + ++                             e+q+ +  +tt+ s+ ++ L  ++
+  7LESS_DROME 1993 PSQPGKPQLEHIAEEVFRVTWTAARGNGAPIALYNLEALQARSDIrrrrrrrrrnsggsleqlpwaeepvvvEDQWLDFCNTTElSCIVKSLHSSR 2088
+                   89***********************9************7775554799999999999999999999999999999999999999999999999999 PP
+
+                   EEEEEEEEEETTE.E-EBE CS
+          fn3   69 eYefrVqavngag.egpes 86  
+                      frV+a++ +  +gp+s
+  7LESS_DROME 2089 LLLFRVRARSLEHgWGPYS 2107
+                   9999999999554488876 PP
+
+
+
+Internal pipeline statistics summary:
+-------------------------------------
+Query model(s):                              1  (86 nodes)
+Target sequences:                            1  (2554 residues searched)
+Passed MSV filter:                         1  (1); expected 0.0 (0.02)
+Passed bias filter:                        1  (1); expected 0.0 (0.02)
+Passed Vit filter:                         1  (1); expected 0.0 (0.001)
+Passed Fwd filter:                         1  (1); expected 0.0 (1e-05)
+Initial search space (Z):                  1  [actual number of targets]
+Domain search space  (domZ):               1  [number of targets reported over threshold]
+# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01
+# Mc/sec: 21.96
+//
+[ok]
b
diff -r 000000000000 -r a6098dd0cb46 test-data/fn3.sto
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/fn3.sto Sat Jun 25 15:07:32 2016 -0400
[
b'@@ -0,0 +1,497 @@\n+# STOCKHOLM 1.0\n+#=GF ID fn3\n+#=GF AC PF00041.13\n+#=GF DE Fibronectin type III domain\n+#=GF AU Sonnhammer ELL\n+#=GF GA 8.0 7.2\n+#=GF NC 7.9 7.9\n+#=GF TC 8.0 7.2\n+#=GF SE Swissprot_feature_table\n+#=GF TP Domain\n+#=GF BM hmmbuild -FHMM_ls.ann SEED.ann\n+#=GF BM hmmcalibrate --seed 0 HMM_ls\n+#=GF BM hmmbuild -f -FHMM_fs.ann SEED.ann\n+#=GF BM hmmcalibrate --seed 0 HMM_fs\n+#=GF AM byscore\n+#=GF RN [1]\n+#=GF RM 2169613\n+#=GF RT Structural design and molecular evolution of a cytokine receptor\n+#=GF RT superfamily. \n+#=GF RA Bazan JF; \n+#=GF RL PNAS USA 1990;87:6934-6938.\n+#=GF RN [2]\n+#=GF RM 7528812\n+#=GF RT Tracing the spread of fibronectin type III domains in bacterial\n+#=GF RT glycohydrolases. \n+#=GF RA Little E, Bork P, Doolittle R; \n+#=GF RL J Mol Evol 1994;39:631-643.\n+#=GF RC Definition of fibronectin domains \n+#=GF RN [3]\n+#=GF RM 2992939\n+#=GF RT Primary structure of human fibronectin: differential splicing\n+#=GF RT may generate at least 10 polypeptides from a single gene. \n+#=GF RA Kornblihtt AR, Umezawa K, Vibe-Pedersen K, Baralle FE; \n+#=GF RL EMBO J 1985;4:1755-1759.\n+#=GF DR INTERPRO; IPR003961;\n+#=GF DR HOMSTRAD; fn3;\n+#=GF DR SMART; FN3;\n+#=GF DR SCOP; 1ttf; sf;\n+#=GF DR PRINTS; PR00014;\n+#=GF DR PROSITE; PDOC00214;\n+#=GF SQ 106\n+\n+#=GS TIE1_HUMAN/644-729    AC P35590.1\n+#=GS NCAM1_BOVIN/509-597   AC P31836.1\n+#=GS LAR_DROME/417-503     AC P16621.2\n+#=GS NGCA_CHICK/700-794    AC Q03696.2\n+#=GS MPSF_CHICK/499-585    AC Q02173.1\n+#=GS MPSF_CHICK/371-457    AC Q02173.1\n+#=GS MPSF_CHICK/600-684    AC Q02173.1\n+#=GS NRCAM_CHICK/623-709   AC P35331.1\n+#=GS MYPC2_CHICK/631-717   AC P16419.3\n+#=GS MYLK_CHICK/1318-1403  AC P11799.2\n+#=GS CNTN2_CHICK/602-692   AC P28685.1\n+#=GS MPSF_CHICK/699-785    AC Q02173.1\n+#=GS MPSF_CHICK/801-887    AC Q02173.1\n+#=GS MYPC2_CHICK/924-1006  AC P16419.3\n+#=GS LAR_DROME/322-404     AC P16621.2\n+#=GS FAS2_SCHAM/530-616    AC P22648.2\n+#=GS PTP69_DROME/332-425   AC P16620.2\n+#=GS TENA_CHICK/1227-1306  AC P10039.2\n+#=GS TENA_CHICK/1136-1215  AC P10039.2\n+#=GS TENA_HUMAN/1529-1608  AC P24821.2\n+#=GS TENA_CHICK/1045-1124  AC P10039.2\n+#=GS TENA_HUMAN/1255-1335  AC P24821.2\n+#=GS PTPRB_HUMAN/22-103    AC P23467.1\n+#=GS TIE2_HUMAN/639-724    AC Q02763.1\n+#=GS LAR_DROME/515-598     AC P16621.2\n+#=GS FINC_BOVIN/577-660    AC P07589.3\n+#=GS TIE1_HUMAN/446-533    AC P35590.1\n+#=GS PTPRK_MOUSE/290-376   AC P35822.1\n+#=GS TIE2_HUMAN/444-529    AC Q02763.1\n+#=GS TIE2_HUMAN/543-626    AC Q02763.1\n+#=GS 7LESS_DROVI/1917-1997 AC P20806.1\n+#=GS PTPRZ_HUMAN/312-401   AC P23471.3\n+#=GS FAS2_SCHAM/642-735    AC P22648.2\n+#=GS NCAM1_BOVIN/610-691   AC P31836.1\n+#=GS ITB4_HUMAN/1127-1208  AC P16144.4\n+#=GS UFO_HUMAN/327-411     AC P30530.2\n+#=GS KALM_CHICK/543-641    AC P33005.2\n+#=GS PTP10_DROME/958-1044  AC P35992.3\n+#=GS PTP69_DROME/236-321   AC P16620.2\n+#=GS NRG_DROME/917-1007    AC P20241.2\n+#=GS FINC_BOVIN/689-768    AC P07589.3\n+#=GS FINC_BOVIN/780-858    AC P07589.3\n+#=GS IL7RA_HUMAN/129-221   AC P16871.1\n+#=GS PTP10_DROME/405-485   AC P35992.3\n+#=GS FINC_BOVIN/1417-1499  AC P07589.3\n+#=GS FINC_RAT/1266-1346    AC P04937.2\n+#=GS FINC_BOVIN/1327-1406  AC P07589.3\n+#=GS TENA_CHICK/1317-1395  AC P10039.2\n+#=GS FINC_BOVIN/875-955    AC P07589.3\n+#=GS FINC_BOVIN/1511-1590  AC P07589.3\n+#=GS TENA_CHICK/864-945    AC P10039.2\n+#=GS TENA_CHICK/593-671    AC P10039.2\n+#=GS FINC_BOVIN/1142-1225  AC P07589.3\n+#=GS FINC_BOVIN/1693-1771  AC P07589.3\n+#=GS FINC_BOVIN/1236-1316  AC P07589.3\n+#=GS FINC_BOVIN/1601-1680  AC P07589.3\n+#=GS TENA_CHICK/1494-1571  AC P10039.2\n+#=GS TENA_CHICK/956-1033   AC P10039.2\n+#=GS TENA_CHICK/682-767    AC P10039.2\n+#=GS TENA_CHICK/774-853    AC P10039.2\n+#=GS TENA_CHICK/1406-1483  AC P10039.2\n+#=GS FINC_BOVIN/1782-1861  AC P07589.3\n+#=GS PTPRB_HUMAN/1085-1162 AC P23467.1\n+#=GS PTPRB_HUMAN/1173-1250 AC P23467.1\n+#=GS PTPRB_HUMAN/554-632   AC P23467.1\n+#=GS PTPRB_HUMAN/643-725   AC P23467.1\n+#=GS PTPRB_HUMAN/731-808   AC P23467.1\n+#=GS PTPRB_HUMAN/995-1074  AC P23467.1\n'..b'EEE.EEETTE....E----\n+UFO_HUMAN/327-411             TVCVA.AYTAAG....DGPWS\n+KALM_CHICK/543-641            RLEVQ.VLTTGG....EGPAT\n+PTP10_DROME/958-1044          VFKIQ.AKTAIG....FGPER\n+PTP69_DROME/236-321           FLRIV.GKNSIG....NGQPT\n+NRG_DROME/917-1007            RISIT.ATTKMG....EGSEH\n+FINC_BOVIN/689-768            TVNVY.EISEE.......GEQ\n+FINC_BOVIN/780-858            NITIY.AVEEN.......QES\n+IL7RA_HUMAN/129-221           EIKVR.SIPDHYFKGFWSEWS\n+PTP10_DROME/405-485           SLSVQ.AVSKK.......MES\n+FINC_BOVIN/1417-1499          TITVY.AVTGRG....DSPAS\n+FINC_RAT/1266-1346            DISVI.TLING.......GES\n+FINC_BOVIN/1327-1406          VVSIV.ALNSK.......EES\n+TENA_CHICK/1317-1395          NVNII.SVKGF.......EES\n+#=GR TENA_CHICK/1317-1395  SS EEEEE.EEETT.......EE-\n+FINC_BOVIN/875-955            HFKVF.AVNQG.......RES\n+FINC_BOVIN/1511-1590          VVSVY.AQNQN.......GES\n+TENA_CHICK/864-945            GIGVT.AVRQD.......RES\n+TENA_CHICK/593-671            FIRVF.AILKN.......KKS\n+FINC_BOVIN/1142-1225          NVSVY.TVKDD.......KES\n+FINC_BOVIN/1693-1771          KIHLY.TLNDN.......ARS\n+FINC_BOVIN/1236-1316          LVSVS.SVYEQ.......HES\n+FINC_BOVIN/1601-1680          EVSVY.ALKDT.......LTS\n+TENA_CHICK/1494-1571          TVKLQ.ALSRS.......MRS\n+TENA_CHICK/956-1033           TISLV.AEKGR.......HKS\n+TENA_CHICK/682-767            NVSLH.IVKNNTR...GPGLS\n+TENA_CHICK/774-853            EVTLI.SRRGD.......MES\n+TENA_CHICK/1406-1483          TLRVH.AVKDA.......QKS\n+FINC_BOVIN/1782-1861          TIQVI.ALKNN.......QKS\n+PTPRB_HUMAN/1085-1162         KMVIV.THSGE........LS\n+PTPRB_HUMAN/1173-1250         VLWVV.THSGD........LS\n+PTPRB_HUMAN/554-632           SVVVT.TVSGG.......ISS\n+PTPRB_HUMAN/643-725           TVTIT.TRSGKYE...NHSFS\n+PTPRB_HUMAN/731-808           SVTVT.TKSGQ........YE\n+PTPRB_HUMAN/995-1074          KIQIL.TVSGG.......LFS\n+PTPRB_HUMAN/467-543           MATVT.SISGD........LK\n+PTPRB_HUMAN/907-984           QIMIA.SVSGS........LK\n+PTPRB_HUMAN/112-192           NIAIT.AVSGG.......KRS\n+PTPRB_HUMAN/1355-1434         LVSIK.VQSAG.......MTS\n+PTP10_DROME/583-661           TIQVN.TVSFG.......VES\n+PTP10_DROME/312-394           NVIVK.TVSGK.......VTS\n+PTP10_DROME/217-301           NISVQ.TMSED.......EIS\n+PTP10_DROME/123-205           QVQAY.TIYDG.......KES\n+EPHA2_HUMAN/329-420           TFTVE.ARNGV........SG\n+EPHA1_HUMAN/333-431           TFNVE.AQNGVS....GLGSS\n+EPHB2_CHICK/326-422           TFEIQ.AVNGVTD...QSPFS\n+EPHA3_CHICK/325-421           TFEID.AVNGVSD...LSTLS\n+PTP10_DROME/864-944           TFTVV.VRSGTES..SVLRSS\n+PTPRB_HUMAN/1261-1344         QFNVK.TVSGDS....WKTYS\n+TIE1_HUMAN/545-632            QLDVQ.LYHCTL....LGPAS\n+7LESS_DROME/1799-1891         SLWVQ.AHATPT....KSNSS\n+PHB_ALCFA/344-418             SYTVT.AVDPTAG...ESQPS\n+APU_THETY/928-1009            VYAVT.AVDNDGN...ESALS\n+CHIT_STRLI/142-219            SYSVK.ARDTADQ...TGPAS\n+CHIA1_BACCI/465-542           TFTIK.AKDAAGN...LSAAS\n+GUNB_CELFI/651-733            SYVVK.AKDVAGN...VSAAS\n+CHIX_STROI/169-240            AFQVA.AVNGA.......GES\n+APU_THETY/1165-1248           YYKVV.AVDTSY....NRTAS\n+KALM_CHICK/177-269            QFRVA.AVNVHG....TRGFT\n+CNTN1_CHICK/799-884           HIDVS.AFNSAG....YGPPS\n+CNTN2_CHICK/807-896           HVSVR.AYNRAG....AGPPS\n+NRG_DROME/815-905             YARIL.AYNGRF....NGPPS\n+L1CAM_HUMAN/812-907           HLEVQ.AFNGRG....SGPAS\n+LAR_DROME/709-800             SIQVA.ALTRKG....DGDRS\n+PTP99_DROME/171-259           RVIVK.AFTTKN....EGEPS\n+EPHA2_HUMAN/436-519           LVQVQ.ALTQEG....QGAGS\n+LAR_DROME/909-995             IFRVR.AYTKQG....AGPFS\n+NRCAM_CHICK/928-1014          KFYFN.AQTSV......GSGS\n+EPHB2_CHICK/437-521           VFQVR.ARTVAG....YGRYS\n+EPHA4_MOUSE/441-525           VFHVR.ARTAAG....YGDFS\n+ITB4_HUMAN/1220-1310          RYTVK.ARNGAG....WGPER\n+#=GR ITB4_HUMAN/1220-1310  SS EEEEE.EEETTE....E--BE\n+ITB4_HUMAN/1641-1728          KFKVQ.ARTTEG....FGPER\n+ITB4_HUMAN/1528-1612          VFRVR.AQSQEG....WGRER\n+#=GC SS_cons                  EEEEE.EEETTE....E-EBE\n+#=GC seq_cons                 phpVt.Ahsst.......t.S\n+//\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/globins-45-align.sto
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/globins-45-align.sto Sat Jun 25 15:07:32 2016 -0400
b
b'@@ -0,0 +1,95 @@\n+# STOCKHOLM 1.0\n+\n+MYG_ESCGI          .-VLSDAEWQLVLNIWAKVEADVAGHGQDILIRLFKGHPETLEKFDKFKHLKTEAEMKASEDLKKHGNTVLTALGGILKK-KGHHEAELKPLAQSHATKHKIPIKYLEFISDAIIHVLHSRHPGDFGADAQAAMNKALELFRKDIAAKYKelgfqg\n+#=GR MYG_ESCGI  PP ..69****************************************************************************.99******************************************************************7******\n+MYG_HORSE          g--LSDGEWQQVLNVWGKVEADIAGHGQEVLIRLFTGHPETLEKFDKFKHLKTEAEMKASEDLKKHGTVVLTALGGILKK-KGHHEAELKPLAQSHATKHKIPIKYLEFISDAIIHVLHSKHPGNFGADAQGAMTKALELFRNDIAAKYKelgfqg\n+#=GR MYG_HORSE  PP 8..89***************************************************************************.99******************************************************************7******\n+MYG_PROGU          g--LSDGEWQLVLNVWGKVEGDLSGHGQEVLIRLFKGHPETLEKFDKFKHLKAEDEMRASEELKKHGTTVLTALGGILKK-KGQHAAELAPLAQSHATKHKIPVKYLEFISEAIIQVLQSKHPGDFGADAQGAMSKALELFRNDIAAKYKelgfqg\n+#=GR MYG_PROGU  PP 8..89***************************************************************************.99******************************************************************7******\n+MYG_SAISC          g--LSDGEWQLVLNIWGKVEADIPSHGQEVLISLFKGHPETLEKFDKFKHLKSEDEMKASEELKKHGTTVLTALGGILKK-KGQHEAELKPLAQSHATKHKIPVKYLELISDAIVHVLQKKHPGDFGADAQGAMKKALELFRNDMAAKYKelgfqg\n+#=GR MYG_SAISC  PP 8..89***************************************************************************.99******************************************************************7******\n+MYG_LYCPI          g--LSDGEWQIVLNIWGKVETDLAGHGQEVLIRLFKNHPETLDKFDKFKHLKTEDEMKGSEDLKKHGNTVLTALGGILKK-KGHHEAELKPLAQSHATKHKIPVKYLEFISDAIIQVLQNKHSGDFHADTEAAMKKALELFRNDIAAKYKelgfqg\n+#=GR MYG_LYCPI  PP 8..89***************************************************************************.99******************************************************************7******\n+MYG_MOUSE          g--LSDGEWQLVLNVWGKVEADLAGHGQEVLIGLFKTHPETLDKFDKFKNLKSEEDMKGSEDLKKHGCTVLTALGTILKK-KGQHAAEIQPLAQSHATKHKIPVKYLEFISEIIIEVLKKRHSGDFGADAQGAMSKALELFRNDIAAKYKelgfqg\n+#=GR MYG_MOUSE  PP 8..89***************************************************************************.99******************************************************************7******\n+MYG_MUSAN          v------DWEKVNSVWSAVESDLTAIGQNILLRLFEQYPESQNHFPKFKNKS-LGELKDTADIKAQADTVLSALGNIVKK-KGSHSQPVKALAATHITTHKIPPHYFTKITTIAVDVLSEMYPSEMNAQVQAAFSGAFKIICSDIEKEYKaanfqg\n+#=GR MYG_MUSAN  PP 7......89***************************************9877.89*************************.99****************************************************************997******\n+HBA_AILME          .-VLSPADKTNVKATWDKIGGHAGEYGGEALERTFASFPTTKTYFPHF-DLS-----PGSAQVKAHGKKVADALTTAVGHLD-DLPGALSALSDLHAHKLRVDPVNFKLLSHCLLVTLASHHPAEFTPAVHASLDKFFSAVSTVLTSKYR......\n+#=GR HBA_AILME  PP ..69********************************************.9**.....9***********************9.******************************************************************7......\n+HBA_PROLO          .-VLSPADKANIKATWDKIGGHAGEYGGEALERTFASFPTTKTYFPHF-DLS-----PGSAQVKAHGKKVADALTLAVGHLD-DLPGALSALSDLHAYKLRVDPVNFKLLSHCLLVTLACHHPAEFTPAVHASLDKFFTSVSTVLTSKYR......\n+#=GR HBA_PROLO  PP ..69********************************************.9**.....9***********************9.******************************************************************7......\n+HBA_PAGLA          .-VLSSADKNNIKATWDKIGSHAGEYGAEALERTFISFPTTKTYFPHF-DLS-----HGSAQVKAHGKKVADALTLAVGHLE-DLPNALSALSDLHAYKLRVDPVNFKLLSHCLLVTLACHHPAEFTPAVHSALDKFFSAVSTVLTSKYR......\n+#=GR HBA_PAGLA  PP ..69********************************************.***.....***********************98.9*****************************************************************7......\n+HBA_MACFA          .-VLSPADKTNVKAAWGKVGGHAGEYGAEALERMFLSFPTTKTYFPHF-DLS-----HGSAQVKGHGKKVADALTLAVGHVD-DMPQALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR......