annotate test-data/create/NP_000282.1.hhr @ 0:8b48a608f1df draft

"planemo upload commit b68cb41b1884703c4f1574b65a6408d7d0cca321"

Query         NP_000282.1
Match_columns 417
No_of_seqs    604 out of 4515
Neff          6.98956
Searched_HMMs 787
Date          Fri Jul 24 20:35:21 2020
Command       /home/guerler/hh-suite/build/bin/hhblits -i /home/guerler/human/fasta/NP_00/NP_000282.1.fasta -d /home/guerler/pdb70/pdb70 -o /home/guerler/human/hhr/NP_00/NP_000282.1.hhr 

 No Hit                             Prob E-value P-value  Score    SS Cols Query HMM  Template HMM
  1 2WZB_A PHOSPHOGLYCERATE KINASE 100.0  9E-114  7E-118  875.1   0.0  415    3-417     2-416 (416)
  2 1HDI_A PHOSPHOGLYCERATE KINASE 100.0  4E-113  3E-117  868.7   0.0  412    6-417     2-413 (413)
  3 6Y3A_A Phosphoglycerate kinase 100.0  3E-112  2E-116  865.4   0.0  414    2-416     9-423 (424)
  4 3UWD_A Phosphoglycerate kinase 100.0  7E-112  6E-116  855.6   0.0  391    4-416     1-393 (394)
  5 1QPG_A 3-PHOSPHOGLYCERATE KINA 100.0  7E-112  6E-116  861.3   0.0  413    2-416     1-413 (415)
  6 3PGK_A PHOSPHOGLYCERATE KINASE 100.0  8E-112  7E-116  861.3   0.0  413    2-416     2-414 (416)
  7 3Q3V_A Phosphoglycerate kinase 100.0  3E-111  3E-115  852.3   0.0  392    2-416     3-399 (403)
  8 1PHP_A 3-PHOSPHOGLYCERATE KINA 100.0  1E-110  9E-115  847.6   0.0  387    8-416     5-393 (394)
  9 1VPE_A PHOSPHOGLYCERATE KINASE 100.0  1E-110  1E-114  848.4   0.0  392    6-416     2-395 (398)
 10 4FEY_A Phosphoglycerate kinase 100.0  6E-110  5E-114  842.0   0.0  388    2-416     2-391 (395)
 11 1V6S_B Phosphoglycerate kinase 100.0  1E-109  1E-113  838.8   0.0  386    7-416     2-390 (390)
 12 3ZLB_A PHOSPHOGLYCERATE KINASE 100.0  2E-109  1E-113  840.0   0.0  394    4-416     1-397 (398)
 13 4EHJ_A Phosphoglycerate kinase 100.0  2E-109  2E-113  837.1   0.0  386    4-416     1-388 (392)
 14 16PK_A 3-PHOSPHOGLYCERATE KINA 100.0  4E-109  4E-113  840.3   0.0  395    6-416     2-414 (415)
 15 3OZ7_B Phosphoglycerate kinase 100.0  4E-109  4E-113  840.5   0.0  413    3-416     4-417 (417)
 16 4DG5_A Phosphoglycerate kinase 100.0  5E-109  4E-113  836.1   0.0  392    5-416     9-402 (403)
 17 6HXE_A Phosphoglycerate kinase 100.0  4E-108  4E-112  826.1   0.0  381    4-416     1-383 (387)
 18 4NG4_B Phosphoglycerate kinase 100.0  5E-108  4E-112  830.0   0.0  389    1-416     9-399 (404)
 19 4NG4_C Phosphoglycerate kinase 100.0  5E-108  4E-112  830.0   0.0  389    1-416     9-399 (404)
 20 6I06_A Phosphoglycerate kinase 100.0  1E-107  9E-112  823.4   0.0  381    4-416     1-383 (387)
 21 2CUN_A Phosphoglycerate kinase 100.0  3E-105  3E-109  811.0   0.0  387    8-416     3-400 (410)
 22 1FW8_A PHOSPHOGLYCERATE KINASE 100.0 8.8E-90 7.6E-94  698.3   0.0  342   74-416     2-343 (416)
 23 1FW8_A PHOSPHOGLYCERATE KINASE  99.3 3.2E-16 2.7E-20  156.7   0.0   68    3-70    347-414 (416)
 24 2Q33_B D-MONELLIN CHAIN A, D-M  34.3     5.9 0.00042   24.6   0.0   11  310-320     2-12  (48)

No 1
>2WZB_A PHOSPHOGLYCERATE KINASE 1 (E.C.2.7.2.3); HEREDITARY HEMOLYTIC ANEMIA, TRANSFERASE, PHOSPHOPROTEIN; HET: ADP, 3PG; 1.47A {HOMO SAPIENS}
Probab=100.00  E-value=8.6e-114  Score=875.06  Aligned_cols=415  Identities=100%  Similarity=1.449  Sum_probs=363.4  Template_Neff=6.400

Q NP_000282.1       3 LSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVA   82 (417)
Q Consensus         3 ~~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va   82 (417)
                      +..|++++|.|++|||||||+|+|||+++++|.|++||++++|||+||+++||++|||+||+|||+++..++.+||+||+
T Consensus         2 ~~~~~~l~~~~l~gK~vlvR~D~NVPl~~~~i~dd~RI~~~lpTI~~Ll~~gak~vil~sHlGrP~g~~~~~~~Sl~pv~   81 (416)
T 2WZB_A            2 LSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVA   81 (416)
T ss_dssp             CTTBCBGGGCCCTTCEEEEECCCCCCEETTEESCCHHHHHHHHHHHHHHHTTCSEEEEECCCSCCTTSCCHHHHCSHHHH
T ss_pred             CcccccccccccCCCEEEEEeEccccccCCccCCChHHHHHHHHHHHHHHCCCCEEEEEeeCCCCCCCCCCcccChHHHH
Confidence            45788898889999999999999999998899999999999999999999999448999999999875323479999999


Q NP_000282.1      83 VELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYV  162 (417)
Q Consensus        83 ~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyV  162 (417)
                      ++|+++|+.+|.|+++|+|+++++.++.+++|+|+||||+|||++|+++++++++|+.+++.+++.+|+++||+++|+||
T Consensus        82 ~~L~~~l~~~v~f~~d~~g~~~~~~i~~~~~g~illLENlRF~~~E~~~~~~~~~n~~k~~~~~~~~fa~~La~l~DiyV  161 (416)
T 2WZB_A           82 VELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYV  161 (416)
T ss_dssp             HHHHHHHTSCCEECSCSSSHHHHHHHHSCCTTEEEECCCGGGSHHHHTCC----------CHHHHHHHHHHHHHTCSEEE
T ss_pred             HHHHHHhCCEEEEcccCCCHHHHHHHhCCCCCcEEEEeccccchhhcCCCCCCCCccccCCHHHHHHHHHHHhcccceEE
Confidence            99999998779999999998888888899999999999999998776331111111111112234679999999999999


Q NP_000282.1     163 NDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAF  242 (417)
Q Consensus       163 NDAFg~aHR~~aS~~gi~l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a~  242 (417)
                      |||||++||.|||++++++|+++||++|++||++|++++++|+||+++|+||+|++||+++|++|+++||.|++||+|||
T Consensus       162 NDAF~~~HR~hAS~vgi~lp~s~aG~ll~kEl~~L~~~~~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~IligG~~a~  241 (416)
T 2WZB_A          162 NDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAF  241 (416)
T ss_dssp             ECCGGGTTCCCHHHHCCCCSCEEECHHHHHHHHHHHHHHHSCCSSEEEEECSSCHHHHGGGHHHHTTTCSEEEECGGGHH
T ss_pred             ecccccCCCccccccccCCCccchHHHHHHHHHHHHHHhcCCCCCEEEEEcCCCHHHHHHHHHHHHHhCCEEEeCcHHHH
Confidence            99999999999999999976589999999999999999999999999999999999999999999998999999999999


Q NP_000282.1     243 TFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSK  322 (417)
Q Consensus       243 tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti~  322 (417)
                      +||+|++++++|+|++|++..+.|++++++|+.++++|+||+|++|.+.+..+.....+.....+|++|+++||||+|++
T Consensus       242 tfL~a~~~~~ig~S~~e~~~~~~a~~il~~a~~~~~kI~LP~D~vv~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti~  321 (416)
T 2WZB_A          242 TFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSK  321 (416)
T ss_dssp             HHHHHHHCCCCTTSCCCHHHHTTHHHHHHHHHHTTCEEECCCEEEEESSSSTTCCEEEEETTTCCCTTCEEEEECHHHHH
T ss_pred             HHHHHhCCCccccceecchHHHHHHHHHHHHHHcCCEEEceeeEEecccccccccCCeeeecCCCCCCceeecCCHHHHH
Confidence            99999856689999999999999999999988999999999999999865332211111112378899999999999999


Q NP_000282.1     323 KYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLEL  402 (417)
Q Consensus       323 ~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le~  402 (417)
                      .|+++|++|||||||||||+||.++|++||+++++++++++++++++|+|||||+++++++|+.++++||||||||+|||
T Consensus       322 ~~~~~I~~aktI~wNGP~G~~E~~~f~~GT~~ia~al~~~~~~~a~~ivGGGdT~~~~~~~g~~~~~s~vSTGGGA~L~~  401 (416)
T 2WZB_A          322 KYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLEL  401 (416)
T ss_dssp             HHHHHHHHCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHHHHTTCEEEEESTTHHHHHHHTTCTTSSSEEESCSHHHHHH
T ss_pred             HHHHHHHhCCEEEEcCCCCcccchhhchHHHHHHHHHHHHhcCCcEEEEecccHHHHHHHcCCCccCeEEecCcHHHHHH
Confidence            99999999999999999999998889999999999997632247899999999999998889888899999999999999


Q NP_000282.1     403 LEGKVLPGVDALSNI  417 (417)
Q Consensus       403 L~G~~LPgl~aL~~~  417 (417)
                      |+|++||||++|+++
T Consensus       402 L~G~~LPgieaL~~~  416 (416)
T 2WZB_A          402 LEGKVLPGVDALSNI  416 (416)
T ss_dssp             HHTCCCHHHHTSCBC
T ss_pred             HcCCCCchHHHHhcC
Confidence            999999999999875


No 2
>1HDI_A PHOSPHOGLYCERATE KINASE (E.C.2.7.2.3); PHOSPHOTRANSFERASE, KINASE, PHOSPHOGLYCERATE, TERNARY COMPLEX; HET: AMP, 3PG; 1.8A {SUS SCROFA} SCOP: c.86.1.1
Probab=100.00  E-value=4.1e-113  Score=868.67  Aligned_cols=412  Identities=91%  Similarity=1.360  Sum_probs=361.3  Template_Neff=6.300

Q NP_000282.1       6 KLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVEL   85 (417)
Q Consensus         6 ~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~~L   85 (417)
                      +++++|.|++|||||||+|+|||+++++|.|++||++++|||+||+++||++|||+||+|||+++..++.+||+||+++|
T Consensus         2 ~~~l~~~~l~gK~vlvR~D~NVPi~~~~i~dd~RI~~~lpTI~~Ll~~gak~vil~sHlGRP~g~~~~~~~Sl~pva~~L   81 (413)
T 1HDI_A            2 KLTLDKLNVKGKRVVMRVDFNVPMAAAQITNNARIKAAVPSIKFCLDDGAKSVVLMSHLGRPDGSPMPDKYSLQPVAAEL   81 (413)
T ss_dssp             BCBGGGSCCTTCEEEEECCCCCCBSSSSBSCCHHHHHHHHHHHHHHHTTCSEEEEECCCSCCCSSCCTTTSCSHHHHHHH
T ss_pred             CccccccccCCCEEEEEeecCccccccccCCChHHHHHHHHHHHHHHCCCCEEEEEeeCCCCCCCCCCcccccHHHHHHH
Confidence            56777788999999999999999988899999999999999999999999448999999999875323479999999999


Q NP_000282.1      86 KSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDA  165 (417)
Q Consensus        86 ~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVNDA  165 (417)
                      +++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|+++++++++|+.+.+.+++.+|++.||+++|+|||||
T Consensus        82 ~~~l~~~V~f~~d~~g~~~~~~i~~~~~g~illLENlRF~~~E~~~~~~~~~n~~~~~~~~~~~fa~~La~l~DiyVnDA  161 (413)
T 1HDI_A           82 KSALGKAVLFLKDCVGPAVEKACADPAAGSVILLENLRFHVEEEGKGKDASGNKAAGEPAKIKAFRASLSALGDVYVNDA  161 (413)
T ss_dssp             HHHHTSCCEECSCSSSHHHHHHHHSCCTTEEEECCCGGGSHHHHTEEECTTSCEEECCHHHHHHHHHHHHHTCSEEEECC
T ss_pred             HHHhCCEEEEccccCCHHHHHHhhCCCCCCEEEeeccccchhhcCCCCCCCcccccCCHHHHHHHHHHHHhccccEeecc
Confidence            99998779999999998888888999999999999999999776331100011101111224679999999999999999


Q NP_000282.1     166 FGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFL  245 (417)
Q Consensus       166 Fg~aHR~~aS~~gi~l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a~tfl  245 (417)
                      |+++||.|||++++++|+++||++|++||++|.+++++|+||+++|+||+|++||+++|++|+++||.|++||+|||+||
T Consensus       162 F~~~HR~hAS~vgi~lp~~~aG~l~~kEi~~L~~~~~~p~rP~v~IlGGaKv~dKi~li~~Ll~~~D~IliGG~~a~tFL  241 (413)
T 1HDI_A          162 FGTAHRAHSSMVGVNLPKKAGAFLMKKELNYFAAAAESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFL  241 (413)
T ss_dssp             GGGTTCCCHHHHCCCCSCEEECHHHHHHHHHHHHHHTSCCSSEEEEECCSCSGGGHHHHHHHHTTCSEEEECGGGHHHHC
T ss_pred             cccCCCCCCCccccCCchhHHHHHHHHHHHHHHHHHhCCCCCEEEEEcCCCHHHHHHHHHHHHHcCCEEEECchHHHHHH
Confidence            99999999999999986579999999999999999999999999999999999999999999999999999999999999


Q NP_000282.1     246 KVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYA  325 (417)
Q Consensus       246 ~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti~~~~  325 (417)
                      +|++++++|+|++|++..+.|++++++|+.++++|++|+|++|.+.+..+...........+|++|+++||||+|++.|+
T Consensus       242 ~a~g~~~iG~Sl~e~~~~~~a~~il~~a~~~~~ki~lP~D~vv~~~~~~~~~~~~~~~~~~ip~~~~ilDIGp~Ti~~~~  321 (413)
T 1HDI_A          242 KVLNNMEIGTSLFDEAGKKIVKNLMSKAAANGVKITLPVDFVTADKFDEQAKIGQATVASGIPAGWMGLDCGPKSSAKYS  321 (413)
T ss_dssp             CCCCCCCBTTCCCCTTGGGTHHHHHHHHHHHTCEEECCCEEEEESSSSTTCCEEEEETTTCBCTTCEEEEECHHHHHHHH
T ss_pred             HHhCCCcccceeechhHHHHHHHHHHHHHHCCCeEEceeeEEeccccchhcccceeeecCCCCCCcccccCCHHHHHHHH
Confidence            99855689999999999999999999988999999999999999875432211111112378899999999999999999


Q NP_000282.1     326 EAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEG  405 (417)
Q Consensus       326 ~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le~L~G  405 (417)
                      ++|++|||||||||||+||.++|++||+++++++++++++++++|+|||||+++++++|+.++++||||||||+||||+|
T Consensus       322 ~~I~~aktI~wnGP~G~~E~~~f~~GT~~ia~~i~~~~~~~a~sivGGGdT~~~~~~~g~~~~~~~vSTGGGA~Le~L~g  401 (413)
T 1HDI_A          322 EAVARAKQIVWNGPVGVFEWEAFAQGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDNVSHVSTGGGASLELLEG  401 (413)
T ss_dssp             HHHHHCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHHHHTTCEEEECTTHHHHHHHHTTCTTTSSEECSCHHHHHHHHTT
T ss_pred             HHHHhCCEEEEeCCCCcccchhhchHHHHHHHHHHHHhcCCcEEEEecccHHHHHHHcCCCCCCEEEecChHHHHHHHcC
Confidence            99999999999999999988789999999999997632247899999999999888888888899999999999999999


Q NP_000282.1     406 KVLPGVDALSNI  417 (417)
Q Consensus       406 ~~LPgl~aL~~~  417 (417)
                      +.||||++|+++
T Consensus       402 k~LPgi~aL~~~  413 (413)
T 1HDI_A          402 KVLPGVDALSNV  413 (413)
T ss_dssp             CCCHHHHTSCBC
T ss_pred             CCCchHHHhhcC
Confidence            999999999874


No 3
>6Y3A_A Phosphoglycerate kinase (E.C.2.7.2.3); phosphoglycerate kinase, metabolic enzyme, kinase; 1.49A {Plasmodium vivax}
Probab=100.00  E-value=2.6e-112  Score=865.36  Aligned_cols=414  Identities=59%  Similarity=0.970  Sum_probs=363.7  Template_Neff=6.300

Q NP_000282.1       2 SLSNKLTLDKL-DVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEP   80 (417)
Q Consensus         2 ~~~~~~~i~~~-~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~   80 (417)
                      ++.+++++.|. |++|||||||+|+|||+++++|.|++||++++|||+||+++||++|||+||+|||+++. .+++||+|
T Consensus         9 ~~~~~~~~~~~~~l~gK~vlvRvD~NVPl~~~~i~dd~RI~~~lpTI~~Ll~~gak~vil~sHlGRP~g~~-~~~~Sl~p   87 (424)
T 6Y3A_A            9 SLGNKLSITDVKAIQGKKVLVRVDFNVPIENGVIKDTNRITATLPTIHHLKKEGAAKIILISHCGRPDGTK-NLKYTLKP   87 (424)
T ss_dssp             CCTTBCBGGGCCCCTTCEEEEECCCCCCEETTEESCCHHHHTTHHHHHHHHHTTCSEEEEECCCSCCTTSC-CGGGCSHH
T ss_pred             cCCCCccccchHHhCCCEEEEEeecCCcccCCccCCChHHHhHHHHHHHHHHCCCCEEEEEeeCCCCCCCc-cccccHHH
Confidence            46788999997 89999999999999999888999999999999999999999994499999999998764 56899999


