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author | dcouvin |
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date | Mon, 10 Jan 2022 20:06:07 +0000 |
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#Gene_ID Gene_name Codon_pos Ref_nuc Ref_codon Res_codon Resistance PMID Mechanism Notes Required_mut gyrA gyrA 70 GCC A T Nalidixic acid, Ciprofloxacin 8384814 Target modification gyrA gyrA 85 GAT D Y Nalidixic acid, Ciprofloxacin 18031331 Target modification Phenotype described only in association with other mutations (T86), unknown phenotype if the present mutation occurs alone gyrA_T86I.A.K.V gyrA gyrA 86 ACA T I,A,K,V Nalidixic acid, Ciprofloxacin 11266291,Unpublished,8384814,16713726 Target modification gyrA gyrA 90 GAT D A,N,T Nalidixic acid, Ciprofloxacin 8384814,8384814,16713726 Target modification gyrA gyrA 104 CCA P S Nalidixic acid, Ciprofloxacin 16713726 Target modification Phenotype described only in association with other mutations (R285), unknown phenotype if the present mutation occurs alone gyrA_R285K 23S 23S 2074 A A G,T,C Azithromycin, Erythromycin, Clindamycin, Telithromycin 16713726,16713726,16713726 Target modification 23S 23S 2075 A A G Azithromycin, Erythromycin, Clindamycin, Telithromycin 16713726 Target modification rpsL rpsL 43 AAA K R Streptomycin 20370506 Target modification rpsL rpsL 88 AAA K R,E,Q Streptomycin 20370506 Target modification