\n+#=GR HBA_MACFA  PP ..69********************************************.***.....************************9.******************************************************************7......\n+HBA_MACSI          .-VLSPADKTNVKDAWGKVGGHAGEYGAEALERMFLSFPTTKTYFPHF-'..b'**************************.******************************************************************7......\n+HBB_URSMA          .VHLTGEEKSLVTGLWGKV--NVDEVGGEALGRLLVVYPWTQRFFDSFGDLSSADAIMNNPKVKAHGKKVLNSFSDGLKNLD-NLKGTFAKLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH......\n+#=GR HBB_URSMA  PP .689***************..*************************************************************.******************************************************************7......\n+HBB_RABIT          .VHLSSEEKSAVTALWGKV--NVEEVGGEALGRLLVVYPWTQRFFESFGDLSSANAVMNNPKVKAHGKKVLAAFSEGLSHLD-NLKGTFAKLSELHCDKLHVDPENFRLLGNVLVIVLSHHFGKEFTPQVQAAYQKVVAGVANALAHKYH......\n+#=GR HBB_RABIT  PP .69****************..*************************************************************.******************************************************************7......\n+HBB_TUPGL          .VHLSGEEKAAVTGLWGKV--DLEKVGGQSLGSLLIVYPWTQRFFDSFGDLSSPSAVMSNPKVKAHGKKVLTSFSDGLNHLD-NLKGTFAKLSELHCDKLHVDPENFRLLGNVLVRVLACNFGPEFTPQVQAAFQKVVAGVANALAHKYH......\n+#=GR HBB_TUPGL  PP .69****************..*************************************************************.******************************************************************7......\n+HBB_TRIIN          .VHLTPEEKALVIGLWAKV--NVKEYGGEALGRLLVVYPWTQRFFEHFGDLSSASAIMNNPKVKAHGEKVFTSFGDGLKHLE-DLKGAFAELSELHCDKLHVDPENFRLLGNVLVCVLARHFGKEFSPEAQAAYQKVVAGVANALAHKYH......\n+#=GR HBB_TRIIN  PP .69****************..***********************************************************98.9*****************************************************************7......\n+HBB_COLLI          v-HWSAEEKQLITSIWGKV--NVADCGAEALARLLIVYPWTQRFFSSFGNLSSATAISGNPNVKAHGKKVLTSFGDAVKNLD-NIKGTFAQLSELHCDKLHVDPENFRLLGDILVIILAAHFGKDFTPECQAAWQKLVRVVAHALARKYH......\n+#=GR HBB_COLLI  PP 5.779**************..*************************************************************.******************************************************************7......\n+HBB_LARRI          v-HWSAEEKQLITGLWGKV--NVADCGAEALARLLIVYPWTQRFFASFGNLSSPTAINGNPMVRAHGKKVLTSFGEAVKNLD-NIKNTFAQLSELHCDKLHVDPENFRLLGDILIIVLAAHFAKDFTPDSQAAWQKLVRVVAHALARKYH......\n+#=GR HBB_LARRI  PP 5.779**************..*************************************************************.******************************************************************7......\n+HBB1_VAREX         v-HWTAEEKQLICSLWGKI--DVGLIGGETLAGLLVIYPWTQRQFSHFGNLSSPTAIAGNPRVKAHGKKVLTSFGDAIKNLD-NIKDTFAKLSELHCDKLHVDPTNFKLLGNVLVIVLADHHGKEFTPAHHAAYQKLVNVVSHSLARRYH......\n+#=GR HBB1_VAREX PP 6.6799*************..*************************************************************.******************************************************************7......\n+HBB2_XENTR         v-HWTAEEKATIASVWGKV--DIEQDGHDALSRLLVVYPWTQRYFSSFGNLSNVSAVSGNVKVKAHGNKVLSAVGSAIQHLD-DVKSHLKGLSKSHAEDLHVDPENFKRLADVLVIVLAAKLGSAFTPQVQAVWEKLNATLVAALSHGY-f.....\n+#=GR HBB2_XENTR PP 6.6799*************..************************************************************9.9*************************************************************9988.9.....\n+HBBL_RANCA         v-HWTAEEKAVINSVWQKV--DVEQDGHEALTRLFIVYPWTQRYFSTFGDLSSPAAIAGNPKVHAHGKKILGAIDNAIHNLD-DVKGTLHDLSEEHANELHVDPENFRRLGEVLIVVLGAKLGKAFSPQVQHVWEKFIAVLVDALSHSYH......\n+#=GR HBBL_RANCA PP 6.6799*************..************************************************************9.9*****************************************************************7......\n+HBB2_TRICR         .VHLTAEDRKEIAAILGKV--NVDSLGGQCLARLIVVNPWSRRYFHDFGDLSSCDAICRNPKVLAHGAKVMRSIVEATKHLD-NLREYYADLSVTHSLKFYVDPENFKLFSGIVIVCLALTLQTDFSCHKQLAFEKLMKGVSHALGHGY-......\n+#=GR HBB2_TRICR PP .69****************..*************************************************************.**************************************************************9988.......\n+#=GC PP_cons       .679*****************************************************************************99******************************************************************7......\n+#=GC RF            .xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......\n+//\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/globins-masked.sto
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/globins-masked.sto Sat Jun 25 15:07:32 2016 -0400
b
@@ -0,0 +1,13 @@
+# STOCKHOLM 1.0
+
+#=GS HBB_HUMAN  WT 0.91
+#=GS HBA_HUMAN  WT 0.82
+#=GS MYG_PHYCA  WT 1.13
+#=GS GLB5_PETMA WT 1.14
+
+HBB_HUMAN  --------VHLTPEEKSAVTALWGKV----NVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHL---D--NLKGTFATLSELHCDKL--HVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH------
+HBA_HUMAN  ---------VLSPADKTNVKAAWGKVGA--HAGEYGAEALERMFLSFPTTKTYFPHF-DLS-----HGSAQVKGHGKKVADALTNAVAHV---D--DMPNALSALSDLHAHKL--RVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR------
+MYG_PHYCA  ---------VLSEGEWQLVLHVWAKVEA--DVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKK----K-GHHEAELKPLAQSHATKH--KIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGYQG
+GLB5_PETMA PIVDTGSVAPLSAAEKTKIRSAWAPVYS--TYETSGVDILVKFFTSTPAAQEFFPKFKGLTTADQLKKSADVRWHAERIINAVNDAVASM--DDTEKMSMKLRDLSGKHAKSF--QVDPQYFKVLAAVIADTVAAG---------DAGFEKLMSMICILLRSAY-------
+#=GC MM    .................mmmmmmmmmmm...........mmmmmmmmmmm.........................................................................................................................
+//
b
diff -r 000000000000 -r a6098dd0cb46 test-data/globins.domtblout
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/globins.domtblout Sat Jun 25 15:07:32 2016 -0400
[
@@ -0,0 +1,15 @@
+#                                                                            --- full sequence --- -------------- this domain -------------   hmm coord   ali coord   env coord
+# target name        accession   tlen query name           accession   qlen   E-value  score  bias   #  of  c-Evalue  i-Evalue  score  bias  from    to  from    to  from    to  acc description of target
+#------------------- ---------- ----- -------------------- ---------- ----- --------- ------ ----- --- --- --------- --------- ------ ----- ----- ----- ----- ----- ----- ----- ---- ---------------------
+sp|P02185|MYG_PHYCD  -            154 globins4             -            149   1.8e-70  222.7   3.2   1   1     2e-70     2e-70  222.6   3.2     2   149     2   148     1   148 0.99 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2
+sp|P02024|HBB_GORGO  -            147 globins4             -            149   9.2e-69  217.2   0.1   1   1     1e-68     1e-68  217.0   0.1     1   149     2   147     2   147 0.99 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2
+#
+# Program:         hmmsearch
+# Version:         3.1b2 (February 2015)
+# Pipeline mode:   SEARCH
+# Query file:      /tmp/tmpJW6ntL/files/000/dataset_1.dat
+# Target file:     /tmp/tmpJW6ntL/files/000/dataset_2.dat
+# Option settings: hmmsearch --tblout /tmp/tmpJW6ntL/files/000/dataset_4.dat --domtblout /tmp/tmpJW6ntL/files/000/dataset_5.dat --pfamtblout /tmp/tmpJW6ntL/files/000/dataset_6.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 1 /tmp/tmpJW6ntL/files/000/dataset_1.dat /tmp/tmpJW6ntL/files/000/dataset_2.dat 
+# Current dir:     /tmp/tmpJW6ntL/job_working_directory/000/3
+# Date:            Sat Jun 25 19:27:08 2016
+# [ok]
b
diff -r 000000000000 -r a6098dd0cb46 test-data/globins.pfamtblout
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/globins.pfamtblout Sat Jun 25 15:07:32 2016 -0400
[
@@ -0,0 +1,25 @@
+# Sequence scores
+# ---------------
+#
+# name                  bits   E-value   n   exp  bias    description
+# ------------------- ------ --------- --- ----- -----    ---------------------
+sp|P02185|MYG_PHYCD    222.7   1.8e-70   1   1.0   3.2    Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2
+sp|P02024|HBB_GORGO    217.2   9.2e-69   1   1.0   0.1    Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2
+
+# Domain scores
+# -------------
+#
+#  name                 bits   E-value   hit  bias env-st env-en ali-st ali-en hmm-st hmm-en     description
+# ------------------- ------ --------- ----- ----- ------ ------ ------ ------ ------ ------      ---------------------
+sp|P02185|MYG_PHYCD    222.6     2e-70     1   3.2      1    148      2    148      2    149     Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2
+sp|P02024|HBB_GORGO    217.0     1e-68     1   0.1      2    147      2    147      1    149     Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2
+#
+# Program:         hmmsearch
+# Version:         3.1b2 (February 2015)
+# Pipeline mode:   SEARCH
+# Query file:      /tmp/tmpJW6ntL/files/000/dataset_1.dat
+# Target file:     /tmp/tmpJW6ntL/files/000/dataset_2.dat
+# Option settings: hmmsearch --tblout /tmp/tmpJW6ntL/files/000/dataset_4.dat --domtblout /tmp/tmpJW6ntL/files/000/dataset_5.dat --pfamtblout /tmp/tmpJW6ntL/files/000/dataset_6.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 1 /tmp/tmpJW6ntL/files/000/dataset_1.dat /tmp/tmpJW6ntL/files/000/dataset_2.dat 
+# Current dir:     /tmp/tmpJW6ntL/job_working_directory/000/3
+# Date:            Sat Jun 25 19:27:08 2016
+# [ok]
b
diff -r 000000000000 -r a6098dd0cb46 test-data/globins.tblout
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/globins.tblout Sat Jun 25 15:07:32 2016 -0400
[
@@ -0,0 +1,15 @@
+#                                                               --- full sequence ---- --- best 1 domain ---- --- domain number estimation ----
+# target name        accession  query name           accession    E-value  score  bias   E-value  score  bias   exp reg clu  ov env dom rep inc description of target
+#------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ -----   --- --- --- --- --- --- --- --- ---------------------
+sp|P02185|MYG_PHYCD  -          globins4             -            1.8e-70  222.7   3.2     2e-70  222.6   3.2   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2
+sp|P02024|HBB_GORGO  -          globins4             -            9.2e-69  217.2   0.1     1e-68  217.0   0.1   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2
+#
+# Program:         hmmsearch
+# Version:         3.1b2 (February 2015)
+# Pipeline mode:   SEARCH
+# Query file:      /tmp/tmpJW6ntL/files/000/dataset_1.dat
+# Target file:     /tmp/tmpJW6ntL/files/000/dataset_2.dat
+# Option settings: hmmsearch --tblout /tmp/tmpJW6ntL/files/000/dataset_4.dat --domtblout /tmp/tmpJW6ntL/files/000/dataset_5.dat --pfamtblout /tmp/tmpJW6ntL/files/000/dataset_6.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 1 /tmp/tmpJW6ntL/files/000/dataset_1.dat /tmp/tmpJW6ntL/files/000/dataset_2.dat 
+# Current dir:     /tmp/tmpJW6ntL/job_working_directory/000/3
+# Date:            Sat Jun 25 19:27:08 2016
+# [ok]
b
diff -r 000000000000 -r a6098dd0cb46 test-data/globins4-emit-1.sto
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/globins4-emit-1.sto Sat Jun 25 15:07:32 2016 -0400
b
@@ -0,0 +1,4 @@
+>globins4-sample1
+CLDDGAENDNVLTGVLDLNPDEPSEAEPLILILVQSAPTTKAHFQKFVLLTTNMQVEFDT
+EIKAHTTMIIGASRAILSSIVQNRMNYYLLLLAKENHSGKERATRKKTDRECLHILGEVI
+TITLKREFPMDSNPAHSSRDGTFDLLVSLYRKALRNLY
b
diff -r 000000000000 -r a6098dd0cb46 test-data/globins4-emit.sto
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/globins4-emit.sto Sat Jun 25 15:07:32 2016 -0400
b
@@ -0,0 +1,26 @@
+# STOCKHOLM 1.0
+
+globins4-sample1  -.CLD.DgAENDNVL..TGV.LDLNPD...EPSEAEPLILILVQ.SAPTTK.AH...........FQKFVLLTTN.MQVEFDTEI..KAHT.T.MIIGASRAILSSI.VqNRMN.Y.YLLLLAkEnhsgkE.R..ATRKKTDRECLHILGEVITITL..KREFPMDSNPAHssrDGTFDLLVSLYRKALRNL.Y-.....
+globins4-sample2  K.PLS.P.AQKKTIR..SAW.LLPGHS...KNDLGQEALVHLDL.AVPAMQ.TMishmlllylhkFPQFEHLSPNvKKLAYAELM..RVGA.I.TTL--LSKQWDTLeA.DATR.R.IPLEEN.D.....V.H..LQKYGLIRKKLQVISALVAKVI..LAGHPENFGPKV...SSAF----IVFYKG--EI.YK.....
+globins4-sample3  S.MIS.K.RFKVLVE..NLW.LKV-AT...AGDIGSDQLVTFKA.VFTKIY.LT...........FDEFKGEKV-.---HREIAI..KLYTlS.AIAAILNPPLLNL.R.RIYN.H.ELSQLS.A.....L.H..CTQMQSNQEYFLV--NLTVDTI..YETKPTQYREKS...EASENKVTNLVSNALTAN.YR.....
+globins4-sample4  IsTEC.L.EENEAAK..DVRqEHIVSEmglVDVYSQLLGVLMTT.SIPPTElNR...........MKEKRKLMTR.AGMTTSYAI..RMRG.NhVIHEALSSSAGR-.N.--NQcD.DVVQLS.Q.....K.Y..VTKIYVHPQKIEHITRVLVII-..PYE---THAAEE...DANMEKAVLSVRSRIVTK.FD.....
+globins4-sample5  -.LIS.E.ASFPLVQnvEIW.VKVFNH...YAEAGNESLIKIVV.TYPDGS.KL...........NHCF-HGK-A.TTCQAANDW..KYDK.E.TFVSTLRKVLASR.K.TRFI.KgKILTVE.N.....E.H..KNSVSVALMRPKLGSNCT--TL..LEVIPSWAGPYE...ESAADKCIPLCASILTSE.YR.....
+globins4-sample6  -.ALPgD.TGKQYSH..VCW.AN-HAR...--ESGLDILVRYYL.SLPQTL.NF...........FPKFVDITPK.PIMTNNARL..KEEG.A.AVLDA-MNSLLKI.V.QTIE.N.QFWALK.K.....S.F..AHALHVD-KIYKMLNELLIVIV..AAMEPEHDRPHA...DTAMYKVLQKLRKQLGEGrSLiygfp
+globins4-sample7  P.KFH.N.STKGEVE..RSY.VKVVSK...VDNEGMEYLKDFLSfSRPHAQ.GK...........FGMLKSLQTL.PGLH-VESC..TTME.I.EVLQNLSTPVTGL.D.SQKG.N.EIKELC.R.....V.HldRRTAHVADETFKTYNNSTILRVaqKVHTMRRFDFAA...ADALESFLSYVPCLIEAQ.YQ.....
+globins4-sample8  V.ALS.K.MEQTRVK..ALY.YQV---...SARSGAQALAEMLVrAHPDSR.ML...........FNQAEVIQTR.LTLAENAQI.qRGWG.K.MVVKADSKNMTRV.EgEKHG.M.EPKASA.R.....N.H..IPRENVINGFFKLSALKVVKTV..DVELARGITFSG...NAPVCPYFKGFAAVLSEP.YE.....
+globins4-sample9  A.PLN.A.PGWQDVE..-IW.EYV---...-FHRTIRILRNLLK.EIPWER.RH...........FIKTSTVCLP.IICMGNAKLpwRDGG.T.QGRRALNPSVKQC.QfAKTS.G.SLRQCY.D.....R.QhvAIKDRVLINYFQIVGDLVVDYV..DVKLPQDFNPNL...EADIDRRLFISQRSLNCK.W-.....
+globins4-sample10 -.TLE.M.QLRTDLS..NVA.VKSLAD...LE-VGLEKLMKLYN.SAKLLH.ALr.........cFEPTTKIVTA.SAPKGLRFV..KHQG.T.KVMTAINQAFADM.E.TNYE.Q.KYQSLR.E.....KyK..IEELSIDPRNFQLLAGRVVVRS..AKPLPILLSRQF...ERVLEEHLHLIGKDLQHK.Y-.....
