annotate test-data/NP_000290.2.hhr @ 0:d30785e31577 draft

"planemo upload commit 6eee67778febed82ddd413c3ca40b3183a3898f1"

Query         NP_000290.2
Match_columns 747
No_of_seqs    3849 out of 40250
Neff          6.23432
Searched_HMMs 998
Date          Fri Jul 24 20:45:58 2020
Command       /home/guerler/hh-suite/build/bin/hhblits -i /home/guerler/human/fasta/NP_00/NP_000290.2.fasta -d /home/guerler/pdb70/pdb70 -o /home/guerler/human/hhr/NP_00/NP_000290.2.hhr 

 No Hit                             Prob E-value P-value  Score    SS Cols Query HMM  Template HMM
  1 1XM9_A plakophilin 1  Plakophi  99.7 6.3E-22 7.3E-26  206.9   0.0  453  246-719     3-455 (457)
  2 3L6X_A Catenin delta-1, E-cadh  99.4 1.1E-17 1.2E-21  185.5   0.0  438  245-729    48-492 (584)
  3 5D5K_C Importin subunit alpha-  98.6 1.1E-11 1.4E-15  126.2   0.0  369  243-713    11-386 (466)
  4 3NMZ_A APC variant protein, Rh  98.6 1.3E-11 1.4E-15  129.0   0.0  381  238-715    25-452 (458)
  5 4UAF_B Importin alpha 1 import  98.5 1.3E-11 1.6E-15  125.7   0.0  369  243-713    11-386 (466)
  6 4U5L_A deltaIBB-importin-alpha  98.5 1.7E-11   2E-15  123.0   0.0  360  246-712    49-425 (426)
  7 6SA7_B DARPin-Armadillo fusion  98.5 2.5E-11 2.9E-15  127.0   0.0  136  244-380   172-309 (510)
  8 4RV1_D Engineered Protein OR49  98.5 2.7E-11 3.2E-15  120.8   0.0  362  247-715     4-369 (420)
  9 6S9O_F designed Armadillo repe  98.5 2.8E-11 3.3E-15  117.9   0.0  167  545-724   170-338 (344)
 10 5MFD_C YIIIM''6AII, Capsid dec  98.5   3E-11 3.5E-15  116.2   0.0  318  246-712     5-326 (328)
 11 4MZ6_E Deoxyuridine 5'-triphos  98.5 3.5E-11   4E-15  125.0   0.0  368  244-713    56-430 (509)
 12 5UMZ_B Importin subunit alpha-  98.5 3.5E-11   4E-15  125.0   0.0  368  244-713    56-430 (509)
 13 2JDQ_A IMPORTIN ALPHA-1 SUBUNI  98.4 3.6E-11 4.2E-15  122.1   0.0  367  244-716    19-393 (450)
 14 4E4V_A Importin subunit alpha-  98.4 3.6E-11 4.2E-15  124.3   0.0  364  246-716    76-456 (485)
 15 4B18_A IMPORTIN SUBUNIT ALPHA-  98.4   4E-11 4.7E-15  121.6   0.0  368  244-717    16-391 (447)
 16 4XZR_B Heh1-NLS, Kap60; karyop  98.4 4.3E-11   5E-15  119.8   0.0  363  248-717     4-375 (423)
 17 5XZX_A Importin subunit alpha-  98.4 4.3E-11 5.1E-15  119.5   0.0  133  247-380     4-140 (416)
 18 1JDH_A BETA-CATENIN, hTcf-4; B  98.4 4.4E-11 5.2E-15  123.9   0.0  378  245-726   101-502 (529)
 19 3IFQ_A plakoglobin, E-cadherin  98.4 4.5E-11 5.3E-15  124.5   0.0  381  246-726   104-503 (553)
 20 4UAD_A Importin alpha import a  98.4   6E-11   7E-15  121.8   0.0  372  246-723    68-456 (479)
 21 5ZHX_D Rap1 GTPase-GDP dissoci  98.4 6.3E-11 7.5E-15  120.9   0.0  407  246-727    19-458 (487)
 22 1EE4_A KARYOPHERIN ALPHA; ARM   98.4 8.2E-11 9.6E-15  117.7   0.0  364  247-717     3-375 (423)
 23 1EE4_B KARYOPHERIN ALPHA; ARM   98.4 8.2E-11 9.6E-15  117.7   0.0  364  247-717     3-375 (423)
 24 4EV8_A Catenin beta-1; mouse c  98.3 9.8E-11 1.2E-14  121.5   0.0  382  246-727   103-504 (538)
 25 4RXH_B Importin subunit alpha,  98.3 1.1E-10 1.2E-14  121.7   0.0  365  246-716    72-457 (495)
 26 4BQK_A IMPORTIN SUBUNIT ALPHA-  98.3 1.2E-10 1.3E-14  118.5   0.0  366  246-716    46-427 (456)
