changeset 0:69795939c29b draft

Uploaded
author cpt
date Fri, 10 Jun 2022 08:41:20 +0000
parents
children bd1901839519
files cpt_progressivemauve/cpt-macros.xml cpt_progressivemauve/macros.xml cpt_progressivemauve/progressivemauve.xml cpt_progressivemauve/test-data/1.gff3 cpt_progressivemauve/test-data/1.mums cpt_progressivemauve/test-data/1.nhx cpt_progressivemauve/test-data/1.xmfa cpt_progressivemauve/test-data/2.xmfa cpt_progressivemauve/test-data/3.nhx cpt_progressivemauve/test-data/3.xmfa cpt_progressivemauve/test-data/4.mums cpt_progressivemauve/test-data/4.xmfa cpt_progressivemauve/test-data/5.xmfa cpt_progressivemauve/test-data/karma.fa cpt_progressivemauve/test-data/merged.fa cpt_progressivemauve/test-data/phagey.fa
diffstat 16 files changed, 46338 insertions(+), 0 deletions(-) [+]
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--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/cpt-macros.xml	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,115 @@
+<?xml version="1.0"?>
+<macros>
+	<xml name="gff_requirements">
+		<requirements>
+			<requirement type="package" version="2.7">python</requirement>
+			<requirement type="package" version="1.65">biopython</requirement>
+			<requirement type="package" version="2.12.1">requests</requirement>
+			<yield/>
+		</requirements>
+		<version_command>
+		<![CDATA[
+			cd $__tool_directory__ && git rev-parse HEAD
+		]]>
+		</version_command>
+	</xml>
+	<xml name="citation/mijalisrasche">
+		<citation type="doi">10.1371/journal.pcbi.1008214</citation>
+		<citation type="bibtex">@unpublished{galaxyTools,
+		author = {E. Mijalis, H. Rasche},
+		title = {CPT Galaxy Tools},
+		year = {2013-2017},
+		note = {https://github.com/tamu-cpt/galaxy-tools/}
+		}
+		</citation>
+	</xml>
+	<xml name="citations">
+		<citations>
+			<citation type="doi">10.1371/journal.pcbi.1008214</citation>
+			<citation type="bibtex">
+			@unpublished{galaxyTools,
+				author = {E. Mijalis, H. Rasche},
+				title = {CPT Galaxy Tools},
+				year = {2013-2017},
+				note = {https://github.com/tamu-cpt/galaxy-tools/}
+			}
+			</citation> 
+		<yield/>
+		</citations>
+	</xml>
+    	<xml name="citations-crr">
+		<citations>
+			<citation type="doi">10.1371/journal.pcbi.1008214</citation>
+			<citation type="bibtex">
+			@unpublished{galaxyTools,
+				author = {C. Ross},
+				title = {CPT Galaxy Tools},
+				year = {2020-},
+				note = {https://github.com/tamu-cpt/galaxy-tools/}
+			}
+			</citation>
+		<yield/>
+		</citations>
+	</xml>
+        <xml name="citations-2020">
+		<citations>
+			<citation type="doi">10.1371/journal.pcbi.1008214</citation>
+			<citation type="bibtex">
+			@unpublished{galaxyTools,
+				author = {E. Mijalis, H. Rasche},
+				title = {CPT Galaxy Tools},
+				year = {2013-2017},
+				note = {https://github.com/tamu-cpt/galaxy-tools/}
+			}
+			</citation>
+                        <citation type="bibtex">
+			@unpublished{galaxyTools,
+				author = {A. Criscione},
+				title = {CPT Galaxy Tools},
+				year = {2019-2021},
+				note = {https://github.com/tamu-cpt/galaxy-tools/}
+			}
+                        </citation>
+                        <yield/>
+		</citations>
+	</xml>
+        <xml name="citations-2020-AJC-solo">
+		<citations>
+			<citation type="doi">10.1371/journal.pcbi.1008214</citation>
+                        <citation type="bibtex">
+			@unpublished{galaxyTools,
+				author = {A. Criscione},
+				title = {CPT Galaxy Tools},
+				year = {2019-2021},
+				note = {https://github.com/tamu-cpt/galaxy-tools/}
+			}
+                        </citation>
+                        <yield/>
+		</citations>
+	</xml>
+        <xml name="citations-clm">
+		<citations>
+			<citation type="doi">10.1371/journal.pcbi.1008214</citation>
+			<citation type="bibtex">
+			@unpublished{galaxyTools,
+				author = {C. Maughmer},
+				title = {CPT Galaxy Tools},
+				year = {2017-2020},
+				note = {https://github.com/tamu-cpt/galaxy-tools/}
+			}
+			</citation>
+                        <yield/>
+		</citations>
+	</xml>
+        <xml name="sl-citations-clm">
+			<citation type="bibtex">
+			@unpublished{galaxyTools,
+				author = {C. Maughmer},
+				title = {CPT Galaxy Tools},
+				year = {2017-2020},
+				note = {https://github.com/tamu-cpt/galaxy-tools/}
+			}
+			</citation>
+                        <yield/>
+	</xml>
+</macros>
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/macros.xml	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,58 @@
+<?xml version="1.0"?>
+<macros>
+	<xml name="requirements">
+		<requirements>
+			<requirement type="package">progressivemauve</requirement>
+			<requirement type="package" version="3.8.13">python</requirement>
+			<requirement type="package" version="1.79">biopython</requirement>
+			<requirement type="package" version="1.2.2">cpt_gffparser</requirement>  
+			<yield/>
+		</requirements>
+	</xml>
+	<token name="@WRAPPER_VERSION@">2.4.0</token>
+	<xml name="citation/progressive_mauve">
+		<citation type="doi">10.1371/journal.pone.0011147</citation>
+	</xml>
+	<xml name="citation/gepard">
+		<citation type="doi">10.1093/bioinformatics/btm039</citation>
+	</xml>
+
+	<token name="@XMFA_INPUT@">
+		"$xmfa"
+	</token>
+	<xml name="xmfa_input"
+		token_formats="xmfa">
+		<param type="data" format="@FORMATS@" name="xmfa" label="XMFA MSA" />
+	</xml>
+
+	<token name="@XMFA_FA_INPUT@">
+		"$sequences"
+	</token>
+	<xml name="xmfa_fa_input">
+		<param type="data" format="fasta" name="sequences" label="Sequences in alignment"
+			help="These sequences should be the SAME DATASET that was used in the progressiveMauve run. Failing that, they should be provided in the same order as in original progressiveMauve run"/>
+
+	</xml>
+	<xml name="genome_selector">
+	    <param name="genome_fasta" type="data" format="fasta" label="Source FASTA Sequence"/>
+	</xml>
+	<xml name="gff3_input">
+		<param label="GFF3 Annotations" name="gff3_data" type="data" format="gff3"/>
+	</xml>
+	<xml name="input/gff3+fasta">
+		<expand macro="gff3_input" />
+		<expand macro="genome_selector" />
+	</xml>
+	<token name="@INPUT_GFF@">
+	"$gff3_data"
+	</token>
+	<token name="@INPUT_FASTA@">
+		genomeref.fa
+	</token>
+	<token name="@GENOME_SELECTOR_PRE@">
+		ln -s $genome_fasta genomeref.fa;
+	</token>
+	<token name="@GENOME_SELECTOR@">
+		genomeref.fa
+	</token>
+</macros>
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/progressivemauve.xml	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,315 @@
+<?xml version="1.0"?>
+<tool id="progressivemauve" name="progressiveMauve" version="19.1.0.0" profile="16.04">
+  <description>constructs multiple genome alignments</description>
+  <macros>
+    <import>macros.xml</import>
+		<import>cpt-macros.xml</import>
+  </macros>
+  <requirements>
+    <requirement type="package">progressivemauve</requirement>
+  </requirements>
+  <command detect_errors="aggressive"><![CDATA[
+## Symlink files in with correct extensions
+#for $file in $sequences:
+    ln -s $file `basename $file`;
+#end for
+
+progressiveMauve
+## Input Options
+
+#if $apply_backbone:
+    --apply-backbone=$apply_backbone
+#end if
+--island-gap-size=$island_gap_size
+$mums
+
+#if $seed_weight:
+    --seed-weight=$seed_weight
+#end if
+
+#if $max_gapped_aligner_length:
+    --max-gapped-aligner-length=$max_gapped_aligner_length
+#end if
+
+#if $match_input:
+    --match-input=$match_input
+#end if
+
+$collinear
+--scoring-scheme=$scoring_scheme
+$no_weight_scaling
+
+--max-breakpoint-distance-scale=$max_breakpoint_distance_scale
+--conservation-distance-scale=$conservation_distance_scale
+$skip_refinement
+$skip_gapped_alignment
+
+#if $bp_dist_estimate_min_score:
+    --bp-dist-estimate-min-score=$bp_dist_estimate_min_score
+#end if
+
+#if $gap_open:
+    --gap-open=$gap_open
+#end if
+
+#if $gap_extend:
+    --gap-extend=$gap_extend
+#end if
+
+#if $weight:
+    --weight=$weight
+#end if
+
+#if $min_scaled_penalty:
+    --min-scaled-penalty=$min_scaled_penalty
+#end if
+
+--hmm-p-go-homologous=$hmm_p_go_homologous
+--hmm-p-go-unrelated=$hmm_p_go_unrelated
+--hmm-identity=$hmm_identity
+
+$seed_family
+$solid_seeds
+$coding_seeds
+$no_recursion
+$disable_backbone
+
+## Outputs
+--output=$output
+#if $output_guide_tree:
+    --output-guide-tree=$output_guide_tree_file
+#end if
+
+#if $output_backbone:
+    --backbone-output=$output_backbone_file
+#end if
+
+## Sequences
+#for file in $sequences:
+    `basename "${file}"`
+#end for
+
+]]></command>
+  <inputs>
+      <param type="data" format="fasta" name="sequences" multiple="True"
+          label="Select sequences to align" help="in fasta format" />
+      <param type="data" format="xmfa" label="Apply Backbone" name="apply_backbone" optional="True"
+          help="Read an existing sequence alignment in XMFA format and apply backbone statistics to it (--apply-backbone)" />
+
+      <param type="integer" label="Island gap size" value="20" name="island_gap_size"
+          help="Alignment gaps above this size in nucleotides are considered to be islands (--island-gap-size)"/>
+
+      <param type="boolean" truevalue="--disable-backbone" falsevalue="" name="disable_backbone"
+          label="Disable backbone" help="Disable backbone detection (--disable-backbone)" />
+
+      <param type="boolean" truevalue="True" falsevalue="" name="output_guide_tree"
+          label="Output Guide Tree" help="Write out the guide tree used for alignment to a file (--output-guide-tree)" />
+
+      <param type="boolean" truevalue="True" falsevalue="" name="output_backbone"
+          label="Output Backbone" help="Write out the backbone to a file (--backbone-output)" />
+
+      <param type="boolean" truevalue="--mums" falsevalue="" label="MUMs" name="mums"
+          help="Find MUMs only, do not attempt to determine locally collinear blocks (LCBs) (--mums)" />
+
+      <param type="integer" label="Seed weight" name="seed_weight" value="0" optional="True"
+          help="Use the specified seed weight for calculating initial anchors (--seed-weight)" />
+
+      <param type="data" format="tabular" label="Match Input" name="match_input" optional="True"
+          help="Use specified match file instead of searching for matches (--match-input)" />
