Mercurial > repos > bimib > cobraxy
changeset 444:06564187fba3 draft
Uploaded
| author | francesco_lapi |
|---|---|
| date | Thu, 11 Sep 2025 09:03:10 +0000 |
| parents | 3d4e10546917 |
| children | c3bb75ce07e6 |
| files | COBRAxy/custom_data_generator_beta.py COBRAxy/custom_data_generator_beta.xml COBRAxy/local/models/ENGRO2.xml COBRAxy/marea_cluster.py COBRAxy/utils/model_utils.py |
| diffstat | 5 files changed, 3596 insertions(+), 3608 deletions(-) [+] |
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--- a/COBRAxy/custom_data_generator_beta.py Wed Sep 10 16:50:16 2025 +0000 +++ b/COBRAxy/custom_data_generator_beta.py Thu Sep 11 09:03:10 2025 +0000 @@ -173,26 +173,26 @@ if value is not None: model.reactions.get_by_id(reaction).lower_bound = -float(value) - if ARGS.name == "ENGRO2" and ARGS.gene_format != "Default": + #if ARGS.name == "ENGRO2" and ARGS.gene_format != "Default": + # logging.basicConfig(level=logging.INFO) + # logger = logging.getLogger(__name__) + + #model = modelUtils.translate_model_genes( + # model=model, + # mapping_df= pd.read_csv(ARGS.tool_dir + "/local/mappings/genes_human.csv"), dtype={'entrez_id': str}, + # target_nomenclature=ARGS.gene_format.replace("HGNC_", "HGNC "), + # source_nomenclature='HGNC_ID', + # logger=logger + #) + #model = modelUtils.convert_genes(model, ARGS.gene_format.replace("HGNC_", "HGNC ")) + + if (ARGS.name == "Recon" or ARGS.name == "ENGRO2") and ARGS.gene_format != "Default": logging.basicConfig(level=logging.INFO) logger = logging.getLogger(__name__) model = modelUtils.translate_model_genes( model=model, - mapping_df= pd.read_csv(ARGS.tool_dir + "/local/mappings/genes_human.csv"), - target_nomenclature=ARGS.gene_format.replace("HGNC_", "HGNC "), - source_nomenclature='HGNC_ID', - logger=logger - ) - #model = modelUtils.convert_genes(model, ARGS.gene_format.replace("HGNC_", "HGNC ")) - - if ARGS.name == "Recon" and ARGS.gene_format != "Default": - logging.basicConfig(level=logging.INFO) - logger = logging.getLogger(__name__) - - model = modelUtils.translate_model_genes( - model=model, - mapping_df= pd.read_csv(ARGS.tool_dir + "/local/mappings/genes_human.csv"), + mapping_df= pd.read_csv(ARGS.tool_dir + "/local/mappings/genes_human.csv", dtype={'entrez_id': str}), target_nomenclature=ARGS.gene_format.replace("HGNC_", "HGNC "), source_nomenclature='HGNC_symbol', logger=logger
--- a/COBRAxy/custom_data_generator_beta.xml Wed Sep 10 16:50:16 2025 +0000 +++ b/COBRAxy/custom_data_generator_beta.xml Thu Sep 11 09:03:10 2025 +0000 @@ -42,9 +42,9 @@ </conditional> <param name="gene_format" argument="--gene_format" type="select" label="Gene nomenclature format:"> - <option value="Default" selected="true">Keep original gene nomenclature (HGNC ID)</option> + <option value="Default" selected="true">Keep original gene nomenclature (HGNC Symbol)</option> <option value="ENSG">ENSNG (Ensembl Gene ID)</option> - <option value="HGNC_symbol">HGNC Symbol</option> + <option value="HGNC_ID">HGNC ID</option> <option value="entrez_id">Entrez Gene ID</option> </param> </when>
--- a/COBRAxy/local/models/ENGRO2.xml Wed Sep 10 16:50:16 2025 +0000 +++ b/COBRAxy/local/models/ENGRO2.xml Thu Sep 11 09:03:10 2025 +0000 @@ -952,9 +952,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10928"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10924"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10922"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC16A7"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC16A3"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC16A1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -1470,11 +1470,11 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4195"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23302"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4922"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4923"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4925"/> + <fbc:geneProductRef fbc:geneProduct="G_GCK"/> + <fbc:geneProductRef fbc:geneProduct="G_HKDC1"/> + <fbc:geneProductRef fbc:geneProduct="G_HK1"/> + <fbc:geneProductRef fbc:geneProduct="G_HK2"/> + <fbc:geneProductRef fbc:geneProduct="G_HK3"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -1505,9 +1505,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4056"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__24861"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__28906"/> + <fbc:geneProductRef fbc:geneProduct="G_G6PC1"/> + <fbc:geneProductRef fbc:geneProduct="G_G6PC3"/> + <fbc:geneProductRef fbc:geneProduct="G_G6PC2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -1536,7 +1536,7 @@ <speciesReference species="M_f6p_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4458"/> + <fbc:geneProductRef fbc:geneProduct="G_GPI"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PFK" sboTerm="SBO:0000176" id="R_PFK" name="PFK1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -1568,9 +1568,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8878"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8876"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8877"/> + <fbc:geneProductRef fbc:geneProduct="G_PFKP"/> + <fbc:geneProductRef fbc:geneProduct="G_PFKL"/> + <fbc:geneProductRef fbc:geneProduct="G_PFKM"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -1601,8 +1601,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3607"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3606"/> + <fbc:geneProductRef fbc:geneProduct="G_FBP2"/> + <fbc:geneProductRef fbc:geneProduct="G_FBP1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -1633,9 +1633,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__418"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__417"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__414"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDOC"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDOB"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDOA"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -1664,7 +1664,7 @@ <speciesReference species="M_g3p_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12009"/> + <fbc:geneProductRef fbc:geneProduct="G_TPI1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_GAPD" sboTerm="SBO:0000176" id="R_GAPD" name="GAPDH" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -1697,8 +1697,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__24864"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4141"/> + <fbc:geneProductRef fbc:geneProduct="G_GAPDHS"/> + <fbc:geneProductRef fbc:geneProduct="G_GAPDH"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -1730,8 +1730,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8896"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8898"/> + <fbc:geneProductRef fbc:geneProduct="G_PGK1"/> + <fbc:geneProductRef fbc:geneProduct="G_PGK2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -1761,9 +1761,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8889"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8888"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1093"/> + <fbc:geneProductRef fbc:geneProduct="G_PGAM2"/> + <fbc:geneProductRef fbc:geneProduct="G_PGAM1"/> + <fbc:geneProductRef fbc:geneProduct="G_BPGM"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -1794,9 +1794,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8889"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8888"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1093"/> + <fbc:geneProductRef fbc:geneProduct="G_PGAM2"/> + <fbc:geneProductRef fbc:geneProduct="G_PGAM1"/> + <fbc:geneProductRef fbc:geneProduct="G_BPGM"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -1826,9 +1826,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8889"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8888"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1093"/> + <fbc:geneProductRef fbc:geneProduct="G_PGAM2"/> + <fbc:geneProductRef fbc:geneProduct="G_PGAM1"/> + <fbc:geneProductRef fbc:geneProduct="G_BPGM"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -1859,9 +1859,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3350"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3354"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3353"/> + <fbc:geneProductRef fbc:geneProduct="G_ENO1"/> + <fbc:geneProductRef fbc:geneProduct="G_ENO3"/> + <fbc:geneProductRef fbc:geneProduct="G_ENO2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -1894,8 +1894,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9021"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9020"/> + <fbc:geneProductRef fbc:geneProduct="G_PKM"/> + <fbc:geneProductRef fbc:geneProduct="G_PKLR"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -1927,12 +1927,12 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6541"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6535"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30866"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6544"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__28335"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21481"/> + <fbc:geneProductRef fbc:geneProduct="G_LDHB"/> + <fbc:geneProductRef fbc:geneProduct="G_LDHA"/> + <fbc:geneProductRef fbc:geneProduct="G_UEVLD"/> + <fbc:geneProductRef fbc:geneProduct="G_LDHC"/> + <fbc:geneProductRef fbc:geneProduct="G_LDHAL6A"/> + <fbc:geneProductRef fbc:geneProduct="G_LDHAL6B"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -1962,9 +1962,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__418"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__417"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__414"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDOC"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDOB"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDOA"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -1996,9 +1996,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9465"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9462"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9463"/> + <fbc:geneProductRef fbc:geneProduct="G_PRPS2"/> + <fbc:geneProductRef fbc:geneProduct="G_PRPS1"/> + <fbc:geneProductRef fbc:geneProduct="G_PRPS1L1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -2029,7 +2029,7 @@ <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4057"/> + <fbc:geneProductRef fbc:geneProduct="G_G6PD"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PGL" sboTerm="SBO:0000176" id="R_PGL" name="PGLS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -2059,8 +2059,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4795"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8903"/> + <fbc:geneProductRef fbc:geneProduct="G_H6PD"/> + <fbc:geneProductRef fbc:geneProduct="G_PGLS"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -2091,7 +2091,7 @@ <speciesReference species="M_ru5p__D_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8891"/> + <fbc:geneProductRef fbc:geneProduct="G_PGD"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_RPI" sboTerm="SBO:0000176" id="R_RPI" name="RPI" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -2118,7 +2118,7 @@ <speciesReference species="M_r5p_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10297"/> + <fbc:geneProductRef fbc:geneProduct="G_RPIA"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_TKT2" sboTerm="SBO:0000176" id="R_TKT2" name="TKT1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -2148,9 +2148,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11835"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__25313"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11834"/> + <fbc:geneProductRef fbc:geneProduct="G_TKTL1"/> + <fbc:geneProductRef fbc:geneProduct="G_TKTL2"/> + <fbc:geneProductRef fbc:geneProduct="G_TKT"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -2179,8 +2179,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10293"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__45241"/> + <fbc:geneProductRef fbc:geneProduct="G_RPE"/> + <fbc:geneProductRef fbc:geneProduct="G_RPEL1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -2211,9 +2211,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11835"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__25313"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11834"/> + <fbc:geneProductRef fbc:geneProduct="G_TKTL1"/> + <fbc:geneProductRef fbc:geneProduct="G_TKTL2"/> + <fbc:geneProductRef fbc:geneProduct="G_TKT"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -2243,7 +2243,7 @@ <speciesReference species="M_f6p_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11559"/> + <fbc:geneProductRef fbc:geneProduct="G_TALDO1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0408" sboTerm="SBO:0000176" id="R_r0408" name="SBPase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -2274,9 +2274,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8878"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8876"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8877"/> + <fbc:geneProductRef fbc:geneProduct="G_PFKP"/> + <fbc:geneProductRef fbc:geneProduct="G_PFKL"/> + <fbc:geneProductRef fbc:geneProduct="G_PFKM"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -2309,13 +2309,13 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2898"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21350"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2896"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8808"/> + <fbc:geneProductRef fbc:geneProduct="G_DLD"/> + <fbc:geneProductRef fbc:geneProduct="G_PDHX"/> + <fbc:geneProductRef fbc:geneProduct="G_DLAT"/> + <fbc:geneProductRef fbc:geneProduct="G_PDHB"/> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8806"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8807"/> + <fbc:geneProductRef fbc:geneProduct="G_PDHA1"/> + <fbc:geneProductRef fbc:geneProduct="G_PDHA2"/> </fbc:or> </fbc:and> </fbc:geneProductAssociation> @@ -2349,7 +2349,7 @@ <speciesReference species="M_pi_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8636"/> + <fbc:geneProductRef fbc:geneProduct="G_PC"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PEPCK_re" sboTerm="SBO:0000176" id="R_PEPCK_re" name="PEPCK" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -2379,7 +2379,7 @@ <speciesReference species="M_pep_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8724"/> + <fbc:geneProductRef fbc:geneProduct="G_PCK1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_CSm" sboTerm="SBO:0000176" id="R_CSm" name="CS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -2410,7 +2410,7 @@ <speciesReference species="M_h_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2422"/> + <fbc:geneProductRef fbc:geneProduct="G_CS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ACONTm" sboTerm="SBO:0000176" id="R_ACONTm" name="mACO" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -2438,8 +2438,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__118"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__117"/> + <fbc:geneProductRef fbc:geneProduct="G_ACO2"/> + <fbc:geneProductRef fbc:geneProduct="G_ACO1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -2471,9 +2471,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5386"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5385"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5384"/> + <fbc:geneProductRef fbc:geneProduct="G_IDH3G"/> + <fbc:geneProductRef fbc:geneProduct="G_IDH3B"/> + <fbc:geneProductRef fbc:geneProduct="G_IDH3A"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -2504,7 +2504,7 @@ <speciesReference species="M_nadph_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5383"/> + <fbc:geneProductRef fbc:geneProduct="G_IDH2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_AKGDm" sboTerm="SBO:0000176" id="R_AKGDm" name="AKGDH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -2536,9 +2536,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2898"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8124"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2911"/> + <fbc:geneProductRef fbc:geneProduct="G_DLD"/> + <fbc:geneProductRef fbc:geneProduct="G_OGDH"/> + <fbc:geneProductRef fbc:geneProduct="G_DLST"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -2571,8 +2571,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11449"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11450"/> + <fbc:geneProductRef fbc:geneProduct="G_SUCLG1"/> + <fbc:geneProductRef fbc:geneProduct="G_SUCLG2"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -2603,10 +2603,10 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10680"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10681"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10682"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10683"/> + <fbc:geneProductRef fbc:geneProduct="G_SDHA"/> + <fbc:geneProductRef fbc:geneProduct="G_SDHB"/> + <fbc:geneProductRef fbc:geneProduct="G_SDHC"/> + <fbc:geneProductRef fbc:geneProduct="G_SDHD"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -2635,7 +2635,7 @@ <speciesReference species="M_mal__L_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3700"/> + <fbc:geneProductRef fbc:geneProduct="G_FH"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_MDHm" sboTerm="SBO:0000176" id="R_MDHm" name="MDH2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -2665,7 +2665,7 @@ <speciesReference species="M_oaa_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6971"/> + <fbc:geneProductRef fbc:geneProduct="G_MDH2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ME1m" sboTerm="SBO:0000176" id="R_ME1m" name="ME2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -2695,7 +2695,7 @@ <speciesReference species="M_pyr_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6984"/> + <fbc:geneProductRef fbc:geneProduct="G_ME2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ME2m" sboTerm="SBO:0000176" id="R_ME2m" name="ME3" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -2725,7 +2725,7 @@ <speciesReference species="M_pyr_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6985"/> + <fbc:geneProductRef fbc:geneProduct="G_ME3"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ME2" sboTerm="SBO:0000176" id="R_ME2" name="ME1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -2755,7 +2755,7 @@ <speciesReference species="M_pyr_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6983"/> + <fbc:geneProductRef fbc:geneProduct="G_ME1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ACITL" sboTerm="SBO:0000176" id="R_ACITL" name="ACLY" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -2787,7 +2787,7 @@ <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__115"/> + <fbc:geneProductRef fbc:geneProduct="G_ACLY"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_FUM" sboTerm="SBO:0000176" id="R_FUM" name="FH2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -2815,7 +2815,7 @@ <speciesReference species="M_mal__L_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3700"/> + <fbc:geneProductRef fbc:geneProduct="G_FH"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_MDH" sboTerm="SBO:0000176" id="R_MDH" name="MDH1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -2846,8 +2846,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6970"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17836"/> + <fbc:geneProductRef fbc:geneProduct="G_MDH1"/> + <fbc:geneProductRef fbc:geneProduct="G_MDH1B"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -2878,8 +2878,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10981"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10980"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A11"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A10"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -2907,7 +2907,7 @@ <speciesReference species="M_icit_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__117"/> + <fbc:geneProductRef fbc:geneProduct="G_ACO1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ICDHyr" sboTerm="SBO:0000176" id="R_ICDHyr" name="IDH1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -2937,7 +2937,7 @@ <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5382"/> + <fbc:geneProductRef fbc:geneProduct="G_IDH1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PPA" sboTerm="SBO:0000176" id="R_PPA" name="cPPA" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -2967,8 +2967,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30042"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9226"/> + <fbc:geneProductRef fbc:geneProduct="G_LHPP"/> + <fbc:geneProductRef fbc:geneProduct="G_PPA1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -3003,45 +3003,45 