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16
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1 p(HGNC:FOXO3,pmod(P,S,253)) directlyDecreases tscript(p(HGNC:FOXO3))
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2 p(HGNC:FLOT2) decreases p(HGNC:FAS)
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3 p(HGNC:FLOT2) increases p(HGNC:XIAP)
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4 p(HGNC:FLOT2) increases p(HGNC:BIRC5)
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5 p(HGNC:FLOT2) decreases cat(p(HGNC:CASP8))
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6 p(HGNC:FLOT2) decreases cat(p(HGNC:CASP3))
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7 p(HGNC:PDGFA) increases p(HGNC:FOXO3,pmod(P,S,253))
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8 p(HGNC:IL6) increases p(HGNC:BAX)
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9 p(HGNC:IL6) increases p(HGNC:STAT3)
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10 p(HGNC:SIRT1) increases p(HGNC:RELA,pmod(A))
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11 p(HGNC:SIRT1) association p(HGNC:PARP1)
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12 p(HGNC:XRCC6) decreases cat(p(HGNC:BAX))
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13 p(HGNC:STAT3) decreases cat(p(HGNC:CASP7))
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14 p(HGNC:STAT3) decreases cat(p(HGNC:CASP3))
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15 p(SFAM:"FOXO Family") actsIn tscript(p(SFAM:"FOXO Family"))
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16 cat(p(HGNC:CASP10)) increases cat(p(HGNC:CASP3))
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17 p(HGNC:FOXO1,pmod(P,S,256)) directlyDecreases tscript(p(HGNC:FOXO1))
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18 complex(p(HGNC:APAF1),p(HGNC:CYCS),p(HGNC:CASP9)) hasComponent p(HGNC:CYCS)
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19 complex(p(HGNC:APAF1),p(HGNC:CYCS),p(HGNC:CASP9)) hasComponent p(HGNC:APAF1)
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20 complex(p(HGNC:APAF1),p(HGNC:CYCS),p(HGNC:CASP9)) hasComponent p(HGNC:CASP9)
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21 complex(p(HGNC:APAF1),p(HGNC:CYCS),p(HGNC:CASP9)) increases cat(p(HGNC:CASP9))
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22 p(SFAM:"PRKA Family") actsIn kin(p(SFAM:"PRKA Family"))
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23 p(HGNC:MARCKS) hasModification p(HGNC:MARCKS,pmod(P,S,163))
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24 cat(p(HGNC:CASP7)) directlyDecreases p(HGNC:PARP1)
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25 tscript(complex(SCOMP:"Nfkb Complex")) directlyIncreases p(HGNC:BCL2)
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26 tscript(complex(SCOMP:"Nfkb Complex")) increases p(HGNC:BIRC2)
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27 tscript(complex(SCOMP:"Nfkb Complex")) increases p(HGNC:BIRC3)
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28 tscript(complex(SCOMP:"Nfkb Complex")) directlyIncreases p(HGNC:BCL2L1)
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29 tscript(complex(SCOMP:"Nfkb Complex")) directlyIncreases p(HGNC:XIAP)
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30 tscript(complex(SCOMP:"Nfkb Complex")) increases p(HGNC:CFLAR)
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31 tscript(complex(SCOMP:"Nfkb Complex")) increases p(HGNC:BCL2A1)
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32 tscript(complex(SCOMP:"Nfkb Complex")) increases p(HGNC:BIRC5)
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33 tscript(p(HGNC:XBP1)) increases bp(GOBP:"ER-associated ubiquitin-dependent protein catabolic process")
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34 p(HGNC:FAS) actsIn cat(p(HGNC:FAS))
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35 kin(p(HGNC:PRKCA)) directlyIncreases p(HGNC:PRKD1,pmod(P,S,742))
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36 kin(p(HGNC:PRKCA)) directlyIncreases p(HGNC:PRKCA,pmod(P,T,638))
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37 kin(p(HGNC:PRKCA)) directlyIncreases p(HGNC:PRKD1,pmod(P,S,738))
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38 kin(p(HGNC:PRKCA)) directlyIncreases p(HGNC:MARCKS,pmod(P,S,159))
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39 cat(p(HGNC:ERN1)) directlyIncreases p(HGNC:XBP1)
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40 p(HGNC:PRKCD) actsIn kin(p(HGNC:PRKCD))
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41 p(HGNC:MAP2K7) actsIn kin(p(HGNC:MAP2K7))
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42 p(HGNC:MAPK1) actsIn kin(p(HGNC:MAPK1))
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43 cat(p(HGNC:CASP3)) directlyDecreases cat(p(HGNC:BCL2))
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44 cat(p(HGNC:CASP3)) directlyIncreases cat(p(HGNC:ACIN1))
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45 cat(p(HGNC:CASP3)) increases kin(p(HGNC:ROCK1))
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46 cat(p(HGNC:CASP3)) directlyIncreases deg(p(HGNC:LMNB2))
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47 cat(p(HGNC:CASP3)) increases bp(MESHPP:Apoptosis)
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48 cat(p(HGNC:CASP3)) increases cat(p(HGNC:CASP7))
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49 cat(p(HGNC:CASP3)) directlyIncreases cat(p(HGNC:GAS2))
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50 cat(p(HGNC:CASP3)) increases deg(p(HGNC:LMNA))
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51 cat(p(HGNC:CASP3)) directlyDecreases cat(p(HGNC:DFFA))
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52 cat(p(HGNC:CASP3)) directlyIncreases kin(p(HGNC:BMX))
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53 cat(p(HGNC:CASP3)) directlyIncreases cat(p(HGNC:CASP2))
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54 cat(p(HGNC:CASP3)) directlyIncreases deg(p(HGNC:LMNB1))
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55 cat(p(HGNC:CASP3)) directlyDecreases cat(p(HGNC:BCL2L1))