Q NP_000282.1      81 VAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDV  160 (417)
Q Consensus        81 va~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Di  160 (417)
                      |+++|+++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|+++++++++|+.++..+++.+|+++||+++|+
T Consensus        88 va~~L~~~l~~~v~f~~d~~g~~~~~~i~~~~~g~illLENlRF~~~E~~~~~~~~~n~~~~~~~~~~~fa~~LA~l~Di  167 (424)
T 6Y3A_A           88 VAETLGTLLGEEVLFLSDCVGEEVAAQINQAKDNSVILLENLRFHVEEEGKGVDAAGNKIKASKEDMEKFQNELTKLGDV  167 (424)
T ss_dssp             HHHHHHHHHTSCCEECSCSSSHHHHHHHHHSCTTEEEECCCGGGSHHHHSEEECTTSCEEECCHHHHHHHHHHHHTTCSE
T ss_pred             HHHHHHHHhCCEEEeccccCCHHHHHHHHhccCCCEEEeccccccchhccCCccccccccccCHHHHHHHHHHHhhccCe
Confidence            99999999987799999999988888889999999999999999987753211101121111122346799999999999


Q NP_000282.1     161 YVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM  240 (417)
Q Consensus       161 yVNDAFg~aHR~~aS~~gi~l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~  240 (417)
                      |||||||++||.|||+++++.+.++||++|++||++|++++++|+||+++|+||+|++||+++|++|+++||.|++||+|
T Consensus       168 yVNDAF~~~HR~hAS~vgi~~~~s~aG~llekEl~~L~k~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~vD~IligG~~  247 (424)
T 6Y3A_A          168 FINDAFGTAHRAHSSMVGIKMNVKASGFLMKKELEYFSKALENPQRPLLAILGGAKVSDKIQLIKNLLDKVDKMIIGGGM  247 (424)
T ss_dssp             EEECCGGGTTSCCHHHHCCCCSCEEECHHHHHHHHHHHHHHTSCCSSEEEEEECSCSGGGHHHHHHHHTTCSEEEEESTH
T ss_pred             EEecccccCccccCcchHHhccHHHhcHHHHHHHHHHHHHHhCCCCCEEEEEcCCCHHHHHHHHHHHHHcCCEEEECcHH
Confidence            99999999999999999999322899999999999999999999999999999999999999999999989999999999


Q NP_000282.1     241 AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPES  320 (417)
Q Consensus       241 a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~T  320 (417)
                      ||+||+|++++++|+|++|++..+.|++++++|+.++++|++|+|++|.+.+..+.....+.....+|++|+++||||+|
T Consensus       248 a~tfL~a~~~~~ig~s~~e~~~~~~a~~il~~a~~~~~ki~lP~D~vv~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~T  327 (424)
T 6Y3A_A          248 AYTFKYVLNNMKIGDSLFDEAGSKIVNEIMEKAKAKNVEIYLPVDFKVADKFDNNANTKVVTDEEGIEDKWMGLDAGPKS  327 (424)
T ss_dssp             HHHHHHHHHCCCBTTSCCCHHHHTTHHHHHHHHHHTTCEEECCSEEEEESSSSTTSCEEEEETTTCBCTTCEEEEECHHH
T ss_pred             HHHHHHHHCCCcccchhccchhHHHHHHHHHHHHHCCCeEEeeeeeeeccccCCCCCceEecCccCCCCCcccccCCHHH
Confidence            99999997455799999999889999999999989999999999999998753322111122224788999999999999


Q NP_000282.1     321 SKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASL  400 (417)
Q Consensus       321 i~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~L  400 (417)
                      ++.|.+.|++|||||||||||+||.++|++||+++++++++++++++++|+|||||+++++++|+.++++||||||||+|
T Consensus       328 i~~~~~~I~~aktI~wNGP~G~~E~e~f~~GT~~ia~al~~~~~~~a~~ivGGGdT~~~~~~~g~~~~~s~vSTGGGA~L  407 (424)
T 6Y3A_A          328 IENYKDVILSSKTIIWNGPQGVFEMPNFAKGSIECLNLVIEATKKGAISIVGGGDTASLVEQQQKKNEISHVSTGGGASL  407 (424)
T ss_dssp             HHHHHHHHHTCSEEEEESCSBCTTSGGGCHHHHHHHHHHHHHHHTTCEEEECSHHHHHHHHHTTCGGGSSEECCCTHHHH
T ss_pred             HHHHHHHHHhCCEEEEeCCCCcccCCCcchhHHHHHHHHHHHhcCCCEEEEechHHHHHHHHhccccCcEEEEechhHHH
Confidence            99999999999999999999999988899999999999976322478999999999999988888788999999999999


Q NP_000282.1     401 ELLEGKVLPGVDALSN  416 (417)
Q Consensus       401 e~L~G~~LPgl~aL~~  416 (417)
                      |||+|+.||||++|++
T Consensus       408 e~L~G~~LPgieaL~~  423 (424)
T 6Y3A_A          408 ELLEGKELPGVVALSS  423 (424)
T ss_dssp             HHHTTCCCHHHHTSCB
T ss_pred             HHHcCCCCChhHHhhc
Confidence            9999999999999975


No 4
>3UWD_A Phosphoglycerate kinase (E.C.2.7.2.3); Anthrax, Structural Genomics, Center for; HET: BTB, MSE; 1.68A {Bacillus anthracis}
Probab=100.00  E-value=6.9e-112  Score=855.65  Aligned_cols=391  Identities=48%  Similarity=0.845  Sum_probs=357.0  Template_Neff=6.400

Q NP_000282.1       4 SNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAV   83 (417)
Q Consensus         4 ~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~   83 (417)
                      |++++++|.|++|||||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++. .+.+||+||++
T Consensus         1 ~~~~~l~~~~l~gK~vlvR~D~NVPi~~~~i~dd~RI~~~lpTI~~L~~~ga-kvil~sHlGrP~g~~-~~~~sl~~va~   78 (394)
T 3UWD_A            1 MNKKSIRDVDLKGKRVFCRVDFNVPMKEGKITDETRIRAALPTIQYLVEQGA-KVILASHLGRPKGQA-VEELRLTPVAA   78 (394)
T ss_dssp             CCBCBGGGSCCTTCEEEEECCCCCCC--CCCCCCHHHHHTHHHHHHHHHTTC-EEEEECCCSCCTTSC-CGGGCSHHHHH
T ss_pred             CCCccccccccCCCEEEEEeecCccccCCCcCCcHHHHHHHHHHHHHHHCCC-cEEEEeccCCCCCcc-chhhChHHHHH
Confidence            4567888888999999999999999987899999999999999999999999 599999999999864 56899999999


Q NP_000282.1      84 ELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVN  163 (417)
Q Consensus        84 ~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVN  163 (417)
                      +|+++|+.+|.|+++|+|+++++.++.+++|+|+||||+|||++|+++               +.+|++.||+++|+|||
T Consensus        79 ~L~~~l~~~v~f~~~~~g~~~~~~i~~~~~g~i~lLENlRf~~~E~~n---------------d~~fa~~La~l~DiyVn  143 (394)
T 3UWD_A           79 RLGELLGKDVKKADEAFGPVAQEMVAAMNEGDVLVLENVRFYAGEEKN---------------DAELAKEFAALADIFVN  143 (394)
T ss_dssp             HHHHHHTSCCEECSCSSSHHHHHHHHTCCTTCEEECCCGGGSHHHHHT---------------CHHHHHHHHTTCSEEEE
T ss_pred             HHHHHHCCEEeecCccccHHHHHHHHHccCCCEEEEecccccCccccc---------------cHHHHHHHHHhccHHHh
Confidence            999999877999999999888888899999999999999999876532               36799999999999999


Q NP_000282.1     164 DAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMA  241 (417)
Q Consensus       164 DAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a  241 (417)
                      ||||++||.|||+++++  +| ++||++|++|+++|++++++|+||+++|+||+|++||+++|++|+++||.|++||+||
T Consensus       144 DAF~~~HR~hAS~~gi~~~lp-s~aG~ll~kEl~~L~~~~~~p~~P~v~IlGGaKv~dKi~~i~~Ll~~~d~iligG~~a  222 (394)
T 3UWD_A          144 DAFGAAHRAHASTAGIADYLP-AVSGLLMEKELEVLGKALSNPERPFAAIIGGAKVKDKIGLIRHLLDKVDNLIIGGGLA  222 (394)
T ss_dssp             CCGGGTTSCCTTTTGGGGTSC-EEECHHHHHHHHHHHHHHHSCCSSEEEEECSSCHHHHHHHHHHHTTTCSEEEECSTTH
T ss_pred             ccHhHhcccccchhhHhhhhH-hhhcHHHHHHHHHHHHHHhCCCCCEEEEECCCCHHHHHHHHHHHHHhCCEEEECChHH
Confidence            99999999999999999  77 8999999999999999999999999999999999999999999999999999999999


Q NP_000282.1     242 FTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESS  321 (417)
Q Consensus       242 ~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  321 (417)
                      |+||+|+ |+++|+|++|++..+.|++++++|+.++++|++|+|++|.+++...+.. .+...+.+|++|+++||||+|+
T Consensus       223 ~tfL~a~-g~~iG~s~~e~~~~~~a~~il~~a~~~~~ki~lP~D~vv~~~~~~~~~~-~~~~~~~i~~~~~~~DIGp~Ti  300 (394)
T 3UWD_A          223 YTFVKAL-GHEIGLSLCEDDKIELAKEFMQLAKEKGVNFYMPVDVVITEEFSETATT-KIVGIDSIPSNWEGVDIGPKTR  300 (394)
T ss_dssp             HHHHHHT-TCCCTTCCCCGGGHHHHHHHHHHHHHHTCEEECCSEEEEESSCSTTCCE-EEEEGGGCCTTCEEEEECHHHH
T ss_pred             HHHHHHh-CCcccccccchHHHHHHHHHHHHHHHcCCeEEceeeEEeccccCcccce-EEeccccCCCCceeecCCHHHH
Confidence            9999998 8999999999999999999999988899999999999999875432211 1222357889999999999999


Q NP_000282.1     322 KKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLE  401 (417)
Q Consensus       322 ~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le  401 (417)
                      +.|.++|++|||||||||||+||.++|++||+++++++++++  ++++|+|||||+++++++|+.++++||||||||+||
T Consensus       301 ~~~~~~I~~aktI~wnGP~G~~E~e~f~~GT~~i~~ai~~~~--~a~~ivGGGdT~~~~~~~g~~~~~s~vSTGGGA~Le  378 (394)
T 3UWD_A          301 EIYADVIKNSKLVVWNGPMGVFEMTPFAEGTKAVGQALADAE--GTYSVIGGGDSAAAVEKFGMADKMSHISTGGGASLE  378 (394)
T ss_dssp             HHHHHHHHTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHCT--TCEEEECSHHHHHHHHHTTCGGGCSEECCCTHHHHH
T ss_pred             HHHHHHHhcCCEEEEECCCCcccCCCcChHHHHHHHHHHHcC--CCeEEEechHHHHHHHHcCCCCcceEEEcccHHHHH
Confidence            999999999999999999999988889999999999997632  689999999999888888888889999999999999


Q NP_000282.1     402 LLEGKVLPGVDALSN  416 (417)
Q Consensus       402 ~L~G~~LPgl~aL~~  416 (417)
                      ||+|++||||++|++
T Consensus       379 ~L~Gk~LPgl~aL~~  393 (394)
T 3UWD_A          379 FMEGKELPGVVCLND  393 (394)
T ss_dssp             HHTTCCCHHHHTSCB
T ss_pred             HHcCCCCCchhhhcc
Confidence            999999999999985


No 5
>1QPG_A 3-PHOSPHOGLYCERATE KINASE, MAGNESIUM-5'-ADENYLY-IMIDO-TRIPHOSPHATE, 3-PHOSPHOGLYCERIC ACID; PHOSPHOTRANSFERASE (CARBOXYL ACCEPTOR), KINASE, GLYCOLYSIS; HET: 3PG, MAP; 2.4A {Saccharomyces cerevisiae} SCOP: c.86.1.1
Probab=100.00  E-value=7.2e-112  Score=861.28  Aligned_cols=413  Identities=66%  Similarity=1.036  Sum_probs=363.5  Template_Neff=6.500

Q NP_000282.1       2 SLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPV   81 (417)
Q Consensus         2 ~~~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~v   81 (417)
                      +..++++++|.|++|||||||+|+|||+++++|.|++||++++|||+||+++||++|||+||+|||+++. ++.+||+||
T Consensus         1 ~~~~~~~i~~~~l~gK~vlvRvD~NVPl~~~~i~dd~RI~~~lpTI~~Ll~~gak~vil~sHlGrP~g~~-~~~~Sl~pv   79 (415)
T 1QPG_A            1 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGQPNGER-NEKYSLAPV   79 (415)
T ss_dssp             CTTSBCBGGGCCCTTCEEEEECCCCCCBSSSSBSCCHHHHHHHHHHHHHHTTCCSEEEEECCCSCCCSSC-CGGGCSHHH
T ss_pred             CCcccccccccccCCCEEEEEEecCCccCCCccCCCHHHHHHHHHHHHHHHcCCCEEEEEeeCCCCCCCc-CcccchHHH
Confidence            3567889998999999999999999999888999999999999999999999994489999999998764 568999999


Q NP_000282.1      82 AVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVY  161 (417)
Q Consensus        82 a~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Diy  161 (417)
                      +++|+++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|+++.++ ++.+.+++.+++.+|+++||+++|+|
T Consensus        80 a~~L~~~l~~~v~f~~d~~g~~~~~~i~~~~~g~illLENlRF~~~E~~~~~~-n~~~~~~~~~~~~~fa~~LA~l~Diy  158 (415)
T 1QPG_A           80 AKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRKV-DGQKVKASKEDVQKFRHELSSLADVY  158 (415)
T ss_dssp             HHHHHHHHTSCCEEESCSSSHHHHHHHHTCCTTEEEEECCGGGSHHHHTEEEE-TTEEEECCHHHHHHHHHHHHHTCSEE
T ss_pred             HHHHHHHhCCeEEEccCCCCHHHHHHHHhCCCCCeEehhhhhhcchhcccccc-CCccccCCHHHHHHHHHHHHhcCCeE
Confidence            99999999877999999999888888899999999999999999877532000 00000111223478999999999999


Q NP_000282.1     162 VNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMA  241 (417)
Q Consensus       162 VNDAFg~aHR~~aS~~gi~l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a  241 (417)
                      ||||||++||.|||++++++|+++||++|++||++|++++++|+||+++|+||+|++||+++|++|+++||.|++||+||
T Consensus       159 VNDAF~~~HR~hAS~vgi~lp~s~aG~ll~kEl~~L~k~l~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~IligG~~a  238 (415)
T 1QPG_A          159 INDAFGTAHRAHSSMVGFDLPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMA  238 (415)
T ss_dssp             EECCGGGTTSCCHHHHCCCCSCEEECHHHHHHHHHHHHHHSSCCSSEEEEECSSCSGGGHHHHHHHTTTCSEEEECGGGH
T ss_pred             eecccccCCcccccceecCCChhhhcHHHHHHHHHHHHHhhCCCCCEEEEEcCCCHHHHHHHHHHHHHhCCEEEECcHHH
Confidence            99999999999999999997658999999999999999999999999999999999999999999999899999999999


Q NP_000282.1     242 FTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESS  321 (417)
Q Consensus       242 ~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  321 (417)
                      |+||+|++++++|+|++|++..+.|++++++|+.++++|+||+|++|.+.+..+.....+...+.+|++|+++||||+|+
T Consensus       239 ~tfL~a~~~~~iG~S~~e~~~~~~a~~il~~a~~~~~ki~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  318 (415)
T 1QPG_A          239 FTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEGIPAGWQGLDNGPESR  318 (415)
T ss_dssp             HHHHHHHSCCCCCSCCCCHHHHHHHHHHHHHHHHHTCEEECCSEEEEESSSSSSCCCCEEETTTCCCTTCEEEEECHHHH
T ss_pred             HHHHHHhCCCcCCccccchhhhhHHHHHHHHHHHcCCeEEeeeeEEEecccCCCCCCceeeccCCCCCCCcccccCHHHH
Confidence            99999975558999999998889999999998899999999999999886532221111112237889999999999999


Q NP_000282.1     322 KKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLE  401 (417)
Q Consensus       322 ~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le  401 (417)
                      +.|.+.|++|||||||||||+||.++|++||+++++++++++++++++|+|||||+++++++|+.++++||||||||+||
T Consensus       319 ~~~~~~i~~aktI~wnGP~G~~E~~~f~~GT~~ia~~i~~~~~~~a~~ivGGGdT~~~~~~~g~~~~~s~vSTgGGA~L~  398 (415)
T 1QPG_A          319 KLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLE  398 (415)
T ss_dssp             HHHHHHHTTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHHHHHTCEEEECCHHHHHHHHHTTCGGGSSEECCCTHHHHH
T ss_pred             HHHHHHHHcCCEEEEcCCCChhcccccChHHHHHHHHHHHHhcCCCeEEEEehHHHHHHHHcCCCCccEEEEcCchHHHH
Confidence            99999999999999999999999888999999999999763224789999999999999888987889999999999999


Q NP_000282.1     402 LLEGKVLPGVDALSN  416 (417)
Q Consensus       402 ~L~G~~LPgl~aL~~  416 (417)
                      ||+|+.||||++|++
T Consensus       399 ~L~G~~LPgieaL~~  413 (415)
T 1QPG_A          399 LLEGKELPGVAFLSE  413 (415)
T ss_dssp             HHTSCCCHHHHTSCB
T ss_pred             HHcCCCCChHHHHhh
Confidence            999999999999975


No 6
>3PGK_A PHOSPHOGLYCERATE KINASE (E.C.2.7.2.3); PHOSPHOTRANSFERASE(CARBOXYL AS ACCEPTOR), TRANSFERASE; HET: ATP, 3PG; 2.5A {Saccharomyces cerevisiae} SCOP: c.86.1.1
Probab=100.00  E-value=7.8e-112  Score=861.30  Aligned_cols=413  Identities=64%  Similarity=1.016  Sum_probs=363.8  Template_Neff=6.500