 27 6BW9_A Importin subunit alpha-  98.3 1.3E-10 1.5E-14  118.5   0.0  366  246-717    53-428 (459)
 28 1WA5_B GTP-BINDING NUCLEAR PRO  98.3 1.9E-10 2.2E-14  121.4   0.0  134  245-379   173-308 (530)
 29 5XGC_A Rap1 GTPase-GDP dissoci  98.3   2E-10 2.3E-14  117.7   0.0  409  246-729    35-476 (503)
 30 4BPL_A IMPORTIN SUBUNIT ALPHA-  98.2 2.4E-10 2.9E-14  115.9   0.0  367  246-717    44-426 (454)
 31 4B8J_A IMPORTIN SUBUNIT ALPHA-  98.2 2.6E-10 2.9E-14  120.0   0.0  367  246-717   118-500 (528)
 32 5T94_B Guanine nucleotide exch  98.2 2.9E-10 3.3E-14  120.5   0.0  364  246-716   131-513 (542)
 33 4TNM_A Importin-alpha3 / MOS6;  98.2 3.2E-10 3.7E-14  119.6   0.0  369  246-719   119-504 (531)
 34 5TBK_C Importin subunit alpha-  98.2 3.4E-10 3.8E-14  119.3   0.0  366  245-716    71-443 (521)
 35 5TBK_D Importin subunit alpha-  98.2 3.4E-10 3.8E-14  119.3   0.0  366  245-716    71-443 (521)
 36 2Z6G_A B-catenin; Full-Length,  98.1 6.4E-10 6.8E-14  126.7   0.0  381  245-725   234-634 (780)
 37 1JDH_A BETA-CATENIN, hTcf-4; B  98.1 6.1E-10 7.2E-14  115.0   0.0  326  286-717    16-343 (529)
 38 2Z6H_A Catenin beta-1; Beta-Ca  98.1 7.3E-10 8.1E-14  121.3   0.0  378  246-673    99-530 (644)
 39 6SA8_A ring-like DARPin-Armadi  98.1 7.7E-10 8.7E-14  121.2   0.0  342  244-691   177-522 (671)
 40 4RXH_B Importin subunit alpha,  98.1 1.2E-09 1.4E-13  113.4   0.0  157  545-714   196-354 (495)
 41 5XJG_A Vacuolar protein 8, Nuc  98.0 1.3E-09 1.5E-13  111.8   0.0  133  246-380   159-293 (506)
 42 6KBM_A Vacuolar protein 8, Aut  98.0 1.3E-09 1.5E-13  111.8   0.0  133  246-380   159-293 (506)
 43 4TNM_A Importin-alpha3 / MOS6;  98.0   2E-09 2.3E-13  113.3   0.0  158  545-714   243-402 (531)
 44 6KBN_A Vacuolar protein 8, Aut  98.0 2.1E-09 2.5E-13  112.9   0.0  133  246-380   153-287 (563)
 45 6KBN_C Vacuolar protein 8, Aut  98.0 2.1E-09 2.5E-13  112.9   0.0  133  246-380   153-287 (563)
 46 4EV8_A Catenin beta-1; mouse c  98.0 2.1E-09 2.5E-13  111.1   0.0  323  286-716    17-343 (538)
 47 4BPL_A IMPORTIN SUBUNIT ALPHA-  98.0 2.2E-09 2.5E-13  108.6   0.0  158  545-714   168-327 (454)
 48 4PLS_B Arm00010; PEPTIDE BINDI  98.0 2.5E-09 2.9E-13  100.1   0.0  112  247-359     3-114 (281)
 49 5Z8H_A Adenomatous polyposis c  98.0 2.6E-09   3E-13  104.9   0.0  123  258-380    92-219 (339)
 50 2Z6H_A Catenin beta-1; Beta-Ca  98.0 2.8E-09 3.1E-13  116.5   0.0  415  246-726    57-499 (644)
 51 5AEI_B DESIGNED ARMADILLO REPE  97.9 2.9E-09 3.4E-13   99.9   0.0  114  246-360     5-118 (286)
 52 4B8J_A IMPORTIN SUBUNIT ALPHA-  97.9 3.2E-09 3.7E-13  111.3   0.0  160  544-715   199-360 (528)
 53 4R10_A Protein humpback-2, Cad  97.9 4.1E-09 4.8E-13  110.8   0.0  417  245-725    73-531 (572)
 54 5XJG_A Vacuolar protein 8, Nuc  97.9 4.2E-09   5E-13  107.7   0.0  359  246-716    39-399 (506)
 55 6KBM_A Vacuolar protein 8, Aut  97.9 4.2E-09   5E-13  107.7   0.0  359  246-716    39-399 (506)
 56 5IZA_A Adenomatous polyposis c  97.9 4.5E-09   5E-13  105.1   0.0  297  236-625    23-335 (354)
 57 4R0Z_A Protein humpback-2; arm  97.9 5.4E-09 6.2E-13  112.3   0.0  401  246-718   115-565 (629)
 58 4R0Z_A Protein humpback-2; arm  97.9 5.5E-09 6.3E-13  112.2   0.0  418  245-726    73-532 (629)