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56 cat(p(HGNC:CASP3)) increases path(MESHD:Emphysema)
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57 cat(p(HGNC:CASP3)) directlyIncreases kin(p(HGNC:PAK2))
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58 cat(p(HGNC:CASP3)) decreases p(HGNC:PARP1)
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59 p(HGNC:IKBKB) hasModification p(HGNC:IKBKB,pmod(P,S,177))
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60 cat(p(HGNC:TNFRSF10B)) increases cat(p(HGNC:TRAF2))
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61 p(HGNC:MAP3K7) hasModification p(HGNC:MAP3K7,pmod(U,K,158))
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62 p(HGNC:ACIN1) actsIn cat(p(HGNC:ACIN1))
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63 p(HGNC:XIAP) decreases bp(MESHPP:Apoptosis)
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64 p(HGNC:XIAP) actsIn cat(p(HGNC:XIAP))
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65 p(HGNC:NFKBIA,pmod(P,S,36)) directlyIncreases deg(p(HGNC:NFKBIA))
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66 kin(p(HGNC:CHUK)) decreases p(HGNC:NFKBIE)
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67 complex(p(HGNC:RIPK1),p(HGNC:TNFRSF10A)) hasComponent p(HGNC:TNFRSF10A)
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68 complex(p(HGNC:RIPK1),p(HGNC:TNFRSF10A)) hasComponent p(HGNC:RIPK1)
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69 p(HGNC:PPP1R15A) increases bp(GOBP:"cell death")
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70 p(HGNC:TNFRSF10B) actsIn cat(p(HGNC:TNFRSF10B))
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71 complex(SCOMP:"Nfkb Complex") hasComponent p(HGNC:NFKB2)
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72 kin(p(SFAM:"PIK3C Class IA Family")) increases kin(p(HGNC:MAPK1))
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73 kin(p(SFAM:"PIK3C Class IA Family")) increases p(HGNC:AKT1,pmod(P,T,308))
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74 kin(p(SFAM:"PIK3C Class IA Family")) increases p(HGNC:AKT1,pmod(P,S,473))
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75 kin(p(SFAM:"PIK3C Class IA Family")) increases kin(p(SFAM:"AKT Family"))
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76 kin(p(SFAM:"PIK3C Class IA Family")) directlyIncreases a(SCHEM:"Phosphatidylinositol-3,4,5-trisphosphate")
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77 kin(p(SFAM:"PIK3C Class IA Family")) increases kin(p(HGNC:MAPK3))
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78 cat(p(HGNC:DIABLO)) decreases cat(p(HGNC:XIAP))
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79 complex(SCOMP:"Nfkb Complex") actsIn tscript(complex(SCOMP:"Nfkb Complex"))
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80 complex(SCOMP:"Nfkb Complex") hasComponent p(HGNC:NFKB1)
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81 complex(SCOMP:"Nfkb Complex") hasComponent p(HGNC:REL)
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82 complex(SCOMP:"Nfkb Complex") hasComponent p(HGNC:RELB)
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83 p(HGNC:FOXO3) hasModification p(HGNC:FOXO3,pmod(P,S,253))
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84 p(HGNC:FOXO3) actsIn tscript(p(HGNC:FOXO3))
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85 p(HGNC:MAP3K1,pmod(P,S,994)) directlyIncreases kin(p(HGNC:MAP3K1))
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86 kin(p(HGNC:PAK2)) increases bp(MESHPP:Apoptosis)
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87 p(HGNC:DIABLO) actsIn cat(p(HGNC:DIABLO))
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88 cat(p(HGNC:BAK1)) increases tport(complex(GOCC:"mitochondrial permeability transition pore complex"))
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89 p(HGNC:IKBKB) actsIn kin(p(HGNC:IKBKB))
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90 cat(p(HGNC:TNFRSF1B)) increases cat(p(HGNC:TRAF2))
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91 cat(p(HGNC:TRAF2)) increases kin(p(HGNC:MAP3K5))
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92 cat(p(HGNC:TRAF2)) increases p(HGNC:MAP3K7,pmod(U,K,158))
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93 cat(p(HGNC:TRAF2)) directlyIncreases kin(p(HGNC:MAP3K7))
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94 cat(p(HGNC:TRAF2)) increases kin(p(HGNC:MAP3K14))
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95 cat(p(HGNC:BAD)) increases bp(MESHPP:Apoptosis)
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96 cat(p(HGNC:BAD)) increases cat(p(HGNC:BAX))
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97 cat(p(HGNC:BAD)) increases cat(p(HGNC:BAK1))
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98 p(HGNC:ATF4) actsIn tscript(p(HGNC:ATF4))
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99 kin(p(HGNC:PRKCE)) directlyIncreases p(HGNC:ELK1,pmod(P,S,383))
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100 kin(p(HGNC:ROCK1)) increases bp(MESHPP:Apoptosis)
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101 p(HGNC:RPS6KA1) actsIn kin(p(HGNC:RPS6KA1))
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102 bp(GOBP:"response to endoplasmic reticulum stress") increases bp(GOBP:"response to unfolded protein")
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103 bp(GOBP:"response to endoplasmic reticulum stress") increases kin(p(HGNC:EIF2AK3))
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104 p(HGNC:PCNA) decreases bp(MESHPP:Apoptosis)
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105 p(HGNC:PDPK1) actsIn kin(p(HGNC:PDPK1))
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106 p(HGNC:PRKCZ) actsIn kin(p(HGNC:PRKCZ))
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107 kin(p(SFAM:"PRKC Family")) directlyIncreases p(HGNC:MARCKS,pmod(P,S,163))
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108 p(HGNC:TRAF2) actsIn cat(p(HGNC:TRAF2))
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109 bp(GOBP:"response to unfolded protein") increases cat(p(HGNC:ERN1))
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110 bp(GOBP:"response to unfolded protein") directlyDecreases complex(p(HGNC:HSPA5),p(HGNC:ERN1))
