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date Fri, 21 Apr 2023 10:04:39 +0000
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<p class=MsoNormalCxSpFirst style='margin-bottom:0in;margin-bottom:.0001pt;
text-align:justify;line-height:normal'><b><u><span style='font-size:12.0pt;
font-family:"Times New Roman","serif"'>CDR3 characteristics tab</span></u></b></p>

<p class=MsoNormalCxSpMiddle style='margin-bottom:0in;margin-bottom:.0001pt;
text-align:justify;line-height:normal'><span lang=EN-GB style='font-size:12.0pt;
font-family:"Times New Roman","serif"'>This tab gives information on the
different characteristics of the CDR3.</span></p>

<p class=MsoNormalCxSpMiddle style='margin-bottom:0in;margin-bottom:.0001pt;
text-align:justify;line-height:normal'><b><span lang=EN-GB style='font-size:
12.0pt;font-family:"Times New Roman","serif"'>Graphs</span></b></p>

<p class=MsoNoSpacing style='margin-bottom:0in;margin-bottom:.0001pt;
text-align:justify;line-height:normal'><u><span style='font-size:12.0pt;
font-family:"Times New Roman","serif"'>length distribution of CDR3</span></u></p>

<p class=MsoNoSpacing style='margin-bottom:0in;margin-bottom:.0001pt;
text-align:justify;line-height:normal'><span style='font-size:12.0pt;
font-family:"Times New Roman","serif"'>Graph visualizing for each donor the
distribution of the CDR3 length in amino acids between all sequences.</span></p>

<p class=MsoNormalCxSpMiddle style='margin-bottom:0in;margin-bottom:.0001pt;
text-align:justify;line-height:normal'><u><span style='font-size:12.0pt;
font-family:"Times New Roman","serif"'>Amino acid composition of CDR3</span></u></p>

<p class=MsoNoSpacing style='margin-bottom:0in;margin-bottom:.0001pt;
text-align:justify;line-height:normal'><span lang=EN-GB style='font-size:12.0pt;
font-family:"Times New Roman","serif"'>Bar graph visualizing for each donor how
frequent each amino acid is used in the CDR3 of all sequences. The red colour
in the background indicate positively charged amino acids, and the blue colour
in the background indicate negatively charged amino acids. The amino acids are
ordered from hydrophilic (left) to hydrophobic (right). </span></p>

<p class=MsoNormalCxSpMiddle style='margin-bottom:0in;margin-bottom:.0001pt;
text-align:justify;line-height:normal'><b><span lang=EN-GB style='font-size:
12.0pt;font-family:"Times New Roman","serif"'>Table</span></b></p>

<p class=MsoNoSpacing style='margin-bottom:0in;margin-bottom:.0001pt;
text-align:justify;line-height:normal'><span lang=EN-GB style='font-size:12.0pt;
font-family:"Times New Roman","serif"'>Table showing for each donor the median
CDR3 length.</span></p>

<p class=MsoNormal><span lang=EN-GB>&nbsp;</span></p>

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