Q NP_000282.1       2 SLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPV   81 (417)
Q Consensus         2 ~~~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~v   81 (417)
                      +..++++++|.|++|||||||+|+|||+++++|.|++||++++|||+||+++||++|||+||+|||+++. ++.+||+||
T Consensus         2 ~~~~~~~~~~~~l~gK~vlvRvD~NVPl~~~~i~dd~RI~~~lpTI~~Ll~~gak~vil~sHlGRP~g~~-~~~~Sl~pv   80 (416)
T 3PGK_A            2 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRPNGER-NEKYSLAPV   80 (416)
T ss_dssp             CCCCSCCSSCCCCSSCCEEEECCCCCCCSSSCCSCCHHHHHHHHHHHHHHHHCCSCCEEECCCCCCCSSS-SCSCCSHHH
T ss_pred             CCcccccccccccCCCEEEEEEecCCccCCCccCCCHHHHHHHHHHHHHHHcCCCEEEEEeecCCCCCCc-CcccChHHH
Confidence            5678899999999999999999999999888999999999999999999999994489999999998764 568999999


Q NP_000282.1      82 AVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVY  161 (417)
Q Consensus        82 a~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Diy  161 (417)
                      +++|+++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|+++.++ ++.+.+++.+++.+|++.||+++|+|
T Consensus        81 a~~L~~~l~~~v~f~~d~~g~~~~~~i~~~~~g~i~lLENlRF~~~E~~~~~~-n~~~~~~~~~~~~~fa~~La~l~diy  159 (416)
T 3PGK_A           81 AKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRKV-DGQKVKASKEDVQKFRHELSSLADVY  159 (416)
T ss_dssp             HHHHHHHHCSCEECCCSSCCHHHHHHHHHSSSCEEEECSSCSSCSSCCCCSSS-SSSSCCCCCHHHHHHHHHHHTSCSEE
T ss_pred             HHHHHHHHCCeeEEcccCCCHHHHHHHHhCCCCCeEehhhhhhcchhcccccc-CCcccccCHHHHHHHHHHHHhcCCeE
Confidence            99999999877999999999888888899999999999999999877522000 00001111223477999999999999


Q NP_000282.1     162 VNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMA  241 (417)
Q Consensus       162 VNDAFg~aHR~~aS~~gi~l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a  241 (417)
                      ||||||++||.|||++++++|+++||++|++||++|.+++++|+||+++|+||+|++||+++|++|+++||.|++||+||
T Consensus       160 VNDAF~~~HR~hAS~vgi~lp~s~aG~ll~kEl~~L~k~l~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~iligG~~a  239 (416)
T 3PGK_A          160 INDAFGTAHRAHSSMVGFDLPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMA  239 (416)
T ss_dssp             EECSSCSSSSCCTTSSSCCSSCEEECHHHHHHHHHHHHHTSCCSSCBEEEECSSCCSTHHHHHHHHHSSSSCEEEECCHH
T ss_pred             eecccccCCccccCccccCCchhhhcHHHHHHHHHHHHHhhCCCCCEEEEEcCCCHHHHHHHHHHHHHhCCEEEeCcHHH
Confidence            99999999999999999997658999999999999999999999999999999999999999999999899999999999


Q NP_000282.1     242 FTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESS  321 (417)
Q Consensus       242 ~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  321 (417)
                      |+||+|++++++|+|++|++..+.|++++++|+.++++|+||+|++|.+.+........+...+.+|++|+++||||+|+
T Consensus       240 ~tfL~a~~~~~iG~s~~e~~~~~~a~~il~~a~~~~~kI~LP~D~vv~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  319 (416)
T 3PGK_A          240 FTFKKVLENTEIGDSIFDKAVGPEIAKLMEKAKAKGVEVVLPVDFIIADAFSASANTKTVTDKEGIPAGWQGLDNGPESR  319 (416)
T ss_dssp             HHHHHSSHHHHHHCSCSCTTHHHHHHHHHHHHHHHTCEECCCSEEEECSSSSSSSCEEEESSCCSSSCSSCCCSCCHHHH
T ss_pred             HHHHHHhCCCccCcchhcccchHHHHHHHHHHHHcCCeEEccccEEEeccccccCCcceeecccCCCCCCccccCCHHHH
Confidence            99999975568999999998889999999988889999999999999886532221111112237888999999999999


Q NP_000282.1     322 KKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLE  401 (417)
Q Consensus       322 ~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le  401 (417)
                      +.|.+.|++|||||||||||+||.++|++||+++++++++++++++++|+|||||+++++++|+.++++||||||||+||
T Consensus       320 ~~~~~~i~~aktI~wnGP~G~~E~~~f~~GT~~ia~~i~~~~~~~a~~ivGGGdT~~~~~~~g~~~~~s~vSTGGGA~L~  399 (416)
T 3PGK_A          320 KLFAATVAKATVILWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLE  399 (416)
T ss_dssp             HHHHHHHSSCSBEEECSCSSCTTSTTSSSHHHHHHHHHHHHTTSSCCEEECSSHHHHHHHHHCCTTCCEECCCSHHHHHH
T ss_pred             HHHHHHHHhCCEEEEeCCCChhhccccchHHHHHHHHHHHHccCCCeEEEEehhHHHHHHHcCCCCcceEEecChhHHHH
Confidence            99999999999999999999999888999999999999763224789999999999999888987889999999999999


Q NP_000282.1     402 LLEGKVLPGVDALSN  416 (417)
Q Consensus       402 ~L~G~~LPgl~aL~~  416 (417)
                      ||+|+.||||++|++
T Consensus       400 ~L~Gk~LPgl~aL~~  414 (416)
T 3PGK_A          400 LLEGKELPGVAFLSE  414 (416)
T ss_dssp             HHHTCCCHHHHHCSS
T ss_pred             HHcCCCCChHHHHhc
Confidence            999999999999975


No 7
>3Q3V_A Phosphoglycerate kinase (E.C.2.7.2.3); Structural Genomics, Center for Structural; HET: SO4, FMT, PGE; 2.145A {Campylobacter jejuni subsp. jejuni NCTC 11168}
Probab=100.00  E-value=3.2e-111  Score=852.34  Aligned_cols=392  Identities=45%  Similarity=0.820  Sum_probs=356.7  Template_Neff=6.300

Q NP_000282.1       2 SLSNKLTLDKLDVKGKRVVMRVDFNVPMKN-NQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEP   80 (417)
Q Consensus         2 ~~~~~~~i~~~~l~gK~VlvRvD~NVPl~~-~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~   80 (417)
                      +|+++++++|.|++|||||||+|+|||+++ ++|.|++||++++|||+||+++|| +|||+||+|||+++  ++.+||+|
T Consensus         3 ~~~~~~~l~~~~l~gK~vlvR~D~NVPi~~~~~i~dd~RI~~~lpTI~~Ll~~ga-~vil~sHlGrP~~~--~~~~Sl~~   79 (403)
T 3Q3V_A            3 AMSDIISIKDIDLAKKKVFIRCDFNVPQDDFLNITDDRRIRSAIPTIRYCLDNGC-SVILASHLGRPKEI--SSKYSLEP   79 (403)
T ss_dssp             ---CBCBGGGSCCTTCEEEEECCCCCCBCTTCCBSCCHHHHHHHHHHHHHHHTTC-EEEEECCCSCCSSC--CGGGCSHH
T ss_pred             cccccccccchhcCCCEEEEEeecCCCcccCCccCCChHHHHHHHHHHHHHHCCC-EEEEEecCCCCccc--CcccCHHH
Confidence            578899999889999999999999999975 489999999999999999999999 59999999999865  35899999


Q NP_000282.1      81 VAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDV  160 (417)
Q Consensus        81 va~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Di  160 (417)
                      |+++|+++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|+++               +.+|++.||+++|+
T Consensus        80 va~~L~~~l~~~V~f~~~~~g~~~~~~i~~~~~g~i~lLENlRF~~~E~~n---------------~~~fa~~La~l~Di  144 (403)
T 3Q3V_A           80 VAKRLARLLDKEIVMAKDVIGEDAKTKAMNLKAGEILLLENLRFEKGETKN---------------DENLAKELASMVQV  144 (403)
T ss_dssp             HHHHHHHHHTSCCEECSSSSSHHHHHHHHHCCTTCEEECSCGGGSTTGGGT---------------CHHHHHHHHHTCSE
T ss_pred             HHHHHHHHhCCeeeecCCCCCHHHHHHHHhccCCCEEEEcccccCCcccCC---------------CHHHHHHHHhhchH
Confidence            999999999877999999999888888889999999999999999876422               36799999999999


Q NP_000282.1     161 YVNDAFGTAHRAHSSMVGVN--LPQ--KAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMII  236 (417)
Q Consensus       161 yVNDAFg~aHR~~aS~~gi~--l~~--~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~ili  236 (417)
                      |||||||++||.|||+++++  +|+  ++||++|++||++|++++++|+||+++|+||+|++||+++|++|+++||.|+|
T Consensus       145 yVNDAF~~~HR~hAS~vgi~~~lp~~~s~aG~ll~kEl~~L~~~~~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~ili  224 (403)
T 3Q3V_A          145 YINDAFGVCHRAHSSVEAITKFFDEKHKGAGFLLQKEIDFASNLIKHPARPFVAVVGGSKVSGKLQALTNLLPKVDKLII  224 (403)
T ss_dssp             EEECCGGGTTSCCTTTTGGGGGSCTTSEEECHHHHHHHHHHHHHTTCCCSSEEEEECSSCHHHHHHHHHHHTTTCSEEEE
T ss_pred             HHhcccccccccCcchhHHHhhcccccccccHHHHHHHHHHHHHHhCCCCCEEEEECCCcHHHHHHHHHHHHHhCCEEEE
Confidence            99999999999999999998  663  79999999999999999999999999999999999999999999999999999


Q NP_000282.1     237 GGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDC  316 (417)
Q Consensus       237 gG~~a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DI  316 (417)
                      ||+|||+||+|+ |+++|+|++|++..+.|++++++|++++++|++|+|++|.+++..++.. ...+...+|++|+++||
T Consensus       225 gG~~a~tfL~a~-g~~iG~s~~e~~~~~~a~~il~~a~~~~~kI~lP~D~vv~~~~~~~~~~-~~~~~~~i~~~~~~~DI  302 (403)
T 3Q3V_A          225 GGGMAFTFLKAL-GYDIGNSLLEEELLEEANKILTKGKNLGVKIYLPVDVVAAPACSQDVPM-KFVPAQEIPNGWMGLDI  302 (403)
T ss_dssp             CSTTHHHHHHHT-TCCCTTSCCCGGGHHHHHHHHHHHHHTTCEEECCSEEEEESSSSTTSCC-EEEEGGGCCTTCEEEEE
T ss_pred             cchHHHHHHHHc-CCCCccchhhHHHHHHHHHHHHHHHHhCCeeEeeccEEecCcCCCCCCc-eeechhhcCCCccCccC
Confidence            999999999998 8999999999999999999999998999999999999999865322211 11122478889999999


Q NP_000282.1     317 GPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGG  396 (417)
Q Consensus       317 Gp~Ti~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgG  396 (417)
                      ||+|++.|.+.|++|||||||||||+||+++|++||+++++++++.   ++++|+|||||+++++++|+.++++||||||
T Consensus       303 Gp~Ti~~~~~~i~~aktI~wnGp~G~~E~e~f~~GT~~i~~~i~~~---~a~~ivGGGdT~~~~~~~g~~~~~~~vStGG  379 (403)
T 3Q3V_A          303 GPASVRLFKEVISDAQTIWWNGPMGVFEIDKFSKGSIKMSHYISEG---HATSVVGGGDTADVVARAGDADEMTFISTGG  379 (403)
T ss_dssp             CHHHHHHHHHHHTTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHS---SSEEEEESHHHHHHHHHTTCGGGSSEECCCH
T ss_pred             CHHHHHHHHHHHhhCCEEEEeCCCCcccccccchHHHHHHHHHHhC---CCeEEEeCHHHHHHHHHcCCCccccEEecch
Confidence            9999999999999999999999999999878999999999999762   6899999999999999889888899999999


Q NP_000282.1     397 GASLELLEGKVLPGVDALSN  416 (417)
Q Consensus       397 gA~Le~L~G~~LPgl~aL~~  416 (417)
                      ||+||||+|++||||++|++
T Consensus       380 GA~Le~L~Gk~LPgi~aL~~  399 (403)
T 3Q3V_A          380 GASLELIEGKELPGVKALRS  399 (403)
T ss_dssp             HHHHHHHTTCCCHHHHTTBC
T ss_pred             HHHHHHHcCCCCchHHHHhh
Confidence            99999999999999999975


No 8
>1PHP_A 3-PHOSPHOGLYCERATE KINASE (PGK) (E.C.2.7.2.3); KINASE; HET: ADP; 1.65A {Geobacillus stearothermophilus} SCOP: c.86.1.1
Probab=100.00  E-value=1.1e-110  Score=847.59  Aligned_cols=387  Identities=48%  Similarity=0.853  Sum_probs=355.2  Template_Neff=6.500

Q NP_000282.1       8 TLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKS   87 (417)
Q Consensus         8 ~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~~L~~   87 (417)
                      +++|.|++|||||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++. .+.+||+||+++|++
T Consensus         5 ~l~~~~l~gK~vl~R~D~NVpi~~~~i~d~~RI~~~lpTI~~Ll~~ga-kvvl~sHlGrP~g~~-~~~~Sl~~va~~L~~   82 (394)
T 1PHP_A            5 TIRDVDVRGKRVFCRVDFNVPMEQGAITDDTRIRAALPTIRYLIEHGA-KVILASHLGRPKGKV-VEELRLDAVAKRLGE   82 (394)
T ss_dssp             BGGGSCCTTCEEEEECCCCCCEETTEESCCHHHHHHHHHHHHHHHTTC-EEEEECCCSCCCSSC-CGGGCSHHHHHHHHH
T ss_pred             cccccccCCCEEEEEeecCCcccCCCCCCcHHHHHHHHHHHHHHHCCC-cEEEEeccCCCCCCc-chhhhHHHHHHHHHH
Confidence            777788999999999999999988899999999999999999999999 599999999998764 468999999999999


Q NP_000282.1      88 LLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFG  167 (417)
Q Consensus        88 ~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVNDAFg  167 (417)
                      +|+.+|.|+++|+|+++++.++.+++|+|+||||+|||++|+++               +.+|++.||+++|+|||||||
T Consensus        83 ~l~~~v~f~~~~~g~~~~~~i~~~~~g~illLENlRf~~~E~~n---------------~~~fa~~La~l~DiyVnDAF~  147 (394)
T 1PHP_A           83 LLERPVAKTNEAVGDEVKAAVDRLNEGDVLLLENVRFYPGEEKN---------------DPELAKAFAELADLYVNDAFG  147 (394)
T ss_dssp             HHTSCCEECSCSSSHHHHHHHHTCCTTCEEECCCGGGSHHHHHT---------------CHHHHHHHHTTCSEEEECCGG
T ss_pred             HhCCCeeecCCCCCHHHHHHHHhccCCCEEEeecccCCCccccC---------------CHHHHHHHHHhccHHHccchh
Confidence            99877999999999888888899999999999999999866432               367999999999999999999


Q NP_000282.1     168 TAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFL  245 (417)
Q Consensus       168 ~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a~tfl  245 (417)
                      ++||.|||+++++  +| ++||++|++|+++|++++++|+||+++|+||+|++||+++|++|+++||.|++||+|||+||
T Consensus       148 ~~HR~hAS~vgi~~~lp-s~aG~ll~kEl~~L~~~l~~p~rP~v~IlGGaKv~dKi~~i~~ll~~~d~iligG~~a~tfL  226 (394)
T 1PHP_A          148 AAHRAHASTEGIAHYLP-AVAGFLMEKELEVLGKALSNPDRPFTAIIGGAKVKDKIGVIDNLLEKVDNLIIGGGLAYTFV  226 (394)
T ss_dssp             GTTSCCTTTTGGGGTSC-EEECHHHHHHHHHHHHHHHSCCSSEEEEECSSCHHHHHHHHHHHTTTCSEEEECTTHHHHHH
T ss_pred             HhccccchhhhHHhhhh-hhhcHHHHHHHHHHHHHHhCCCCCEEEEEcCCCHHHHHHHHHHHHhhcCeEEEcchHHHHHH
Confidence            9999999999999  67 89999999999999999999999999999999999999999999998999999999999999


Q NP_000282.1     246 KVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYA  325 (417)
Q Consensus       246 ~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti~~~~  325 (417)
                      +|+ |+++|+|++|++..+.|++++++|+.++++|++|+|++|.+.+..++.. ...+.+.+|++|+++||||+|++.|+
T Consensus       227 ~a~-g~~iG~s~~e~~~~~~a~~il~~a~~~~~ki~lP~D~vv~~~~~~~~~~-~~~~~~~i~~~~~~~DIGp~Ti~~~~  304 (394)
T 1PHP_A          227 KAL-GHDVGKSLLEEDKIELAKSFMEKAKEKGVRFYMPVDVVVADRFANDANT-KVVPIDAIPADWSALDIGPKTRELYR  304 (394)
T ss_dssp             HHT-TCCCTTSCCCGGGHHHHHHHHHHHHHHTCEEECCSEEEEESSSSTTSCE-EEEEGGGCCTTCEEEEECHHHHHHHH
T ss_pred             HHh-CCCCCcccccHhHHHHHHHHHHHHHHcCCEEEceeeEEEeccccccCCc-eEeecCcCCCCcccccCCHHHHHHHH
Confidence            998 8999999999999999999999988899999999999998865322211 11122478899999999999999999


Q NP_000282.1     326 EAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEG  405 (417)
Q Consensus       326 ~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le~L~G  405 (417)
                      ++|++|||||||||||+||.++|++||+++++++++++  ++++|+|||||+++++++++.++++||||||||+||||+|
T Consensus       305 ~~i~~aktI~wnGP~G~~E~~~f~~GT~~i~~~i~~~~--~a~~viGGGdT~~~~~~~~~~~~~~~vStgGGA~Le~L~G  382 (394)
T 1PHP_A          305 DVIRESKLVVWNGPMGVFEMDAFAHGTKAIAEALAEAL--DTYSVIGGGDSAAAVEKFGLADKMDHISTGGGASLEFMEG  382 (394)
T ss_dssp             HHHHTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHCT--TCEEEECSHHHHHHHHHTTCGGGSSEECSCTHHHHHHHTT
T ss_pred             HHHHhCCEEEEeCCCCccccchhchHHHHHHHHHHHhc--CCcEEEechHHHHHHHHcCCCccCeEEecchhHHHHHHcC
Confidence            99999999999999999998889999999999997632  7899999999998888888877899999999999999999