+
+    <!--<param type="file" label="input-id-matrix" help="An identity matrix describing similarity among all pairs of input sequences/alignments (- -input-id-matrix)" />-->
+    <param type="integer" label="Max gapped aligner length" value="0" optional="True" name="max_gapped_aligner_length"
+        help="Maximum number of base pairs to attempt aligning with the gapped aligner (--max-gapped-aligner-length)" />
+
+    <param type="data" format="nhx" label="input-guide-tree" optional="True" name="input_guide_tree"
+        help="A phylogenetic guide tree in Newick format that describes the order in which sequences will be aligned (--input-guide-tree)" />
+
+    <param type="boolean" truevalue="--collinear" falsevalue="" label="Collinear inputs" name="collinear"
+        help="Assume that input sequences are collinear--they have no rearrangements (--collinear)" />
+
+    <param type="select" label="Scoring scheme" name="scoring_scheme" help="Selects the anchoring score function. (--scoring-scheme)" >
+        <option value="sp" selected="True">Extant sum-of-pairs (sp)</option>
+        <option value="ancestral_sp">Sum-of-pairs + Ancestral (ancestral_sp)</option>
+        <option value="ancestral">Ancestral (ancestral)</option>
+    </param>
+
+    <param type="boolean" truevalue="--no-weight-scaling" falsevalue="" label="No weight scaling" name="no_weight_scaling"
+        help="Don't scale LCB weights by conservation distance and breakpoint distance (--no-weight-scaling)" />
+
+    <param type="float" min="0" max="1" label="max-breakpoint-distance-scale" value="0.5" name="max_breakpoint_distance_scale"
+        help="Set the maximum weight scaling by breakpoint distance. (--max-breakpoint-distance-scale)" />
+
+    <param type="float" min="0" max="1"  label="conservation-distance-scale" value="0.5" name="conservation_distance_scale"
+        help="Scale conservation distances by this amount. (--conservation-distance-scale)" />
+
+    <param type="boolean" truevalue="--skip-refinement" falsevalue="" label="Skip refinement" name="skip_refinement"
+        help="Do not perform iterative refinement (--skip-refinement)" />
+    <param type="boolean" truevalue="--skip-gapped-alignment" falsevalue="" label="Skip gapped alignment" name="skip_gapped_alignment"
+        help="Do not perform gapped alignment (--skip-gapped-alignment)" />
+    <param type="integer" label="BP dist estimate min score" name="bp_dist_estimate_min_score" value="0" optional="True"
+        help="Minimum LCB score for estimating pairwise breakpoint distance (--bp-dist-estimate-min-score)" />
+
+    <param type="integer" label="Gap open" name="gap_open" value="0" optional="True"
+        help="Gap open penalty (--gap-open)" />
+
+    <param type="select" label="Repeat penalty" name="repeat_penalty"
+        help="Sets whether the repeat scores go negative or go to zero for highly repetitive sequences. (--repeat-penalty)">
+        <option value="negative" selected="True">Negative</option>
+        <option value="zero">Zero</option>
+    </param>
+
+    <param type="integer" label="Gap extend" name="gap_extend" value="0" optional="True"
+        help="Gap extend penalty (--gap-extend)" />
+
+    <!--<param type="data" label="Substitution matrix" -->
+        <!--help="Nucleotide substitution matrix in NCBI format (- -substitution-matrix)" />-->
+
+    <param type="integer" label="Weight" name="weight" value="0" optional="True"
+        help="Minimum pairwise LCB score (--weight)" />
+    <param type="integer" label="Min scaled penalty" name="min_scaled_penalty" value="0" optional="True"
+        help="Minimum breakpoint penalty after scaling the penalty by expected divergence (--min-scaled-penalty)" />
+
+    <param type="float" label="HMM p go homologous" name="hmm_p_go_homologous" min="0" max="1" value="0.00001"
+        help="Probability of transitioning from the unrelated to the homologous state (--hmm-p-go-homologous)" />
+    <param type="float" label="HMM p go unrelated" name="hmm_p_go_unrelated" min="0" max="1" value="0.000000001"
+        help="Probability of transitioning from the homologous to the unrelated state (--hmm-p-go-unrelated)" />
+    <param type="float" label="HMM identity" name="hmm_identity" min="0" max="1" value="0.7"
+        help="Expected level of sequence identity among pairs of sequences(--hmm-identity)" />
+
+    <param type="boolean" truevalue="--seed-family" falsevalue="" label="Seed family" name="seed_family"
+        help="Use a family of spaced seeds to improve sensitivity (--seed-family)" />
+    <param type="boolean" truevalue="--solid-seeds" falsevalue="" label="Solid seeds" name="solid_seeds"
+        help="Use solid seeds. Do not permit substitutions in anchor matches. (--solid-seeds)" />
+    <param type="boolean" truevalue="--coding-seeds" falsevalue="" label="Coding seeds" name="coding_seeds"
+        help="Use coding pattern seeds. Useful to generate matches coding regions with 3rd codon position degeneracy. (--coding-seeds)" />
+    <param type="boolean" truevalue="--no-recursion" falsevalue="" label="No recursion" name="no_recursion"
+        help="Disable recursive anchor search (--no-recursion)" />
+  </inputs>
+  <outputs>
+    <data format="xmfa" name="output" label="${tool.name} alignment of ${on_string}">
+       <change_format>
+           <when input="mums" value="--mums" format="tabular" />
+       </change_format>
+    </data>
+    <data format="nhx" name="output_guide_tree_file" label="${tool.name} alignment of ${on_string}: Guide tree">
+        <filter>output_guide_tree</filter>
+    </data>
+    <data format="tabular" name="output_backbone_file" label="${tool.name} alignment of ${on_string}: Backbone">
+        <filter>output_backbone</filter>
+    </data>
+  </outputs>
+  <tests>
+      <test>
+          <param name="sequences" value="phagey.fa,karma.fa" />
+          <output name="output" file="1.xmfa" lines_diff="20"/>
+      </test>
+      <test>
+          <param name="sequences" value="merged.fa" />
+          <output name="output" file="2.xmfa" lines_diff="20"/>
+      </test>
+      <test>
+          <param name="sequences" value="merged.fa" />
+          <param name="output_guide_tree" value="True" />
+          <output name="output" file="3.xmfa" lines_diff="20"/>
+          <output name="output_guide_tree_file" file="3.nhx" />
+      </test>
+      <test>
+          <param name="sequences" value="merged.fa" />
+          <param name="mums" value="True" />
+          <output name="output" file="4.mums" compare="sim_size" delta="1000"/>
+      </test>
+      <test>
+          <param name="sequences" value="merged.fa" />
+          <param name="match_input" value="4.mums" />
+          <output name="output" file="5.xmfa" lines_diff="24"/>
+      </test>
+  </tests>
+  <help><![CDATA[
+What it does
+============
+
+Mauve is a system for efficiently constructing multiple genome alignments in
+the presence of large-scale evolutionary events such as rearrangement and
+inversion. Multiple genome alignment provides a basis for research into
+comparative genomics and the study of evolutionary dynamics. Aligning whole
+genomes is a fundamentally different problem than aligning short sequences.
+
+Mauve has been developed with the idea that a multiple genome aligner should
+require only modest computational resources. It employs algorithmic techniques
+that scale well in the amount of sequence being aligned. For example, a pair of
+Y. pestis genomes can be aligned in under a minute, while a group of 9
+divergent Enterobacterial genomes can be aligned in a few hours.
+
+
+Example Usage
+=============
+
++-----------------------------------+-------------+
+| Usage                             | Notes       |
++===================================+=============+
+| Align genomes                     |Simply       |
+|                                   |select as    |
+|                                   |many fasta   |
+|                                   |files with   |
+|                                   |one or more  |
+|                                   |sequences as |
+|                                   |necessary    |
++-----------------------------------+-------------+
+| Align genomes but also save       |Use the      |
+| the guide tree and produce a      |**Output     |
+| backbone file                     |Guide Tree** |
+|                                   |and **Output |
+|                                   |Backbone**   |
+|                                   |options      |
++-----------------------------------+-------------+
+| Align genomes, but do not         |Use the      |
+| detect forced alignment of        |**Disable    |
+| unrelated sequences               |backbone**   |
+|                                   |option       |
++-----------------------------------+-------------+
+| Detect forced alignment of        |Use the      |
+| unrelated sequence in the         |**Apply      |
+| alignment produced                |Backbone**   |
+| in previous example, use          |option and   |
+| custom Homology HMM transition    |specify the  |
+| parameters.                       |XMFA file    |
+|                                   |produced     |
+|                                   |in the       |
+|                                   |previous     |
+|                                   |example      |
++-----------------------------------+-------------+
+| Compute ungapped                  |Use the      |
+| local-multiple alignments among   |**MUMs**     |
+| the input sequences               |option       |
++-----------------------------------+-------------+
+| Compute an alignment of the       |Set the      |
+| same genomes, using previously    |**Match      |
+| computed local-multiple           |Input** to   |
+| alignments                        |the tabular  |
+|                                   |MUMs file    |
+|                                   |produced in  |
+|                                   |the previous |
+|                                   |example      |
++-----------------------------------+-------------+