 59 1XM9_A plakophilin 1  Plakophi  97.8 6.1E-09   7E-13  106.4   0.0  350  245-671    44-450 (457)
 60 4I2Z_A Protein UNC-45, Heat sh  97.8 7.3E-09 7.1E-13  122.5   0.0   69  247-316   648-716 (961)
 61 6SWY_5 Vacuolar import and deg  97.8 7.4E-09 7.2E-13  121.9   0.0  402  240-720   281-784 (921)
 62 5IZ8_A Adenomatous polyposis c  97.8 6.6E-09 7.4E-13  103.8   0.0  297  236-625    23-335 (354)
 63 3IFQ_A plakoglobin, E-cadherin  97.8 6.4E-09 7.5E-13  107.7   0.0  374  244-725    18-399 (553)
 64 4I2W_A Protein UNC-45, Heat sh  97.8 7.9E-09 7.7E-13  122.2   0.0   70  246-316   647-716 (961)
 65 4R10_A Protein humpback-2, Cad  97.8 8.7E-09   1E-12  108.2   0.0  398  246-715   115-562 (572)
 66 5T94_B Guanine nucleotide exch  97.8 9.3E-09 1.1E-12  108.5   0.0  159  544-715   254-414 (542)
 67 6KBN_A Vacuolar protein 8, Aut  97.8 9.2E-09 1.1E-12  107.8   0.0  358  245-714    32-391 (563)
 68 6KBN_C Vacuolar protein 8, Aut  97.8 9.2E-09 1.1E-12  107.8   0.0  358  245-714    32-391 (563)
 69 2Z6G_A B-catenin; Full-Length,  97.8 1.2E-08 1.3E-12  115.8   0.0  373  244-724   149-529 (780)
 70 5EWP_B Uncharacterized protein  97.7 1.3E-08 1.5E-12   96.8   0.0  118  263-381    60-181 (252)
 71 5XGC_A Rap1 GTPase-GDP dissoci  97.7 1.3E-08 1.6E-12  103.5   0.0  358  257-715     5-373 (503)
 72 6BW9_A Importin subunit alpha-  97.7 1.6E-08 1.9E-12  102.4   0.0  367  244-716     8-381 (459)
 73 5D5K_C Importin subunit alpha-  97.7   2E-08 2.4E-12  101.3   0.0  364  246-716    57-437 (466)
 74 4UAF_B Importin alpha 1 import  97.6 2.4E-08 2.9E-12  100.7   0.0  364  246-716    57-437 (466)
 75 3L6X_A Catenin delta-1, E-cadh  97.6 2.7E-08 2.9E-12  108.4   0.0  364  263-713    26-432 (584)
 76 4U5L_A deltaIBB-importin-alpha  97.6 2.9E-08 3.5E-12   98.5   0.0  367  245-713     5-378 (426)
 77 4MZ6_E Deoxyuridine 5'-triphos  97.6 3.4E-08   4E-12  101.6   0.0  364  246-716   101-481 (509)
 78 5UMZ_B Importin subunit alpha-  97.6 3.4E-08   4E-12  101.6   0.0  364  246-716   101-481 (509)
 79 5ZHX_D Rap1 GTPase-GDP dissoci  97.6 3.6E-08 4.2E-12   99.7   0.0  332  282-715    13-357 (487)
 80 3NOW_A SD10334p; Armadillo Rep  97.6 3.6E-08 4.2E-12  107.8   0.0  135  244-380   289-431 (810)
 81 4EV8_A Catenin beta-1; mouse c  97.5 4.1E-08 4.9E-12  100.9   0.0  137  245-381   267-409 (538)
 82 5Z8H_A Adenomatous polyposis c  97.5 4.4E-08   5E-12   95.7   0.0  161  544-716   162-332 (339)
 83 3SL9_B Catenin beta-1, B-cell   97.5 4.8E-08 5.5E-12   84.8   0.0  134  245-381    13-150 (167)
 84 4E4V_A Importin subunit alpha-  97.5   5E-08 5.7E-12   99.9   0.0  156  546-714   206-363 (485)
 85 1WA5_B GTP-BINDING NUCLEAR PRO  97.5 5.1E-08 5.8E-12  102.1   0.0  368  242-716    84-460 (530)
 86 1EE4_A KARYOPHERIN ALPHA; ARM   97.5 5.1E-08   6E-12   96.6   0.0  115  245-360    87-201 (423)
 87 1EE4_B KARYOPHERIN ALPHA; ARM   97.5 5.1E-08   6E-12   96.6   0.0  115  245-360    87-201 (423)
 88 4I2Z_A Protein UNC-45, Heat sh  97.5 6.2E-08   6E-12  114.3   0.0  431  248-725   443-904 (961)
 89 5XZX_A Importin subunit alpha-  97.5 6.3E-08 7.4E-12   95.7   0.0  360  246-711    46-415 (416)
 90 5MFO_F YIIIM3AIII; Designed ar  97.5 6.9E-08 8.1E-12   85.3   0.0  134  246-380     5-140 (202)