Q NP_000282.1     406 KVLPGVDALSN  416 (417)
Q Consensus       406 ~~LPgl~aL~~  416 (417)
                      +.||||++|++
T Consensus       383 ~~LPgl~aL~~  393 (394)
T 1PHP_A          383 KQLPGVVALED  393 (394)
T ss_dssp             CCCHHHHTSCB
T ss_pred             CCCChhHHhhc
Confidence            99999999975


No 9
>1VPE_A PHOSPHOGLYCERATE KINASE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER; TRANSFERASE, PHOSPHOGLYCERATE KINASE, THERMOTOGA MARITIMA; HET: 3PG, ANP; 2.0A {Thermotoga maritima} SCOP: c.86.1.1
Probab=100.00  E-value=1.1e-110  Score=848.42  Aligned_cols=392  Identities=49%  Similarity=0.875  Sum_probs=356.6  Template_Neff=6.500

Q NP_000282.1       6 KLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVEL   85 (417)
Q Consensus         6 ~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~~L   85 (417)
                      |+++++.|++|||||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++. ++.+||+||+++|
T Consensus         2 ~~~l~~~~l~gK~vl~R~D~NVP~~~~~i~dd~Ri~~~lpTI~~Ll~~ga-~vil~sHlGrP~g~~-~~~~Sl~~v~~~L   79 (398)
T 1VPE_A            2 KMTIRDVDLKGKRVIMRVDFNVPVKDGVVQDDTRIRAALPTIKYALEQGA-KVILLSHLGRPKGEP-SPEFSLAPVAKRL   79 (398)
T ss_dssp             BCBGGGSCCTTCEEEEECCCCCCEETTEESCCHHHHHHHHHHHHHHHTTC-EEEEECCCSCCCSSC-CGGGCSHHHHHHH
T ss_pred             CccccccccCCCEEEEEeeCCcccCCCccCCcHHHHHHHHHHHHHHHCCC-cEEEEeccCCCCCCC-CcccCHHHHHHHH
Confidence            56777788999999999999999988899999999999999999999999 599999999998764 4689999999999


Q NP_000282.1      86 KSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDA  165 (417)
Q Consensus        86 ~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVNDA  165 (417)
                      +++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|+++               +.+|++.||+++|+|||||
T Consensus        80 ~~~l~~~V~f~~~~~g~~~~~~i~~~~~g~i~lLENlRf~~~E~~n---------------~~~fa~~La~l~DiyVnDA  144 (398)
T 1VPE_A           80 SELLGKEVKFVPAVVGDEVKKAVEELKEGEVLLLENTRFHPGETKN---------------DPELAKFWASLADIHVNDA  144 (398)
T ss_dssp             HHHHTSCCEEESCSSSHHHHHHHHTCCTTEEEEECCGGGSTHHHHT---------------CHHHHHHHHTTCSEEEECC
T ss_pred             HHHhCCceeecCCccCHHHHHHHHHhhCCCEEEeeccccCCccccC---------------CHHHHHHHHhcccceeecc
Confidence            9999877999999999888888889999999999999999876422               3679999999999999999


Q NP_000282.1     166 FGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFT  243 (417)
Q Consensus       166 Fg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a~t  243 (417)
                      |+++||.|||+++++  +| ++||++|++|+++|.+++++|+||+++|+||+|++||+++|++|++++|.|++||+||++
T Consensus       145 F~~~HR~~aS~vgi~~~lp-s~aG~l~~kEl~~L~~~~~~p~~P~v~IlGGaKv~dKi~~i~~ll~k~d~iligG~la~t  223 (398)
T 1VPE_A          145 FGTAHRAHASNVGIAQFIP-SVAGFLMEKEIKFLSKVTYNPEKPYVVVLGGAKVSDKIGVITNLMEKADRILIGGAMMFT  223 (398)
T ss_dssp             GGGTTSCCTTTTGGGGTSC-EEECHHHHHHHHHHHHHHHCCCSSEEEEECSSCHHHHHHHHHHHTTTCSEEEECTTTHHH
T ss_pred             hhcCCCCcccchHHHhhch-HhhHHHHHHHHHHHHHHhcCCCCCEEEEEcCCCHHHHHHHHHHHHHHCCEEEECchHHHH
Confidence            999999999999998  66 899999999999999999999999999999999999999999999988999999999999


Q NP_000282.1     244 FLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKK  323 (417)
Q Consensus       244 fl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti~~  323 (417)
                      ||+|+ |+++|+|++|++..+.|++++++|++++++|+||+|++|.+++..+.....+...+.+|++|+++||||+|++.
T Consensus       224 fl~a~-g~~vG~S~~e~~~~~~a~~il~~a~~~~~kI~lP~D~vv~~~~~~~~~~~~~~~~~~ip~~~~i~DIGp~Ti~~  302 (398)
T 1VPE_A          224 FLKAL-GKEVGSSRVEEDKIDLAKELVEKAKEKGVEIVLPVDAVIAQKIEPGVEKKVVRIDDGIPEGWMGLDIGPETIEL  302 (398)
T ss_dssp             HHHHT-SCCCTTSCCCGGGHHHHHHHHHHHHHTTCEEECCSEEEEESSCSTTCCCEEEETTTCCCTTCEEEEECHHHHHH
T ss_pred             HHHHh-CCCccCCcccHHHHHHHHHHHHHHHHcCCEEEceeeeEeccCCCCCCcceEEecccCCCCCcccCCCCHHHHHH
Confidence            99998 88999999999999999999999989999999999999998653322111111123788899999999999999


Q NP_000282.1     324 YAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELL  403 (417)
Q Consensus       324 ~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le~L  403 (417)
                      |.++|++|||||||||||+||+++|++||+++++++++++++++++|+|||||+++++++|+.++++||||||||+||||
T Consensus       303 ~~~~I~~aktI~wnGP~G~~E~e~f~~GT~~i~~ai~~~~~~~a~sivGGGdT~~~~~~~g~~~~~s~vStgGGA~Le~L  382 (398)
T 1VPE_A          303 FKQKLSDAKTVVWNGPMGVFEIDDFAEGTKQVALAIAALTEKGAITVVGGGDSAAAVNKFGLEDKFSHVSTGGGASLEFL  382 (398)
T ss_dssp             HHHHHTTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHHHHTTCEEEEESHHHHHHHHHTTCGGGSSEEESCHHHHHHHH
T ss_pred             HHHHHhcCCEEEEeCCCCcccCcccchhHHHHHHHHHHhhhCCcEEEEcchHHHHHHHHcCCCCcceEEEcchHHHHHHH
Confidence            99999999999999999999887899999999999976322478999999999998888888788999999999999999


Q NP_000282.1     404 EGKVLPGVDALSN  416 (417)
Q Consensus       404 ~G~~LPgl~aL~~  416 (417)
                      +|++||||++|++
T Consensus       383 ~G~~LPgl~aL~~  395 (398)
T 1VPE_A          383 EGKELPGIASMRI  395 (398)
T ss_dssp             TSSCCHHHHTSCB
T ss_pred             cCCCCCcHHHhhh
Confidence            9999999999975


No 10
>4FEY_A Phosphoglycerate kinase (E.C.2.7.2.3); Structural Genomics, NIAID, National Institute; HET: ADP; 2.3A {Francisella tularensis subsp. tularensis}
Probab=100.00  E-value=5.5e-110  Score=841.97  Aligned_cols=388  Identities=44%  Similarity=0.740  Sum_probs=352.5  Template_Neff=6.400

Q NP_000282.1       2 SLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPV   81 (417)
Q Consensus         2 ~~~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~v   81 (417)
                      .||++++++|.|++||+||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++.+||+||
T Consensus         2 ~~~~~~~l~~~~l~gK~vl~RvD~NVPl~~~~i~dd~RI~~~lpTI~~Ll~~ga-~vvl~sHlGrP~~~~~~~~~Sl~pv   80 (395)
T 4FEY_A            2 NAMSFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGG-AVILMSHLGRPTEGEYDSQFSLEPV   80 (395)
T ss_dssp             --CCSCBGGGSCCTTCEEEEECCCCCCEETTEESCCHHHHHTHHHHHHHHHHTC-EEEEECCCSCCCTTSCCGGGCSHHH
T ss_pred             CcccccccccccCCCCEEEEEeeCCCcccCCccCCcHHHHHHHHHHHHHHHCCC-EEEEEeecCCCCCCCCCcccCHHHH
Confidence            478899999999999999999999999988899999999999999999999999 5999999999987522458999999


Q NP_000282.1      82 AVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVY  161 (417)
Q Consensus        82 a~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Diy  161 (417)
                      +++|+++|+.+|.|+++|++.      .++++|+|+||||+|||++|+++               +.+|+++||+++|+|
T Consensus        81 a~~L~~~l~~~v~f~~d~~~~------~~~~~g~illLENlRf~~~E~~~---------------~~~fa~~La~l~Diy  139 (395)
T 4FEY_A           81 AKALSEIINKPVKFAKDWLDG------VDVKAGEIVMCENVRFNSGEKKS---------------TDDLSKKIASLGDVF  139 (395)
T ss_dssp             HHHHHHHHCSCEEEESSTTTC------CCCCTTCEEEECCGGGSTTTTTT---------------CHHHHHHHHHTCSEE
T ss_pred             HHHHHHHhCCceeecccccCC------CCCCCCeEEEEecccccCcccCC---------------chHHHHHHHhcchHh
Confidence            999999998779999999884      27889999999999999876421               367999999999999


Q NP_000282.1     162 VNDAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGG  239 (417)
Q Consensus       162 VNDAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~  239 (417)
                      |||||+++||.|||+++++  +|+++||++|++|+++|++++++|+||+++|+||+|++||+++|++|+++||.|++||+
T Consensus       140 VnDAF~~~HR~~aS~vgi~~~lp~s~aG~l~~kEl~~L~~~~~~p~~P~v~IlGGaKv~dKi~~i~~Ll~~~d~iligG~  219 (395)
T 4FEY_A          140 VMDAFATAHRAQASTYGVAKYIPVACAGILLTNEIQALEKALKSPKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGG  219 (395)
T ss_dssp             EECCGGGTTSCCCCCCCHHHHSSEEEECHHHHHHHHHHHHHHTSCCSSEEEEEEESCHHHHHHHHHHHTTTCSEEEEEEH
T ss_pred             hhhcHhHcchhccccccccccCCcchHhHHHHHHHHHHHHHHhCCCCCeEEEECCCcHHHHHHHHHHHHHhCCEEEeccH
Confidence            9999999999999999998  66689999999999999999999999999999999999999999999999999999999


Q NP_000282.1     240 MAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPE  319 (417)
Q Consensus       240 ~a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~  319 (417)
                      ||++||+|+ |+++|+|++|++..+.|++++++|+.++++|++|+|++|.+++..+.... ......+|++|+++||||+
T Consensus       220 ~a~tfl~a~-g~~vg~s~~e~~~~~~a~~il~~a~~~~~ki~lP~D~~v~~~~~~~~~~~-~~~~~~ip~~~~~~DIGp~  297 (395)
T 4FEY_A          220 IANTFIKAE-GFDVGNSLYEQDLVAEATEILAKAKALGVNIPVPVDVRVAKEFSENAQAI-IKKVSDVVADEMILDIGPE  297 (395)
T ss_dssp             HHHHHHHHT-TCCCTTCCCCGGGHHHHHHHHHHHHHTTCBCCCCSEEEEESSSSTTCCCE-EEEGGGCCTTCEEEEECHH
T ss_pred             HHHHHHHHc-CCccCCcccchhHHHHHHHHHHHHHHhCCceeeeeeEEecccccccccce-EeeHHHCCCCcEeccCCHH
Confidence            999999998 88999999999889999999999999999999999999998754322211 1112478899999999999


Q NP_000282.1     320 SSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGAS  399 (417)
Q Consensus       320 Ti~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~  399 (417)
                      |++.|.+.|++|||||||||||+||.++|++||+++++++++.   ++++|+|||||+++++++|+.++++||||||||+
T Consensus       298 Ti~~~~~~i~~aktI~wnGP~G~~E~~~f~~GT~~i~~aia~~---~a~~ivGGGdT~~~~~~~g~~~~~s~vStgGGA~  374 (395)
T 4FEY_A          298 SQKIIAELLKSANTILWNGPVGVFEFDNFAEGTKALSLAIAQS---HAFSVAGGGDTIAAIEKFGIKDQVSYISTAGGAF  374 (395)
T ss_dssp             HHHHHHHHHHHCSEEEEECCSSCTTSGGGCHHHHHHHHHHHHH---CSEEEEESHHHHHHHHHTTCSTTSSEEECCSHHH
T ss_pred             HHHHHHHHHHhCCEEEEcCCCCcccccccChHHHHHHHHHHhC---CCcEEEechHHHHHHHHcCCCcCcEEEEcchHHH
Confidence            9999999999999999999999998888999999999999762   6899999999998888889888999999999999


Q NP_000282.1     400 LELLEGKVLPGVDALSN  416 (417)
Q Consensus       400 Le~L~G~~LPgl~aL~~  416 (417)
                      ||||+|+.||||++|++
T Consensus       375 Le~L~G~~LPgleaL~~  391 (395)
T 4FEY_A          375 LEFLEGKKLPAIEILKE  391 (395)
T ss_dssp             HHHHTTCCCHHHHHHHH
T ss_pred             HHHHcCCCCchHHHHHH
Confidence            99999999999999975


No 11
>1V6S_B Phosphoglycerate kinase (E.C.2.7.2.3); phosphoglycerate kinase, Thermus thermophilus, RIKEN; HET: GOL; 1.5A {Thermus thermophilus} SCOP: c.86.1.1
Probab=100.00  E-value=1.2e-109  Score=838.81  Aligned_cols=386  Identities=44%  Similarity=0.774  Sum_probs=350.7  Template_Neff=6.500

Q NP_000282.1       7 LTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELK   86 (417)
Q Consensus         7 ~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~~L~   86 (417)
                      ++++|.|++|||||||+|+|||+++++|.|++||++++|||+||++ ++++|||+||+|||+++  ++.+||+||+++|+
T Consensus         2 ~~l~d~~l~gK~vl~R~D~NVPi~~~~i~d~~RI~~~lpTI~~Ll~-~~~~vvl~sHlGrP~~~--~~~~Sl~pva~~L~   78 (390)
T 1V6S_B            2 RTLLDLDPKGKRVLVRVDYNVPVQDGKVQDETRILESLPTLRHLLA-GGASLVLLSHLGRPKGP--DPKYSLAPVGEALR   78 (390)
T ss_dssp             CBGGGCCCTTCEEEEECCCCCCEETTEESCCHHHHHHHHHHHHHHH-TTCEEEEECCCSCCSSC--CGGGCSHHHHHHHH
T ss_pred             CCccccCCCCCEEEEEeeccccccCCccCCcHHHHhHHHHHHHHHh-CCCeEEEEeccCCCCCC--CcccchHHHHHHHH
Confidence            5677788999999999999999998899999999999999999999 54359999999999865  35799999999999


Q NP_000282.1      87 SLLGKDVLFLKDCVG-PEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDA  165 (417)
Q Consensus        87 ~~l~~~v~f~~~~~~-~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVNDA  165 (417)
                      ++|+. |.|++++++ +++.+.++.+++|+|+||||+|||++|+++               +.+|+++||+++|+|||||
T Consensus        79 ~~l~~-v~f~~~~~~~~~~~~~i~~~~~g~i~lLENlRf~~~E~~n---------------~~~fa~~La~l~DiyVNDA  142 (390)
T 1V6S_B           79 AHLPE-ARFAPFPPGSEEARREAEALRPGEVLLLENVRFEPGEEKN---------------DPELSARYARLGEAFVLDA  142 (390)
T ss_dssp             TTCTT-EEECCSCTTSHHHHHHHHTCCTTCEEECCCGGGSTTTTTT---------------CHHHHHHHGGGCSEEEECC
T ss_pred             HHCCC-cEeCCCCCCcHHHHHHHHHcCCCCEEEEeccCCCCCcccC---------------CHHHHHHHHhhcceEeeec
Confidence            99986 899998888 677778889999999999999999866422               3679999999999999999


Q NP_000282.1     166 FGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFT  243 (417)
Q Consensus       166 Fg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a~t  243 (417)
                      ||++||.|||+++++  +| ++||++|++|+++|++++++|+||+++|+||+|++||+++|++|++++|.|++||+|||+
T Consensus       143 F~~~HR~hAS~vgi~~~lp-s~aG~ll~kEl~~L~~~l~~p~~P~v~IlGGaKv~dKi~~i~~Ll~~~D~IligG~~a~t  221 (390)
T 1V6S_B          143 FGSAHRAHASVVGVARLLP-AYAGFLMEKEVRALSRLLKDPERPYAVVLGGAKVSDKIGVIESLLPRIDRLLIGGAMAFT  221 (390)
T ss_dssp             GGGTTSCCCCCCCGGGTSC-EEECHHHHHHHHHHHHTTSCCCSSEEEEECCSCGGGTHHHHHHHGGGCSEEEECSTHHHH
T ss_pred             hhhcCcccchhhHHHhhHH-hhccHHHHHHHHHHHHHHcCCCCCEEEEEcCCCHHHHHHHHHHHHHHCCEEEEcchHHHH
Confidence            999999999999999  67 899999999999999999999999999999999999999999999988999999999999


Q NP_000282.1     244 FLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKK  323 (417)
Q Consensus       244 fl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti~~  323 (417)
                      ||+|+ |+++|+|++|++..+.|++++++|+.++++|++|+|++|.+.+...... ...+...+|++|+++||||+|++.
T Consensus       222 fL~a~-g~~ig~s~~e~~~~~~a~~il~~a~~~~~ki~lP~D~vv~~~~~~~~~~-~~~~~~~ip~~~~~~DIGp~Ti~~  299 (390)
T 1V6S_B          222 FLKAL-GGEVGRSLVEEDRLDLAKDLLGRAEALGVRVYLPEDVVAAERIEAGVET-RVFPARAIPVPYMGLDIGPKTREA  299 (390)
T ss_dssp             HHHHT-TCBCTTCCCCGGGHHHHHHHHHHHHHTTCEEECCSEEEEESSCCTTCCC-EEEETTBCCTTCEEEEECHHHHHH
T ss_pred             HHHHc-CCCccccccchhHHHHHHHHHHHHHHhCCeEEceeceeeccccccCCce-EEecCccCCCCcccccCCHHHHHH
Confidence            99998 8899999999999999999999888899999999999998865322111 112224788899999999999999