+| Set a minimum scaled              |Use the      |
+| breakpoint penalty to cope with   |**Min Scaled |
+| the case where most genomes       |Penalty** and|
+| are aligned correctly, but manual |set to a     |
+| inspection reveals that           |value like   |
+| a divergent genome has too        |5000         |
+| many predicted rearrangements.    |             |
++-----------------------------------+-------------+
+| Globally align a set of           |Use the      |
+| collinear virus                   |**Colinear**,|
+| genomes, using seed families      |**Seed       |
+| to improve anchoring sensitivity  |Family**     |
+| in regions below 70% sequence     |options      |
+| identity.                         |             |
++-----------------------------------+-------------+
+
+]]></help>
+  <citations>
+    <expand macro="citation/progressive_mauve" />
+	<expand macro="citation/mijalisrasche" />
+  </citations>
+</tool>
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/test-data/1.gff3	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,25 @@
+##gff-version 3
+##sequence-region karma 1 1
+karma	progressiveMauve	match	83032	140930	.	-	.	ID=phagey;target=phagey
+karma	progressiveMauve	match_part	83032	83041	50.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	83042	83051	60.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	83060	83069	60.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	83070	83079	40.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	83080	83089	40.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	83108	83117	40.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	83125	83134	70.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	83144	83153	60.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	83154	83163	40.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	83164	83173	70.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	83196	83205	40.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	83206	83215	30.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	140791	140800	40.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	140801	140810	20.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	140811	140820	60.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	140821	140830	50.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	140831	140840	50.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	140841	140850	60.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	140851	140860	20.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	140861	140870	50.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	140871	140880	40.0	+	.	Parent=phagey
+karma	progressiveMauve	match_part	140906	140915	80.0	+	.	Parent=phagey
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/test-data/1.mums	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,409 @@
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+SequenceCount	2
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--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/test-data/1.nhx	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,1 @@
+(seq2:0.476132,seq1:0.476132);
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/test-data/1.xmfa	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,7037 @@
+#FormatVersion Mauve1
+#Sequence1File	dataset_662720.dat
+#Sequence1Format	FastA
+#Sequence2File	dataset_662721.dat
+#Sequence2Format	FastA
+#BackboneFile	/galaxy/database/files/000/663/dataset_663935.dat.bbcols
+> 1:3292-131680 - dataset_662720.dat
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+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
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+a-------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
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+--------------------------------------------cggtga-ggtgtacaaactttggacttgtttacctt
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+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
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+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
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+------------------------------------------------------------ttcgctctcctcgttttagg
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+tctggtaagttat-------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
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+------------------------------------------------------------tgatatcatttactagaacg
+tgaacatcttggtatacaccgtcacctagctcatacgtacg-----aagtgctgttagtgatccagcatctgcacctgct
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+acttcacgccgttgcagttccagacgtcgaaggcgttggtcatcacctcctcgaagatcgagaagttcttttcgccggtc
+cggatcgaggcgtagaccgcccgctggcaggtgaggaagaactcggcgttgaccgggtcggcgcggtagtcggccgtctt
+cagccatttgttgagcgccagatcgtggttgctctcgaccaccgtgaccttcgagtccggggcctgccggcccaggatgg
+tcaggaacatcgccacctcgcgtagttcctgctcgacgctttcggagcccttgacatagagccggaagcgatcgtgcgga
+tcggcgatgttgtggtggttgcgcgcccggaagtcggagacgtcgtggacgaagatgtgctcgggccgcaggacgtcgat
+catcgacggcgtcgccacgctaccccacacccggctcccgtcggccgagcgctgctcggtcgggaagaagccgaaggtgg
+cggccgacacctcgggatcgatctgcgccacgtggacgtcgccgggcgtcaggcaggccacgcgatggccctcggtgacc
+acgccgtccttgacgaagacgtccaggtcatagaacgagccgtcggtgtcgcccagcaggtggcggcagaagaacttgcc
+gtcctcgtcgacctcgaccagcaccgcgcccaactggtggtggaagctggccttgatcccggccttcttgggaacgtagt
+tcggcttggtgaccgcgcccgtcgtcatgatctgcttggacggggtgtgcttcatcgtcggaacgctgacgagttgcacc
+ttggcgtgggggaagatgccccagcgctcgcgggtgtaggagtggaagcccgacagcgggttctcggccgtggggagggt
+gttcatctcgccgcagaagtcgatccggtcggcgatccgcacgcgctcggcgacgaggtattccatcacccgcttgtgga
+agaacgccgcgtgcttggcgtggtcctcgaacaggcgcttggagtaggtgaagccagcgatcatgatctcgcacggcgcg
+tcccggcgcaggtgctcggcataggcctccaggttgtcgacgaactcctcgtggatgtgcgtcgaatcctgggccgagga
+caggatgaaccgccggcgcccggtggtctcatccaccgtcacggtccgggcggcgggcgccggccggtgcgacagcgggt
+ccttgcgcatcgagtagaggcggttctggagcgtcgtgcgcttgacgctgtacttgcgcgagaacgcccgctggccgccg
+gccttcttgaccatcgcgttcagttcttccggcgacaccgagtagatgtcgaacggaccctcggccggcagggcggcctt
+gggcttcttgcccgccttggaagcgtgttcgaactcagccggcatagagaagctccggtttggcgctgaccggcttggac
+caatcccagacgtaccaagcgtaggcgaagcgcggggcgcccttggtgccggcgatccagcgggggcggtgacgaagggt
+gaccttcgcggtgaaagcggggtgatcgaacaggtccgcgcgcgagcgcgccgcgtcccattcgtggcggcagaggaagg
+ccacgaggccctggtcggcctccatcaggtccagcgcgtggcgcgcggcgcgctcggcgtccttgccgtagggcgggttg
+gtgatgatcgcgtccggacgcggcggcaacggcgtgctcttgcgctcctcgcccttctcgtcgacaaccgtctcgggccg
+gaccttcagcgcgcccaggcggtcgaggtcggccggcgtcagcttgaagaagtcctcgaccgcgtcgacctcgaagccct
+cgtagcggtggatgtccgtggcgaggacttcctgcacgaagggcttgagcggcgtggcgatggcgccgttgccggcgaag
+ggctcccaggcgaagaacggggcgaaatcatcgcccagggcctcgatcagggcgtcgaaggccggccgaggagtcgggta
+aaagtccagcggggtcctggcatatccggaggcgcccagcatggaggggtctttgcgaccagcatcggagagagacatgg
+tcgtgagggatgtcatggttaacgaagggtgtcaagattcacgacattgactgtcgtgacgcagcacgttaatcaggagg
+caacgggccgtccttctgcattagccccgccgccgcgccttccaggcggcacgggccgggacggtggttggtgacgagca
+ggccgaggcagcggcgggcgagtcgaaggagaacccggcgagcggcggaaggcgtcgttgacgccctcggactcgacaag
+cacgtggtgatgccggaaatcaccgcgatcgcgcggacgtctggacgttgctaggcgtaaggcaggcctgccgagaagtg
+gaaacggccggggcgggcgggacttgatctcgtccgcctttccgcctaagcttccctcattgcaggcgcagcaccgccct
+tcgctaacggccccgaggggtacgcaagggctagaagccttgcctgggacaggactgcctctgatccaggaacgccctgg
+gccgcgtagcgcccatgacgcgaacgccggccgagaatgggcgactaggcgtgacggcggccagaggccgcagcgacatt
+ccaagctcgatagagcgatcggcgggccggggcgaaagccctgtttcgagagccagggcaacccgtcataggtcctggtc
+gggcgacgaggcagcaagtcccgcgaacggagcctctgaggtggcgtcaccaagatgcagcagacgcaaaaaggccccga
+tcgcgagatcggggccttttcatgttggagcttcgggagggactcgaaccctcataggtgttcccaccagcagagatttg
+caatcccgcgcctaacctctcagtccaccgaagcacaaaaggacctcgacgcccgaaggcccgaggtccgatccgtaacc
+aggggagggccgtagctgtcccctgaccctgaacgacaggtggcgggcttggtcgtcatcccgtcaggctcgcggcgccg
+ctcgcctgaaccgccgatatgccacgagggcagtgatccgcaggtccccacaaatagcaaaaaggccacgatccgcgagg
+accgtggccttttcgttttccgatgggctgagactacacccatcagcaatcccgcttcgaggattattccccaggtgcga
+ccccaggtattccctcgacgtccaccagaccccttgcggtagtccagtccgagatcatcgccgccgttcttgcgcacccc
+gaagggattgcgggtctggcgtttgacccatcatggcgaactactcgacagttccttccccgctgggcttgcgacccact
+caccggcgctaaccggctgacgaagctcttcctatcgacacctcgcgggcttgcgacccttgagatgactccgttacccg
+aaggccggagcatttggcgacttacgtccgccactggaccagtctttgcgtttttcatcgaagcgg--ggattgaacccg
+cg-accgacagcttaagaggctgttgcactaccactgtgctattcgcaaacccaccaagacgtgctggtccagttgttcc
+cagagctttt----------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+---------gaccccggaaatgcaacacgcctcatatctttcgccttgcgggctactcgactgctcttcaggactccgtc
+tcccccaacctttcggccaggatgcccagcacccctcgaactgaagcaaagctcttcaccgcgaagtgtcgaaccctgca
+acccaaacggttatccgtactccctagacacgcttgcacgggatagtccgcttgcgacggactggcggttaaagcctcgg
+agttaccccggccccgccttgtctcccacggtcttcaggtctatccccttttgcaagaggcggccagcttcccagcccgg
+acccgtcggcttcctctgtcctcttgcgaggtcgggcggcctatgggagaccgtccctgtcaccccgtcgccggggcttt
+cgtcagaagcgacgatgacgttctagcgacagcccacgtcgtcgtcaacgactttttccgtctcgatgtcgaattttttc
+gacagtcgtggatgacgacagtgcttgacattctcgtaagcccatgctaggtgtcggaaatcgttgtaattcggacaacg
+gaactggcggcaagacaggggtgcgaatcccctcgcctccaccatcgacgcccggcgctgggagtacgcgactcctgggc
+agggagtgttaccctggcgggctgcggcccgagccaaaggtagccgggcgtcgttgatgggggcgactagctttcgattg
+gcgctcgggactgaaagacgcaacggtgggtgacctccacatcggcttgccggtgatcgggtcaggcaacagtaaatgtc
+gccgacaatgacaacgacgtcgtggctttcgcctcggctcgtgaagccatcgccgcctaataagcggtagaggagcccgc
+cgggagcttggcaacagaatcccggcaaccccctttcgcaggcgggaacaccaacaggcgatctgtcgggcgaccgattt
+ccgatccgtgttcccgtcttcgaaaggtggtcaggcctaccctcttggtgtgctatccaagggtctggccactttacaga
+acgcggggtagaggagtccggttgtcctcgtctggctcataaccaggagatcgtgggttcaaatcccactcccgctccca
+atgcgaacgccggctgttgagaacgacggcgtgacaagctcggagagaacgagcactccagtccggggtatgaggccgga
+ctagcggacgccgtagcgattgcaggcgtgacacccggagatagcgggaccggctttccgagccgcatgctcggcgcgta
+agaccgcaggcctcggccatcgggcagtgtcaggggatgaggctagtcctcggctaaccacctagcggtgaagctagggc
+atgcggttcggaaagccgggttcgcggttcgtccgctacgagatggagatgtcgccggttcgagtccggcaggtccccca
+aaaggaggccttagctcagtcggtagagcgctcctatcccacctttggtacggtggctcgacaggtaaggcatcggcctc
+ataagccgagggttcgtcccaatcctggttcaaatccaggtcgtacctccaaatcgacgcttgaccccaggccgcaggct
+gctaagcttccccggtcgggatcgtcccgcgtcctttccaaggtcaagcccccggagcttcgcttcgggggcttttcagt
+tcttgaccacccgcaggcgccgggcctcgatggcgcgctcctccgccgccacgcgcgagacgtcttgcaggtgcgccttg