 91 3SL9_E Catenin beta-1, B-cell   97.5 7.2E-08 8.3E-12   83.6   0.0  134  245-381    13-150 (167)
 92 3NOW_A SD10334p; Armadillo Rep  97.5 7.3E-08 8.5E-12  105.4   0.0  110  247-358     8-120 (810)
 93 5MFO_E YIIIM3AIII; Designed ar  97.4 7.9E-08 9.3E-12   84.9   0.0  134  246-380     5-140 (202)
 94 4XZR_B Heh1-NLS, Kap60; karyop  97.4 8.1E-08 9.6E-12   95.0   0.0  115  245-360    87-201 (423)
 95 3OPB_A SWI5-dependent HO expre  97.4 9.1E-08 9.6E-12  108.6   0.0  168  546-719   544-734 (778)
 96 4I2W_A Protein UNC-45, Heat sh  97.4   1E-07 9.8E-12  112.5   0.0  433  247-726   442-905 (961)
 97 3TT9_A Plakophilin-2; CELL ADH  97.4 9.1E-08   1E-11   88.5   0.0  221  245-487     8-232 (233)
 98 2Z6H_A Catenin beta-1; Beta-Ca  97.4 9.4E-08   1E-11  103.9   0.0  378  241-726    10-395 (644)
 99 4U2X_E eVP24, KPNA5C; eVP24, i  97.4 9.4E-08 1.1E-11   83.8   0.0  116  246-362     9-125 (175)
100 4RV1_D Engineered Protein OR49  97.4 9.1E-08 1.1E-11   94.3   0.0  363  246-715    45-411 (420)
101 4BQK_A IMPORTIN SUBUNIT ALPHA-  97.4 9.4E-08 1.1E-11   96.1   0.0  158  545-714   170-329 (456)
102 5TBK_C Importin subunit alpha-  97.4   1E-07 1.2E-11   99.7   0.0  160  544-715   196-357 (521)
103 5TBK_D Importin subunit alpha-  97.4   1E-07 1.2E-11   99.7   0.0  160  544-715   196-357 (521)
104 4U2X_F eVP24, KPNA5C; eVP24, i  97.4 1.2E-07 1.4E-11   83.0   0.0  116  246-362     9-125 (175)
105 4V3Q_A YIII_M4_AII; DE NOVO PR  97.4 1.2E-07 1.4E-11   87.0   0.0  113  247-360    10-122 (247)
106 3NMZ_A APC variant protein, Rh  97.3 1.5E-07 1.7E-11   97.0   0.0  136  245-380   243-389 (458)
107 3L6X_A Catenin delta-1, E-cadh  97.3 1.6E-07 1.7E-11  102.1   0.0  377  246-672    91-522 (584)
108 5MFI_B YIII(Dq.V2)4CqI, (KR)4;  97.3 1.5E-07 1.8E-11   85.8   0.0  113  246-359     5-117 (243)
109 5MFJ_B YIII(Dq.V2)4CqI, (KR)5;  97.3 1.5E-07 1.8E-11   85.8   0.0  113  246-359     5-117 (243)
110 5VOZ_P V-type proton ATPase ca  97.3 2.1E-07 2.1E-11  101.0   0.0  134  246-382   124-281 (478)
111 5D80_H V-type proton ATPase ca  97.3 2.1E-07 2.1E-11  101.0   0.0  134  246-382   124-281 (478)
112 1JDH_A BETA-CATENIN, hTcf-4; B  97.3 1.9E-07 2.2E-11   95.6   0.0  138  245-382   266-409 (529)
113 2Z6G_A B-catenin; Full-Length,  97.3 2.2E-07 2.3E-11  105.1   0.0  353  245-671   276-664 (780)
114 1HO8_A VACUOLAR ATP SYNTHASE S  97.3 2.5E-07 2.5E-11  100.5   0.0  135  245-382   125-283 (480)
115 6S9O_F designed Armadillo repe  97.2 2.9E-07 3.4E-11   88.3   0.0  135  246-381   173-309 (344)
116 1XM9_A plakophilin 1  Plakophi  97.2 3.2E-07 3.6E-11   93.1   0.0  114  246-361   332-451 (457)
117 1XQS_B HSPBP1 protein, Heat sh  97.2 3.3E-07 3.7E-11   87.9   0.0  134  246-380    66-203 (280)
118 5MFI_B YIII(Dq.V2)4CqI, (KR)4;  97.2 3.4E-07   4E-11   83.4   0.0  134  246-380    47-182 (243)
119 5MFJ_B YIII(Dq.V2)4CqI, (KR)5;  97.2 3.4E-07   4E-11   83.4   0.0  134  246-380    47-182 (243)
120 6SA6_A DARPin-Armadillo fusion  97.2 3.9E-07 4.4E-11   91.0   0.0  134  246-380   200-335 (397)
121 6SA8_A ring-like DARPin-Armadi  97.2   4E-07 4.5E-11   98.8   0.0  135  245-380   220-356 (671)
122 1XQR_A HspBP1 protein; armadil  97.1 4.4E-07 4.9E-11   88.9   0.0  134  246-380    82-219 (296)