+#=GC RF           x.xxx.x.xxxxxxx..xxx.xxxxxx...xxxxxxxxxxxxxx.xxxxxx.xx...........xxxxxxxxxx.xxxxxxxxx..xxxx.x.xxxxxxxxxxxxx.x.xxxx.x.xxxxxx.x.....x.x..xxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxx...xxxxxxxxxxxxxxxxxx.xx.....
+
+globins4-sample1  ...
+globins4-sample2  ...
+globins4-sample3  ...
+globins4-sample4  ...
+globins4-sample5  ...
+globins4-sample6  gmp
+globins4-sample7  ...
+globins4-sample8  ...
+globins4-sample9  ...
+globins4-sample10 ...
+#=GC RF           ...
+//
b
diff -r 000000000000 -r a6098dd0cb46 test-data/globins4.hmm
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/globins4.hmm Sat Jun 25 15:07:32 2016 -0400
[
b'@@ -0,0 +1,469 @@\n+HMMER3/f [3.1b1 | May 2013]\n+NAME  globins4\n+LENG  149\n+ALPH  amino\n+RF    no\n+MM    no\n+CONS  yes\n+CS    no\n+MAP   yes\n+DATE  Mon Feb  9 11:39:55 2015\n+NSEQ  4\n+EFFN  0.964844\n+CKSUM 2027839109\n+STATS LOCAL MSV       -9.7726  0.70957\n+STATS LOCAL VITERBI  -10.7883  0.70957\n+STATS LOCAL FORWARD   -4.5789  0.70957\n+HMM          A        C        D        E        F        G        H        I        K        L        M        N        P        Q        R        S        T        V        W        Y   \n+            m->m     m->i     m->d     i->m     i->i     d->m     d->d\n+  COMPO   2.36553  4.52577  2.96709  2.70473  3.20818  3.02239  3.41069  2.90041  2.55332  2.35210  3.67329  3.19812  3.45595  3.16091  3.07934  2.66722  2.85475  2.56965  4.55393  3.62921\n+          2.68640  4.42247  2.77497  2.73145  3.46376  2.40504  3.72516  3.29302  2.67763  2.69377  4.24712  2.90369  2.73719  3.18168  2.89823  2.37879  2.77497  2.98431  4.58499  3.61525\n+          0.57544  1.78073  1.31293  1.75577  0.18968  0.00000        *\n+      1   1.70038  4.17733  3.76164  3.36686  3.72281  3.29583  4.27570  2.40482  3.29230  2.54324  3.63799  3.55099  3.93183  3.61602  3.56580  2.71897  2.84104  1.67328  5.32720  4.10031      9 v - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.03156  3.86736  4.58970  0.61958  0.77255  0.34406  1.23405\n+      2   2.62748  4.47174  3.31917  2.82619  3.63815  3.49607  2.75382  3.03401  2.75280  2.74783  3.65114  3.24714  2.62341  3.12082  3.11124  2.79244  2.89355  1.88003  5.06315  3.77128     10 v - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.02321  4.17053  4.89288  0.61958  0.77255  0.48576  0.95510\n+      3   3.50771  4.88753  4.66754  4.31907  3.27776  4.35743  4.88268  2.50779  4.08449  0.57907  3.22569  4.56607  4.74802  4.37991  4.20749  3.97946  3.79191  2.62059  5.25407  4.04279     11 L - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.02321  4.17053  4.89288  0.61958  0.77255  0.48576  0.95510\n+      4   2.34080  4.28719  3.51550  3.22063  4.37406  3.06195  4.29366  3.74891  3.24370  3.47337  4.31943  3.39310  3.80273  3.56072  3.55390  1.08280  2.00280  3.23325  5.72380  4.49519     12 s - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.02321  4.17053  4.89288  0.61958  0.77255  0.48576  0.95510\n+      5   2.04218  4.87966  2.77126  1.92448  4.32563  3.33660  3.78415  3.73388  2.61886  3.34029  4.16568  2.96714  2.18012  2.94561  3.07633  2.70238  2.96803  3.36068  5.56791  4.21854     13 e - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.02321  4.17053  4.89288  0.61958  0.77255  0.48576  0.95510\n+      6   1.67844  4.79514  2.78469  2.00544  4.34945  2.26719  3.85010  3.76260  2.72087  3.37961  4.20641  2.99947  3.85561  3.02442  3.17766  2.68798  2.96575  3.36703  5.60901  4.27005     14 a - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.02321  4.17053  4.89288  0.61958  0.77255  0.48576  0.95510\n+      7   3.05756  5.63998  1.78612  1.06702  4.93093  3.31407  3.86695  4.45859  2.89031  3.95237  4.80915  2.77798  3.94091  3.03432  3.489'..b'.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.02321  4.17053  4.89288  0.61958  0.77255  0.48576  0.95510\n+    142   2.65037  4.69800  3.11777  2.58559  3.93396  3.48363  3.71066  2.49275  2.05906  2.95516  3.80693  2.50024  3.88815  2.89605  2.88872  2.72907  2.42763  2.99850  5.24239  3.94877    158 k - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.02321  4.17053  4.89288  0.61958  0.77255  0.48576  0.95510\n+    143   2.21701  4.52657  2.45380  2.75014  3.73535  3.53805  3.84294  2.86807  2.75770  2.17002  3.64455  3.21159  3.95457  3.08148  3.16791  2.80094  2.89608  2.24528  5.16549  3.89225    159 l - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.02321  4.17053  4.89288  0.61958  0.77255  0.48576  0.95510\n+    144   3.41438  4.70993  5.04893  4.51836  3.21871  4.71073  5.05993  1.60681  4.34794  0.90468  3.01922  4.76098  4.89446  4.48359  4.45935  4.09339  3.64659  2.14279  5.32906  4.22624    160 l - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.02321  4.17053  4.89288  0.61958  0.77255  0.48576  0.95510\n+    145   1.66341  4.55765  3.29747  2.78822  4.09563  3.34088  3.86205  3.44543  2.60980  3.11452  3.96692  3.19039  3.87148  3.05878  2.16675  2.67137  2.29043  3.09965  5.38848  4.12438    161 a - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.02321  4.17053  4.89288  0.61958  0.77255  0.48576  0.95510\n+    146   1.96741  4.60402  3.09101  2.67267  4.09875  3.30287  2.64764  3.55483  2.68845  3.18630  4.02165  3.11035  3.84730  3.04694  3.09548  1.72418  2.88008  3.18467  5.41006  4.09565    162 s - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.02321  4.17053  4.89288  0.61958  0.77255  0.48576  0.95510\n+    147   2.02427  4.88556  3.14956  2.70898  4.40362  3.45865  3.80224  3.73109  1.30907  3.34916  4.21424  3.15279  3.95761  2.96243  2.65527  2.83485  3.06573  3.38348  5.54009  4.27566    163 k - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.02321  4.17053  4.89288  0.61958  0.77255  0.48576  0.95510\n+    148   3.70647  5.07328  4.29292  4.08736  2.37118  4.18885  3.80078  3.67800  3.93734  3.05218  4.32316  4.11065  4.65987  4.16910  4.05541  3.80923  3.99693  3.56378  4.02310  0.58497    164 Y - - -\n+          2.68618  4.42225  2.77519  2.73123  3.46354  2.40513  3.72494  3.29354  2.67741  2.69355  4.24690  2.90347  2.73739  3.18146  2.89801  2.37887  2.77519  2.98518  4.58477  3.61503\n+          0.19360  4.17053  1.82902  0.61958  0.77255  0.48576  0.95510\n+    149   2.92198  5.11574  3.28049  2.65489  4.47826  3.59727  2.51142  3.88373  1.57593  3.35205  4.19259  3.10178  3.96579  2.72398  1.84611  2.91372  3.10363  3.55066  5.42147  4.18835    165 k - - -\n+          2.68634  4.42241  2.77536  2.73098  3.46370  2.40469  3.72511  3.29370  2.67757  2.69331  4.24706  2.90363  2.73756  3.18097  2.89817  2.37903  2.77536  2.98535  4.58493  3.61418\n+          0.22163  1.61553        *  1.50361  0.25145  0.00000        *\n+//\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/globins4.hmm.bin
b
Binary file test-data/globins4.hmm.bin has changed
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diff -r 000000000000 -r a6098dd0cb46 test-data/globins4.hmm2
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/globins4.hmm2 Sat Jun 25 15:07:32 2016 -0400
[
b'@@ -0,0 +1,463 @@\n+HMMER2.0  [converted from 3.1b2]\n+NAME  globins4\n+LENG  149\n+ALPH  Amino\n+RF    no\n+CS    no\n+MAP   yes\n+NSEQ  4\n+DATE  Mon Feb  9 11:39:55 2015\n+XT       -8455     -4  -1000  -1000  -8455     -4  -8455     -4\n+NULT        -4  -8455\n+NULE       656  -1722     98    419   -333    475  -1125    239    250    947  -1073   -271    -50   -338    114    451    113    430  -2131   -717\n+HMM        A      C      D      E      F      G      H      I      K      L      M      N      P      Q      R      S      T      V      W      Y    \n+         m->m   m->i   m->d   i->m   i->i   d->m   d->d   b->m   m->e\n+         -452      *  -1894\n+     1    1213     17  -1203   -954   -716   -908   -721    613   -677   -294    146   -530  -1300   -557   -936    -51    110   1478  -1232   -876     9\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -46  -5579  -6622   -894  -1115   -496  -1780   -830      *\n+     2    -125   -408   -565   -174   -594  -1197   1474   -294    101   -589    127    -92    587    157   -280   -157     35   1180   -851   -402    10\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+     3   -1395  -1008  -2510  -2328    -74  -2440  -1597    465  -1820   2540    741  -1995  -2478  -1659  -1862  -1870  -1262    112  -1127   -793    11\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+     4     289   -142   -848   -743  -1656   -571   -747  -1326   -607  -1636   -837   -302  -1114   -477   -919   2309   1320   -772  -1805  -1446    12\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+     5     720   -996    226   1127  -1586   -967    -12  -1304    294  -1444   -615    312   1227    410   -230    -28    -73   -956  -1580  -1047    13\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+     6    1244   -874    206   1010  -1620    576   -107  -1345    147  -1501   -674    266  -1190    296   -376     -7    -70   -965  -1639  -1121    14\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+     7    -745  -2093   1647   2364  -2459   -934   -132  -2349    -97  -2327  -1544    585  -1313    282   -826   -363   -621  -1916  -2339  -1579    15\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+     8    -635  -1057   -831   -298   -776  -1494     33  -1068   2270  -1126   -444   -200  -1534    331    530   -531   -393   -888   2804   -311    16\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+     9     -76   -729   -155    138  -1389   -965    -43  -1111    336  -1268   -448    162  -1188   1474   -109    774   1544   -773  -1416   -944    17\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -89'..b'   -307   155\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+   140    -786   -314  -2766  -2294   1397  -2470  -1388   1811  -1947    564    740  -1826  -2354  -1591  -1983  -1500   -590   1931   -993   -645   156\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+   141     737   2273   -756   -307   -898   -955   -210   -561     15   -824    -50   -131  -1206     75    919    739    140   -296  -1087   -707   157\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+   142    -158   -734   -274    173  -1021  -1179     94    487   1102   -888    -98    986  -1237    482     41    -66    707   -434  -1110   -658   158\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+   143     467   -487    684    -64   -734  -1258    -97    -55     94    245    137    -40  -1333    214   -362   -170     31    653   -999   -576   159\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+   144   -1260   -751  -3060  -2615     11  -2949  -1853   1765  -2200   2070   1039  -2276  -2689  -1809  -2225  -2034  -1052    801  -1235  -1058   160\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+   145    1266   -532   -534   -119  -1254   -973   -124   -888    307  -1118   -328    -10  -1213    247   1082     17    905   -579  -1321   -911   161\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+   146     827   -599   -236     48  -1259   -918   1628  -1046    194  -1222   -407    106  -1178    264   -258   1384     54   -702  -1352   -870   162\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+   147     745  -1005   -320     -5  -1699  -1143    -38  -1300   2184  -1457   -685     44  -1338    386    378   -219   -214   -989  -1540  -1129   163\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -     -33  -6017  -7059   -894  -1115   -701  -1378      *      *\n+   148   -1682  -1276  -1970  -1993   1234  -2197    -36  -1223  -1608  -1028   -842  -1338  -2351  -1355  -1642  -1624  -1557  -1249    649   4195   164\n+     -    -210   -336    220    -37   -342    377     73   -669    210   -511   -732    404    423     70     27    439    205   -414   -161   -176\n+     -    -279  -6017  -2639   -894  -1115   -701  -1378      *      *\n+   149    -550  -1337   -509     73  -1806  -1343   1824  -1520   1799  -1461   -654    118  -1349    730   1545   -332   -269  -1230  -1368  -1003   165\n+     -       *      *      *      *      *      *      *      *      *      *      *      *      *      *      *      *      *      *      *      *\n+     -       *      *      *      *      *      *      *      *      0\n+//\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/globins4.out
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/globins4.out Sat Jun 25 15:07:32 2016 -0400
[