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111 bp(GOBP:"response to unfolded protein") directlyDecreases complex(p(HGNC:HSPA5),p(HGNC:EIF2AK3))
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112 p(HGNC:MAP3K14) actsIn kin(p(HGNC:MAP3K14))
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113 p(HGNC:DFFA) actsIn cat(p(HGNC:DFFA))
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114 cat(p(HGNC:BBC3)) increases cat(p(HGNC:BAK1))
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115 cat(p(HGNC:BBC3)) directlyIncreases cat(p(HGNC:BAX))
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116 p(HGNC:EIF2AK3) actsIn kin(p(HGNC:EIF2AK3))
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117 p(HGNC:ENDOG) increases bp(MESHPP:Apoptosis)
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118 p(HGNC:BAX,pmod(P,S,184)) directlyDecreases cat(p(HGNC:BAX))
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119 p(HGNC:HTRA2) increases bp(MESHPP:Apoptosis)
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120 p(HGNC:HTRA2) actsIn cat(p(HGNC:HTRA2))
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121 p(HGNC:BMX) actsIn kin(p(HGNC:BMX))
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122 p(HGNC:PTEN) actsIn phos(p(HGNC:PTEN))
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123 p(HGNC:NFKBIA) actsIn kin(p(HGNC:NFKBIA))
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124 tport(complex(GOCC:"mitochondrial permeability transition pore complex")) increases bp(MESHPP:Apoptosis)
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125 p(HGNC:MAP3K5) actsIn kin(p(HGNC:MAP3K5))
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126 p(HGNC:TP53) actsIn tscript(p(HGNC:TP53))
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127 kin(p(HGNC:MAPK3)) decreases cat(p(HGNC:BAD))
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128 kin(p(HGNC:MAPK3)) directlyIncreases p(HGNC:BCL2L11,pmod(P,S,69))
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129 kin(p(HGNC:MAPK3)) directlyIncreases p(HGNC:CASP9,pmod(P,T,125))
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130 kin(p(HGNC:PRKCD)) increases p(HGNC:BAX)
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131 kin(p(HGNC:PRKCD)) directlyIncreases p(HGNC:PRKD1,pmod(P,S,742))
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132 kin(p(HGNC:PRKCD)) directlyIncreases p(HGNC:PRKD1,pmod(P,S,738))
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133 p(HGNC:PTEN,pmod(P,T,383)) directlyDecreases phos(p(HGNC:PTEN))
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134 p(HGNC:AIFM1) increases bp(MESHPP:Apoptosis)
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135 p(HGNC:RELA) hasModification p(HGNC:RELA,pmod(A))
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136 p(HGNC:RELA) hasComponent complex(SCOMP:"Nfkb Complex")
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137 p(HGNC:ERN1) actsIn cat(p(HGNC:ERN1))
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138 cat(p(HGNC:CASP9)) directlyIncreases cat(p(HGNC:CASP3))
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139 cat(p(HGNC:CASP9)) directlyIncreases cat(p(HGNC:CASP7))
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140 cat(p(HGNC:CASP9)) directlyIncreases cat(p(HGNC:CASP6))
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141 tscript(p(HGNC:FOXO1)) isA tscript(p(SFAM:"FOXO Family"))
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142 tscript(p(HGNC:FOXO3)) isA tscript(p(SFAM:"FOXO Family"))
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143 p(HGNC:BCL2L11) actsIn cat(p(HGNC:BCL2L11))
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144 p(HGNC:BCL2L11) increases bp(MESHPP:Apoptosis)
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145 cat(p(HGNC:FADD)) increases cat(p(HGNC:CASP10))
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146 cat(p(HGNC:FADD)) directlyIncreases cat(p(HGNC:CASP8))
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147 cat(p(HGNC:BCL2)) directlyDecreases cat(p(HGNC:BAX))
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148 cat(p(HGNC:BCL2)) decreases bp(MESHPP:Apoptosis)
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149 cat(p(HGNC:BCL2)) decreases cat(p(HGNC:BAK1))
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150 cat(p(HGNC:BCL2L11)) directlyIncreases cat(p(HGNC:BAX))
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151 cat(p(HGNC:BCL2L11)) directlyIncreases cat(p(HGNC:BAK1))
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152 cat(p(HGNC:BCL2L11)) increases bp(MESHPP:Apoptosis)
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153 kin(p(HGNC:AKT2)) directlyDecreases kin(p(HGNC:MAP3K5))
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154 p(HGNC:BAD,pmod(P,S,75)) directlyDecreases cat(p(HGNC:BAD))
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155 p(HGNC:PRKCD,pmod(P,T,505)) directlyIncreases kin(p(HGNC:PRKCD))
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156 p(HGNC:PRKCD) hasModification p(HGNC:PRKCD,pmod(P,T,505))
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157 p(HGNC:MAPK3) actsIn kin(p(HGNC:MAPK3))
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158 p(HGNC:BIRC3) decreases bp(MESHPP:Apoptosis)
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159 a(SCHEM:"Smoke, cigarette") increases p(HGNC:PPP1R15A)
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160 kin(p(HGNC:MAPK1)) directlyIncreases p(HGNC:BCL2L11,pmod(P,S,69))
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161 kin(p(HGNC:MAPK1)) decreases cat(p(HGNC:BAD))
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162 kin(p(HGNC:MAPK1)) directlyIncreases p(HGNC:CASP9,pmod(P,T,125))
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163 cat(p(HGNC:CASP2)) increases bp(MESHPP:Apoptosis)
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164 p(HGNC:GAS2) positiveCorrelation bp(MESHPP:Apoptosis)
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165 p(HGNC:GAS2) actsIn cat(p(HGNC:GAS2))
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166 p(HGNC:TNFSF10) increases cat(p(HGNC:TNFRSF10A))