123 4UAD_A Importin alpha import a  97.1 4.5E-07 5.3E-11   91.8   0.0  368  245-718    23-398 (479)
124 5MFD_C YIIIM''6AII, Capsid dec  97.1 6.1E-07 7.2E-11   84.8   0.0  114  246-360    89-202 (328)
125 6HB3_B Protein HGH1; solenoid   97.1   7E-07 7.2E-11   92.3   0.0  121  246-369    52-208 (369)
126 3OPB_A SWI5-dependent HO expre  97.1 7.2E-07 7.6E-11  100.9   0.0  156  546-711   605-776 (778)
127 4HXT_A De Novo Protein OR329;   97.0 7.7E-07 9.1E-11   80.9   0.0  113  247-360     4-116 (252)
128 3GQ2_A General vesicular trans  97.0 9.1E-07 9.4E-11   98.4   0.0  136  245-381    60-219 (651)
129 3GRL_A General vesicular trans  97.0 9.1E-07 9.4E-11   98.4   0.0  136  245-381    60-219 (651)
130 4HXT_A De Novo Protein OR329;   97.0 8.1E-07 9.6E-11   80.7   0.0  114  246-360    45-158 (252)
131 4PLS_B Arm00010; PEPTIDE BINDI  97.0 8.3E-07 9.9E-11   82.1   0.0  114  246-360    44-157 (281)
132 5IZA_A Adenomatous polyposis c  97.0 9.5E-07 1.1E-10   87.4   0.0  114  245-358   127-246 (354)
133 5IZ8_A Adenomatous polyposis c  97.0   1E-06 1.1E-10   87.2   0.0  113  246-358   128-246 (354)
134 6SA7_B DARPin-Armadillo fusion  97.0 1.1E-06 1.2E-10   90.6   0.0  135  246-381   342-478 (510)
135 4V3Q_A YIII_M4_AII; DE NOVO PR  97.0 1.1E-06 1.3E-10   80.3   0.0  135  245-380    92-228 (247)
136 5Z8H_A Adenomatous polyposis c  96.9 1.2E-06 1.4E-10   85.0   0.0  134  245-379   122-267 (339)
137 5AEI_B DESIGNED ARMADILLO REPE  96.9 1.4E-06 1.7E-10   80.6   0.0  112  246-358   173-284 (286)
138 5IZA_A Adenomatous polyposis c  96.9 1.5E-06 1.7E-10   85.8   0.0  124  258-381    97-225 (354)
139 5IZ8_A Adenomatous polyposis c  96.9 1.6E-06 1.8E-10   85.8   0.0  124  258-381    97-225 (354)
140 3NMZ_A APC variant protein, Rh  96.9 1.6E-06 1.8E-10   88.9   0.0  135  246-381   287-432 (458)
141 6SA7_B DARPin-Armadillo fusion  96.9 1.6E-06 1.9E-10   89.2   0.0  134  246-380   300-435 (510)
142 5TBK_C Importin subunit alpha-  96.9 1.7E-06 1.9E-10   90.0   0.0  367  246-718   115-491 (521)
143 5TBK_D Importin subunit alpha-  96.9 1.7E-06 1.9E-10   90.0   0.0  367  246-718   115-491 (521)
144 6HB1_A Protein HGH1; solenoid   96.9 1.8E-06 1.9E-10   89.0   0.0  169  547-723    51-256 (369)
145 6HB2_D Protein HGH1; solenoid   96.9 1.8E-06 1.9E-10   89.0   0.0  169  547-723    51-256 (369)
146 5MFD_C YIIIM''6AII, Capsid dec  96.8 1.8E-06 2.1E-10   81.5   0.0  114  246-360    47-160 (328)
147 6SA7_B DARPin-Armadillo fusion  96.8 1.8E-06 2.1E-10   88.8   0.0  115  246-361   384-498 (510)
148 6S9O_F designed Armadillo repe  96.8 2.5E-06 2.9E-10   81.5   0.0  115  245-360    46-160 (344)
149 1XM9_A plakophilin 1  Plakophi  96.8 2.5E-06 2.9E-10   86.1   0.0  167  543-716    82-316 (457)
150 4HXT_A De Novo Protein OR329;   96.8 2.5E-06 2.9E-10   77.3   0.0  114  246-360   129-242 (252)
151 6SA6_A DARPin-Armadillo fusion  96.7   3E-06 3.4E-10   84.2   0.0  132  248-380   160-293 (397)
152 3NMZ_A APC variant protein, Rh  96.7 3.3E-06 3.7E-10   86.5   0.0  135  246-380   190-340 (458)
153 6HB1_A Protein HGH1; solenoid   96.6 5.3E-06 5.5E-10   85.4   0.0   93  287-381     9-108 (369)
154 6HB2_D Protein HGH1; solenoid   96.6 5.3E-06 5.5E-10   85.4   0.0   93  287-381     9-108 (369)
