| Centrifuge is a very rapid and memory-efficient system for the classification of DNA sequences from microbial samples, with better sensitivity than and comparable accuracy to other leading systems. The system uses a novel indexing scheme based on the Burrows-Wheeler transform (BWT) and the Ferragina-Manzini (FM) index, optimized specifically for the metagenomic classification problem. Centrifuge requires a relatively small index (e.g., 4.3 GB for ~4,100 bacterial genomes) yet provides very fast classification speed, allowing it to process a typical DNA sequencing run within an hour. Together these advances enable timely and accurate analysis of large metagenomics data sets on conventional desktop computers. |
hg clone https://toolshed.g2.bx.psu.edu/repos/jvolkening/centrifuge
| Name | Description | Version | Minimum Galaxy Version |
|---|---|---|---|
| Read-based metagenome characterization | 1.0.4_beta | 16.01 | |