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167 p(HGNC:TNFSF10) increases cat(p(HGNC:TNFRSF10B))
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168 p(HGNC:TNFSF10) increases complex(p(HGNC:RIPK1),p(HGNC:TNFRSF10A))
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169 p(HGNC:PRKCZ) hasModification p(HGNC:PRKCZ,pmod(P,T,410))
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170 p(HGNC:PRKCZ,pmod(P,T,410)) directlyIncreases kin(p(HGNC:PRKCZ))
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171 p(HGNC:CYCS) increases bp(MESHPP:Apoptosis)
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172 bp(MESHPP:Apoptosis) isA bp(GOBP:"cell death")
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173 kin(p(HGNC:EIF2AK3)) directlyIncreases p(HGNC:EIF2S1,pmod(P,S,52))
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174 cat(p(HGNC:BAX)) increases bp(MESHPP:Apoptosis)
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175 cat(p(HGNC:BAX)) increases tport(complex(GOCC:"mitochondrial permeability transition pore complex"))
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176 p(HGNC:MCL1) actsIn cat(p(HGNC:MCL1))
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177 cat(p(HGNC:TNFRSF1A)) increases cat(p(HGNC:TRADD))
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178 cat(p(HGNC:TNFRSF1A)) increases cat(p(HGNC:TRAF2))
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179 cat(p(HGNC:BCL2L1)) decreases bp(MESHPP:Apoptosis)
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180 cat(p(HGNC:BCL2L1)) directlyDecreases cat(p(HGNC:BAX))
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181 cat(p(HGNC:BCL2L1)) directlyDecreases cat(p(HGNC:BAK1))
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182 p(HGNC:EP300) actsIn tscript(p(HGNC:EP300))
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183 a(SCHEM:Leptin) decreases bp(MESHPP:Apoptosis)
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184 p(HGNC:CHUK) hasModification p(HGNC:CHUK,pmod(P,S,176))
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185 kin(p(HGNC:MAP3K14)) increases kin(complex(SCOMP:"IkappaB Kinase Complex"))
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186 kin(p(HGNC:MAP3K14)) directlyIncreases p(HGNC:CHUK,pmod(P,S,176))
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187 p(HGNC:PRKCA) hasModification p(HGNC:PRKCA,pmod(P,T,638))
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188 complex(p(HGNC:HSPA5),p(HGNC:EIF2AK3)) hasComponent p(HGNC:HSPA5)
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189 complex(p(HGNC:HSPA5),p(HGNC:EIF2AK3)) hasComponent p(HGNC:EIF2AK3)
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190 complex(p(HGNC:HSPA5),p(HGNC:EIF2AK3)) directlyDecreases kin(p(HGNC:EIF2AK3))
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191 p(HGNC:CASP2) actsIn cat(p(HGNC:CASP2))
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192 kin(p(SFAM:"PRKA Family")) decreases cat(p(HGNC:BAD))
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193 kin(p(SFAM:"PRKA Family")) directlyIncreases tscript(p(HGNC:CREB1))
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194 cat(p(HGNC:MCL1)) directlyDecreases cat(p(HGNC:BAK1))
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195 cat(p(HGNC:MCL1)) directlyDecreases cat(p(HGNC:BAX))
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196 bp(MESHPP:"DNA Fragmentation") increases bp(MESHPP:Apoptosis)
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197 kin(p(HGNC:IKBKE)) increases tscript(complex(SCOMP:"Nfkb Complex"))
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198 p(SFAM:"PRKC Family") actsIn kin(p(SFAM:"PRKC Family"))
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199 p(HGNC:PRKCA) isA p(SFAM:"PRKC Family")
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200 p(HGNC:PRKCD) isA p(SFAM:"PRKC Family")
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201 p(HGNC:PRKCE) isA p(SFAM:"PRKC Family")
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202 p(HGNC:PRKCZ) isA p(SFAM:"PRKC Family")
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203 p(SFAM:"MAPK JNK Family") actsIn kin(p(SFAM:"MAPK JNK Family"))
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204 p(HGNC:MAPK8) isA p(SFAM:"MAPK JNK Family")
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205 p(HGNC:MAPK10) isA p(SFAM:"MAPK JNK Family")
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206 p(HGNC:MAPK9) isA p(SFAM:"MAPK JNK Family")
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207 p(HGNC:PRKCA) actsIn kin(p(HGNC:PRKCA))
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208 p(HGNC:PRKCA) directlyIncreases kin(p(HGNC:RAF1))
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209 p(HGNC:CASP10) actsIn cat(p(HGNC:CASP10))
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210 p(HGNC:BIRC2) decreases bp(MESHPP:Apoptosis)
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211 complex(p(HGNC:BRCA1),p(HGNC:TP53)) hasComponent p(HGNC:TP53)
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212 complex(p(HGNC:BRCA1),p(HGNC:TP53)) increases p(HGNC:BAX)
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213 deg(p(HGNC:LMNB1)) directlyDecreases p(HGNC:LMNB1)
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214 deg(p(HGNC:LMNB1)) increases bp(MESHPP:Apoptosis)
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215 p(HGNC:BCL2L11,pmod(P,T,116)) directlyIncreases cat(p(HGNC:BCL2L11))
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216 p(SFAM:"PRKC Family") hasModification p(SFAM:"PRKC Family",pmod(P,S,660))
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217 complex(p(HGNC:BAD),p(SFAM:"14-3-3 Family")) decreases bp(MESHPP:Apoptosis)
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218 kin(p(HGNC:PDPK1)) directlyIncreases p(HGNC:PRKCZ,pmod(P,T,410))
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219 kin(p(HGNC:PDPK1)) increases kin(p(HGNC:PRKCA))
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220 kin(p(HGNC:PDPK1)) directlyIncreases kin(p(SFAM:"PRKC Family"))
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221 kin(p(HGNC:PDPK1)) directlyIncreases kin(p(HGNC:PRKCD))