Q NP_000282.1     324 YAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELL  403 (417)
Q Consensus       324 ~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le~L  403 (417)
                      |+++|++|||||||||||+||+++|++||+++++++++++  ++++|+|||||+++++++|+.++++||||||||+||||
T Consensus       300 ~~~~i~~aktI~wnGp~G~~E~~~f~~GT~~i~~~i~~~~--~a~~iiGGGdT~~~~~~~g~~~~~~~vStgGGA~L~~L  377 (390)
T 1V6S_B          300 FARALEGARTVFWNGPMGVFEVPPFDEGTLAVGQAIAALE--GAFTVVGGGDSVAAVNRLGLKERFGHVSTGGGASLEFL  377 (390)
T ss_dssp             HHHHHTTCSEEEEESCSSCTTSTTTTHHHHHHHHHHHHCS--SCEEEEESHHHHHHHHHTTCGGGSSEECCSSSCHHHHH
T ss_pred             HHHHHhcCCEEEEeCCCcccCCCCcchHHHHHHHHHHHcc--CCEEEEeCHHHHHHHHHcCCCCcceEEecchHHHHHHH
Confidence            9999999999999999999988889999999999997632  78999999999999999898889999999999999999


Q NP_000282.1     404 EGKVLPGVDALSN  416 (417)
Q Consensus       404 ~G~~LPgl~aL~~  416 (417)
                      +|+.||||++|++
T Consensus       378 ~g~~LPgl~aL~~  390 (390)
T 1V6S_B          378 EKGTLPGLEVLEG  390 (390)
T ss_dssp             HHSCCHHHHTTCC
T ss_pred             hcCCCCcchhccC
Confidence            9999999999974


No 12
>3ZLB_A PHOSPHOGLYCERATE KINASE (E.C.2.7.2.3); TRANSFERASE; HET: ANP, GOL; 1.78A {STREPTOCOCCUS PNEUMONIAE}
Probab=100.00  E-value=1.6e-109  Score=839.96  Aligned_cols=394  Identities=46%  Similarity=0.789  Sum_probs=353.2  Template_Neff=6.500

Q NP_000282.1       4 SNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAV   83 (417)
Q Consensus         4 ~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~   83 (417)
                      |++++++|.|++|||||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++.+||+||++
T Consensus         1 ~~~~~l~~~~l~gK~vlvR~D~NVPi~~~~i~dd~RI~~~lpTI~~Ll~~ga-kvil~sHlGRP~g~~~~~~~Sl~pva~   79 (398)
T 3ZLB_A            1 MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGG-RAILFSHLGRVKEESDKAGKSLAPVAA   79 (398)
T ss_dssp             CCBCBGGGSCCTTCEEEEECCCCCCEETTEESCCHHHHHHHHHHHHHHHTTC-EEEEECCCSCCCSGGGSTTCCSHHHHH
T ss_pred             CCccccccccCCCCEEEEEeeCCCccCCCCcCCChHHHHHHHHHHHHHHCCC-eEEEEeecCccCCcccccCcchHHHHH
Confidence            4677888888999999999999999998899999999999999999999999 599999999998753134799999999


Q NP_000282.1      84 ELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGD-VYV  162 (417)
Q Consensus        84 ~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~D-iyV  162 (417)
                      +|+++|+.+|.|+++|+|+++++.++.+++|+|+||||+|||++|... +.          .++.+|+++||+++| +||
T Consensus        80 ~L~~~l~~~v~f~~~~~g~~~~~~i~~~~~g~i~lLENlRf~~~E~~~-e~----------~n~~~fa~~La~l~d~iyV  148 (398)
T 3ZLB_A           80 DLAAKLGQDVVFPGVTRGAELEAAINALEDGQVLLVENTRYEDVDGKK-ES----------KNDPELGKYWASLGDGIFV  148 (398)
T ss_dssp             HHHHHHTSCEECCSCSSSHHHHHHHHTCCTTCEEECCCGGGGGTTTCT-TT----------TTCHHHHHHHHHTSSSEEE
T ss_pred             HHHHHhCCceeCCCCCCCHHHHHHHHhccCCCEEEEecccccCCCCCc-cc----------cccHHHHHHHHhcCCcEEE
Confidence            999999877999999999888888899999999999999999865211 10          114789999999988 999


Q NP_000282.1     163 NDAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM  240 (417)
Q Consensus       163 NDAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~  240 (417)
                      ||||+++||.|||+++++  +|+++||++|++||++|++++++|+||+++|+||+|++||+++|++|++++|.|++||+|
T Consensus       149 NDAF~~~HR~hAS~vgi~~~lp~s~aG~ll~kEl~~L~~~l~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~iligG~~  228 (398)
T 3ZLB_A          149 NDAFGTAHRAHASNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGM  228 (398)
T ss_dssp             ECCGGGTTSCCCCCCCHHTTSSEEEECHHHHHHHCCCCCHHHSCCSSEEEEECSSCSTTTHHHHHHHHHHCSEEEECTTH
T ss_pred             ecchhhcccccchhhhhhHhhchHhHHHHHHHHHHHHHHHHHCCCCCEEEEEcCCCHHHHHHHHHHHHHHhCceEeCchH
Confidence            999999999999999999  666899999999999999999999999999999999999999999999988999999999


Q NP_000282.1     241 AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPES  320 (417)
Q Consensus       241 a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~T  320 (417)
                      ||+||+|+ |+++|+|++|++..+.|++++++   ++++|++|+|++|.+.+...... ...+...+|++|+++||||+|
T Consensus       229 a~tfL~a~-g~~ig~S~~e~~~~~~a~~ll~~---~~~ki~lP~D~vv~~~~~~~~~~-~~~~~~~i~~~~~~~DIGp~T  303 (398)
T 3ZLB_A          229 TYTFYKAQ-GIEIGNSLVEEDKLDVAKALLEK---ANGKLILPVDSKEANAFAGYTEV-RDTEGEAVSEGFLGLDIGPKS  303 (398)
T ss_dssp             HHHHHHHT-TCCCTTCCCCGGGHHHHHHHHHH---STTCEECCSCEEEESSSSSCSCE-EECSSSCCCTTCEEEEECHHH
T ss_pred             HHHHHHHc-CCcccCcccccchHHHHHHHHHH---cCCceEeeccchhhhcccCCCce-eeeccccccCCCeeecCCHHH
Confidence            99999998 88999999999888999999875   47899999999998864332111 111124788899999999999


Q NP_000282.1     321 SKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASL  400 (417)
Q Consensus       321 i~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~L  400 (417)
                      ++.|.+.|++|||||||||||+||.++|++||+++++++++++  ++++|+|||||+++++++|+.++|+||||||||+|
T Consensus       304 i~~~~~~I~~aktI~wnGP~G~~E~~~f~~GT~~i~~~i~~~~--~a~~iiGGGdT~~~~~~~g~~~~~s~vStgGGA~L  381 (398)
T 3ZLB_A          304 IAKFDEALTGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQP--GVKSIIGGGDSAAAAINLGRADKFSWISTGGGASM  381 (398)
T ss_dssp             HHHHHHHHTTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHTST--TCEEEECCHHHHHHHHHTTCGGGSSEECCCTHHHH
T ss_pred             HHHHHHHHhcCCEEEEeCCCCccCCccccchHHHHHHHHHcCC--CCcEEEecccHHHHHHHcCCCCCCeEEEcchHHHH
Confidence            9999999999999999999999998889999999999997632  78999999999988888888778999999999999


Q NP_000282.1     401 ELLEGKVLPGVDALSN  416 (417)
Q Consensus       401 e~L~G~~LPgl~aL~~  416 (417)
                      |||+|+.||||++|++
T Consensus       382 e~L~G~~LPgl~aL~~  397 (398)
T 3ZLB_A          382 ELLEGKVLPGLAALTE  397 (398)
T ss_dssp             HHHTTCCCHHHHTSCB
T ss_pred             HHHcCCCCchHHHhhc
Confidence            9999999999999975


No 13
>4EHJ_A Phosphoglycerate kinase (E.C.2.7.2.3); Structural Genomics, Center for Structural; HET: MSE; 2.71A {Francisella tularensis subsp. tularensis}
Probab=100.00  E-value=2e-109  Score=837.07  Aligned_cols=386  Identities=44%  Similarity=0.744  Sum_probs=350.7  Template_Neff=6.400

Q NP_000282.1       4 SNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAV   83 (417)
Q Consensus         4 ~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~   83 (417)
                      |++++++|.|++||+||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++.+||+||++
T Consensus         1 ~~~~~l~~~~l~gK~vl~R~D~NVpl~~~~i~dd~RI~~~lpTI~~Ll~~ga-~vvl~sHlGrP~~~~~~~~~Sl~pva~   79 (392)
T 4EHJ_A            1 MSFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGG-AVILMSHLGRPTEGEYDSQFSLEPVAK   79 (392)
T ss_dssp             -CCCBGGGSCCTTCEEEEECCCCCCEETTEESCCHHHHHHHHHHHHHHHTTC-EEEEECCCSCCCTTCCCGGGCSHHHHH
T ss_pred             CCccccccccCCCCEEEEEeeCCCcccCCccCCcHHHHHHHHHHHHHHHCCC-eEEEEeecCCCCCCCCCcccCHHHHHH
Confidence            4578888888999999999999999988899999999999999999999999 699999999998752245899999999


Q NP_000282.1      84 ELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVN  163 (417)
Q Consensus        84 ~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVN  163 (417)
                      +|+++|+.+|.|+++|++.      .++++|+|+||||+|||++|+++               +.+|+++||+++|+|||
T Consensus        80 ~L~~~l~~~v~f~~d~~~~------~~~~~g~illLENlRf~~~E~~~---------------~~~fa~~La~~~DiyVn  138 (392)
T 4EHJ_A           80 ALSEIINKPVKFAKDWLDG------VDVKAGEIVMCENVRFNSGEKKS---------------TDDLSKKIASLGDVFVM  138 (392)
T ss_dssp             HHHHHHTSCEEEETTCTTC------CCCCTTCEEEECCGGGSTTTTTT---------------CHHHHHHHHHTCSEEEE
T ss_pred             HHHHHhCCceeecccccCC------CCCCCCeEEEEecccccCcccCC---------------chHHHHHHHhcchHhhh
Confidence            9999998779999999885      27889999999999999876421               36799999999999999


Q NP_000282.1     164 DAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMA  241 (417)
Q Consensus       164 DAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a  241 (417)
                      |||+++||.|||+++++  +|+++||++|++|+++|++++++|+||+++|+||+|++||+++|++|+++||.|++||+||
T Consensus       139 DAF~~~HR~~aS~vgi~~~lp~s~aG~l~~kEl~~L~~~~~~p~~P~v~IiGGaKv~dKi~~i~~Ll~~~D~IligG~~a  218 (392)
T 4EHJ_A          139 DAFATAHRAQASTYGVAKYIPVACAGILLTNEIQALEKALKSPKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGGIA  218 (392)
T ss_dssp             CCGGGTTSCCCCCCCHHHHSSEEEECHHHHHHHHHHHHHHTSCCSSEEEEEECSCHHHHHHHHHHHTTTCSEEEEETHHH
T ss_pred             hcHhHccccccccccccccCCcchHhHHHHHHHHHHHHHHhCCCCCEEEEECCCcHHHHHHHHHHHHHhCCEEEeccHHH
Confidence            99999999999999999  6668999999999999999999999999999999999999999999999999999999999


Q NP_000282.1     242 FTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESS  321 (417)
Q Consensus       242 ~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  321 (417)
                      ++||+|+ |+++|+|++|++..+.|++++++|+.++++|++|+|++|.+++..+.... ......+|++|+++||||+|+
T Consensus       219 ~tfl~a~-g~~vg~s~~e~~~~~~a~~il~~a~~~~~kI~lP~D~~v~~~~~~~~~~~-~~~~~~i~~~~~~~DIGp~T~  296 (392)
T 4EHJ_A          219 NTFIKAE-GFDVGNSLYEQDLVAEATEILAKAKALGVNIPVPVDVRVAKEFSENAQAI-IKKVSDVVADEMILDIGPESQ  296 (392)
T ss_dssp             HHHHHHT-TCCCTTCSCCGGGHHHHHHHHHHHHHHTCBCCCCSEEEEESSCSTTCCCE-EEEGGGCCTTCEEEEECHHHH
T ss_pred             HHHHHHc-CCccCCcccchhHHHHHHHHHHHHHHhCCceeeeeeEEecccccccccce-EeeHHHCCCCcEeccCCHHHH
Confidence            9999998 88999999999888999999999988999999999999998754322211 111247888999999999999


Q NP_000282.1     322 KKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLE  401 (417)
Q Consensus       322 ~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le  401 (417)
                      +.|++.|++|||||||||||+||.++|++||+++++++++.   ++++|+|||||+++++++|+.++++||||||||+||
T Consensus       297 ~~~~~~i~~aktI~wnGp~G~~E~~~f~~GT~~i~~ai~~~---~a~~vvGGGdT~~~~~~~g~~~~~~~vStgGGA~Le  373 (392)
T 4EHJ_A          297 KIIAELLKSANTILWNGPVGVFEFDNFAEGTKALSLAIAQS---HAFSVAGGGDTIAAIEKFGIKDQVSYISTAGGAFLE  373 (392)
T ss_dssp             HHHHHHHHHCSEEEEECCSSCTTSGGGCHHHHHHHHHHHHC---CSEEEECSHHHHHHHHHHTCGGGSSEECCCSHHHHH
T ss_pred             HHHHHHHHhCCEEEEcCCCCcccccccChHHHHHHHHHHhC---CCcEEEechHHHHHHHHcCCCcCcEEEEcchHHHHH
Confidence            99999999999999999999998888999999999999762   689999999999888888988899999999999999


Q NP_000282.1     402 LLEGKVLPGVDALSN  416 (417)
Q Consensus       402 ~L~G~~LPgl~aL~~  416 (417)
                      ||+|+.||||++|++
T Consensus       374 ~L~G~~LPgl~aL~~  388 (392)
T 4EHJ_A          374 FLEGKKLPAIEILKE  388 (392)
T ss_dssp             HHTTCCCHHHHHHHH
T ss_pred             HHcCCCCchHHHHHH
Confidence            999999999999975


No 14
>16PK_A 3-PHOSPHOGLYCERATE KINASE, 1,1,5,5-TETRAFLUOROPHOSPHOPENTYLPHOSPHONIC ACID ADENYLATE; KINASE, PHOSPHOGLYCERATE, TERNARY COMPLEX, GLYCOLYSIS; HET: EPE, BIS; 1.6A {Trypanosoma brucei} SCOP: c.86.1.1
Probab=100.00  E-value=4.2e-109  Score=840.30  Aligned_cols=395  Identities=47%  Similarity=0.803  Sum_probs=351.6  Template_Neff=6.400

Q NP_000282.1       6 KLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPM-------------   72 (417)
Q Consensus         6 ~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~-------------   72 (417)
                      ++++++.|++|||||||+|+|||+++++|.|++||++++|||+||++ +|++|||+||+|||+++..             
T Consensus         2 ~~~l~~~~l~gK~vlvR~D~NVPl~~~~i~dd~RI~~~lpTI~~Ll~-~~~kvil~sHlGRP~g~~~~~~~~~~~~~~~~   80 (415)
T 16PK_A            2 KKSINECDLKGKKVLIRVDFNVPVKNGKITNDYRIRSALPTLKKVLT-EGGSCVLMSHLGRPKGIPMAQAGKIRSTGGVP   80 (415)
T ss_dssp             BCBGGGSCCTTCEEEEEECCCCCEETTEESCCHHHHHHHHHHHHHHH-TTCEEEEECCCSCCCCBCGGGHHHHHHTTCCT
T ss_pred             CCccchhhcCCCEEEEEeeCCCcccCCccCCcHHHHHHHHHHHHHHH-cCCeEEEEeecCCCCCCChhhccccccCCCCC
Confidence            56777788999999999999999987899999999999999999999 5545999999999986320             


Q NP_000282.1      73 --PDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAF  150 (417)
Q Consensus        73 --~~~~Sl~~va~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~f  150 (417)
                        .+.+||+||+++|+++|+.+|.|+++|+|  +.+.++.+++|+|+||||+|||++|++++ +          +++.+|
T Consensus        81 ~~~~~~Sl~pva~~L~~~l~~~V~f~~~~~~--~~~~i~~~~~g~i~lLENlRF~~~E~~~~-~----------~~~~~f  147 (415)
T 16PK_A           81 GFQQKATLKPVAKRLSELLLRPVTFAPDCLN--AADVVSKMSPGDVVLLENVRFYKEEGSKK-A----------KDREAM  147 (415)
T ss_dssp             TCCGGGCSHHHHHHHHHHHTSCCEEESCTTS--CHHHHHTCCTTCEEEECCGGGBGGGGCSS-H----------HHHHHH
T ss_pred             CcchhccHHHHHHHHHHHhCCcceeCCCcCC--HHHHHHhCCCCCEEEEecccccccccccc-c----------ccHHHH
Confidence              12689999999999999867999999998  45567799999999999999998765221 0          113789


Q NP_000282.1     151 RASLSKLGDVYVNDAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNML  228 (417)
Q Consensus       151 a~~LA~l~DiyVNDAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll  228 (417)
                      +++||+++|+|||||||++||.|||+++++  +|+++||++|++||++|.+++++|+||+++|+||+|++||+++|++|+
T Consensus       148 a~~La~l~DiyVNDAF~~~HR~hAS~vgi~~~lp~s~aG~ll~kEl~~L~~~~~~p~rP~v~IlGGaKv~dKi~~i~~Ll  227 (415)
T 16PK_A          148 AKILASYGDVYISDAFGTAHRDSATMTGIPKILGNGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNML  227 (415)
T ss_dssp             HHHHHTTCSEEEEECGGGTTSCCCCCCCHHHHHTCCEECHHHHHHHHHHHHHHSCCCSSEEEEECSSCSGGGHHHHHHHG
T ss_pred             HHHHHhccCeEEeechhhcccCcchhccHhHhhcccchHHHHHHHHHHHHHHHcCCCCCeEEEEcCCCHHHHHHHHHHHH
Confidence            999999999999999999999999999999  665899999999999999999999999999999999999999999999