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7694"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7707"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7699"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7697"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7702"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7705"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7715"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7714"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7698"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7692"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7683"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7688"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7684"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7685"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7700"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7693"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7696"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20372"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7704"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7706"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7708"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7701"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7703"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7716"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7712"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7686"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20371"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7717"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7695"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7690"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17194"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7462"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7456"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7461"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7458"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7459"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7455"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7460"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7710"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFAB1"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFS1"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFB4"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFB2"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFB7"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFC1"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFS8"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFS7"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFB3"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFA8"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFA1"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFA5"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFA10"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFA2"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFB5"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFA9"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFB10"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFB11"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFB9"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFC2"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFS2"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFB6"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFB8"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFV1"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFS5"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFA3"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFA11"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFV2"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFB1"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFA6"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFA13"/> + <fbc:geneProductRef fbc:geneProduct="G_MT__45__ND6"/> + <fbc:geneProductRef fbc:geneProduct="G_MT__45__ND2"/> + <fbc:geneProductRef fbc:geneProduct="G_MT__45__ND5"/> + <fbc:geneProductRef fbc:geneProduct="G_MT__45__ND3"/> + <fbc:geneProductRef fbc:geneProduct="G_MT__45__ND4"/> + <fbc:geneProductRef fbc:geneProduct="G_MT__45__ND1"/> + <fbc:geneProductRef fbc:geneProduct="G_MT__45__ND4L"/> + <fbc:geneProductRef fbc:geneProduct="G_NDUFS3"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -3072,9 +3072,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3483"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3482"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3481"/> + <fbc:geneProductRef fbc:geneProduct="G_ETFDH"/> + <fbc:geneProductRef fbc:geneProduct="G_ETFB"/> + <fbc:geneProductRef fbc:geneProduct="G_ETFA"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -3107,16 +3107,16 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12585"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30862"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12586"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12582"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29594"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12587"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12590"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2579"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30863"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7427"/> + <fbc:geneProductRef fbc:geneProduct="G_UQCRC1"/> + <fbc:geneProductRef fbc:geneProduct="G_UQCR11"/> + <fbc:geneProductRef fbc:geneProduct="G_UQCRC2"/> + <fbc:geneProductRef fbc:geneProduct="G_UQCRB"/> + <fbc:geneProductRef fbc:geneProduct="G_UQCRQ"/> + <fbc:geneProductRef fbc:geneProduct="G_UQCRFS1"/> + <fbc:geneProductRef fbc:geneProduct="G_UQCRH"/> + <fbc:geneProductRef fbc:geneProduct="G_CYC1"/> + <fbc:geneProductRef fbc:geneProduct="G_UQCR10"/> + <fbc:geneProductRef fbc:geneProduct="G_MT__45__CYB"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -3149,36 +3149,36 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2292"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2269"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2285"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2267"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7421"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7419"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7422"/> + <fbc:geneProductRef fbc:geneProduct="G_COX7C"/> + <fbc:geneProductRef fbc:geneProduct="G_COX5B"/> + <fbc:geneProductRef fbc:geneProduct="G_COX6C"/> + <fbc:geneProductRef fbc:geneProduct="G_COX5A"/> + <fbc:geneProductRef fbc:geneProduct="G_MT__45__CO2"/> + <fbc:geneProductRef fbc:geneProduct="G_MT__45__CO1"/> + <fbc:geneProductRef fbc:geneProduct="G_MT__45__CO3"/> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2277"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2279"/> + <fbc:geneProductRef fbc:geneProduct="G_COX6A1"/> + <fbc:geneProductRef fbc:geneProduct="G_COX6A2"/> </fbc:or> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2288"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2287"/> + <fbc:geneProductRef fbc:geneProduct="G_COX7A2"/> + <fbc:geneProductRef fbc:geneProduct="G_COX7A1"/> </fbc:or> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2280"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__24380"/> + <fbc:geneProductRef fbc:geneProduct="G_COX6B1"/> + <fbc:geneProductRef fbc:geneProduct="G_COX6B2"/> </fbc:or> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__16232"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2265"/> + <fbc:geneProductRef fbc:geneProduct="G_COX4I2"/> + <fbc:geneProductRef fbc:geneProduct="G_COX4I1"/> </fbc:or> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2291"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__24381"/> + <fbc:geneProductRef fbc:geneProduct="G_COX7B"/> + <fbc:geneProductRef fbc:geneProduct="G_COX7B2"/> </fbc:or> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2294"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__24382"/> + <fbc:geneProductRef fbc:geneProduct="G_COX8A"/> + <fbc:geneProductRef fbc:geneProduct="G_COX8C"/> </fbc:or> </fbc:and> </fbc:geneProductAssociation> @@ -3212,24 +3212,24 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__837"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__830"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__840"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__838"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__823"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__847"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__833"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14247"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__845"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__846"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7414"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7415"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__848"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__850"/> + <fbc:geneProductRef fbc:geneProduct="G_ATP5F1D"/> + <fbc:geneProductRef fbc:geneProduct="G_ATP5F1B"/> + <fbc:geneProductRef fbc:geneProduct="G_ATP5PB"/> + <fbc:geneProductRef fbc:geneProduct="G_ATP5F1E"/> + <fbc:geneProductRef fbc:geneProduct="G_ATP5F1A"/> + <fbc:geneProductRef fbc:geneProduct="G_ATP5PF"/> + <fbc:geneProductRef fbc:geneProduct="G_ATP5F1C"/> + <fbc:geneProductRef fbc:geneProduct="G_ATP5MG"/> + <fbc:geneProductRef fbc:geneProduct="G_ATP5PD"/> + <fbc:geneProductRef fbc:geneProduct="G_ATP5ME"/> + <fbc:geneProductRef fbc:geneProduct="G_MT__45__ATP6"/> + <fbc:geneProductRef fbc:geneProduct="G_MT__45__ATP8"/> + <fbc:geneProductRef fbc:geneProduct="G_ATP5MF"/> + <fbc:geneProductRef fbc:geneProduct="G_ATP5PO"/> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__842"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__843"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__841"/> + <fbc:geneProductRef fbc:geneProduct="G_ATP5MC2"/> + <fbc:geneProductRef fbc:geneProduct="G_ATP5MC3"/> + <fbc:geneProductRef fbc:geneProduct="G_ATP5MC1"/> </fbc:or> </fbc:and> </fbc:geneProductAssociation> @@ -3264,8 +3264,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4311"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4312"/> + <fbc:geneProductRef fbc:geneProduct="G_GCLC"/> + <fbc:geneProductRef fbc:geneProduct="G_GCLM"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -3298,7 +3298,7 @@ <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4624"/> + <fbc:geneProductRef fbc:geneProduct="G_GSS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_SPODMm" sboTerm="SBO:0000176" id="R_SPODMm" name="SOD2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -3327,7 +3327,7 @@ <speciesReference species="M_o2_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11180"/> + <fbc:geneProductRef fbc:geneProduct="G_SOD2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_GTHPi" sboTerm="SBO:0000176" id="R_GTHPi" name="GPcit" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -3357,11 +3357,11 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9352"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4556"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9353"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4554"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4553"/> + <fbc:geneProductRef fbc:geneProduct="G_PRDX1"/> + <fbc:geneProductRef fbc:geneProduct="G_GPX4"/> + <fbc:geneProductRef fbc:geneProduct="G_PRDX2"/> + <fbc:geneProductRef fbc:geneProduct="G_GPX2"/> + <fbc:geneProductRef fbc:geneProduct="G_GPX1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -3392,9 +3392,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9354"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4556"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4553"/> + <fbc:geneProductRef fbc:geneProduct="G_PRDX3"/> + <fbc:geneProductRef fbc:geneProduct="G_GPX4"/> + <fbc:geneProductRef fbc:geneProduct="G_GPX1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -3425,7 +3425,7 @@ <speciesReference species="M_nad_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4623"/> + <fbc:geneProductRef fbc:geneProduct="G_GSR"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_GTHOr" sboTerm="SBO:0000176" id="R_GTHOr" name="cGSRnadph" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -3455,7 +3455,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4623"/> + <fbc:geneProductRef fbc:geneProduct="G_GSR"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_GDRm" sboTerm="SBO:0000176" id="R_GDRm" name="mGSRnadh" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -3485,7 +3485,7 @@ <speciesReference species="M_nad_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4623"/> + <fbc:geneProductRef fbc:geneProduct="G_GSR"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_GTHOm" sboTerm="SBO:0000176" id="R_GTHOm" name="mGSRnadph" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -3515,7 +3515,7 @@ <speciesReference species="M_nadp_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4623"/> + <fbc:geneProductRef fbc:geneProduct="G_GSR"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0885" sboTerm="SBO:0000176" id="R_r0885" name="TrasportGSH" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -3544,7 +3544,7 @@ <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10980"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A10"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PYRt2m" sboTerm="SBO:0000176" id="R_PYRt2m" name="MPC" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -3574,9 +3574,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21606"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__24515"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10922"/> + <fbc:geneProductRef fbc:geneProduct="G_MPC1"/> + <fbc:geneProductRef fbc:geneProduct="G_MPC2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC16A1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -3608,7 +3608,7 @@ <speciesReference species="M_mal__L_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10979"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r2420" sboTerm="SBO:0000176" id="R_r2420" name="SLC25A2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -3637,7 +3637,7 @@ <speciesReference species="M_pi_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10989"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A3"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ATPtm" sboTerm="SBO:0000176" id="R_ATPtm" name="ANT" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -3667,9 +3667,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10991"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10990"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10992"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A4"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A6"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -3699,7 +3699,7 @@ <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10980"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A10"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_CO2tm" sboTerm="SBO:0000176" id="R_CO2tm" name="TransportCO2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -3776,7 +3776,7 @@ <speciesReference species="M_gtp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10992"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A6"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_THD1m" sboTerm="SBO:0000176" id="R_THD1m" name="NNT" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -3807,7 +3807,7 @@ <speciesReference species="M_nadph_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7863"/> + <fbc:geneProductRef fbc:geneProduct="G_NNT"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_H2Otm" sboTerm="SBO:0000176" id="R_H2Otm" name="AQP8" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -3834,7 +3834,7 @@ <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__642"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP8"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_NH4tm" sboTerm="SBO:0000176" id="R_NH4tm" name="TransportNH3" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -3888,16 +3888,16 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1371"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1373"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1383"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1372"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1380"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1368"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1374"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1375"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1381"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14914"/> + <fbc:geneProductRef fbc:geneProduct="G_CA12"/> + <fbc:geneProductRef fbc:geneProduct="G_CA2"/> + <fbc:geneProductRef fbc:geneProduct="G_CA9"/> + <fbc:geneProductRef fbc:geneProduct="G_CA14"/> + <fbc:geneProductRef fbc:geneProduct="G_CA6"/> + <fbc:geneProductRef fbc:geneProduct="G_CA1"/> + <fbc:geneProductRef fbc:geneProduct="G_CA3"/> + <fbc:geneProductRef fbc:geneProduct="G_CA4"/> + <fbc:geneProductRef fbc:geneProduct="G_CA7"/> + <fbc:geneProductRef fbc:geneProduct="G_CA13"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -3928,8 +3928,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1378"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1377"/> + <fbc:geneProductRef fbc:geneProduct="G_CA5B"/> + <fbc:geneProductRef fbc:geneProduct="G_CA5A"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -3959,7 +3959,7 @@ <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4331"/> + <fbc:geneProductRef fbc:geneProduct="G_GLS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_GLNS" sboTerm="SBO:0000176" id="R_GLNS" name="GS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -3992,8 +3992,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4341"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21016"/> + <fbc:geneProductRef fbc:geneProduct="G_GLUL"/> + <fbc:geneProductRef fbc:geneProduct="G_LGSN"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -4024,8 +4024,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19954"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10988"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A22"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A18"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -4082,8 +4082,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4331"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29570"/> + <fbc:geneProductRef fbc:geneProduct="G_GLS"/> + <fbc:geneProductRef fbc:geneProduct="G_GLS2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -4115,7 +4115,7 @@ <speciesReference species="M_pram_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9238"/> + <fbc:geneProductRef fbc:geneProduct="G_PPAT"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PRAGSr" sboTerm="SBO:0000176" id="R_PRAGSr" name="GART1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -4147,7 +4147,7 @@ <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4163"/> + <fbc:geneProductRef fbc:geneProduct="G_GART"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_GARFT" sboTerm="SBO:0000176" id="R_GARFT" name="GART2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -4177,7 +4177,7 @@ <speciesReference species="M_thf_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4163"/> + <fbc:geneProductRef fbc:geneProduct="G_GART"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PRFGS" sboTerm="SBO:0000176" id="R_PRFGS" name="PFAS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -4211,7 +4211,7 @@ <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8863"/> + <fbc:geneProductRef fbc:geneProduct="G_PFAS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PRAIS" sboTerm="SBO:0000176" id="R_PRAIS" name="GART3" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -4242,7 +4242,7 @@ <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4163"/> + <fbc:geneProductRef fbc:geneProduct="G_GART"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_AIRCr" sboTerm="SBO:0000176" id="R_AIRCr" name="PAICS1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -4271,7 +4271,7 @@ <speciesReference species="M_h_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8587"/> + <fbc:geneProductRef fbc:geneProduct="G_PAICS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PRASCSi" sboTerm="SBO:0000176" id="R_PRASCSi" name="PAICS2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -4303,7 +4303,7 @@ <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8587"/> + <fbc:geneProductRef fbc:geneProduct="G_PAICS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ADSL2r" sboTerm="SBO:0000176" id="R_ADSL2r" name="PAICS3" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -4331,7 +4331,7 @@ <speciesReference species="M_fum_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__291"/> + <fbc:geneProductRef fbc:geneProduct="G_ADSL"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_AICART" sboTerm="SBO:0000176" id="R_AICART" name="ATIC1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -4360,7 +4360,7 @@ <speciesReference species="M_thf_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__794"/> + <fbc:geneProductRef fbc:geneProduct="G_ATIC"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_IMPC" sboTerm="SBO:0000176" id="R_IMPC" name="ATIC2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -4388,7 +4388,7 @@ <speciesReference species="M_imp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__794"/> + <fbc:geneProductRef fbc:geneProduct="G_ATIC"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ADSS" sboTerm="SBO:0000176" id="R_ADSS" name="ADSS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -4421,8 +4421,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__292"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20093"/> + <fbc:geneProductRef fbc:geneProduct="G_ADSS2"/> + <fbc:geneProductRef fbc:geneProduct="G_ADSS1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -4451,7 +4451,7 @@ <speciesReference species="M_fum_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__291"/> + <fbc:geneProductRef fbc:geneProduct="G_ADSL"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_IMPDH2" sboTerm="SBO:0000176" id="R_IMPDH2" name="IMPDH2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -4483,8 +4483,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6052"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6053"/> + <fbc:geneProductRef fbc:geneProduct="G_IMPDH1"/> + <fbc:geneProductRef fbc:geneProduct="G_IMPDH2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -4517,7 +4517,7 @@ <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4378"/> + <fbc:geneProductRef fbc:geneProduct="G_GMPS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_GMPS2" sboTerm="SBO:0000176" id="R_GMPS2" name="GMPS2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -4551,7 +4551,7 @@ <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4378"/> + <fbc:geneProductRef fbc:geneProduct="G_GMPS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_GK1" sboTerm="SBO:0000176" id="R_GK1" name="GUK1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -4580,7 +4580,7 @@ <speciesReference species="M_gdp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4693"/> + <fbc:geneProductRef fbc:geneProduct="G_GUK1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_RNDR2" sboTerm="SBO:0000176" id="R_RNDR2" name="RRM2B1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -4609,10 +4609,10 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10451"/> + <fbc:geneProductRef fbc:geneProduct="G_RRM1"/> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17296"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10452"/> + <fbc:geneProductRef fbc:geneProduct="G_RRM2B"/> + <fbc:geneProductRef fbc:geneProduct="G_RRM2"/> </fbc:or> </fbc:and> </fbc:geneProductAssociation> @@ -4643,10 +4643,10 