Metabuli is metagenomic classifier that jointly analyse both DNA and amino acid (AA) sequences. DNA-based classifiers can make specific classifications, exploiting point mutations to distinguish close taxa. AA-based classifiers have higher sensitivity in detecting homology between query and reference sequences, leverageing higher conservation of AA sequences. Metabuli combines the information of both sequence types using a novel k-mer structure, metamer, to enable both specific and sensitive characterization of metagenomic samples. In addition, it can classify reads against a database of any size as long as it fits in the hard disk. |
hg clone https://toolshed.g2.bx.psu.edu/repos/iuc/metabuli
Name | Description | Version | Minimum Galaxy Version |
---|---|---|---|
metagenomic sequences | 1.0.5+galaxy0 | 20.01 |