Q NP_000282.1     229 DKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIP  308 (417)
Q Consensus       229 ~~~D~iligG~~a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~  308 (417)
                      +++|.|+|||+|||+||+|+ |+++|+|++|++..+.|++++++|+.++++|++|+|++|.+++...... ...+.+.+|
T Consensus       228 ~~~D~IligG~~a~tfl~a~-g~~vG~s~~e~~~~~~a~~ll~~a~~~~~kI~lP~D~~v~~~~~~~~~~-~~~~~~~i~  305 (415)
T 16PK_A          228 QRIDYLLIGGAMAYTFLKAQ-GYSIGKSKCEESKLEFARSLLKKAEDRKVQVILPIDHVCHTEFKAVDSP-LITEDQNIP  305 (415)
T ss_dssp             GGCSEEEECTTHHHHHHHHH-TCCCTTCCCCGGGHHHHHHHHHHHHHTTCEEECCSSEEEESSSSCCSSC-EECSSSCCC
T ss_pred             HHcCEEEeCchHHHHHHHHc-CCcccccccchhHHHHHHHHHHHHHhcCCEEEceeceeeccccCCCCCC-ceeccccCC
Confidence            98899999999999999998 8999999999999999999999888899999999999999875321111 111224788


Q NP_000282.1     309 AGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKAT-SRGCITIIGGGDTATCCAKWNTED  387 (417)
Q Consensus       309 ~~~~~~DIGp~Ti~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~-~~~~~~ivGGGdT~~~~~~~g~~~  387 (417)
                      ++|+++||||+|++.|++.|++|||||||||||+||+++|++||+++++++++++ .+++++|+|||||+++++++|+.+
T Consensus       306 ~~~~~~DIGp~Ti~~~~~~i~~aktI~wnGp~G~~E~~~f~~GT~~i~~~l~~~~~~~~a~~vvGGGdT~~~~~~~~~~~  385 (415)
T 16PK_A          306 EGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIAKAMGRGTHEHGLMSIIGGGDSASAAELSGEAK  385 (415)
T ss_dssp             TTCEEEEECHHHHHHHHHHHTTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHHHHHHCCEEEECSHHHHHHHHHTTCTT
T ss_pred             CCCcccccCHHHHHHHHHHHHcCCEEEEeCCCccccCCccccchHHHHHHHHhhcccCCceEEEcchhHHHHHHHhCCcc
Confidence            8999999999999999999999999999999999998889999999999997632 247899999999998888888888


Q NP_000282.1     388 KVSHVSTGGGASLELLEGKVLPGVDALSN  416 (417)
Q Consensus       388 ~~~~vStgGgA~Le~L~G~~LPgl~aL~~  416 (417)
                      +++||||||||+||||+|++||||++|++
T Consensus       386 ~~s~vStgGGA~Le~L~Gk~LPgl~aL~~  414 (415)
T 16PK_A          386 RMSHVSTGGGASLELLEGKTLPGVTVLDD  414 (415)
T ss_dssp             TSSEECSCHHHHHHHHTTCCCHHHHTSCB
T ss_pred             cCeEEEcchHHHHHHHcCCCCCchHhccc
Confidence            89999999999999999999999999975


No 15
>3OZ7_B Phosphoglycerate kinase (E.C.2.7.2.3); Phosphoglycerate kinase, Transferase, ATP Binding; HET: SO4; 2.7A {Plasmodium falciparum}
Probab=100.00  E-value=4.5e-109  Score=840.55  Aligned_cols=413  Identities=61%  Similarity=0.995  Sum_probs=361.2  Template_Neff=6.400

Q NP_000282.1       3 LSNKLTLDKL-DVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPV   81 (417)
Q Consensus         3 ~~~~~~i~~~-~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~v   81 (417)
                      ...++++.+. |++||+||||+|+|||+++++|.|++||++++|||+||+++||++|||+||+|||+++. ++.+||+||
T Consensus         4 ~~~~~~~~~~~~l~gk~vlvR~D~NVPi~~~~i~d~~Ri~~~lpTI~~Ll~~gak~vvl~sHlGRP~g~~-~~~~Sl~~v   82 (417)
T 3OZ7_B            4 LGNKLSISDLKDIKNKKVLVRVDFNVPIENGIIKDTNRITATLPTINHLKKEGASKIILISHCGRPDGLR-NEKYTLKPV   82 (417)
T ss_dssp             TTSCCBGGGCCCCTTCEEEEEECCCCCEETTEESCCHHHHTTHHHHHHHHHTTCSEEEEECCCSCCTTSC-CGGGCCSHH
T ss_pred             CCCCCChhhhhhcCCCEEEEEEeCCCcccCCccCCChhHHhHHHHHHHHHHcCCCEEEEEeeCCCCCCCC-CcccchHHH
Confidence            3567888876 89999999999999999888999999999999999999999994499999999998764 568999999


Q NP_000282.1      82 AVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVY  161 (417)
Q Consensus        82 a~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Diy  161 (417)
                      +++|+++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|++++++++.+..+.+.+++.+|++.||+++|+|
T Consensus        83 a~~L~~~l~~~v~f~~~~~g~~~~~~i~~~~~g~illLENlRf~~~E~~~~~~a~~~~~~~~~~~~~~fa~~La~~~diy  162 (417)
T 3OZ7_B           83 AETLKGLLGEEVLFLNDCVGKEVEDKINAAKENSVILLENLRFHIEEEGKGVDANGNKVKANKEDVEKFQNDLTKLADVF  162 (417)
T ss_dssp             HHHHHHHHTSCCEEESCSSSHHHHHHHHHSCTTEEEEECCGGGSHHHHSEEECTTSCEEECCHHHHHHHHHHHHTTCSEE
T ss_pred             HHHHHHHhCCEEEEecccCCHHHHHHHHHccCCCEEEEecccccchhccCCCCCCCCccccCHHhHHHHHHHHhhcCCEE
Confidence            99999999877999999999888888899999999999999999977632111000000111112467999999999999


Q NP_000282.1     162 VNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMA  241 (417)
Q Consensus       162 VNDAFg~aHR~~aS~~gi~l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a  241 (417)
                      |||||+++||.|||+++++...++||++|++||++|.+++++|+||+++|+||+|++||+++|++|+++||.|+|||+||
T Consensus       163 VnDAF~~~HR~~ASv~gi~~~~~~aG~l~~kEi~~L~~~~~~p~rP~v~IlGG~Kv~dKi~~i~~Ll~~~D~IligG~~a  242 (417)
T 3OZ7_B          163 INDAFGTAHRAHSSMVGVKLNVKASGFLMKKELEYFSKALENPQRPLLAILGGAKVSDKIQLIKNLLDKVDRMIIGGGMA  242 (417)
T ss_dssp             EEECGGGTTSCCHHHHCCCCSEEEECHHHHHHHHHHHHHHSSCCSSEEEEECSSCSGGGHHHHHHHHHHCSEEEECTTHH
T ss_pred             EecccccCCCCCCchHHHHhcHHhhCHHHHHHHHHHHHHHhCCCCCEEEEEcCCCHHHHHHHHHHHHHhCCEEEECcHHH
Confidence            99999999999999999993228999999999999999999999999999999999999999999999999999999999


Q NP_000282.1     242 FTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESS  321 (417)
Q Consensus       242 ~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  321 (417)
                      |+||+|++++++|+|++|++..+.|++++++|+.++++|++|+|++|.+....++....+...+.+|++|+++||||+|+
T Consensus       243 ~~fl~a~~~~~vg~s~~e~~~~~~a~~il~~a~~~~~ki~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  322 (417)
T 3OZ7_B          243 YTFKKVLNNMKIGTSLFDEAGSKIVGEIMEKAKAKNVQIFLPVDFKIADNFDNNANTKFVTDEEGIPDNWMGLDAGPKSI  322 (417)
T ss_dssp             HHHHHHHHCCCBTTCCCCTTTHHHHHHHHHHHHHTTCEEECCSEEEEESSSSTTSCEEEEETTTCBCTTCEEEEECHHHH
T ss_pred             HHHHHHHCCCcCCccccchhhHHHHHHHHHHHHHcCCEEEEeeeeeecccCCCCCcCceecCcCCCCCCcccccCCHHHH
Confidence            99999984558999999998999999999998889999999999999987533221111222237888999999999999


Q NP_000282.1     322 KKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLE  401 (417)
Q Consensus       322 ~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le  401 (417)
                      +.|+++|++|||||||||||+||.++|++||+++++++++++++++++|+|||||+++++++|+.++++||||||||+||
T Consensus       323 ~~~~~~I~~aktI~wnGplG~~E~~~f~~GT~~i~~~l~~~~~~~a~~vvGGGdT~~~~~~~g~~~~~~~vSTgGGA~Le  402 (417)
T 3OZ7_B          323 ENYKDVILTSKTVIWNGPQGVFEMPNFAKGSIECLNLVVEVTKKGAITIVGGGDTASLVEQQNKKNEISHVSTGGGASLE  402 (417)
T ss_dssp             HHHHHHHHTCSEEEEESCSBCTTSGGGCHHHHHHHHHHHHHHHHTCEEEECSHHHHHHHHHHTCGGGSSEECCCSHHHHH
T ss_pred             HHHHHHHHhCCEEEEeCCCccccCCCcChhHHHHHHHHHHHhcCCCEEEEeChHHHHHHHHcCCCCCcEEEEechHHHHH
Confidence            99999999999999999999999888999999999999763224789999999999988888887789999999999999


Q NP_000282.1     402 LLEGKVLPGVDALSN  416 (417)
Q Consensus       402 ~L~G~~LPgl~aL~~  416 (417)
                      ||+|++||||++|++
T Consensus       403 ~L~G~~LPgi~aL~~  417 (417)
T 3OZ7_B          403 LLEGKELPGVLALSN  417 (417)
T ss_dssp             HHTTCCCHHHHTSCC
T ss_pred             HHcCCCCChhHhhcC
Confidence            999999999999974


No 16
>4DG5_A Phosphoglycerate kinase (E.C.2.7.2.3); Bi-lobal protein, Transferase, ATP Synthesis; 2.3A {Staphylococcus aureus}
Probab=100.00  E-value=5.2e-109  Score=836.15  Aligned_cols=392  Identities=44%  Similarity=0.770  Sum_probs=353.4  Template_Neff=6.300

Q NP_000282.1       5 NKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVE   84 (417)
Q Consensus         5 ~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~~   84 (417)
                      .++++.+.|++|||||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++.+||+||+++
T Consensus         9 ~~~~~~~~dl~gK~vlvR~D~NVP~~~~~i~dd~RI~~~lpTI~~L~~~ga-kvvl~sHlGrP~g~~~~~~~Sl~pva~~   87 (403)
T 4DG5_A            9 AKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGG-KIVLFSHLGKVKEESDKAKLTLRPVAED   87 (403)
T ss_dssp             CBCBGGGSCCTTCEEEEECCCCCCCSSSCCSCTHHHHHHHHHHHHHHHTTC-EEEEECCCSCCCSGGGSGGGCSHHHHHH
T ss_pred             ccccCCchhcCCCEEEEEeecccccCCCCcCCchHHHHHHHHHHHHHHCCC-EEEEEeccCccCCccchhhcchHHHHHH
Confidence            467788889999999999999999998899999999999999999999999 5999999999987522457999999999


Q NP_000282.1      85 LKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVND  164 (417)
Q Consensus        85 L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVND  164 (417)
                      |+++|+.+|.|+++|+|+++++.++.+++|+|+||||+|||++|.+. +.          +++.+|++.||+++|+||||
T Consensus        88 L~~~l~~~V~f~~d~~g~~~~~~i~~~~~g~illLENlRf~~~E~~~-e~----------~n~~~fa~~LA~l~DiyVND  156 (403)
T 4DG5_A           88 LSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKK-ES----------KNDPELGKYWASLGDVFVND  156 (403)
T ss_dssp             HHHHHTSCCEEESCSSSHHHHHHHHTCCTTCEEEECCGGGGGTTTTT-TT----------TTCHHHHHHHHTTCSEEEEC
T ss_pred             HHHHcCCeEEecCCcCCHHHHHHHHhccCCCEEEEccccccCCCCCc-cc----------ccCHHHHHHHHhcchHhhhc
Confidence            99999877999999999888888899999999999999999865211 10          11478999999999999999


Q NP_000282.1     165 AFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAF  242 (417)
Q Consensus       165 AFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a~  242 (417)
                      |||++||.|||+++++  +| ++||++|++|+++|.+++++|+||+++|+||+|++||+++|++|++++|.|++||+|||
T Consensus       157 AF~~~HR~hAS~vgi~~~lp-s~aG~ll~kEl~~L~k~~~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~IligG~lA~  235 (403)
T 4DG5_A          157 AFGTAHREHASNVGISTHLE-TAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAY  235 (403)
T ss_dssp             CGGGTTSCCCCCCCHHTSSC-EEECHHHHHHCCCCCHHHHSCCSSEEEEECSSCHHHHHHHHHHHTTTCSEEEECSTTHH
T ss_pred             CHhHccCcCcchHHHHHHHH-HHhhHHHHHHHHHHHHHHhCCCCCEEEEEcCCcHHHHHHHHHHHHHHcCEEEEcchHHH
Confidence            9999999999999999  67 89999999999999999999999999999999999999999999998899999999999


Q NP_000282.1     243 TFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSK  322 (417)
Q Consensus       243 tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti~  322 (417)
                      +||+|+ |+++|+|++|++..+.|++++++   ++++|++|+|++|.+.+..++... ..+.+.+|++|+++||||+|++
T Consensus       236 tfL~a~-g~~vg~s~~e~~~~~~a~~ll~~---~~~ki~lP~D~~v~~~~~~~~~~~-~~~~~~i~~~~~~~DIGp~Ti~  310 (403)
T 4DG5_A          236 TFLKAQ-GKEIGISLLEEDKIDFAKDLLEK---HGDKIVLPVDTKVAKEFSNDAKIT-VVPSDSIPADQEGMDIGPNTVK  310 (403)
T ss_dssp             HHHHHT-TCCCTTSCCCGGGHHHHHHHHHH---STTTEECCSEEEEESSSSTTSCCE-EEEGGGCCTTCEEEEECHHHHH
T ss_pred             HHHHHc-CCeeeeeecchhhHHHHHHHHHH---ccCceEeeceeeeecccCCCCceE-EecCCCCCCCcccccCCHHHHH
Confidence            999998 88999999999888999998873   588999999999998754322211 1122578889999999999999


Q NP_000282.1     323 KYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLEL  402 (417)
Q Consensus       323 ~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le~  402 (417)
                      .|.+.|++|||||||||||+||.++|++||+++++++++++  ++++|+|||||+++++++|+.++++||||||||+|||
T Consensus       311 ~~~~~I~~aktI~wnGP~G~~E~e~f~~GT~~i~~aia~~~--~a~~ivGGGdT~~~~~~~g~~~~~~~vStGGGA~Le~  388 (403)
T 4DG5_A          311 LFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLK--DAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEY  388 (403)
T ss_dssp             HHHHTTTTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHCS--SSEEEECSHHHHHHHHHTTCGGGSSEECSCHHHHHHH
T ss_pred             HHHHHHhcCCEEEEeCCCccccCccccchHHHHHHHHHhcC--CCEEEEeCchHHHHHHHcCCCCCceEEEechHHHHHH
Confidence            99999999999999999999988889999999999997632  7899999999999998889888899999999999999


Q NP_000282.1     403 LEGKVLPGVDALSN  416 (417)
Q Consensus       403 L~G~~LPgl~aL~~  416 (417)
                      |+|+.||||++|++
T Consensus       389 L~Gk~LPgl~aL~~  402 (403)
T 4DG5_A          389 LEGKELPGIKAINN  402 (403)
T ss_dssp             HTTCCCHHHHTSCB
T ss_pred             HcCCCCCchHHhhc
Confidence            99999999999975


No 17
>6HXE_A Phosphoglycerate kinase (E.C.2.7.2.3); Complex, 3-phosphoglycerate, hinge binding, TRANSFERASE; HET: 3PG; 2.1A {Pseudomonas sp. 'TAC II 18'}
Probab=100.00  E-value=4.3e-108  Score=826.14  Aligned_cols=381  Identities=39%  Similarity=0.690  Sum_probs=341.5  Template_Neff=6.400

Q NP_000282.1       4 SNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAV   83 (417)
Q Consensus         4 ~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~   83 (417)
                      |.++++++.|++||+||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++++||+||++
T Consensus         1 ~~~~~l~~~~l~gK~vl~R~D~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~ga-~vil~sHlGrP~g~~~~~~~Sl~~va~   79 (387)
T 6HXE_A            1 MTVLKMTDLDLQGKRVLIREDLNVPVKDGVVTSDARILASLPTIKLALEKGA-AVMVCSHLGRPTEGEFSAENSLKPVAD   79 (387)
T ss_dssp             -CCCBGGGSCCTTCEEEEECCCCCCEETTEECCCHHHHHHHHHHHHHHHTTC-EEEEECCCSCCCTTSCCGGGCSHHHHH
T ss_pred             CCccccchhhcCCCEEEEEeecCccccCCccCCcHHHHhHHHHHHHHHHcCC-cEEEEeecCCCCCCCCChhhcHHHHHH
Confidence            3477788888999999999999999998899999999999999999999999 599999999998652245899999999


Q NP_000282.1      84 ELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVN  163 (417)
Q Consensus        84 ~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVN  163 (417)
                      +|+++|+.+|.|++++++.      ..+++|+|+||||+|||++|+++               +.+|++.||+++|+|||
T Consensus        80 ~L~~~l~~~v~f~~d~~~~------~~~~~g~i~lLENlRF~~~E~~n---------------~~~fa~~La~l~DiyVn  138 (387)
T 6HXE_A           80 YLSKALGREVPLVSDYLNG------VDVKAGDIVLFENVRFNKGEKKN---------------ADELAKQYAALCDVFVM  138 (387)
T ss_dssp             HHHHHHTSCCCEESCCTTC------CCCCTTCEEEECCGGGSTTTTTT---------------CHHHHHHHHHTCSEEEE
T ss_pred             HHHHHhCCCCCccccccCC------ccCCCCcEEEEeCccCCCccccC---------------HHHHHHHHHHcccHhhc
Confidence            9999998779999865542      27889999999999999876532               36799999999999999