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__362"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__361"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20091"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__365"/> + <fbc:geneProductRef fbc:geneProduct="G_AK2"/> + <fbc:geneProductRef fbc:geneProduct="G_AK1"/> + <fbc:geneProductRef fbc:geneProduct="G_AK7"/> + <fbc:geneProductRef fbc:geneProduct="G_AK5"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -4676,10 +4676,10 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10451"/> + <fbc:geneProductRef fbc:geneProduct="G_RRM1"/> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17296"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10452"/> + <fbc:geneProductRef fbc:geneProduct="G_RRM2B"/> + <fbc:geneProductRef fbc:geneProduct="G_RRM2"/> </fbc:or> </fbc:and> </fbc:geneProductAssociation> @@ -4715,7 +4715,7 @@ <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1424"/> + <fbc:geneProductRef fbc:geneProduct="G_CAD"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ASPCT" sboTerm="SBO:0000176" id="R_ASPCT" name="CAD2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -4745,7 +4745,7 @@ <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1424"/> + <fbc:geneProductRef fbc:geneProduct="G_CAD"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_DHORTS" sboTerm="SBO:0000176" id="R_DHORTS" name="CAD3" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -4774,7 +4774,7 @@ <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1424"/> + <fbc:geneProductRef fbc:geneProduct="G_CAD"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_DHORD9" sboTerm="SBO:0000176" id="R_DHORD9" name="DHODH" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -4803,7 +4803,7 @@ <speciesReference species="M_q10h2_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2867"/> + <fbc:geneProductRef fbc:geneProduct="G_DHODH"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ORPT" sboTerm="SBO:0000176" id="R_ORPT" name="UMPS1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -4832,7 +4832,7 @@ <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12563"/> + <fbc:geneProductRef fbc:geneProduct="G_UMPS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_OMPDC" sboTerm="SBO:0000176" id="R_OMPDC" name="UMPS2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -4861,7 +4861,7 @@ <speciesReference species="M_ump_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12563"/> + <fbc:geneProductRef fbc:geneProduct="G_UMPS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_UMPK" sboTerm="SBO:0000176" id="R_UMPK" name="CMPK1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -4890,7 +4890,7 @@ <speciesReference species="M_udp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18170"/> + <fbc:geneProductRef fbc:geneProduct="G_CMPK1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_RNDR4" sboTerm="SBO:0000176" id="R_RNDR4" name="RRM2B3" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -4919,10 +4919,10 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10451"/> + <fbc:geneProductRef fbc:geneProduct="G_RRM1"/> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17296"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10452"/> + <fbc:geneProductRef fbc:geneProduct="G_RRM2B"/> + <fbc:geneProductRef fbc:geneProduct="G_RRM2"/> </fbc:or> </fbc:and> </fbc:geneProductAssociation> @@ -4953,7 +4953,7 @@ <speciesReference species="M_dtmp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12441"/> + <fbc:geneProductRef fbc:geneProduct="G_TYMS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_URIDK2r" sboTerm="SBO:0000176" id="R_URIDK2r" name="CMPK2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -4982,7 +4982,7 @@ <speciesReference species="M_dump_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3061"/> + <fbc:geneProductRef fbc:geneProduct="G_DTYMK"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_NDPK2" sboTerm="SBO:0000176" id="R_NDPK2" name="NME1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -5012,12 +5012,12 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7851"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20461"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20567"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7849"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7850"/> + <fbc:geneProductRef fbc:geneProduct="G_NME3"/> + <fbc:geneProductRef fbc:geneProduct="G_NME7"/> + <fbc:geneProductRef fbc:geneProduct="G_NME6"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_NME1"/> + <fbc:geneProductRef fbc:geneProduct="G_NME2"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -5049,12 +5049,12 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7851"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20461"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20567"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7849"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7850"/> + <fbc:geneProductRef fbc:geneProduct="G_NME3"/> + <fbc:geneProductRef fbc:geneProduct="G_NME7"/> + <fbc:geneProductRef fbc:geneProduct="G_NME6"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_NME1"/> + <fbc:geneProductRef fbc:geneProduct="G_NME2"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -5089,8 +5089,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2520"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2519"/> + <fbc:geneProductRef fbc:geneProduct="G_CTPS2"/> + <fbc:geneProductRef fbc:geneProduct="G_CTPS1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -5120,10 +5120,10 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10451"/> + <fbc:geneProductRef fbc:geneProduct="G_RRM1"/> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17296"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10452"/> + <fbc:geneProductRef fbc:geneProduct="G_RRM2B"/> + <fbc:geneProductRef fbc:geneProduct="G_RRM2"/> </fbc:or> </fbc:and> </fbc:geneProductAssociation> @@ -5158,8 +5158,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4335"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4336"/> + <fbc:geneProductRef fbc:geneProduct="G_GLUD1"/> + <fbc:geneProductRef fbc:geneProduct="G_GLUD2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -5193,8 +5193,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4335"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4336"/> + <fbc:geneProductRef fbc:geneProduct="G_GLUD1"/> + <fbc:geneProductRef fbc:geneProduct="G_GLUD2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -5224,7 +5224,7 @@ <speciesReference species="M_oaa_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4432"/> + <fbc:geneProductRef fbc:geneProduct="G_GOT1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ASPTAm" sboTerm="SBO:0000176" id="R_ASPTAm" name="mGOT" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -5253,7 +5253,7 @@ <speciesReference species="M_asp__L_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4433"/> + <fbc:geneProductRef fbc:geneProduct="G_GOT2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ASPGLUm" sboTerm="SBO:0000176" id="R_ASPGLUm" name="GLAST" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -5285,8 +5285,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10983"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10982"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A13"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A12"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -5315,7 +5315,7 @@ <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3700"/> + <fbc:geneProductRef fbc:geneProduct="G_FH"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_CBPSam" sboTerm="SBO:0000176" id="R_CBPSam" name="CPS1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -5347,7 +5347,7 @@ <speciesReference species="M_pi_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2323"/> + <fbc:geneProductRef fbc:geneProduct="G_CPS1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_OCBTm" sboTerm="SBO:0000176" id="R_OCBTm" name="OTC" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -5377,7 +5377,7 @@ <speciesReference species="M_pi_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8512"/> + <fbc:geneProductRef fbc:geneProduct="G_OTC"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ORNt4m" sboTerm="SBO:0000176" id="R_ORNt4m" name="ORNT" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -5409,8 +5409,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10985"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__22921"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A15"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -5443,7 +5443,7 @@ <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__758"/> + <fbc:geneProductRef fbc:geneProduct="G_ASS1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ARGSL" sboTerm="SBO:0000176" id="R_ARGSL" name="ASL" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -5471,7 +5471,7 @@ <speciesReference species="M_fum_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__746"/> + <fbc:geneProductRef fbc:geneProduct="G_ASL"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ARGN" sboTerm="SBO:0000176" id="R_ARGN" name="ARG1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -5500,7 +5500,7 @@ <speciesReference species="M_urea_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__663"/> + <fbc:geneProductRef fbc:geneProduct="G_ARG1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ORNDC" sboTerm="SBO:0000176" id="R_ORNDC" name="ODC1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -5529,7 +5529,7 @@ <speciesReference species="M_ptrc_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8109"/> + <fbc:geneProductRef fbc:geneProduct="G_ODC1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_SPMS" sboTerm="SBO:0000176" id="R_SPMS" name="SpermidineSynthase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -5559,7 +5559,7 @@ <speciesReference species="M_spmd_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11296"/> + <fbc:geneProductRef fbc:geneProduct="G_SRM"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_SPRMS" sboTerm="SBO:0000176" id="R_SPRMS" name="SpermineSynthase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -5590,8 +5590,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11123"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11296"/> + <fbc:geneProductRef fbc:geneProduct="G_SMS"/> + <fbc:geneProductRef fbc:geneProduct="G_SRM"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -5621,7 +5621,7 @@ <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__457"/> + <fbc:geneProductRef fbc:geneProduct="G_AMD1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_MTAP" sboTerm="SBO:0000176" id="R_MTAP" name="MTAP" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -5650,7 +5650,7 @@ <speciesReference species="M_ade_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7413"/> + <fbc:geneProductRef fbc:geneProduct="G_MTAP"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ADPT" sboTerm="SBO:0000176" id="R_ADPT" name="APRT" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -5679,7 +5679,7 @@ <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__626"/> + <fbc:geneProductRef fbc:geneProduct="G_APRT"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_MTRI" sboTerm="SBO:0000176" id="R_MTRI" name="MRI1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -5732,12 +5732,12 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__642"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7103"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__638"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__634"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__637"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__633"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP8"/> + <fbc:geneProductRef fbc:geneProduct="G_MIP"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP5"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP2"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP4"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -5818,7 +5818,7 @@ <speciesReference species="M_sprm_e" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10963"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC22A1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_GLYAMDTRc" sboTerm="SBO:0000176" id="R_GLYAMDTRc" name="AGAT" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -5847,7 +5847,7 @@ <speciesReference species="M_orn_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4175"/> + <fbc:geneProductRef fbc:geneProduct="G_GATM"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ARGDr" sboTerm="SBO:0000176" id="R_ARGDr" name="ARGAH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -5904,7 +5904,7 @@ <speciesReference species="M_nad_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__406"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDH4A1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_GLU5SAtmc" sboTerm="SBO:0000176" id="R_GLU5SAtmc" name="TransportGLU5SA" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -5957,7 +5957,7 @@ <speciesReference species="M_h_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__406"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDH4A1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PRO1x" sboTerm="SBO:0000176" id="R_PRO1x" name="P5CR2nadh" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -5987,7 +5987,7 @@ <speciesReference species="M_pro__L_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30262"/> + <fbc:geneProductRef fbc:geneProduct="G_PYCR2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_P5CR" sboTerm="SBO:0000176" id="R_P5CR" name="P5CR2nadph" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -6017,7 +6017,7 @@ <speciesReference species="M_pro__L_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30262"/> + <fbc:geneProductRef fbc:geneProduct="G_PYCR2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PROD2" sboTerm="SBO:0000176" id="R_PROD2" name="PRODH2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -6047,7 +6047,7 @@ <speciesReference species="M_h_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17325"/> + <fbc:geneProductRef fbc:geneProduct="G_PRODH2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_TransportFAD" sboTerm="SBO:0000176" id="R_TransportFAD" name="TransportFAD" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -6107,7 +6107,7 @@ <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__753"/> + <fbc:geneProductRef fbc:geneProduct="G_ASNS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ASNN" sboTerm="SBO:0000176" id="R_ASNN" name="ASRGL1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -6137,8 +6137,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__16448"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20123"/> + <fbc:geneProductRef fbc:geneProduct="G_ASRGL1"/> + <fbc:geneProductRef fbc:geneProduct="G_ASPG"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -6169,7 +6169,7 @@ <speciesReference species="M_thf_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7468"/> + <fbc:geneProductRef fbc:geneProduct="G_MTR"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_METAT" sboTerm="SBO:0000176" id="R_METAT" name="MAT" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -6201,10 +6201,10 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6903"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6905"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6904"/> + <fbc:geneProductRef fbc:geneProduct="G_MAT1A"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_MAT2B"/> + <fbc:geneProductRef fbc:geneProduct="G_MAT2A"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -6235,7 +6235,7 @@ <speciesReference species="M_ahcys_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5028"/> + <fbc:geneProductRef fbc:geneProduct="G_HNMT"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_AHCi" sboTerm="SBO:0000176" id="R_AHCi" name="AHCY" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -6265,12 +6265,12 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__642"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7103"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__638"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__634"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__637"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__633"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP8"/> + <fbc:geneProductRef fbc:geneProduct="G_MIP"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP5"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP2"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP4"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -6301,7 +6301,7 @@ <speciesReference species="M_h_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__257"/> + <fbc:geneProductRef fbc:geneProduct="G_ADK"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_CYSTS" sboTerm="SBO:0000176" id="R_CYSTS" name="CBS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -6330,7 +6330,7 @@ <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1550"/> + <fbc:geneProductRef fbc:geneProduct="G_CBS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_CYSTGL" sboTerm="SBO:0000176" id="R_CYSTGL" name="CTH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -6360,7 +6360,7 @@ <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2501"/> + <fbc:geneProductRef fbc:geneProduct="G_CTH"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_MTHFR3" sboTerm="SBO:0000176" id="R_MTHFR3" name="MTHFR" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -6390,7 +6390,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7436"/> + <fbc:geneProductRef fbc:geneProduct="G_MTHFR"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_UNK2" sboTerm="SBO:0000176" id="R_UNK2" name="MetSynthesis" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -6471,8 +6471,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3791"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3795"/> + <fbc:geneProductRef fbc:geneProduct="G_FOLR1"/> + <fbc:geneProductRef fbc:geneProduct="G_FOLR3"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -6502,7 +6502,7 @@ <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__976"/> + <fbc:geneProductRef fbc:geneProduct="G_BCAT1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_3MOPt2im" sboTerm="SBO:0000176" id="R_3MOPt2im" name="Transport3mop" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -6557,7 +6557,7 @@ <speciesReference species="M_glu__L_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__977"/> + <fbc:geneProductRef fbc:geneProduct="G_BCAT2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_LEUTA" sboTerm="SBO:0000176" id="R_LEUTA" name="cBCAT2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -6586,7 +6586,7 @@ <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__976"/> + <fbc:geneProductRef fbc:geneProduct="G_BCAT1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_4MOPt2im" sboTerm="SBO:0000176" id="R_4MOPt2im" name="Transport4mop" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -6641,7 +6641,7 @@ <speciesReference species="M_glu__L_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__977"/> + <fbc:geneProductRef fbc:geneProduct="G_BCAT2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_OIVD1m" sboTerm="SBO:0000176" id="R_OIVD1m" name="BCKD1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -6673,10 +6673,10 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__987"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2898"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2698"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__986"/> + <fbc:geneProductRef fbc:geneProduct="G_BCKDHB"/> + <fbc:geneProductRef fbc:geneProduct="G_DLD"/> + <fbc:geneProductRef fbc:geneProduct="G_DBT"/> + <fbc:geneProductRef fbc:geneProduct="G_BCKDHA"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -6706,7 +6706,7 @@ <speciesReference species="M_fadh2_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6186"/> + <fbc:geneProductRef fbc:geneProduct="G_IVD"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_MCCCrm" sboTerm="SBO:0000176" id="R_MCCCrm" name="MCC" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -6739,8 +6739,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6936"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6937"/> + <fbc:geneProductRef fbc:geneProduct="G_MCCC1"/> + <fbc:geneProductRef fbc:geneProduct="G_MCCC2"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -6769,7 +6769,7 @@ <speciesReference species="M_hmgcoa_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__890"/> + <fbc:geneProductRef fbc:geneProduct="G_AUH"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_HMGCOAtm" sboTerm="SBO:0000176" id="R_HMGCOAtm" name="TransportHMGCoA" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -6822,7 +6822,7 @@ <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__976"/> + <fbc:geneProductRef fbc:geneProduct="G_BCAT1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_3MOBt2im" sboTerm="SBO:0000176" id="R_3MOBt2im" name="Transport3mob" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -6877,7 +6877,7 @@ <speciesReference species="M_glu__L_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__977"/> + <fbc:geneProductRef fbc:geneProduct="G_BCAT2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_OIVD2m" sboTerm="SBO:0000176" id="R_OIVD2m" name="BCKD2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -6909,10 +6909,10 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__987"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2898"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2698"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__986"/> + <fbc:geneProductRef fbc:geneProduct="G_BCKDHB"/> + <fbc:geneProductRef fbc:geneProduct="G_DLD"/> + <fbc:geneProductRef fbc:geneProduct="G_DBT"/> + <fbc:geneProductRef fbc:geneProduct="G_BCKDHA"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -6943,8 +6943,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__89"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__87"/> + <fbc:geneProductRef fbc:geneProduct="G_ACADM"/> + <fbc:geneProductRef fbc:geneProduct="G_ACAD8"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -6974,10 +6974,10 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3151"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4801"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4803"/> + <fbc:geneProductRef