b'@@ -0,0 +1,19847 @@\n+# hmmsearch :: search profile(s) against a sequence database\n+# HMMER 3.1 (February 2013); http://hmmer.org/\n+# Copyright (C) 2011 Howard Hughes Medical Institute.\n+# Freely distributed under the GNU General Public License (GPLv3).\n+# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -\n+# query HMM file:                  globins4.hmm\n+# target sequence database:        uniprot_sprot.fasta\n+# per-seq hits tabular output:     globins4.tbl\n+# per-dom hits tabular output:     globins4.domtbl\n+# number of worker threads:        2\n+# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -\n+\n+Query:       globins4  [M=149]\n+Scores for complete sequences (score includes all domains):\n+   --- full sequence ---   --- best 1 domain ---    -#dom-\n+    E-value  score  bias    E-value  score  bias    exp  N  Sequence              Description\n+    ------- ------ -----    ------- ------ -----   ---- --  --------              -----------\n+    6.5e-65  222.7   3.2    7.2e-65  222.6   3.2    1.0  1  sp|P02185|MYG_PHYMC    Myoglobin OS=Physeter macrocephalus GN\n+    3.3e-63  217.2   0.1    3.7e-63  217.0   0.1    1.0  1  sp|P02024|HBB_GORGO    Hemoglobin subunit beta OS=Gorilla gor\n+    4.9e-63  216.6   0.0    5.4e-63  216.5   0.0    1.0  1  sp|P68871|HBB_HUMAN    Hemoglobin subunit beta OS=Homo sapien\n+    4.9e-63  216.6   0.0    5.4e-63  216.5   0.0    1.0  1  sp|P68872|HBB_PANPA    Hemoglobin subunit beta OS=Pan paniscu\n+    4.9e-63  216.6   0.0    5.4e-63  216.5   0.0    1.0  1  sp|P68873|HBB_PANTR    Hemoglobin subunit beta OS=Pan troglod\n+      7e-63  216.1   3.0    7.7e-63  216.0   3.0    1.0  1  sp|P02177|MYG_ESCGI    Myoglobin OS=Eschrichtius gibbosus GN=\n+      7e-63  216.1   3.0    7.7e-63  216.0   3.0    1.0  1  sp|Q0KIY1|MYG_BALBO    Myoglobin OS=Balaenoptera borealis GN=\n+      7e-63  216.1   3.0    7.7e-63  216.0   3.0    1.0  1  sp|Q0KIY2|MYG_BALED    Myoglobin OS=Balaenoptera edeni GN=MB \n+    7.6e-63  216.0   0.1    8.4e-63  215.9   0.1    1.0  1  sp|P02025|HBB_HYLLA    Hemoglobin subunit beta OS=Hylobates l\n+    1.1e-62  215.6   0.2    1.2e-62  215.4   0.2    1.0  1  sp|P02033|HBB_PILBA    Hemoglobin subunit beta OS=Piliocolobu\n+    1.1e-62  215.5   3.7    1.2e-62  215.3   3.7    1.0  1  sp|P02178|MYG_MEGNO    Myoglobin OS=Megaptera novaeangliae GN\n+    2.3e-62  214.4   1.8    2.6e-62  214.3   1.8    1.0  1  sp|P02174|MYG_GLOME    Myoglobin OS=Globicephala melas GN=MB \n+    4.2e-62  213.6   1.8    4.6e-62  213.5   1.8    1.0  1  sp|P02173|MYG_ORCOR    Myoglobin OS=Orcinus orca GN=MB PE=1 S\n+    4.6e-62  213.5   4.2    5.1e-62  213.3   4.2    1.0  1  sp|P02179|MYG_BALAC    Myoglobin OS=Balaenoptera acutorostrat\n+    4.9e-62  213.4   1.3    5.5e-62  213.2   1.3    1.0  1  sp|P02181|MYG_INIGE    Myoglobin OS=Inia geoffrensis GN=MB PE\n+    5.3e-62  213.3   0.1    5.9e-62  213.1   0.1    1.0  1  sp|P02028|HBB_CHLAE    Hemoglobin subunit beta OS=Chlorocebus\n+    5.6e-62  213.2   4.2    6.3e-62  213.0   4.2    1.0  1  sp|P02184|MYG_KOGSI    Myoglobin OS=Kogia sima GN=MB PE=1 SV=\n+    5.6e-62  213.2   4.2    6.3e-62  213.0   4.2    1.0  1  sp|Q0KIY5|MYG_KOGBR    Myoglobin OS=Kogia breviceps GN=MB PE=\n+    7.1e-62  212.9   0.2    7.9e-62  212.7   0.2    1.0  1  sp|P02040|HBB_CEBAL    Hemoglobin subunit beta OS=Cebus albif\n+      1e-61  212.3   1.8    1.2e-61  212.2   1.8    1.0  1  sp|Q0KIY3|MYG_PENEL    Myoglobin OS=Peponocephala electra GN=\n+    1.1e-61  212.3   0.1    1.2e-61  212.1   0.1    1.0  1  sp|Q6WN25|HBB_LAGLA    Hemoglobin subunit beta OS=Lagothrix l\n+    1.1e-61  212.3   2.0    1.2e-61  212.1   2.0    1.0  1  sp|P68276|MYG_DELDE    Myoglobin OS=Delphinus delphis GN=MB P\n+    1.1e-61  212.3   2.0    1.2e-61  212.1   2.0    1.0  1  sp|P68279|MYG_TURTR    Myoglobin OS=Tursiops truncatus GN=MB \n+    1.1e-61  212.3   2.0    1.2e-61  212.1   2.0    1.0  1  sp|Q0KIY7|MYG1_STEAT   Myoglobin-1 OS=Stenella attenuata GN=M\n+    1.1e-61  212.2   0.1    1.3e-61  212.1   0.1    1.'..b'-- --------- ------- -------    ------- -------    ------- -------    ----\n+   1 ?   11.2   0.0     0.021        10      51     100 ..      50      98 ..      43     106 .. 0.92\n+\n+  Alignments for each domain:\n+  == domain 1  score: 11.2 bits;  conditional E-value: 0.021\n+               globins4  51 stedelkksadvkkHgkkvldAlsdalakldekleaklkdLselHakklk 100\n+                            +te++lk  +dv  H + + dA+++  +k+d  ++ k++++   Ha++l \n+  sp|B0FZN9|SCML1_PONPY  50 NTEEQLKTVNDVLIHCQVIYDAMQNLDKKID-VIRRKVSKIQRFHARSLW 98 \n+                            79****************************9.99************9875 PP\n+\n+>> sp|Q9UN30|SCML1_HUMAN  Sex comb on midleg-like protein 1 OS=Homo sapiens GN=SCML1 PE=1 SV=2\n+   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc\n+ ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----\n+   1 ?   11.8   0.1     0.013       6.3      51     100 ..      50      98 ..      44     117 .. 0.92\n+\n+  Alignments for each domain:\n+  == domain 1  score: 11.8 bits;  conditional E-value: 0.013\n+               globins4  51 stedelkksadvkkHgkkvldAlsdalakldekleaklkdLselHakklk 100\n+                            +te++lk  +dv  H + + dAl++  +k+d  ++ k++++   Ha++l \n+  sp|Q9UN30|SCML1_HUMAN  50 NTEEQLKTVDDVLIHCQVIYDALQNLDKKID-VIRRKVSKIQRFHARSLW 98 \n+                            79****************************9.99************9985 PP\n+\n+>> sp|B8FUJ0|SYGB_DESHD  Glycine--tRNA ligase beta subunit OS=Desulfitobacterium hafniense (strain DCB-2 / DSM 10664) GN\n+   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc\n+ ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----\n+   1 ?    9.1   0.0     0.091        44      86     134 ..      24      76 ..      13      81 .. 0.85\n+\n+  Alignments for each domain:\n+  == domain 1  score: 9.1 bits;  conditional E-value: 0.091\n+              globins4  86 aklkdLselHakklkvdpkyfklls.....evlvdvlaarlpkeftadvqaale 134\n+                           ++l++ +++++++l++d + +k+ +     +vl++ la++  ++fta+v++   \n+  sp|B8FUJ0|SYGB_DESHD  24 NQLREQAQKYCQELRLDYQDLKVYTtprrfAVLIQGLAEK-QTDFTAEVKGPAV 76 \n+                           789999*****************984555569******99.99****9998655 PP\n+\n+>> sp|Q498L9|KI15B_XENLA  Kinesin-like protein KIF15-B OS=Xenopus laevis GN=kif15-b PE=1 SV=1\n+   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc\n+ ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----\n+   1 ?   10.1   0.8     0.044        22      38     100 ..     600     661 ..     587     674 .. 0.86\n+\n+  Alignments for each domain:\n+  == domain 1  score: 10.1 bits;  conditional E-value: 0.044\n+               globins4  38 PatqefFekFkdLstedelkksadvkkHgkkvldAlsdalakldekleaklkdLselHakklk 100\n+                             ++++ +e+Fk+L+ + ++++  +++   k   + l+++l  ++e+ + ++++L   Ha+  k\n+  sp|Q498L9|KI15B_XENLA 600 ATSKQEYEEFKELTKKKQVEQESELQSLMK-SNQHLENILDAIKENKRHEVSQLNRMHAETIK 661\n+                            467889*******************98765.57889999999999**************9765 PP\n+\n+\n+\n+Internal pipeline statistics summary:\n+-------------------------------------\n+Query model(s):                              1  (149 nodes)\n+Target sequences:                       539165  (191456931 residues searched)\n+Passed MSV filter:                     20801  (0.03858); expected 10783.3 (0.02)\n+Passed bias filter:                    17061  (0.0316434); expected 10783.3 (0.02)\n+Passed Vit filter:                      2321  (0.0043048); expected 539.2 (0.001)\n+Passed Fwd filter:                      1109  (0.00205688); expected 5.4 (1e-05)\n+Initial search space (Z):             539165  [actual number of targets]\n+Domain search space  (domZ):            1108  [number of targets reported over threshold]\n+# CPU time: 6.50u 0.11s 00:00:06.61 Elapsed: 00:00:02.59\n+# Mc/sec: 11014.32\n+//\n+[ok]\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/globins4.sto
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/globins4.sto Sat Jun 25 15:07:32 2016 -0400
b
@@ -0,0 +1,18 @@
+# STOCKHOLM 1.0
+
+HBB_HUMAN   ........VHLTPEEKSAVTALWGKV....NVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVL
+HBA_HUMAN   .........VLSPADKTNVKAAWGKVGA..HAGEYGAEALERMFLSFPTTKTYFPHF.DLS.....HGSAQVKGHGKKVA
+MYG_PHYCA   .........VLSEGEWQLVLHVWAKVEA..DVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTVL
+GLB5_PETMA  PIVDTGSVAPLSAAEKTKIRSAWAPVYS..TYETSGVDILVKFFTSTPAAQEFFPKFKGLTTADQLKKSADVRWHAERII
+
+HBB_HUMAN   GAFSDGLAHL...D..NLKGTFATLSELHCDKL..HVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANAL
+HBA_HUMAN   DALTNAVAHV...D..DMPNALSALSDLHAHKL..RVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVL
+MYG_PHYCA   TALGAILKK....K.GHHEAELKPLAQSHATKH..KIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDI
+GLB5_PETMA  NAVNDAVASM..DDTEKMSMKLRDLSGKHAKSF..QVDPQYFKVLAAVIADTVAAG.........DAGFEKLMSMICILL
+
+HBB_HUMAN   AHKYH......
+HBA_HUMAN   TSKYR......
+MYG_PHYCA   AAKYKELGYQG
+GLB5_PETMA  RSAY.......
+//
+
b
diff -r 000000000000 -r a6098dd0cb46 test-data/globins45.fa
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/globins45.fa Sat Jun 25 15:07:32 2016 -0400
b
@@ -0,0 +1,186 @@
+>MYG_ESCGI 
+VLSDAEWQLVLNIWAKVEADVAGHGQDILIRLFKGHPETLEKFDKFKHLK
+TEAEMKASEDLKKHGNTVLTALGGILKKKGHHEAELKPLAQSHATKHKIP
+IKYLEFISDAIIHVLHSRHPGDFGADAQAAMNKALELFRKDIAAKYKELG
+FQG
+>MYG_HORSE 
+GLSDGEWQQVLNVWGKVEADIAGHGQEVLIRLFTGHPETLEKFDKFKHLK
+TEAEMKASEDLKKHGTVVLTALGGILKKKGHHEAELKPLAQSHATKHKIP
+IKYLEFISDAIIHVLHSKHPGNFGADAQGAMTKALELFRNDIAAKYKELG
+FQG
+>MYG_PROGU 
+GLSDGEWQLVLNVWGKVEGDLSGHGQEVLIRLFKGHPETLEKFDKFKHLK
+AEDEMRASEELKKHGTTVLTALGGILKKKGQHAAELAPLAQSHATKHKIP
+VKYLEFISEAIIQVLQSKHPGDFGADAQGAMSKALELFRNDIAAKYKELG
+FQG
+>MYG_SAISC 
+GLSDGEWQLVLNIWGKVEADIPSHGQEVLISLFKGHPETLEKFDKFKHLK
+SEDEMKASEELKKHGTTVLTALGGILKKKGQHEAELKPLAQSHATKHKIP
+VKYLELISDAIVHVLQKKHPGDFGADAQGAMKKALELFRNDMAAKYKELG
+FQG
+>MYG_LYCPI 
+GLSDGEWQIVLNIWGKVETDLAGHGQEVLIRLFKNHPETLDKFDKFKHLK
+TEDEMKGSEDLKKHGNTVLTALGGILKKKGHHEAELKPLAQSHATKHKIP
+VKYLEFISDAIIQVLQNKHSGDFHADTEAAMKKALELFRNDIAAKYKELG
+FQG
+>MYG_MOUSE 
+GLSDGEWQLVLNVWGKVEADLAGHGQEVLIGLFKTHPETLDKFDKFKNLK
+SEEDMKGSEDLKKHGCTVLTALGTILKKKGQHAAEIQPLAQSHATKHKIP
+VKYLEFISEIIIEVLKKRHSGDFGADAQGAMSKALELFRNDIAAKYKELG
+FQG
+>MYG_MUSAN 
+VDWEKVNSVWSAVESDLTAIGQNILLRLFEQYPESQNHFPKFKNKSLGEL
+KDTADIKAQADTVLSALGNIVKKKGSHSQPVKALAATHITTHKIPPHYFT
+KITTIAVDVLSEMYPSEMNAQVQAAFSGAFKIICSDIEKEYKAANFQG
+>HBA_AILME 
+VLSPADKTNVKATWDKIGGHAGEYGGEALERTFASFPTTKTYFPHFDLSP
+GSAQVKAHGKKVADALTTAVGHLDDLPGALSALSDLHAHKLRVDPVNFKL
+LSHCLLVTLASHHPAEFTPAVHASLDKFFSAVSTVLTSKYR
+>HBA_PROLO 
+VLSPADKANIKATWDKIGGHAGEYGGEALERTFASFPTTKTYFPHFDLSP
+GSAQVKAHGKKVADALTLAVGHLDDLPGALSALSDLHAYKLRVDPVNFKL
+LSHCLLVTLACHHPAEFTPAVHASLDKFFTSVSTVLTSKYR
+>HBA_PAGLA 
+VLSSADKNNIKATWDKIGSHAGEYGAEALERTFISFPTTKTYFPHFDLSH
+GSAQVKAHGKKVADALTLAVGHLEDLPNALSALSDLHAYKLRVDPVNFKL
+LSHCLLVTLACHHPAEFTPAVHSALDKFFSAVSTVLTSKYR
+>HBA_MACFA 
+VLSPADKTNVKAAWGKVGGHAGEYGAEALERMFLSFPTTKTYFPHFDLSH
+GSAQVKGHGKKVADALTLAVGHVDDMPQALSALSDLHAHKLRVDPVNFKL
+LSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
+>HBA_MACSI 
+VLSPADKTNVKDAWGKVGGHAGEYGAEALERMFLSFPTTKTYFPHFDLSH
+GSAQVKGHGKKVADALTLAVGHVDDMPQALSALSDLHAHKLRVDPVNFKL
+LSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
+>HBA_PONPY 
+VLSPADKTNVKTAWGKVGAHAGDYGAEALERMFLSFPTTKTYFPHFDLSH
+GSAQVKDHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKL
+LSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
+>HBA2_GALCR 
+VLSPTDKSNVKAAWEKVGAHAGDYGAEALERMFLSFPTTKTYFPHFDLSH
+GSTQVKGHGKKVADALTNAVLHVDDMPSALSALSDLHAHKLRVDPVNFKL
+LRHCLLVTLACHHPAEFTPAVHASLDKFMASVSTVLTSKYR
+>HBA_MESAU 
+VLSAKDKTNISEAWGKIGGHAGEYGAEALERMFFVYPTTKTYFPHFDVSH
+GSAQVKGHGKKVADALTNAVGHLDDLPGALSALSDLHAHKLRVDPVNFKL
+LSHCLLVTLANHHPADFTPAVHASLDKFFASVSTVLTSKYR
+>HBA2_BOSMU 
+VLSAADKGNVKAAWGKVGGHAAEYGAEALERMFLSFPTTKTYFPHFDLSH
+GSAQVKGHGAKVAAALTKAVGHLDDLPGALSELSDLHAHKLRVDPVNFKL
+LSHSLLVTLASHLPSDFTPAVHASLDKFLANVSTVLTSKYR
+>HBA_ERIEU 
+VLSATDKANVKTFWGKLGGHGGEYGGEALDRMFQAHPTTKTYFPHFDLNP
+GSAQVKGHGKKVADALTTAVNNLDDVPGALSALSDLHAHKLRVDPVNFKL
+LSHCLLVTLALHHPADFTPAVHASLDKFLATVATVLTSKYR
+>HBA_FRAPO 
+VLSAADKNNVKGIFGKISSHAEDYGAEALERMFITYPSTKTYFPHFDLSH
+GSAQVKGHGKKVVAALIEAANHIDDIAGTLSKLSDLHAHKLRVDPVNFKL
+LGQCFLVVVAIHHPSALTPEVHASLDKFLCAVGNVLTAKYR
+>HBA_PHACO 
+VLSAADKNNVKGIFTKIAGHAEEYGAEALERMFITYPSTKTYFPHFDLSH
+GSAQIKGHGKKVVAALIEAVNHIDDITGTLSKLSDLHAHKLRVDPVNFKL
+LGQCFLVVVAIHHPSALTPEVHASLDKFLCAVGTVLTAKYR
+>HBA_TRIOC 
+VLSANDKTNVKTVFTKITGHAEDYGAETLERMFITYPPTKTYFPHFDLHH
+GSAQIKAHGKKVVGALIEAVNHIDDIAGALSKLSDLHAQKLRVDPVNFKL
+LGQCFLVVVAIHHPSVLTPEVHASLDKFLCAVGNVLSAKYR
+>HBA_ANSSE 
+VLSAADKGNVKTVFGKIGGHAEEYGAETLQRMFQTFPQTKTYFPHFDLQP
+GSAQIKAHGKKVAAALVEAANHIDDIAGALSKLSDLHAQKLRVDPVNFKF
+LGHCFLVVLAIHHPSLLTPEVHASMDKFLCAVATVLTAKYR
+>HBA_COLLI 
+VLSANDKSNVKAVFAKIGGQAGDLGGEALERLFITYPQTKTYFPHFDLSH
+GSAQIKGHGKKVAEALVEAANHIDDIAGALSKLSDLHAQKLRVDPVNFKL
+LGHCFLVVVAVHFPSLLTPEVHASLDKFVLAVGTVLTAKYR
+>HBAD_CHLME 
+MLTADDKKLLTQLWEKVAGHQEEFGSEALQRMFLTYPQTKTYFPHFDLHP
+GSEQVRGHGKKVAAALGNAVKSLDNLSQALSELSNLHAYNLRVDPANFKL
+LAQCFQVVLATHLGKDYSPEMHAAFDKFLSAVAAVLAEKYR
+>HBAD_PASMO 
+MLTAEDKKLIQQIWGKLGGAEEEIGADALWRMFHSYPSTKTYFPHFDLSQ
+GSDQIRGHGKKVVAALSNAIKNLDNLSQALSELSNLHAYNLRVDPVNFKF
+LSQCLQVSLATRLGKEYSPEVHSAVDKFMSAVASVLAEKYR
+>HBAZ_HORSE 
+SLTKAERTMVVSIWGKISMQADAVGTEALQRLFSSYPQTKTYFPHFDLHE
+GSPQLRAHGSKVAAAVGDAVKSIDNVAGALAKLSELHAYILRVDPVNFKF
+LSHCLLVTLASRLPADFTADAHAAWDKFLSIVSSVLTEKYR
+>HBA4_SALIR 
+SLSAKDKANVKAIWGKILPKSDEIGEQALSRMLVVYPQTKAYFSHWASVA
+PGSAPVKKHGITIMNQIDDCVGHMDDLFGFLTKLSELHATKLRVDPTNFK
+ILAHNLIVVIAAYFPAEFTPEIHLSVDKFLQQLALALAEKYR
+>HBB_ORNAN 
+VHLSGGEKSAVTNLWGKVNINELGGEALGRLLVVYPWTQRFFEAFGDLSS
+AGAVMGNPKVKAHGAKVLTSFGDALKNLDDLKGTFAKLSELHCDKLHVDP
+ENFNRLGNVLIVVLARHFSKDFSPEVQAAWQKLVSGVAHALGHKYH
+>HBB_TACAC 
+VHLSGSEKTAVTNLWGHVNVNELGGEALGRLLVVYPWTQRFFESFGDLSS
+ADAVMGNAKVKAHGAKVLTSFGDALKNLDNLKGTFAKLSELHCDKLHVDP
+ENFNRLGNVLVVVLARHFSKEFTPEAQAAWQKLVSGVSHALAHKYH
+>HBE_PONPY 
+VHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSS
+PSAILGNPKVKAHGKKVLTSFGDAIKNMDNLKTTFAKLSELHCDKLHVDP
+ENFKLLGNVMVIILATHFGKEFTPEVQAAWQKLVSAVAIALAHKYH
+>HBB_SPECI 
+VHLSDGEKNAISTAWGKVHAAEVGAEALGRLLVVYPWTQRFFDSFGDLSS
+ASAVMGNAKVKAHGKKVIDSFSNGLKHLDNLKGTFASLSELHCDKLHVDP
+ENFKLLGNMIVIVMAHHLGKDFTPEAQAAFQKVVAGVANALAHKYH
+>HBB_SPETO 
+VHLTDGEKNAISTAWGKVNAAEIGAEALGRLLVVYPWTQRFFDSFGDLSS
+ASAVMGNAKVKAHGKKVIDSFSNGLKHLDNLKGTFASLSELHCDKLHVDP
+ENFKLLGNMIVIVMAHHLGKDFTPEAQAAFQKVVAGVANALSHKYH
+>HBB_EQUHE 
+VQLSGEEKAAVLALWDKVNEEEVGGEALGRLLVVYPWTQRFFDSFGDLSN
+PAAVMGNPKVKAHGKKVLHSFGEGVHHLDNLKGTFAQLSELHCDKLHVDP
+ENFRLLGNVLVVVLARHFGKDFTPELQASYQKVVAGVANALAHKYH
+>HBB_SUNMU 
+VHLSGEEKACVTGLWGKVNEDEVGAEALGRLLVVYPWTQRFFDSFGDLSS