155 2W3C_A GENERAL VESICULAR TRANS  96.6 5.7E-06 5.9E-10   90.0   0.0  135  246-381    71-213 (577)
156 4XZR_B Heh1-NLS, Kap60; karyop  96.6 5.2E-06 6.2E-10   81.4   0.0  114  246-360   172-285 (423)
157 3TT9_A Plakophilin-2; CELL ADH  96.6   6E-06 6.8E-10   75.6   0.0  136  246-382    53-206 (233)
158 6HB3_B Protein HGH1; solenoid   96.6 6.6E-06 6.8E-10   84.6   0.0   93  287-381     9-108 (369)
159 6SA8_A ring-like DARPin-Armadi  96.5 6.4E-06 7.1E-10   88.9   0.0  322  286-714   177-502 (671)
160 1EE4_A KARYOPHERIN ALPHA; ARM   96.5 6.8E-06 8.1E-10   80.5   0.0  114  246-360   214-327 (423)
161 1EE4_B KARYOPHERIN ALPHA; ARM   96.5 6.8E-06 8.1E-10   80.5   0.0  114  246-360   214-327 (423)
162 5KC2_B Phosphatidylinositol 3-  96.5 9.9E-06   1E-09   98.5   0.0  150  546-715   618-768 (1454)
163 4B18_A IMPORTIN SUBUNIT ALPHA-  96.4 8.9E-06   1E-09   80.7   0.0  366  245-716    61-443 (447)
164 1JDH_A BETA-CATENIN, hTcf-4; B  96.4   9E-06 1.1E-09   82.5   0.0  363  245-712   143-529 (529)
165 5MFI_B YIII(Dq.V2)4CqI, (KR)4;  96.4 9.2E-06 1.1E-09   73.3   0.0  135  245-380    88-224 (243)
166 5MFJ_B YIII(Dq.V2)4CqI, (KR)5;  96.4 9.2E-06 1.1E-09   73.3   0.0  135  245-380    88-224 (243)
167 4MFU_A Beta-catenin-like prote  96.4 1.1E-05 1.1E-09   87.3   0.0  182  539-725    60-261 (490)
168 5AEI_B DESIGNED ARMADILLO REPE  96.4   1E-05 1.2E-09   74.6   0.0  134  246-380    89-224 (286)
169 4PLS_B Arm00010; PEPTIDE BINDI  96.4 1.1E-05 1.3E-09   74.1   0.0  111  246-357   170-280 (281)
170 4HM9_A Beta-catenin-like prote  96.4 1.4E-05 1.3E-09   88.6   0.0  181  539-725   138-339 (568)
171 3L6X_A Catenin delta-1, E-cadh  96.4 1.3E-05 1.4E-09   86.3   0.0  135  246-381   236-406 (584)
172 4U5L_A deltaIBB-importin-alpha  96.4 1.2E-05 1.4E-09   78.7   0.0  134  246-380   223-359 (426)
173 2JDQ_A IMPORTIN ALPHA-1 SUBUNI  96.3 1.3E-05 1.5E-09   79.6   0.0  366  245-716    64-446 (450)
174 3GQ2_A General vesicular trans  96.3 1.5E-05 1.5E-09   88.2   0.0  169  543-721   204-403 (651)
175 3GRL_A General vesicular trans  96.3 1.5E-05 1.5E-09   88.2   0.0  169  543-721   204-403 (651)
176 3TT9_A Plakophilin-2; CELL ADH  96.3 1.5E-05 1.7E-09   72.9   0.0  113  246-360    95-230 (233)
177 5D5K_C Importin subunit alpha-  96.3 1.5E-05 1.8E-09   79.2   0.0  113  246-359   273-386 (466)
178 4UAF_B Importin alpha 1 import  96.3 1.6E-05 1.8E-09   79.1   0.0  113  246-359   273-386 (466)
179 2JDQ_A IMPORTIN ALPHA-1 SUBUNI  96.2 1.8E-05 2.2E-09   78.4   0.0  134  246-380   235-371 (450)
180 3IFQ_A plakoglobin, E-cadherin  96.2 1.8E-05 2.2E-09   80.6   0.0  367  245-716   145-534 (553)
181 4BQK_A IMPORTIN SUBUNIT ALPHA-  96.2 1.9E-05 2.2E-09   78.5   0.0  116  245-360   172-287 (456)
182 4U5L_A deltaIBB-importin-alpha  96.2 2.2E-05 2.6E-09   76.7   0.0  115  245-360   180-294 (426)
183 4BPL_A IMPORTIN SUBUNIT ALPHA-  96.2 2.3E-05 2.7E-09   77.8   0.0  135  245-379   170-306 (454)
184 4MZ6_E Deoxyuridine 5'-triphos  96.1 2.6E-05 3.1E-09   79.0   0.0  113  246-359   317-430 (509)
185 5UMZ_B Importin subunit alpha-  96.1 2.6E-05 3.1E-09   79.0   0.0  113  246-359   317-430 (509)
186 4E4V_A Importin subunit alpha-  96.1 2.7E-05 3.1E-09   78.7   0.0  113  246-359   292-405 (485)