fbc:geneProduct="G_ECHS1"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_HADHA"/> + <fbc:geneProductRef fbc:geneProduct="G_HADHB"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -7036,7 +7036,7 @@ <speciesReference species="M_nadh_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4907"/> + <fbc:geneProductRef fbc:geneProduct="G_HIBADH"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0643" sboTerm="SBO:0000176" id="R_r0643" name="HIBADH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -7068,11 +7068,11 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__403"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__404"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__407"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__412"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__877"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDH3A2"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDH2"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDH1B1"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDH9A1"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDH7A1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -7104,7 +7104,7 @@ <speciesReference species="M_ppcoa_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7179"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDH6A1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_MMTSADm" sboTerm="SBO:0000176" id="R_MMTSADm" name="MMAL2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -7214,7 +7214,7 @@ <speciesReference species="M_mmcoa__R_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__16732"/> + <fbc:geneProductRef fbc:geneProduct="G_MCEE"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_MMMm" sboTerm="SBO:0000176" id="R_MMMm" name="MCM2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -7241,7 +7241,7 @@ <speciesReference species="M_succoa_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7526"/> + <fbc:geneProductRef fbc:geneProduct="G_MMUT"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ILEtmi" sboTerm="SBO:0000176" id="R_ILEtmi" name="TransportIle" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -7343,7 +7343,7 @@ <speciesReference species="M_nadh_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8923"/> + <fbc:geneProductRef fbc:geneProduct="G_PHGDH"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PSERT" sboTerm="SBO:0000176" id="R_PSERT" name="PSAT1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -7372,7 +7372,7 @@ <speciesReference species="M_pser__L_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19129"/> + <fbc:geneProductRef fbc:geneProduct="G_PSAT1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PSP_L" sboTerm="SBO:0000176" id="R_PSP_L" name="PSPH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -7401,7 +7401,7 @@ <speciesReference species="M_ser__L_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9577"/> + <fbc:geneProductRef fbc:geneProduct="G_PSPH"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_GHMT2r" sboTerm="SBO:0000176" id="R_GHMT2r" name="cSHMT" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -7431,7 +7431,7 @@ <speciesReference species="M_mlthf_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10850"/> + <fbc:geneProductRef fbc:geneProduct="G_SHMT1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_SERD_L" sboTerm="SBO:0000176" id="R_SERD_L" name="SDS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -7460,8 +7460,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10691"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30404"/> + <fbc:geneProductRef fbc:geneProduct="G_SDS"/> + <fbc:geneProductRef fbc:geneProduct="G_SDSL"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -7492,8 +7492,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18062"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4552"/> + <fbc:geneProductRef fbc:geneProduct="G_GPT2"/> + <fbc:geneProductRef fbc:geneProduct="G_GPT"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -7572,7 +7572,7 @@ <speciesReference species="M_mlthf_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10852"/> + <fbc:geneProductRef fbc:geneProduct="G_SHMT2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_MLTHFtm" sboTerm="SBO:0000176" id="R_MLTHFtm" name="mlthf Transport" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -7623,7 +7623,7 @@ <speciesReference species="M_fol_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29683"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A32"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_FORtm" sboTerm="SBO:0000176" id="R_FORtm" name="TransportFormate" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -7676,7 +7676,7 @@ <speciesReference species="M_nadp_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2861"/> + <fbc:geneProductRef fbc:geneProduct="G_DHFR"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_DHFRim" sboTerm="SBO:0000176" id="R_DHFRim" name="DHFRL1_DHFR_6" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -7706,7 +7706,7 @@ <speciesReference species="M_thf_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2861"/> + <fbc:geneProductRef fbc:geneProduct="G_DHFR"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_FTHFLmi" sboTerm="SBO:0000176" id="R_FTHFLmi" name="mMTHFD1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -7738,8 +7738,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7432"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21055"/> + <fbc:geneProductRef fbc:geneProduct="G_MTHFD1"/> + <fbc:geneProductRef fbc:geneProduct="G_MTHFD1L"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -7769,7 +7769,7 @@ <speciesReference species="M_methf_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7434"/> + <fbc:geneProductRef fbc:geneProduct="G_MTHFD2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_MTHFDm" sboTerm="SBO:0000176" id="R_MTHFDm" name="mMTHFD3" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -7799,8 +7799,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7434"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7432"/> + <fbc:geneProductRef fbc:geneProduct="G_MTHFD2"/> + <fbc:geneProductRef fbc:geneProduct="G_MTHFD1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -7830,7 +7830,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2861"/> + <fbc:geneProductRef fbc:geneProduct="G_DHFR"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_DHFR" sboTerm="SBO:0000176" id="R_DHFR" name="cDHFR2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -7860,7 +7860,7 @@ <speciesReference species="M_thf_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2861"/> + <fbc:geneProductRef fbc:geneProduct="G_DHFR"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_FTHFLi" sboTerm="SBO:0000176" id="R_FTHFLi" name="cMTHFD1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -7891,7 +7891,7 @@ <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7432"/> + <fbc:geneProductRef fbc:geneProduct="G_MTHFD1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_FTHFDH" sboTerm="SBO:0000176" id="R_FTHFDH" name="cMTHFD2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -7924,8 +7924,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26777"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3978"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDH1L2"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDH1L1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -7955,7 +7955,7 @@ <speciesReference species="M_methf_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7432"/> + <fbc:geneProductRef fbc:geneProduct="G_MTHFD1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_MTHFD" sboTerm="SBO:0000176" id="R_MTHFD" name="cMTHFD4" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -7985,8 +7985,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7432"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7436"/> + <fbc:geneProductRef fbc:geneProduct="G_MTHFD1"/> + <fbc:geneProductRef fbc:geneProduct="G_MTHFR"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -8017,8 +8017,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7434"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__31865"/> + <fbc:geneProductRef fbc:geneProduct="G_MTHFD2"/> + <fbc:geneProductRef fbc:geneProduct="G_MTHFD2L"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -8047,7 +8047,7 @@ <speciesReference species="M_coa_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__94"/> + <fbc:geneProductRef fbc:geneProduct="G_ACAT2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_HMGCOAS" sboTerm="SBO:0000176" id="R_HMGCOAS" name="cHMGCS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -8078,7 +8078,7 @@ <speciesReference species="M_hmgcoa_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5007"/> + <fbc:geneProductRef fbc:geneProduct="G_HMGCS1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_HMGCOAR" sboTerm="SBO:0000176" id="R_HMGCOAR" name="Hydroxymethylglutaryl CoA reductase" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -8109,7 +8109,7 @@ <speciesReference species="M_nadp_c" stoichiometry="2" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5006"/> + <fbc:geneProductRef fbc:geneProduct="G_HMGCR"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_MEVK1" sboTerm="SBO:0000176" id="R_MEVK1" name="Mevalonate kinase atp" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -8139,7 +8139,7 @@ <speciesReference species="M_h_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7530"/> + <fbc:geneProductRef fbc:geneProduct="G_MVK"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PMEVK" sboTerm="SBO:0000176" id="R_PMEVK" name="Phosphomevalonate kinase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -8168,7 +8168,7 @@ <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9141"/> + <fbc:geneProductRef fbc:geneProduct="G_PMVK"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_IPDDI" sboTerm="SBO:0000176" id="R_IPDDI" name="Isopentenyl-diphosphate D-isomerase" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -8196,8 +8196,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5387"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23487"/> + <fbc:geneProductRef fbc:geneProduct="G_IDI1"/> + <fbc:geneProductRef fbc:geneProduct="G_IDI2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -8229,7 +8229,7 @@ <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7529"/> + <fbc:geneProductRef fbc:geneProduct="G_MVD"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_DMATT" sboTerm="SBO:0000176" id="R_DMATT" name="Dimethylallyltranstransferase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -8258,7 +8258,7 @@ <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4249"/> + <fbc:geneProductRef fbc:geneProduct="G_GGPS1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_GRTT" sboTerm="SBO:0000176" id="R_GRTT" name="Geranyltranstransferase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -8287,7 +8287,7 @@ <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4249"/> + <fbc:geneProductRef fbc:geneProduct="G_GGPS1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_HMR_1465" sboTerm="SBO:0000176" id="R_HMR_1465" name="Farnesyl-Diphosphate:Farnesyl-Diphosphate Farnesyltransferase" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -8315,7 +8315,7 @@ <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3629"/> + <fbc:geneProductRef fbc:geneProduct="G_FDFT1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_HMR_1467" sboTerm="SBO:0000176" id="R_HMR_1467" name="Presqualene-Diphosphate Diphosphate-Lyase (Reducing, Squalene-Forming)" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -8346,7 +8346,7 @@ <speciesReference species="M_sql_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3629"/> + <fbc:geneProductRef fbc:geneProduct="G_FDFT1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_SMO" sboTerm="SBO:0000176" id="R_SMO" name="Squalene monooxygenase" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -8378,7 +8378,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11279"/> + <fbc:geneProductRef fbc:geneProduct="G_SQLE"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_LNSTLS" sboTerm="SBO:0000176" id="R_LNSTLS" name="Lanosterol synthase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -8405,7 +8405,7 @@ <speciesReference species="M_lanost_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6708"/> + <fbc:geneProductRef fbc:geneProduct="G_LSS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_HMR_1477" sboTerm="SBO:0000176" id="R_HMR_1477" name="Sterol 14Alpha-Demethylase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -8437,7 +8437,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2649"/> + <fbc:geneProductRef fbc:geneProduct="G_CYP51A1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_HMR_1478" sboTerm="SBO:0000176" id="R_HMR_1478" name="Sterol 14Alpha-Demethylase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -8469,7 +8469,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2649"/> + <fbc:geneProductRef fbc:geneProduct="G_CYP51A1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_HMR_1479" sboTerm="SBO:0000176" id="R_HMR_1479" name="Sterol 14Alpha-Demethylase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -8501,7 +8501,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2649"/> + <fbc:geneProductRef fbc:geneProduct="G_CYP51A1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_C14STR" sboTerm="SBO:0000176" id="R_C14STR" name="C 14 sterol reductase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -8532,8 +8532,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6518"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11863"/> + <fbc:geneProductRef fbc:geneProduct="G_LBR"/> + <fbc:geneProductRef fbc:geneProduct="G_TM7SF2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -8567,8 +8567,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10545"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1334"/> + <fbc:geneProductRef fbc:geneProduct="G_MSMO1"/> + <fbc:geneProductRef fbc:geneProduct="G_FAXDC2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -8602,8 +8602,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10545"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1334"/> + <fbc:geneProductRef fbc:geneProduct="G_MSMO1"/> + <fbc:geneProductRef fbc:geneProduct="G_FAXDC2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -8637,8 +8637,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10545"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1334"/> + <fbc:geneProductRef fbc:geneProduct="G_MSMO1"/> + <fbc:geneProductRef fbc:geneProduct="G_FAXDC2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -8670,7 +8670,7 @@ <speciesReference species="M_nadh_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13398"/> + <fbc:geneProductRef fbc:geneProduct="G_NSDHL"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_HMR_1495" sboTerm="SBO:0000176" id="R_HMR_1495" name="3Beta-Hydroxysteroid-4Alpha-Carboxylate 3-Dehydrogenase (Decarboxylating)" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -8702,8 +8702,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13398"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19340"/> + <fbc:geneProductRef fbc:geneProduct="G_NSDHL"/> + <fbc:geneProductRef fbc:geneProduct="G_MAGEA2B"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -8734,7 +8734,7 @@ <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5215"/> + <fbc:geneProductRef fbc:geneProduct="G_HSD17B7"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_HMR_1502" sboTerm="SBO:0000176" id="R_HMR_1502" name="Methylsterol Monooxygenase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -8767,8 +8767,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10545"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1334"/> + <fbc:geneProductRef fbc:geneProduct="G_MSMO1"/> + <fbc:geneProductRef fbc:geneProduct="G_FAXDC2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -8802,8 +8802,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10545"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1334"/> + <fbc:geneProductRef fbc:geneProduct="G_MSMO1"/> + <fbc:geneProductRef fbc:geneProduct="G_FAXDC2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -8837,8 +8837,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10545"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1334"/> + <fbc:geneProductRef fbc:geneProduct="G_MSMO1"/> + <fbc:geneProductRef fbc:geneProduct="G_FAXDC2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -8870,7 +8870,7 @@ <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13398"/> + <fbc:geneProductRef fbc:geneProduct="G_NSDHL"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_HMR_1509" sboTerm="SBO:0000176" id="R_HMR_1509" name="3Beta-Hydroxysteroid 3-Dehydrogenase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -8900,7 +8900,7 @@ <speciesReference species="M_zymst_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5215"/> + <fbc:geneProductRef fbc:geneProduct="G_HSD17B7"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_CHLSTI_1" sboTerm="SBO:0000176" id="R_CHLSTI_1" name="Delta8,24-cholestadien-3beta-ol delta7-delta8-isomerase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -8927,7 +8927,7 @@ <speciesReference species="M_chlstol_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3133"/> + <fbc:geneProductRef fbc:geneProduct="G_EBP"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_HMR_1516" sboTerm="SBO:0000176" id="R_HMR_1516" name="HMR 1516" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -8959,7 +8959,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10547"/> + <fbc:geneProductRef fbc:geneProduct="G_SC5D"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_RE2410C" sboTerm="SBO:0000176" id="R_RE2410C" name="7-Dehydrocholesterol Reductase" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -9016,7 +9016,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2859"/> + <fbc:geneProductRef fbc:geneProduct="G_DHCR24"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ACCOAC" sboTerm="SBO:0000176" id="R_ACCOAC" name="ACC" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9049,8 +9049,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__85"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__84"/> + <fbc:geneProductRef fbc:geneProduct="G_ACACB"/> + <fbc:geneProductRef fbc:geneProduct="G_ACACA"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -9080,7 +9080,7 @@ <speciesReference species="M_coa_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_MCAT" sboTerm="SBO:0000176" id="R_MCAT" name="MCAT" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9109,7 +9109,7 @@ <speciesReference species="M_malACP_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_AcetoacetylACPsynthesis" sboTerm="SBO:0000176" id="R_AcetoacetylACPsynthesis" name="AcetoacetylACPsynthesis" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9139,7 +9139,7 @@ <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0691" sboTerm="SBO:0000176" id="R_r0691" name="r0691" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9169,7 +9169,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0681" sboTerm="SBO:0000176" id="R_r0681" name="r0681" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9197,7 +9197,7 @@ <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0682" sboTerm="SBO:0000176" id="R_r0682" name="r0682" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9227,7 +9227,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0760" sboTerm="SBO:0000176" id="R_r0760" name="r0760" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9257,7 +9257,7 @@ <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0761" sboTerm="SBO:0000176" id="R_r0761" name="r0761" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9287,7 +9287,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0762" sboTerm="SBO:0000176" id="R_r0762" name="r0762" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -9315,7 +9315,7 @@ <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0763" sboTerm="SBO:0000176" id="R_r0763" name="r0763" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9345,7 +9345,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0764" sboTerm="SBO:0000176" id="R_r0764" name="r0764" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9375,7 +9375,7 @@ <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0694" sboTerm="SBO:0000176" id="R_r0694" name="r0694" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9405,7 +9405,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0695" sboTerm="SBO:0000176" id="R_r0695" name="r0695" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9433,7 +9433,7 @@ <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0765" sboTerm="SBO:0000176" id="R_r0765" name="r0765" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9463,7 +9463,7 @@ <speciesReference species="M_octanoyl_ACP_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0766" sboTerm="SBO:0000176" id="R_r0766" name="r0766" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9493,7 +9493,7 @@ <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0692" sboTerm="SBO:0000176" id="R_r0692" name="r0692" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9523,7 +9523,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0693" sboTerm="SBO:0000176" id="R_r0693" name="r0693" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9551,7 +9551,7 @@ <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0767" sboTerm="SBO:0000176" id="R_r0767" name="r0767" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9581,7 +9581,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0768" sboTerm="SBO:0000176" id="R_r0768" name="r0768" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9611,7 +9611,7 @@ <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0769" sboTerm="SBO:0000176" id="R_r0769" name="r0769" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9641,7 +9641,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0770" sboTerm="SBO:0000176" id="R_r0770" name="r0770" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9669,7 +9669,7 @@ <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0712" sboTerm="SBO:0000176" id="R_r0712" name="r0712" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9699,7 +9699,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0713" sboTerm="SBO:0000176" id="R_r0713" name="r0713" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9729,7 +9729,7 @@ <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0701" sboTerm="SBO:0000176" id="R_r0701" name="r0701" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9759,7 +9759,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0702" sboTerm="SBO:0000176" id="R_r0702" name="r0702" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9787,7 +9787,7 @@ <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0771" sboTerm="SBO:0000176" id="R_r0771" name="r0771" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9817,7 +9817,7 @@ <speciesReference species="M_tetradecanoyl_ACP_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0772" sboTerm="SBO:0000176" id="R_r0772" name="r0772" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9847,7 +9847,7 @@ <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0696" sboTerm="SBO:0000176" id="R_r0696" name="r0696" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9877,7 +9877,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0697" sboTerm="SBO:0000176" id="R_r0697" name="r0697" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9905,7 +9905,7 @@ <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0773" sboTerm="SBO:0000176" id="R_r0773" name="r0773" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -9935,7 +9935,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_FA160ACPH" sboTerm="SBO:0000176" id="R_FA160ACPH" name="FA160ACPH" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -9965,8 +9965,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__25625"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3594"/> + <fbc:geneProductRef fbc:geneProduct="G_OLAH"/> + <fbc:geneProductRef fbc:geneProduct="G_FASN"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -9999,10 +9999,10 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3571"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3570"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3569"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__16496"/> + <fbc:geneProductRef fbc:geneProduct="G_ACSL4"/> + <fbc:geneProductRef fbc:geneProduct="G_ACSL3"/> + <fbc:geneProductRef fbc:geneProduct="G_ACSL1"/> + <fbc:geneProductRef fbc:geneProduct="G_ACSL6"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -10033,9 +10033,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2328"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18540"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2329"/> + <fbc:geneProductRef fbc:geneProduct="G_CPT1A"/> + <fbc:geneProductRef fbc:geneProduct="G_CPT1C"/> + <fbc:geneProductRef fbc:geneProduct="G_CPT1B"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -10065,7 +10065,7 @@ <speciesReference species="M_pmtcrn_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1421"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A20"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_carnitineAcylTransferaseII" sboTerm="SBO:0000176" id="R_carnitineAcylTransferaseII" name="carnitineAcylTransferaseII" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -10094,7 +10094,7 @@ <speciesReference species="M_ptth_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2330"/> + <fbc:geneProductRef fbc:geneProduct="G_CPT2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_betaOxidation" sboTerm="SBO:0000176" id="R_betaOxidation" name="betaOxidation" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -10129,15 +10129,15 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__92"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4801"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3482"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__88"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__89"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3151"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4803"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3481"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__83"/> + <fbc:geneProductRef fbc:geneProduct="G_ACADVL"/> + <fbc:geneProductRef fbc:geneProduct="G_HADHA"/> + <fbc:geneProductRef fbc:geneProduct="G_ETFB"/> + <fbc:geneProductRef fbc:geneProduct="G_ACADL"/> + <fbc:geneProductRef fbc:geneProduct="G_ACADM"/> + <fbc:geneProductRef fbc:geneProduct="G_ECHS1"/> + <fbc:geneProductRef fbc:geneProduct="G_HADHB"/> + <fbc:geneProductRef fbc:geneProduct="G_ETFA"/> + <fbc:geneProductRef fbc:geneProduct="G_ACAA2"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -10224,32 +10224,32 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11007"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11036"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11039"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11040"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13446"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14025"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11005"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__22146"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14239"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13812"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11041"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11037"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11010"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18067"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__28750"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__15956"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23155"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23091"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11011"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11006"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18301"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11009"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13445"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13444"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11038"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19119"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A3"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC5A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC5A4"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC5A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A9"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC5A7"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC5A9"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A11"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A8"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC5A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC5A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A12"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC5A12"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A13"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC5A10"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC5A11"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A14"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A4"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A7"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A10"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC5A3"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC5A8"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -10304,29 +10304,29 @@ <fbc:geneProductAssociation> <fbc:or> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11058"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11026"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18070"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18044"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A10"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC3A2"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A3"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC43A1"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A18"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A4"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -10356,9 +10356,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3791"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3795"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3793"/> + <fbc:geneProductRef fbc:geneProduct="G_FOLR1"/> + <fbc:geneProductRef fbc:geneProduct="G_FOLR3"/> + <fbc:geneProductRef fbc:geneProduct="G_FOLR2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -10412,22 +10412,22 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11067"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11057"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11060"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11061"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11026"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11065"/> - </fbc:and> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11026"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A9"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A18"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A3"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC3A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A7"/> + </fbc:and> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC3A2"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -10458,29 +10458,29 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11061"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11060"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11057"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A3"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A4"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> </fbc:or> </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17027"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23087"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11066"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC16A10"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC43A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC43A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A8"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A18"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -10511,22 +10511,22 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23087"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC43A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC43A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A18"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -10557,28 +10557,28 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11061"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11026"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11060"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11057"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23087"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A3"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC3A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A4"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC43A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC43A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A18"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -10609,22 +10609,22 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23087"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC43A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC43A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A18"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -10655,25 +10655,25 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10969"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23087"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC22A5"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC43A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC43A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A18"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -10704,26 +10704,26 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18070"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18761"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A4"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC36A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC43A1"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A18"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -10755,33 +10755,33 @@ <fbc:geneProductAssociation> <fbc:or> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11058"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11026"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11056"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11056"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11051"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18070"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18762"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18761"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A10"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC3A2"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A4"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A9"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A9"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A5"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A18"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC36A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC36A1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -10811,26 +10811,26 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18070"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18044"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A4"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A3"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC43A1"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A18"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -10861,27 +10861,27 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11054"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30927"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19660"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18762"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18761"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A4"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A2"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A7"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A20"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC36A4"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC36A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC36A1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -10910,10 +10910,10 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4433"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10995"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1663"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10998"/> + <fbc:geneProductRef fbc:geneProduct="G_GOT2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC27A1"/> + <fbc:geneProductRef fbc:geneProduct="G_CD36"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC27A4"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -10966,11 +10966,11 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__16270"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10928"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10924"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10922"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19119"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC16A8"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC16A7"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC16A3"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC16A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC5A8"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -10999,8 +10999,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10919"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10918"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC14A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC14A1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -11125,8 +11125,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11003"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11004"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC29A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC29A2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -11179,12 +11179,12 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__642"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7103"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__638"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__634"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__637"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__633"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP8"/> + <fbc:geneProductRef fbc:geneProduct="G_MIP"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP5"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP2"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP4"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -11286,16 +11286,16 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10944"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10939"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10941"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10940"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10945"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18044"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10971"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC1A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC1A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC1A3"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC1A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC1A7"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A3"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC22A7"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A18"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -11326,33 +11326,33 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11060"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11057"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11061"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18070"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18044"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10942"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19660"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18762"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18761"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A4"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A3"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A3"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC1A4"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A18"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC36A4"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC36A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC36A1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -11382,12 +11382,12 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10944"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10939"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10941"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10940"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10945"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18044"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC1A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC1A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC1A3"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC1A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC1A7"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A3"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -11445,7 +11445,7 @@ <speciesReference species="M_h_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4136"/> + <fbc:geneProductRef fbc:geneProduct="G_GAMT"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_CKc_cho" sboTerm="SBO:0000176" id="R_CKc_cho" name="CK" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -11476,8 +11476,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1994"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1991"/> + <fbc:geneProductRef fbc:geneProduct="G_CKM"/> + <fbc:geneProductRef fbc:geneProduct="G_CKB"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -11557,12 +11557,12 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7851"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20461"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20567"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7849"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7850"/> + <fbc:geneProductRef fbc:geneProduct="G_NME3"/> + <fbc:geneProductRef fbc:geneProduct="G_NME7"/> + <fbc:geneProductRef fbc:geneProduct="G_NME6"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_NME1"/> + <fbc:geneProductRef fbc:geneProduct="G_NME2"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -11594,12 +11594,12 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7851"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20461"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20567"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7849"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7850"/> + <fbc:geneProductRef fbc:geneProduct="G_NME3"/> + <fbc:geneProductRef fbc:geneProduct="G_NME7"/> + <fbc:geneProductRef fbc:geneProduct="G_NME6"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_NME1"/> + <fbc:geneProductRef fbc:geneProduct="G_NME2"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -11631,12 +11631,12 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7851"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20461"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20567"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7849"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7850"/> + <fbc:geneProductRef fbc:geneProduct="G_NME3"/> + <fbc:geneProductRef fbc:geneProduct="G_NME7"/> + <fbc:geneProductRef fbc:geneProduct="G_NME6"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_NME1"/> + <fbc:geneProductRef fbc:geneProduct="G_NME2"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -11668,12 +11668,12 