Mercurial > repos > galaxyp > metagene_annotator
changeset 0:b04960a7abf5 draft
planemo upload for repository https://github.com/galaxyproteomics/tools-galaxyp/tree/master/metagene_annotator commit 6d8b6e0fa2f1b47b337dbf21f5bc320586ccbd4c
| author | galaxyp |
|---|---|
| date | Wed, 21 Mar 2018 17:15:25 -0400 |
| parents | |
| children | 17c7ab82bfbc |
| files | convert_mga.py metagene_annotator.xml static/images/Sixgill_MetaGeneAnnotator_Workflow.png test-data/m_mga.bed test-data/m_mga.tsv test-data/m_mga.txt test-data/metasequences.fasta test-data/metasequences1.fasta test-data/metasequences2.fasta test-data/s_mga.bed test-data/s_mga.tsv test-data/s_mga.txt |
| diffstat | 12 files changed, 604 insertions(+), 0 deletions(-) [+] |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/convert_mga.py Wed Mar 21 17:15:25 2018 -0400 @@ -0,0 +1,91 @@ +#!/usr/bin/env python + +from __future__ import print_function + +import argparse +import math +import re +import sys + + +def __main__(): + parser = argparse.ArgumentParser( + description='Convert mga output to bed and tsv') + parser.add_argument( + 'input_mga', + help="mga output to convert, '-' for stdin") + parser.add_argument( + '-t', '--tsv', default=None, + help='Path to output mga.tsv') + parser.add_argument( + '-b', '--bed', default=None, + help='Path to output mga.bed') + parser.add_argument('-v', '--verbose', action='store_true', help='Verbose') + args = parser.parse_args() + + input_rdr = open(args.input_mga, 'r')\ + if args.input_mga != '-' else sys.stdin + + bed_wtr = open(args.bed, 'w') if args.bed is not None else None + tsv_wtr = open(args.tsv, 'w') if args.bed is not None else None + if tsv_wtr: + tsv_wtr.write('#%s\n' % '\t'.join([ + 'seq_id', 'seq_model', 'seq_gc', 'seq_rbs', + 'gene ID', 'start pos', 'end pos', 'strand', 'frame', + 'complete/partial', 'gene score', 'used model', + 'rbs start', 'rbs end', 'rbs score'])) + + gc_rbs_pat = '# gc = (-?[0-9]*[.]?[0-9]+), rbs = (-?[0-9]*[.]?[0-9]+)' + seq_count = 0 + gene_count = 0 + for i, line in enumerate(input_rdr): + # 1317/1 + # gc = 0.272955, rbs = -1 + # self: - + if line.startswith('# gc'): + try: + m = re.match(gc_rbs_pat, line.strip()) + seq_gc, seq_rbs = m.groups() + except: + seq_gc = seq_rbs = '' + elif line.startswith('# self:'): + seq_type = re.sub('# self:', '', line.rstrip()) + elif line.startswith('# '): + seq_name = re.sub('# (\S+).*$', '\\1', line.rstrip()) + seq_count += 1 + else: + fields = line.split('\t') + if len(fields) == 11: + gene_count += 1 + start = int(fields[1]) - 1 + end = int(fields[2]) + if tsv_wtr: + tsv_wtr.write('%s\t%s\t%s\t%s\t%s' % ( + seq_name, + seq_type, + seq_gc, + seq_rbs, + line)) + if bed_wtr: + bed_wtr.write( + '%s\t%d\t%d\t%s\t%s\t%s\t%d\t%d\t%s\t%s\t%s\t%s\n' % ( + seq_name, + start, + end, + '%s:%s' % (seq_name, fields[0]), + int(math.ceil(float(fields[6]))), + fields[3], + start, + end, + 0, + 1, + abs(end - start), + 0)) + + if args.verbose: + print("sequences: %d\tgenes: %d" + % (seq_count, gene_count), file=sys.stdout) + + +if __name__ == "__main__": + __main__()
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/metagene_annotator.xml Wed Mar 21 17:15:25 2018 -0400 @@ -0,0 +1,186 @@ +<tool id="metagene_annotator" name="MetaGeneAnnotator" version="1.0.0"> + <description>gene-finding program for prokaryote and phage (used by sixgill)</description> + <requirements> + <requirement type="package">metagene_annotator</requirement> + <requirement type="package">python</requirement> + </requirements> + <command detect_errors="exit_code"><![CDATA[ + #set $output_list = str($output_formats).split(',') + touch mga_output + #for $input in $inputs: + && mga ${input} $multiple_species >> mga_output + #end for + #if 'tsv' in $output_list or 'bed' in $output_list: + && python '$__tool_directory__/convert_mga.py' mga_output -v + #if 'tsv' in $output_list + --tsv '$mga_tsv' + #end if + #if 'bed' in $output_list + --bed '$mga_bed' + #end if + #end if + ]]></command> + <inputs> + <param name="inputs" type="data" format="fasta" multiple="true" label="prokaryote DNA sequences"/> + <param name="multiple_species" type="boolean" truevalue="-m" falsevalue="-s" checked="true" + label="MetaGenomic - Sequences are from multiple organisms" /> + <param name="output_formats" type="select" multiple="true" display="checkboxes" label="output formats"> + <option value="txt" selected="true">MetaGeneAnnotator text report</option> + <option value="tsv">MetaGeneAnnotator tabular report with sequence columns</option> + <option value="bed">MetaGeneAnnotator in BED format</option> + </param> + </inputs> + <outputs> + <data name="mga_txt" format="txt" from_work_dir="mga_output" label="${tool.name} on ${on_string} metagenefile"> + <filter>'txt' in output_formats</filter> + </data> + <data name="mga_tsv" format="tabular" label="${tool.name} on ${on_string} mga table"> + <filter>'tsv' in output_formats</filter> + <actions> + <action name="column_names" type="metadata" + default="seq_ID,seq_model,seq_gc,seq_rbs,gene ID,start pos,end pos,strand,frame,complete/partial,gene score,used model,rbs start,rbs end,rbs score"/> + </actions> + </data> + <data name="mga_bed" format="bed" label="${tool.name} on ${on_string} mga bed"> + <filter>'bed' in output_formats</filter> + <actions> + <action name="column_names" type="metadata" + default="chrom,chromStart,chromEnd,name,score,strand,thickStart,thickEnd,itemRgb,blockCount,blockSizes,blockStarts"/> + </actions> + </data> + </outputs> + <tests> + <test> + <param name="inputs" value="metasequences.fasta" ftype="fasta"/> + <param name="multiple_species" value="True"/> + <param name="output_formats" value="txt"/> + <output name="mga_txt"> + <assert_contents> + <has_text_matching expression="# 1/1\s# gc = 0.275862, rbs = -1\s# self: -" /> + <has_text_matching expression="gene_1\t1812\t1994\t-\t0\t11\t14.10\d+\tb\t2002\t2007\t2.11\d+" /> + </assert_contents> + </output> + </test> + <test> + <param name="inputs" value="metasequences.fasta" ftype="fasta"/> + <param name="multiple_species" value="False"/> + <param name="output_formats" value="txt"/> + <output name="mga_txt"> + <assert_contents> + <has_text_matching expression="# 1/1\s# gc = 0.275862, rbs = 0.428571\s# self: b" /> + <has_text_matching expression="gene_1\t1812\t1994\t-\t0\t11\t12.48\d+\tb\t2002\t2007\t0.49\d+" /> + </assert_contents> + </output> + </test> + <!-- Try these later + <test> + <param name="inputs" value="metasequences1.fasta,metasequences2.fasta" ftype="fasta"/> + <param name="multiple_species" value="True"/> + <param name="output_formats" value="txt"/> + <output name="mga_txt"> + <assert_contents> + <has_text_matching expression="# 1/1.*# 10/1" /> + <has_text_matching expression="gene_1\t1812\t1994\t-\t0\t11\t14.10\d+\tb\t2002\t2007\t2.11\d+" /> + </assert_contents> + </output> + </test> + <test> + <param name="inputs" value="metasequences.fasta" ftype="fasta"/> + <param name="multiple_species" value="True"/> + <param name="output_formats" value="txt,tsv,bed"/> + <output name="mga_txt"> + <assert_contents> + <has_text_matching expression="# 1/1\s# gc = 0.275862, rbs = -1\s# self: -" /> + <has_text_matching expression="gene_1\t1812\t1994\t-\t0\t11\t14.10\d+\tb\t2002\t2007\t2.11\d+" /> + </assert_contents> + </output> + <output name="mga_tsv"> + <assert_contents> + <has_text_matching expression="#seq_id\tseq_model\tseq_gc\tseq_rbs" /> + <has_text_matching expression="1/1\t-\t0.27\d+\t-1\tgene_1\t1812\t1994\t-\t0\t11\t14.1035\tb\t2002\t2007\t2.11\d+" /> + </assert_contents> + </output> + <output name="mga_bed"> + <assert_contents> + <has_text_matching expression="1/1\t1811\t1994\t1/1:gene_1\t15\t-\t1811\t1994\t0\t1\t183\t0" /> + </assert_contents> + </output> + </test> + --> + </tests> + <help><![CDATA[ +**MetaGeneAnnotator (mga)** + +A gene-finding program for prokaryote and phage. + +The gene annotations can be used by sixgill_ when generating metapeptides from metagenomics shotgun sequencing. + +.. image:: Sixgill_MetaGeneAnnotator_Workflow.png + :height: 213 + :width: 625 + +usage: + mga [multi-fasta] <-m/-s> + + -m (multiple species sequences are individually treated) + -s (single species sequences are treated as a unit) + +**Input:** + *A fasta file of metagenomic sequences* + + +**Outputs:** + + *MetaGeneAnnotator text report* + Output from the MetaGeneAnnotator mga application:: + + # 1/1 + # gc = 0.275862, rbs = -1 + # self: - + gene_1 1812 1994 - 0 11 14.1035 b 2002 2007 2.11797 + # 2/1 + # gc = 0.338877, rbs = -1 + # self: - + gene_1 1 414 + 0 01 25.748 b . . . + gene_2 614 790 + 0 11 0.774142 b . . . + gene_3 822 1079 + 0 11 20.6507 b . . . + + output format description:: + + # [sequence name] + # gc = [gc%], rbs = [rbs%] + # self: [(b)acteria/(a)rchaea/(p)hage/unused(-)] + [gene ID] [start pos.] [end pos.] [strand] [frame] [complete/partial] [gene score] [used model] [rbs start] [rbs end] [rbs score] + + explanations of output column: + *The value of [frame] (0/1/2) indicates the number of surplus (untranslated) nucleotides at the 5'-end of the predicted ORF. + *The value of [score] indicates the estimated score of predicted gene. All predicted genes are more than 0. + *The value of [complete/partial] indicates that the predicted gene structure is whether complete (contains both of start and stop codons[11]) or partial (lacks start[01] or stop[10] or both of them[00]). + *The value of [model] indicates a selected model ((s)elf/(b)acteria/(a)rchaea/(p)hage) for predicting the gene. + + + *MetaGeneAnnotator tabular report with sequence columns* + The mga output reformated as a tabular file:: + + #seq_id seq_model seq_gc seq_rbs gene ID start pos end pos strand frame complete/partial gene score used model rbs start rbs end rbs score + 1/1 - 0.275862 -1 gene_1 1812 1994 - 0 11 14.1035 b 2002 2007 2.11797 + 2/1 - 0.338877 -1 gene_1 1 414 + 0 01 25.748 b . . . + 2/1 - 0.338877 -1 gene_2 614 790 + 0 11 0.774142 b . . . + 2/1 - 0.338877 -1 gene_3 822 1079 + 0 11 20.6507 b . . . + + + *MetaGeneAnnotator in BED format* + The mga output reformatted as a BED file which can be used to extract the DNA sequences for each gene from the fasta file:: + + 1/1 1811 1994 1/1:gene_1 15 - 1811 1994 0 1 183 0 + 2/1 0 414 2/1:gene_1 26 + 0 414 0 1 414 0 + 2/1 613 790 2/1:gene_2 1 + 613 790 0 1 177 0 + 2/1 821 1079 2/1:gene_3 21 + 821 1079 0 1 258 0 + + +.. _sixgill: https://github.com/dhmay/sixgill + ]]></help> + <citations> + <citation type="doi">10.1093/dnares/dsn027</citation> + </citations> +</tool>
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/m_mga.bed Wed Mar 21 17:15:25 2018 -0400 @@ -0,0 +1,40 @@ +1/1 1811 1994 1/1:gene_1 15 - 1811 1994 0 1 183 0 +2/1 0 414 2/1:gene_1 26 + 0 414 0 1 414 0 +2/1 613 790 2/1:gene_2 1 + 613 790 0 1 177 0 +2/1 821 1079 2/1:gene_3 21 + 821 1079 0 1 258 0 +2/1 1960 2140 2/1:gene_4 11 + 1960 2140 0 1 180 0 +2/1 2327 2405 2/1:gene_5 3 - 2327 2405 0 1 78 0 +3/1 61 220 3/1:gene_1 3 + 61 220 0 1 159 0 +3/1 559 754 3/1:gene_2 30 + 559 754 0 1 195 0 +3/1 1238 1403 3/1:gene_3 4 + 1238 1403 0 1 165 0 +3/1 1581 1798 3/1:gene_4 14 - 1581 1798 0 1 217 0 +4/1 2 431 4/1:gene_1 9 - 2 431 0 1 429 0 +4/1 581 743 4/1:gene_2 8 + 581 743 0 1 162 0 +4/1 1458 1746 4/1:gene_3 17 + 1458 1746 0 1 288 0 +4/1 2281 2372 4/1:gene_4 5 - 2281 2372 0 1 91 0 +5/1 0 191 5/1:gene_1 25 + 0 191 0 1 191 0 +5/1 397 619 5/1:gene_2 14 + 397 619 0 1 222 0 +5/1 780 1143 5/1:gene_3 27 + 780 1143 0 1 363 0 +5/1 1163 1412 5/1:gene_4 10 + 1163 1412 0 1 249 0 +5/1 1811 1871 5/1:gene_5 4 - 1811 1871 0 1 60 0 +6/1 149 344 6/1:gene_1 4 - 149 344 0 1 195 0 +6/1 401 791 6/1:gene_2 16 - 401 791 0 1 390 0 +6/1 768 945 6/1:gene_3 2 - 768 945 0 1 177 0 +6/1 1626 1941 6/1:gene_4 31 - 1626 1941 0 1 315 0 +7/1 0 330 7/1:gene_1 33 - 0 330 0 1 330 0 +7/1 358 997 7/1:gene_2 47 - 358 997 0 1 639 0 +7/1 1076 1349 7/1:gene_3 30 - 1076 1349 0 1 273 0 +7/1 1481 1703 7/1:gene_4 12 - 1481 1703 0 1 222 0 +7/1 1747 1857 7/1:gene_5 2 - 1747 1857 0 1 110 0 +8/1 0 193 8/1:gene_1 5 + 0 193 0 1 193 0 +8/1 589 745 8/1:gene_2 12 + 589 745 0 1 156 0 +8/1 1821 1903 8/1:gene_3 4 + 1821 1903 0 1 82 0 +9/1 117 543 9/1:gene_1 5 - 117 543 0 1 426 0 +9/1 622 901 9/1:gene_2 9 - 622 901 0 1 279 0 +9/1 946 1105 9/1:gene_3 5 - 946 1105 0 1 159 0 +9/1 1313 1505 9/1:gene_4 9 - 1313 1505 0 1 192 0 +9/1 1548 1727 9/1:gene_5 9 - 1548 1727 0 1 179 0 +10/1 0 66 10/1:gene_1 4 - 0 66 0 1 66 0 +10/1 256 715 10/1:gene_2 44 - 256 715 0 1 459 0 +10/1 1136 1310 10/1:gene_3 6 - 1136 1310 0 1 174 0 +10/1 1626 1824 10/1:gene_4 10 - 1626 1824 0 1 198 0
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/m_mga.tsv Wed Mar 21 17:15:25 2018 -0400 @@ -0,0 +1,41 @@ +#seq_id seq_model seq_gc seq_rbs gene ID start pos end pos strand frame complete/partial gene score used model rbs start rbs end rbs score +1/1 - 0.275862 -1 gene_1 1812 1994 - 0 11 14.1035 b 2002 2007 2.11797 +2/1 - 0.338877 -1 gene_1 1 414 + 0 01 25.748 b . . . +2/1 - 0.338877 -1 gene_2 614 790 + 0 11 0.774142 b . . . +2/1 - 0.338877 -1 gene_3 822 1079 + 0 11 20.6507 b . . . +2/1 - 0.338877 -1 gene_4 1961 2140 + 0 11 10.3813 b . . . +2/1 - 0.338877 -1 gene_5 2328 2405 - 0 01 2.71033 b . . . +3/1 - 0.269188 -1 gene_1 62 220 + 0 11 2.43434 p 52 57 0.162572 +3/1 - 0.269188 -1 gene_2 560 754 + 0 11 29.2723 p . . . +3/1 - 0.269188 -1 gene_3 1239 1403 + 0 11 3.28908 p . . . +3/1 - 0.269188 -1 gene_4 1582 1798 - 1 01 13.4314 p . . . +4/1 - 0.550169 -1 gene_1 3 431 - 0 11 8.00428 p 440 445 -0.537592 +4/1 - 0.550169 -1 gene_2 582 743 + 0 11 7.07558 p 569 574 -2.00256 +4/1 - 0.550169 -1 gene_3 1459 1746 + 0 11 16.2536 p . . . +4/1 - 0.550169 -1 gene_4 2282 2372 - 1 01 4.40418 p . . . +5/1 - 0.256547 -1 gene_1 1 191 + 2 01 24.4289 b . . . +5/1 - 0.256547 -1 gene_2 398 619 + 0 11 13.8688 b . . . +5/1 - 0.256547 -1 gene_3 781 1143 + 0 11 26.4034 b . . . +5/1 - 0.256547 -1 gene_4 1164 1412 + 0 11 9.28281 b 1152 1157 -2.19822 +5/1 - 0.256547 -1 gene_5 1812 1871 - 0 01 3.07971 b . . . +6/1 - 0.329727 -1 gene_1 150 344 - 0 11 3.09009 b . . . +6/1 - 0.329727 -1 gene_2 402 791 - 0 11 15.7382 b . . . +6/1 - 0.329727 -1 gene_3 769 945 - 0 11 1.97601 b 952 957 -2.75668 +6/1 - 0.329727 -1 gene_4 1627 1941 - 0 01 30.867 b . . . +7/1 - 0.316101 -1 gene_1 1 330 - 0 10 32.7357 b . . . +7/1 - 0.316101 -1 gene_2 359 997 - 0 11 46.468 b . . . +7/1 - 0.316101 -1 gene_3 1077 1349 - 0 11 29.3212 b 1355 1360 -1.77606 +7/1 - 0.316101 -1 gene_4 1482 1703 - 0 11 11.6788 b 1716 1721 0.607519 +7/1 - 0.316101 -1 gene_5 1748 1857 - 2 01 1.33924 b . . . +8/1 - 0.35155 -1 gene_1 1 193 + 1 01 4.66209 b . . . +8/1 - 0.35155 -1 gene_2 590 745 + 0 11 11.9555 b . . . +8/1 - 0.35155 -1 gene_3 1822 1903 + 0 10 3.61015 b . . . +9/1 - 0.57209 -1 gene_1 118 543 - 0 11 4.22762 p . . . +9/1 - 0.57209 -1 gene_2 623 901 - 0 11 8.51219 p . . . +9/1 - 0.57209 -1 gene_3 947 1105 - 0 11 4.01029 p . . . +9/1 - 0.57209 -1 gene_4 1314 1505 - 0 11 8.25466 p . . . +9/1 - 0.57209 -1 gene_5 1549 1727 - 2 01 8.49456 p . . . +10/1 - 0.314145 -1 gene_1 1 66 - 0 10 3.31418 b 80 85 -0.655414 +10/1 - 0.314145 -1 gene_2 257 715 - 0 11 43.0773 b 722 727 -2.59179 +10/1 - 0.314145 -1 gene_3 1137 1310 - 0 11 5.91709 b 1322 1327 -2.35659 +10/1 - 0.314145 -1 gene_4 1627 1824 - 0 01 9.87622 b . . .