187 3GQ2_A General vesicular trans  96.1 3.4E-05 3.5E-09   85.2   0.0  176  543-726    56-255 (651)
188 3GRL_A General vesicular trans  96.1 3.4E-05 3.5E-09   85.2   0.0  176  543-726    56-255 (651)
189 4V3Q_A YIII_M4_AII; DE NOVO PR  96.0 3.4E-05   4E-09   69.7   0.0  112  246-358   135-246 (247)
190 4TNM_A Importin-alpha3 / MOS6;  96.0 3.5E-05   4E-09   79.5   0.0  136  245-380   245-382 (531)
191 4GMO_A Putative uncharacterize  95.9 5.4E-05 5.2E-09   85.2   0.0   94  245-339    34-129 (684)
192 4PLS_B Arm00010; PEPTIDE BINDI  95.9 4.9E-05 5.8E-09   69.4   0.0  134  246-380    86-221 (281)
193 5MFO_F YIIIM3AIII; Designed ar  95.9   5E-05 5.9E-09   65.8   0.0  112  246-358    89-200 (202)
194 2RU4_A Armadillo Repeat Protei  95.9 5.2E-05   6E-09   59.8   0.0  110  248-358     4-113 (115)
195 5AEI_B DESIGNED ARMADILLO REPE  95.9 5.1E-05 6.1E-09   69.5   0.0  114  246-360    47-160 (286)
196 5MFD_C YIIIM''6AII, Capsid dec  95.9 5.1E-05 6.1E-09   70.8   0.0  157  545-714   128-286 (328)
197 5MFO_E YIIIM3AIII; Designed ar  95.9 5.2E-05 6.2E-09   65.7   0.0  112  246-358    89-200 (202)
198 5D5K_C Importin subunit alpha-  95.8 5.5E-05 6.5E-09   74.9   0.0  158  544-714   138-302 (466)
199 1XQS_B HSPBP1 protein, Heat sh  95.8 5.9E-05 6.6E-09   71.4   0.0  116  246-362   109-225 (280)
200 4UAF_B Importin alpha 1 import  95.8 5.9E-05   7E-09   74.7   0.0  158  544-714   138-302 (466)
201 1XQR_A HspBP1 protein; armadil  95.8 6.4E-05   7E-09   72.7   0.0  116  246-362   125-241 (296)
202 6CRI_R Bone marrow stromal ant  95.8 6.2E-05 7.1E-09   78.2   0.0  151  547-721   414-577 (585)
203 6SA8_A ring-like DARPin-Armadi  95.8 6.8E-05 7.7E-09   80.4   0.0  136  245-381   262-399 (671)
204 5WBJ_A Regulatory-associated p  95.8 8.1E-05 7.9E-09   89.5   0.0  168  541-715   500-672 (1287)
205 5Z8H_A Adenomatous polyposis c  95.7 7.4E-05 8.5E-09   71.6   0.0  115  246-361   210-331 (339)
206 5WBK_A Regulatory-associated p  95.7 9.2E-05   9E-09   89.0   0.0  168  541-715   500-672 (1287)
207 6SA6_A DARPin-Armadillo fusion  95.7 8.4E-05 9.6E-09   73.2   0.0  135  245-380   241-377 (397)
208 2W3C_A GENERAL VESICULAR TRANS  95.6 0.00012 1.2E-08   79.1   0.0  136  246-382     9-168 (577)
209 6CRI_I Bone marrow stromal ant  95.6  0.0001 1.2E-08   74.8   0.0  106  244-360    72-177 (570)
210 1QBK_B STRUCTURE OF THE KARYOP  95.6 0.00011 1.3E-08   79.3   0.0  157  547-715   667-824 (890)
211 4P6Z_G BST2/tetherin, HIV-1 Vp  95.6 0.00012 1.3E-08   77.7   0.0  151  547-721   431-594 (627)
212 5MFI_B YIII(Dq.V2)4CqI, (KR)4;  95.5 0.00014 1.6E-08   65.0   0.0  112  246-358   131-242 (243)
213 5MFJ_B YIII(Dq.V2)4CqI, (KR)5;  95.5 0.00014 1.6E-08   65.0   0.0  112  246-358   131-242 (243)
214 5EWP_B Uncharacterized protein  95.4 0.00015 1.7E-08   67.3   0.0  134  246-380    87-233 (252)
215 4V3Q_A YIII_M4_AII; DE NOVO PR  95.4 0.00017   2E-08   64.8   0.0  134  246-380    51-186 (247)
216 3GQ2_A General vesicular trans  95.3 0.00022 2.3E-08   78.3   0.0  135  246-381   123-265 (651)
217 3GRL_A General vesicular trans  95.3 0.00022 2.3E-08   78.3   0.0  135  246-381   123-265 (651)
218 5AFF_A SYMPORTIN 1, RIBOSOMAL   95.2 0.00026 2.6E-08   78.8   0.0   94  245-339    12-107 (654)