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7851"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20461"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20567"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7849"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7850"/> + <fbc:geneProductRef fbc:geneProduct="G_NME3"/> + <fbc:geneProductRef fbc:geneProduct="G_NME7"/> + <fbc:geneProductRef fbc:geneProduct="G_NME6"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_NME1"/> + <fbc:geneProductRef fbc:geneProduct="G_NME2"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -11704,7 +11704,7 @@ <speciesReference species="M_dtdp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3061"/> + <fbc:geneProductRef fbc:geneProduct="G_DTYMK"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_NDPK4" sboTerm="SBO:0000176" id="R_NDPK4" name="dTTPsynth" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -11734,12 +11734,12 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7851"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20461"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20567"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7849"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7850"/> + <fbc:geneProductRef fbc:geneProduct="G_NME3"/> + <fbc:geneProductRef fbc:geneProduct="G_NME7"/> + <fbc:geneProductRef fbc:geneProduct="G_NME6"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_NME1"/> + <fbc:geneProductRef fbc:geneProduct="G_NME2"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -11770,15 +11770,15 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18044"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11067"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18070"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11056"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A4"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A3"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A9"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A9"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -11811,9 +11811,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__80"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__550"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__549"/> + <fbc:geneProductRef fbc:geneProduct="G_AOC1"/> + <fbc:geneProductRef fbc:geneProduct="G_AOC3"/> + <fbc:geneProductRef fbc:geneProduct="G_AOC2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -11845,7 +11845,7 @@ <speciesReference species="M_nadh_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__412"/> + <fbc:geneProductRef fbc:geneProduct="G_ALDH9A1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0465_1" sboTerm="SBO:0000176" id="R_r0465_1" name="HisAbutLigase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -11877,7 +11877,7 @@ <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29268"/> + <fbc:geneProductRef fbc:geneProduct="G_CARNS1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ABUTH" sboTerm="SBO:0000176" id="R_ABUTH" name="ABUTH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -11907,12 +11907,12 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__642"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7103"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__638"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__634"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__637"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__633"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP8"/> + <fbc:geneProductRef fbc:geneProduct="G_MIP"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP5"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP2"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP4"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -11943,8 +11943,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4093"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4092"/> + <fbc:geneProductRef fbc:geneProduct="G_GAD2"/> + <fbc:geneProductRef fbc:geneProduct="G_GAD1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -11973,7 +11973,7 @@ <speciesReference species="M_urcan_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4806"/> + <fbc:geneProductRef fbc:geneProduct="G_HAL"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_URCN" sboTerm="SBO:0000176" id="R_URCN" name="URCN" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -12002,12 +12002,12 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__642"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7103"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__638"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__634"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__637"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__633"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP8"/> + <fbc:geneProductRef fbc:geneProduct="G_MIP"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP5"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP2"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP4"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -12037,7 +12037,7 @@ <speciesReference species="M_h_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__28577"/> + <fbc:geneProductRef fbc:geneProduct="G_AMDHD1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_GluForTx" sboTerm="SBO:0000176" id="R_GluForTx" name="GluForTx" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -12067,7 +12067,7 @@ <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3974"/> + <fbc:geneProductRef fbc:geneProduct="G_FTCD"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_FTCD" sboTerm="SBO:0000176" id="R_FTCD" name="FTCD" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -12096,7 +12096,7 @@ <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3974"/> + <fbc:geneProductRef fbc:geneProduct="G_FTCD"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_NBAHH_ir" sboTerm="SBO:0000176" id="R_NBAHH_ir" name="NBAHH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -12126,12 +12126,12 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__642"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7103"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__638"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__634"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__637"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__633"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP8"/> + <fbc:geneProductRef fbc:geneProduct="G_MIP"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP5"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP2"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP4"/> + <fbc:geneProductRef fbc:geneProduct="G_AQP1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -12164,7 +12164,7 @@ <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29268"/> + <fbc:geneProductRef fbc:geneProduct="G_CARNS1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ASP1DC" sboTerm="SBO:0000176" id="R_ASP1DC" name="ASP1DC" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -12193,7 +12193,7 @@ <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4092"/> + <fbc:geneProductRef fbc:geneProduct="G_GAD1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_lys_L_t" sboTerm="SBO:0000176" id="R_lys_L_t" name="ExLys" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound"> @@ -12222,14 +12222,14 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10969"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11057"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11060"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11061"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11067"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC22A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A4"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A3"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A9"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -12260,8 +12260,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10985"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__22921"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A15"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -12294,7 +12294,7 @@ <speciesReference species="M_saccrp__L_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17366"/> + <fbc:geneProductRef fbc:geneProduct="G_AASS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_r0525" sboTerm="SBO:0000176" id="R_r0525" name="SACCRPOX" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -12326,7 +12326,7 @@ <speciesReference species="M_nadh_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17366"/> + <fbc:geneProductRef fbc:geneProduct="G_AASS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_AASAD3m" sboTerm="SBO:0000176" id="R_AASAD3m" name="AASAD3m" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -12383,7 +12383,7 @@ <speciesReference species="M_glu__L_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17929"/> + <fbc:geneProductRef fbc:geneProduct="G_AADAT"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_2OXOADOXm" sboTerm="SBO:0000176" id="R_2OXOADOXm" name="OXOADPOR" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -12415,10 +12415,10 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2898"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8124"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21350"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2911"/> + <fbc:geneProductRef fbc:geneProduct="G_DLD"/> + <fbc:geneProductRef fbc:geneProduct="G_OGDH"/> + <fbc:geneProductRef fbc:geneProduct="G_PDHX"/> + <fbc:geneProductRef fbc:geneProduct="G_DLST"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -12450,7 +12450,7 @@ <speciesReference species="M_fadh2_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4189"/> + <fbc:geneProductRef fbc:geneProduct="G_GCDH"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_3HBCDm" sboTerm="SBO:0000176" id="R_3HBCDm" name="ECOAH1m" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -12478,7 +12478,7 @@ <speciesReference species="M_3hbcoa__R_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23408"/> + <fbc:geneProductRef fbc:geneProduct="G_ECHDC2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_HACD1m" sboTerm="SBO:0000176" id="R_HACD1m" name="HACD1m" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -12509,11 +12509,11 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4799"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4800"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4801"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4803"/> + <fbc:geneProductRef fbc:geneProduct="G_HADH"/> + <fbc:geneProductRef fbc:geneProduct="G_HSD17B10"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_HADHA"/> + <fbc:geneProductRef fbc:geneProduct="G_HADHB"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -12546,7 +12546,7 @@ <speciesReference species="M_hmgcoa_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5008"/> + <fbc:geneProductRef fbc:geneProduct="G_HMGCS2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_cys_L_t" sboTerm="SBO:0000176" id="R_cys_L_t" name="ExCys" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -12575,23 +12575,23 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23087"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18070"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A2"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC43A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A5"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A18"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -12622,7 +12622,7 @@ <speciesReference species="M_h_c" stoichiometry="2" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1795"/> + <fbc:geneProductRef fbc:geneProduct="G_CDO1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_3SALATAi" sboTerm="SBO:0000176" id="R_3SALATAi" name="3SALATAc" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -12652,7 +12652,7 @@ <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4432"/> + <fbc:geneProductRef fbc:geneProduct="G_GOT1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_3SALAASPm" sboTerm="SBO:0000176" id="R_3SALAASPm" name="Transport3SALA" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -12682,8 +12682,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10983"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10982"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A13"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A12"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -12714,7 +12714,7 @@ <speciesReference species="M_glu__L_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4433"/> + <fbc:geneProductRef fbc:geneProduct="G_GOT2"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_3SPYRSP" sboTerm="SBO:0000176" id="R_3SPYRSP" name="3SPYRSTc" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -12847,7 +12847,7 @@ <speciesReference species="M_tyr__L_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8582"/> + <fbc:geneProductRef fbc:geneProduct="G_PAH"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_tyr_L_t" sboTerm="SBO:0000176" id="R_tyr_L_t" name="ExTyr" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -12876,21 +12876,21 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17027"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC16A10"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A18"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -12922,8 +12922,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4432"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11573"/> + <fbc:geneProductRef fbc:geneProduct="G_GOT1"/> + <fbc:geneProductRef fbc:geneProduct="G_TAT"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -12953,7 +12953,7 @@ <speciesReference species="M_hgentis_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5147"/> + <fbc:geneProductRef fbc:geneProduct="G_HPD"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_HGNTOR" sboTerm="SBO:0000176" id="R_HGNTOR" name="HGNTOR" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -12982,7 +12982,7 @@ <speciesReference species="M_h_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4892"/> + <fbc:geneProductRef fbc:geneProduct="G_HGD"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_MACACI" sboTerm="SBO:0000176" id="R_MACACI" name="MACACI" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -13009,7 +13009,7 @@ <speciesReference species="M_4fumacac_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4643"/> + <fbc:geneProductRef fbc:geneProduct="G_GSTZ1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_FUMAC" sboTerm="SBO:0000176" id="R_FUMAC" name="FUMAC" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -13039,7 +13039,7 @@ <speciesReference species="M_h_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3579"/> + <fbc:geneProductRef fbc:geneProduct="G_FAH"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_AACOAT" sboTerm="SBO:0000176" id="R_AACOAT" name="AACOAT" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -13070,7 +13070,7 @@ <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21298"/> + <fbc:geneProductRef fbc:geneProduct="G_AACS"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_thr_L_t" sboTerm="SBO:0000176" id="R_thr_L_t" name="ExThr" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound"> @@ -13099,20 +13099,20 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC38A2"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC43A1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -13142,8 +13142,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10691"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30404"/> + <fbc:geneProductRef fbc:geneProduct="G_SDS"/> + <fbc:geneProductRef fbc:geneProduct="G_SDSL"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -13225,23 +13225,23 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/> - </fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19660"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17027"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A19"/> + <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC6A18"/> + <fbc:geneProductRef fbc:geneProduct="G_CLTRN"/> + </fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_SLC36A4"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC16A10"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -13271,9 +13271,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6059"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27269"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11708"/> + <fbc:geneProductRef fbc:geneProduct="G_IDO1"/> + <fbc:geneProductRef fbc:geneProduct="G_IDO2"/> + <fbc:geneProductRef fbc:geneProduct="G_TDO2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -13304,7 +13304,7 @@ <speciesReference species="M_h_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20910"/> + <fbc:geneProductRef fbc:geneProduct="G_AFMID"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_KYN" sboTerm="SBO:0000176" id="R_KYN" name="KYN" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -13334,7 +13334,7 @@ <speciesReference species="M_h_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6469"/> + <fbc:geneProductRef fbc:geneProduct="G_KYNU"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ANTHte" sboTerm="SBO:0000176" id="R_ANTHte" name="ExAnth" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -13390,7 +13390,7 @@ <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6381"/> + <fbc:geneProductRef fbc:geneProduct="G_KMO"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_HKYNH" sboTerm="SBO:0000176" id="R_HKYNH" name="HKYNH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -13419,7 +13419,7 @@ <speciesReference species="M_ala__L_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6469"/> + <fbc:geneProductRef fbc:geneProduct="G_KYNU"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_3HAO" sboTerm="SBO:0000176" id="R_3HAO" name="3HAO" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -13448,7 +13448,7 @@ <speciesReference species="M_h_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4796"/> + <fbc:geneProductRef fbc:geneProduct="G_HAAO"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PCLAD" sboTerm="SBO:0000176" id="R_PCLAD" name="PCLAD" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -13477,7 +13477,7 @@ <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19288"/> + <fbc:geneProductRef fbc:geneProduct="G_ACMSD"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_AM6SAD" sboTerm="SBO:0000176" id="R_AM6SAD" name="AM6SADH" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -13563,7 +13563,7 @@ <speciesReference species="M_akg_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14411"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A21"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_CystinePyruvate" sboTerm="SBO:0000176" id="R_CystinePyruvate" name="CystinePyruvate" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -13620,8 +13620,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18155"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12437"/> + <fbc:geneProductRef fbc:geneProduct="G_TXNRD2"/> + <fbc:geneProductRef fbc:geneProduct="G_TXNRD1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -13704,10 +13704,10 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__93"/> - <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4801"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4803"/> + <fbc:geneProductRef fbc:geneProduct="G_ACAT1"/> + <fbc:and> + <fbc:geneProductRef fbc:geneProduct="G_HADHA"/> + <fbc:geneProductRef fbc:geneProduct="G_HADHB"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -13739,7 +13739,7 @@ <speciesReference species="M_nad_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4455"/> + <fbc:geneProductRef fbc:geneProduct="G_GPD1"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_GLYC3Ptm" sboTerm="SBO:0000176" id="R_GLYC3Ptm" name="Transport_glycerol3P" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -13889,8 +13889,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11831"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11830"/> + <fbc:geneProductRef fbc:geneProduct="G_TK2"/> + <fbc:geneProductRef fbc:geneProduct="G_TK1"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -13919,8 +13919,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11003"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11004"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC29A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC29A2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -14065,9 +14065,9 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__16703"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20151"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__16704"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC17A6"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC17A8"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC17A7"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -14162,11 +14162,11 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13812"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11005"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11007"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11006"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13444"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A8"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A3"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A2"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC2A10"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -14197,8 +14197,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4118"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4119"/> + <fbc:geneProductRef fbc:geneProduct="G_GALK1"/> + <fbc:geneProductRef fbc:geneProduct="G_GALK2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -14228,7 +14228,7 @@ <speciesReference species="M_udpgal_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4135"/> + <fbc:geneProductRef fbc:geneProduct="G_GALT"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_PGMT" id="R_PGMT" name="Phosphoglucomutase" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -14256,8 +14256,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8905"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8906"/> + <fbc:geneProductRef fbc:geneProduct="G_PGM1"/> + <fbc:geneProductRef