+ASAVMGNPKVKAHGKKVLHSLGEGVANLDNLKGTFAKLSELHCDKLHVDP
+ENFRLLGNVLVVVLASKFGKEFTPPVQAAFQKVVAGVANALAHKYH
+>HBB_CALAR 
+VHLTGEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLST
+PDAVMNNPKVKAHGKKVLGAFSDGLTHLDNLKGTFAHLSELHCDKLHVDP
+ENFRLLGNVLVCVLAHHFGKEFTPVVQAAYQKVVAGVANALAHKYH
+>HBB_MANSP 
+VHLTPEEKTAVTTLWGKVNVDEVGGEALGRLLVVYPWTQRFFDSFGDLSS
+PDAVMGNPKVKAHGKKVLGAFSDGLNHLDNLKGTFAQLSELHCDKLHVDP
+ENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
+>HBB_URSMA 
+VHLTGEEKSLVTGLWGKVNVDEVGGEALGRLLVVYPWTQRFFDSFGDLSS
+ADAIMNNPKVKAHGKKVLNSFSDGLKNLDNLKGTFAKLSELHCDKLHVDP
+ENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
+>HBB_RABIT 
+VHLSSEEKSAVTALWGKVNVEEVGGEALGRLLVVYPWTQRFFESFGDLSS
+ANAVMNNPKVKAHGKKVLAAFSEGLSHLDNLKGTFAKLSELHCDKLHVDP
+ENFRLLGNVLVIVLSHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
+>HBB_TUPGL 
+VHLSGEEKAAVTGLWGKVDLEKVGGQSLGSLLIVYPWTQRFFDSFGDLSS
+PSAVMSNPKVKAHGKKVLTSFSDGLNHLDNLKGTFAKLSELHCDKLHVDP
+ENFRLLGNVLVRVLACNFGPEFTPQVQAAFQKVVAGVANALAHKYH
+>HBB_TRIIN 
+VHLTPEEKALVIGLWAKVNVKEYGGEALGRLLVVYPWTQRFFEHFGDLSS
+ASAIMNNPKVKAHGEKVFTSFGDGLKHLEDLKGAFAELSELHCDKLHVDP
+ENFRLLGNVLVCVLARHFGKEFSPEAQAAYQKVVAGVANALAHKYH
+>HBB_COLLI 
+VHWSAEEKQLITSIWGKVNVADCGAEALARLLIVYPWTQRFFSSFGNLSS
+ATAISGNPNVKAHGKKVLTSFGDAVKNLDNIKGTFAQLSELHCDKLHVDP
+ENFRLLGDILVIILAAHFGKDFTPECQAAWQKLVRVVAHALARKYH
+>HBB_LARRI 
+VHWSAEEKQLITGLWGKVNVADCGAEALARLLIVYPWTQRFFASFGNLSS
+PTAINGNPMVRAHGKKVLTSFGEAVKNLDNIKNTFAQLSELHCDKLHVDP
+ENFRLLGDILIIVLAAHFAKDFTPDSQAAWQKLVRVVAHALARKYH
+>HBB1_VAREX 
+VHWTAEEKQLICSLWGKIDVGLIGGETLAGLLVIYPWTQRQFSHFGNLSS
+PTAIAGNPRVKAHGKKVLTSFGDAIKNLDNIKDTFAKLSELHCDKLHVDP
+TNFKLLGNVLVIVLADHHGKEFTPAHHAAYQKLVNVVSHSLARRYH
+>HBB2_XENTR 
+VHWTAEEKATIASVWGKVDIEQDGHDALSRLLVVYPWTQRYFSSFGNLSN
+VSAVSGNVKVKAHGNKVLSAVGSAIQHLDDVKSHLKGLSKSHAEDLHVDP
+ENFKRLADVLVIVLAAKLGSAFTPQVQAVWEKLNATLVAALSHGYF
+>HBBL_RANCA 
+VHWTAEEKAVINSVWQKVDVEQDGHEALTRLFIVYPWTQRYFSTFGDLSS
+PAAIAGNPKVHAHGKKILGAIDNAIHNLDDVKGTLHDLSEEHANELHVDP
+ENFRRLGEVLIVVLGAKLGKAFSPQVQHVWEKFIAVLVDALSHSYH
+>HBB2_TRICR 
+VHLTAEDRKEIAAILGKVNVDSLGGQCLARLIVVNPWSRRYFHDFGDLSS
+CDAICRNPKVLAHGAKVMRSIVEATKHLDNLREYYADLSVTHSLKFYVDP
+ENFKLFSGIVIVCLALTLQTDFSCHKQLAFEKLMKGVSHALGHGY
b
diff -r 000000000000 -r a6098dd0cb46 test-data/jackhmmer.domtblout
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/jackhmmer.domtblout Sat Jun 25 15:07:32 2016 -0400
[
b'@@ -0,0 +1,103 @@\n+#                                                                            --- full sequence --- -------------- this domain -------------   hmm coord   ali coord   env coord\n+# target name        accession   tlen query name           accession   qlen   E-value  score  bias   #  of  c-Evalue  i-Evalue  score  bias  from    to  from    to  from    to  acc description of target\n+#------------------- ---------- ----- -------------------- ---------- ----- --------- ------ ----- --- --- --------- --------- ------ ----- ----- ----- ----- ----- ----- ----- ---- ---------------------\n+HBB_MANSP            -            146 sp|P02185|MYG_PHYCD  -            142   7.7e-69  221.6   0.1   1   1   8.6e-69   8.6e-69  221.5   0.1     1   142     6   145     6   145 0.99 -\n+HBB_URSMA            -            146 sp|P02185|MYG_PHYCD  -            142   4.1e-68  219.3   0.2   1   1   4.5e-68   4.5e-68  219.1   0.2     1   142     6   145     6   145 0.99 -\n+HBB_RABIT            -            146 sp|P02185|MYG_PHYCD  -            142   5.6e-67  215.6   0.5   1   1   6.3e-67   6.3e-67  215.4   0.5     1   142     6   145     6   145 0.99 -\n+HBB_CALAR            -            146 sp|P02185|MYG_PHYCD  -            142   1.5e-66  214.2   0.1   1   1   1.7e-66   1.7e-66  214.0   0.1     1   142     6   145     6   145 0.99 -\n+HBB_TACAC            -            146 sp|P02185|MYG_PHYCD  -            142     5e-66  212.5   0.3   1   1   5.6e-66   5.6e-66  212.4   0.3     2   142     7   145     6   145 0.99 -\n+HBB_COLLI            -            146 sp|P02185|MYG_PHYCD  -            142   5.2e-66  212.5   0.0   1   1   5.7e-66   5.7e-66  212.3   0.0     1   142     6   145     6   145 0.99 -\n+HBE_PONPY            -            146 sp|P02185|MYG_PHYCD  -            142   6.6e-66  212.1   0.2   1   1   7.4e-66   7.4e-66  212.0   0.2     1   142     6   145     6   145 0.99 -\n+HBB_SUNMU            -            146 sp|P02185|MYG_PHYCD  -            142   7.2e-66  212.0   0.1   1   1     8e-66     8e-66  211.9   0.1     1   142     6   145     6   145 0.99 -\n+HBB_ORNAN            -            146 sp|P02185|MYG_PHYCD  -            142     1e-65  211.5   0.0   1   1   1.2e-65   1.2e-65  211.3   0.0     2   142     7   145     6   145 0.99 -\n+HBB_SPETO            -            146 sp|P02185|MYG_PHYCD  -            142   1.5e-65  211.0   0.4   1   1   1.7e-65   1.7e-65  210.8   0.4     2   142     7   145     6   145 0.99 -\n+HBB_EQUHE            -            146 sp|P02185|MYG_PHYCD  -            142   1.6e-65  210.9   0.2   1   1   1.8e-65   1.8e-65  210.7   0.2     1   142     6   145     6   145 0.99 -\n+HBB_SPECI            -            146 sp|P02185|MYG_PHYCD  -            142   2.3e-65  210.4   0.9   1   1   2.5e-65   2.5e-65  210.2   0.9     2   142     7   145     6   145 0.99 -\n+HBB_LARRI            -            146 sp|P02185|MYG_PHYCD  -            142     3e-65  210.0   0.0   1   1   3.4e-65   3.4e-65  209.8   0.0     1   142     6   145     6   145 0.99 -\n+HBB_TRIIN            -            146 sp|P02185|MYG_PHYCD  -            142     8e-65  208.6   0.1   1   1   8.9e-65   8.9e-65  208.5   0.1     1   142     6   145     6   145 0.99 -\n+HBB_TUPGL            -            146 sp|P02185|MYG_PHYCD  -            142   1.2e-62  201.6   0.0   1   1   1.3e-62   1.3e-62  201.5   0.0     1   142     6   145     6   145 0.99 -\n+HBA_MESAU            -            141 sp|P02185|MYG_PHYCD  -            142   1.5e-61  198.0   0.6   1   1   1.7e-61   1.7e-61  197.8   0.6     2   142     6   140     5   140 0.99 -\n+HBB1_VAREX           -            146 sp|P02185|MYG_PHYCD  -            142     3e-61  197.0   0.1   1   1   3.4e-61   3.4e-61  196.9   0.1     1   142     6   145     6   145 0.99 -\n+HBA_MACFA            -            141 sp|P02185|MYG_PHYCD  -            142     6e-61  196.1   1.1   1   1   6.6e-61   6.6e-61  195.9   1.1     2   142     6   140     5   140 0.99 -\n+HBA_MACSI            -            141 sp|P02185|MYG_PHYCD  -            142   9.7e-'..b'24|HBB_GORGO  -            143     1e-59  191.9   0.1   1   1   1.1e-59   1.1e-59  191.8   0.1     1   143     2   140     2   140 0.98 -\n+HBA_PROLO            -            141 sp|P02024|HBB_GORGO  -            143   1.4e-59  191.5   0.0   1   1   1.5e-59   1.5e-59  191.4   0.0     1   143     2   140     2   140 0.99 -\n+HBA_ANSSE            -            141 sp|P02024|HBB_GORGO  -            143   1.6e-59  191.3   0.4   1   1   1.8e-59   1.8e-59  191.1   0.4     1   143     2   140     2   140 0.99 -\n+HBA_PAGLA            -            141 sp|P02024|HBB_GORGO  -            143   1.7e-59  191.2   0.5   1   1   1.9e-59   1.9e-59  191.1   0.5     1   143     2   140     2   140 0.99 -\n+HBA_TRIOC            -            141 sp|P02024|HBB_GORGO  -            143   1.1e-58  188.6   0.5   1   1   1.2e-58   1.2e-58  188.4   0.5     1   143     2   140     2   140 0.99 -\n+HBAD_CHLME           -            141 sp|P02024|HBB_GORGO  -            143   2.9e-58  187.2   0.6   1   1   3.2e-58   3.2e-58  187.1   0.6     1   143     2   140     2   140 0.98 -\n+HBAZ_HORSE           -            141 sp|P02024|HBB_GORGO  -            143   3.4e-58  187.0   0.1   1   1   3.8e-58   3.8e-58  186.9   0.1     1   143     2   140     2   140 0.98 -\n+HBA_COLLI            -            141 sp|P02024|HBB_GORGO  -            143   6.7e-58  186.1   0.2   1   1   7.4e-58   7.4e-58  185.9   0.2     1   143     2   140     2   140 0.98 -\n+HBAD_PASMO           -            141 sp|P02024|HBB_GORGO  -            143   8.9e-58  185.7   0.1   1   1   9.9e-58   9.9e-58  185.5   0.1     1   143     2   140     2   140 0.98 -\n+MYG_LYCPI            -            153 sp|P02024|HBB_GORGO  -            143   1.1e-56  182.1   1.9   1   1   1.3e-56   1.3e-56  181.9   1.9     1   143     2   146     2   146 0.97 -\n+MYG_SAISC            -            153 sp|P02024|HBB_GORGO  -            143   1.1e-56  182.1   1.1   1   1   1.3e-56   1.3e-56  181.9   1.1     1   143     2   146     2   146 0.98 -\n+MYG_ESCGI            -            153 sp|P02024|HBB_GORGO  -            143   2.5e-56  181.0   1.7   1   1   2.8e-56   2.8e-56  180.8   1.7     1   143     2   146     2   146 0.97 -\n+MYG_PROGU            -            153 sp|P02024|HBB_GORGO  -            143   3.2e-56  180.6   0.2   1   1   3.6e-56   3.6e-56  180.4   0.2     1   143     2   146     2   146 0.97 -\n+MYG_HORSE            -            153 sp|P02024|HBB_GORGO  -            143   9.5e-56  179.1   1.0   1   1   1.1e-55   1.1e-55  178.9   1.0     1   143     2   146     2   146 0.97 -\n+MYG_MOUSE            -            153 sp|P02024|HBB_GORGO  -            143   1.8e-55  178.2   0.3   1   1     2e-55     2e-55  178.0   0.3     1   143     2   146     2   146 0.97 -\n+HBA4_SALIR           -            142 sp|P02024|HBB_GORGO  -            143   3.4e-55  177.3   0.1   1   1   3.8e-55   3.8e-55  177.1   0.1     1   143     2   141     2   141 0.98 -\n+HBB2_TRICR           -            145 sp|P02024|HBB_GORGO  -            143   1.8e-53  171.7   0.0   1   1     2e-53     2e-53  171.6   0.0     1   143     3   145     3   145 0.99 -\n+MYG_MUSAN            -            148 sp|P02024|HBB_GORGO  -            143     1e-44  143.3   0.3   1   1   1.1e-44   1.1e-44  143.2   0.3     5   143     2   141     1   141 0.96 -\n+#\n+# Program:         jackhmmer\n+# Version:         3.1b2 (February 2015)\n+# Pipeline mode:   SEARCH\n+# Query file:      /tmp/tmphb1nFG/files/000/dataset_1.dat\n+# Target file:     /tmp/tmphb1nFG/files/000/dataset_2.dat\n+# Option settings: jackhmmer -N 5 --tblout /tmp/tmphb1nFG/files/000/dataset_4.dat --domtblout /tmp/tmphb1nFG/files/000/dataset_5.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --fast --hand --symfrac 0.5 --wpb --EmL 200 --EmN 200 --EvL 200 --EvN 200 --EfL 100 --EfN 200 --Eft 0.04 --seed 4 --cpu 1 /tmp/tmphb1nFG/files/000/dataset_1.dat /tmp/tmphb1nFG/files/000/dataset_2.dat \n+# Current dir:     /tmp/tmphb1nFG/job_working_directory/000/3\n+# Date:            Sat Jun 25 19:33:04 2016\n+# [ok]\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/jackhmmer.out
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/jackhmmer.out Sat Jun 25 15:07:32 2016 -0400
[
b'@@ -0,0 +1,3225 @@\n+# jackhmmer :: iteratively search a protein sequence against a protein database\n+# HMMER 3.1b1 (May 2013); http://hmmer.org/\n+# Copyright (C) 2013 Howard Hughes Medical Institute.\n+# Freely distributed under the GNU General Public License (GPLv3).\n+# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -\n+# query sequence file:             /tmp/tmpwsYozTfiles/000/dataset_31.dat\n+# target sequence database:        /tmp/tmpwsYozTfiles/000/dataset_32.dat\n+# per-seq hits tabular output:     /tmp/tmpwsYozTfiles/000/dataset_34.dat\n+# per-dom hits tabular output:     /tmp/tmpwsYozTfiles/000/dataset_35.dat\n+# max ASCII text line length:      unlimited\n+# Vit filter P threshold:       <= 0.001\n+# Fwd filter P threshold:       <= 1e-05\n+# model architecture construction: fast/heuristic\n+# random number seed set to:       4\n+# number of worker threads:        2\n+# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -\n+\n+Query:       sp|P02185|MYG_PHYCD  [L=154]\n+Description: Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+\n+Scores for complete sequences (score includes all domains):\n+   --- full sequence ---   --- best 1 domain ---    -#dom-\n+    E-value  score  bias    E-value  score  bias    exp  N  Sequence   Description\n+    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------\n++   3.7e-96  310.8   5.1    4.1e-96  310.7   5.1    1.0  1  MYG_ESCGI   \n++   1.2e-91  296.2   4.6    1.4e-91  296.0   4.6    1.0  1  MYG_HORSE   \n++     1e-86  280.2   3.1    1.1e-86  280.0   3.1    1.0  1  MYG_PROGU   \n++   8.4e-86  277.2   4.7    9.3e-86  277.1   4.7    1.0  1  MYG_SAISC   \n++   1.4e-84  273.3   4.0    1.5e-84  273.1   4.0    1.0  1  MYG_LYCPI   \n++   7.4e-84  270.9   1.8    8.1e-84  270.8   1.8    1.0  1  MYG_MOUSE   \n++   2.3e-34  110.3   0.0    2.6e-34  110.2   0.0    1.0  1  MYG_MUSAN   \n++   6.6e-17   53.7   0.0    7.5e-17   53.5   0.0    1.0  1  HBAZ_HORSE  \n++   2.4e-14   45.4   0.0    2.8e-14   45.2   0.0    1.0  1  HBB_COLLI   \n++   1.3e-13   43.0   0.0    1.5e-13   42.7   0.0    1.0  1  HBB_LARRI   \n++   1.9e-12   39.2   0.1    2.3e-12   38.9   0.1    1.1  1  HBB2_XENTR  \n++   3.1e-12   38.5   0.1    3.3e-12   38.5   0.1    1.0  1  HBB_ORNAN   \n++   6.5e-12   37.5   0.3    6.9e-12   37.4   0.3    1.0  1  HBB_TRIIN   \n++   8.4e-12   37.1   0.1    9.5e-12   36.9   0.1    1.0  1  HBE_PONPY   \n++   1.1e-11   36.8   0.1    1.3e-11   36.6   0.1    1.0  1  HBB1_VAREX  \n++   2.2e-11   35.8   0.5    2.4e-11   35.6   0.5    1.0  1  HBB_SPECI   \n++   8.4e-11   33.9   0.2    8.9e-11   33.8   0.2    1.0  1  HBB_SPETO   \n++   1.1e-10   33.4   0.2    1.2e-10   33.3   0.2    1.0  1  HBB_TACAC   \n++   1.3e-10   33.3   0.0    1.4e-10   33.1   0.0    1.0  1  HBAD_PASMO  \n++   1.4e-10   33.1   0.1    1.5e-10   33.1   0.1    1.0  1  HBB_SUNMU   \n++   2.8e-10   32.2   0.1      3e-10   32.1   0.1    1.1  1  HBA_ERIEU   \n++     6e-10   31.1   0.6    6.7e-10   31.0   0.6    1.1  1  HBA2_BOSMU  \n++   6.1e-10   31.1   0.1    6.9e-10   30.9   0.1    1.1  1  HBAD_CHLME  \n++   6.6e-10   31.0   0.1      7e-10   30.9   0.1    1.0  1  HBB_URSMA   \n++   7.7e-10   30.7   0.2    9.5e-10   30.5   0.2    1.1  1  HBBL_RANCA  \n++   8.5e-10   30.6   0.2      9e-10   30.5   0.2    1.0  1  HBB_EQUHE   \n++   2.2e-09   29.3   0.2    2.4e-09   29.1   0.2    1.1  1  HBA_AILME   \n++   3.1e-09   28.8   0.0    3.3e-09   28.7   0.0    1.0  1  HBB_TUPGL   \n++   4.6e-09   28.2   0.1    5.4e-09   28.0   0.1    1.0  1  HBA4_SALIR  \n++   4.8e-09   28.2   0.2    5.4e-09   28.0   0.2    1.1  1  HBA2_GALCR  \n++   7.5e-09   27.6   0.4    8.2e-09   27.4   0.4    1.1  1  HBA_MESAU   \n++   9.2e-09   27.3   0.1    1.1e-08   27.1   0.1    1.0  1  HBB_MANSP   \n++   1.1e-08   27.0   0.3    1.2e-08   26.9   0.3    1.1  1  HBA_PONPY   \n++   1.1e-08   27.0   0.2    1.3e-08   26.8   0.2    1.1  1  HBA_PAGLA   \n++   1.2e-08   26.9   0.2    1.3e-08   26.7   0.2    1.1  1  HBA_ANSSE   \n++   2.5e-08   25.8   0.3    2.7e-08  '..b' ++de+G++aL+r+lvvyP+tk yF+++++++      gsa vk+hg +++++++++v ++ddl g l+kLselHatkl+vdp+nfk+l++ l+vv+aa fp+eftpe++ ++dk+l+++a ala+kY\n+              HBA4_SALIR   2 LSAKDKANVKAIWGKIlpKSDEIGEQALSRMLVVYPQTKAYFSHWASVA-----PGSAPVKKHGITIMNQIDDCVGHMDDLFGFLTKLSELHATKLRVDPTNFKILAHNLIVVIAAYFPAEFTPEIHLSVDKFLQQLALALAEKY 141\n+                             699*************999**************************7765.....9*****************************************************************************************9 PP\n+\n+>> HBB2_TRICR  \n+   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc\n+ ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----\n+   1 !  