Galaxy wrapper for GEMINI
GEMINI: a flexible framework for exploring genome variation
GEMINI (GEnome MINIng) is designed to be a flexible framework for exploring genetic variation in the context of
the wealth of genome annotations available for the human genome. By placing genetic variants, sample genotypes,
and useful genome annotations into an integrated database framework, GEMINI provides a simple, flexible, yet very
powerful system for exploring genetic variation for for disease and population genetics.
Using the GEMINI framework begins by loading a VCF file into a database. Each variant is automatically
annotated by comparing it to several genome annotations from source such as ENCODE tracks, UCSC tracks,
OMIM, dbSNP, KEGG, and HPRD. All of this information is stored in portable SQLite database that allows
one to explore and interpret both coding and non-coding variation using “off-the-shelf” tools or an
enhanced SQL engine.
Please also see the original [manuscript](http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1003153).
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