Q NP_000282.1     164 DAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMA  241 (417)
Q Consensus       164 DAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a  241 (417)
                      |||+++||.|||+++++  +|+++||++|++||++|++++++|+||+++|+||+|++||+++|++|++++|.|++||+||
T Consensus       139 DAF~~~HR~haS~vgi~~~l~~s~aG~l~~kEl~~L~~~l~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~iligG~~a  218 (387)
T 6HXE_A          139 DAFGTAHRAEGSTHGVAKFAKVAAAGPLLAAELDALGKALGAPAKPMAAIVAGSKVSTKLDVLNSLSQICDLLIVGGGIA  218 (387)
T ss_dssp             CCGGGTTCCCCCCCCHHHHSSEEEECHHHHHHHHHHHHHHTSCCSSEEEEEEESCTGGGHHHHHHHHTTCSEEEEEHHHH
T ss_pred             ccHhhcccccCchhhHhhccchhhHHHHHHHHHHHHHHHHcCCCCCeEEEEcCCCHHHHHHHHHHHHHHCCEEEEeChHH
Confidence            99999999999999998  6668999999999999999999999999999999999999999999999889999999999


Q NP_000282.1     242 FTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESS  321 (417)
Q Consensus       242 ~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  321 (417)
                      |+||+|+ |+++|+|++|++..+.|+++++     +++|++|+|++|.+.+..++... ......+|++|+++||||+|+
T Consensus       219 ~tfL~a~-g~~vg~S~~e~~~~~~a~~il~-----~~ki~lP~D~vv~~~~~~~~~~~-~~~~~~ip~~~~~~DIGp~Ti  291 (387)
T 6HXE_A          219 DTFLAAA-GHPVGKSLYEPDLLDTARAIAA-----KVNVPLPTDVVVAKEFAESAEAT-VKLIADVAADDMILDIGPQTA  291 (387)
T ss_dssp             HHHHHHT-TCCCCSSCCCGGGHHHHHHHHH-----HSBCCCCSEEEEESCSSTTCCCE-EEEGGGCCTTCEEEEECHHHH
T ss_pred             HHHHHHc-CCCCCccccChhHHHHHHHHHH-----cCcccccccEEEchhhhccccce-EEehhhcCCCceeecCCHHHH
Confidence            9999998 8899999999888888888864     58999999999998754322110 111237888999999999999


Q NP_000282.1     322 KKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLE  401 (417)
Q Consensus       322 ~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le  401 (417)
                      +.|+++|++|||||||||||+||+++|++||+++++++++.   ++++|+|||||+++++++|+.++++||||||||+||
T Consensus       292 ~~~~~~I~~aktI~wNGP~G~~E~~~f~~GT~~i~~al~~~---~a~~ivGGGdT~~~~~~~g~~~~~s~vSTGGGA~Le  368 (387)
T 6HXE_A          292 EHFAQLLKTSKTILWNGPVGVFEFDQFGNGTKVLAKAIADS---AAFSIAGGGDTLAAIDKYGVADQISQISTGGGAFLE  368 (387)
T ss_dssp             HHHHHHHHHCSEEEEECCSSCTTSGGGCHHHHHHHHHHHHC---SSEEEEESHHHHHHHHHHTCGGGSSEEECCHHHHHH
T ss_pred             HHHHHHHHcCCeEEEcCCCCccccCccCcHHHHHHHHHHhc---CCeEEEcCHHHHHHHHHhCCCccceEEEcchhHHHH
Confidence            99999999999999999999999888999999999999762   689999999999989988988889999999999999


Q NP_000282.1     402 LLEGKVLPGVDALSN  416 (417)
Q Consensus       402 ~L~G~~LPgl~aL~~  416 (417)
                      ||+|+.||||++|++
T Consensus       369 ~L~G~~LPgl~aL~~  383 (387)
T 6HXE_A          369 FVEGKVLPAVEVLES  383 (387)
T ss_dssp             HHTTCCCHHHHHHHH
T ss_pred             HHcCCCCchHHHHHH
Confidence            999999999999985


No 18
>4NG4_B Phosphoglycerate kinase (E.C.2.7.2.3); phosphoglycerate kinase, TRANSFERASE; HET: ADP; 2.78A {Coxiella burnetii}
Probab=100.00  E-value=4.7e-108  Score=829.99  Aligned_cols=389  Identities=41%  Similarity=0.687  Sum_probs=351.1  Template_Neff=6.400

Q NP_000282.1       1 MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEP   80 (417)
Q Consensus         1 ~~~~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~   80 (417)
                      |+...++++++.|++||+||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++.+||+|
T Consensus         9 ~~~~~~~~~~~~~l~gk~vlvR~D~NVp~~~~~i~dd~Ri~~~lpTI~~Ll~~ga-kvvl~sHlGrP~~~~~~~~~Sl~~   87 (404)
T 4NG4_B            9 MKALPFLSMSNLNLHNKRVMIREDLNVPMKNGKITNDERIVRALPTIQKAIEQKA-RVMILSHLGRPEEGKFEKEFSLAP   87 (404)
T ss_dssp             ----CCCBGGGSCCTTCEEEEEECCCCCEETTEESCCHHHHHHHHHHHHHHHTTC-EEEEEECCSCCCTTCCCGGGCSHH
T ss_pred             ccccccccccccccCCCEEEEEeecCccccCCccCCcHHHHHHHHHHHHHHHCCC-eEEEEeeccCcCCCCCcccccHHH
Confidence            5666778887788999999999999999988899999999999999999999999 599999999998753246899999


Q NP_000282.1      81 VAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDV  160 (417)
Q Consensus        81 va~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Di  160 (417)
                      |+++|+++|+.+|.|+++|++.      ..+++|+|+||||+|||++|+.+               +++|+++||+++|+
T Consensus        88 v~~~L~~~l~~~v~fv~d~~~~------~~~~~g~ilLLENlRf~~~E~~~---------------~~~fa~~La~l~Di  146 (404)
T 4NG4_B           88 VARLLSKKLNQKVPLINDWLKG------VAVEPGQAILCENVRFNKGENEN---------------NTELAKRMAELCDI  146 (404)
T ss_dssp             HHHHHHHHTC-CCCEESSGGGC------CCCCTTCEEEECCGGGSTTTTTT---------------CHHHHHHHHHTCSE
T ss_pred             HHHHHHHHhCCCCCcccccccc------ccCCCCCEEEEeccccCCccccc---------------cHHHHHHHHhcccH
Confidence            9999999998779999999873      37889999999999999976532               36799999999999


Q NP_000282.1     161 YVNDAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGG  238 (417)
Q Consensus       161 yVNDAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG  238 (417)
                      ||||||+++||.|||+++++  +|+++||++|++|+++|++++++|+||+++|+||+|++||+++|++|++++|.|+|||
T Consensus       147 yVnDAF~~~HR~~aS~~gi~~~l~~~~aG~l~~kEl~~l~~~~~~p~~P~v~IlGG~Kv~dKi~li~~Ll~~~D~iligG  226 (404)
T 4NG4_B          147 FVMDAFATAHRAQASTAGVAAYAKLACAGPLLISEVEALSRALENPQKPLVAVVGGSKVSTKIHLLENLLDKVDQLIVGG  226 (404)
T ss_dssp             EEECCGGGTTSCCCCCCCHHHHCSEEEECHHHHHHHHHHHHHHHSCCSSEEEEEEESCGGGTHHHHHHHHTTCSEEEEEE
T ss_pred             hhhcCHhHcccccccccchhhccchhhhhHHHHHHHHHHHHHHhCCCCCEEEEECCCCHHHHHHHHHHHHHhcCeEEEcC
Confidence            99999999999999999998  6658999999999999999999999999999999999999999999999999999999


Q NP_000282.1     239 GMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGP  318 (417)
Q Consensus       239 ~~a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp  318 (417)
                      +||++||+|+ |+++|+|++|++..+.|++++++|++++++|++|+|++|.+.+..++.. .......+|++|+++||||
T Consensus       227 ~~a~tFL~a~-g~~ig~S~~e~~~~~~a~~ll~~a~~~~~kI~lP~D~vv~~~~~~~~~~-~~~~~~~i~~~~~~lDIGp  304 (404)
T 4NG4_B          227 GIANTFLKAQ-GYSIGKSLCENEWLDAAQQFWEKAAEKNVSLPLPVDVIVADELSEDAKA-TVKNIDAVTSNESIFDVGP  304 (404)
T ss_dssp             HHHHHHHHHT-TCCCTTCCCCGGGHHHHHHHHHHHHHHTCBCCCCSEEEEESSCSTTSCC-EEEEGGGCCTTCEEEEECH
T ss_pred             HHHHHHHHHc-CCCcccccccchHHHHHHHHHHHHHHCCCCcCceeEEEEcccCCccccc-EeecccccCCCcccccCCH
Confidence            9999999998 8999999999999999999999999999999999999999875433221 1112247888999999999


Q NP_000282.1     319 ESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGA  398 (417)
Q Consensus       319 ~Ti~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA  398 (417)
                      +|++.|+++|++|||||||||||+||+++|++||+++++++++.   ++++|+|||||+++++++++.++++||||||||
T Consensus       305 ~Ti~~~~~~I~~aktI~wnGp~G~~E~~~f~~GT~~i~~~l~~~---~a~sivGGGDT~~~~~~~~~~~~~~~vStgGgA  381 (404)
T 4NG4_B          305 NTSATYAKLMAQAGTIVWNGPIGVFEIEAFSQGTRALAQAVAKS---TAYSIVGGGDTLAALDKFNLTDQMSYVSTAGGA  381 (404)
T ss_dssp             HHHHHHHHHHHHCSEEEEESCSSCTTSSTTCHHHHHHHHHHHHS---CSEEEECCHHHHHHHHHTTCGGGSSEECCCTHH
T ss_pred             HHHHHHHHHHHhCCEEEEeCCCCcccchhHcHHHHHHHHHHHhC---CCCEEEccHHHHHHHHHCCCCcCceEEecccHH
Confidence            99999999999999999999999999888999999999999763   689999999999999989988889999999999


Q NP_000282.1     399 SLELLEGKVLPGVDALSN  416 (417)
Q Consensus       399 ~Le~L~G~~LPgl~aL~~  416 (417)
                      +||||+|++||||++|++
T Consensus       382 ~Le~L~G~~LPgl~aL~~  399 (404)
T 4NG4_B          382 FLEFLEGKILPAIKILTQ  399 (404)
T ss_dssp             HHHHHHTCCCHHHHHHHH
T ss_pred             HHHHHcCCCChHHHHHHH
Confidence            999999999999999986


No 19
>4NG4_C Phosphoglycerate kinase (E.C.2.7.2.3); phosphoglycerate kinase, TRANSFERASE; HET: ADP; 2.78A {Coxiella burnetii}
Probab=100.00  E-value=4.7e-108  Score=829.99  Aligned_cols=389  Identities=41%  Similarity=0.687  Sum_probs=348.3  Template_Neff=6.400

Q NP_000282.1       1 MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEP   80 (417)
Q Consensus         1 ~~~~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~   80 (417)
                      |+...++++++.|++||+||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++.+||+|
T Consensus         9 ~~~~~~~~~~~~~l~gk~vlvR~D~NVp~~~~~i~dd~Ri~~~lpTI~~Ll~~ga-kvvl~sHlGrP~~~~~~~~~Sl~~   87 (404)
T 4NG4_C            9 MKALPFLSMSNLNLHNKRVMIREDLNVPMKNGKITNDERIVRALPTIQKAIEQKA-RVMILSHLGRPEEGKFEKEFSLAP   87 (404)
T ss_dssp             ----CCCBGGGSCCTTCEEEEEECCCCCEETTEESCCHHHHHHHHHHHHHHHTTC-EEEEEECCSCCCTTCCCGGGCSHH
T ss_pred             ccccccccccccccCCCEEEEEeecCccccCCccCCcHHHHHHHHHHHHHHHCCC-eEEEEeeccCcCCCCCcccccHHH
Confidence            5666778887788999999999999999988899999999999999999999999 599999999998753246899999


Q NP_000282.1      81 VAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDV  160 (417)
Q Consensus        81 va~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Di  160 (417)
                      |+++|+++|+.+|.|+++|++.      ..+++|+|+||||+|||++|+.+               +++|+++||+++|+
T Consensus        88 v~~~L~~~l~~~v~fv~d~~~~------~~~~~g~ilLLENlRf~~~E~~~---------------~~~fa~~La~l~Di  146 (404)
T 4NG4_C           88 VARLLSKKLNQKVPLINDWLKG------VAVEPGQAILCENVRFNKGENEN---------------NTELAKRMAELCDI  146 (404)
T ss_dssp             HHHHHHHHCC--CCEESSGGGC------CCCCTTCEEEECCGGGSTTTTTT---------------CHHHHHHHHHTCSE
T ss_pred             HHHHHHHHhCCCCCcccccccc------ccCCCCCEEEEeccccCCccccc---------------cHHHHHHHHhcccH
Confidence            9999999998779999999873      37889999999999999976532               36799999999999


Q NP_000282.1     161 YVNDAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGG  238 (417)
Q Consensus       161 yVNDAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG  238 (417)
                      ||||||+++||.|||+++++  +|+++||++|++|+++|++++++|+||+++|+||+|++||+++|++|++++|.|+|||
T Consensus       147 yVnDAF~~~HR~~aS~~gi~~~l~~~~aG~l~~kEl~~l~~~~~~p~~P~v~IlGG~Kv~dKi~li~~Ll~~~D~iligG  226 (404)
T 4NG4_C          147 FVMDAFATAHRAQASTAGVAAYAKLACAGPLLISEVEALSRALENPQKPLVAVVGGSKVSTKIHLLENLLDKVDQLIVGG  226 (404)
T ss_dssp             EEECCGGGTTSCCCCCCCHHHHCSEEEECHHHHHHHHHHHHHHHSCCSSEEEEEEESCGGGTHHHHHHHHTTCSEEEEEE
T ss_pred             hhhcCHhHcccccccccchhhccchhhhhHHHHHHHHHHHHHHhCCCCCEEEEECCCCHHHHHHHHHHHHHhcCeEEEcC
Confidence            99999999999999999998  6658999999999999999999999999999999999999999999999999999999


Q NP_000282.1     239 GMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGP  318 (417)
Q Consensus       239 ~~a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp  318 (417)
                      +||++||+|+ |+++|+|++|++..+.|++++++|++++++|++|+|++|.+.+..++.. .......+|++|+++||||
T Consensus       227 ~~a~tFL~a~-g~~ig~S~~e~~~~~~a~~ll~~a~~~~~kI~lP~D~vv~~~~~~~~~~-~~~~~~~i~~~~~~lDIGp  304 (404)
T 4NG4_C          227 GIANTFLKAQ-GYSIGKSLCENEWLDAAQQFWEKAAEKNVSLPLPVDVIVADELSEDAKA-TVKNIDAVTSNESIFDVGP  304 (404)
T ss_dssp             HHHHHHHHHT-TCCCTTCCCCGGGHHHHHHHHHHHHHHTCBCCCCSEEEEESSCSTTSCC-EEEEGGGCCTTCEEEEECH
T ss_pred             HHHHHHHHHc-CCCcccccccchHHHHHHHHHHHHHHCCCCcCceeEEEEcccCCccccc-EeecccccCCCcccccCCH
Confidence            9999999998 8999999999999999999999999999999999999999875433221 1112247888999999999


Q NP_000282.1     319 ESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGA  398 (417)
Q Consensus       319 ~Ti~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA  398 (417)
                      +|++.|+++|++|||||||||||+||+++|++||+++++++++.   ++++|+|||||+++++++++.++++||||||||
T Consensus       305 ~Ti~~~~~~I~~aktI~wnGp~G~~E~~~f~~GT~~i~~~l~~~---~a~sivGGGDT~~~~~~~~~~~~~~~vStgGgA  381 (404)
T 4NG4_C          305 NTSATYAKLMAQAGTIVWNGPIGVFEIEAFSQGTRALAQAVAKS---TAYSIVGGGDTLAALDKFNLTDQMSYVSTAGGA  381 (404)
T ss_dssp             HHHHHHHHHHHHCSEEEEESCSSCTTSSGGGHHHHHHHHHHHHS---CSEEEECCHHHHHHHHHTTCGGGSSEECCCTHH
T ss_pred             HHHHHHHHHHHhCCEEEEeCCCCcccchhHcHHHHHHHHHHHhC---CCCEEEccHHHHHHHHHCCCCcCceEEecccHH
Confidence            99999999999999999999999999888999999999999763   689999999999999989988889999999999


Q NP_000282.1     399 SLELLEGKVLPGVDALSN  416 (417)
Q Consensus       399 ~Le~L~G~~LPgl~aL~~  416 (417)
                      +||||+|++||||++|++
T Consensus       382 ~Le~L~G~~LPgl~aL~~  399 (404)
T 4NG4_C          382 FLEFLEGKILPAIKILTQ  399 (404)
T ss_dssp             HHHHHHC--CHHHHHHHH
T ss_pred             HHHHHcCCCChHHHHHHH
Confidence            999999999999999986


No 20
>6I06_A Phosphoglycerate kinase (E.C.2.7.2.3); hinge binding, TRANSFERASE, kinase, glycolysis; 2.0A {Pseudomonas}
Probab=100.00  E-value=1e-107  Score=823.37  Aligned_cols=381  Identities=39%  Similarity=0.687  Sum_probs=326.8  Template_Neff=6.400

Q NP_000282.1       4 SNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAV   83 (417)
Q Consensus         4 ~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~   83 (417)
                      |.++++++.|++|||||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++.+||+||++
T Consensus         1 ~~~~~l~~~~l~gK~vlvR~D~NVPl~~~~i~d~~RI~~~lpTI~~L~~~ga-kvil~sHlGrP~g~~~~~~~Sl~~va~   79 (387)
T 6I06_A            1 MTVLKMTDLDLQGKRVLIREDLNVPVKDGVVTSDARILASLPTIKLALEKGA-AVMVCSHLGRPTEGEFSAENSLKPVAD   79 (387)
T ss_dssp             CCBGG--GSCCTTCEEEEECCCCCCBSSSCBSCCHHHHHHHHHHHHHHHTTC-EEEEECCCSCCCTTSCCGGGCSHHHHH
T ss_pred             CCCccCChHHcCCCEEEEEeecCcccCCCCCCCcHHHHHHHHHHHHHHHCCC-cEEEEeecCCCCCCCCCcccchHHHHH
Confidence            3467777788999999999999999998899999999999999999999999 599999999998652235799999999