171.6   0.0     2e-53     2e-53       1     143 []       3     145 .]       3     145 .] 0.99\n+\n+  Alignments for each domain:\n+  == domain 1  score: 171.6 bits;  conditional E-value: 2e-53\n+                             xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF\n+  sp|P02024|HBB_GORGO-i1   1 lsaeekalvkavwgkveadevGaeaLerllvvyPetkryFdkFkdlssedavkgsakvkahgkkvltalgeavkklddlkgalakLselHatklkvdpenfkllsevlvvvLaakfpkeftpevqaaldkllaavanalaakY 143\n+                             l+ae++++++a++gkv++d++G+++L+rl+vv P+++ryF++F+dlss+da+++++kv ahg+kv++++ ea k+ld+l++ +a+Ls +H+ k+ vdpenfkl+s +++v+La +++++f+++ q a++kl+++v++al++ Y\n+              HBB2_TRICR   3 LTAEDRKEIAAILGKVNVDSLGGQCLARLIVVNPWSRRYFHDFGDLSSCDAICRNPKVLAHGAKVMRSIVEATKHLDNLREYYADLSVTHSLKFYVDPENFKLFSGIVIVCLALTLQTDFSCHKQLAFEKLMKGVSHALGHGY 145\n+                             79*******************************************************************************************************************************************99 PP\n+\n+>> MYG_MUSAN  \n+   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc\n+ ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----\n+   1 !  143.2   0.3   1.1e-44   1.1e-44       5     143 .]       2     141 ..       1     141 [. 0.96\n+\n+  Alignments for each domain:\n+  == domain 1  score: 143.2 bits;  conditional E-value: 1.1e-44\n+                             xxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF\n+  sp|P02024|HBB_GORGO-i1   5 ekalvkavwgkvead..evGaeaLerllvvyPetkryFdkFkdlssedavkgsakvkahgkkvltalgeavkklddlkgalakLselHatklkvdpenfkllsevlvvvLaakfpkeftpevqaaldkllaavanalaakY 143\n+                             ++++v++vw+ ve+d  ++G+++L rl+++yPe++++F+kFk++s   ++k++a++ka++++vl+alg++vkk++++++ +++L+++H+t++k++p++f+ ++++ v vL++++p+e++++vqaa++ +++ + +++ ++Y\n+               MYG_MUSAN   2 DWEKVNSVWSAVESDltAIGQNILLRLFEQYPESQNHFPKFKNKS-LGELKDTADIKAQADTVLSALGNIVKKKGSHSQPVKALAATHITTHKIPPHYFTKITTIAVDVLSEMYPSEMNAQVQAAFSGAFKIICSDIEKEY 141\n+                             7899********9886689**********************9998.667*************************************************************************************9999888 PP\n+\n+\n+\n+Internal pipeline statistics summary:\n+-------------------------------------\n+Query model(s):                              1  (143 nodes)\n+Target sequences:                           45  (6519 residues searched)\n+Passed MSV filter:                        45  (1); expected 0.9 (0.02)\n+Passed bias filter:                       45  (1); expected 0.9 (0.02)\n+Passed Vit filter:                        45  (1); expected 0.0 (0.001)\n+Passed Fwd filter:                        45  (1); expected 0.0 (1e-05)\n+Initial search space (Z):                 45  [actual number of targets]\n+Domain search space  (domZ):              45  [number of targets reported over threshold]\n+# CPU time: 0.34u 0.01s 00:00:00.35 Elapsed: 00:00:01.00\n+# Mc/sec: 0.93\n+\n+@@ New targets included:   0\n+@@ New alignment includes: 46 subseqs (was 46), including original query\n+@@\n+@@ CONVERGED (in 2 rounds). \n+@@\n+\n+//\n+[ok]\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/jackhmmer.tblout
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/jackhmmer.tblout Sat Jun 25 15:07:32 2016 -0400
[
b'@@ -0,0 +1,103 @@\n+#                                                               --- full sequence ---- --- best 1 domain ---- --- domain number estimation ----\n+# target name        accession  query name           accession    E-value  score  bias   E-value  score  bias   exp reg clu  ov env dom rep inc description of target\n+#------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ -----   --- --- --- --- --- --- --- --- ---------------------\n+HBB_MANSP            -          sp|P02185|MYG_PHYCD  -            7.7e-69  221.6   0.1   8.6e-69  221.5   0.1   1.0   1   0   0   1   1   1   1 -\n+HBB_URSMA            -          sp|P02185|MYG_PHYCD  -            4.1e-68  219.3   0.2   4.5e-68  219.1   0.2   1.0   1   0   0   1   1   1   1 -\n+HBB_RABIT            -          sp|P02185|MYG_PHYCD  -            5.6e-67  215.6   0.5   6.3e-67  215.4   0.5   1.0   1   0   0   1   1   1   1 -\n+HBB_CALAR            -          sp|P02185|MYG_PHYCD  -            1.5e-66  214.2   0.1   1.7e-66  214.0   0.1   1.0   1   0   0   1   1   1   1 -\n+HBB_TACAC            -          sp|P02185|MYG_PHYCD  -              5e-66  212.5   0.3   5.6e-66  212.4   0.3   1.0   1   0   0   1   1   1   1 -\n+HBB_COLLI            -          sp|P02185|MYG_PHYCD  -            5.2e-66  212.5   0.0   5.7e-66  212.3   0.0   1.0   1   0   0   1   1   1   1 -\n+HBE_PONPY            -          sp|P02185|MYG_PHYCD  -            6.6e-66  212.1   0.2   7.4e-66  212.0   0.2   1.0   1   0   0   1   1   1   1 -\n+HBB_SUNMU            -          sp|P02185|MYG_PHYCD  -            7.2e-66  212.0   0.1     8e-66  211.9   0.1   1.0   1   0   0   1   1   1   1 -\n+HBB_ORNAN            -          sp|P02185|MYG_PHYCD  -              1e-65  211.5   0.0   1.2e-65  211.3   0.0   1.0   1   0   0   1   1   1   1 -\n+HBB_SPETO            -          sp|P02185|MYG_PHYCD  -            1.5e-65  211.0   0.4   1.7e-65  210.8   0.4   1.0   1   0   0   1   1   1   1 -\n+HBB_EQUHE            -          sp|P02185|MYG_PHYCD  -            1.6e-65  210.9   0.2   1.8e-65  210.7   0.2   1.0   1   0   0   1   1   1   1 -\n+HBB_SPECI            -          sp|P02185|MYG_PHYCD  -            2.3e-65  210.4   0.9   2.5e-65  210.2   0.9   1.0   1   0   0   1   1   1   1 -\n+HBB_LARRI            -          sp|P02185|MYG_PHYCD  -              3e-65  210.0   0.0   3.4e-65  209.8   0.0   1.0   1   0   0   1   1   1   1 -\n+HBB_TRIIN            -          sp|P02185|MYG_PHYCD  -              8e-65  208.6   0.1   8.9e-65  208.5   0.1   1.0   1   0   0   1   1   1   1 -\n+HBB_TUPGL            -          sp|P02185|MYG_PHYCD  -            1.2e-62  201.6   0.0   1.3e-62  201.5   0.0   1.0   1   0   0   1   1   1   1 -\n+HBA_MESAU            -          sp|P02185|MYG_PHYCD  -            1.5e-61  198.0   0.6   1.7e-61  197.8   0.6   1.0   1   0   0   1   1   1   1 -\n+HBB1_VAREX           -          sp|P02185|MYG_PHYCD  -              3e-61  197.0   0.1   3.4e-61  196.9   0.1   1.0   1   0   0   1   1   1   1 -\n+HBA_MACFA            -          sp|P02185|MYG_PHYCD  -              6e-61  196.1   1.1   6.6e-61  195.9   1.1   1.0   1   0   0   1   1   1   1 -\n+HBA_MACSI            -          sp|P02185|MYG_PHYCD  -            9.7e-61  195.4   1.0   1.1e-60  195.2   1.0   1.0   1   0   0   1   1   1   1 -\n+HBA2_BOSMU           -          sp|P02185|MYG_PHYCD  -            3.2e-60  193.7   0.9   3.6e-60  193.6   0.9   1.0   1   0   0   1   1   1   1 -\n+HBA_PONPY            -          sp|P02185|MYG_PHYCD  -            3.2e-60  193.7   2.0   3.6e-60  193.5   2.0   1.0   1   0   0   1   1   1   1 -\n+HBA2_GALCR           -          sp|P02185|MYG_PHYCD  -            4.2e-60  193.3   1.5   4.7e-60  193.2   1.5   1.0   1   0   0   1   1   1   1 -\n+HBA_AILME            -          sp|P02185|MYG_PHYCD  -            5.7e-60  192.9   0.5   6.3e-60  192.7   0.5   1.0   1   0   0   1   1   1   1 -\n+HBA_FRAPO            -          sp|P02185|MYG_PHYCD  -            9.6e-60  192.2   0.6   1.1e-59  192.0   0.6   1.0   1 '..b'0   1   0   0   1   1   1   1 -\n+HBA2_GALCR           -          sp|P02024|HBB_GORGO  -            2.7e-60  193.8   0.5     3e-60  193.7   0.5   1.0   1   0   0   1   1   1   1 -\n+HBA_FRAPO            -          sp|P02024|HBB_GORGO  -              3e-60  193.7   0.4   3.3e-60  193.5   0.4   1.0   1   0   0   1   1   1   1 -\n+HBA_PHACO            -          sp|P02024|HBB_GORGO  -              3e-60  193.7   0.4   3.4e-60  193.5   0.4   1.0   1   0   0   1   1   1   1 -\n+HBA2_BOSMU           -          sp|P02024|HBB_GORGO  -            3.2e-60  193.6   0.3   3.5e-60  193.4   0.3   1.0   1   0   0   1   1   1   1 -\n+HBA_ERIEU            -          sp|P02024|HBB_GORGO  -              1e-59  191.9   0.1   1.1e-59  191.8   0.1   1.0   1   0   0   1   1   1   1 -\n+HBA_PROLO            -          sp|P02024|HBB_GORGO  -            1.4e-59  191.5   0.0   1.5e-59  191.4   0.0   1.0   1   0   0   1   1   1   1 -\n+HBA_ANSSE            -          sp|P02024|HBB_GORGO  -            1.6e-59  191.3   0.4   1.8e-59  191.1   0.4   1.0   1   0   0   1   1   1   1 -\n+HBA_PAGLA            -          sp|P02024|HBB_GORGO  -            1.7e-59  191.2   0.5   1.9e-59  191.1   0.5   1.0   1   0   0   1   1   1   1 -\n+HBA_TRIOC            -          sp|P02024|HBB_GORGO  -            1.1e-58  188.6   0.5   1.2e-58  188.4   0.5   1.0   1   0   0   1   1   1   1 -\n+HBAD_CHLME           -          sp|P02024|HBB_GORGO  -            2.9e-58  187.2   0.6   3.2e-58  187.1   0.6   1.0   1   0   0   1   1   1   1 -\n+HBAZ_HORSE           -          sp|P02024|HBB_GORGO  -            3.4e-58  187.0   0.1   3.8e-58  186.9   0.1   1.0   1   0   0   1   1   1   1 -\n+HBA_COLLI            -          sp|P02024|HBB_GORGO  -            6.7e-58  186.1   0.2   7.4e-58  185.9   0.2   1.0   1   0   0   1   1   1   1 -\n+HBAD_PASMO           -          sp|P02024|HBB_GORGO  -            8.9e-58  185.7   0.1   9.9e-58  185.5   0.1   1.0   1   0   0   1   1   1   1 -\n+MYG_LYCPI            -          sp|P02024|HBB_GORGO  -            1.1e-56  182.1   1.9   1.3e-56  181.9   1.9   1.0   1   0   0   1   1   1   1 -\n+MYG_SAISC            -          sp|P02024|HBB_GORGO  -            1.1e-56  182.1   1.1   1.3e-56  181.9   1.1   1.0   1   0   0   1   1   1   1 -\n+MYG_ESCGI            -          sp|P02024|HBB_GORGO  -            2.5e-56  181.0   1.7   2.8e-56  180.8   1.7   1.0   1   0   0   1   1   1   1 -\n+MYG_PROGU            -          sp|P02024|HBB_GORGO  -            3.2e-56  180.6   0.2   3.6e-56  180.4   0.2   1.0   1   0   0   1   1   1   1 -\n+MYG_HORSE            -          sp|P02024|HBB_GORGO  -            9.5e-56  179.1   1.0   1.1e-55  178.9   1.0   1.0   1   0   0   1   1   1   1 -\n+MYG_MOUSE            -          sp|P02024|HBB_GORGO  -            1.8e-55  178.2   0.3     2e-55  178.0   0.3   1.0   1   0   0   1   1   1   1 -\n+HBA4_SALIR           -          sp|P02024|HBB_GORGO  -            3.4e-55  177.3   0.1   3.8e-55  177.1   0.1   1.0   1   0   0   1   1   1   1 -\n+HBB2_TRICR           -          sp|P02024|HBB_GORGO  -            1.8e-53  171.7   0.0     2e-53  171.6   0.0   1.0   1   0   0   1   1   1   1 -\n+MYG_MUSAN            -          sp|P02024|HBB_GORGO  -              1e-44  143.3   0.3   1.1e-44  143.2   0.3   1.0   1   0   0   1   1   1   1 -\n+#\n+# Program:         jackhmmer\n+# Version:         3.1b2 (February 2015)\n+# Pipeline mode:   SEARCH\n+# Query file:      /tmp/tmphb1nFG/files/000/dataset_1.dat\n+# Target file:     /tmp/tmphb1nFG/files/000/dataset_2.dat\n+# Option settings: jackhmmer -N 5 --tblout /tmp/tmphb1nFG/files/000/dataset_4.dat --domtblout /tmp/tmphb1nFG/files/000/dataset_5.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --fast --hand --symfrac 0.5 --wpb --EmL 200 --EmN 200 --EvL 200 --EvN 200 --EfL 100 --EfN 200 --Eft 0.04 --seed 4 --cpu 1 /tmp/tmphb1nFG/files/000/dataset_1.dat /tmp/tmphb1nFG/files/000/dataset_2.dat \n+# Current dir:     /tmp/tmphb1nFG/job_working_directory/000/3\n+# Date:            Sat Jun 25 19:33:04 2016\n+# [ok]\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/nhmmer.out
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/nhmmer.out Sat Jun 25 15:07:32 2016 -0400
[
@@ -0,0 +1,113 @@
+# nhmmer :: search a DNA model or alignment against a DNA database
+# HMMER 3.1b2 (February 2015); http://hmmer.org/
+# Copyright (C) 2015 Howard Hughes Medical Institute.
+# Freely distributed under the GNU General Public License (GPLv3).
+# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
+# query file:                      /tmp/tmpprnvgs/files/000/dataset_1.dat
+# target sequence database:        /tmp/tmpprnvgs/files/000/dataset_2.dat
+# hits tabular output:             /tmp/tmpprnvgs/files/000/dataset_4.dat
+# hits output in Dfam format:      None
+# max ASCII text line length:      unlimited
+# SSV filter P threshold:       <= 0.02
+# Vit filter P threshold:       <= 0.001
+# Fwd filter P threshold:       <= 1e-05
+# input query is asserted as:      DNA
+# random number seed set to:       4
+# number of worker threads:        1
+# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
+
+Query:       MADE1  [M=80]
+Accession:   DF0000629.2
+Description: MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon
+Scores for complete hits:
+    E-value  score  bias  Sequence                       start    end  Description
+    ------- ------ -----  --------                       -----  -----  -----------
+    1.2e-10   38.6   7.4  humanchr1/239220001-239550000 302390 302466  
+    7.8e-08   29.6   8.3  humanchr1/239220001-239550000 174456 174498  
+    1.2e-07   28.9   6.0  humanchr1/239220001-239550000 302466 302390  
+    7.2e-06   23.3   7.0  humanchr1/239220001-239550000 174493 174456  
+  ------ inclusion threshold ------
+        1.4    6.3   7.0  humanchr1/239220001-239550000 304073 304104  
+
+
+Annotation for each hit  (and alignments):
+>> humanchr1/239220001-239550000  
+    score  bias    Evalue   hmmfrom    hmm to     alifrom    ali to      envfrom    env to       sq len      acc
+   ------ ----- ---------   -------   -------    --------- ---------    --------- ---------    ---------    ----
+ !   38.6   7.4   1.2e-10         4        80 .]    302390    302466 ..    302387    302466 ..    330000    0.87
+
+  Alignment:
+  score: 38.6 bits
+                                       xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
+                          MADE1      4 ggttggtgcaaaagtaattgcggtttttgccattacttttaatggc....aaaaaccgcaattacttttgcaccaacctaa 80    
+                                       ggt ggtgcaaaa  aattg ggtttttgccatt cttttaat gc    a aaa  g a  t ctttt caccaa ctaa
+  humanchr1/239220001-239550000 302390 GGTCGGTGCAAAATCAATTGTGGTTTTTGCCATTGCTTTTAATTGCttttA-AAA--GTA-ATGCTTTTACACCAATCTAA 302466
+                                       899******************************************955533.443..334.4689***********99986 PP
+
+>> humanchr1/239220001-239550000  
+    score  bias    Evalue   hmmfrom    hmm to     alifrom    ali to      envfrom    env to       sq len      acc
+   ------ ----- ---------   -------   -------    --------- ---------    --------- ---------    ---------    ----
+ !   29.6   8.3   7.8e-08         1        43 [.    174456    174498 ..    174456    174518 ..    330000    0.92
+
+  Alignment:
+  score: 29.6 bits
+                                       xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
+                          MADE1      1 ttaggttggtgcaaaagtaattgcggtttttgccattactttt 43    
+                                       ttaggtt gtgcaaaagtaattg ggtttttg cattactttt
+  humanchr1/239220001-239550000 174456 TTAGGTTAGTGCAAAAGTAATTGTGGTTTTTGTCATTACTTTT 174498
+                                       589************************************9975 PP
+
+>> humanchr1/239220001-239550000  
+    score  bias    Evalue   hmmfrom    hmm to     alifrom    ali to      envfrom    env to       sq len      acc
+   ------ ----- ---------   -------   -------    --------- ---------    --------- ---------    ---------    ----
+ !   28.9   6.0   1.2e-07         1        77 [.    302466    302390 ..    302466    302387 ..    330000    0.74
+
+  Alignment:
+  score: 28.9 bits
+                                       xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
+                          MADE1      1 ttaggttggtgcaaaagtaattgcggtttttgccattactttt................aatggcaaaaaccgcaattacttttgcaccaacc 77    
+                                       ttag ttggtg aaaag                cattactttt                aatggcaaaaacc caatt  ttttgcacc acc
+  humanchr1/239220001-239550000 302466 TTAGATTGGTGTAAAAG----------------CATTACTTTTaaaagcaattaaaagcAATGGCAAAAACCACAATTGATTTTGCACCGACC 302390
+                                       68999999999999998................5666777776222222222222222268****************************9998 PP
+
+>> humanchr1/239220001-239550000  
+    score  bias    Evalue   hmmfrom    hmm to     alifrom    ali to      envfrom    env to       sq len      acc
+   ------ ----- ---------   -------   -------    --------- ---------    --------- ---------    ---------    ----
+ !   23.3   7.0   7.2e-06        43        80 .]    174493    174456 ..    174513    174456 ..    330000    0.91
+
+  Alignment:
+  score: 23.3 bits
+                                       xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
+                          MADE1     43 taatggcaaaaaccgcaattacttttgcaccaacctaa 80    
+                                       taatg caaaaacc caattacttttgcac aacctaa
+  humanchr1/239220001-239550000 174493 TAATGACAAAAACCACAATTACTTTTGCACTAACCTAA 174456
+                                       689********************************985 PP
+
+>> humanchr1/239220001-239550000  
+    score  bias    Evalue   hmmfrom    hmm to     alifrom    ali to      envfrom    env to       sq len      acc
+   ------ ----- ---------   -------   -------    --------- ---------    --------- ---------    ---------    ----
+ ?    6.3   7.0       1.4        41        72 ..    304073    304104 ..    304053    304109 ..    330000    0.85
+
+  Alignment:
+  score: 6.3 bits
+                                       xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
+                          MADE1     41 tttaatggcaaaaaccgcaattacttttgcac 72    
+                                       tt a tgg aaaaa   ca tta ttttgca 
+  humanchr1/239220001-239550000 304073 TTAAGTGGGAAAAAATACACTTATTTTTGCAT 304104
+                                       455779************************86 PP
+
+
+
+Internal pipeline statistics summary:
+-------------------------------------
+Query model(s):                              1  (80 nodes)
+Target sequences:                            1  (660000 residues searched)
+Residues passing SSV filter:             61794  (0.0936); expected (0.02)
+Residues passing bias filter:            46199  (0.07); expected (0.02)
+Residues passing Vit filter:              2752  (0.00417); expected (0.001)
+Residues passing Fwd filter:              2526  (0.00383); expected (1e-05)
+Total number of hits:                        5  (0.000405)
+# CPU time: 0.03u 0.00s 00:00:00.03 Elapsed: 00:00:00.03
+# Mc/sec: 1760.00
+//
+[ok]
b
diff -r 000000000000 -r a6098dd0cb46 test-data/phmmer.domtblout
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/phmmer.domtblout Sat Jun 25 15:07:32 2016 -0400
[
b'@@ -0,0 +1,102 @@\n+#                                                                            --- full sequence --- -------------- this domain -------------   hmm coord   ali coord   env coord\n+# target name        accession   tlen query name           accession   qlen   E-value  score  bias   #  of  c-Evalue  i-Evalue  score  bias  from    to  from    to  from    to  acc description of target\n+#------------------- ---------- ----- -------------------- ---------- ----- --------- ------ ----- --- --- --------- --------- ------ ----- ----- ----- ----- ----- ----- ----- ---- ---------------------\n+sp|P02185|MYG_PHYCD  -            154 MYG_ESCGI            -            153   1.9e-97  310.4   5.6   1   1   2.1e-97   2.1e-97  310.3   5.6     1   153     2   154     2   154 1.00 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -            147 MYG_ESCGI            -            153   3.2e-11   30.7   0.1   1   1   3.5e-11   3.5e-11   30.6   0.1     6   146     8   146     3   147 0.91 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -            154 MYG_HORSE            -            153   7.1e-93  295.7   5.0   1   1   7.9e-93   7.9e-93  295.6   5.0     2   153     3   154     2   154 0.99 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -            147 MYG_HORSE            -            153   7.5e-12   32.7   0.1   1   1     9e-12     9e-12   32.5   0.1     7   146     9   146     4   147 0.92 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -            154 MYG_PROGU            -            153   7.4e-88  279.4   3.7   1   1   8.3e-88   8.3e-88  279.2   3.7     2   153     3   154     2   154 0.99 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -            147 MYG_PROGU            -            153   1.5e-12   35.0   0.1   1   1   1.6e-12   1.6e-12   34.9   0.1     6   146     8   146     3   147 0.92 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -            154 MYG_SAISC            -            153     5e-87  276.6   4.6   1   1   5.5e-87   5.5e-87  276.5   4.6     2   153     3   154     2   154 0.99 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -            147 MYG_SAISC            -            153     1e-12   35.5   0.1   1   1   1.1e-12   1.1e-12   35.3   0.1     6   146     8   146     3   147 0.93 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -            154 MYG_LYCPI            -            153     7e-86  272.9   4.1   1   1   7.8e-86   7.8e-86  272.8   4.1     2   153     3   154     2   154 0.99 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -            147 MYG_LYCPI            -            153   5.6e-15   42.8   0.0   1   1   6.1e-15   6.1e-15   42.7   0.0     6   146     8   146     3   147 0.94 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -            154 MYG_MOUSE            -            153     6e-85  270.1   2.6   1   1   6.7e-85   6.7e-85  269.9   2.6     2   153     3   154     2   154 0.99 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -            147 MYG_MOUSE            -            153   3.2e-12   34.0   0.0   1   1   3.5e-12   3.5e-12   33.9   0.0     6   146     8   146     3   147 0.93 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -            154 MYG_MUSAN            -            148     1e-35  110.0   0.1   1   1   1.1e-35   1.1e-35  109.9   0.1     2   148     7   154     6   154 0.98 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -            147 MYG_MUSAN            -            148   8.3e-09   22.9   0.0   1   1   9.1e-09   9.1e-09   22.7   0.0     6   131    12   136     7   147 0.87 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -            147 HBA_AILME  '..b'  30.0   0.1   1   1   4.5e-11   4.5e-11   29.7   0.1     7   145     7   147     2   148 0.89 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -            147 HBB_TRIIN            -            146   8.2e-84  265.9   0.4   1   1   9.1e-84   9.1e-84  265.8   0.4     1   146     2   147     2   147 1.00 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -            154 HBB_TRIIN            -            146   1.2e-13   38.3   0.6   1   1   1.3e-13   1.3e-13   38.2   0.6     6   145     6   147     1   148 0.89 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -            147 HBB_COLLI            -            146     6e-72  227.2   0.1   1   1   6.7e-72   6.7e-72  227.1   0.1     1   146     2   147     2   147 0.99 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -            154 HBB_COLLI            -            146   2.2e-16   47.0   0.1   1   1   2.5e-16   2.5e-16   46.8   0.1     6   145     6   147     2   148 0.94 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -            147 HBB_LARRI            -            146     6e-70  220.8   0.1   1   1   6.7e-70   6.7e-70  220.6   0.1     1   146     2   147     2   147 0.99 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -            154 HBB_LARRI            -            146   1.3e-15   44.6   0.1   1   1   1.5e-15   1.5e-15   44.3   0.1     6   145     6   147     2   148 0.94 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -            147 HBB1_VAREX           -            146   4.4e-67  211.9   0.3   1   1     5e-67     5e-67  211.8   0.3     1   146     2   147     2   147 1.00 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -            154 HBB1_VAREX           -            146     2e-13   37.8   0.4   1   1   2.4e-13   2.4e-13   37.6   0.4     7   145     7   147     3   148 0.90 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -            147 HBB2_XENTR           -            146   9.7e-53  165.2   0.1   1   1   1.1e-52   1.1e-52  165.0   0.1     1   145     2   146     2   147 0.99 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -            154 HBB2_XENTR           -            146   8.5e-14   39.0   0.2   1   1   1.1e-13   1.1e-13   38.7   0.2    10   130    10   132     4   142 0.86 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -            147 HBBL_RANCA           -            146   6.8e-57  178.6   0.1   1   1   7.5e-57   7.5e-57  178.4   0.1     1   146     2   147     2   147 0.99 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -            154 HBBL_RANCA           -            146   2.1e-11   31.0   0.4   1   1   2.5e-11   2.5e-11   30.8   0.4    10   134    10   136     3   147 0.87 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -            147 HBB2_TRICR           -            145   2.7e-46  144.3   0.0   1   1   1.5e-46     3e-46  144.1   0.0     1   145     2   146     2   146 0.98 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+#\n+# Program:         phmmer\n+# Version:         3.1b2 (February 2015)\n+# Pipeline mode:   SEARCH\n+# Query file:      /tmp/tmpqKBUss/files/000/dataset_1.dat\n+# Target file:     /tmp/tmpqKBUss/files/000/dataset_2.dat\n+# Option settings: phmmer --tblout /tmp/tmpqKBUss/files/000/dataset_4.dat --domtblout /tmp/tmpqKBUss/files/000/dataset_5.dat --pfamtblout /tmp/tmpqKBUss/files/000/dataset_6.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --EmL 200 --EmN 200 --EvL 200 --EvN 200 --EfL 100 --EfN 200 --Eft 0.04 --seed 4 --cpu 1 /tmp/tmpqKBUss/files/000/dataset_1.dat /tmp/tmpqKBUss/files/000/dataset_2.dat \n+# Current dir:     /tmp/tmpqKBUss/job_working_directory/000/3\n+# Date:            Sat Jun 25 19:48:26 2016\n+# [ok]\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/phmmer.out
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/phmmer.out Sat Jun 25 15:07:32 2016 -0400
[
b'@@ -0,0 +1,2210 @@\n+# phmmer :: search a protein sequence against a protein database\n+# HMMER 3.1b1 (May 2013); http://hmmer.org/\n+# Copyright (C) 2013 Howard Hughes Medical Institute.\n+# Freely distributed under the GNU General Public License (GPLv3).\n+# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -\n+# query sequence file:             test-data/globins45.fa\n+# target sequence database:        test-data/uniprot_matches.fasta\n+# per-seq hits tabular output:     test-data/phmmer.tblout\n+# per-dom hits tabular output:     test-data/phmmer.domtblout\n+# pfam-style tabular hit output:   test-data/phmmer.pfamtblout\n+# max ASCII text line length:      unlimited\n+# Vit filter P threshold:       <= 0.001\n+# Fwd filter P threshold:       <= 1e-05\n+# random number seed set to:       4\n+# number of worker threads:        2\n+# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -\n+\n+Query:       MYG_ESCGI  [L=153]\n+Scores for complete sequences (score includes all domains):\n+   --- full sequence ---   --- best 1 domain ---    -#dom-\n+    E-value  score  bias    E-value  score  bias    exp  N  Sequence            Description\n+    ------- ------ -----    ------- ------ -----   ---- --  --------            -----------\n+    1.9e-97  310.4   5.6    2.1e-97  310.3   5.6    1.0  1  sp|P02185|MYG_PHYCD  Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+    3.2e-11   30.7   0.1    3.5e-11   30.6   0.1    1.0  1  sp|P02024|HBB_GORGO  Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+\n+\n+Domain annotation for each sequence (and alignments):\n+>> sp|P02185|MYG_PHYCD  Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc\n+ ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----\n+   1 !  310.3   5.6   2.1e-97   2.1e-97       1     153 []       2     154 .]       2     154 .] 1.00\n+\n+  Alignments for each domain:\n+  == domain 1  score: 310.3 bits;  conditional E-value: 2.1e-97\n+            MYG_ESCGI   1 vlsdaewqlvlniwakveadvaghgqdilirlfkghpetlekfdkfkhlkteaemkasedlkkhgntvltalggilkkkghheaelkplaqshatkhkipikylefisdaiihvlhsrhpgdfgadaqaamnkalelfrkdiaakykelgfqg 153\n+                          vls+ ewqlvl++wakveadvaghgqdilirlfk+hpetlekfd+fkhlkteaemkasedlkkhg tvltalg+ilkkkghheaelkplaqshatkhkipikylefis+aiihvlhsrhpgdfgadaq amnkalelfrkdiaakykelg+qg\n+  sp|P02185|MYG_PHYCD   2 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGYQG 154\n+                          79******************************************************************************************************************************************************8 PP\n+\n+>> sp|P02024|HBB_GORGO  Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc\n+ ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----\n+   1 !   30.6   0.1   3.5e-11   3.5e-11       6     146 ..       8     146 ..       3     147 .] 0.91\n+\n+  Alignments for each domain:\n+  == domain 1  score: 30.6 bits;  conditional E-value: 3.5e-11\n+            MYG_ESCGI   6 ewqlvlniwakveadvaghgqdilirlfkghpetlekfdkfkhlkteaemkasedlkkhgntvltalggilkkkghheaelkplaqshatkhkipikylefisdaiihvlhsrhpgdfgadaqaamnkalelfrkdiaaky 146\n+                          e   v  +w kv  d  g   + l rl+  +p t   f+ f  l t   +  +  +k hg  vl a++  l    + +  +  l++ h  k  +  + ++++ + ++ vl  +   +f    qaa  k +      +a ky\n+  sp|P02024|HBB_GORGO   8 EKSAVTALWGKVNVDEVG--GEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKY 146\n+                          6677889******99876..57899**********************9999*****************9999999****************99999999***********8888889**********99887777777776'..b'.. 0.87\n+\n+  Alignments for each domain:\n+  == domain 1  score: 30.8 bits;  conditional E-value: 2.5e-11\n+           HBBL_RANCA  10 vinsvwqkvdveqdgh..ealtrlfivypwtqryfstfgdlsspaaiagnpkvhahgkkilgaidnaihnlddvkgtlhdlseehanelhvdpenfrrlgevlivvlgaklgkafspqvqhvwekfi 134\n+                          ++  vw kv+ +  gh  + l rlf  +p t + f  f  l + a + ++  +  hg  +l a+   +      ++ l  l++ ha +  +  + ++ ++e +i vl ++    f    q    k +\n+  sp|P02185|MYG_PHYCD  10 LVLHVWAKVEADVAGHgqDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKAL 136\n+                          56679***977766653389*********************************************999*******************988887888899*******999988888888887776665 PP\n+\n+\n+\n+Internal pipeline statistics summary:\n+-------------------------------------\n+Query model(s):                              1  (146 nodes)\n+Target sequences:                            2  (301 residues searched)\n+Passed MSV filter:                         2  (1); expected 0.0 (0.02)\n+Passed bias filter:                        2  (1); expected 0.0 (0.02)\n+Passed Vit filter:                         2  (1); expected 0.0 (0.001)\n+Passed Fwd filter:                         2  (1); expected 0.0 (1e-05)\n+Initial search space (Z):                  2  [actual number of targets]\n+Domain search space  (domZ):               2  [number of targets reported over threshold]\n+# CPU time: 0.03u 0.00s 00:00:00.03 Elapsed: 00:00:00.03\n+# Mc/sec: 1.46\n+//\n+Query:       HBB2_TRICR  [L=145]\n+Scores for complete sequences (score includes all domains):\n+   --- full sequence ---   --- best 1 domain ---    -#dom-\n+    E-value  score  bias    E-value  score  bias    exp  N  Sequence            Description\n+    ------- ------ -----    ------- ------ -----   ---- --  --------            -----------\n+    2.7e-46  144.3   0.0      3e-46  144.1   0.0    1.0  1  sp|P02024|HBB_GORGO  Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+\n+\n+Domain annotation for each sequence (and alignments):\n+>> sp|P02024|HBB_GORGO  Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc\n+ ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----\n+   1 !  144.1   0.0   1.5e-46     3e-46       1     145 []       2     146 ..       2     146 .. 0.98\n+\n+  Alignments for each domain:\n+  == domain 1  score: 144.1 bits;  conditional E-value: 1.5e-46\n+           HBB2_TRICR   1 vhltaedrkeiaailgkvnvdslggqclarlivvnpwsrryfhdfgdlsscdaicrnpkvlahgakvmrsiveatkhldnlreyyadlsvthslkfyvdpenfklfsgivivclaltlqtdfschkqlafeklmkgvshalghgy 145\n+                          vhlt e++  + a+ gkvnvd +gg++l rl+vv pw++r+f+ fgdls+ da+  npkv ahg kv+ ++ +   hldnl+  +a ls  h  k++vdpenfkl+ ++++  la  +  +f+   q a++k++ gv++al+h y\n+  sp|P02024|HBB_GORGO   2 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKY 146\n+                          8*********************************************************************************************************9998888999***************************87 PP\n+\n+\n+\n+Internal pipeline statistics summary:\n+-------------------------------------\n+Query model(s):                              1  (145 nodes)\n+Target sequences:                            2  (301 residues searched)\n+Passed MSV filter:                         2  (1); expected 0.0 (0.02)\n+Passed bias filter:                        2  (1); expected 0.0 (0.02)\n+Passed Vit filter:                         2  (1); expected 0.0 (0.001)\n+Passed Fwd filter:                         1  (0.5); expected 0.0 (1e-05)\n+Initial search space (Z):                  2  [actual number of targets]\n+Domain search space  (domZ):               1  [number of targets reported over threshold]\n+# CPU time: 0.03u 0.00s 00:00:00.03 Elapsed: 00:00:00.04\n+# Mc/sec: 1.09\n+//\n+[ok]\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/phmmer.pfamtblout