+gcgatcaggtcgggcgcgcccacggcccggaagggcaccttgacggagaggtcgacatagcgccgcaagagaggctcgaa
+ttccagaccccgcgcctgggcgatccgcgacaatgcgccggcgacgatcgccacgaccaggacgttggtcggggtctcct
+tggtcagggtccagatgcccggtatcgattgtccaggatggagttcctgccgcgacacgtcatcggcggcggcgcggaag
+aggttctcgtaagggacgttttcgagcatgcgacaacgatagcgatcttttgccgcctgtctaccctctactcttgatag
+tagtaaagccctgatttcaacacaagcgctaaagacgtccgccgtaatagtcccgccacatcccctcccaatagtcgatg
+tggtagtcggtgcaatccgggcagagccggcgatccctgttggggtcctcgcccttgccgtcccaatggtagcaggtcat
+cgacgagaccatgcccaggcgccagaaggtcccacatcgctcgcagccgcccagggcgatttgctgcatctgccggtgac
+cgttccatttcgccagcggccgggaccagaggagatcgaccaccgcgtggcggatgctcccgtactgggtgagcccgact
+tgcacgaccttgcgcttacccgtccgccgggacacaccgcccatgaaccggtaggcgtcggtgtaatagatgcgcacctt
+tgggaggcggagcttcttcacgtgtccatgacctttgcgatgttgtcctccttctccttggcggcctgggcgatgcgtgc
+gtcgagcgagccgttcgccaccaggaagaagcacatgattttctcggctgtctgcccgatccggcaggcgcggtcctcgg
+cctgctcgatcagagtcggcgtccagtccccctcggcgaacgccacgtcgtgcgcccgcgtcatggtgaagcctacaccg
+gcggcctggaggttgcaaacgatgacccggcaggtctcgtcgtcctggaacttgtcgacctgaagctggcgcttgttgac
+gggggtcccgccatagatcatcgccggattgtagtccgccaacgcctcggcgagcgccctgacgacgtcggagtggtagg
+cgaacaggatcagcttgtcgccgccgtcgaggaagttcttgacccaggggatgatcgccgggagcttggccatccccagt
+tcgcggcggacggcggcgatctcctcgaagagcaccgccacggccggcggcgcgagccccagaacggcggcggcgtagtc
+gagattgagcgcccgcgagttgggcttgtcgggatcgccgtcctgtcccaccgccttgtcgaagccgtagcgctgggccg
+tctccaggatcgacaaacccaggcggatgtcgcgctggtcctcggtctcgttctcgccggccagcaccgtggcctcgtag
+agcttcagcgcctgggaaagctcgtcctcgcgcgccacgacctcgcggatttccgggctgtcgaggaggacgatctggcg
+gaacttcggcggaagctcgggtagcacctcgcgcttgttccgccgcaccatgaaggtcgagcgcagccgatagcccagtt
+cctccaggttggaggccccggtgaaattgtaggcgccgtgcttgccacgcgtgttgtcgaaccagccgtcgcagtagcgg
+tagccgaagtcgttgtagctcttccccaggccgtcgggatcgaaggccttgacgatcgaccacatctcgatcgggcggtt
+catcatcggcgtgcccgacaggaacacgcggcgcttggcgtcgaccgggttgaaccagatgtcggccagcaccggctcgc
+ggttctcggcctcggccttcttgatctcggcggcgttggcttccttgcgcttcttgcgcaccgccgccttcgagcgcgca
+tccatctgctcgccgccgaggatgaagatcgtgcgcccgctgtcgggggtcttgatcgcgtgacattcgtcg--cagacc
+aggaggtcccacggctgctcgtggatttccttggagaagcgttccagga-tgtcgtagttg
+=
+> 1:1-3291 + dataset_662720.dat
+tggtattacaagagagaaaggaagtaatcgatatgcaacagacagcagctaagaacacacaaccagaaggtttacatctt
+tacatggcaattggatcgtatgagtcggccattaacaaatatgcgcacccatataatcctggttactggaataagtataa
+gaaactaaaacagaaaatccttcagtggcagcagcaaatcagttaatacatagaagaagggttagaggagggaaaggaaa
+tgggaacaggattaaatgaacaattcgtagatgacatcgtgaaactaacgaaagaagcgggttcaaaagtggaggcagta
+ttaaaggtgatgagttatctttcagctgagtattatgtaatagacgcagacattgtaccagacccggataactacttgta
+cgaaagagatatattccatatggataatgagacagaatttcttttagaagaaacatttaataaggaggacaattaaatgg
+aagtaaatggggatgttatcctaggcggggttgcggcttttgtactttactcgtggttactatacaacagaggatacaga
+aaaggttcggatgacgcggccactattatactagatcgcatggaggaagtctttgagttatcagaagaagacaaggagta
+tagaagaaaaatgcagggaggtaaataatatgtatgaaaatgtgttagacgttatcaattgtagaacaaaagaggtagcg
+gagaaactattcgattattttgcttcagaagggtataccgtgtcattagctggtgcggagattaacacaggtacagaagg
+tagtattaactctaagcaactaacaatctttaaaccaggggaagagaggaagtataacagtgtagacgaaatggtgaaag
+acttgaatggtgtactttatctattcgaagaccaaccctgtacatttagtgtaggttgtgacgtagtgatgattatagga
+gaccagacacacttcgatgttgaagactggggagtgtacgaggatgaaaagacgggtaacgtaacgatctataacgcgga
+ttctgatagggttattacactgtttaaaggtatagagtgtggaacgatcgccacaacagccctgcaggtaactaccttag
+caagaatggcaaagttgcccgaccgatggaacgtgtctctacgtgacgatgagagccttaaatcggtaagtaagtctaga
+gctatcggactaagtgaactaacggaggagggaatgaaagatgtataacgaagaacgagacattgccattaacgatgcat
+ttgtaaatgtatatgatcgctgtccgacacaggaagagataaacgagattacagataatctacccgcacatgtcgtagaa
+gaagcaatgcgatgggggtggaacgacacgcctgtaggggacgctatcttccgctatatccaggctaataagattaaaca
+tgtaccaaaggaagtaaagttttacttgaatggtgaatatattgcaagtgcgactacgcttgatcctgctaaggtattta
+agagtggggaggggaacaaatgaagacaccaactgaatgggttgacgatatagtaggtgcctgggtcggggatgacccga
+ttaattacgcttatcatatcgcttgtttgtataatacactggacatgactatgattagccaagttataccagaggtaaac
+gagcagcaagccagttacttagaagacgtaaaagaaaatccgtataaaccattataaggagggaaactagtatggaaaaa
+acggagttagctttagacattgcaaacattctgtattctgcacagagcgataaagatgccttatggaaggttatcgctct
+gttgcaaaagaagtacctagtaatagataatcatcaccttcatcaagataacccatacaaccgcatgggcgaggaaggct
+atttagttgaatctgtccaagtgcttctagccgagtttaaggagggggagtagtatgaccgaggaaaataagtacacaat
+agagctgaaaagtaaaacagtagaggaacatattatgaaagaaaaacaccttcgtaagatgctccataaggattgtaact
+atttggttctttctaaaataatgtataaacgaatgatagtagaggcccaacgagcaatattaggtgaaatagacgtaact
+gcacctgcttttgactatacgaaatacattgaggagccaaacgagtatatgggcatgaaggttattgttctcgatgacga
+ggacgagacaattaggatagggtaagtataccggcctttagtagcacaccacgctaggggccggaaaataaaatcttttt
+tttaaatagttgttgactttaaggaaaccgtattatacaatagagttacagataaggaggagataacaaatgataattca
+aacagtacttaaaatgtacgactcggaggggacgctagtgtctcaacgcaaagtacactcacctacagaagctacaatag
+agaagatgatggacttaacacccgatgtagtctacagtgagctagaaactaggtatgttaaaacgaggtcagaaaatgca
+aaaaattaaagacggtctatatatcataggagctatagtcgggtttattctctttcttatgatagccgctttcttactaa
+caaatgtatatgatgcagaaggaattccagttataacgctcatcggattatgttcggccatcggaacattactactagac
+ttaacaattgagaggtggaaagaggagtatgaggaggaagacaaatgagtcagctactggttactataatcggttctgca
+ataggttctattctagcaataaccatcatatcaatattaaagagaaaataaggaggaagaaggaaaatgagtctaatgtt
+attcattcaaattgctttaactgttatagcccttagcggggttgcactaattataagtatggtgttcttaacaagatcaa
+ttaaccgtttaaaccgtgcaacacttagaaacttggatacagtagaaaggatgagacgtaatggagccgtataaaattat
+tgaaatgttacagaaagcagatgttgatccaaacatacatagtgtactcactctagactatctaacaggtatcgactcat
+tagacaaaggaaaccaaccaactgaagaagaatggtacgctatgggtctagtagaaggactaatcgagggagggaataac
+aaatgagtagtactaaaacagcaaaagcggaggaaaaacgtgttaagcacattatggactctctaaccaggtactatacc
+gggaaagagaa
+=
+> 1:131681-159457 + dataset_662720.dat
+gaggttaaacgtatatcggacagccatctgaaagataaaccttttactaaggtaaatgtacagatcgcgatggatgaggt
+aggaaggtatctatatcaagagacttgttactacaagatgatgtacggtatcgagctagacaaactgttcttaggtgcgc
+tagaggatgaagattaatttcttcatctttttttttattttattgttgactaaacgtaaacctgtatgttagagtatagt
+tataccaattaaggaggagaaaataaatgatagcacctaataaaatcaccttttattgtaaaccggccgatatttccgga
+gtccaccacgctttccctgtggactcttcagctagtcatgattcagctcgatattgggctacaggtcaatatagttggca
+gatagaccagaaagaccctataacatttgaatggaataatggggggttcgatcatgttacaatcgagagcttagatattc
+gaggggaaggtggtcgtgcttaccaggttatcgttaaacgtgatggacatttctttaaggtggatttacgtgaagctact
+cttatggaagttattcttggtcatggcatccaagccggtggtcgcttaaatggctccttctgcttcgctaaggagggttc
+acagacaaaactaatactagaaggttctgacacacataaagaggccctagcggagcgtatgaagcgtgagaagtacacta
+agaagattagtaacaaagatttaaaaccgggacatgtgtattcaactatctcaggtaaatctaagttgttcctcggttgt
+gtatactcagccaatattgacgaatattcaggtaatatcagcaaagtctataaaggtgtgttactagcagattgggacaa
+atggaataaagactatattaaaaaattcctagaaacaggtgaactagtagaaggtaatagagtatacagcggtaattttg
+atgtggttaagtctcactcctttaagatagagggagagaaggtagcagacgtagacctagagccacttgttaaacgtcta
+aatgatcttggcatgaatgaatacgaggagaaaatgggcaaagatcgacacagtaactatttatggggttacactggttc
+ttatgagttagctaaaatgcgtacaaaccgtaaagaggtagactttaaacctgcagatattacagccatgaaacagcaca
+gagatagattctacaatagacgtttcttttaagctaaggtttttatatacttcttataaaaaagttgttgactataactc
+aatgtatatgctagtatataaatatagcaagacaaaccatataagggagagaataacaaatgacaaaagaattcacaatc
+gattttaaaaatgattttacagaagcagaggcagcatcacttaaccctaacatccaagtacatacaaaagaagaacagat
+tatctcaatgtatcaaaacaatgcaacgcttaaagaaattacagacaagttaacagtgtctacccgtacgatctatgaag
+tgttggatgttgccggtatcgagaaacgtacaccaaacgttacaaagaaacgcctagctaagttagacaaagaagataag
+aaaatgattgtagatgcttacaacgaaaagaagtacacagtaaccgagttaatggcaatctttgatctgaataaaaatac
+actatatacaattctagatgaggctaaggttcctcgtaaatacaagcgaaaagaaaagaaaccttctatcattcgtgttc
+gtcgtgatggggacgagttacttattactcttacgaagcatggccaggagtcagttaaaaaagtctctgtaacttacgag
+gtgtgatatgaagatcgatgctgctaaagcttattttatactaaactacctacaacaaggtggagaagtttactacgaag
+gcagaacgctagtgtggttagacgaacgtattgtagatgaagatgaaaaacacaagtgggtaatcgacgggctagctatt
+aagggtaagtcatacgaaggtacagagtactttgataacccggatggtggaaaggtatgttatatgggtcacgatatgtc
+gatgtctcgatttatcagctttgttaacaatatgtcgccagtagagtacaatcgaattattagaaaattaggagggaaat
+aagatgaaaacaatagcagccataataggtgttataggagcgattgctcttctaaccttagtggtaaactttattcctgc
+aaccattatataccttatcgcagtaaaagctttagggctcggcctaagcttctggcaaacatactgaggtacctacttag
+ttgtatttgtttgcaacttactattcgggggcgtacgtgtaacaaataaataagttcaccaatactgggtacattaattt
+gtatccagtaaattttaaaatactcattgacttaacgtaaataagatgttaaactaaatgtacaaactaaaacagagagg
+gatgttaaatatgaaagtaatgacgcttgtattaggaaaccaaaaagctacagtaaaagaggaaaacggtgtggttagtt
+taattagaggggatcaagaaacaaatttcagccctaagcatacattcgagtcagttacagaagattttaaagccttcggc
+tgggaggcagctttagctattacaccaggtgagcagcacgaaaaacttgagaagtcctggttaatgggcgaacgcccagg
+gccaccaatagaaatcgatgaatttatgactgtagctgttccaggtaagatcacggaaattacttcttactcaggcggta
+cagacgacaaagtagtagagcgtgcagtaagccaagaagtccctgtagctgttcaaaaagaagtagatgaatatatccgc
+cttcatgagcaaattgcagaactaaataaacgtgcgaagaagttaaaagaaggtgtacgtgggtacatggaggataatga
+taaaaaagaaatttacggtacagaaggtaagaaggttgtgctacaaccagcagctaagactaactctacgtcaacgtata
+ctgattatgagtaccacgaggtagctacggtcttaaatgagcacaaacttgaagaagtatcggaaatgcgaattaatgca
+gataaattaaacagcctggttaagacgaagaagttacctacagaagtagcagataagattaagaagatgaaaattgcaat
+gccggggacacctaaatttacagttaaaagttaaggagaggtaatatggaatcctttttcgaaggtatacgtactatgtt
+cggtgacccggactttctaattcctgtcattatggtgtgggctggttttttacttgtaacagctgcgttaatattgagtg
+tgattatataaaggagggaaaatataatgggtgaaccaattgttagaggaataggtaaatttattgtattgaaaaatggc
+gatttagatcgttatctagacgatgagttggaatgggatttgtataatattgttcagactatagctgctggacggtctat
+agagggtaaagtagaagacaaccactacattgtggttaacaaagatgaaccctatattgacgaggttattgcagttctaa
+agaaacatggccattggggatgagaagggtaacaccttctcttttttctcacataatttactaaaaaagtatggacagga
+tataaagctgtatgttagaatctagatataacaaaaagggaggaatttacaatgacaagagtagaatttttaacaaatga
+agaaatggtggagttagttatacaggcgcaggcaggtagtgaggatgcagagaacgcgattattaaaaactgcgaacggc
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+=
+> 2:1-53548 + dataset_662721.dat
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+=
+> 2:107128-221828 + dataset_662721.dat
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+cccatgacgcccaaggcctgagcctcgaaaccgtccacatggttttcgcccgcgaactggcgcaacatttcgaccacgtg
+atttccgcccccgtggtcgaaagctggcgcgacgaggacaccggcgccgaccacgcgcaagccgccgtttgcttcaccgt
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+ccgactgcgacgccccggccctgactgtcacccactgcgacggccaaacggtctatgtcggcgctctggaagccctggcg
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+ccccatggctcgcccctctgacctgctcaacgtcaacgccgcccgcgtcctggcttgccttgagcctatcgccgccgccg