fbc:geneProduct="G_PGM2"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -14285,7 +14285,7 @@ <speciesReference species="M_udpgal_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4116"/> + <fbc:geneProductRef fbc:geneProduct="G_GALE"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_t_Lcystin_ala__L" id="R_t_Lcystin_ala__L" name="t_Lcystin_ala__L" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -14315,8 +14315,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11067"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11025"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A9"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC3A1"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -14347,8 +14347,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11059"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11026"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A11"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC3A2"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -14379,8 +14379,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11067"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11025"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A9"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC3A1"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -14411,8 +14411,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11025"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11067"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC3A1"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC7A9"/> </fbc:and> </fbc:geneProductAssociation> </reaction> @@ -14442,7 +14442,7 @@ <speciesReference species="M_coa_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2342"/> + <fbc:geneProductRef fbc:geneProduct="G_CRAT"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_CRNCARtm" id="R_CRNCARtm" name="Fatty acid oxidation" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -14471,7 +14471,7 @@ <speciesReference species="M_crn_c" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1421"/> + <fbc:geneProductRef fbc:geneProduct="G_SLC25A20"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_CSNATm" id="R_CSNATm" name="Citrate Lyase" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub"> @@ -14500,7 +14500,7 @@ <speciesReference species="M_crn_m" stoichiometry="1" constant="true"/> </listOfProducts> <fbc:geneProductAssociation> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2342"/> + <fbc:geneProductRef fbc:geneProduct="G_CRAT"/> </fbc:geneProductAssociation> </reaction> <reaction metaid="meta_R_ACS" sboTerm="SBO:0000176" id="R_ACS" name="Acetyl-CoA synthetase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub"> @@ -14586,8 +14586,8 @@ </listOfProducts> <fbc:geneProductAssociation> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__15814"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21298"/> + <fbc:geneProductRef fbc:geneProduct="G_ACSS2"/> + <fbc:geneProductRef fbc:geneProduct="G_AACS"/> </fbc:or> </fbc:geneProductAssociation> </reaction> @@ -14673,19 +14673,19 @@ <fbc:geneProductAssociation> <fbc:or> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2898"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21350"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2896"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8808"/> + <fbc:geneProductRef fbc:geneProduct="G_DLD"/> + <fbc:geneProductRef fbc:geneProduct="G_PDHX"/> + <fbc:geneProductRef fbc:geneProduct="G_DLAT"/> + <fbc:geneProductRef fbc:geneProduct="G_PDHB"/> <fbc:or> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8806"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8807"/> + <fbc:geneProductRef fbc:geneProduct="G_PDHA1"/> + <fbc:geneProductRef fbc:geneProduct="G_PDHA2"/> </fbc:or> </fbc:and> <fbc:and> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2898"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8124"/> - <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2911"/> + <fbc:geneProductRef fbc:geneProduct="G_DLD"/> + <fbc:geneProductRef fbc:geneProduct="G_OGDH"/> + <fbc:geneProductRef fbc:geneProduct="G_DLST"/> </fbc:and> </fbc:or> </fbc:geneProductAssociation> @@ -14699,27 +14699,47 @@ </fbc:objective> </fbc:listOfObjectives> <fbc:listOfGeneProducts> - <fbc:geneProduct fbc:id="G_HGNC__58__11830" fbc:name="G_HGNC:11830" fbc:label="G_HGNC__58__11830"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000167900</p> - <p>HGNC ID: HGNC:11830</p> - <p>HGNC symbol: TK1</p> - <p>entrez_id: 7083</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__11831" fbc:name="G_HGNC:11831" fbc:label="G_HGNC__58__11831"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000166548</p> - <p>HGNC ID: HGNC:11831</p> - <p>HGNC symbol: TK2</p> - <p>entrez_id: 7084</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4925" fbc:name="G_HGNC:4925" fbc:label="G_HGNC__58__4925"> + <fbc:geneProduct fbc:id="G_SLC16A3" fbc:name="G_SLC16A3" fbc:label="G_SLC16A3"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000141526</p> + <p>HGNC ID: HGNC:10924</p> + <p>HGNC symbol: SLC16A3</p> + <p>entrez_id: 9123</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC16A1" fbc:name="G_SLC16A1" fbc:label="G_SLC16A1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000155380</p> + <p>HGNC ID: HGNC:10922</p> + <p>HGNC symbol: SLC16A1</p> + <p>entrez_id: 6566</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC16A7" fbc:name="G_SLC16A7" fbc:label="G_SLC16A7"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000118596</p> + <p>HGNC ID: HGNC:10928</p> + <p>HGNC symbol: SLC16A7</p> + <p>entrez_id: 9194</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_HKDC1" fbc:name="G_HKDC1" fbc:label="G_HKDC1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000156510</p> + <p>HGNC ID: HGNC:23302</p> + <p>HGNC symbol: HKDC1</p> + <p>entrez_id: 80201</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_HK3" fbc:name="G_HK3" fbc:label="G_HK3"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000160883</p> @@ -14729,7 +14749,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4195" fbc:name="G_HGNC:4195" fbc:label="G_HGNC__58__4195"> + <fbc:geneProduct fbc:id="G_GCK" fbc:name="G_GCK" fbc:label="G_GCK"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000106633</p> @@ -14739,17 +14759,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4922" fbc:name="G_HGNC:4922" fbc:label="G_HGNC__58__4922"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000156515</p> - <p>HGNC ID: HGNC:4922</p> - <p>HGNC symbol: HK1</p> - <p>entrez_id: 3098</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4923" fbc:name="G_HGNC:4923" fbc:label="G_HGNC__58__4923"> + <fbc:geneProduct fbc:id="G_HK2" fbc:name="G_HK2" fbc:label="G_HK2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000159399</p> @@ -14759,17 +14769,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__23302" fbc:name="G_HGNC:23302" fbc:label="G_HGNC__58__23302"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000156510</p> - <p>HGNC ID: HGNC:23302</p> - <p>HGNC symbol: HKDC1</p> - <p>entrez_id: 80201</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4056" fbc:name="G_HGNC:4056" fbc:label="G_HGNC__58__4056"> + <fbc:geneProduct fbc:id="G_HK1" fbc:name="G_HK1" fbc:label="G_HK1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000156515</p> + <p>HGNC ID: HGNC:4922</p> + <p>HGNC symbol: HK1</p> + <p>entrez_id: 3098</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_G6PC1" fbc:name="G_G6PC1" fbc:label="G_G6PC1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000131482</p> @@ -14779,7 +14789,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__28906" fbc:name="G_HGNC:28906" fbc:label="G_HGNC__58__28906"> + <fbc:geneProduct fbc:id="G_G6PC2" fbc:name="G_G6PC2" fbc:label="G_G6PC2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000152254</p> @@ -14789,7 +14799,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__24861" fbc:name="G_HGNC:24861" fbc:label="G_HGNC__58__24861"> + <fbc:geneProduct fbc:id="G_G6PC3" fbc:name="G_G6PC3" fbc:label="G_G6PC3"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000141349</p> @@ -14799,7 +14809,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4458" fbc:name="G_HGNC:4458" fbc:label="G_HGNC__58__4458"> + <fbc:geneProduct fbc:id="G_GPI" fbc:name="G_GPI" fbc:label="G_GPI"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000105220</p> @@ -14809,7 +14819,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__8877" fbc:name="G_HGNC:8877" fbc:label="G_HGNC__58__8877"> + <fbc:geneProduct fbc:id="G_PFKL" fbc:name="G_PFKL" fbc:label="G_PFKL"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000141959</p> + <p>HGNC ID: HGNC:8876</p> + <p>HGNC symbol: PFKL</p> + <p>entrez_id: 5211</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_PFKM" fbc:name="G_PFKM" fbc:label="G_PFKM"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000152556</p> @@ -14819,17 +14839,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__8876" fbc:name="G_HGNC:8876" fbc:label="G_HGNC__58__8876"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000141959</p> - <p>HGNC ID: HGNC:8876</p> - <p>HGNC symbol: PFKL</p> - <p>entrez_id: 5211</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__8878" fbc:name="G_HGNC:8878" fbc:label="G_HGNC__58__8878"> + <fbc:geneProduct fbc:id="G_PFKP" fbc:name="G_PFKP" fbc:label="G_PFKP"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000067057</p> @@ -14839,7 +14849,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__3606" fbc:name="G_HGNC:3606" fbc:label="G_HGNC__58__3606"> + <fbc:geneProduct fbc:id="G_FBP2" fbc:name="G_FBP2" fbc:label="G_FBP2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000130957</p> + <p>HGNC ID: HGNC:3607</p> + <p>HGNC symbol: FBP2</p> + <p>entrez_id: 8789</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_FBP1" fbc:name="G_FBP1" fbc:label="G_FBP1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000165140</p> @@ -14849,17 +14869,27 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__3607" fbc:name="G_HGNC:3607" fbc:label="G_HGNC__58__3607"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000130957</p> - <p>HGNC ID: HGNC:3607</p> - <p>HGNC symbol: FBP2</p> - <p>entrez_id: 8789</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__417" fbc:name="G_HGNC:417" fbc:label="G_HGNC__58__417"> + <fbc:geneProduct fbc:id="G_ALDOC" fbc:name="G_ALDOC" fbc:label="G_ALDOC"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000109107</p> + <p>HGNC ID: HGNC:418</p> + <p>HGNC symbol: ALDOC</p> + <p>entrez_id: 230</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ALDOA" fbc:name="G_ALDOA" fbc:label="G_ALDOA"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000149925</p> + <p>HGNC ID: HGNC:414</p> + <p>HGNC symbol: ALDOA</p> + <p>entrez_id: 226</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ALDOB" fbc:name="G_ALDOB" fbc:label="G_ALDOB"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000136872</p> @@ -14869,27 +14899,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__418" fbc:name="G_HGNC:418" fbc:label="G_HGNC__58__418"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000109107</p> - <p>HGNC ID: HGNC:418</p> - <p>HGNC symbol: ALDOC</p> - <p>entrez_id: 230</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__414" fbc:name="G_HGNC:414" fbc:label="G_HGNC__58__414"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000149925</p> - <p>HGNC ID: HGNC:414</p> - <p>HGNC symbol: ALDOA</p> - <p>entrez_id: 226</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__12009" fbc:name="G_HGNC:12009" fbc:label="G_HGNC__58__12009"> + <fbc:geneProduct fbc:id="G_TPI1" fbc:name="G_TPI1" fbc:label="G_TPI1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000111669</p> @@ -14899,7 +14909,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__24864" fbc:name="G_HGNC:24864" fbc:label="G_HGNC__58__24864"> + <fbc:geneProduct fbc:id="G_GAPDHS" fbc:name="G_GAPDHS" fbc:label="G_GAPDHS"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000105679</p> @@ -14909,7 +14919,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4141" fbc:name="G_HGNC:4141" fbc:label="G_HGNC__58__4141"> + <fbc:geneProduct fbc:id="G_GAPDH" fbc:name="G_GAPDH" fbc:label="G_GAPDH"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000111640</p> @@ -14919,7 +14929,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__8896" fbc:name="G_HGNC:8896" fbc:label="G_HGNC__58__8896"> + <fbc:geneProduct fbc:id="G_PGK1" fbc:name="G_PGK1" fbc:label="G_PGK1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000102144</p> @@ -14929,7 +14939,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__8898" fbc:name="G_HGNC:8898" fbc:label="G_HGNC__58__8898"> + <fbc:geneProduct fbc:id="G_PGK2" fbc:name="G_PGK2" fbc:label="G_PGK2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000170950</p> @@ -14939,7 +14949,27 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__8889" fbc:name="G_HGNC:8889" fbc:label="G_HGNC__58__8889"> + <fbc:geneProduct fbc:id="G_BPGM" fbc:name="G_BPGM" fbc:label="G_BPGM"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000172331</p> + <p>HGNC ID: HGNC:1093</p> + <p>HGNC symbol: BPGM</p> + <p>entrez_id: 669</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_PGAM1" fbc:name="G_PGAM1" fbc:label="G_PGAM1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000171314</p> + <p>HGNC ID: HGNC:8888</p> + <p>HGNC symbol: PGAM1</p> + <p>entrez_id: 5223</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_PGAM2" fbc:name="G_PGAM2" fbc:label="G_PGAM2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000164708</p> @@ -14949,27 +14979,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__1093" fbc:name="G_HGNC:1093" fbc:label="G_HGNC__58__1093"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000172331</p> - <p>HGNC ID: HGNC:1093</p> - <p>HGNC symbol: BPGM</p> - <p>entrez_id: 669</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__8888" fbc:name="G_HGNC:8888" fbc:label="G_HGNC__58__8888"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000171314</p> - <p>HGNC ID: HGNC:8888</p> - <p>HGNC symbol: PGAM1</p> - <p>entrez_id: 5223</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__3353" fbc:name="G_HGNC:3353" fbc:label="G_HGNC__58__3353"> + <fbc:geneProduct fbc:id="G_ENO2" fbc:name="G_ENO2" fbc:label="G_ENO2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000111674</p> @@ -14979,17 +14989,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__3350" fbc:name="G_HGNC:3350" fbc:label="G_HGNC__58__3350"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000074800</p> - <p>HGNC ID: HGNC:3350</p> - <p>HGNC symbol: ENO1</p> - <p>entrez_id: 2023</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__3354" fbc:name="G_HGNC:3354" fbc:label="G_HGNC__58__3354"> + <fbc:geneProduct fbc:id="G_ENO3" fbc:name="G_ENO3" fbc:label="G_ENO3"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000108515</p> @@ -14999,7 +14999,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__9021" fbc:name="G_HGNC:9021" fbc:label="G_HGNC__58__9021"> + <fbc:geneProduct fbc:id="G_ENO1" fbc:name="G_ENO1" fbc:label="G_ENO1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000074800</p> + <p>HGNC ID: HGNC:3350</p> + <p>HGNC symbol: ENO1</p> + <p>entrez_id: 2023</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_PKM" fbc:name="G_PKM" fbc:label="G_PKM"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000067225</p> @@ -15009,7 +15019,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__9020" fbc:name="G_HGNC:9020" fbc:label="G_HGNC__58__9020"> + <fbc:geneProduct fbc:id="G_PKLR" fbc:name="G_PKLR" fbc:label="G_PKLR"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000143627</p> @@ -15019,7 +15029,17 @@ </html> </notes> </fbc:geneProduct> - 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fbc:name="G_LDHA" fbc:label="G_LDHA"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000134333</p> + <p>HGNC ID: HGNC:6535</p> + <p>HGNC symbol: LDHA</p> + <p>entrez_id: 3939</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_LDHB" fbc:name="G_LDHB" fbc:label="G_LDHB"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000111716</p> @@ -15079,7 +15079,27 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__9465" fbc:name="G_HGNC:9465" fbc:label="G_HGNC__58__9465"> + <fbc:geneProduct fbc:id="G_LDHAL6A" fbc:name="G_LDHAL6A" fbc:label="G_LDHAL6A"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000166800</p> + <p>HGNC ID: HGNC:28335</p> + <p>HGNC symbol: LDHAL6A</p> + <p>entrez_id: 160287</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_PRPS1" fbc:name="G_PRPS1" fbc:label="G_PRPS1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: 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HGNC:846</p> + <p>HGNC symbol: ATP5ME</p> + <p>entrez_id: 521</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5PD" fbc:name="G_ATP5PD" fbc:label="G_ATP5PD"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000167863</p> @@ -16309,7 +16339,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__833" fbc:name="G_HGNC:833" fbc:label="G_HGNC__58__833"> + <fbc:geneProduct fbc:id="G_ATP5F1C" fbc:name="G_ATP5F1C" fbc:label="G_ATP5F1C"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000165629</p> @@ -16319,7 +16349,57 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__843" fbc:name="G_HGNC:843" fbc:label="G_HGNC__58__843"> + <fbc:geneProduct fbc:id="G_ATP5F1D" fbc:name="G_ATP5F1D" fbc:label="G_ATP5F1D"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000099624</p> + <p>HGNC ID: HGNC:837</p> + <p>HGNC symbol: ATP5F1D</p> + <p>entrez_id: 513</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5MC2" fbc:name="G_ATP5MC2" fbc:label="G_ATP5MC2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000135390</p> + <p>HGNC ID: HGNC:842</p> + <p>HGNC symbol: ATP5MC2</p> + <p>entrez_id: 517</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5MF" fbc:name="G_ATP5MF" fbc:label="G_ATP5MF"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000241468</p> + <p>HGNC ID: HGNC:848</p> + <p>HGNC symbol: ATP5MF</p> + <p>entrez_id: 9551</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5F1A" fbc:name="G_ATP5F1A" fbc:label="G_ATP5F1A"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000152234</p> + <p>HGNC ID: HGNC:823</p> + <p>HGNC symbol: ATP5F1A</p> + <p>entrez_id: 498</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5PB" fbc:name="G_ATP5PB" fbc:label="G_ATP5PB"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000116459</p> + <p>HGNC ID: HGNC:840</p> + <p>HGNC symbol: ATP5PB</p> + <p>entrez_id: 515</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5MC3" fbc:name="G_ATP5MC3" fbc:label="G_ATP5MC3"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000154518</p> @@ -16329,7 +16409,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__838" fbc:name="G_HGNC:838" fbc:label="G_HGNC__58__838"> + <fbc:geneProduct fbc:id="G_ATP5PO" fbc:name="G_ATP5PO" fbc:label="G_ATP5PO"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000241837</p> + <p>HGNC ID: HGNC:850</p> + <p>HGNC symbol: ATP5PO</p> + <p>entrez_id: 539</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5F1E" fbc:name="G_ATP5F1E" fbc:label="G_ATP5F1E"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000124172</p> @@ -16339,47 +16429,7 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<notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000198899</p> @@ -16439,7 +16449,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__14247" fbc:name="G_HGNC:14247" fbc:label="G_HGNC__58__14247"> + <fbc:geneProduct fbc:id="G_MT__45__ATP8" fbc:name="G_MT__45__ATP8" fbc:label="G_MT__45__ATP8"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000228253</p> + <p>HGNC ID: HGNC:7415</p> + <p>HGNC symbol: MT-ATP8</p> + <p>entrez_id: 4509</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5MG" fbc:name="G_ATP5MG" fbc:label="G_ATP5MG"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000167283</p> @@ -16449,17 +16469,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__837" fbc:name="G_HGNC:837" fbc:label="G_HGNC__58__837"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000099624</p> - <p>HGNC ID: HGNC:837</p> - <p>HGNC symbol: 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fbc:id="G_HGNC__58__4624" fbc:name="G_HGNC:4624" fbc:label="G_HGNC__58__4624"> + <fbc:geneProduct fbc:id="G_GSS" fbc:name="G_GSS" fbc:label="G_GSS"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000100983</p> @@ -16489,7 +16499,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__11180" fbc:name="G_HGNC:11180" fbc:label="G_HGNC__58__11180"> + <fbc:geneProduct fbc:id="G_SOD2" fbc:name="G_SOD2" fbc:label="G_SOD2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000291237</p> @@ -16499,7 +16509,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__9352" fbc:name="G_HGNC:9352" fbc:label="G_HGNC__58__9352"> + <fbc:geneProduct fbc:id="G_PRDX1" fbc:name="G_PRDX1" fbc:label="G_PRDX1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000117450</p> @@ -16509,7 +16519,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4553" fbc:name="G_HGNC:4553" fbc:label="G_HGNC__58__4553"> + <fbc:geneProduct fbc:id="G_GPX2" fbc:name="G_GPX2" fbc:label="G_GPX2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000176153</p> + <p>HGNC ID: HGNC:4554</p> + <p>HGNC symbol: GPX2</p> + <p>entrez_id: 2877</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_GPX1" fbc:name="G_GPX1" fbc:label="G_GPX1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000233276</p> @@ -16519,7 +16539,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4556" fbc:name="G_HGNC:4556" fbc:label="G_HGNC__58__4556"> + <fbc:geneProduct fbc:id="G_PRDX2" fbc:name="G_PRDX2" fbc:label="G_PRDX2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000167815</p> + <p>HGNC ID: HGNC:9353</p> + <p>HGNC symbol: PRDX2</p> + <p>entrez_id: 7001</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_GPX4" fbc:name="G_GPX4" fbc:label="G_GPX4"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000167468</p> @@ -16529,27 +16559,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__9353" fbc:name="G_HGNC:9353" fbc:label="G_HGNC__58__9353"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000167815</p> - <p>HGNC ID: HGNC:9353</p> - <p>HGNC symbol: PRDX2</p> - <p>entrez_id: 7001</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4554" fbc:name="G_HGNC:4554" fbc:label="G_HGNC__58__4554"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000176153</p> - <p>HGNC