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222 kin(p(HGNC:PDPK1)) directlyIncreases kin(p(HGNC:PRKCZ))
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223 bp(GOBP:"response to oxidative stress") increases p(HGNC:TNFRSF10B)
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224 bp(GOBP:"response to oxidative stress") increases p(HGNC:TNFRSF10A)
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225 bp(GOBP:"response to oxidative stress") increases p(HGNC:TNFRSF10C)
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226 p(HGNC:CASP3) increases bp(MESHPP:Apoptosis)
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227 p(HGNC:CASP3) actsIn cat(p(HGNC:CASP3))
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228 complex(SCOMP:"IkappaB Kinase Complex") actsIn kin(complex(SCOMP:"IkappaB Kinase Complex"))
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229 complex(SCOMP:"IkappaB Kinase Complex") hasComponent p(HGNC:CHUK)
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230 complex(SCOMP:"IkappaB Kinase Complex") hasComponent p(HGNC:IKBKG)
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231 complex(SCOMP:"IkappaB Kinase Complex") hasComponent p(HGNC:IKBKB)
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232 kin(p(HGNC:RIPK1)) increases kin(complex(SCOMP:"IkappaB Kinase Complex"))
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233 kin(p(HGNC:RIPK1)) directlyIncreases p(HGNC:MAP3K1,pmod(P,S,957))
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234 kin(p(HGNC:RIPK1)) directlyIncreases p(HGNC:MAP3K1,pmod(P,S,994))
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235 p(HGNC:FADD) actsIn cat(p(HGNC:FADD))
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236 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:BAX)
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237 tscript(p(HGNC:TP53)) increases p(HGNC:IGFBP3)
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238 tscript(p(HGNC:TP53)) decreases p(HGNC:BCL2)
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239 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:PTEN)
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240 tscript(p(HGNC:TP53)) directlyDecreases p(HGNC:BIRC5)
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241 tscript(p(HGNC:TP53)) increases p(HGNC:DFFA)
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242 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:BAD)
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243 tscript(p(HGNC:TP53)) decreases p(HGNC:BCL2L1)
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244 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:RPS27L)
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245 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:CASP6)
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246 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:TNFSF10)
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247 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:TP53I3)
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248 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:PERP)
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249 tscript(p(HGNC:TP53)) directlyDecreases p(HGNC:BIRC3)
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250 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:CYFIP2)
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251 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:FAS)
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252 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:APAF1)
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253 tscript(p(HGNC:TP53)) increases p(HGNC:TP53INP1)
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254 tscript(p(HGNC:TP53)) directlyDecreases p(HGNC:BIRC2)
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255 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:BBC3)
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256 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:TNFRSF10C)
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257 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:PMAIP1)
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258 tscript(p(HGNC:TP53)) directlyIncreases p(EGID:55367)
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259 tscript(p(HGNC:TP53)) increases p(HGNC:TNFRSF1A)
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260 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:TNFRSF10A)
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261 tscript(p(HGNC:TP53)) increases p(HGNC:CASP8)
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262 tscript(p(HGNC:TP53)) increases p(HGNC:TNFRSF1B)
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263 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:TNFRSF10D)
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264 tscript(p(HGNC:TP53)) increases p(HGNC:RNF144B)
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265 tscript(p(HGNC:TP53)) decreases p(HGNC:XIAP)
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266 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:TNFRSF10B)
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267 tscript(p(HGNC:TP53)) increases p(HGNC:FASLG)
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268 tscript(p(HGNC:TP53)) directlyIncreases p(HGNC:BAK1)
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269 tscript(p(HGNC:TP53)) increases p(HGNC:BIK)
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270 p(HGNC:BCL2A1) decreases bp(MESHPP:Apoptosis)
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271 p(HGNC:CASP8) actsIn cat(p(HGNC:CASP8))
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272 p(HGNC:TNFRSF1A) actsIn cat(p(HGNC:TNFRSF1A))
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273 kin(complex(SCOMP:"IkappaB Kinase Complex")) directlyIncreases p(HGNC:NFKBIA,pmod(P,S,32))
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274 kin(complex(SCOMP:"IkappaB Kinase Complex")) directlyIncreases p(HGNC:NFKBIA,pmod(P,S,36))
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275 p(HGNC:PTEN,pmod(P,T,382)) directlyDecreases phos(p(HGNC:PTEN))