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/phmmer.pfamtblout Sat Jun 25 15:07:32 2016 -0400
[
b'@@ -0,0 +1,683 @@\n+# Sequence scores\n+# ---------------\n+#\n+# name                  bits   E-value   n   exp  bias    description\n+# ------------------- ------ --------- --- ----- -----    ---------------------\n+sp|P02185|MYG_PHYCD    310.4   1.9e-97   1   1.0   5.6    Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO     30.7   3.2e-11   1   1.0   0.1    Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+\n+# Domain scores\n+# -------------\n+#\n+#  name                 bits   E-value   hit  bias env-st env-en ali-st ali-en hmm-st hmm-en     description\n+# ------------------- ------ --------- ----- ----- ------ ------ ------ ------ ------ ------      ---------------------\n+sp|P02185|MYG_PHYCD    310.3   2.1e-97     1   5.6      2    154      2    154      1    153     Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO     30.6   3.5e-11     1   0.1      3    147      8    146      6    146     Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+# Sequence scores\n+# ---------------\n+#\n+# name                  bits   E-value   n   exp  bias    description\n+# ------------------- ------ --------- --- ----- -----    ---------------------\n+sp|P02185|MYG_PHYCD    295.7   7.1e-93   1   1.0   5.0    Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO     32.7   7.5e-12   1   1.0   0.1    Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+\n+# Domain scores\n+# -------------\n+#\n+#  name                 bits   E-value   hit  bias env-st env-en ali-st ali-en hmm-st hmm-en     description\n+# ------------------- ------ --------- ----- ----- ------ ------ ------ ------ ------ ------      ---------------------\n+sp|P02185|MYG_PHYCD    295.6   7.9e-93     1   5.0      2    154      3    154      2    153     Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO     32.5     9e-12     1   0.1      4    147      9    146      7    146     Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+# Sequence scores\n+# ---------------\n+#\n+# name                  bits   E-value   n   exp  bias    description\n+# ------------------- ------ --------- --- ----- -----    ---------------------\n+sp|P02185|MYG_PHYCD    279.4   7.4e-88   1   1.0   3.7    Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO     35.0   1.5e-12   1   1.0   0.1    Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+\n+# Domain scores\n+# -------------\n+#\n+#  name                 bits   E-value   hit  bias env-st env-en ali-st ali-en hmm-st hmm-en     description\n+# ------------------- ------ --------- ----- ----- ------ ------ ------ ------ ------ ------      ---------------------\n+sp|P02185|MYG_PHYCD    279.2   8.3e-88     1   3.7      2    154      3    154      2    153     Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO     34.9   1.6e-12     1   0.1      3    147      8    146      6    146     Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+# Sequence scores\n+# ---------------\n+#\n+# name                  bits   E-value   n   exp  bias    description\n+# ------------------- ------ --------- --- ----- -----    ---------------------\n+sp|P02185|MYG_PHYCD    276.6     5e-87   1   1.0   4.6    Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO     35.5     1e-12   1   1.0   0.1    Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+\n+# Domain scores\n+# -------------\n+#\n+#  name                 bits   E-value   hit  bias env-st env-en ali-st ali-en hmm-st hmm-en     description\n+# ------------------- ------ --------- ----- ----- ------ ------ ------ ------ ------ ------      ---------------------\n+sp|P02185|MYG_PHYCD    276.5   5.5e-87     1   4.6      2    154      3    154      2    153     Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO     35.3   1.1e-12     1   0.1      3    147      8    146      6    146     Hemoglobin subunit beta OS=Go'..b'ias env-st env-en ali-st ali-en hmm-st hmm-en     description\n+# ------------------- ------ --------- ----- ----- ------ ------ ------ ------ ------ ------      ---------------------\n+sp|P02024|HBB_GORGO    211.8     5e-67     1   0.3      2    147      2    147      1    146     Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD     37.6   2.4e-13     1   0.4      3    148      7    147      7    145     Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+# Sequence scores\n+# ---------------\n+#\n+# name                  bits   E-value   n   exp  bias    description\n+# ------------------- ------ --------- --- ----- -----    ---------------------\n+sp|P02024|HBB_GORGO    165.2   9.7e-53   1   1.0   0.1    Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD     39.0   8.5e-14   1   1.0   0.2    Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+\n+# Domain scores\n+# -------------\n+#\n+#  name                 bits   E-value   hit  bias env-st env-en ali-st ali-en hmm-st hmm-en     description\n+# ------------------- ------ --------- ----- ----- ------ ------ ------ ------ ------ ------      ---------------------\n+sp|P02024|HBB_GORGO    165.0   1.1e-52     1   0.1      2    147      2    146      1    145     Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD     38.7   1.1e-13     1   0.2      4    142     10    132     10    130     Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+# Sequence scores\n+# ---------------\n+#\n+# name                  bits   E-value   n   exp  bias    description\n+# ------------------- ------ --------- --- ----- -----    ---------------------\n+sp|P02024|HBB_GORGO    178.6   6.8e-57   1   1.0   0.1    Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD     31.0   2.1e-11   1   1.0   0.4    Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+\n+# Domain scores\n+# -------------\n+#\n+#  name                 bits   E-value   hit  bias env-st env-en ali-st ali-en hmm-st hmm-en     description\n+# ------------------- ------ --------- ----- ----- ------ ------ ------ ------ ------ ------      ---------------------\n+sp|P02024|HBB_GORGO    178.4   7.5e-57     1   0.1      2    147      2    147      1    146     Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD     30.8   2.5e-11     1   0.4      3    147     10    136     10    134     Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+# Sequence scores\n+# ---------------\n+#\n+# name                  bits   E-value   n   exp  bias    description\n+# ------------------- ------ --------- --- ----- -----    ---------------------\n+sp|P02024|HBB_GORGO    144.3   2.7e-46   1   1.0   0.0    Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+\n+# Domain scores\n+# -------------\n+#\n+#  name                 bits   E-value   hit  bias env-st env-en ali-st ali-en hmm-st hmm-en     description\n+# ------------------- ------ --------- ----- ----- ------ ------ ------ ------ ------ ------      ---------------------\n+sp|P02024|HBB_GORGO    144.1     3e-46     1   0.0      2    146      2    146      1    145     Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+#\n+# Program:         phmmer\n+# Version:         3.1b2 (February 2015)\n+# Pipeline mode:   SEARCH\n+# Query file:      /tmp/tmpqKBUss/files/000/dataset_1.dat\n+# Target file:     /tmp/tmpqKBUss/files/000/dataset_2.dat\n+# Option settings: phmmer --tblout /tmp/tmpqKBUss/files/000/dataset_4.dat --domtblout /tmp/tmpqKBUss/files/000/dataset_5.dat --pfamtblout /tmp/tmpqKBUss/files/000/dataset_6.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --EmL 200 --EmN 200 --EvL 200 --EvN 200 --EfL 100 --EfN 200 --Eft 0.04 --seed 4 --cpu 1 /tmp/tmpqKBUss/files/000/dataset_1.dat /tmp/tmpqKBUss/files/000/dataset_2.dat \n+# Current dir:     /tmp/tmpqKBUss/job_working_directory/000/3\n+# Date:            Sat Jun 25 19:48:26 2016\n+# [ok]\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/phmmer.tblout
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/phmmer.tblout Sat Jun 25 15:07:32 2016 -0400
[
b'@@ -0,0 +1,102 @@\n+#                                                               --- full sequence ---- --- best 1 domain ---- --- domain number estimation ----\n+# target name        accession  query name           accession    E-value  score  bias   E-value  score  bias   exp reg clu  ov env dom rep inc description of target\n+#------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ -----   --- --- --- --- --- --- --- --- ---------------------\n+sp|P02185|MYG_PHYCD  -          MYG_ESCGI            -            1.9e-97  310.4   5.6   2.1e-97  310.3   5.6   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          MYG_ESCGI            -            3.2e-11   30.7   0.1   3.5e-11   30.6   0.1   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          MYG_HORSE            -            7.1e-93  295.7   5.0   7.9e-93  295.6   5.0   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          MYG_HORSE            -            7.5e-12   32.7   0.1     9e-12   32.5   0.1   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          MYG_PROGU            -            7.4e-88  279.4   3.7   8.3e-88  279.2   3.7   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          MYG_PROGU            -            1.5e-12   35.0   0.1   1.6e-12   34.9   0.1   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          MYG_SAISC            -              5e-87  276.6   4.6   5.5e-87  276.5   4.6   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          MYG_SAISC            -              1e-12   35.5   0.1   1.1e-12   35.3   0.1   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          MYG_LYCPI            -              7e-86  272.9   4.1   7.8e-86  272.8   4.1   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          MYG_LYCPI            -            5.6e-15   42.8   0.0   6.1e-15   42.7   0.0   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          MYG_MOUSE            -              6e-85  270.1   2.6   6.7e-85  269.9   2.6   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          MYG_MOUSE            -            3.2e-12   34.0   0.0   3.5e-12   33.9   0.0   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          MYG_MUSAN            -              1e-35  110.0   0.1   1.1e-35  109.9   0.1   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          MYG_MUSAN            -            8.3e-09   22.9   0.0   9.1e-09   22.7   0.0   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          HBA_AILME            -            1.4e-34  106.1   0.2   1.7e-34  105.9   0.2   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          HBA_AILME            -            5.4e-11   29.8   0.5   6.4e-11   29.6   0.5   1.1   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          HBA_PROLO            -            1.9e-33  102.5   0.2   2.2e-33  102.3   0.2   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          HBA_PROLO            -  '..b'a gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          HBB_RABIT            -            5.9e-10   26.2   0.4   6.4e-10   26.1   0.4   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          HBB_TUPGL            -            8.5e-84  265.6   0.2   9.5e-84  265.4   0.2   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          HBB_TUPGL            -            3.8e-11   30.0   0.1   4.5e-11   29.7   0.1   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          HBB_TRIIN            -            8.2e-84  265.9   0.4   9.1e-84  265.8   0.4   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          HBB_TRIIN            -            1.2e-13   38.3   0.6   1.3e-13   38.2   0.6   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          HBB_COLLI            -              6e-72  227.2   0.1   6.7e-72  227.1   0.1   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          HBB_COLLI            -            2.2e-16   47.0   0.1   2.5e-16   46.8   0.1   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          HBB_LARRI            -              6e-70  220.8   0.1   6.7e-70  220.6   0.1   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          HBB_LARRI            -            1.3e-15   44.6   0.1   1.5e-15   44.3   0.1   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          HBB1_VAREX           -            4.4e-67  211.9   0.3     5e-67  211.8   0.3   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          HBB1_VAREX           -              2e-13   37.8   0.4   2.4e-13   37.6   0.4   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          HBB2_XENTR           -            9.7e-53  165.2   0.1   1.1e-52  165.0   0.1   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          HBB2_XENTR           -            8.5e-14   39.0   0.2   1.1e-13   38.7   0.2   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          HBBL_RANCA           -            6.8e-57  178.6   0.1   7.5e-57  178.4   0.1   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+sp|P02185|MYG_PHYCD  -          HBBL_RANCA           -            2.1e-11   31.0   0.4   2.5e-11   30.8   0.4   1.0   1   0   0   1   1   1   1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2\n+sp|P02024|HBB_GORGO  -          HBB2_TRICR           -            2.7e-46  144.3   0.0     3e-46  144.1   0.0   1.0   1   0   0   1   1   1   1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2\n+#\n+# Program:         phmmer\n+# Version:         3.1b2 (February 2015)\n+# Pipeline mode:   SEARCH\n+# Query file:      /tmp/tmpqKBUss/files/000/dataset_1.dat\n+# Target file:     /tmp/tmpqKBUss/files/000/dataset_2.dat\n+# Option settings: phmmer --tblout /tmp/tmpqKBUss/files/000/dataset_4.dat --domtblout /tmp/tmpqKBUss/files/000/dataset_5.dat --pfamtblout /tmp/tmpqKBUss/files/000/dataset_6.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --EmL 200 --EmN 200 --EvL 200 --EvN 200 --EfL 100 --EfN 200 --Eft 0.04 --seed 4 --cpu 1 /tmp/tmpqKBUss/files/000/dataset_1.dat /tmp/tmpqKBUss/files/000/dataset_2.dat \n+# Current dir:     /tmp/tmpqKBUss/job_working_directory/000/3\n+# Date:            Sat Jun 25 19:48:26 2016\n+# [ok]\n'
b
diff -r 000000000000 -r a6098dd0cb46 test-data/uniprot_globins_match.out
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/uniprot_globins_match.out Sat Jun 25 15:07:32 2016 -0400
[
@@ -0,0 +1,67 @@
+# hmmsearch :: search profile(s) against a sequence database
+# HMMER 3.1b2 (February 2015); http://hmmer.org/
+# Copyright (C) 2015 Howard Hughes Medical Institute.
+# Freely distributed under the GNU General Public License (GPLv3).
+# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
+# query HMM file:                  /tmp/tmpJW6ntL/files/000/dataset_1.dat
+# target sequence database:        /tmp/tmpJW6ntL/files/000/dataset_2.dat
+# per-seq hits tabular output:     /tmp/tmpJW6ntL/files/000/dataset_4.dat
+# per-dom hits tabular output:     /tmp/tmpJW6ntL/files/000/dataset_5.dat
+# pfam-style tabular hit output:   /tmp/tmpJW6ntL/files/000/dataset_6.dat
+# max ASCII text line length:      unlimited
+# Vit filter P threshold:       <= 0.001
+# Fwd filter P threshold:       <= 1e-05
+# random number seed set to:       4
+# number of worker threads:        1
+# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
+
+Query:       globins4  [M=149]
+Scores for complete sequences (score includes all domains):
+   --- full sequence ---   --- best 1 domain ---    -#dom-
+    E-value  score  bias    E-value  score  bias    exp  N  Sequence            Description
+    ------- ------ -----    ------- ------ -----   ---- --  --------            -----------
+    1.8e-70  222.7   3.2      2e-70  222.6   3.2    1.0  1  sp|P02185|MYG_PHYCD  Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2
+    9.2e-69  217.2   0.1      1e-68  217.0   0.1    1.0  1  sp|P02024|HBB_GORGO  Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2
+
+
+Domain annotation for each sequence (and alignments):
+>> sp|P02185|MYG_PHYCD  Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2
+   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
+ ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
+   1 !  222.6   3.2     2e-70     2e-70       2     149 .]       2     148 ..       1     148 [. 0.99
+
+  Alignments for each domain:
+  == domain 1  score: 222.6 bits;  conditional E-value: 2e-70
+             globins4   2 vLseaektkvkavWakveadveesGadiLvrlfkstPatqefFekFkdLstedelkksadvkkHgkkvldAlsdalakldekleaklkdLselHakklkvdpkyfkllsevlvdvlaarlpkeftadvqaaleKllalvakllaskYk 149
+                          vLse+e++ v++vWakveadv+++G+diL+rlfks+P+t+e+F++Fk+L+te+e+k+s+d+kkHg++vl+Al+++l+k ++++ea+lk+L+++Ha+k+k+++ky++++se++++vl++r+p++f+ad+q+a++K+l+l++k++a+kYk
+  sp|P02185|MYG_PHYCD   2 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKK-KGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYK 148
+                          8*****************************************************************************.99******************************************************************7 PP
+
+>> sp|P02024|HBB_GORGO  Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2
+   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
+ ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
+   1 !  217.0   0.1     1e-68     1e-68       1     149 []       2     147 .]       2     147 .] 0.99
+
+  Alignments for each domain:
+  == domain 1  score: 217.0 bits;  conditional E-value: 1e-68
+             globins4   1 vvLseaektkvkavWakveadveesGadiLvrlfkstPatqefFekFkdLstedelkksadvkkHgkkvldAlsdalakldekleaklkdLselHakklkvdpkyfkllsevlvdvlaarlpkeftadvqaaleKllalvakllaskYk 149
+                          v+L+++ek++v+a+W+kv  +v+e+G+++L rl++++P+tq+fFe+F+dLst+d+++++++vk+Hgkkvl+A+sd+la+ld +l++++++LselH++kl+vdp++fkll++vlv+vla++++keft++vqaa++K++a va++la+kY+
+  sp|P02024|HBB_GORGO   2 VHLTPEEKSAVTALWGKV--NVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLD-NLKGTFATLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 147
+                          69****************..*************************************************************.******************************************************************7 PP
+
+
+
+Internal pipeline statistics summary:
+-------------------------------------
+Query model(s):                              1  (149 nodes)
+Target sequences:                            2  (301 residues searched)
+Passed MSV filter:                         2  (1); expected 0.0 (0.02)
+Passed bias filter:                        2  (1); expected 0.0 (0.02)
+Passed Vit filter:                         2  (1); expected 0.0 (0.001)
+Passed Fwd filter:                         2  (1); expected 0.0 (1e-05)
+Initial search space (Z):                  2  [actual number of targets]
+Domain search space  (domZ):               2  [number of targets reported over threshold]
+# CPU time: 0.00u 0.00s 00:00:00.00 Elapsed: 00:00:00.00
+# Mc/sec: inf
+//
+[ok]
b
diff -r 000000000000 -r a6098dd0cb46 test-data/uniprot_matches.fasta
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/uniprot_matches.fasta Sat Jun 25 15:07:32 2016 -0400
b
@@ -0,0 +1,8 @@
+>sp|P02185|MYG_PHYCD Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2
+MVLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASE
+DLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRH
+PGDFGADAQGAMNKALELFRKDIAAKYKELGYQG
+>sp|P02024|HBB_GORGO Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2
+MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK
+VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFKLLGNVLVCVLAHHFG
+KEFTPPVQAAYQKVVAGVANALAHKYH
b
diff -r 000000000000 -r a6098dd0cb46 tool_dependencies.xml
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/tool_dependencies.xml Sat Jun 25 15:07:32 2016 -0400
b
@@ -0,0 +1,6 @@
+<?xml version="1.0"?>
+<tool_dependency>
+  <package name="hmmer" version="3.1b2">
+    <repository changeset_revision="2a1881410dc9" name="package_hmmer_3_1b2" owner="iuc" toolshed="https://toolshed.g2.bx.psu.edu" />
+  </package>
+</tool_dependency>