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/m_mga.txt Wed Mar 21 17:15:25 2018 -0400 @@ -0,0 +1,70 @@ +# 1/1 +# gc = 0.275862, rbs = -1 +# self: - +gene_1 1812 1994 - 0 11 14.1035 b 2002 2007 2.11797 +# 2/1 +# gc = 0.338877, rbs = -1 +# self: - +gene_1 1 414 + 0 01 25.748 b . . . +gene_2 614 790 + 0 11 0.774142 b . . . +gene_3 822 1079 + 0 11 20.6507 b . . . +gene_4 1961 2140 + 0 11 10.3813 b . . . +gene_5 2328 2405 - 0 01 2.71033 b . . . +# 3/1 +# gc = 0.269188, rbs = -1 +# self: - +gene_1 62 220 + 0 11 2.43434 p 52 57 0.162572 +gene_2 560 754 + 0 11 29.2723 p . . . +gene_3 1239 1403 + 0 11 3.28908 p . . . +gene_4 1582 1798 - 1 01 13.4314 p . . . +# 4/1 +# gc = 0.550169, rbs = -1 +# self: - +gene_1 3 431 - 0 11 8.00428 p 440 445 -0.537592 +gene_2 582 743 + 0 11 7.07558 p 569 574 -2.00256 +gene_3 1459 1746 + 0 11 16.2536 p . . . +gene_4 2282 2372 - 1 01 4.40418 p . . . +# 5/1 +# gc = 0.256547, rbs = -1 +# self: - +gene_1 1 191 + 2 01 24.4289 b . . . +gene_2 398 619 + 0 11 13.8688 b . . . +gene_3 781 1143 + 0 11 26.4034 b . . . +gene_4 1164 1412 + 0 11 9.28281 b 1152 1157 -2.19822 +gene_5 1812 1871 - 0 01 3.07971 b . . . +# 6/1 +# gc = 0.329727, rbs = -1 +# self: - +gene_1 150 344 - 0 11 3.09009 b . . . +gene_2 402 791 - 0 11 15.7382 b . . . +gene_3 769 945 - 0 11 1.97601 b 952 957 -2.75668 +gene_4 1627 1941 - 0 01 30.867 b . . . +# 7/1 +# gc = 0.316101, rbs = -1 +# self: - +gene_1 1 330 - 0 10 32.7357 b . . . +gene_2 359 997 - 0 11 46.468 b . . . +gene_3 1077 1349 - 0 11 29.3212 b 1355 1360 -1.77606 +gene_4 1482 1703 - 0 11 11.6788 b 1716 1721 0.607519 +gene_5 1748 1857 - 2 01 1.33924 b . . . +# 8/1 +# gc = 0.35155, rbs = -1 +# self: - +gene_1 1 193 + 1 01 4.66209 b . . . +gene_2 590 745 + 0 11 11.9555 b . . . +gene_3 1822 1903 + 0 10 3.61015 b . . . +# 9/1 +# gc = 0.57209, rbs = -1 +# self: - +gene_1 118 543 - 0 11 4.22762 p . . . +gene_2 623 901 - 0 11 8.51219 p . . . +gene_3 947 1105 - 0 11 4.01029 p . . . +gene_4 1314 1505 - 0 11 8.25466 p . . . +gene_5 1549 1727 - 2 01 8.49456 p . . . +# 10/1 +# gc = 0.314145, rbs = -1 +# self: - +gene_1 1 66 - 0 10 3.31418 b 80 85 -0.655414 +gene_2 257 715 - 0 11 43.0773 b 722 727 -2.59179 +gene_3 1137 1310 - 0 11 5.91709 b 1322 1327 -2.35659 +gene_4 1627 1824 - 0 01 9.87622 b . . .
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/metasequences.fasta Wed Mar 21 17:15:25 2018 -0400 @@ -0,0 +1,20 @@ +>1/1 +CTGGGAATGGGTGTCTTGAGATAATTTCTTTATTCAATTAAGCTCTAAACCTAAATTTCTTACTTCATCTTTAAATAAGAATTTAAGAGGTTCGACTAATTTTAATCTCATTTTTTTTGGTAATCCGCCTACATTATGATGAGATTTGATTTTTGACGTTTGGCTTCCTGTTACTGATCTGCTTTCAATAAGATCTGGATAAAGAGTTCCTTGAGCTAAAAATTTTACATTCTTAATTTTTTTTGCATATCTTTCAAAATTTTAATAATAAATTTCCAATTATTTTTCTTTTCTTTCTGGATCTGAAACGTTTGTTAACTTTTTTAAAAATTCTTTTTCAGCATTAACGTATATTAAATTCATCTTTAGCCTTTCTTAAAAGTATTAACTACTTGTTTTCCTCATTTTTCTAAGAAGACCAGTGTTAACAAAAATACAATATAGCTTTTTACCATAGCTTTATTTAATAATGAGCACTACACTACTATCAACTCCTCCTGAAAGGGCACAAATAACTTATTTTCACCAACTTGATTTCTAACCTCTTTAATTAATTTCATCTTTTGATCTTTTGATGACCAGTTTTTTTAATTTTAATATTAAGGAAATAAAATTTTTAATAATTTTTTACCATTTTCTGTATGTGGTAACTTCAGGATGAAACTGAACACCATAAAATTTATTTGTATTGTCTCCAACAATTGCCAAATTTTGAATTTTGACTTGATGCAATTACTCCTAAAATTTTAGGTAATTTTGAAACTTGATTCAGCATGACTCATCCATACTTTATGAATTTTTTTTTGATTAAAGAAATTTTTTAATTAAAAGACTATCTTTTTTTTATAGACATTAGCTAAACCAAACTCCCGATGCTTTGATTGTTTGACCTTTCCACCATTTAATTTTGACAAGATTTGGTGACCAAACAAATTCCTAATATTGGTATATTGTTTTTAAGTATTTCTTTATCAAGAAATATCTATTAATTTCATAAACGTTAAGGGGACCTCCTGATAAAATGATACCTTTAATTACTTGTATCAATATTTTTATTTTTAATCTTTTTATGACTAATAATTTCTGAGAATACCCTAGTTCTCTTATTCTTCTGGCAATCAATTGTGTAAATTGAGACCAAATCTATGATTAATATTTTATTTAAACTTTGATCAAGAATCATTTTTTGGCTCTATATTCGCTAGAGTCTCCAAAATATCTTTATTTATCATCACATAGTTTTTTACAAACTTTTGTAAATGTTATTTTGATAGATCTTTTACTTTTGAATAATTTGATTTTCTAAAGCAATTTTCATTAACATTAATATTGGCTTCTTCGTTATCAGGTTCGATTAATAATGTTGTTTCTAAATTTTTTTCTTTCTTTTTTTGATCCTCTTCAAAATTATAATCTTTGCCAAGTACAAATATGAATTTGAGTCTTTAGGATTAAAAACATACTTCTTTCAACATAAATCTTGCATCGTCATATTTTTCTGTCTTTAAAAAGTTCTAAGCCTTTATCAAAAAAAATTCTCATTACCAAAAGATGTTGCTTGCTAAATTTATGAAAAATAAATTAATACAGTTTTTTTTAATTTTATCATCATTATCAATCATCATCTTTTTACTATATCAACGTTATGTACCATACTTTCGTAAATCCAGCTTTTGTAATCTTTACAAATTTTGGTTTATTTCTTAAATATTTAATTGTGTCTTAGAACCAGATAACCATCGACGATTTCAAACCGACCAATAAGTTGGAAAATTATTTTTCAACCTTACTTTTATATTTAGCAAATCCTTCTACACCTTCAGGTACATATTTGAGATATCTTTTTGTTTTGATTGAAAATATCTATCAGCTGAACCTTTATTCATAGCACCCCACTGATCCATACCTCTAAAACTTTTAATAACTTTCCCACCTCTTCTAATTAATTTACCTGGGGTCTCATCGGTGCCTGCAAATAAATGAACCACCATCACTGCATCTGCTCCTGCATCAAAAGCTTTGGCTAAATCACCAGTGTATTTAATGCCTCCATCAGAGATAAGATCTTAACATTTTTATTTTTAACTCGTTTCTTAACTGTTAAAATTGCACTTAACTGAGGAACTCCAATACCTGCCACTAATCGTGTGGATACAGATAGACCCAGGGCCTATACCCACTTTAATTATATCTACCCCTAATTTTAAAAAATGTTGCAGCTTCTGGTGGTAGCTATTATTACATGCACACTAAAGCTGTCTTTTATTTTTCTTTTTTTAATGAATTTAATTATCTCTGAAACTTTTTGTATGACCATGGG +>2/1 +GCAAGATCTGATTTATTATTGCCAGAATCACAATATGAATTCTTTAAAGTTAAGTTAGAACAAACAAGCATCATTTCACCATTTAATGGAGTTATACAGAATAGGTTTTTAGATACAGGTACAGTAATTAACTCAGGGATCCCTATACTTGAGATCATTGATTCGAATTATGTTGAAGCACATATTTCTGTACCTGTTATCTATTTAGAAGATATGCAAATCAATGAAGAATATAATTTTGAGTTTGATGGTGAGATAACAAAAGCAACTTTCGCCAAGCTAGCACCAATGTCTCCGGGCGTTCAAATAGTAGACTGGCGATATTTAAGTTTAGTAAATTTTTTAATCCAGGCCTCAATAGCAAACCTCCAATTAAAAATTTCCAACAAGCAAAAGGTACCTGGGTTCCTTTAAAGTCTCTAATCTCAATCAGATCAGGGCTTATGGACAATATATACAATCGACAATAGCAATACTGTTGTTAGAGATATAGTAGAAATAGTCCATTTTGAAGATGATTATGCATTCGTTAGTGGCACCATAAAAAATGGTGATTTAGTTGTCTTAGGCGGAGCATCTAAGATTATTGAAGGCAAAAACTTAATTAGAAGAAATGAAATTTATAAGTATATTTCTTGATAGACCAAGAATACTCTTTTTAACTTTAGCTTTCATATTACTTTCTGGCATTTCTTCAATATATACATTACCAATTCAAGAGAATCCAGAGTTAGCTGAGAGATGGGCGACTGTTACCATTTCATATCCTGGAGCCGCACAGAGAGAATAGAAACACAAGTTGTAGATATCTTGAAAATAAATTGAGAGAAATTGTTGAGCTTGATATCGAAGATTTAGCGTCAGTAATTACTCAAGGCTTTTCTGAAACACTAGTAGAATTGCAACAAAGTGTTCCACCCTCATTAATAGAAGAAGTTTGGTCAAAAGTTCAAAATAAAATTGATCAAATAGAAACACCTGATGGAGTAACCATGTTGCTTGAAAGATCATCAGGACCACCTATAACTGTTGAGTACATTATTGATTGGAGGGTGAAGGAAATGCGCCAATTATTATGATGTCCAGATTGGCACAACAACTACAGAAAAGTTGAGTTCTGTTCCAGGGACAGAAAAGACAGCTATATATGGGAGAGGCAGAAGAAGAAATAGTTGTTGAAGTTGATTCTGCAAAAATGTCATCCCTAGGATTAACATATCAAGAAATCAAGTTCAGCCATAAGATCATATGACAATAAAAAACCTGTTGGGGTGGTCTCTGATGAATATTCTGAATTTTTAATACGATTAAAAGATAACATAACGAGTCCTCAAAAGATTGGCGAAATACCAGTTAACGGTAATAAATCAATCCGAAATTATAAGGCTTCAAGATATAGCCGAGGTCTCGATGCAACCCGCTAATCCAATCGAAGACATATTTTTATACAATGGTCGAAGAGTTTTATCGGTATCTGCTACAGGATCATTTTCACAGAGGTATTTGAGTATGTAGAAAATGTAGATGTTCAAGTCGATAAAATGCGATTAACATTACCTGAAGAATTCCAAATTGAAAGAATATACGATGAGTCGATATATGTATCCAGTAAATTTGGAGAACTAATTAAAAGCTTTGCATTAGCAACTTTTTTTTGTATTAAGTCTAAGCTTCTTTTTCTTAGGAATTAGGCCAGGAATAATAGTAACCGCTATTTTGCCACTTTCAGTATCTTTGGTTTTGCTTGGTTGCAGATTAATAGATTTACCCCTTCACCAAACATCATCACCGGAATAATTATTGCCTTGGGGCCTCCTAATTGATAATGGAATCATAGTTGTTGAAGATTATAAATATAGAAGATCAATTGGACTTTCAATTAGAGAGTCTATAAATCAAACATTAGTTCACATATCAACACCTTTGTTGGCTGCAACAGCAAACTACTGTTTTTGCGTTCATGCCTATAGTAACTGGGGAAGGATCTAGTATTGAATTTGTAGGCGGTATGGCGTTAACCGTAATAATGTCAATTATTTCATCATTAGTATTAGCATTGATTATGGTTCCTGTTTTGATGAGTTACATGGAACGCATACCTTATTTTGCAATATACAATGTTCATGAAGAGGCGATATAAAATGAGAAGATTCTAAAAAAATATAGAAAATTCTCTACCTGGGCTTTGATTATACCGACGACGAGCCATATTGATTTCAATTTCTTTGCCACTTATTAGGGTTCTTTGATATTTGGTTCTATTCCAAAGACTTCTTTCCTGCAAATGATAGAGATATGTTTCGAATTCATATAGAGCTTCAACAAATTCATGCTTCAACAAAGACACTTGAAAGAGCTTCAGGAAACTTAGACAACAGGTAATTGATAGCAATCTTTGATAGAAT +>3/1 +TTGATCGATACAAAAATAAACAAGATTTTATTCAAAAATATATCTTTTCCCCGGAGGGTTTTTGCCCAATAAAAATACTATCAATAAACTAGTTTCTAAAAATGGACTAACTGTTAATTCATATATTTCATATGCCGGATCATTATGCAGATACACTTGGCGATTTGGAAAAAAGAATTTTAATAAAAAGTGGGATATGATTAAAAAACCAAGGTTTTGATTTTAACCTTTAAGAGAATGTGGGAATTTTATCTATCTTATTGTGAGGCTGGATTTAAATCAAAAAATATTGATTTAATTCAATTTTCGGTTTCAAAACAAATAATGAATATATTGGAGTTTTTTAGATGCGTCATATAAAAATTGTTAACTCTATTTTATTGATAATTTCACTCTTCTTAATTACAAGTTGTTCAAACAACAATTGCAATGAAACCTGGAAGATTTTAAAAACAAAGAACCAAGACTTATAATAGAGGAGTATTTAACAGGAAATGTTAAGGCTTGGGGTGTTTTACAAAATCGTTCAGGAAAAGTTACCAGACAATTTTCAGCAGATTTGGATGGATCATGGGACGGCAAACAATTAATTTTAAAAGAAAAATTTAATTGGGATGATGGCGAAGTTCAAAATAGAGTATGGACTATCACTAAAATTGATGAAAATAATTATGAAGGTACAGCTGGAGATGTTGTTGGTAAAGCAATAGGTATTCTTATGGACCAGCATTTAAATTTGAGTATGTTTTATTAGTTCCTGTTAAAGGTAAAGAAATGAAAATTACTTTTGGATGATTGGATTTTTAAACAAGATGAAAGAGTTGCTATAAAATCGAGCGACAATGACTAAATTTGGTTTTAAGGTAGCAGAATTAACAGTCGTATTTTGTAAAAGATTAAATTTTTTCTTTATTGTGTTTTTATAGCTAACAATAATCATTCTCAAAAAAAATGTGAGATTGATTATCATTCGCCAATAATCTTGTTGTTTCTTCATTAAAAAAAAAATATTATTAAATAATGGAAACACAAAACTATAGTTGTAAAAAATGTGGACTTACAGTTTCATCTATATGCTCTAAATGTGATAGAGTTGTAGATGTAAAAGTTCTTGATAACGGTTGTATTGTTCAAAAGACAAAATGTAATGATTTGTGCAAATGTACCTGTTATTAAAGATGTTTGTTCACAAAGTTAAAAATAATTAAAAAGAAGTCTATTTATCCTATAAACCAAAAATGGAAGTTACAACAGGTATATTCAAAGCAGCCGAAAATATATTTAGAAATAATAAGGGTTCGATATTAAGAACTATTGTTTATACTATTGGTCATTTTGCTATTGCCAATAACTGTTCTTATGTTAGTTGCCTGATGTATCCATTTTGTTATAGCTTTAACTGATGCAATTATAGAGCCTCTAGCTAATTCATTTGGTATTTCATCTTGATAAATGGTGGATTAGCAAAAATCTTAATAAAAATTAATTTTTTTTTTGATATTTTGTAAGTTTACTTAGTAAACCCAAAATAAATACTACTAGGTTAAAAAGCTCAAGAATTTTAAGATTAAAGTGAGTGTCTTAGGAAAAATGTATCTCAAAATTGTTTTTATTAATTAATCCATCATAAATTTTATCTGCAGCATACTCAGAAGTCTTTAAAAATGGCATTTTAAAATCATTTTTATCGGTCATTGGCGTTTTAATAAAACCAGGTGAAACCAAACAAATACGGACATTAAATCTTTTAAAATCAAAATATAAACTTTCAGCTAAATTATTTTTAATGCTGACTTTG +>4/1 +CATCAGCTTTGATGGTCCGCTCTTCCACACCCTTGGCACCATCGACCACCATCAGCGCCAGAGTCGACCGCGGTGAGCACCCGGTAGGTATCCTCCGAAAAGTCTTCATGGCCCGGCGTGTCTAGCAGATTGACCACCCGATCCTTGTATGGGAACTGCATCACGGAAGAAGTCACCGAAATCCCCCGCTGCTGCTCCATGGCCATCCAGTCAGAGGTCGCGTGACGGTCTGATTTCTTGCCTTTGACTGTTCCGGCCACCTGAATCAGATTGCCGAACAGCAACAATTTTTCAGTGATGGTGGTTTTGCCGGCATCAGGGTGAGAAATGATGGCCAGTACTCGCCGGCGATCAATTTCGCGCTGTAATGATGCTGTTGGTGACACGACAAACTCGCAGTGGCTGCAAGATAGACTGTAACGCGGCCGCATTATAGCAGCTGCTTACATTCGCCACATCAGCTCCGGGCACCGGATCGGCAGATGTCAGCGGCCTTCGGCTCAGAGCCGCCATGCATTACAATGAGTTGGCAAGACGAGACCGCACCAGATTGCCCATCCATTACCAGAACGGACCAGATCATGAATTTTACCCTGACAGAACAACAACGCGCCCTCCAGCAAGCGGTCAGAAAATTTGCGCAACAGGAGCTGCCGGACATTGCTCGACAAATTGAGGTTAACGATGAACCAGTGGATCTCGCCCTGCGCCGTCGCTATGGCGAACTCGGCTATCTCGGGTGAATCTCGACAGCTCGGTCGGCGGTGGTGGCATGAGGTCATCTCGACGCCGTGATCGTGCTGGAGGAAGTTGCGAAGATTTCAATTGCGGTGGCGTTTCCGATCTTCGAAGCCTGTTTTGGCCCCAGTTTGGCCATCGCCCACTTCGGCAGCGAATCACTCAGGCAGCGTTATCTGCCCCAGGTCTGTACCGGGGAAAAAGTGGGTGGCGGTGTCCATGTCAGAGCCGGGCGCCGGATCTGCACTGGACTGATCTCATCACCCGGGGAGAAATCACCGGAGACAGAATTATCCTCAACGGAAACGAAACGATGGTGCTCAGGCGCCGGACATTCGGAAGCTTATGTTGGTGTACTGCCGACTCTCGGATGCTCCGGGCGCCAGGGGCATCGGAGCTGTGGTGGTGGACAAAGGCACCGACGGCTTCAGTTTCGGCAAGCGGTGACCACCATATGGGGCTTCAGAGGCGTTTACAGTTGCGACATGTATTTCGACAATGGTCGAAGTGCCGCTGGAAAACAATGCTCGTTACCGGCCCGGCAGTTTCGGCAAGCTGATGGATGCCTTCGACCTGGAACGCCTGCGGTAACACGACCATGTCACTTGCGGGTGGCGCAGTCCGCATTTGACTACGTGCTGAACTACAGCCAGGAACGTGGAGCAATTCGGTAAACCACTGGTAAGAATTTTCAGGCGATACAGATACAGCTTGCCCGAAATGAAGATGAAGCTTGAAGCTGCGCGTCTGCTGCTTTACCGCGCAGTGGTCAATGCCGAATCGGGCCTGCCGTCACTTGGCGAAAGCTCGGTTGCCAAATGCTTCGCCAATGAGGCTGTCCGGGAAGTGACGGGTAAAGCGATGCAGATCATGGGCGGGTATGGCTATTCCAAGGAATTTCCTATCGAGCAAAAGCTCCGTGACGCCTGGGGCTGGGGTAATTGCAGGGGGATCAATCGATATCCAGAAAGTGATATTACCTCTGCACTGGTAAAACCGACGCTTTAATCAGCGAGCCAACTGAGCGATCTAGTGCAGGGGTCGACCCGTCGGACGACATCGGCGCTCGGCGAAATCCGGGTGCAGTTATCGATCTGTTTGACCAACAAGAGATCGTGACGAGAGAGATGATCATGTTCAATGTCTGAACGAACACTCGACGTCTTCCAGCATCACGCAGACGACATCATCATCGTCAATATCGACGACGATGCAGGATTTAAATCCGTCTACCGTATTGATCGAGGCCAGCGAACCCACATCGAACTGATAAATCGGCAAAGAACCGCTGGCACGCTGTAGCAATCCATAGGAAAGTAAACGCGACCCCGAAGCCTGCCGCCGCGACCACGTTAATAATTTCCACCACTTCCGGATCGGTCAGATCACCCGAACGGTCTCGGCAAGTGGCTGATTCACCTCTAACTGCCGTCGATTAATCAACCTCAGAAACAGATCAATGTCTCCTGATTCCATTCGAGCGTTTCTTCCGAGACAGATCGGGTGCTGTCTGAGGACAGGCTCTGCACGTCAGTTTCGATAGTCAGATCCCGAACTTTAGTGTCCGGCGGACCAAGGCACTACCATTGAGACGGAACCAGTAGCCGTCGCTACGCTCTGCGCTGAGGCGCCAG +>5/1 +TTTTAGATGATACAGACGAAAATTTTTCAGGAAAGTTAAAAAAATTTAATTTAATTGGAATTCCATATCAAATTCTAATTGGAAAAAATCCTGATAAAAATAAAGTTGAGTTTAAAGAAGTGGGGAACGATAGTAAGATGATAAGTCTTGAAGAAGCCCTTAATTTCATTAAATCCAAAAAAATAAATTGATTTCAACTTTAGAAAAAAAAATAATTTTTAGATATCTTAAAACTAGAAAAAAAGATGGTTTTTTAAACATCATCACTTTATTCATTCTTAGGCATAAGTTTAGGCGTGGCAGTTTTAATTATAGTTATGTCTGTAATGAATGGATTTAGGTCAGAGGCTGATAAACAAGATAACTAATTTCAACGCACATGTAATCGTGAAACCCTATGAAAAAAAATAGAACAAAAAAAATAGGTAACGAGTTTTTACAAAATATATCTTCAAATTTGATATTAAGTAATAATGGAGAGGGAATACTTTTAAATGATGAAATTACTAAAGGTATTTTAGTTAGAGGCTATTCTGAAAATGACTTTCAAAAACTAAATATTGTAAATAATAAATATTTTAGAGGTAATAAAAAGATTTTAAAGACAATATATCGATAGGGAGCGATTTAAGTTATGACCTTGAATTAAAAATTGGTGACCAGATTTCAATAATTTCACCTTCTGGTGAAAATACACTTATTGGATCTATACCTCGACAAAAAACTTTTAAAATTGATTCTATATTTGATAGTAGGTTTGCTGAGTTTAATAGTTCTGTTGTGTTTATTAATCTTAAAGATCTACAAGGTTTGTTTGATTTAAAAAAAGAAAATAATTTCTTAGAGGTTTATTTATATAAACCTGACAAAATTGAGATTTATCGTGAAAAACTGTTGTCGATTTTTACTGACGAATATATATTTACTTGGTCAGATCTAAACAAACCATTATTTTCTGCTTTAAAAGTAGAGAGAAATGTTATGTTTATAATATTATCCTTAATAATTATAGTCGCTGCTTTTAACATTATTTCGGGTCTTACTATTTTAGTAAAAAATAAAACTAGGGAAATTGCTATATTAAAATCAATAGGTGTTTCTAACTTTTCCATTCGAAAAATATTTTTTTTATTGGATTTTTAATAGGATTTTTAGCAACAATTATGGGAGTTGTTATAGGCGTAACTTTTTCTCTTTATGTTGAGGAAATTAGAATGCTAATTAGCAATGTCTTTAATATAAGTTTATTTCCAGAGGAAATATATTTTTTAAGCACGATACCATATCAGATAGATTTTTGGTCAATATTTTTGATTTCAAGTTGTTCAATTATAATGACCTGTTTAGTCTCAATATACCCTGCAACTAAAGCAGCAAAATTAGATACAATTAAATCATTAAAATATGAATAACATTATAGAACTAAATAATATTTCAAAGATATTTAATAATCAAAAAAGACCACTGTTCTTAAAAATTTAAATTCAAATTCAAAAAAGGAAAAATTTATTCATTATCAGGGCCTTCAGGATCTGGAAAATCCACATTACTCAATTTATTATCTTTAATAGATAGACCATCATCCGGAAATATCAAAATTGATAGTCAAAATATAAATCACAACGAAATTGAGATTAATGATAAAATTAGATCTAATAATATTGGAATTGGCTATCAAGAGAAAAATTTACTAACTGATTTTACAGCTATCGAAAATGTTTGCTTAGCTAGCTTAGCTGCTAATAACAATCAGAAAATAGCAGAAAAAGAATCATTAAAAATTATTCAAAAAGTTGGCTTAAAAGATAGGACTAATCATTACCATCAGAACTATCAGGAGGAGAGTTGCAAAGAATTGCTTCTATCGAGAG +>6/1 +CATATCAAAATAATCATCGCCTTTTTCAGATATGTTAAGGTTAGTTATATTGCCACCTGCACTTCCAACAATGGTTGCTAATTTACCTAAAGATCCAGGTTCATTTTTAACTGAGACTTTTATTCTTGACGAAAAATACTGCTTTGGATCTACATCTTTCCATGAGGCAGTGATCCAATCTTCTTTTTTGTTTCTTTATCTAGCTCCTTACATAAACTGGAGTGAATGATTACACCTGAATCTTCTGATGTAAGTCCCAAAATATTTTCATTGGGTAAAGGGAAACAGCATTCTGCATAATGAATTGCGATTCCAGGTTGGAAGTTACTTATCTCTAAAGGCATCTTATCGTTTGTGTCTCTCTTCTGTATCGAGAAAAAAATGATAAAGTTGAACGGGGCTTAAGCTTTGATAATTGATGTGGCCTTTATACTTCCTTTACCAATTGCAACAAGAAACTCCTCAGGACTTTTCCTATTAAAAATTTTTGCAAAATTACTAATTTCTGTGTTTGAAATATCTTCATTTCTACCTGTGACTTTGTGTAATATTTTTAACCCTAGACTTGTAAATTCATCTTTTTCTTGCTTTTTAAAAAATCTTTTTATCGATGACTGCGCCTTTGCAGTTGTAACAATATTTTCCCAAGTTTCAGATGGAGATGGTTTTTTTGATGTTAGTACTTCAATCTCATCTCCATTTTGAAGTTTTGTAAATAAGGGTCTAGGTTTTCCATTAATCTTACATCCAACGCAACGATTTCCAATTTCAGAATGAAGGGCATAAAGCAAAATCGATAGAGTTAGAATTTGCAGGCAAATGAATTAAGTCACCTTTCGGTGTAAAACAAAAAACTTGATCCTGAAACATTTCTAATTTTGTAGCTTCAAGTAAGTCCTCAGAGCTTCCACCGCTGTCCAATATTTCTACTAATCTCTCAACCAAAGTAACATTAACTGGATCTGAAGAAGAGTTATCTACTAAATTATAATTCTCTTTATAGCTCCAGTGTGCCGCTATACCCTTATCTGCTATTAGTGTTCATTTCATTTGTTCGAATTTGAAGTTCAACTCTCTGTCTTTCAGGGCCAACAATTGTTGTATGAATTGACTGATAATTATTAATTTTTGGTGTCGATATATAATCCTTAAATGAGCCTGGTACAGCAGACCACCGGTTATGAATGATGCCAATATACTATAACAATCTTCAATGCTATTAGTGATAATCCTATAAGCAAAAAATATCCGACAATTGTCTAAAAGCAATTTGGCTTATTCTGCATTTTATTCCATACAGAGAAGATTTTTTTTTTTCACGTCCTATTATTTGACAATCAATTTCATTTTTTTCTAAAAGACTAAAGAATCCTTGTCTTTATTTTATCAGTTAAATTAGATTTATCTTTCTTTAAATACTCAATTCTTGTCATCAATGAGGAATATGCAGATGGATTTAAAATTTGAAATGATAAATCTTCCAACTCGTCCTTGAATTCATGCATCCCCAATCTTCCAGCAAGGGGGCATAAATTTCTAATGTTTCCGATGCAATACGTTGTCGTCTTTTTTCCTGTGGAATAAATTGAATCGTTCTCATGTTGTGTAAACGGTCAGCTAACTTTACTAACAAAACTCTTGATATCCTTCGACATTGCTAAAATTAATTTTTCTGAAATTTTCAGCCTGGAATTTATTTTCAGTATACGTTTCAATTTTTGACAGTTTTGTAACGCCGTTTACTAATTGAAGGACTTCTTTTCCAAATTTTTCTTCAATTTCATTTTCTGTAGCAAGAGTATCCTCAAGTGTGTCATGTAAAAGGCCCGTTATAATTGTGGAAGTATCTAACTTTAAGTTTAATAGAATATCTGCAACTGCAACTGGGTGAGATATATAAGGATCACCTGAATGCCTTTTTGTGACTTGTGACACTCGACT +>7/1 +TAAACTATAAATACCTTTTGTATATTTTTTGTAAGTCTCGTAAGAATTTGATCCAACAGCAGCTTGTAAAAGATGAATTAATTTTCCTTGGTATTGGTGTGTTTCACCATTTTTTCTGTATCTATAAATTCCACCTATAGGTAAAATATCTGAGTGAACATCAAAAGCATCTTTATGAATAGCTCTAATTTTTTTTTCAATACCAGTTAAACCAATTCCTGAAATTTTTGAAACTACCCCTGGAAAATAATCTTTAACAATTGTTCTGCTTAAACCAACAGTTTCAAAGTTGCACCCACCTCTGTAAGAGCTAAGTACTGAAATTCCCATCTCGACATTATTTTTAACAAACCAAGATTTACTGATTTAATATATCTAGCAACGCACTCATCATAGGAAAAATTGCCAAAAGTTTTTTGGAATGTCTTTGATATAAACTATCAAATGCAAGGTATGGATTTACTGTTGTGGCACCGACACCTATAAGAGTAGCAAAAGAATGTGTATCAAGAGCATCTCCTGTTTGAACATTAATAGAAACATATCCCCTTAAGCCTAATTTTATTAAATGAGTATTTATTGCACCAATACATAAAAGCATTGGCATAGGAAGTTTTGTTTCAGATGTTTTTTTATCAGATAGAATAAGTTGAGTAACACCTTCTCTAACTGCTTTTTCAGCATCTTTTCTCAATCTTTCAATTGACTCTTCAAGGGTTTGATCATCATTGAATGTACACTCTATAGTTTTATAGTTATCACCAAAGTATTTTACGAATTTGTCAAATTGGGTATTTGATAGAATTGGACTATCTAATACATAAATATTTTCTTCAGTAAGATTTGAAAAATCAAGGATATTTCCAAGATTTCCAAATCTAGTTTTAAGACTCATTACTTTATTTTCTCTTAACGAGTCGATAGGAGGATTGGTTACTTGACTAAAATTTTGTCTAAAAAGTGGTAAAGAGGCTATATTTATCTGATAATACAGCAAGTGGTGTATCATCACCCATCGAGCCAGTTGCCTCTTTTGCATCTTCTGCCATTGGATGCCAAGATTAATTCCAAATCCTCTAGACTATATCCAAAGCAATGTTGTATCTTTTTAAATCAGTTCCAGAAAACTCATTTTTTTCATTTTCAATAGTCAAAGTCTTATCCAAATCAATAATTTGATTATTAAAGTGCTTATATTCCTTGGCTAAATAATTTTTAATTTCTTTATTTGAGTAAACTTTTCCTTTTTCAATTCTAACGCCTAATATTTCCCCTGGTCCTAATCTTCCTTTTGAAACAATTTTTTTTTCATTTAGGTCAATCATTCCAGTTTCAGACCCAGCAAACAATAGTTTATCTCTTGTTACCGTATATCTAAAGGTCTAAGTCCATTTCTATCGCTTGCCACAATTACCCATTCATTATCTGTTGCTGCTATAGCTGCAGGACCATCCCATGGTTCCATAGTGCTATTCAAAAAGTTAATAATTGTTGATGATCTCGTGAAAGAACTTTACTTTTTTTAGACCAAGCATCGGAATTAGTATTAATTTTGCTAATGGTGCTGAATGACCAGAAATATTTAAGAGTTCAAAGACATTATCTAACGAAGCAGAATCCGAATTACCCGCTGGAATTACAGGTTTTAAATTTTCCATATCTTCAAATAGAGGACTAAACATTTCTTCTTCATGAATTCTCATCCAATTAATATTTCCTTTTAAAGTATTTATTTCTCCATTGTGTGCTATTGACCTAAATGGTTGAGCCAAGTCCCAACTGGGAGCTGTGTTAGTTGAAAACCTTTGATGAAAATTGCGTATCTTGATATAAAACGTTCATCTTTTAAGTCCTGTA +>8/1 +CTTTTATGGTTTAAACGGTAAAGCAAGTATTATTAACGGACCCGTAGTTGCCTTTGAAGTAACTCAGCAAGGTTCTAACGGACTATATCTACTTTATTTAATGGCTGTTTATTTAGGAGTTTTGCAGTTACGATGTTGCTGCAATTCACAAGTTATTTTTATGAGCAGTAGCCACAAACTTCTGCAAAATTGATGAAGAGGTAAATATTTCAAAGGTCGATAAAACAAAAATAAAGTTTAGTATCGAAAATATGGAAAGCCAATAATGGAATTATTTTTTTTAGCTATATTAGTTTTAATTATGATTGCAGCTCTAGCTTCAGGGTATCCAGTTGCCTTTGCTCTTCCTGGTTCAAGCTATCATATCTAATCGGTTTAGCAGCTTTTTTTGGTTATATTTTTTGCTGGCGATGTTGATGCTTACTTCGCTGTCGATGGTCCAACCGAATGGCTTGTTGCTGGAATTACAAAATTTTAGAAGTAATTACTGGGACGTCGAGACTGACACTTTAATTGCAATTCCCTTATTTATTTTTATGGGAATTATGCTTCAAAAAATCAAAAAATTGCTGAGGATTTATTAATAACTATGGGTCCAATTATTTGGCCCCCGATACCTGGTGGTTTAGGTATTTCGGTAATATTTGTTGGTGCATTATTAGCTGCAACTACAGGTATTGTCGGAGCAACAGTCATTGCAATGGGATTAATTTCATTACCTACAATGTTTAAACAACAATTATGACAGAAAACTTGCAAGTGGAATTGTTTGCTCTTCTGGAACTCTAGGACAGATTATTCCGCCATCAATTGTATTAATTATTATAGCGGACCAATTAGGCGAGGCGCATCAGATGTTGCCAATAACATGAGGCAGAACGATTATAAAGCTTTAACAGCGCGAATTTAACATGCCAGGTGAATTTAGAGTAGGTTTCATCCAGTGCCGGTGACATGTTCCTGGGAGCACTTTTACCAGGGAATGTAGTACTTGTAGCTTTATATATGATCTATGTATTGTTTCTATGCGAAGAATAAAAAAAGGGGTTGCCCCACCTGTTCCATTAAAGGAAACTTGATTTCAAATTTTGGATGAAAGTTATTGTTTTAATTATTCCTCCACTTGCATTAATTTTTGCTGTTTTAGGATCGATTCTTATGTGGTATTGCAAGCTGTGAACCAAGCTGGTTCTAATAGGAGCAATTGGAGCAACATTAATGGCGGGTTACCGTCTATTTCAGGTAAGAAAAGTGCCTCTTCTATCACTTATAATGATAATTGGATCATTAATACCCATTACATTTCTTTTTTGCATCAAATTATGACTTAACATAAAAAATATAGAAGAAGAGATTTAGGAGCAATTTATATAACTGCTATTTTTGTAATCACTTGGTTTATGGCAATAGCATGGAGTTTTTGGAGAACATATAAAACTGAAAATGCTTCTTAAAGAAGCAGTAACCGAAACGTGCGTTACAACTTCGATGGTATTTATTATTCTATTTAGGTGCTGCAATGCTTACATCAGGATTTAGAGCATATTGGTGGTGAAGAATAGTAAGAGACTTCCTTCAAGATTTACCCGGGGGCTTGGACTCAGTTTGTAGTTGTAATGATTGTAATATTCTTACTTGGGTTCTTTTTAGAATTTTATTGAAATCGCTGTTGTGGTTGTTCCAATAATTGCACCTATATTATTAGCTGAGACAGGAGCAAACCGTTACCAGCGGTCTGGTTATGGTGTTATGATTGGTGTCATATTTACAAACCCTCTTTTTTAACTCCCCCCTTTGGTTTTGCCTTATTTTATTTAGAAAATGGTGTTGGTAAAAGTGGTACAAACATTAGATATTTGGAAAGGTGTTGTTCCATTTATAATTTTACAACTCATTGGCCTAG +>9/1 +AAGAAGGCTATCCATTCGGCGGGCCGCCTCGCCAAGCGCCGACGAGCGCCGCAATTCATCAACCAGCGTTCGAGCCGTCGGGAGACCCGCTGGCGTACCAGCTGTCAAAATCGGCCCTCATCCCGGCACCAAGCGACTGACGGAACAGTACGACAACGCCGTTCGGTGCGCGCCGTCCAAGATCAGAGCCACAGGTGTTGGCCCCGTCAGCACCAGAGAAATTGAGAATGTCATTGGCAATCTGATAGGCATTCCCGAGCGCCCGGAAACAATCACCGATGGTCGGGCCGCGCCGCCATGAAGCGCCATCGCCGCGACGCCCTCAAGCGGGGCTGTTAGCAGCGGAGCTGTCTTGTCGCCAGCCCCCTGAAGATAATGGTCCCAGTCCTTGACCGGCCGGACGTCGAATTCCCGTGCTTCGCCGATCGTCGTCGTCTTCATGTGCGTTGCCAGGATTTTCACCAGCATCGGTGTCTGTGATCGCTGCGCCGCCTCAGCGGCGAGTTCGAATGACAGGGCGACCAGCCAGTCACCAAGGGTCAACGCGACATCGCGGCCATAGACCGACAGACAGCCGGACGGCCGCGGCGCAGACGGTCACCATCACAGATGTCGTCATGGATCAGCGAGGCGTTGTGAAGCACCTCGATGGCCACCGCCCAGTGAAGGCCGCCGTCCTGTCGACTTTCAGGAAGTCGGCGGCGCGAAGGGCCATCTTGGCGCGCAGCATCTTGCCAGGGGCGGCGAAATGGTGAAGCGCCGCATCGGCCAGCGGCTGACCAGGCTGCGGCATGCGCTCGATAACGAATTCATGGATGATTTCCGAAATGACTGCGAAACCGGAACTCCCCGTACCGGAGTCGGAGAAGATCTCGTTCACTGGGGTGGACAGGTCAGTCATGCTTACCGTGCTTCAACTATTCCACGAGTGTAGCACGTAGTAATTTCAATATATTATGTGAACACGGGCGACGATTTGGTGCCGCCCCGTTTCTCTTGATTTGTTATGCTTCTTTGCTGTCGCGTTGGCGGCTGCCCAGATTACACCGACGAAGGCGATCTTATTAACAACGTCAGCGACGTTGTAGATCACATTCAATGTCACCGCGTCAGCAGCGCCATTTAGGTAACCGAGGAAGTAGCCTAGTGGGTAGATCGCCCAGCCAACGTAACGATTAACCGCATCGTACCGAAAGACTTCTGGACGGCCTCCGGAGCGGACTCCGCAGATACCCTTCCTGCTTCACCGGCAAAAATCTCATACAAGATGTATGCCCATCCCGCCATGCCAACGACAAAGCCAAGCCAAGCGTTCACGAGACCTGCTTCGCCGAGGTAACCAGCGACAGCATTACCAGCGACCCAATCATCAGGCGCCAAAAAATGCCAGCGCTGACAACTGCGACTGCCGCTAGAATGAAGTAGAATTCAACCATTTGGAGAGGCACGGTTATTAGCCAGTCAACATACCTGTAAACTGTTGGCGTCTCACCTGTGCTGCCCATACGTCGCGCATGTAAAAGTAATGAACTGCCGCAACGATCTGCACTAGGCACCGATCGTCATAGCAGTCTTCCATTTGCCTGGCAGGCGAGCGGCTTCCATCAGGAAGAAAATTGCCGCGGCCATCATCGCCATTGAAATGGTCCAGAAAGATATGCCCACAAAGTCGGTAGCGGCAAGCATTGTCGTTTCTGCATTTGCGACTGATGGGAGAATGGCAAGTC +>10/1 +AAACTCAACAAACTTAGCGTTGTGCTTTTTATGTAGTTCGTATAGTGCAGTTTTTTTTATATTCATATTAACTCTCTAACCCCCTCTGTCGTGGTGCCTGAGAGATTTTAGCTCCTTCGGCGAGAATTTGTCTCTTTCCAGAGTTAATATGTACGGTCCTTTTGCCTGAGAGTTTCCGGGGTGGTTGCTCCTTCGGCGCTACTCAATGTAGTCTCTCCCGTATAAAATTATATTAGCATATTTTTGACAATCGTCATCAAGAAATAGTTTTTTTTTCTAGTTTAATAACATTGTAAAACTGTAGTAATACTGCGAATAATACAATTGACCCCCCAATTAAAACAACAAATGGTGGATTTTCACTCACAAATAACCATGCCCAAAGAGGTCCAAGAATAGCTTCAGTGAGCATTATGATACCAACAATTGCCGAGGGCGTAGATCTTGCTCCAATTGTTATAAAAATAAAACCAAAACCTAATTGAAAAAAACCTGCTAGAAAACCTAAAAATATATCATATGAAGAAATATTAATTTTACCTGCAACCAAATAACCAACAGACATTGCAACTATTCCAGCAATTAATTGTAACGGTATCATGTCTACATCTGGATATTTTCTAATAATAATAATTAAGATTGCAAATGACACAGGCATAATAAATGCTGCAATATTTCCAGACATTTGTCCTGGAGACAAAGATCCCCCAACCATTAAAATAATACCAGAGATAGCTAGTATAATTGATATTAAAGTTAATTTTGAAATTTTTCTTTTAAAAATAAATATCCAAAGATTGCAAAAAATTGTTTGAGTTTGAATAATAAATTAGCATTGGCTACTGTTGTATTATACATTGCAAAACATAGCCACAAAACCCTGAAGATAAAACTATACCACCGATAAGACCGGGAAAGCCTGATTTCTTAAATGCATGAAAAAACATTTTTTTTATAAGTAACGAGTAAAAAATTGATACAACTAAAATAAAAAAAGAGATCTCCAAAAAAGTATCTGCCATAATGTGGCGCCCTCGAAAGATTTTACAATCATCCTCCAAAACTTAAACTAGTGGCACCAAAAAAACTAAAAGTGGACCCGGTAATCTTGTATAAAATTCATCTTATTTTATTAATTATATTCTTAGTTTCCATAGTATAAATTTTGTATAAATTTTCTGCCTCGTAAGACTTATAATTTTGAATTTAATTTTTTCTCCAGGTGGGCATTGTGCTAACTTGTCATAATCTGCACTTATTACAACAGCAATTTTTGGATAACCACCTATTGTTCCATGATCTGAAAGCATTACTATAGGGTCTCCGTCAGCTGGAACTTGTATTACTCCTTTTCCTAATCCTTCAGACTTGATGTTTGTTTTCTTAAATTCTTAATTTTAGGTCCACTTAATCTCATTCCCATCCTATCGGTAAGTTTTGAGACAATAAATCTTTACTTGTGAAATCTTTGATTGAGTCTTCTGAGAAGTAATCAAAGTTTGTACCTTTATCACTCTTATAAATTCTATTTTTGAGTTTAAGTGTTCTAAACTTTTTTCAATTGAGCTTTCAGAAGCATTTAAAATTATTGTTTGTCCAATTTCTATTTTTTTCCCTCATTAGGACCTACTTCAGCTCTAACAGTTGTCGAATAACTATTACAAAATTTATTAATCTGAAACCACCTTTTACCGAAAGGTAGCCATAGACTGACTTTTCAGTTGATATAATATCAAGACAGTCTTTATCATTTAGATTGTAAGTTCTATAACATTCACCTTTTATTTCAGAGGTGTCTTTTTTAATTATCTTAAAATTAACATT
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/metasequences1.fasta Wed Mar 21 17:15:25 2018 -0400 @@ -0,0 +1,12 @@ +>1/1 +CTGGGAATGGGTGTCTTGAGATAATTTCTTTATTCAATTAAGCTCTAAACCTAAATTTCTTACTTCATCTTTAAATAAGAATTTAAGAGGTTCGACTAATTTTAATCTCATTTTTTTTGGTAATCCGCCTACATTATGATGAGATTTGATTTTTGACGTTTGGCTTCCTGTTACTGATCTGCTTTCAATAAGATCTGGATAAAGAGTTCCTTGAGCTAAAAATTTTACATTCTTAATTTTTTTTGCATATCTTTCAAAATTTTAATAATAAATTTCCAATTATTTTTCTTTTCTTTCTGGATCTGAAACGTTTGTTAACTTTTTTAAAAATTCTTTTTCAGCATTAACGTATATTAAATTCATCTTTAGCCTTTCTTAAAAGTATTAACTACTTGTTTTCCTCATTTTTCTAAGAAGACCAGTGTTAACAAAAATACAATATAGCTTTTTACCATAGCTTTATTTAATAATGAGCACTACACTACTATCAACTCCTCCTGAAAGGGCACAAATAACTTATTTTCACCAACTTGATTTCTAACCTCTTTAATTAATTTCATCTTTTGATCTTTTGATGACCAGTTTTTTTAATTTTAATATTAAGGAAATAAAATTTTTAATAATTTTTTACCATTTTCTGTATGTGGTAACTTCAGGATGAAACTGAACACCATAAAATTTATTTGTATTGTCTCCAACAATTGCCAAATTTTGAATTTTGACTTGATGCAATTACTCCTAAAATTTTAGGTAATTTTGAAACTTGATTCAGCATGACTCATCCATACTTTATGAATTTTTTTTTGATTAAAGAAATTTTTTAATTAAAAGACTATCTTTTTTTTATAGACATTAGCTAAACCAAACTCCCGATGCTTTGATTGTTTGACCTTTCCACCATTTAATTTTGACAAGATTTGGTGACCAAACAAATTCCTAATATTGGTATATTGTTTTTAAGTATTTCTTTATCAAGAAATATCTATTAATTTCATAAACGTTAAGGGGACCTCCTGATAAAATGATACCTTTAATTACTTGTATCAATATTTTTATTTTTAATCTTTTTATGACTAATAATTTCTGAGAATACCCTAGTTCTCTTATTCTTCTGGCAATCAATTGTGTAAATTGAGACCAAATCTATGATTAATATTTTATTTAAACTTTGATCAAGAATCATTTTTTGGCTCTATATTCGCTAGAGTCTCCAAAATATCTTTATTTATCATCACATAGTTTTTTACAAACTTTTGTAAATGTTATTTTGATAGATCTTTTACTTTTGAATAATTTGATTTTCTAAAGCAATTTTCATTAACATTAATATTGGCTTCTTCGTTATCAGGTTCGATTAATAATGTTGTTTCTAAATTTTTTTCTTTCTTTTTTTGATCCTCTTCAAAATTATAATCTTTGCCAAGTACAAATATGAATTTGAGTCTTTAGGATTAAAAACATACTTCTTTCAACATAAATCTTGCATCGTCATATTTTTCTGTCTTTAAAAAGTTCTAAGCCTTTATCAAAAAAAATTCTCATTACCAAAAGATGTTGCTTGCTAAATTTATGAAAAATAAATTAATACAGTTTTTTTTAATTTTATCATCATTATCAATCATCATCTTTTTACTATATCAACGTTATGTACCATACTTTCGTAAATCCAGCTTTTGTAATCTTTACAAATTTTGGTTTATTTCTTAAATATTTAATTGTGTCTTAGAACCAGATAACCATCGACGATTTCAAACCGACCAATAAGTTGGAAAATTATTTTTCAACCTTACTTTTATATTTAGCAAATCCTTCTACACCTTCAGGTACATATTTGAGATATCTTTTTGTTTTGATTGAAAATATCTATCAGCTGAACCTTTATTCATAGCACCCCACTGATCCATACCTCTAAAACTTTTAATAACTTTCCCACCTCTTCTAATTAATTTACCTGGGGTCTCATCGGTGCCTGCAAATAAATGAACCACCATCACTGCATCTGCTCCTGCATCAAAAGCTTTGGCTAAATCACCAGTGTATTTAATGCCTCCATCAGAGATAAGATCTTAACATTTTTATTTTTAACTCGTTTCTTAACTGTTAAAATTGCACTTAACTGAGGAACTCCAATACCTGCCACTAATCGTGTGGATACAGATAGACCCAGGGCCTATACCCACTTTAATTATATCTACCCCTAATTTTAAAAAATGTTGCAGCTTCTGGTGGTAGCTATTATTACATGCACACTAAAGCTGTCTTTTATTTTTCTTTTTTTAATGAATTTAATTATCTCTGAAACTTTTTGTATGACCATGGG +>2/1 +GCAAGATCTGATTTATTATTGCCAGAATCACAATATGAATTCTTTAAAGTTAAGTTAGAACAAACAAGCATCATTTCACCATTTAATGGAGTTATACAGAATAGGTTTTTAGATACAGGTACAGTAATTAACTCAGGGATCCCTATACTTGAGATCATTGATTCGAATTATGTTGAAGCACATATTTCTGTACCTGTTATCTATTTAGAAGATATGCAAATCAATGAAGAATATAATTTTGAGTTTGATGGTGAGATAACAAAAGCAACTTTCGCCAAGCTAGCACCAATGTCTCCGGGCGTTCAAATAGTAGACTGGCGATATTTAAGTTTAGTAAATTTTTTAATCCAGGCCTCAATAGCAAACCTCCAATTAAAAATTTCCAACAAGCAAAAGGTACCTGGGTTCCTTTAAAGTCTCTAATCTCAATCAGATCAGGGCTTATGGACAATATATACAATCGACAATAGCAATACTGTTGTTAGAGATATAGTAGAAATAGTCCATTTTGAAGATGATTATGCATTCGTTAGTGGCACCATAAAAAATGGTGATTTAGTTGTCTTAGGCGGAGCATCTAAGATTATTGAAGGCAAAAACTTAATTAGAAGAAATGAAATTTATAAGTATATTTCTTGATAGACCAAGAATACTCTTTTTAACTTTAGCTTTCATATTACTTTCTGGCATTTCTTCAATATATACATTACCAATTCAAGAGAATCCAGAGTTAGCTGAGAGATGGGCGACTGTTACCATTTCATATCCTGGAGCCGCACAGAGAGAATAGAAACACAAGTTGTAGATATCTTGAAAATAAATTGAGAGAAATTGTTGAGCTTGATATCGAAGATTTAGCGTCAGTAATTACTCAAGGCTTTTCTGAAACACTAGTAGAATTGCAACAAAGTGTTCCACCCTCATTAATAGAAGAAGTTTGGTCAAAAGTTCAAAATAAAATTGATCAAATAGAAACACCTGATGGAGTAACCATGTTGCTTGAAAGATCATCAGGACCACCTATAACTGTTGAGTACATTATTGATTGGAGGGTGAAGGAAATGCGCCAATTATTATGATGTCCAGATTGGCACAACAACTACAGAAAAGTTGAGTTCTGTTCCAGGGACAGAAAAGACAGCTATATATGGGAGAGGCAGAAGAAGAAATAGTTGTTGAAGTTGATTCTGCAAAAATGTCATCCCTAGGATTAACATATCAAGAAATCAAGTTCAGCCATAAGATCATATGACAATAAAAAACCTGTTGGGGTGGTCTCTGATGAATATTCTGAATTTTTAATACGATTAAAAGATAACATAACGAGTCCTCAAAAGATTGGCGAAATACCAGTTAACGGTAATAAATCAATCCGAAATTATAAGGCTTCAAGATATAGCCGAGGTCTCGATGCAACCCGCTAATCCAATCGAAGACATATTTTTATACAATGGTCGAAGAGTTTTATCGGTATCTGCTACAGGATCATTTTCACAGAGGTATTTGAGTATGTAGAAAATGTAGATGTTCAAGTCGATAAAATGCGATTAACATTACCTGAAGAATTCCAAATTGAAAGAATATACGATGAGTCGATATATGTATCCAGTAAATTTGGAGAACTAATTAAAAGCTTTGCATTAGCAACTTTTTTTTGTATTAAGTCTAAGCTTCTTTTTCTTAGGAATTAGGCCAGGAATAATAGTAACCGCTATTTTGCCACTTTCAGTATCTTTGGTTTTGCTTGGTTGCAGATTAATAGATTTACCCCTTCACCAAACATCATCACCGGAATAATTATTGCCTTGGGGCCTCCTAATTGATAATGGAATCATAGTTGTTGAAGATTATAAATATAGAAGATCAATTGGACTTTCAATTAGAGAGTCTATAAATCAAACATTAGTTCACATATCAACACCTTTGTTGGCTGCAACAGCAAACTACTGTTTTTGCGTTCATGCCTATAGTAACTGGGGAAGGATCTAGTATTGAATTTGTAGGCGGTATGGCGTTAACCGTAATAATGTCAATTATTTCATCATTAGTATTAGCATTGATTATGGTTCCTGTTTTGATGAGTTACATGGAACGCATACCTTATTTTGCAATATACAATGTTCATGAAGAGGCGATATAAAATGAGAAGATTCTAAAAAAATATAGAAAATTCTCTACCTGGGCTTTGATTATACCGACGACGAGCCATATTGATTTCAATTTCTTTGCCACTTATTAGGGTTCTTTGATATTTGGTTCTATTCCAAAGACTTCTTTCCTGCAAATGATAGAGATATGTTTCGAATTCATATAGAGCTTCAACAAATTCATGCTTCAACAAAGACACTTGAAAGAGCTTCAGGAAACTTAGACAACAGGTAATTGATAGCAATCTTTGATAGAAT +>3/1 +TTGATCGATACAAAAATAAACAAGATTTTATTCAAAAATATATCTTTTCCCCGGAGGGTTTTTGCCCAATAAAAATACTATCAATAAACTAGTTTCTAAAAATGGACTAACTGTTAATTCATATATTTCATATGCCGGATCATTATGCAGATACACTTGGCGATTTGGAAAAAAGAATTTTAATAAAAAGTGGGATATGATTAAAAAACCAAGGTTTTGATTTTAACCTTTAAGAGAATGTGGGAATTTTATCTATCTTATTGTGAGGCTGGATTTAAATCAAAAAATATTGATTTAATTCAATTTTCGGTTTCAAAACAAATAATGAATATATTGGAGTTTTTTAGATGCGTCATATAAAAATTGTTAACTCTATTTTATTGATAATTTCACTCTTCTTAATTACAAGTTGTTCAAACAACAATTGCAATGAAACCTGGAAGATTTTAAAAACAAAGAACCAAGACTTATAATAGAGGAGTATTTAACAGGAAATGTTAAGGCTTGGGGTGTTTTACAAAATCGTTCAGGAAAAGTTACCAGACAATTTTCAGCAGATTTGGATGGATCATGGGACGGCAAACAATTAATTTTAAAAGAAAAATTTAATTGGGATGATGGCGAAGTTCAAAATAGAGTATGGACTATCACTAAAATTGATGAAAATAATTATGAAGGTACAGCTGGAGATGTTGTTGGTAAAGCAATAGGTATTCTTATGGACCAGCATTTAAATTTGAGTATGTTTTATTAGTTCCTGTTAAAGGTAAAGAAATGAAAATTACTTTTGGATGATTGGATTTTTAAACAAGATGAAAGAGTTGCTATAAAATCGAGCGACAATGACTAAATTTGGTTTTAAGGTAGCAGAATTAACAGTCGTATTTTGTAAAAGATTAAATTTTTTCTTTATTGTGTTTTTATAGCTAACAATAATCATTCTCAAAAAAAATGTGAGATTGATTATCATTCGCCAATAATCTTGTTGTTTCTTCATTAAAAAAAAAATATTATTAAATAATGGAAACACAAAACTATAGTTGTAAAAAATGTGGACTTACAGTTTCATCTATATGCTCTAAATGTGATAGAGTTGTAGATGTAAAAGTTCTTGATAACGGTTGTATTGTTCAAAAGACAAAATGTAATGATTTGTGCAAATGTACCTGTTATTAAAGATGTTTGTTCACAAAGTTAAAAATAATTAAAAAGAAGTCTATTTATCCTATAAACCAAAAATGGAAGTTACAACAGGTATATTCAAAGCAGCCGAAAATATATTTAGAAATAATAAGGGTTCGATATTAAGAACTATTGTTTATACTATTGGTCATTTTGCTATTGCCAATAACTGTTCTTATGTTAGTTGCCTGATGTATCCATTTTGTTATAGCTTTAACTGATGCAATTATAGAGCCTCTAGCTAATTCATTTGGTATTTCATCTTGATAAATGGTGGATTAGCAAAAATCTTAATAAAAATTAATTTTTTTTTTGATATTTTGTAAGTTTACTTAGTAAACCCAAAATAAATACTACTAGGTTAAAAAGCTCAAGAATTTTAAGATTAAAGTGAGTGTCTTAGGAAAAATGTATCTCAAAATTGTTTTTATTAATTAATCCATCATAAATTTTATCTGCAGCATACTCAGAAGTCTTTAAAAATGGCATTTTAAAATCATTTTTATCGGTCATTGGCGTTTTAATAAAACCAGGTGAAACCAAACAAATACGGACATTAAATCTTTTAAAATCAAAATATAAACTTTCAGCTAAATTATTTTTAATGCTGACTTTG +>4/1 +CATCAGCTTTGATGGTCCGCTCTTCCACACCCTTGGCACCATCGACCACCATCAGCGCCAGAGTCGACCGCGGTGAGCACCCGGTAGGTATCCTCCGAAAAGTCTTCATGGCCCGGCGTGTCTAGCAGATTGACCACCCGATCCTTGTATGGGAACTGCATCACGGAAGAAGTCACCGAAATCCCCCGCTGCTGCTCCATGGCCATCCAGTCAGAGGTCGCGTGACGGTCTGATTTCTTGCCTTTGACTGTTCCGGCCACCTGAATCAGATTGCCGAACAGCAACAATTTTTCAGTGATGGTGGTTTTGCCGGCATCAGGGTGAGAAATGATGGCCAGTACTCGCCGGCGATCAATTTCGCGCTGTAATGATGCTGTTGGTGACACGACAAACTCGCAGTGGCTGCAAGATAGACTGTAACGCGGCCGCATTATAGCAGCTGCTTACATTCGCCACATCAGCTCCGGGCACCGGATCGGCAGATGTCAGCGGCCTTCGGCTCAGAGCCGCCATGCATTACAATGAGTTGGCAAGACGAGACCGCACCAGATTGCCCATCCATTACCAGAACGGACCAGATCATGAATTTTACCCTGACAGAACAACAACGCGCCCTCCAGCAAGCGGTCAGAAAATTTGCGCAACAGGAGCTGCCGGACATTGCTCGACAAATTGAGGTTAACGATGAACCAGTGGATCTCGCCCTGCGCCGTCGCTATGGCGAACTCGGCTATCTCGGGTGAATCTCGACAGCTCGGTCGGCGGTGGTGGCATGAGGTCATCTCGACGCCGTGATCGTGCTGGAGGAAGTTGCGAAGATTTCAATTGCGGTGGCGTTTCCGATCTTCGAAGCCTGTTTTGGCCCCAGTTTGGCCATCGCCCACTTCGGCAGCGAATCACTCAGGCAGCGTTATCTGCCCCAGGTCTGTACCGGGGAAAAAGTGGGTGGCGGTGTCCATGTCAGAGCCGGGCGCCGGATCTGCACTGGACTGATCTCATCACCCGGGGAGAAATCACCGGAGACAGAATTATCCTCAACGGAAACGAAACGATGGTGCTCAGGCGCCGGACATTCGGAAGCTTATGTTGGTGTACTGCCGACTCTCGGATGCTCCGGGCGCCAGGGGCATCGGAGCTGTGGTGGTGGACAAAGGCACCGACGGCTTCAGTTTCGGCAAGCGGTGACCACCATATGGGGCTTCAGAGGCGTTTACAGTTGCGACATGTATTTCGACAATGGTCGAAGTGCCGCTGGAAAACAATGCTCGTTACCGGCCCGGCAGTTTCGGCAAGCTGATGGATGCCTTCGACCTGGAACGCCTGCGGTAACACGACCATGTCACTTGCGGGTGGCGCAGTCCGCATTTGACTACGTGCTGAACTACAGCCAGGAACGTGGAGCAATTCGGTAAACCACTGGTAAGAATTTTCAGGCGATACAGATACAGCTTGCCCGAAATGAAGATGAAGCTTGAAGCTGCGCGTCTGCTGCTTTACCGCGCAGTGGTCAATGCCGAATCGGGCCTGCCGTCACTTGGCGAAAGCTCGGTTGCCAAATGCTTCGCCAATGAGGCTGTCCGGGAAGTGACGGGTAAAGCGATGCAGATCATGGGCGGGTATGGCTATTCCAAGGAATTTCCTATCGAGCAAAAGCTCCGTGACGCCTGGGGCTGGGGTAATTGCAGGGGGATCAATCGATATCCAGAAAGTGATATTACCTCTGCACTGGTAAAACCGACGCTTTAATCAGCGAGCCAACTGAGCGATCTAGTGCAGGGGTCGACCCGTCGGACGACATCGGCGCTCGGCGAAATCCGGGTGCAGTTATCGATCTGTTTGACCAACAAGAGATCGTGACGAGAGAGATGATCATGTTCAATGTCTGAACGAACACTCGACGTCTTCCAGCATCACGCAGACGACATCATCATCGTCAATATCGACGACGATGCAGGATTTAAATCCGTCTACCGTATTGATCGAGGCCAGCGAACCCACATCGAACTGATAAATCGGCAAAGAACCGCTGGCACGCTGTAGCAATCCATAGGAAAGTAAACGCGACCCCGAAGCCTGCCGCCGCGACCACGTTAATAATTTCCACCACTTCCGGATCGGTCAGATCACCCGAACGGTCTCGGCAAGTGGCTGATTCACCTCTAACTGCCGTCGATTAATCAACCTCAGAAACAGATCAATGTCTCCTGATTCCATTCGAGCGTTTCTTCCGAGACAGATCGGGTGCTGTCTGAGGACAGGCTCTGCACGTCAGTTTCGATAGTCAGATCCCGAACTTTAGTGTCCGGCGGACCAAGGCACTACCATTGAGACGGAACCAGTAGCCGTCGCTACGCTCTGCGCTGAGGCGCCAG +>5/1 +TTTTAGATGATACAGACGAAAATTTTTCAGGAAAGTTAAAAAAATTTAATTTAATTGGAATTCCATATCAAATTCTAATTGGAAAAAATCCTGATAAAAATAAAGTTGAGTTTAAAGAAGTGGGGAACGATAGTAAGATGATAAGTCTTGAAGAAGCCCTTAATTTCATTAAATCCAAAAAAATAAATTGATTTCAACTTTAGAAAAAAAAATAATTTTTAGATATCTTAAAACTAGAAAAAAAGATGGTTTTTTAAACATCATCACTTTATTCATTCTTAGGCATAAGTTTAGGCGTGGCAGTTTTAATTATAGTTATGTCTGTAATGAATGGATTTAGGTCAGAGGCTGATAAACAAGATAACTAATTTCAACGCACATGTAATCGTGAAACCCTATGAAAAAAAATAGAACAAAAAAAATAGGTAACGAGTTTTTACAAAATATATCTTCAAATTTGATATTAAGTAATAATGGAGAGGGAATACTTTTAAATGATGAAATTACTAAAGGTATTTTAGTTAGAGGCTATTCTGAAAATGACTTTCAAAAACTAAATATTGTAAATAATAAATATTTTAGAGGTAATAAAAAGATTTTAAAGACAATATATCGATAGGGAGCGATTTAAGTTATGACCTTGAATTAAAAATTGGTGACCAGATTTCAATAATTTCACCTTCTGGTGAAAATACACTTATTGGATCTATACCTCGACAAAAAACTTTTAAAATTGATTCTATATTTGATAGTAGGTTTGCTGAGTTTAATAGTTCTGTTGTGTTTATTAATCTTAAAGATCTACAAGGTTTGTTTGATTTAAAAAAAGAAAATAATTTCTTAGAGGTTTATTTATATAAACCTGACAAAATTGAGATTTATCGTGAAAAACTGTTGTCGATTTTTACTGACGAATATATATTTACTTGGTCAGATCTAAACAAACCATTATTTTCTGCTTTAAAAGTAGAGAGAAATGTTATGTTTATAATATTATCCTTAATAATTATAGTCGCTGCTTTTAACATTATTTCGGGTCTTACTATTTTAGTAAAAAATAAAACTAGGGAAATTGCTATATTAAAATCAATAGGTGTTTCTAACTTTTCCATTCGAAAAATATTTTTTTTATTGGATTTTTAATAGGATTTTTAGCAACAATTATGGGAGTTGTTATAGGCGTAACTTTTTCTCTTTATGTTGAGGAAATTAGAATGCTAATTAGCAATGTCTTTAATATAAGTTTATTTCCAGAGGAAATATATTTTTTAAGCACGATACCATATCAGATAGATTTTTGGTCAATATTTTTGATTTCAAGTTGTTCAATTATAATGACCTGTTTAGTCTCAATATACCCTGCAACTAAAGCAGCAAAATTAGATACAATTAAATCATTAAAATATGAATAACATTATAGAACTAAATAATATTTCAAAGATATTTAATAATCAAAAAAGACCACTGTTCTTAAAAATTTAAATTCAAATTCAAAAAAGGAAAAATTTATTCATTATCAGGGCCTTCAGGATCTGGAAAATCCACATTACTCAATTTATTATCTTTAATAGATAGACCATCATCCGGAAATATCAAAATTGATAGTCAAAATATAAATCACAACGAAATTGAGATTAATGATAAAATTAGATCTAATAATATTGGAATTGGCTATCAAGAGAAAAATTTACTAACTGATTTTACAGCTATCGAAAATGTTTGCTTAGCTAGCTTAGCTGCTAATAACAATCAGAAAATAGCAGAAAAAGAATCATTAAAAATTATTCAAAAAGTTGGCTTAAAAGATAGGACTAATCATTACCATCAGAACTATCAGGAGGAGAGTTGCAAAGAATTGCTTCTATCGAGAG +>6/1 +CATATCAAAATAATCATCGCCTTTTTCAGATATGTTAAGGTTAGTTATATTGCCACCTGCACTTCCAACAATGGTTGCTAATTTACCTAAAGATCCAGGTTCATTTTTAACTGAGACTTTTATTCTTGACGAAAAATACTGCTTTGGATCTACATCTTTCCATGAGGCAGTGATCCAATCTTCTTTTTTGTTTCTTTATCTAGCTCCTTACATAAACTGGAGTGAATGATTACACCTGAATCTTCTGATGTAAGTCCCAAAATATTTTCATTGGGTAAAGGGAAACAGCATTCTGCATAATGAATTGCGATTCCAGGTTGGAAGTTACTTATCTCTAAAGGCATCTTATCGTTTGTGTCTCTCTTCTGTATCGAGAAAAAAATGATAAAGTTGAACGGGGCTTAAGCTTTGATAATTGATGTGGCCTTTATACTTCCTTTACCAATTGCAACAAGAAACTCCTCAGGACTTTTCCTATTAAAAATTTTTGCAAAATTACTAATTTCTGTGTTTGAAATATCTTCATTTCTACCTGTGACTTTGTGTAATATTTTTAACCCTAGACTTGTAAATTCATCTTTTTCTTGCTTTTTAAAAAATCTTTTTATCGATGACTGCGCCTTTGCAGTTGTAACAATATTTTCCCAAGTTTCAGATGGAGATGGTTTTTTTGATGTTAGTACTTCAATCTCATCTCCATTTTGAAGTTTTGTAAATAAGGGTCTAGGTTTTCCATTAATCTTACATCCAACGCAACGATTTCCAATTTCAGAATGAAGGGCATAAAGCAAAATCGATAGAGTTAGAATTTGCAGGCAAATGAATTAAGTCACCTTTCGGTGTAAAACAAAAAACTTGATCCTGAAACATTTCTAATTTTGTAGCTTCAAGTAAGTCCTCAGAGCTTCCACCGCTGTCCAATATTTCTACTAATCTCTCAACCAAAGTAACATTAACTGGATCTGAAGAAGAGTTATCTACTAAATTATAATTCTCTTTATAGCTCCAGTGTGCCGCTATACCCTTATCTGCTATTAGTGTTCATTTCATTTGTTCGAATTTGAAGTTCAACTCTCTGTCTTTCAGGGCCAACAATTGTTGTATGAATTGACTGATAATTATTAATTTTTGGTGTCGATATATAATCCTTAAATGAGCCTGGTACAGCAGACCACCGGTTATGAATGATGCCAATATACTATAACAATCTTCAATGCTATTAGTGATAATCCTATAAGCAAAAAATATCCGACAATTGTCTAAAAGCAATTTGGCTTATTCTGCATTTTATTCCATACAGAGAAGATTTTTTTTTTTCACGTCCTATTATTTGACAATCAATTTCATTTTTTTCTAAAAGACTAAAGAATCCTTGTCTTTATTTTATCAGTTAAATTAGATTTATCTTTCTTTAAATACTCAATTCTTGTCATCAATGAGGAATATGCAGATGGATTTAAAATTTGAAATGATAAATCTTCCAACTCGTCCTTGAATTCATGCATCCCCAATCTTCCAGCAAGGGGGCATAAATTTCTAATGTTTCCGATGCAATACGTTGTCGTCTTTTTTCCTGTGGAATAAATTGAATCGTTCTCATGTTGTGTAAACGGTCAGCTAACTTTACTAACAAAACTCTTGATATCCTTCGACATTGCTAAAATTAATTTTTCTGAAATTTTCAGCCTGGAATTTATTTTCAGTATACGTTTCAATTTTTGACAGTTTTGTAACGCCGTTTACTAATTGAAGGACTTCTTTTCCAAATTTTTCTTCAATTTCATTTTCTGTAGCAAGAGTATCCTCAAGTGTGTCATGTAAAAGGCCCGTTATAATTGTGGAAGTATCTAACTTTAAGTTTAATAGAATATCTGCAACTGCAACTGGGTGAGATATATAAGGATCACCTGAATGCCTTTTTGTGACTTGTGACACTCGACT
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/metasequences2.fasta Wed Mar 21 17:15:25 2018 -0400 @@ -0,0 +1,8 @@ +>7/1 +TAAACTATAAATACCTTTTGTATATTTTTTGTAAGTCTCGTAAGAATTTGATCCAACAGCAGCTTGTAAAAGATGAATTAATTTTCCTTGGTATTGGTGTGTTTCACCATTTTTTCTGTATCTATAAATTCCACCTATAGGTAAAATATCTGAGTGAACATCAAAAGCATCTTTATGAATAGCTCTAATTTTTTTTTCAATACCAGTTAAACCAATTCCTGAAATTTTTGAAACTACCCCTGGAAAATAATCTTTAACAATTGTTCTGCTTAAACCAACAGTTTCAAAGTTGCACCCACCTCTGTAAGAGCTAAGTACTGAAATTCCCATCTCGACATTATTTTTAACAAACCAAGATTTACTGATTTAATATATCTAGCAACGCACTCATCATAGGAAAAATTGCCAAAAGTTTTTTGGAATGTCTTTGATATAAACTATCAAATGCAAGGTATGGATTTACTGTTGTGGCACCGACACCTATAAGAGTAGCAAAAGAATGTGTATCAAGAGCATCTCCTGTTTGAACATTAATAGAAACATATCCCCTTAAGCCTAATTTTATTAAATGAGTATTTATTGCACCAATACATAAAAGCATTGGCATAGGAAGTTTTGTTTCAGATGTTTTTTTATCAGATAGAATAAGTTGAGTAACACCTTCTCTAACTGCTTTTTCAGCATCTTTTCTCAATCTTTCAATTGACTCTTCAAGGGTTTGATCATCATTGAATGTACACTCTATAGTTTTATAGTTATCACCAAAGTATTTTACGAATTTGTCAAATTGGGTATTTGATAGAATTGGACTATCTAATACATAAATATTTTCTTCAGTAAGATTTGAAAAATCAAGGATATTTCCAAGATTTCCAAATCTAGTTTTAAGACTCATTACTTTATTTTCTCTTAACGAGTCGATAGGAGGATTGGTTACTTGACTAAAATTTTGTCTAAAAAGTGGTAAAGAGGCTATATTTATCTGATAATACAGCAAGTGGTGTATCATCACCCATCGAGCCAGTTGCCTCTTTTGCATCTTCTGCCATTGGATGCCAAGATTAATTCCAAATCCTCTAGACTATATCCAAAGCAATGTTGTATCTTTTTAAATCAGTTCCAGAAAACTCATTTTTTTCATTTTCAATAGTCAAAGTCTTATCCAAATCAATAATTTGATTATTAAAGTGCTTATATTCCTTGGCTAAATAATTTTTAATTTCTTTATTTGAGTAAACTTTTCCTTTTTCAATTCTAACGCCTAATATTTCCCCTGGTCCTAATCTTCCTTTTGAAACAATTTTTTTTTCATTTAGGTCAATCATTCCAGTTTCAGACCCAGCAAACAATAGTTTATCTCTTGTTACCGTATATCTAAAGGTCTAAGTCCATTTCTATCGCTTGCCACAATTACCCATTCATTATCTGTTGCTGCTATAGCTGCAGGACCATCCCATGGTTCCATAGTGCTATTCAAAAAGTTAATAATTGTTGATGATCTCGTGAAAGAACTTTACTTTTTTTAGACCAAGCATCGGAATTAGTATTAATTTTGCTAATGGTGCTGAATGACCAGAAATATTTAAGAGTTCAAAGACATTATCTAACGAAGCAGAATCCGAATTACCCGCTGGAATTACAGGTTTTAAATTTTCCATATCTTCAAATAGAGGACTAAACATTTCTTCTTCATGAATTCTCATCCAATTAATATTTCCTTTTAAAGTATTTATTTCTCCATTGTGTGCTATTGACCTAAATGGTTGAGCCAAGTCCCAACTGGGAGCTGTGTTAGTTGAAAACCTTTGATGAAAATTGCGTATCTTGATATAAAACGTTCATCTTTTAAGTCCTGTA +>8/1 +CTTTTATGGTTTAAACGGTAAAGCAAGTATTATTAACGGACCCGTAGTTGCCTTTGAAGTAACTCAGCAAGGTTCTAACGGACTATATCTACTTTATTTAATGGCTGTTTATTTAGGAGTTTTGCAGTTACGATGTTGCTGCAATTCACAAGTTATTTTTATGAGCAGTAGCCACAAACTTCTGCAAAATTGATGAAGAGGTAAATATTTCAAAGGTCGATAAAACAAAAATAAAGTTTAGTATCGAAAATATGGAAAGCCAATAATGGAATTATTTTTTTTAGCTATATTAGTTTTAATTATGATTGCAGCTCTAGCTTCAGGGTATCCAGTTGCCTTTGCTCTTCCTGGTTCAAGCTATCATATCTAATCGGTTTAGCAGCTTTTTTTGGTTATATTTTTTGCTGGCGATGTTGATGCTTACTTCGCTGTCGATGGTCCAACCGAATGGCTTGTTGCTGGAATTACAAAATTTTAGAAGTAATTACTGGGACGTCGAGACTGACACTTTAATTGCAATTCCCTTATTTATTTTTATGGGAATTATGCTTCAAAAAATCAAAAAATTGCTGAGGATTTATTAATAACTATGGGTCCAATTATTTGGCCCCCGATACCTGGTGGTTTAGGTATTTCGGTAATATTTGTTGGTGCATTATTAGCTGCAACTACAGGTATTGTCGGAGCAACAGTCATTGCAATGGGATTAATTTCATTACCTACAATGTTTAAACAACAATTATGACAGAAAACTTGCAAGTGGAATTGTTTGCTCTTCTGGAACTCTAGGACAGATTATTCCGCCATCAATTGTATTAATTATTATAGCGGACCAATTAGGCGAGGCGCATCAGATGTTGCCAATAACATGAGGCAGAACGATTATAAAGCTTTAACAGCGCGAATTTAACATGCCAGGTGAATTTAGAGTAGGTTTCATCCAGTGCCGGTGACATGTTCCTGGGAGCACTTTTACCAGGGAATGTAGTACTTGTAGCTTTATATATGATCTATGTATTGTTTCTATGCGAAGAATAAAAAAAGGGGTTGCCCCACCTGTTCCATTAAAGGAAACTTGATTTCAAATTTTGGATGAAAGTTATTGTTTTAATTATTCCTCCACTTGCATTAATTTTTGCTGTTTTAGGATCGATTCTTATGTGGTATTGCAAGCTGTGAACCAAGCTGGTTCTAATAGGAGCAATTGGAGCAACATTAATGGCGGGTTACCGTCTATTTCAGGTAAGAAAAGTGCCTCTTCTATCACTTATAATGATAATTGGATCATTAATACCCATTACATTTCTTTTTTGCATCAAATTATGACTTAACATAAAAAATATAGAAGAAGAGATTTAGGAGCAATTTATATAACTGCTATTTTTGTAATCACTTGGTTTATGGCAATAGCATGGAGTTTTTGGAGAACATATAAAACTGAAAATGCTTCTTAAAGAAGCAGTAACCGAAACGTGCGTTACAACTTCGATGGTATTTATTATTCTATTTAGGTGCTGCAATGCTTACATCAGGATTTAGAGCATATTGGTGGTGAAGAATAGTAAGAGACTTCCTTCAAGATTTACCCGGGGGCTTGGACTCAGTTTGTAGTTGTAATGATTGTAATATTCTTACTTGGGTTCTTTTTAGAATTTTATTGAAATCGCTGTTGTGGTTGTTCCAATAATTGCACCTATATTATTAGCTGAGACAGGAGCAAACCGTTACCAGCGGTCTGGTTATGGTGTTATGATTGGTGTCATATTTACAAACCCTCTTTTTTAACTCCCCCCTTTGGTTTTGCCTTATTTTATTTAGAAAATGGTGTTGGTAAAAGTGGTACAAACATTAGATATTTGGAAAGGTGTTGTTCCATTTATAATTTTACAACTCATTGGCCTAG +>9/1 +AAGAAGGCTATCCATTCGGCGGGCCGCCTCGCCAAGCGCCGACGAGCGCCGCAATTCATCAACCAGCGTTCGAGCCGTCGGGAGACCCGCTGGCGTACCAGCTGTCAAAATCGGCCCTCATCCCGGCACCAAGCGACTGACGGAACAGTACGACAACGCCGTTCGGTGCGCGCCGTCCAAGATCAGAGCCACAGGTGTTGGCCCCGTCAGCACCAGAGAAATTGAGAATGTCATTGGCAATCTGATAGGCATTCCCGAGCGCCCGGAAACAATCACCGATGGTCGGGCCGCGCCGCCATGAAGCGCCATCGCCGCGACGCCCTCAAGCGGGGCTGTTAGCAGCGGAGCTGTCTTGTCGCCAGCCCCCTGAAGATAATGGTCCCAGTCCTTGACCGGCCGGACGTCGAATTCCCGTGCTTCGCCGATCGTCGTCGTCTTCATGTGCGTTGCCAGGATTTTCACCAGCATCGGTGTCTGTGATCGCTGCGCCGCCTCAGCGGCGAGTTCGAATGACAGGGCGACCAGCCAGTCACCAAGGGTCAACGCGACATCGCGGCCATAGACCGACAGACAGCCGGACGGCCGCGGCGCAGACGGTCACCATCACAGATGTCGTCATGGATCAGCGAGGCGTTGTGAAGCACCTCGATGGCCACCGCCCAGTGAAGGCCGCCGTCCTGTCGACTTTCAGGAAGTCGGCGGCGCGAAGGGCCATCTTGGCGCGCAGCATCTTGCCAGGGGCGGCGAAATGGTGAAGCGCCGCATCGGCCAGCGGCTGACCAGGCTGCGGCATGCGCTCGATAACGAATTCATGGATGATTTCCGAAATGACTGCGAAACCGGAACTCCCCGTACCGGAGTCGGAGAAGATCTCGTTCACTGGGGTGGACAGGTCAGTCATGCTTACCGTGCTTCAACTATTCCACGAGTGTAGCACGTAGTAATTTCAATATATTATGTGAACACGGGCGACGATTTGGTGCCGCCCCGTTTCTCTTGATTTGTTATGCTTCTTTGCTGTCGCGTTGGCGGCTGCCCAGATTACACCGACGAAGGCGATCTTATTAACAACGTCAGCGACGTTGTAGATCACATTCAATGTCACCGCGTCAGCAGCGCCATTTAGGTAACCGAGGAAGTAGCCTAGTGGGTAGATCGCCCAGCCAACGTAACGATTAACCGCATCGTACCGAAAGACTTCTGGACGGCCTCCGGAGCGGACTCCGCAGATACCCTTCCTGCTTCACCGGCAAAAATCTCATACAAGATGTATGCCCATCCCGCCATGCCAACGACAAAGCCAAGCCAAGCGTTCACGAGACCTGCTTCGCCGAGGTAACCAGCGACAGCATTACCAGCGACCCAATCATCAGGCGCCAAAAAATGCCAGCGCTGACAACTGCGACTGCCGCTAGAATGAAGTAGAATTCAACCATTTGGAGAGGCACGGTTATTAGCCAGTCAACATACCTGTAAACTGTTGGCGTCTCACCTGTGCTGCCCATACGTCGCGCATGTAAAAGTAATGAACTGCCGCAACGATCTGCACTAGGCACCGATCGTCATAGCAGTCTTCCATTTGCCTGGCAGGCGAGCGGCTTCCATCAGGAAGAAAATTGCCGCGGCCATCATCGCCATTGAAATGGTCCAGAAAGATATGCCCACAAAGTCGGTAGCGGCAAGCATTGTCGTTTCTGCATTTGCGACTGATGGGAGAATGGCAAGTC +>10/1 +AAACTCAACAAACTTAGCGTTGTGCTTTTTATGTAGTTCGTATAGTGCAGTTTTTTTTATATTCATATTAACTCTCTAACCCCCTCTGTCGTGGTGCCTGAGAGATTTTAGCTCCTTCGGCGAGAATTTGTCTCTTTCCAGAGTTAATATGTACGGTCCTTTTGCCTGAGAGTTTCCGGGGTGGTTGCTCCTTCGGCGCTACTCAATGTAGTCTCTCCCGTATAAAATTATATTAGCATATTTTTGACAATCGTCATCAAGAAATAGTTTTTTTTTCTAGTTTAATAACATTGTAAAACTGTAGTAATACTGCGAATAATACAATTGACCCCCCAATTAAAACAACAAATGGTGGATTTTCACTCACAAATAACCATGCCCAAAGAGGTCCAAGAATAGCTTCAGTGAGCATTATGATACCAACAATTGCCGAGGGCGTAGATCTTGCTCCAATTGTTATAAAAATAAAACCAAAACCTAATTGAAAAAAACCTGCTAGAAAACCTAAAAATATATCATATGAAGAAATATTAATTTTACCTGCAACCAAATAACCAACAGACATTGCAACTATTCCAGCAATTAATTGTAACGGTATCATGTCTACATCTGGATATTTTCTAATAATAATAATTAAGATTGCAAATGACACAGGCATAATAAATGCTGCAATATTTCCAGACATTTGTCCTGGAGACAAAGATCCCCCAACCATTAAAATAATACCAGAGATAGCTAGTATAATTGATATTAAAGTTAATTTTGAAATTTTTCTTTTAAAAATAAATATCCAAAGATTGCAAAAAATTGTTTGAGTTTGAATAATAAATTAGCATTGGCTACTGTTGTATTATACATTGCAAAACATAGCCACAAAACCCTGAAGATAAAACTATACCACCGATAAGACCGGGAAAGCCTGATTTCTTAAATGCATGAAAAAACATTTTTTTTATAAGTAACGAGTAAAAAATTGATACAACTAAAATAAAAAAAGAGATCTCCAAAAAAGTATCTGCCATAATGTGGCGCCCTCGAAAGATTTTACAATCATCCTCCAAAACTTAAACTAGTGGCACCAAAAAAACTAAAAGTGGACCCGGTAATCTTGTATAAAATTCATCTTATTTTATTAATTATATTCTTAGTTTCCATAGTATAAATTTTGTATAAATTTTCTGCCTCGTAAGACTTATAATTTTGAATTTAATTTTTTCTCCAGGTGGGCATTGTGCTAACTTGTCATAATCTGCACTTATTACAACAGCAATTTTTGGATAACCACCTATTGTTCCATGATCTGAAAGCATTACTATAGGGTCTCCGTCAGCTGGAACTTGTATTACTCCTTTTCCTAATCCTTCAGACTTGATGTTTGTTTTCTTAAATTCTTAATTTTAGGTCCACTTAATCTCATTCCCATCCTATCGGTAAGTTTTGAGACAATAAATCTTTACTTGTGAAATCTTTGATTGAGTCTTCTGAGAAGTAATCAAAGTTTGTACCTTTATCACTCTTATAAATTCTATTTTTGAGTTTAAGTGTTCTAAACTTTTTTCAATTGAGCTTTCAGAAGCATTTAAAATTATTGTTTGTCCAATTTCTATTTTTTTCCCTCATTAGGACCTACTTCAGCTCTAACAGTTGTCGAATAACTATTACAAAATTTATTAATCTGAAACCACCTTTTACCGAAAGGTAGCCATAGACTGACTTTTCAGTTGATATAATATCAAGACAGTCTTTATCATTTAGATTGTAAGTTCTATAACATTCACCTTTTATTTCAGAGGTGTCTTTTTTAATTATCTTAAAATTAACATT
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/s_mga.bed Wed Mar 21 17:15:25 2018 -0400 @@ -0,0 +1,35 @@ +1/1 1811 1994 1/1:gene_1 13 - 1811 1994 0 1 183 0 +2/1 0 414 2/1:gene_1 35 + 0 414 0 1 414 0 +2/1 821 1079 2/1:gene_2 22 + 821 1079 0 1 258 0 +2/1 1960 2140 2/1:gene_3 12 + 1960 2140 0 1 180 0 +3/1 61 220 3/1:gene_1 7 + 61 220 0 1 159 0 +3/1 559 754 3/1:gene_2 29 + 559 754 0 1 195 0 +3/1 1238 1403 3/1:gene_3 3 + 1238 1403 0 1 165 0 +3/1 1581 1798 3/1:gene_4 14 - 1581 1798 0 1 217 0 +4/1 2 431 4/1:gene_1 18 - 2 431 0 1 429 0 +4/1 1464 1746 4/1:gene_2 11 + 1464 1746 0 1 282 0 +5/1 0 191 5/1:gene_1 25 + 0 191 0 1 191 0 +5/1 397 619 5/1:gene_2 13 + 397 619 0 1 222 0 +5/1 780 1143 5/1:gene_3 26 + 780 1143 0 1 363 0 +5/1 1163 1412 5/1:gene_4 8 + 1163 1412 0 1 249 0 +5/1 1811 1871 5/1:gene_5 4 - 1811 1871 0 1 60 0 +6/1 149 344 6/1:gene_1 6 - 149 344 0 1 195 0 +6/1 401 791 6/1:gene_2 19 - 401 791 0 1 390 0 +6/1 1626 1941 6/1:gene_3 35 - 1626 1941 0 1 315 0 +7/1 0 330 7/1:gene_1 32 - 0 330 0 1 330 0 +7/1 358 997 7/1:gene_2 52 - 358 997 0 1 639 0 +7/1 1076 1349 7/1:gene_3 32 - 1076 1349 0 1 273 0 +7/1 1481 1703 7/1:gene_4 14 - 1481 1703 0 1 222 0 +7/1 1747 1857 7/1:gene_5 2 - 1747 1857 0 1 110 0 +8/1 0 193 8/1:gene_1 5 + 0 193 0 1 193 0 +8/1 589 745 8/1:gene_2 19 + 589 745 0 1 156 0 +8/1 1836 1903 8/1:gene_3 6 + 1836 1903 0 1 67 0 +9/1 117 543 9/1:gene_1 3 - 117 543 0 1 426 0 +9/1 622 901 9/1:gene_2 12 - 622 901 0 1 279 0 +9/1 946 1105 9/1:gene_3 3 - 946 1105 0 1 159 0 +9/1 1143 1317 9/1:gene_4 3 - 1143 1317 0 1 174 0 +9/1 1313 1505 9/1:gene_5 8 - 1313 1505 0 1 192 0 +9/1 1548 1727 9/1:gene_6 9 - 1548 1727 0 1 179 0 +10/1 256 715 10/1:gene_1 48 - 256 715 0 1 459 0 +10/1 1136 1310 10/1:gene_2 12 - 1136 1310 0 1 174 0 +10/1 1626 1824 10/1:gene_3 10 - 1626 1824 0 1 198 0
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/s_mga.tsv Wed Mar 21 17:15:25 2018 -0400 @@ -0,0 +1,36 @@ +#seq_id seq_model seq_gc seq_rbs gene ID start pos end pos strand frame complete/partial gene score used model rbs start rbs end rbs score +1/1 b 0.275862 0.428571 gene_1 1812 1994 - 0 11 12.4805 b 2002 2007 0.494927 +2/1 b 0.338877 0.428571 gene_1 1 414 + 0 01 34.5932 s . . . +2/1 b 0.338877 0.428571 gene_2 822 1079 + 0 11 21.7601 s . . . +2/1 b 0.338877 0.428571 gene_3 1961 2140 + 0 11 11.9821 s . . . +3/1 b 0.269188 0.428571 gene_1 62 220 + 0 11 6.91386 p 53 58 4.6421 +3/1 b 0.269188 0.428571 gene_2 560 754 + 0 11 28.0223 p . . . +3/1 b 0.269188 0.428571 gene_3 1239 1403 + 0 11 2.03908 p . . . +3/1 b 0.269188 0.428571 gene_4 1582 1798 - 1 01 13.4314 p . . . +4/1 b 0.550169 0.428571 gene_1 3 431 - 0 11 17.2128 s 439 444 -2.92195 +4/1 b 0.550169 0.428571 gene_2 1465 1746 + 0 11 10.92 s . . . +5/1 b 0.256547 0.428571 gene_1 1 191 + 2 01 24.4289 b . . . +5/1 b 0.256547 0.428571 gene_2 398 619 + 0 11 12.6188 b . . . +5/1 b 0.256547 0.428571 gene_3 781 1143 + 0 11 25.1534 b . . . +5/1 b 0.256547 0.428571 gene_4 1164 1412 + 0 11 7.23104 b . . . +5/1 b 0.256547 0.428571 gene_5 1812 1871 - 0 01 3.07971 b . . . +6/1 b 0.329727 0.428571 gene_1 150 344 - 0 11 5.73124 s . . . +6/1 b 0.329727 0.428571 gene_2 402 791 - 0 11 18.3505 s . . . +6/1 b 0.329727 0.428571 gene_3 1627 1941 - 0 01 34.5233 s . . . +7/1 b 0.316101 0.428571 gene_1 1 330 - 0 10 31.4857 b . . . +7/1 b 0.316101 0.428571 gene_2 359 997 - 0 11 51.7886 b 1005 1010 2.3206 +7/1 b 0.316101 0.428571 gene_3 1077 1349 - 0 11 31.1612 b 1355 1360 0.0639296 +7/1 b 0.316101 0.428571 gene_4 1482 1703 - 0 11 13.9061 b 1716 1721 2.83485 +7/1 b 0.316101 0.428571 gene_5 1748 1857 - 2 01 1.33924 b . . . +8/1 b 0.35155 0.428571 gene_1 1 193 + 1 01 4.66209 b . . . +8/1 b 0.35155 0.428571 gene_2 590 745 + 0 11 18.2213 b 571 576 3.26585 +8/1 b 0.35155 0.428571 gene_3 1837 1903 + 0 10 5.66021 b 1824 1829 2.7516 +9/1 b 0.57209 0.428571 gene_1 118 543 - 0 11 2.97762 p . . . +9/1 b 0.57209 0.428571 gene_2 623 901 - 0 11 11.7916 p 904 909 0.279428 +9/1 b 0.57209 0.428571 gene_3 947 1105 - 0 11 2.76029 p . . . +9/1 b 0.57209 0.428571 gene_4 1144 1317 - 0 11 2.08585 p 1321 1326 4.2111 +9/1 b 0.57209 0.428571 gene_5 1314 1505 - 0 11 7.00466 p . . . +9/1 b 0.57209 0.428571 gene_6 1549 1727 - 2 01 8.49456 p . . . +10/1 b 0.314145 0.428571 gene_1 257 715 - 0 11 47.9897 b 722 727 2.3206 +10/1 b 0.314145 0.428571 gene_2 1137 1310 - 0 11 11.4563 b 1322 1327 3.1826 +10/1 b 0.314145 0.428571 gene_3 1627 1824 - 0 01 9.87622 b . . .
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/s_mga.txt Wed Mar 21 17:15:25 2018 -0400 @@ -0,0 +1,65 @@ +# 1/1 +# gc = 0.275862, rbs = 0.428571 +# self: b +gene_1 1812 1994 - 0 11 12.4805 b 2002 2007 0.494927 +# 2/1 +# gc = 0.338877, rbs = 0.428571 +# self: b +gene_1 1 414 + 0 01 34.5932 s . . . +gene_2 822 1079 + 0 11 21.7601 s . . . +gene_3 1961 2140 + 0 11 11.9821 s . . . +# 3/1 +# gc = 0.269188, rbs = 0.428571 +# self: b +gene_1 62 220 + 0 11 6.91386 p 53 58 4.6421 +gene_2 560 754 + 0 11 28.0223 p . . . +gene_3 1239 1403 + 0 11 2.03908 p . . . +gene_4 1582 1798 - 1 01 13.4314 p . . . +# 4/1 +# gc = 0.550169, rbs = 0.428571 +# self: b +gene_1 3 431 - 0 11 17.2128 s 439 444 -2.92195 +gene_2 1465 1746 + 0 11 10.92 s . . . +# 5/1 +# gc = 0.256547, rbs = 0.428571 +# self: b +gene_1 1 191 + 2 01 24.4289 b . . . +gene_2 398 619 + 0 11 12.6188 b . . . +gene_3 781 1143 + 0 11 25.1534 b . . . +gene_4 1164 1412 + 0 11 7.23104 b . . . +gene_5 1812 1871 - 0 01 3.07971 b . . . +# 6/1 +# gc = 0.329727, rbs = 0.428571 +# self: b +gene_1 150 344 - 0 11 5.73124 s . . . +gene_2 402 791 - 0 11 18.3505 s . . . +gene_3 1627 1941 - 0 01 34.5233 s . . . +# 7/1 +# gc = 0.316101, rbs = 0.428571 +# self: b +gene_1 1 330 - 0 10 31.4857 b . . . +gene_2 359 997 - 0 11 51.7886 b 1005 1010 2.3206 +gene_3 1077 1349 - 0 11 31.1612 b 1355 1360 0.0639296 +gene_4 1482 1703 - 0 11 13.9061 b 1716 1721 2.83485 +gene_5 1748 1857 - 2 01 1.33924 b . . . +# 8/1 +# gc = 0.35155, rbs = 0.428571 +# self: b +gene_1 1 193 + 1 01 4.66209 b . . . +gene_2 590 745 + 0 11 18.2213 b 571 576 3.26585 +gene_3 1837 1903 + 0 10 5.66021 b 1824 1829 2.7516 +# 9/1 +# gc = 0.57209, rbs = 0.428571 +# self: b +gene_1 118 543 - 0 11 2.97762 p . . . +gene_2 623 901 - 0 11 11.7916 p 904 909 0.279428 +gene_3 947 1105 - 0 11 2.76029 p . . . +gene_4 1144 1317 - 0 11 2.08585 p 1321 1326 4.2111 +gene_5 1314 1505 - 0 11 7.00466 p . . . +gene_6 1549 1727 - 2 01 8.49456 p . . . +# 10/1 +# gc = 0.314145, rbs = 0.428571 +# self: b +gene_1 257 715 - 0 11 47.9897 b 722 727 2.3206 +gene_2 1137 1310 - 0 11 11.4563 b 1322 1327 3.1826 +gene_3 1627 1824 - 0 01 9.87622 b . . .