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276 p(HGNC:RAC1,pmod(P,S,71)) directlyDecreases gtp(p(HGNC:RAC1))
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277 cat(p(HGNC:CASP6)) directlyIncreases deg(p(HGNC:LMNA))
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278 p(HGNC:CREB1) actsIn tscript(p(HGNC:CREB1))
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279 p(HGNC:BIRC5) decreases bp(MESHPP:Apoptosis)
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280 p(HGNC:BIRC5) directlyDecreases cat(p(HGNC:CASP3))
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281 p(HGNC:MAP3K1,pmod(P,S,957)) directlyIncreases kin(p(HGNC:MAP3K1))
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282 p(HGNC:BAK1) actsIn cat(p(HGNC:BAK1))
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283 p(HGNC:BID) actsIn cat(p(HGNC:BID))
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284 p(HGNC:BAD,pmod(P,S,99)) directlyDecreases cat(p(HGNC:BAD))
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285 p(HGNC:BAD,pmod(P,S,99)) increases complex(p(HGNC:BAD),p(SFAM:"14-3-3 Family"))
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286 kin(p(HGNC:RPS6KA1)) directlyIncreases p(HGNC:CREB1,pmod(P,S,133))
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287 kin(p(HGNC:RPS6KA1)) decreases cat(p(HGNC:BAD))
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288 kin(p(HGNC:RPS6KA1)) directlyIncreases p(HGNC:BAD,pmod(P,S,75))
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289 deg(p(HGNC:LMNA)) directlyDecreases p(HGNC:LMNA)
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290 deg(p(HGNC:LMNA)) increases bp(MESHPP:Apoptosis)
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291 p(HGNC:IKBKE) actsIn kin(p(HGNC:IKBKE))
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292 p(HGNC:CASP4) actsIn cat(p(HGNC:CASP4))
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293 p(HGNC:TLR4) decreases p(HGNC:CASP3)
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294 kin(p(HGNC:MAP3K7)) directlyIncreases kin(complex(SCOMP:"IkappaB Kinase Complex"))
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295 p(HGNC:BCL2) decreases bp(MESHPP:Apoptosis)
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296 p(HGNC:BCL2) actsIn cat(p(HGNC:BCL2))
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297 p(HGNC:ELK1,pmod(P,S,383)) directlyIncreases tscript(p(HGNC:ELK1))
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298 cat(p(HGNC:CASP8)) increases cat(p(HGNC:BID))
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299 cat(p(HGNC:CASP8)) directlyIncreases cat(p(HGNC:CASP3))
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300 p(HGNC:CHUK) actsIn kin(p(HGNC:CHUK))
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301 p(HGNC:BAX) increases bp(MESHPP:Apoptosis)
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302 p(HGNC:BAX) actsIn cat(p(HGNC:BAX))
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303 p(HGNC:IKBKB) hasModification p(HGNC:IKBKB,pmod(P,S,181))
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304 tscript(p(HGNC:CREB1)) increases p(HGNC:BCL2)
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305 p(HGNC:PTEN,pmod(P,S,380)) directlyDecreases phos(p(HGNC:PTEN))
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306 tscript(p(HGNC:FOXO3)) directlyIncreases p(HGNC:BCL2L11)
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307 kin(p(HGNC:MAP3K1)) increases kin(p(HGNC:IKBKB))
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308 p(HGNC:CASP9,pmod(P,T,125)) directlyDecreases cat(p(HGNC:CASP9))
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309 kin(p(HGNC:PRKCZ)) directlyDecreases kin(p(SFAM:"AKT Family"))
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310 p(HGNC:TNFRSF1B) actsIn cat(p(HGNC:TNFRSF1B))
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311 tscript(p(HGNC:ATF4)) directlyIncreases p(HGNC:DDIT3)
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312 kin(p(HGNC:BMX)) increases bp(MESHPP:Apoptosis)
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313 p(HGNC:PRKD1,pmod(P,S,742)) directlyIncreases kin(p(HGNC:PRKD1))
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314 tscript(p(HGNC:EP300)) directlyIncreases tscript(p(HGNC:CREB1))
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315 p(HGNC:PAK2) actsIn kin(p(HGNC:PAK2))
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316 p(HGNC:PMAIP1) actsIn cat(p(HGNC:PMAIP1))
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317 p(HGNC:PRKD1,pmod(P,S,738)) directlyIncreases kin(p(HGNC:PRKD1))
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318 p(HGNC:RAF1,pmod(P,S,259)) directlyDecreases kin(p(HGNC:RAF1))
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319 p(HGNC:TNF) directlyIncreases cat(p(HGNC:TNFRSF1A))
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320 p(HGNC:TNF) increases p(HGNC:TNFRSF10A)
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321 p(HGNC:TNF) increases p(HGNC:TNFRSF10B)
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322 p(HGNC:TNF) directlyIncreases cat(p(HGNC:TNFRSF1B))
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323 p(HGNC:TNF) increases p(HGNC:TNFRSF10C)
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324 p(HGNC:BCL2L1) actsIn cat(p(HGNC:BCL2L1))
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325 p(HGNC:BCL2L1) decreases bp(MESHPP:Apoptosis)
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326 p(HGNC:NFKBIE) directlyDecreases tscript(complex(SCOMP:"Nfkb Complex"))
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327 p(HGNC:RIPK1) actsIn kin(p(HGNC:RIPK1))
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328 p(HGNC:AKT1,pmod(P,T,308)) directlyIncreases kin(p(HGNC:AKT1))
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329 p(HGNC:TNFRSF10A) actsIn cat(p(HGNC:TNFRSF10A))
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330 p(HGNC:TNFRSF10A) increases bp(MESHPP:Apoptosis)
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331 p(HGNC:MAP3K1) actsIn kin(p(HGNC:MAP3K1))
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332 cat(p(HGNC:TRADD)) increases cat(p(HGNC:CASP8))