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+aacctcacggaaaccgaccgccgcaaggcctatggcgcggcctgcgccgccgaagccctggcgctcgctaacgcctatca
+gcccgccaccctgcaaggcggcgccgtccgccgcgctctgggcgcctatgccgccgccctaaaggtcctgctagacgggg
+agccggtcaaggcggtgcgcgccgccgaaggcgcggcgctttcggtccgcgctcgctacgccaacacccgcctttaacct
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+gaccccgcaagcccgcttctcgtcgccgcgcgtcctgatccttccgggcgcggctcccatgccgattcgccagccgcgcg
+gcctttgcgccgtcgagtgcgtcgcccttggcgtgacgctgggcgcggcgctctacctcgccgcccgcgtgttcggtctg
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+tcttttttgattcggagggacccaaaggccccctacgttaaccatttttggcggcgccccc
+=
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/test-data/2.xmfa	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,6309 @@
+#FormatVersion Mauve1
+#Sequence1File	dataset_662722.dat
+#Sequence1Entry	1
+#Sequence1Format	FastA
+#Sequence2File	dataset_662722.dat
+#Sequence2Entry	2
+#Sequence2Format	FastA
+#BackboneFile	/galaxy/database/files/000/662/dataset_662723.dat.bbcols
+> 1:83043-149557 - dataset_662722.dat
+acagtagtacctaacccgactccgaatatagttgtgtaatccttattcttgttcagtctaaaactaatcgcagtaggtaa
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+--------------------------------------------------------------------------------
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+---------------------attggtacgattgttgagatgagcacgatatcgaataagac----aagggtagttactt
+cgaatgcactgatagtagaagggagacta--atattggtcatcgtcttagcacccatacccgagatcatatcggatactt
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+--------------------------------------------------------------------------------
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+-------------------------------------------aacgggacaacaagtaatcgagttaaagactgcctag
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+gtctctttctcttatggcatcggtcagtctcatttctttttctcct----------------------------------
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+---------------------------------------------cttttttcttagt--gaccgagggctttttaccct
+cggatggtttactttcactgagtct--agatgttaaatatttatgta---gtttaccagtgaatga-ccccattatacat
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+------------------------------------------------------------------gacgcgcgcccggc
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+cgttc-tcgatcgccgacaccatcctcaa---------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+-------------------------------------------gcccctggtcgtcgaccagaccggcggaccgggtttc
+caggcggcgggcgcggcgctccagggcctgaacatcactccgccgggcggcggcggcttcctgtcgggcctgggctcgat
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+gcatc----cagggacacctcctttcatggttaatgcccgatgccgagct-tccacgac---------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
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+--------------------------------------------------------------------------------
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+----------------------------------------------gtcctgttccccgagactatcagctacggctcgt
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+=
+> 1:1-83042 + dataset_662722.dat
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+=
+> 1:149558-159457 + dataset_662722.dat
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+=
+> 2:1-61895 + dataset_662722.dat
+gggctctgggcgaagttttgtgggactactatgacttgcattatttcaagcgcaagcggtccgagtggaagtaccaaaga
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+=
+> 2:118871-221828 + dataset_662722.dat
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+gcgggtggtggtcagcgtcgactcggccaacaagcccggcgcccgcaacgactacagcgtcgcccaggtctggggggaga
+cccacgcccgcaagcactacctgatctaccaggagcgcaagaaggtcgacatcaccggcctgaccgagatgatcgagcgg
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+cggactgtaggtttcgtgacaaggtgagatattccacaacgatttcaaaggcttactgcgatgtcgatccgcacgttctt
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+gcgatttaccaccgccacgttaacctaacgcctgttaacctatcggttgttaaggttaacgccccgttagggttaacgcc
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+aggagcttcccgccatggtccccgactcgatcatgaacccccgcgaccacttccaccgcctgcgcgaggaaaccgcccgc
+gctctggtcgaggccttcgccgaatccgaccccggcgaggattaccgcgccgaggaaaaggccggcgcgtgggttgtcgc
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+atgtcggcgccagggtcgccctagcccggcgcgtcgccgcgccttcggagaaaaccgccatgctctacacccccgccgcc
+cgccgccttcgcggctatcgcgaaaccgccgcgaagaacgccgaaattcacgcccgcccgcacatggccggcaacgtcgc
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+gccgaagaggaacgcgaatatcaaaccgcgtggcaagcgggccagcgctacgccgaactcggcgccgaagccaaggaggc
+ccgcaaggaagcgctggcgatcctcgccgaacgccgcaaggtcaaggggctggaaacccccgccttgtgcggcgcgatcc
+gggcgcaagtcgcggccctgctaggccggatcgaagaggcgcgcgcctcgcgcgccaagctcaaggaaggcgaggactcg
+cgcctcatgttctacccctccgccgccatggtcgcggccttcaatgacggcgcggcgtcgtgaaggtcgcccgcgatagc
+ttcgccgtgttctggaccctcccgcaaggcggggtccaatttcacgccgacataaaacgggcgctctatccgaccgcccg
+cgacgccgcccgcgcttttagcgccatgttcccccgtgaccgggtccggagcgtccgcgacgcctccggccgcttcctgg
+ccttcaaggagtccgccccgtgcgcctgacaagctacaacgtcaacggaaccggctttaagggcggctccgccccgcccg
+tccccgcccaaggcctgaccggtcacgccgacggcttgaacctttgggttccctcgcgcgagcatatcgccgccatgctc
+ccgcaacgctggcgccacgccttcgcccgcgcgtcgttttggtatgacgcgcacgacaataaaaagccgtgtcgcgccga
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+tcttccggggcgtttaccttttgttaacctctggcctctagggtgactttcgccgccgggcaatcccgcccgccggaccc
+tctttcaaggattgctcccgtcatgacctctcattccatggtcgcgcaccgttgggcgcaggacgacgagaacggccgca
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+gaccgcgaaacacctttcccacatccgccgcgccatcccgtccgggaccccctgcttttccgtgccgcacgtgtcgcgga
+tgcacaagccgggcgggtcgggcgacttccacggggacaacctgcgcgcctatgtcgagagcgccgccggcctcgccgaa
+aaggccaagcgcgcccgcgtcaacggcccttggctgcttagccaagcccgcgaaaccctcgccgaagcgcaacgctacgc
+cgacgccttcaagctgaaaaccaaggttccggccttggaagacgtcgccggccaatgggcgaagatgacggccgccaagg
+cgcgggccgaagccaaggccaagcgtgacgccgaaaaggccgccaaggcgcgccgcgaagccgaacggctcgccgacgcc
+gaagccttcgccgcttggatgcgcggcgagcgccagagcgccccgtttagctaccgggtgcgcgatgacgggaccgtcta
+tcttcgccgcttccggggcgtggtccgcgacctgcgcagccaagagcgcgacggctcgcgcgtcgatgaactgcaaacct
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+ccggccccggaaggctacagcgtccagcccctggcgtcgttcctggcctatctggagacggtcggggatagcccttatga
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+ccgctccccatggggcgcggcgcccaagagtggatgcgcgcgcgccgcgaagccgtcgccagctacagcgacgacaaggc
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+accccgcctaagaccccgcgcgccgccctggccttcgccggggcggctccctcaacccctcgcaaggatcgcaccccatg
+accgcccgtaagcccctgaccaaggaacaaaaggcccgccgccgcgcgacccgccgcgccgcccgcctcaactggtcgga
+tgagcgccgcgctcgcgaattcgagcgtcaagcccgcttcttcctgatgatcgccacccgcgcccaaggcgccggccaag
+gccaggaagccgcccgcctcgccacggtcgcacaacgcaaggtgactaactggcgcatggcgcaggcctgcgcccggatt
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+gccgcccgccgcgacgccgaacaagcggcgctagacgccttggaggccgaagccctggccgaagcgccgggcgacgtgat
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+ccgtcccgaactacgccgtaagatcgcagcgcctcgccgacgccctgagtcccgcgcgaaattacgtctatcagccccgg
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+cgacgacgccgacgccttccgggccgaattcgccccgtgggttcacgccgccaacgtgacggccgaaggcgcggccctgg
+cctcgatgatgaacccgaccgccgaagagtatttcagccccgccacgggggtctaacgcccgtggccctgaccttcgccc
+cgcaatcgacgcgctacgccgtggaagtccccgaacgcgactttctggccctgacccgcgccgaggaaattctagcccct
+ggcccctatctggagccgtcgcttagcgagcgtttggaggcgcaagccggcgtttgggatgtcgagtataacggccattt
+cggcgcggccgtttacttgacgctcgacgttgacgccgactccccggccgcccgcgacgccctggcctcgatcatcgccg
+accaactggccaaggccaaggcgtggaagcgccagcccgcctaagtcatcattcctatcgtctatgacttgtcaccggcc
+gaactcttgcccggtgacagtctgggcaagtaaagctcactctggattttatgacttagcgcaaaggattgaaattgctc
+gaaaaattcctcgaagctcacaaagttgttttctggctgcttttgctggcctgtttgtggcgcttttaacggtttgttaa
+cccctggccctctagggtcgaattcccggcgcggcaatcccgccgcccggccttccttcggagcttctgatcatgttcgc
+ttccgtgacccttcccgcccatgacgcccaaggcctgagcctcgaaaccgtccacatggttttcgcccgcgaactggcgc
+aacatttcgaccacgtgatttccgcccccgtggtcgaaagctggcgcgacgaggacaccggcgccgaccacgcgcaagcc
+gccgtttgcttcaccgtctcggcgacccccgccgcgtgggaagccaagggcgggcgcctcgcgcgccggctggaaaacct
+cgccgcgcgctatgccgccgactgcgacgccccggccctgactgtcacccactgcgacggccaaacggtctatgtcggcg
+ctctggaagccctggcgcgccccgccccggtgcaaggcccgacccgtgaggcggacccggctttcctcccccgccagcgt
+gaggacaaggccgcccgcttcgatcgcctgaccgcctagcccctggcctccccctagcgcaccgcccctagaaaggcggt
+gcgcttttctgtgtctgtttacttgttgttaaggaatagcctgctagtgtccccttgttggcggacgcatcccgcgcccg
+cccctttctggatcgctccccatggctcgcccctctgacctgctcaacgtcaacgccgcccgcgtcctggcttgccttga
+gcctatcgccgccgccgctaagaccgccccggccgccgaccgcgccgccctttcctacctgctcgacgctggcgagtatg
+tcgccgcgtggcgccgcaacctcacggaaaccgaccgccgcaaggcctatggcgcggcctgcgccgccgaagccctggcg
+ctcgctaacgcctatcagcccgccaccctgcaaggcggcgccgtccgccgcgctctgggcgcctatgccgccgccctaaa
+ggtcctgctagacggggagccggtcaaggcggtgcgcgccgccgaaggcgcggcgctttcggtccgcgctcgctacgcca
+acacccgcctttaacctcttgttaacacctcccggctatggtcgggaggtcgcaaggagacacccgacatgacccgcccc
+ggccccgcctcgctcctgaccccgcaagcccgcttctcgtcgccgcgcgtcctgatccttccgggcgcggctcccatgcc
+gattcgccagccgcgcggcctttgcgccgtcgagtgcgtcgcccttggcgtgacgctgggcgcggcgctctacctcgccg
+cccgcgtgttcggtctggtctgaccagacccccgccccgcccccggtcggaccggtcgggggtgtgtcccataatgacac
+acccccgccacctagtatcttttttgattcggagggacccaaaggccccctacgttaaccatttttggcggcgccccc
+=
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/test-data/3.nhx	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,1 @@
+(seq2:0.476132,seq1:0.476132);
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/test-data/3.xmfa	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,6309 @@
+#FormatVersion Mauve1
+#Sequence1File	dataset_662722.dat
+#Sequence1Entry	1
+#Sequence1Format	FastA
+#Sequence2File	dataset_662722.dat
+#Sequence2Entry	2
+#Sequence2Format	FastA
+#BackboneFile	/galaxy/database/files/000/662/dataset_662724.dat.bbcols
+> 1:83043-149557 - dataset_662722.dat
+acagtagtacctaacccgactccgaatatagttgtgtaatccttattcttgttcagtctaaaactaatcgcagtaggtaa
+gttggccttaatccgcccgcttacaatatctgcactaggatactgggtagccaccactaaatgtatacctgttttc-ctt
+gccttctgccctaaccgagcaatataatcttctacccctttgtcaacagcacgtaaatctgcatattcatctacaataca
+cactagatagggtaacggctcctccgctacttcattatacaaagataacaacttcgtacctttttccttcataagagcat
+atcgcttatccatctccattgtcagccctgctaatacttggcaagcttctttagcatctgtcactacgtctagtacgtgt
+ggactatcctcatacttacttagctctaccatagccgggtcaatcataataaactgtagcttttcaggtggatacattaa