Q NP_000282.1      84 ELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVN  163 (417)
Q Consensus        84 ~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVN  163 (417)
                      +|+++|+.+|.|+++++..      ..+++|+|+||||+|||++|+++               +.+|++.||+++|+|||
T Consensus        80 ~L~~~l~~~v~f~~~~~~~------~~l~~g~illLENlRF~~~E~~n---------------~~~fa~~La~l~DiyVn  138 (387)
T 6I06_A           80 YLSKALGREVPLVSDYLNG------VDVKAGDIVLFENVRFNKGEKKN---------------ADELAKQYAALCDVFVM  138 (387)
T ss_dssp             HHHHHHTSCCCEESCCTTC------CCCCTTCEEEECCGGGSTTTTTT---------------CHHHHHHHHHTCSEEEE
T ss_pred             HHHHHHCCCceecCCCCCC------ccCCCCcEEEEeCcccCCCcccC---------------CHHHHHHHHhhccHhhc
Confidence            9999998778999855442      26889999999999999876532               36799999999999999


Q NP_000282.1     164 DAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMA  241 (417)
Q Consensus       164 DAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a  241 (417)
                      |||+++||.|||+++++  +|+++||++|++|+++|++++++|+||+++|+||+|++||+++|++|++++|.|++||+||
T Consensus       139 DAF~~~HR~~aS~vgi~~~lp~s~aG~l~~kEl~~L~~~~~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~iligG~~a  218 (387)
T 6I06_A          139 DAFGTAHRAEGSTHGVAKFAKVAAAGPLLAAELDALGKALGAPAKPMAAIVAGSKVSTKLDVLNSLSQICDLLIVGGGIA  218 (387)
T ss_dssp             CCGGGTTSCCCCCCCHHHHSSEEEECHHHHHHHHHHHHHHSSCCSSEEEEEEESCTGGG--HTCSEE------EEEHHHH
T ss_pred             ccHhhcccccccccccccCCCchhhhHHHHHHHHHHHHHHhCCCCCEEEEEcCCCHHHHHHHHHHHHHcCCEEEEcChHH
Confidence            99999999999999998  6668999999999999999999999999999999999999999999999889999999999


Q NP_000282.1     242 FTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESS  321 (417)
Q Consensus       242 ~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  321 (417)
                      |+||+|+ |+++|+|++|++..+.|+++++     +++|++|+|++|.+.+..+.... .....++|++|+++||||+|+
T Consensus       219 ~tfL~a~-g~~vg~S~~e~~~~~~a~~il~-----~~ki~lP~D~vv~~~~~~~~~~~-~~~~~~ip~~~~~~DIGp~Ti  291 (387)
T 6I06_A          219 DTFLAAA-GHPVGKSLYEPDLLDTARAIAA-----KVNVPLPTDVVVAKEFAESAEAT-VKLIADVAADDMILDIGPQTA  291 (387)
T ss_dssp             HHHHHHT-TCCCBSCCCCGGGHHHHHHHHH-----HSBCCCCSEEEEESCSSTTCCCE-ECCTTC-----EEEEECHHHH
T ss_pred             HHHHHHc-CCcccccccchhHHHHHHHHHh-----cCeEEcccCEEecccCCCCCCcc-eeccccCCCCceeecCCHHHH
Confidence            9999998 8889999999888888888764     68999999999998653321110 111237888999999999999


Q NP_000282.1     322 KKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLE  401 (417)
Q Consensus       322 ~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le  401 (417)
                      +.|+++|++|||||||||||+||+++|++||+++++++++.   ++++|+|||||+++++++|+.++++||||||||+||
T Consensus       292 ~~~~~~I~~aktI~wnGp~G~~E~~~f~~GT~~i~~ai~~~---~a~~ivGGGdT~~~~~~~g~~~~~~~vStgGGA~L~  368 (387)
T 6I06_A          292 EHFAQLLKTSKTILWNGPVGVFEFDQFGNGTKVLAKAIADS---AAFSIAGGGDTLAAIDKYGVADQISYISTGGGAFLE  368 (387)
T ss_dssp             HHHHHHHHTCSEEEEECCSBCTTSGGGCHHHHHHHHHHHHS---CSEEEEESHHHHHHHHHHTCGGGSSEEECCTHHHHH
T ss_pred             HHHHHHHHhCCEEEEeCCCChhcCCccchHHHHHHHHHHhC---CCcEEEcCHHHHHHHHHcCCccCcEEEEechHHHHH
Confidence            99999999999999999999999888999999999999762   689999999999999988988889999999999999


Q NP_000282.1     402 LLEGKVLPGVDALSN  416 (417)
Q Consensus       402 ~L~G~~LPgl~aL~~  416 (417)
                      ||+|++||||++|++
T Consensus       369 ~L~G~~LPgl~aL~~  383 (387)
T 6I06_A          369 FVEGKVLPAVEVLES  383 (387)
T ss_dssp             HHTTCCCHHHHHHHH
T ss_pred             HHcCCCCchHHHHhH
Confidence            999999999999975


No 21
>2CUN_A Phosphoglycerate kinase (E.C.2.7.2.3); Phosphoglycerate kinase, Structural Genomics, TANPAKU; HET: 3PG, MPD, GOL; 2.1A {Pyrococcus horikoshii}
Probab=100.00  E-value=3.4e-105  Score=811.02  Aligned_cols=387  Identities=33%  Similarity=0.531  Sum_probs=341.8  Template_Neff=6.500

Q NP_000282.1       8 TLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKS   87 (417)
Q Consensus         8 ~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~~L~~   87 (417)
                      +++|.|++||+||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++.   .+|++||+++|++
T Consensus         3 ~~~~~~l~gK~vlvR~D~Nvpl~~~~i~d~~Ri~~~lpTI~~Ll~~ga-kvvl~sH~GrP~~~~---~~sl~~v~~~L~~   78 (410)
T 2CUN_A            3 RLEDFNFHNKTVFLRVDLNSPMKDGKIISDARFKAVLPTIRYLIESGA-KVVIGTHQGKPYSED---YTTTEEHARVLSE   78 (410)
T ss_dssp             BGGGSCCTTCEEEEECCCCCCEETTEECCCHHHHHTHHHHHHHHHTTC-EEEEECCCSCTTCTT---CCCSHHHHHHHHH
T ss_pred             ccccccCCCCEEEEEeeCCCcccCCCCCCcHHHHHHHHHHHHHHHCCC-cEEEEeccCCCCCCC---CCCHHHHHHHHHH
Confidence            456678999999999999999998899999999999999999999999 599999999998753   6899999999999


Q NP_000282.1      88 LLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFG  167 (417)
Q Consensus        88 ~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVNDAFg  167 (417)
                      +|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|++++++        +++++..|++.||+++|+||||||+
T Consensus        79 ~l~~~v~f~~~~~g~~~~~~i~~~~~g~illLENlRF~~~E~~~~~~--------~~~~~~~fa~~La~l~DiyVnDAF~  150 (410)
T 2CUN_A           79 LLDQHVEYIEDIFGRYAREKIKELKSGEVAILENLRFSAEEVKNKPI--------EECEKTFLVKKLSKVIDYVVNDAFA  150 (410)
T ss_dssp             HHTSCEEECSCSSSHHHHHHHHTCCTTCEEECSCGGGBTTTTSCCCH--------HHHTTSHHHHHHHTTCSEEEECCGG
T ss_pred             HHcCcEEehhhccChhHHHHHHHccCCCEEEEeccccchhHhcCCCh--------hHhHHHHHHHHHhccCCEEEecccc
Confidence            99877999999999888888899999999999999999977643110        0112356999999999999999999


Q NP_000282.1     168 TAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLD--KVNEMIIGGGMAFT  243 (417)
Q Consensus       168 ~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~--~~D~iligG~~a~t  243 (417)
                      ++||.|||+++++  +| ++||++|++||++|++++++|+||+++|+||+|++||+++|++|++  +||.|++||+||++
T Consensus       151 ~~HR~~aS~vgi~~~lp-s~aG~l~~kEl~~L~~~~~~p~rP~v~IlGG~KvsdKi~li~~Ll~~~~vD~IligG~~a~~  229 (410)
T 2CUN_A          151 TAHRSQPSLVGFARIKP-MIMGFLMEKEIEALMRAYYSKDSPKIYVLGGAKVEDSLKVVENVLRRERADLVLTGGLVANV  229 (410)
T ss_dssp             GTTCCCHHHHTTTTTSC-EEECHHHHHHHHHHHHHHTCCCSCEEEEECSSCHHHHHHHHHHHHHTTSCSEEEECHHHHHH
T ss_pred             cccCCCcchhhHHhhch-HHhcHHHHHHHHHHHHHHhCCCCCcEEEECCCCHHHHHHHHHHHHHHHhCCEEEEchhHHHH
Confidence            9999999999998  66 8999999999999999999999999999999999999999999996  78999999999999


Q NP_000282.1     244 FLKVLNNMEIGTSLFDEE-------GAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDC  316 (417)
Q Consensus       244 fl~a~~g~~ig~s~~e~~-------~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DI  316 (417)
                      ||+|+ |+++|+|++|++       ..+.|+++++.   ++++|++|+||+|.++... ...........+|++|+++||
T Consensus       230 fL~a~-g~~ig~s~~e~~~~~~~~~~~~~a~~il~~---~~~~I~lPvD~~v~~~~~~-~~~~~~~~~~~ip~~~~~~DI  304 (410)
T 2CUN_A          230 FTLAK-GFDLGRKNVEFMKKKGLLDYVKHAEEILDE---FYPYIRTPVDFAVDYKGER-VEIDLLSENRGLLHQYQIMDI  304 (410)
T ss_dssp             HHHHH-TCCCCHHHHHHHHTTTGGGGHHHHHHHHHH---HGGGEECCSEEEEEETTEE-EEEESSSGGGGGGGTSCEEEE
T ss_pred             HHHHc-CCCCCcchHHHhHhhCHHHHHHHHHHHHHH---HCCccccceeEEecCCCCc-ceeeeeccccCCCCCceeecC
Confidence            99998 899999987763       34555555542   6889999999999886432 111011122478899999999


Q NP_000282.1     317 GPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGG  396 (417)
Q Consensus       317 Gp~Ti~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgG  396 (417)
                      ||+|++.|+++|++|||||||||||+||+++|++||++++++++++   ++++|+|||||+++++++|+. +++||||||
T Consensus       305 Gp~Ti~~~~~~I~~aktI~wnGP~G~~E~e~f~~GT~~i~~ai~~~---~a~~vvGGGdT~~~~~~~g~~-~~s~vStgG  380 (410)
T 2CUN_A          305 GKRTAEKYREILMKARIIVANGPMGVFEREEFAIGTVEVFKAIADS---PAFSVLGGGHSIASIQKYGIT-GITHISTGG  380 (410)
T ss_dssp             CHHHHHHHHHHHHTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHS---SSEEEEECGGGGGGGGGSCCC-CCSEECSCS
T ss_pred             CHHHHHHHHHHHhhCCEEEEeCCCCcccchhhchhHHHHHHHHHcC---CCEEEEecHHHHHHHHHhCCC-CcEEEEecc
Confidence            9999999999999999999999999999888999999999999763   689999999999999888875 799999999


Q NP_000282.1     397 GASLELLEGKVLPGVDALSN  416 (417)
Q Consensus       397 gA~Le~L~G~~LPgl~aL~~  416 (417)
                      ||+||||+|+.||||++|++
T Consensus       381 gA~Le~L~G~~LPgl~aL~~  400 (410)
T 2CUN_A          381 GAMLSFFAGEELPVLRALQI  400 (410)
T ss_dssp             HHHHHHHTTCCCHHHHHHHH
T ss_pred             hHHHHHHcCCCChHHHHHHH
Confidence            99999999999999999975


No 22
>1FW8_A PHOSPHOGLYCERATE KINASE (E.C.2.7.2.3); phosphotransferase, kinase, phosphoglycerate kinase, glycolysis; HET: GOL; 2.3A {Saccharomyces cerevisiae} SCOP: c.86.1.1
Probab=100.00  E-value=8.8e-90  Score=698.26  Aligned_cols=342  Identities=68%  Similarity=1.065  Sum_probs=299.2  Template_Neff=6.400

Q NP_000282.1      74 DKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRAS  153 (417)
Q Consensus        74 ~~~Sl~~va~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~  153 (417)
                      +.+||+||+++|+++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|+++.++ ++.+.+++++++.+|++.
T Consensus         2 ~~~Sl~pva~~L~~ll~~~V~f~~d~~g~~~~~~i~~~~~g~IllLENlRF~~~E~~~~~~-n~~~~~~~~~~~~~fa~~   80 (416)
T 1FW8_A            2 SKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRKV-DGQKVKASKEDVQKFRHE   80 (416)
T ss_dssp             CTTCSHHHHHHHHHHHTSCEEECSCSSSHHHHHHHHTSCTTEEEECCCGGGSHHHHSEEEE-TTEEEECCHHHHHHHHHH
T ss_pred             CCccHHHHHHHHHHHHCCceeeccCCCCHHHHHHHHhcCCCCEEEEecceecccccccccc-CCcccccCHHHHHHHHHH
Confidence            3689999999999999877999999999888888899999999999999999977632100 000001112234789999


Q NP_000282.1     154 LSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNE  233 (417)
Q Consensus       154 LA~l~DiyVNDAFg~aHR~~aS~~gi~l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~  233 (417)
                      ||+++|+|||||||++||.|||++++++|+++||++|++||++|++++++|+||+++|+||+|++||+++|++|+++||.
T Consensus        81 La~l~diyVnDAFg~~HR~~aS~vgi~lp~s~aG~ll~kEi~~L~kil~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~  160 (416)
T 1FW8_A           81 LSSLADVYINDAFGTAHRAHSSMVGFDLPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDS  160 (416)
T ss_dssp             HHTTCSEEEECCGGGTTSCCHHHHCCCCSCEEECHHHHHHHHHHHHHHHSCCSSEEEEEECSCSTTTHHHHHHHHTTCSE
T ss_pred             HHhhCCeEeecccccCCccccCcccCCCchhhhcHHHHHHHHHHHHHhhCCCCCEEEEEcCCCHHHHHHHHHHHHHhcCE
Confidence            99999999999999999999999999976589999999999999999999999999999999999999999999999999


Q NP_000282.1     234 MIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMG  313 (417)
Q Consensus       234 iligG~~a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~  313 (417)
                      |++||+|||+||+|++++++|+|++|++..+.|++++++|+.++++|+||+|++|.+.+..+.....+...+.+|++|++
T Consensus       161 IligG~~a~tfL~a~~~~~iG~S~~e~~~~~~a~~il~~a~~~~~ki~LP~D~vv~~~~~~~~~~~~~~~~~~i~~~~~i  240 (416)
T 1FW8_A          161 IIIGGGMAFTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEGIPAGWQG  240 (416)
T ss_dssp             EEEEGGGHHHHHHHHSCCCCCSCCCCHHHHHHHHHHHHHHHHHTCEEECCSEEEEESSSSTTCCEEEEETTTCCCTTCEE
T ss_pred             EEeCchHHHHHHHHhCCCccCccccchhhhhHHHHHHHHHHHcCCeEEeeeeEEEeccccCCCCCceeeccCCCCCCCcc
Confidence            99999999999999755689999999988999999999988999999999999998865322211111122378899999


Q NP_000282.1     314 LDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVS  393 (417)
Q Consensus       314 ~DIGp~Ti~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vS  393 (417)
                      +||||+|++.|.+.|++|||||||||||+||.++|++||+++++++++++.+++++|+|||||+++++++|+.++++|||
T Consensus       241 lDIGp~Ti~~~~~~I~~aktI~wnGP~G~~E~~~f~~GT~~i~~ai~~~~~~~a~~ivGGGdT~~~~~~~g~~~~~s~vS  320 (416)
T 1FW8_A          241 LDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVS  320 (416)
T ss_dssp             EEECHHHHHHHHHHHHHCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHHHHTTCEEEECTTHHHHHHHHTTCGGGSSEEC
T ss_pred             cccCHHHHHHHHHHHHcCCEEEEcCCCCcccccccChHHHHHHHHHHHHhcCCCeEEEechhHHHHHHHhCCCCCceEEe
Confidence            99999999999999999999999999999998889999999999997632236899999999999998889878899999


Q NP_000282.1     394 TGGGASLELLEGKVLPGVDALSN  416 (417)
Q Consensus       394 tgGgA~Le~L~G~~LPgl~aL~~  416 (417)
                      |||||+||||+|+.||||++|++
T Consensus       321 TGGGA~Le~L~Gk~LPgieaL~~  343 (416)
T 1FW8_A          321 TGGGASLELLEGKELPGVAFLSE  343 (416)
T ss_dssp             SCSHHHHHHHTTCCCHHHHTSCS
T ss_pred             cCchHHHHHHcCCCCCceeehhh
Confidence            99999999999999999999985


No 23
>1FW8_A PHOSPHOGLYCERATE KINASE (E.C.2.7.2.3); phosphotransferase, kinase, phosphoglycerate kinase, glycolysis; HET: GOL; 2.3A {Saccharomyces cerevisiae} SCOP: c.86.1.1
Probab=99.28  E-value=3.2e-16  Score=156.69  Aligned_cols=68  Identities=57%  Similarity=0.940  Sum_probs=61.4  Template_Neff=6.400

Q NP_000282.1       3 LSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGV   70 (417)
Q Consensus         3 ~~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~   70 (417)
                      ++.++++++.+++|||||||+|+|||+++++|.|++||++++|||+||+++||++||++||+|||+++
T Consensus       347 ~~~~~~~~~~~~~~k~vl~R~D~nvp~~~~~i~d~~Ri~~~~~ti~~l~~~~~~~vii~sH~grp~~~  414 (416)
T 1FW8_A          347 LSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRPNGE  414 (416)
T ss_dssp             SSCSCBGGGSCCTTCEEEEECCCCCCBSSSSBSCTHHHHHHHHHHHHHHHTCCSEEEEECCCSCCCSS
T ss_pred             ccccccccccccCCCEEEEEeecCCCCCCCCcCCCHHHHhHHHHHHHHHHcCCCEEEEeeccCCCCCC
Confidence            45567777788999999999999999988899999999999999999999998449999999999875


No 24
>2Q33_B D-MONELLIN CHAIN A, D-MONELLIN CHAIN; ALPHA/BETA, ALL-D PROTEIN, DE NOVO; 1.8A {N/A}
Probab=34.33  E-value=5.9  Score=24.60  Aligned_cols=11  Identities=36%  Similarity=0.761  Sum_probs=9.2  Template_Neff=1.000

Q NP_000282.1     310 GWMGLDCGPES  320 (417)
Q Consensus       310 ~~~~~DIGp~T  320 (417)
                      .|.++||||-|
T Consensus         2 eweiidigpft   12 (48)
T 2Q33_B            2 EWEIIDIGPFT   12 (48)
Confidence            58899999955