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333 p(HGNC:PARP1) decreases bp(MESHPP:Apoptosis)
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334 kin(p(SFAM:"AKT Family")) directlyIncreases p(HGNC:BAX,pmod(P,S,184))
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335 kin(p(HGNC:AKT2)) isA kin(p(SFAM:"AKT Family"))
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336 kin(p(SFAM:"AKT Family")) directlyIncreases p(HGNC:RAF1,pmod(P,S,259))
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337 kin(p(SFAM:"AKT Family")) directlyIncreases p(HGNC:BAD,pmod(P,S,99))
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338 kin(p(HGNC:AKT3)) isA kin(p(SFAM:"AKT Family"))
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339 kin(p(SFAM:"AKT Family")) directlyIncreases p(HGNC:RAC1,pmod(P,S,71))
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340 kin(p(SFAM:"AKT Family")) directlyIncreases p(HGNC:MAP3K5,pmod(P,S,83))
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341 kin(p(SFAM:"AKT Family")) directlyDecreases tscript(p(SFAM:"FOXO Family"))
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342 kin(p(SFAM:"AKT Family")) directlyIncreases p(HGNC:FOXO1,pmod(P,S,256))
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343 kin(p(HGNC:AKT1)) isA kin(p(SFAM:"AKT Family"))
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344 kin(p(SFAM:"AKT Family")) directlyIncreases p(HGNC:BAD,pmod(P,S,75))
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345 p(HGNC:BAD) actsIn cat(p(HGNC:BAD))
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346 cat(p(HGNC:FAS)) directlyIncreases cat(p(HGNC:FADD))
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347 kin(p(HGNC:MAP3K5)) increases bp(MESHPP:Apoptosis)
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348 kin(p(HGNC:MAP3K5)) directlyIncreases kin(p(HGNC:MAP2K7))
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349 tscript(p(HGNC:FOXO1)) directlyIncreases p(HGNC:BCL2L11)
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350 complex(p(HGNC:HSPA5),p(HGNC:ERN1)) hasComponent p(HGNC:ERN1)
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351 complex(p(HGNC:HSPA5),p(HGNC:ERN1)) hasComponent p(HGNC:HSPA5)
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352 complex(p(HGNC:HSPA5),p(HGNC:ERN1)) directlyDecreases cat(p(HGNC:ERN1))
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353 phos(p(HGNC:PTEN)) decreases kin(p(SFAM:"PIK3C Class IA Family"))
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354 p(HGNC:XBP1) actsIn tscript(p(HGNC:XBP1))
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355 p(HGNC:AKT1,pmod(P,S,473)) directlyIncreases kin(p(HGNC:AKT1))
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356 p(HGNC:CFLAR) decreases bp(MESHPP:Apoptosis)
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357 p(HGNC:CFLAR) decreases cat(p(HGNC:CASP8))
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358 kin(p(HGNC:RAF1)) increases tscript(p(HGNC:ELK1))
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359 kin(p(HGNC:MAPK8)) isA kin(p(SFAM:"MAPK JNK Family"))
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360 kin(p(SFAM:"MAPK JNK Family")) directlyIncreases p(HGNC:BCL2L11,pmod(P,T,116))
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361 kin(p(HGNC:MAPK10)) isA kin(p(SFAM:"MAPK JNK Family"))
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362 kin(p(SFAM:"MAPK JNK Family")) increases cat(p(HGNC:BAX))
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363 kin(p(HGNC:MAPK9)) isA kin(p(SFAM:"MAPK JNK Family"))
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364 p(HGNC:BCL2L11,pmod(P,S,69)) decreases cat(p(HGNC:BCL2L11))
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365 p(HGNC:DFFB) actsIn cat(p(HGNC:DFFB))
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366 p(HGNC:CHUK) hasModification p(HGNC:CHUK,pmod(P,S,180))
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367 cat(p(HGNC:BID)) directlyIncreases cat(p(HGNC:BAX))
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368 cat(p(HGNC:BID)) directlyIncreases cat(p(HGNC:BAK1))
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369 cat(p(HGNC:BID)) increases bp(MESHPP:Apoptosis)
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370 deg(p(HGNC:LMNB2)) directlyDecreases p(HGNC:LMNB2)
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371 deg(p(HGNC:LMNB2)) increases bp(MESHPP:Apoptosis)
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372 p(HGNC:FASLG) directlyIncreases cat(p(HGNC:FAS))
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373 p(SFAM:"AKT Family") actsIn kin(p(SFAM:"AKT Family"))
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374 p(HGNC:AKT3) isA p(SFAM:"AKT Family")
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375 p(HGNC:AKT1) isA p(SFAM:"AKT Family")
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376 p(HGNC:AKT2) isA p(SFAM:"AKT Family")
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377 p(HGNC:MAP3K5,pmod(P,S,83)) directlyDecreases kin(p(HGNC:MAP3K5))
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378 cat(p(HGNC:DFFB)) increases bp(MESHPP:"DNA Fragmentation")
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379 p(HGNC:DDIT3) actsIn tscript(p(HGNC:DDIT3))
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380 p(HGNC:DDIT3) increases p(HGNC:BBC3)
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381 p(HGNC:DDIT3) increases p(HGNC:BAX)
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382 p(HGNC:DDIT3) increases p(HGNC:BCL2L11)
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383 p(HGNC:FOXO1) actsIn tscript(p(HGNC:FOXO1))
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384 cat(p(HGNC:PMAIP1)) increases cat(p(HGNC:BAK1))
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385 cat(p(HGNC:PMAIP1)) increases cat(p(HGNC:BAX))
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386 p(HGNC:CASP6) actsIn cat(p(HGNC:CASP6))
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387 kin(p(HGNC:MAP2K7)) directlyIncreases kin(p(SFAM:"MAPK JNK Family"))
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388 cat(p(HGNC:XIAP)) decreases cat(p(HGNC:CASP3))