+catcatgcttacaataatcacatttacgaagaccgacttaccgctacctgttgtccctgccaccaataaatgtacacatt
+cagtcaaagatagatagatcggctcccctagtgtatctacaccagccacgaacattaattctttttcttctaccatactg
+ataaactcctcggtttcaaccagttcacggagactaataaccggtgaagcagctaaaggaaccgtaaacttaaccgtgtc
+ggcaatatccccattctcaacacctaacccgctaatacctgttgcagctcgtaagtcattaatggacttttcaatcttag
+aaaaggttacatctttaggtatacttacctggacaacccctaaccgcaccccacagtcaatccgttcattgtataaccta
+gccgtatcaatcaattttacccgcttcataccttccgctagcttactaactattccttcatctagagtaccttgctctcg
+cttatacataggtaacagatcaaatgggtacgccttacgctccactacctcttctaatactttttccgttttctctactg
+taccacctaataaggagaatacttcgtttaagctaagtagttgatcttttgtgtaagctgctaatacacagtcagtatag
+ttagtaataaattgtttatctgacgacttaaccagtttcaactcgtttaaagccgtataagaccctagagcgtattgaat
+atactggatgatatcgtttaccctctcggacttaactgctattctgagctgaaattggaagcactcactctttatcttct
+cttctgctaacggttcgtaaggcttgtaatcctctggctgtattttgtttaacactcgaacagctttatcctgcagttta
+cgactccatctagaccaagaaggtttttcgttcccttgaatatagctatcgtacatatcaattgcgcgatcttgccaacc
+ataccgcctgcgtaataaccattgcgcatgtacctcttcatcaggatgtaaagccaagtccagtaaatcagtaaggaaga
+ggccgttcttatcctgtctgagagggagaaagaacgcttccgataaatacccctcgaagaaattaaaaccctctgtaggc
+gcttctcgatgtcttagaacaagttctgccccggtttcgatatgagagggtgcaatgacaaaagtattagccccctcacc
+ggttaaatgggtctctactccgaataccgaatcgttaatctgttcaaggatatcgacaaagtgaccttctatatcttcta
+caggcataaacaagttagctaggttatggtaatttgcagaaagctttttcatcttctctcccccttaatatgcttcataa
+ccattaaactgtttgcgatctgcatcccgctgctgaaaacaagcgaggtaagattaatgataattaatactgatactgta
+ctcatgttattcactccttattttctttttggtttaggcgtagacttacctggttttggtactggcgggtggaaacgttg
+catacgagtcttacctacccgctcaggagtttgtaatcgctcgtgtaccttctttacaacagtagtaggtttacggataa
+tgtccactgtatctcggaagttacgaactgttttagagactgtatctttagctggtgtatatactgagtcaaaccctgat
+ccattatctaagtgtttacttacaaattttggaggagagcttaactttgagaacccgccaatggtgaccagtagctttaa
+gataaatccagtgaagctcgcaggggtcggtgtgccgaacaatacccaaccgatcactagaagaaaaatagaatagtata
+cttgaacaagagacaagtgtttaacatttcccaaccatgtgttaaaataatttctatagctgtcaaatatccagcaggtg
+caggcgagaggacttactagcccgagcactaacaaatcaaagaaccggcgaccgtttttccacagc--------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+---------------------attggtacgattgttgagatgagcacgatatcgaataagac----aagggtagttactt
+cgaatgcactgatagtagaagggagacta--atattggtcatcgtcttagcacccatacccgagatcatatcggatactt
+tattcaacaattg--aaaacctttttgaaacacaatcggtaaaacagttgtgaatccagctaccacaaaccaccgtttca
+taatggtctgtaattccattggttgactatttctagtacctttcttgcgaagaccggaaatcatacgtttcatagcttcc
+aggatagtaaggacagatactaatccaatagataataagctaaacatataggtagtattttcgaaccattcattatcgaa
+taaccataaaggcgtcttcaatattaagtctgaacataactcatacagccatgccattaaatcaactgagccttgagcaa
+tgttgtgaggtaggttatgccaccattcctgtacactggtaatcatatcaccgatttgtcgcattacgtttggggcttct
+ttagcgttttcgattactttcttagtagaatgaatgtgtgctttcaaacctgtaggattatcaacaatagctgcgaacgc
+ttgggaggaatttgcggtgatgaaggttgaggatagtactgca-------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+-------------------------------------------aacgggacaacaagtaatcgagttaaagactgcctag
+agaaggtaaatttttgaatacgatttgagctaggtaaaacaagatacttaccaacggtacggctactaaggactgtacta
+aaccttttagaatg--tcgctgctccattggtcggctttttcgccctttctcatcattttgtagaaactggctacgatta
+acattatcatagagagacttacacttgcgcttact--ccga-gtaaagctagagatgacccccattttagcaccatactt
+ggagttattgtttgacttgctatatccgttccagcagctaaggctttgggagctacctgggcacttgccactaacactgc
+cataacccctcttagaatctgttttgtctttctggtttgtcgaggatgagacccttcttgaatttctttctgaagagcct
+ctagggtaaaaaccatatctttctccacatcatttactaatgaaacttctttcaccggctgaatataacgaacgccttct
+gttaaccctctagattgaatatttattttcatgttaatctctccttataagttagttgattttacttaatgtttgttccg
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+---------------------------------------------cttttttcttagt--gaccgagggctttttaccct
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+cgttc-tcgatcgccgacaccatcctcaa---------------------------------------------------
+--------------------------------------------------------------------------------
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+-------------------------------------------gcccctggtcgtcgaccagaccggcggaccgggtttc
+caggcggcgggcgcggcgctccagggcctgaacatcactccgccgggcggcggcggcttcctgtcgggcctgggctcgat
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+----------------------------------------------gtcctgttccccgagactatcagctacggctcgt
+caggcgggccgaagttcaagaccacgatcttccaggccgacagcggctttgagcagcgcaacaaggactggagcgacatc
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+ctggtatcagaacctcgacatcctgatggc
+=
+> 1:1-83042 + dataset_662722.dat
+tggtattacaagagagaaaggaagtaatcgatatgcaacagacagcagctaagaacacacaaccagaaggtttacatctt
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+gagatagagactaaatactgctatattataaatatacacgtttgactgataaatgagaggtgagatgtataaatggctat
+ctcaacgctaagatcacatattacagctgcaattgagctacagcagaaacaagcgtctgcctattttgttattggcaaga
+caacagcctggacgaacgagacaaacccgccagaagagacagaggatgtatcaactatctccgaagtaattgggtataag
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+aagatttccctacaggtaacgcataccgccaagtaggtttacacattggtctaacccctaaatccggtgtaacaaaacca
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+ttaatgaactacaatcaatccaggaacacaatgtacgtcagttaggtgatagtatcttcgcagacggggatatccaaaca
+ggtatgtccttctcagtaactaacggtaagctcaaggtagaagacggcctcgtatacctagcgggtcgtgtacgtgcatt
+taaagagcaagaaattgattttaccggcgtcggtaatgagaaaatcggtattaaacttgcgcagtctgtcattacatcag
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+accagagttttctactttaaacgaagtacttgctcaacgtacatatgaagaatcaggttcttaccaagtagaaggattca
+aagtatgggcagagaaaagtcaagatactactaaagtagatttagttattgaccgcggtactgcctacgttttaggttac
+cgtattaataagcctacgtcaacacgtattccgttacgaaagtctacagagtttaacaatgttactcaggagactcacac
+gtacgatacagctgttcgaaagaataaggtaggtagttcatctgttaagcaagtaaaccaagttctagcccgcacacagt
+cgccagcaggcggtttaacagtagctaagggtgcaaatggtgggcgagatgctttaccagctcagtacacgagcctagac
+ccaacaactgttagcttatggacaactagcccagatgtaatctacacatacggtgcagactacaccatcgttgaagacag
+tg
+=
+> 1:149558-159457 + dataset_662722.dat
+gttagatggtaagggggatggggttattcggttagcgagtggaggggactttattcgtttccagagtcctatggtcagtg
+tggatgagaagagagagcagcaggtttgtcgagatatcttcaccttctatcaagggagccgaattgtggactacaagatt
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+tatgctcgcagaatggaaagattgagcctgtataggcttattttttttgtccgttaaaccgttatattactaataagcgt
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+tataatcttaacgtccctctttatatattatttaattatttataaagatatataagagaataataaatataataatacga
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+aggtacctctaactctgaaaatttatcaaaatagttgttgacttttagtagtatgtcccgtatacttttgttatgagtta
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+aatttaccttaccgattagacaagtttaatagaattttaaactgtttatcttggcaagtagtagctgactcgacttgcga
+taaattaatccggagacaggctaacgaggtacgaatggtaaaacagttaagcacctattaaaaaggagctgcttaacaat
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+aaatgactggattaaggcgtgccactatttcagagatgtctcgtaattcacggtctgttctgaataaggtacatgtagct
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+ataaaatggatagtgtacaaaagtttatttcagaaaatagtcaccaattcggttatatcatgcaagaggctagccgtcaa
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+gattttagacaagttacaagctattgaagaggctaaagtccctaaaaaagatgtgtataaggcagttatctcgggacata
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+acagatgttgaatatgagctgatcgaagagttaaaacataatcttaaatataaggaaagccacttctttacggctattgt
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+gcgtacgcagaacgagaagggtttgttccttataatggtattcttatttgtgggttctatagagagtacaagagcggaca
+ccgggacttactatttgtctcaccagtgaaaataaacgagcctattgtggcttgtttggaggagttagagtgagcaagtc
+agatataactcgtaggctagaaaaggcaatttacacggcgacgattaaacaaggtgtgtttggttgttttgaggttacaa
+tcggttggttcgggaaagagcgtgtggatttcataacctacgacacaaaaaatatctggcgatgctatgagattaagtcc
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+tgctaagatagcaattcaagtattacatgcagcgggatataggaaatggataaaaggggagccgtactaccacaaacgat
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+attatgtatctaattttacaggtacagtaagaagccgagaggaagcggaagacatcttgggtaactatctacatagcttc
+agtaccgtagagaaaatggtcactcgactgaatgtagaggaagcggaatggaagagaattaagacgcatgttacactacc
+taaaaacagtatatttgtctacccgaaagttttataaaaagtattgacaggtattggttggtgtagtaaactctaactat
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+taccctgtatcagataaaaagcagtttgaatataagttatgtatgctaaaggacaaggagtacgtatcagtagctgagca
+gcgcatgacagacgaaggctggaagtactacggaaacaaaacgttagagatgagtgtatacagacagttagtagcattta
+tggacaaccgttaatattttagtaggtggttgacttatagcatatgttagccacctatcatactaaaggaggagttagta
+atgcggagaaaaattaagtgtgaattgtgtgatggtagcggtgcctcgccttggtctgctctaggagggccttgtataca
+atgcgagggtgcggggtttctatttgaacctgaagggaagcctaagtttaaggtagacttcggtgagttagacgggctta
+ctaaaatggaagatactacagacttaagtgatccacatattaaaatagatatgaacggcatcagctttaaagacaaggat
+ggtaactggactgatccgacaaaaccattcgctaactttgaaaatatcacaattaaccactcaaatggtaaaactataaa
+aggcgggaaaggggttctgaaaccgatgggattattcgatgattttatggaggctattgaagcagaagagacaggaagac
+caatcgtaaagcatttgctagtttggagtgttgatgagctactagaccttcacaacgattacaagcagctgtacgatcta
+tttaaggacgaggagtacttgctatatatgaaggacgtactaaaagttataaaagcaaaaacaaattagtagtcattctt
+tatagactgcacgcatagtataaactataacaagaagggaggaattacagtgaatgcggaagataaacgaattctaatga
+aaatagtaggaagtatagccgggatgtttataatgggatacctattcggtttcctaggggttattattagtttagtagct
+atttactttgtgtttaagaatgataatggtaagcaggtaggagaagacccggagagtgaagctaaggccgcctttatctg
+gttctgtgtgatgctagtgttagggatcgtgcttgcgtatctattcggtatcattggagtaattatcggtttagggttaa
+tcgcaggagccatctataatataatgttcgggtaaataaagaattttttttaaatagttgttgactttaaagaaacatgg
+tgctagaattagcttatcaaccaaaggaggtaacaaagtgagaataacacatgaacagaagatggaaattctcgaagagt
+ggaaccttataggagagaacgattgtagaacggctctacctcacttaacagagctacttactaaaatacttgatagtgtt
+tctgatcctgaaaagataaactgtgggtgttatgtgtggagtgaaaaactacaagagcatgttgaacctaatccactctg
+taagaaatgcggcgggatgggttggtattacaagagagaaaggaagtaatcgatatgcaacagacagcagctaagaacac
+acaaccagaaggtttacatctttacatggcaattggatcgtatgagtcggccattaacaaatatgcgcacccatataatc
+ctggttactggaataagtataagaaactaaaacagaaaatccttcagtggcagcagcaaa
+=
+> 2:1-61895 + dataset_662722.dat
+gggctctgggcgaagttttgtgggactactatgacttgcattatttcaagcgcaagcggtccgagtggaagtaccaaaga
+tttgctttggtttatcaacaacttgccgacgcggcctcggacacctccatcgcgtccaagtttcagacctacgatcacct
+gccccacctggagccgaaggtgctcaaggcccggcttgacgcgggtcacgccgacgagcgcgggcggccgattccggacc
+gcaaggagcacttccggcgggtggtggtcagcgtcgactcggccaacaagcccggcgcccgcaacgactacagcgtcgcc
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+=
+> 2:118871-221828 + dataset_662722.dat