ID: HGNC:4554</p> - <p>HGNC symbol: GPX2</p> - <p>entrez_id: 2877</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__9354" fbc:name="G_HGNC:9354" fbc:label="G_HGNC__58__9354"> + <fbc:geneProduct fbc:id="G_PRDX3" fbc:name="G_PRDX3" fbc:label="G_PRDX3"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000165672</p> @@ 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CA14</p> + <p>entrez_id: 23632</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_CA13" fbc:name="G_CA13" fbc:label="G_CA13"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000185015</p> + <p>HGNC ID: HGNC:14914</p> + <p>HGNC symbol: CA13</p> + <p>entrez_id: 377677</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_CA12" fbc:name="G_CA12" fbc:label="G_CA12"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000074410</p> @@ -16679,17 +16719,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__1372" fbc:name="G_HGNC:1372" fbc:label="G_HGNC__58__1372"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000118298</p> - <p>HGNC ID: HGNC:1372</p> - <p>HGNC symbol: CA14</p> - <p>entrez_id: 23632</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__1368" fbc:name="G_HGNC:1368" fbc:label="G_HGNC__58__1368"> + 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fbc:label="G_HGNC__58__1377"> + <fbc:geneProduct fbc:id="G_CA5A" fbc:name="G_CA5A" fbc:label="G_CA5A"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000174990</p> @@ -16779,7 +16779,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__1378" fbc:name="G_HGNC:1378" fbc:label="G_HGNC__58__1378"> + <fbc:geneProduct fbc:id="G_CA5B" fbc:name="G_CA5B" fbc:label="G_CA5B"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000169239</p> @@ -16789,7 +16789,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4331" fbc:name="G_HGNC:4331" fbc:label="G_HGNC__58__4331"> + <fbc:geneProduct fbc:id="G_GLS" fbc:name="G_GLS" fbc:label="G_GLS"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000115419</p> @@ -16799,17 +16799,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4341" fbc:name="G_HGNC:4341" fbc:label="G_HGNC__58__4341"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000135821</p> - <p>HGNC ID: HGNC:4341</p> - <p>HGNC symbol: GLUL</p> - <p>entrez_id: 2752</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__21016" fbc:name="G_HGNC:21016" fbc:label="G_HGNC__58__21016"> + <fbc:geneProduct fbc:id="G_LGSN" fbc:name="G_LGSN" fbc:label="G_LGSN"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000146166</p> @@ -16819,17 +16809,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__10988" fbc:name="G_HGNC:10988" fbc:label="G_HGNC__58__10988"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000182902</p> - <p>HGNC ID: HGNC:10988</p> - <p>HGNC symbol: SLC25A18</p> - <p>entrez_id: 83733</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__19954" fbc:name="G_HGNC:19954" fbc:label="G_HGNC__58__19954"> + <fbc:geneProduct fbc:id="G_GLUL" fbc:name="G_GLUL" fbc:label="G_GLUL"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000135821</p> + <p>HGNC ID: HGNC:4341</p> + <p>HGNC symbol: GLUL</p> + <p>entrez_id: 2752</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC25A22" fbc:name="G_SLC25A22" fbc:label="G_SLC25A22"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000177542</p> @@ -16839,7 +16829,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__29570" fbc:name="G_HGNC:29570" fbc:label="G_HGNC__58__29570"> + <fbc:geneProduct fbc:id="G_SLC25A18" fbc:name="G_SLC25A18" fbc:label="G_SLC25A18"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000182902</p> + <p>HGNC ID: HGNC:10988</p> + <p>HGNC symbol: SLC25A18</p> + <p>entrez_id: 83733</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_GLS2" fbc:name="G_GLS2" fbc:label="G_GLS2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000135423</p> @@ -16849,7 +16849,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__9238" fbc:name="G_HGNC:9238" fbc:label="G_HGNC__58__9238"> + <fbc:geneProduct fbc:id="G_PPAT" fbc:name="G_PPAT" fbc:label="G_PPAT"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000128059</p> @@ -16859,7 +16859,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4163" fbc:name="G_HGNC:4163" fbc:label="G_HGNC__58__4163"> + <fbc:geneProduct fbc:id="G_GART" fbc:name="G_GART" fbc:label="G_GART"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000159131</p> @@ -16869,7 +16869,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__8863" fbc:name="G_HGNC:8863" fbc:label="G_HGNC__58__8863"> + <fbc:geneProduct fbc:id="G_PFAS" fbc:name="G_PFAS" fbc:label="G_PFAS"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000178921</p> @@ -16879,7 +16879,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__8587" fbc:name="G_HGNC:8587" fbc:label="G_HGNC__58__8587"> + <fbc:geneProduct fbc:id="G_PAICS" fbc:name="G_PAICS" fbc:label="G_PAICS"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000128050</p> @@ -16889,7 +16889,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__291" fbc:name="G_HGNC:291" fbc:label="G_HGNC__58__291"> + <fbc:geneProduct fbc:id="G_ADSL" fbc:name="G_ADSL" fbc:label="G_ADSL"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000239900</p> @@ -16899,7 +16899,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__794" fbc:name="G_HGNC:794" fbc:label="G_HGNC__58__794"> + <fbc:geneProduct fbc:id="G_ATIC" fbc:name="G_ATIC" fbc:label="G_ATIC"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000138363</p> @@ -16909,7 +16909,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__20093" fbc:name="G_HGNC:20093" fbc:label="G_HGNC__58__20093"> + <fbc:geneProduct fbc:id="G_ADSS1" fbc:name="G_ADSS1" fbc:label="G_ADSS1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000185100</p> @@ -16919,7 +16919,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__292" fbc:name="G_HGNC:292" fbc:label="G_HGNC__58__292"> + <fbc:geneProduct fbc:id="G_ADSS2" fbc:name="G_ADSS2" fbc:label="G_ADSS2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000035687</p> @@ -16929,7 +16929,37 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4693" fbc:name="G_HGNC:4693" fbc:label="G_HGNC__58__4693"> + <fbc:geneProduct fbc:id="G_IMPDH2" fbc:name="G_IMPDH2" fbc:label="G_IMPDH2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000178035</p> + <p>HGNC ID: HGNC:6053</p> + <p>HGNC symbol: IMPDH2</p> + <p>entrez_id: 3615</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_IMPDH1" fbc:name="G_IMPDH1" fbc:label="G_IMPDH1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000106348</p> + <p>HGNC ID: HGNC:6052</p> + <p>HGNC symbol: IMPDH1</p> + <p>entrez_id: 3614</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_GMPS" fbc:name="G_GMPS" fbc:label="G_GMPS"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000163655</p> + <p>HGNC ID: HGNC:4378</p> + <p>HGNC symbol: GMPS</p> + <p>entrez_id: 8833</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_GUK1" fbc:name="G_GUK1" fbc:label="G_GUK1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000143774</p> @@ -16939,17 +16969,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__17296" fbc:name="G_HGNC:17296" fbc:label="G_HGNC__58__17296"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000048392</p> - <p>HGNC ID: HGNC:17296</p> - <p>HGNC symbol: RRM2B</p> - 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</notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__406" fbc:name="G_HGNC:406" fbc:label="G_HGNC__58__406"> + <fbc:geneProduct fbc:id="G_ALDH4A1" fbc:name="G_ALDH4A1" fbc:label="G_ALDH4A1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000159423</p> @@ -17389,7 +17439,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__30262" fbc:name="G_HGNC:30262" fbc:label="G_HGNC__58__30262"> + <fbc:geneProduct fbc:id="G_PYCR2" fbc:name="G_PYCR2" fbc:label="G_PYCR2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000143811</p> @@ -17399,7 +17449,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__17325" fbc:name="G_HGNC:17325" fbc:label="G_HGNC__58__17325"> + <fbc:geneProduct fbc:id="G_PRODH2" fbc:name="G_PRODH2" fbc:label="G_PRODH2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000250799</p> @@ -17409,7 +17459,7 @@ </html> </notes> </fbc:geneProduct> - 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fbc:name="G_HGNC:7468" fbc:label="G_HGNC__58__7468"> + <fbc:geneProduct fbc:id="G_ASRGL1" fbc:name="G_ASRGL1" fbc:label="G_ASRGL1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000162174</p> + <p>HGNC ID: HGNC:16448</p> + <p>HGNC symbol: ASRGL1</p> + <p>entrez_id: 80150</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_MTR" fbc:name="G_MTR" fbc:label="G_MTR"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000116984</p> @@ -17449,7 +17499,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__6904" fbc:name="G_HGNC:6904" fbc:label="G_HGNC__58__6904"> + <fbc:geneProduct fbc:id="G_MAT1A" fbc:name="G_MAT1A" fbc:label="G_MAT1A"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000151224</p> + <p>HGNC ID: HGNC:6903</p> + <p>HGNC symbol: MAT1A</p> + <p>entrez_id: 4143</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_MAT2A" fbc:name="G_MAT2A" fbc:label="G_MAT2A"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000168906</p> @@ -17459,7 +17519,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__6905" fbc:name="G_HGNC:6905" fbc:label="G_HGNC__58__6905"> + <fbc:geneProduct fbc:id="G_MAT2B" fbc:name="G_MAT2B" fbc:label="G_MAT2B"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000038274</p> @@ -17469,17 +17529,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__6903" fbc:name="G_HGNC:6903" fbc:label="G_HGNC__58__6903"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000151224</p> - <p>HGNC ID: HGNC:6903</p> - <p>HGNC symbol: MAT1A</p> - <p>entrez_id: 4143</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__257" fbc:name="G_HGNC:257" fbc:label="G_HGNC__58__257"> + <fbc:geneProduct fbc:id="G_HNMT" fbc:name="G_HNMT" fbc:label="G_HNMT"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000150540</p> + <p>HGNC ID: HGNC:5028</p> + <p>HGNC symbol: HNMT</p> + <p>entrez_id: 3176</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ADK" fbc:name="G_ADK" fbc:label="G_ADK"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000156110</p> @@ -17489,7 +17549,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__1550" fbc:name="G_HGNC:1550" fbc:label="G_HGNC__58__1550"> + <fbc:geneProduct fbc:id="G_CBS" fbc:name="G_CBS" fbc:label="G_CBS"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000160200</p> @@ -17499,7 +17559,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__2501" fbc:name="G_HGNC:2501" fbc:label="G_HGNC__58__2501"> + <fbc:geneProduct fbc:id="G_CTH" fbc:name="G_CTH" fbc:label="G_CTH"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000116761</p> @@ -17509,7 +17569,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__7436" fbc:name="G_HGNC:7436" fbc:label="G_HGNC__58__7436"> + <fbc:geneProduct fbc:id="G_MTHFR" fbc:name="G_MTHFR" fbc:label="G_MTHFR"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000177000</p> @@ -17519,7 +17579,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__3791" fbc:name="G_HGNC:3791" fbc:label="G_HGNC__58__3791"> + <fbc:geneProduct fbc:id="G_FOLR3" fbc:name="G_FOLR3" fbc:label="G_FOLR3"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000110203</p> + <p>HGNC ID: HGNC:3795</p> + <p>HGNC symbol: FOLR3</p> + <p>entrez_id: 2352</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_FOLR1" fbc:name="G_FOLR1" fbc:label="G_FOLR1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000110195</p> @@ -17529,17 +17599,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__3795" 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xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000137992</p> + <p>HGNC ID: HGNC:2698</p> + <p>HGNC symbol: DBT</p> + <p>entrez_id: 1629</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_BCKDHA" fbc:name="G_BCKDHA" fbc:label="G_BCKDHA"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000248098</p> + <p>HGNC ID: HGNC:986</p> + <p>HGNC symbol: BCKDHA</p> + <p>entrez_id: 593</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_IVD" fbc:name="G_IVD" fbc:label="G_IVD"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000128928</p> @@ -17599,7 +17659,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__6937" fbc:name="G_HGNC:6937" fbc:label="G_HGNC__58__6937"> + <fbc:geneProduct fbc:id="G_MCCC1" fbc:name="G_MCCC1" fbc:label="G_MCCC1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000078070</p> + <p>HGNC ID: HGNC:6936</p> + <p>HGNC symbol: MCCC1</p> + <p>entrez_id: 56922</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_MCCC2" fbc:name="G_MCCC2" fbc:label="G_MCCC2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000131844</p> @@ -17609,17 +17679,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__6936" fbc:name="G_HGNC:6936" fbc:label="G_HGNC__58__6936"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000078070</p> - <p>HGNC ID: HGNC:6936</p> - <p>HGNC symbol: MCCC1</p> - <p>entrez_id: 56922</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__890" fbc:name="G_HGNC:890" fbc:label="G_HGNC__58__890"> + <fbc:geneProduct fbc:id="G_AUH" fbc:name="G_AUH" fbc:label="G_AUH"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000148090</p> @@ -17629,7 +17689,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__87" fbc:name="G_HGNC:87" fbc:label="G_HGNC__58__87"> + <fbc:geneProduct fbc:id="G_ACADM" fbc:name="G_ACADM" fbc:label="G_ACADM"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000117054</p> + <p>HGNC ID: HGNC:89</p> + <p>HGNC symbol: ACADM</p> + <p>entrez_id: 34</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ACAD8" fbc:name="G_ACAD8" fbc:label="G_ACAD8"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000151498</p> @@ -17639,17 +17709,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__89" fbc:name="G_HGNC:89" fbc:label="G_HGNC__58__89"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000117054</p> - <p>HGNC ID: HGNC:89</p> - <p>HGNC symbol: ACADM</p> - <p>entrez_id: 34</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4801" fbc:name="G_HGNC:4801" fbc:label="G_HGNC__58__4801"> + <fbc:geneProduct fbc:id="G_HADHA" fbc:name="G_HADHA" fbc:label="G_HADHA"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000084754</p> @@ -17659,7 +17719,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4803" fbc:name="G_HGNC:4803" fbc:label="G_HGNC__58__4803"> + <fbc:geneProduct fbc:id="G_HADHB" fbc:name="G_HADHB" fbc:label="G_HADHB"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000138029</p> @@ -17669,7 +17729,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__3151" fbc:name="G_HGNC:3151" fbc:label="G_HGNC__58__3151"> + <fbc:geneProduct fbc:id="G_ECHS1" fbc:name="G_ECHS1" fbc:label="G_ECHS1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000127884</p> @@ -17679,7 +17739,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4907" fbc:name="G_HGNC:4907" fbc:label="G_HGNC__58__4907"> + <fbc:geneProduct fbc:id="G_HIBADH" fbc:name="G_HIBADH" fbc:label="G_HIBADH"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> 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xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000278550</p> + <p>HGNC ID: HGNC:23087</p> + <p>HGNC symbol: SLC43A2</p> + <p>entrez_id: 124935</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC16A10" fbc:name="G_SLC16A10" fbc:label="G_SLC16A10"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000112394</p> @@ -18519,7 +18889,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__18761" fbc:name="G_HGNC:18761" fbc:label="G_HGNC__58__18761"> + <fbc:geneProduct fbc:id="G_SLC22A5" fbc:name="G_SLC22A5" fbc:label="G_SLC22A5"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000197375</p> + <p>HGNC ID: HGNC:10969</p> + <p>HGNC symbol: SLC22A5</p> + <p>entrez_id: 6584</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC36A1" fbc:name="G_SLC36A1" fbc:label="G_SLC36A1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000123643</p> @@ -18529,17 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- <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000092068</p> - <p>HGNC ID: HGNC:11066</p> - <p>HGNC symbol: SLC7A8</p> - <p>entrez_id: 23428</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__11054" fbc:name="G_HGNC:11054" fbc:label="G_HGNC__58__11054"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000011083</p> - <p>HGNC ID: HGNC:11054</p> - <p>HGNC symbol: SLC6A7</p> - <p>entrez_id: 6534</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__30927" fbc:name="G_HGNC:30927" fbc:label="G_HGNC__58__30927"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000163817</p> - <p>HGNC ID: HGNC:30927</p> - <p>HGNC symbol: SLC6A20</p> - <p>entrez_id: 54716</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__11025" fbc:name="G_HGNC:11025" fbc:label="G_HGNC__58__11025"> + <fbc:geneProduct fbc:id="G_SLC3A1" fbc:name="G_SLC3A1" fbc:label="G_SLC3A1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000138079</p> @@ -19529,7 +19639,7 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__11059" fbc:name="G_HGNC:11059" fbc:label="G_HGNC__58__11059"> + <fbc:geneProduct fbc:id="G_SLC7A11" fbc:name="G_SLC7A11" fbc:label="G_SLC7A11"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000151012</p> @@ -19539,117 +19649,17 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__8582" fbc:name="G_HGNC:8582" fbc:label="G_HGNC__58__8582"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000171759</p> - <p>HGNC ID: HGNC:8582</p> - <p>HGNC symbol: PAH</p> - <p>entrez_id: 5053</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__10963" fbc:name="G_HGNC:10963" fbc:label="G_HGNC__58__10963"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000175003</p> - <p>HGNC ID: HGNC:10963</p> - <p>HGNC symbol: SLC22A1</p> - <p>entrez_id: 6580</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__5028" fbc:name="G_HGNC:5028" fbc:label="G_HGNC__58__5028"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000150540</p> - <p>HGNC ID: HGNC:5028</p> - <p>HGNC symbol: HNMT</p> - <p>entrez_id: 3176</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__2859" fbc:name="G_HGNC:2859" fbc:label="G_HGNC__58__2859"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000116133</p> - <p>HGNC ID: HGNC:2859</p> - <p>HGNC symbol: DHCR24</p> - <p>entrez_id: 1718</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4093" fbc:name="G_HGNC:4093" fbc:label="G_HGNC__58__4093"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000136750</p> - <p>HGNC ID: HGNC:4093</p> - <p>HGNC symbol: GAD2</p> - <p>entrez_id: 2572</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4799" fbc:name="G_HGNC:4799" fbc:label="G_HGNC__58__4799"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000138796</p> - <p>HGNC ID: HGNC:4799</p> - <p>HGNC symbol: HADH</p> - <p>entrez_id: 3033</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__4800" fbc:name="G_HGNC:4800" fbc:label="G_HGNC__58__4800"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000072506</p> - <p>HGNC ID: HGNC:4800</p> - <p>HGNC symbol: HSD17B10</p> - <p>entrez_id: 3028</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__20910" fbc:name="G_HGNC:20910" fbc:label="G_HGNC__58__20910"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000183077</p> - <p>HGNC ID: HGNC:20910</p> - <p>HGNC symbol: AFMID</p> - <p>entrez_id: 125061</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__27269" fbc:name="G_HGNC:27269" fbc:label="G_HGNC__58__27269"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000188676</p> - <p>HGNC ID: HGNC:27269</p> - <p>HGNC symbol: IDO2</p> - <p>entrez_id: 169355</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__6059" fbc:name="G_HGNC:6059" fbc:label="G_HGNC__58__6059"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000131203</p> - <p>HGNC ID: HGNC:6059</p> - <p>HGNC symbol: IDO1</p> - <p>entrez_id: 3620</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__11708" fbc:name="G_HGNC:11708" fbc:label="G_HGNC__58__11708"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000151790</p> - <p>HGNC ID: HGNC:11708</p> - <p>HGNC symbol: TDO2</p> - <p>entrez_id: 6999</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__15814" fbc:name="G_HGNC__58__15814" fbc:label="G_HGNC__58__15814"> + <fbc:geneProduct fbc:id="G_CRAT" fbc:name="G_CRAT" fbc:label="G_CRAT"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000095321</p> + <p>HGNC ID: HGNC:2342</p> + <p>HGNC symbol: CRAT</p> + <p>entrez_id: 1384</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ACSS2" fbc:name="G_ACSS2" fbc:label="G_ACSS2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> <p>ENSG: ENSG00000131069</p> @@ -19659,26 +19669,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__2342" fbc:name="G_HGNC__58__2342" fbc:label="G_HGNC__58__2342"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000095321</p> - <p>HGNC ID: HGNC:2342</p> - <p>HGNC symbol: CRAT</p> - <p>entrez_id: 1384</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HGNC__58__18355" fbc:name="G_HGNC__58__18355" fbc:label="G_HGNC__58__18355"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000125246</p> - <p>HGNC ID: HGNC:18355</p> - <p>HGNC symbol: CLYBL</p> - <p>entrez_id: 171425</p> - </html> - </notes> - </fbc:geneProduct> </fbc:listOfGeneProducts> </model> </sbml>
--- a/COBRAxy/marea_cluster.py Wed Sep 10 16:50:16 2025 +0000 +++ b/COBRAxy/marea_cluster.py Thu Sep 11 09:03:10 2025 +0000 @@ -507,7 +507,7 @@ if not os.path.exists(args.output_path): os.makedirs(args.output_path) - + #Data read X = read_dataset(args.input) @@ -520,7 +520,7 @@ if any(val is None or np.isnan(val) for val in X[i]): X = X.drop(columns=[i]) - if args.scaling == True: + if args.scaling == "true": list_to_remove = [] toll_std=1e-8 for i in X.columns:
--- a/COBRAxy/utils/model_utils.py Wed Sep 10 16:50:16 2025 +0000 +++ b/COBRAxy/utils/model_utils.py Thu Sep 11 09:03:10 2025 +0000 @@ -444,8 +444,6 @@ return model2 - - # ---------- Utility helpers ---------- def _normalize_colname(col: str) -> str: return col.strip().lower().replace(' ', '_') @@ -461,7 +459,7 @@ candidates = { 'ensg': ['ensg', 'ensembl_gene_id', 'ensembl'], 'hgnc_id': ['hgnc_id', 'hgnc', 'hgnc:'], - 'hgnc_symbol': ['hgnc_symbol', 'hgnc_symbol', 'symbol'], + 'hgnc_symbol': ['hgnc_symbol', 'hgnc symbol', 'symbol'], 'entrez_id': ['entrez', 'entrez_id', 'entrezgene'] } for key, names in candidates.items():