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389 cat(p(HGNC:XIAP)) decreases cat(p(HGNC:CASP9))
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390 cat(p(HGNC:XIAP)) decreases cat(p(HGNC:CASP7))
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391 gtp(p(HGNC:RAC1)) increases kin(p(SFAM:"MAPK JNK Family"))
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392 gtp(p(HGNC:RAC1)) increases kin(p(HGNC:MAPK10))
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393 gtp(p(HGNC:RAC1)) directlyIncreases kin(p(HGNC:MAPK8))
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394 a(SCHEM:"Phosphatidylinositol-3,4,5-trisphosphate") directlyIncreases kin(p(HGNC:PDPK1))
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395 cat(p(HGNC:CASP4)) increases bp(MESHPP:Apoptosis)
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396 cat(p(HGNC:ACIN1)) increases bp(MESHPP:Apoptosis)
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397 p(HGNC:ELK1) actsIn tscript(p(HGNC:ELK1))
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398 p(HGNC:PRKCE) actsIn kin(p(HGNC:PRKCE))
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399 p(HGNC:ROCK1) actsIn kin(p(HGNC:ROCK1))
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400 a(SCHEM:Calcium) increases kin(p(HGNC:PRKCA))
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401 a(SCHEM:Calcium) increases kin(p(HGNC:PRKCD))
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402 a(SCHEM:Calcium) directlyIncreases kin(p(SFAM:"PRKC Family"))
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403 a(SCHEM:Calcium) increases kin(p(HGNC:PRKCE))
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404 kin(p(HGNC:NFKBIA)) decreases tscript(complex(SCOMP:"Nfkb Complex"))
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405 kin(p(HGNC:PRKD1)) directlyIncreases kin(p(HGNC:MAP3K5))
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406 p(HGNC:TRADD) actsIn cat(p(HGNC:TRADD))
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407 p(HGNC:BBC3) actsIn cat(p(HGNC:BBC3))
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408 p(HGNC:BBC3) increases bp(MESHPP:Apoptosis)
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409 kin(p(HGNC:RPS6KA1)) isA kin(p(SFAM:"RPS6KA Family"))
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410 cat(p(HGNC:TNFRSF10A)) increases cat(p(HGNC:TRAF2))
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411 cat(p(HGNC:DFFA)) decreases cat(p(HGNC:DFFB))
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412 p(SFAM:"RPS6KA Family") actsIn kin(p(SFAM:"RPS6KA Family"))
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413 cat(p(HGNC:HTRA2)) directlyDecreases cat(p(HGNC:XIAP))
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414 p(HGNC:MAP3K7) actsIn kin(p(HGNC:MAP3K7))
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415 p(HGNC:MARCKS) hasModification p(HGNC:MARCKS,pmod(P,S,159))
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416 p(HGNC:CREB1,pmod(P,S,133)) directlyIncreases tscript(p(HGNC:CREB1))
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417 p(HGNC:EIF2S1,pmod(P,S,52)) increases p(HGNC:ATF4)
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418 p(HGNC:EIF2S1) hasModification p(HGNC:EIF2S1,pmod(P,S,52))
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419 p(HGNC:NFKBIA,pmod(P,S,32)) directlyIncreases deg(p(HGNC:NFKBIA))
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420 p(HGNC:CASP7) actsIn cat(p(HGNC:CASP7))
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421 deg(p(HGNC:NFKBIA)) directlyDecreases p(HGNC:NFKBIA)
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422 p(HGNC:PDPK1,pmod(P,S,241)) increases p(HGNC:PDPK1)
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423 p(HGNC:CXCL12) increases gtp(p(HGNC:RAC1))
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424 p(CXCL12) increases gtp(p(HGNC:RAC1))
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425 bp(MESHPP:Apoptosis) positiveCorrelation p(HGNC:TLR4)
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426 bp(MESHPP:Apoptosis) negativeCorrelation p(HGNC:GSTP1)
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427 p(HGNC:MAP1LC3B) increases bp(MESHPP:Apoptosis)
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428 p(HGNC:KDR) decreases bp(MESHPP:Apoptosis)
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429 p(HGNC:KDR) decreases path(MESHD:Emphysema)
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430 bp(MESHPP:"DNA Methylation") association path(MESHD:"Pulmonary Disease, Chronic Obstructive")
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431 bp(MESHPP:"DNA Methylation") association bp(MESHPP:Apoptosis)
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432 path(MESHD:"Pulmonary Disease, Chronic Obstructive") increases bp(MESHPP:Apoptosis)
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433 p(HGNC:PTGS2) association a(SCHEM:"Smoke, cigarette")
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434 p(HGNC:PTGS2) negativeCorrelation bp(MESHPP:Apoptosis)
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435 a(SCHEM:"Smoke, cigarette") increases p(HGNC:HSPA5)
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436 p(HGNC:HSPA5) decreases p(HGNC:CASP3)
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437 p(HGNC:SCGB1A1) decreases bp(MESHPP:Apoptosis)
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438 p(HGNC:EIF2AK3) decreases bp(MESHPP:Apoptosis)
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439 p(HGNC:FLOT2) decreases p(HGNC:DIABLO)
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440 p(HGNC:PGF) increases bp(MESHPP:Apoptosis)
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441 kin(p(SFAM:"MAPK JNK Family")) increases bp(MESHPP:Apoptosis)
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442 kin(p(SFAM:"PRKC Family")) increases bp(MESHPP:Apoptosis)
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443 p(HGNC:BACH2) increases kin(p(SFAM:"MAPK JNK Family"))
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444 cat(p(HGNC:TRADD)) increases cat(p(HGNC:FADD))
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