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+gattcgccagccgcgcggcctttgcgccgtcgagtgcgtcgcccttggcgtgacgctgggcgcggcgctctacctcgccg
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+acccccgccacctagtatcttttttgattcggagggacccaaaggccccctacgttaaccatttttggcggcgccccc
+=
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/test-data/4.mums	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,409 @@
+FormatVersion	3
+SequenceCount	2
+Sequence0File	dataset_742014.dat
+Sequence0Length	159457
+Sequence1File	dataset_742014.dat
+Sequence1Length	221828
+MatchCount	402
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--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/test-data/4.xmfa	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,6315 @@
+#FormatVersion Mauve1
+#Sequence1File	dataset_662722.dat
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+---------------------------------------------cttttttcttagt--gaccgagggctttttaccct
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+--------------------------------------------------------------------------------
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+-------------------------------------------gcccctggtcgtcgaccagaccggcggaccgggtttc
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+--------------------------------------------------------------------------------
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+----------------------------------------------gtcctgttccccgagactatcagctacggctcgt
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+=
+> 1:1-83042 + dataset_662722.dat
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+accagagttttctactttaaacgaagtacttgctcaacgtacatatgaagaatcaggttcttaccaagtagaaggattca
+aagtatgggcagagaaaagtcaagatactactaaagtagatttagttattgaccgcggtactgcctacgttttaggttac
+cgtattaataagcctacgtcaacacgtattccgttacgaaagtctacagagtttaacaatgttactcaggagactcacac
+gtacgatacagctgttcgaaagaataaggtaggtagttcatctgttaagcaagtaaaccaagttctagcccgcacacagt
+cgccagcaggcggtttaacagtagctaagggtgcaaatggtgggcgagatgctttaccagctcagtacacgagcctagac
+ccaacaactgttagcttatggacaactagcccagatgtaatctacacatacggtgcagactacaccatcgttgaagacag
+tg
+=
+> 1:149558-159457 + dataset_662722.dat
+gttagatggtaagggggatggggttattcggttagcgagtggaggggactttattcgtttccagagtcctatggtcagtg
+tggatgagaagagagagcagcaggtttgtcgagatatcttcaccttctatcaagggagccgaattgtggactacaagatt
+gctgtcgcagataaaccgttagagcccgtacaagacgttttagaagaagagaaggtaaatacaccagaagagtgtaaaga
+gacccctaagcaagctctagaggcgttagaggctatgtttagcagtacagaggatgatcccctgtataaattaaagaaaa
+ttgttgcaaatacaggagaaacccgatcaaatccactaagaaaagagctaggtattggtcgtgataagatgaagcccctt
+atgacacagttagttgaagaagggtggctagagaaagataatgaccctacaaaaggctataagctggttgctaccgaaga
+tatgctcgcagaatggaaagattgagcctgtataggcttattttttttgtccgttaaaccgttatattactaataagcgt
+atcaggaaatatttaacaccgtatttaagacccttgatatgactgtgttcttagctgttttatctaaataactgacacat
+tataatcttaacgtccctctttatatattatttaattatttataaagatatataagagaataataaatataataatacga
+ggagcttaaaccgtataatatgtcaggaatatttttaaaagtacctctaagccagcaataccaacggattaaaatacgtc
+aggtacctctaactctgaaaatttatcaaaatagttgttgacttttagtagtatgtcccgtatacttttgttatgagtta
+cagggatgaatacatgtcctagtgtaggcgatacagtgtagaacgtttgggaggacttctaccgggtatcatccatacta
+acagataatctactgatcttgggagggttcaatggattaactgaactcaggaggtgtaagaatgaactacagagagttat
+cagatgaggaattacttagccagatgtctaccgtacataatgtactagctaacgaagaatgggtttatcgttatgggatg
+aatttaccttaccgattagacaagtttaatagaattttaaactgtttatcttggcaagtagtagctgactcgacttgcga
+taaattaatccggagacaggctaacgaggtacgaatggtaaaacagttaagcacctattaaaaaggagctgcttaacaat
+ggcaattagaaaatatgaattcaaattaaaaattaaacaactattagcggagagaggaatttctcaagctgacctagctg
+aaatgactggattaaggcgtgccactatttcagagatgtctcgtaattcacggtctgttctgaataaggtacatgtagct
+aaagtcatggatgcgttagacgtaactgagttgaatgatatagtggagcttgaggtcactgaggagttctaaaggagaaa
+ataaaatggatagtgtacaaaagtttatttcagaaaatagtcaccaattcggttatatcatgcaagaggctagccgtcaa
+tgggtcgcaaaagaccctatcggagccctaactgtaggtacatgtaagtcttttatagacagctatggagactatcatac
+gattttagacaagttacaagctattgaagaggctaaagtccctaaaaaagatgtgtataaggcagttatctcgggacata
+ttttcgaagaacctgaatttgggaacagtattgaaatatttactttcgtgaataacgacgttaaaaatacagatatattc
+acagatgttgaatatgagctgatcgaagagttaaaacataatcttaaatataaggaaagccacttctttacggctattgt
+gtatgctcgttggtcatcttggcaaagtcaagaaggaactgagtatgatgtagagtacgacatccatgagatcaaacaaa
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+attatgtaaagaaggtagctagtcatcttatcctggtagttaaacgtggggataagcatgagcagatcgtgttagacaaa
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+catcgcagctaagtatacgactacacggttattaacagaaaatctacaaagaattcacgagcatctacaaaagtaaaaac
+ctaaccaaatagtgtataatataactataggataaacaattatttacgattatgtttatcctatttgtttttgtccaaga
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+taaaaacagtatatttgtctacccgaaagttttataaaaagtattgacaggtattggttggtgtagtaaactctaactat
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+taccctgtatcagataaaaagcagtttgaatataagttatgtatgctaaaggacaaggagtacgtatcagtagctgagca
+gcgcatgacagacgaaggctggaagtactacggaaacaaaacgttagagatgagtgtatacagacagttagtagcattta
+tggacaaccgttaatattttagtaggtggttgacttatagcatatgttagccacctatcatactaaaggaggagttagta
+atgcggagaaaaattaagtgtgaattgtgtgatggtagcggtgcctcgccttggtctgctctaggagggccttgtataca
+atgcgagggtgcggggtttctatttgaacctgaagggaagcctaagtttaaggtagacttcggtgagttagacgggctta
+ctaaaatggaagatactacagacttaagtgatccacatattaaaatagatatgaacggcatcagctttaaagacaaggat
+ggtaactggactgatccgacaaaaccattcgctaactttgaaaatatcacaattaaccactcaaatggtaaaactataaa
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+caatcgtaaagcatttgctagtttggagtgttgatgagctactagaccttcacaacgattacaagcagctgtacgatcta
+tttaaggacgaggagtacttgctatatatgaaggacgtactaaaagttataaaagcaaaaacaaattagtagtcattctt
+tatagactgcacgcatagtataaactataacaagaagggaggaattacagtgaatgcggaagataaacgaattctaatga
+aaatagtaggaagtatagccgggatgtttataatgggatacctattcggtttcctaggggttattattagtttagtagct
+atttactttgtgtttaagaatgataatggtaagcaggtaggagaagacccggagagtgaagctaaggccgcctttatctg
+gttctgtgtgatgctagtgttagggatcgtgcttgcgtatctattcggtatcattggagtaattatcggtttagggttaa
+tcgcaggagccatctataatataatgttcgggtaaataaagaattttttttaaatagttgttgactttaaagaaacatgg
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+ctggttactggaataagtataagaaactaaaacagaaaatccttcagtggcagcagcaaa
+=
+> 2:1-61895 + dataset_662722.dat
+gggctctgggcgaagttttgtgggactactatgacttgcattatttcaagcgcaagcggtccgagtggaagtaccaaaga
+tttgctttggtttatcaacaacttgccgacgcggcctcggacacctccatcgcgtccaagtttcagacctacgatcacct
+gccccacctggagccgaaggtgctcaaggcccggcttgacgcgggtcacgccgacgagcgcgggcggccgattccggacc
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+cgacctgctgatccgcgaaatcggtcagttccccgaaggcgcccatgacgaccaagtcgacgccatgacgcagtacctcc
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+gttaacctccgccggggccttaaccctaacacggcgagggttaacaggtccagggacccttcgaaattaacctttcgggg
+accctgggaaatcgtaaggcagggaccctggccattttccggctggggaccctggcaaattcaccgccggggaccctccg
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+cctgttcaagttgcaccgcgatgatctggccgaggcgatcagcttcgagcgggccttgagccccttcgactaggcgcggc
+ctgccgacctaagtcacggactgtaggtttcgtgacaaggtgagatattccacaacgatttcaaaggcttactgcgatgt
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+gccgccgagccctggggcgatttaccaccgccacgttaacctaacgcctgttaacctatcggttgttaaggttaacgccc
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+gggaccgccccggcgctttttcgcgccccgtttaccttttgttaacgtctggcctctagggtcgcccttgtccccgccgc
+actcccgcgccgggcaaggagcttcccgccatggtccccgactcgatcatgaacccccgcgaccacttccaccgcctgcg
+cgaggaaaccgcccgcgctctggtcgaggccttcgccgaatccgaccccggcgaggattaccgcgccgaggaaaaggccg
+gcgcgtgggttgtcgcctattacgacgcggcgggcgaattcgtcgcctatctctagccgccttcgccccctggcgccgcg
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+tatcgccgccatgctcccgcaacgctggcgccacgccttcgcccgcgcgtcgttttggtatgacgcgcacgacaataaaa
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+aggacgccccggaaaatcttccggggcgtttaccttttgttaacctctggcctctagggtgactttcgccgccgggcaat
+cccgcccgccggaccctctttcaaggattgctcccgtcatgacctctcattccatggtcgcgcaccgttgggcgcaggac
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+gcggctacagcgtttcgaccgcgaaacacctttcccacatccgccgcgccatcccgtccgggaccccctgcttttccgtg
+ccgcacgtgtcgcggatgcacaagccgggcgggtcgggcgacttccacggggacaacctgcgcgcctatgtcgagagcgc
+cgccggcctcgccgaaaaggccaagcgcgcccgcgtcaacggcccttggctgcttagccaagcccgcgaaaccctcgccg
+aagcgcaacgctacgccgacgccttcaagctgaaaaccaaggttccggccttggaagacgtcgccggccaatgggcgaag
+atgacggccgccaaggcgcgggccgaagccaaggccaagcgtgacgccgaaaaggccgccaaggcgcgccgcgaagccga
+acggctcgccgacgccgaagccttcgccgcttggatgcgcggcgagcgccagagcgccccgtttagctaccgggtgcgcg
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+=
+> 2:118871-221828 + dataset_662722.dat
+cgacatcggcttcgacgttccgaaggtgttcagcgatccgacgcccgaggaggtcgaggacgccgtgaagctcctgaccg
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+atgtcggcgccagggtcgccctagcccggcgcgtcgccgcgccttcggagaaaaccgccatgctctacacccccgccgcc
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+cggctacaacgagtcggtgtggccgacgacggcgctaggcgtcgccgccaaggccggcgccttcaagcgccccgaaaccg
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+cgcctcatgttctacccctccgccgccatggtcgcggccttcaatgacggcgcggcgtcgtgaaggtcgcccgcgatagc
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+cctctacgactcgcgcggccggtacctgactcaggtctgggcgcacccggttttcagctaggccaggacgccccggaaaa
+tcttccggggcgtttaccttttgttaacctctggcctctagggtgactttcgccgccgggcaatcccgcccgccggaccc
+tctttcaaggattgctcccgtcatgacctctcattccatggtcgcgcaccgttgggcgcaggacgacgagaacggccgca
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+cgcgggccgaagccaaggccaagcgtgacgccgaaaaggccgccaaggcgcgccgcgaagccgaacggctcgccgacgcc
+gaagccttcgccgcttggatgcgcggcgagcgccagagcgccccgtttagctaccgggtgcgcgatgacgggaccgtcta
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+cgcaaggcgcggccgtgccgtgggaacacgcggtcaaggccttccggttcatcaagctttgccgcgaacgcggcgagagc
+ttccaccgcaacggccgggtgattcgcgtcggacacttccaagttgacgcgatcagcccgaacggggacatgacggccgg
+ttgtcaccggttcgcgtgggatgaaatcgaacgcctcgccagggccgaaggggttttcgacctccccgccgacgctggcg
+ccgtcgaaacccggcaagccgaaccggcctaagcctccccgcccctctcgcgccccggctccccgccggggcgttttcgt
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+ccggccccggaaggctacagcgtccagcccctggcgtcgttcctggcctatctggagacggtcggggatagcccttatga
+ccggttccgcgcccatgacgccgccgcccgcatccttgacaccctgacgacgcatctcgccgcctagccccgccaagccc
+ccggccgcgcgccgggggcgctttccctcgaaaggatcgccgaccatgacaacccgtcttatcgccgttcgcggcccgac
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+tgagcgccgcgctcgcgaattcgagcgtcaagcccgcttcttcctgatgatcgccacccgcgcccaaggcgccggccaag
+gccaggaagccgcccgcctcgccacggtcgcacaacgcaaggtgactaactggcgcatggcgcaggcctgcgcccggatt
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+gccgcccgccgcgacgccgaacaagcggcgctagacgccttggaggccgaagccctggccgaagcgccgggcgacgtgat
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+cgacgacgccgacgccttccgggccgaattcgccccgtgggttcacgccgccaacgtgacggccgaaggcgcggccctgg
+cctcgatgatgaacccgaccgccgaagagtatttcagccccgccacgggggtctaacgcccgtggccctgaccttcgccc
+cgcaatcgacgcgctacgccgtggaagtccccgaacgcgactttctggccctgacccgcgccgaggaaattctagcccct
+ggcccctatctggagccgtcgcttagcgagcgtttggaggcgcaagccggcgtttgggatgtcgagtataacggccattt
+cggcgcggccgtttacttgacgctcgacgttgacgccgactccccggccgcccgcgacgccctggcctcgatcatcgccg
+accaactggccaaggccaaggcgtggaagcgccagcccgcctaagtcatcattcctatcgtctatgacttgtcaccggcc
+gaactcttgcccggtgacagtctgggcaagtaaagctcactctggattttatgacttagcgcaaaggattgaaattgctc
+gaaaaattcctcgaagctcacaaagttgttttctggctgcttttgctggcctgtttgtggcgcttttaacggtttgttaa
+cccctggccctctagggtcgaattcccggcgcggcaatcccgccgcccggccttccttcggagcttctgatcatgttcgc
+ttccgtgacccttcccgcccatgacgcccaaggcctgagcctcgaaaccgtccacatggttttcgcccgcgaactggcgc
+aacatttcgaccacgtgatttccgcccccgtggtcgaaagctggcgcgacgaggacaccggcgccgaccacgcgcaagcc
+gccgtttgcttcaccgtctcggcgacccccgccgcgtgggaagccaagggcgggcgcctcgcgcgccggctggaaaacct
+cgccgcgcgctatgccgccgactgcgacgccccggccctgactgtcacccactgcgacggccaaacggtctatgtcggcg
+ctctggaagccctggcgcgccccgccccggtgcaaggcccgacccgtgaggcggacccggctttcctcccccgccagcgt
+gaggacaaggccgcccgcttcgatcgcctgaccgcctagcccctggcctccccctagcgcaccgcccctagaaaggcggt
+gcgcttttctgtgtctgtttacttgttgttaaggaatagcctgctagtgtccccttgttggcggacgcatcccgcgcccg
+cccctttctggatcgctccccatggctcgcccctctgacctgctcaacgtcaacgccgcccgcgtcctggcttgccttga
+gcctatcgccgccgccgctaagaccgccccggccgccgaccgcgccgccctttcctacctgctcgacgctggcgagtatg
+tcgccgcgtggcgccgcaacctcacggaaaccgaccgccgcaaggcctatggcgcggcctgcgccgccgaagccctggcg
+ctcgctaacgcctatcagcccgccaccctgcaaggcggcgccgtccgccgcgctctgggcgcctatgccgccgccctaaa
+ggtcctgctagacggggagccggtcaaggcggtgcgcgccgccgaaggcgcggcgctttcggtccgcgctcgctacgcca
+acacccgcctttaacctcttgttaacacctcccggctatggtcgggaggtcgcaaggagacacccgacatgacccgcccc
+ggccccgcctcgctcctgaccccgcaagcccgcttctcgtcgccgcgcgtcctgatccttccgggcgcggctcccatgcc
+gattcgccagccgcgcggcctttgcgccgtcgagtgcgtcgcccttggcgtgacgctgggcgcggcgctctacctcgccg
+cccgcgtgttcggtctggtctgaccagacccccgccccgcccccggtcggaccggtcgggggtgtgtcccataatgacac
+acccccgccacctagtatcttttttgattcggagggacccaaaggccccctacgttaaccatttttggcggcgccccc
+=
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/test-data/5.xmfa	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,6315 @@
+#FormatVersion Mauve1
+#Sequence1File	dataset_742014.dat
+#Sequence1Entry	1
+#Sequence1Format	FastA
+#Sequence2File	dataset_742014.dat
+#Sequence2Entry	2
+#Sequence2Format	FastA
+#Sequence3File	dataset_742014.dat
+#Sequence3Entry	3
+#Sequence3Format	FastA
+#Sequence4File	dataset_742014.dat
+#Sequence4Entry	4
+#Sequence4Format	FastA
+#BackboneFile	/galaxy/database/files/000/742/dataset_742016.dat.bbcols
+> 1:83043-149557 - dataset_742014.dat
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+---------------------attggtacgattgttgagatgagcacgatatcgaataagac----aagggtagttactt
+cgaatgcactgatagtagaagggagacta--atattggtcatcgtcttagcacccatacccgagatcatatcggatactt
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+-------------------------------------------aacgggacaacaagtaatcgagttaaagactgcctag
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+---------------------------------------------cttttttcttagt--gaccgagggctttttaccct
+cggatggtttactttcactgagtct--agatgttaaatatttatgta---gtttaccagtgaatga-ccccattatacat
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+cgttc-tcgatcgccgacaccatcctcaa---------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
+--------------------------------------------------------------------------------
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+-------------------------------------------gcccctggtcgtcgaccagaccggcggaccgggtttc
+caggcggcgggcgcggcgctccagggcctgaacatcactccgccgggcggcggcggcttcctgtcgggcctgggctcgat
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+gcatc----cagggacacctcctttcatggttaatgcccgatgccgagct-tccacgac---------------------
+--------------------------------------------------------------------------------
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+----------------------------------------------gtcctgttccccgagactatcagctacggctcgt
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+=
+> 1:1-83042 + dataset_742014.dat
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+=
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+=
+> 2:1-61895 + dataset_742014.dat
+gggctctgggcgaagttttgtgggactactatgacttgcattatttcaagcgcaagcggtccgagtggaagtaccaaaga
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+=
+> 2:118871-221828 + dataset_742014.dat
+cgacatcggcttcgacgttccgaaggtgttcagcgatccgacgcccgaggaggtcgaggacgccgtgaagctcctgaccg
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+gcgcttttctgtgtctgtttacttgttgttaaggaatagcctgctagtgtccccttgttggcggacgcatcccgcgcccg
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+ggccccgcctcgctcctgaccccgcaagcccgcttctcgtcgccgcgcgtcctgatccttccgggcgcggctcccatgcc
+gattcgccagccgcgcggcctttgcgccgtcgagtgcgtcgcccttggcgtgacgctgggcgcggcgctctacctcgccg
+cccgcgtgttcggtctggtctgaccagacccccgccccgcccccggtcggaccggtcgggggtgtgtcccataatgacac
+acccccgccacctagtatcttttttgattcggagggacccaaaggccccctacgttaaccatttttggcggcgccccc
+=
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/test-data/karma.fa	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,3699 @@
+>karma
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+ctgacccgcgccgaggaaattctagcccctggcccctatctggagccgtcgcttagcgag
+cgtttggaggcgcaagccggcgtttgggatgtcgagtataacggccatttcggcgcggcc
+gtttacttgacgctcgacgttgacgccgactccccggccgcccgcgacgccctggcctcg
+atcatcgccgaccaactggccaaggccaaggcgtggaagcgccagcccgcctaagtcatc
+attcctatcgtctatgacttgtcaccggccgaactcttgcccggtgacagtctgggcaag
+taaagctcactctggattttatgacttagcgcaaaggattgaaattgctcgaaaaattcc
+tcgaagctcacaaagttgttttctggctgcttttgctggcctgtttgtggcgcttttaac
+ggtttgttaacccctggccctctagggtcgaattcccggcgcggcaatcccgccgcccgg
+ccttccttcggagcttctgatcatgttcgcttccgtgacccttcccgcccatgacgccca
+aggcctgagcctcgaaaccgtccacatggttttcgcccgcgaactggcgcaacatttcga
+ccacgtgatttccgcccccgtggtcgaaagctggcgcgacgaggacaccggcgccgacca
+cgcgcaagccgccgtttgcttcaccgtctcggcgacccccgccgcgtgggaagccaaggg
+cgggcgcctcgcgcgccggctggaaaacctcgccgcgcgctatgccgccgactgcgacgc
+cccggccctgactgtcacccactgcgacggccaaacggtctatgtcggcgctctggaagc
+cctggcgcgccccgccccggtgcaaggcccgacccgtgaggcggacccggctttcctccc
+ccgccagcgtgaggacaaggccgcccgcttcgatcgcctgaccgcctagcccctggcctc
+cccctagcgcaccgcccctagaaaggcggtgcgcttttctgtgtctgtttacttgttgtt
+aaggaatagcctgctagtgtccccttgttggcggacgcatcccgcgcccgcccctttctg
+gatcgctccccatggctcgcccctctgacctgctcaacgtcaacgccgcccgcgtcctgg
+cttgccttgagcctatcgccgccgccgctaagaccgccccggccgccgaccgcgccgccc
+tttcctacctgctcgacgctggcgagtatgtcgccgcgtggcgccgcaacctcacggaaa
+ccgaccgccgcaaggcctatggcgcggcctgcgccgccgaagccctggcgctcgctaacg
+cctatcagcccgccaccctgcaaggcggcgccgtccgccgcgctctgggcgcctatgccg
+ccgccctaaaggtcctgctagacggggagccggtcaaggcggtgcgcgccgccgaaggcg
+cggcgctttcggtccgcgctcgctacgccaacacccgcctttaacctcttgttaacacct
+cccggctatggtcgggaggtcgcaaggagacacccgacatgacccgccccggccccgcct
+cgctcctgaccccgcaagcccgcttctcgtcgccgcgcgtcctgatccttccgggcgcgg
+ctcccatgccgattcgccagccgcgcggcctttgcgccgtcgagtgcgtcgcccttggcg
+tgacgctgggcgcggcgctctacctcgccgcccgcgtgttcggtctggtctgaccagacc
+cccgccccgcccccggtcggaccggtcgggggtgtgtcccataatgacacacccccgcca
+cctagtatcttttttgattcggagggacccaaaggccccctacgttaaccatttttggcg
+gcgccccc
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/test-data/merged.fa	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,6360 @@
+>phagey
+tggtattacaagagagaaaggaagtaatcgatatgcaacagacagcagctaagaacacac
+aaccagaaggtttacatctttacatggcaattggatcgtatgagtcggccattaacaaat
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+tatacaacagaggatacagaaaaggttcggatgacgcggccactattatactagatcgca
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+gaagagaggaagtataacagtgtagacgaaatggtgaaagacttgaatggtgtactttat
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+gaccagacacacttcgatgttgaagactggggagtgtacgaggatgaaaagacgggtaac
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+cggcgctttcggtccgcgctcgctacgccaacacccgcctttaacctcttgttaacacct
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+cgctcctgaccccgcaagcccgcttctcgtcgccgcgcgtcctgatccttccgggcgcgg
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+cccgccccgcccccggtcggaccggtcgggggtgtgtcccataatgacacacccccgcca
+cctagtatcttttttgattcggagggacccaaaggccccctacgttaaccatttttggcg
+gcgccccc
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/cpt_progressivemauve/test-data/phagey.fa	Fri Jun 10 08:41:20 2022 +0000
@@ -0,0 +1,2661 @@
+>phagey
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+ggagggccttgtatacaatgcgagggtgcggggtttctatttgaacctgaagggaagcct
+aagtttaaggtagacttcggtgagttagacgggcttactaaaatggaagatactacagac
+ttaagtgatccacatattaaaatagatatgaacggcatcagctttaaagacaaggatggt
+aactggactgatccgacaaaaccattcgctaactttgaaaatatcacaattaaccactca
+aatggtaaaactataaaaggcgggaaaggggttctgaaaccgatgggattattcgatgat
+tttatggaggctattgaagcagaagagacaggaagaccaatcgtaaagcatttgctagtt
+tggagtgttgatgagctactagaccttcacaacgattacaagcagctgtacgatctattt
+aaggacgaggagtacttgctatatatgaaggacgtactaaaagttataaaagcaaaaaca
+aattagtagtcattctttatagactgcacgcatagtataaactataacaagaagggagga
+attacagtgaatgcggaagataaacgaattctaatgaaaatagtaggaagtatagccggg
+atgtttataatgggatacctattcggtttcctaggggttattattagtttagtagctatt
+tactttgtgtttaagaatgataatggtaagcaggtaggagaagacccggagagtgaagct
+aaggccgcctttatctggttctgtgtgatgctagtgttagggatcgtgcttgcgtatcta
+ttcggtatcattggagtaattatcggtttagggttaatcgcaggagccatctataatata
+atgttcgggtaaataaagaattttttttaaatagttgttgactttaaagaaacatggtgc
+tagaattagcttatcaaccaaaggaggtaacaaagtgagaataacacatgaacagaagat
+ggaaattctcgaagagtggaaccttataggagagaacgattgtagaacggctctacctca
+cttaacagagctacttactaaaatacttgatagtgtttctgatcctgaaaagataaactg
+tgggtgttatgtgtggagtgaaaaactacaagagcatgttgaacctaatccactctgtaa
+gaaatgcggcgggatgggttggtattacaagagagaaaggaagtaatcgatatgcaacag
+acagcagctaagaacacacaaccagaaggtttacatctttacatggcaattggatcgtat
+gagtcggccattaacaaatatgcgcacccatataatcctggttactggaataagtataag
+aaactaaaacagaaaatccttcagtggcagcagcaaa
+
+