219 6QH5_B AP-2 complex subunit al  95.2 0.00023 2.7E-08   73.0   0.0  107  243-360    84-190 (592)
220 3C2G_A Sys-1 protein, Pop-1 8-  95.2 0.00033 2.8E-08   77.7   0.0  189  260-486   185-412 (619)
221 4FDD_A Transportin-1, RNA-bind  95.1 0.00028 3.3E-08   75.3   0.0  157  547-715   629-786 (852)
222 4P6Z_B BST2/tetherin, HIV-1 Vp  95.0 0.00031 3.6E-08   72.5   0.0  106  244-360   101-206 (600)
223 2JKT_A AP-2 COMPLEX SUBUNIT AL  95.0 0.00032 3.7E-08   73.5   0.0  144  547-714   441-590 (623)
224 5IZ8_A Adenomatous polyposis c  95.0 0.00036 4.1E-08   67.8   0.0  162  543-716   166-337 (354)
225 5IZA_A Adenomatous polyposis c  94.9 0.00036 4.1E-08   67.8   0.0  162  543-716   166-337 (354)
226 5YVI_A Transportin-1, RNA-bind  94.9 0.00036 4.3E-08   74.5   0.0  156  547-714   645-801 (868)
227 6QH7_A AP-2 complex subunit al  94.9 0.00038 4.3E-08   73.0   0.0  108  242-360   108-217 (621)
228 1B3U_A PROTEIN PHOSPHATASE PP2  94.9  0.0004 4.8E-08   70.1   0.0  146  547-712   441-586 (588)
229 4HM9_A Beta-catenin-like prote  94.8 0.00057 5.4E-08   75.0   0.0  161  543-716   241-424 (568)
230 6QH5_A AP-2 complex subunit al  94.8 0.00048 5.5E-08   72.2   0.0  144  548-715   442-591 (621)
231 5MFO_F YIIIM3AIII; Designed ar  94.7 0.00052 6.2E-08   58.9   0.0  134  246-380    47-182 (202)
232 5MFO_E YIIIM3AIII; Designed ar  94.7 0.00054 6.3E-08   58.8   0.0  134  246-380    47-182 (202)
233 4MFU_A Beta-catenin-like prote  94.6 0.00067 6.6E-08   72.8   0.0  161  543-716   163-346 (490)
234 2NYL_A Protein phosphatase 2,   94.6 0.00059 7.1E-08   68.5   0.0  145  548-712   436-580 (582)
235 4U2X_F eVP24, KPNA5C; eVP24, i  94.4 0.00082 9.5E-08   57.1   0.0   73  246-318    51-124 (175)
236 3SL9_B Catenin beta-1, B-cell   94.3 0.00082 9.5E-08   56.5   0.0  110  246-357    56-166 (167)
237 4I5L_D PP2A A alpha subunit (9  94.3  0.0008 9.6E-08   67.6   0.0  110  246-359   239-349 (584)
238 4U2X_E eVP24, KPNA5C; eVP24, i  94.3 0.00091   1E-07   56.8   0.0   73  246-318    51-124 (175)
239 4UQI_B AP-2 COMPLEX SUBUNIT AL  94.2 0.00095 1.1E-07   70.3   0.0  106  244-360    85-190 (657)
240 5KC2_B Phosphatidylinositol 3-  94.0  0.0013 1.4E-07   79.1   0.0  155  544-715   506-689 (1454)
241 3SL9_E Catenin beta-1, B-cell   94.0  0.0012 1.4E-07   55.4   0.0  110  246-357    56-166 (167)
242 3VWA_B Cytoplasmic export prot  93.8  0.0017 1.8E-07   68.9   0.0  150  546-714   379-529 (560)
243 5DFZ_B Vacuolar protein sortin  93.7  0.0018 1.8E-07   77.7   0.0  155  546-719   608-762 (1460)
244 6HWP_A A3_bGFPD; alphaRep, art  93.7  0.0016 1.9E-07   62.8   0.0   91  245-358    23-113 (409)
245 3TT9_A Plakophilin-2; CELL ADH  93.7  0.0017 1.9E-07   58.2   0.0  169  542-716    47-232 (233)
246 3VWA_A Cytoplasmic export prot  93.6  0.0019   2E-07   68.6   0.0  152  545-715   378-530 (560)
247 1XQR_A HspBP1 protein; armadil  93.6  0.0019 2.1E-07   61.7   0.0  122  257-380    52-177 (296)
248 1XQS_B HSPBP1 protein, Heat sh  93.4  0.0023 2.6E-07   59.7   0.0  123  257-380    36-161 (280)
249 5VOZ_P V-type proton ATPase ca  93.3  0.0027 2.7E-07   67.5   0.0  330  290-714    78-475 (478)
250 5D80_H V-type proton ATPase ca  93.3  0.0027 2.7E-07   67.5   0.0  330  290-714    78-475 (478)
251 1F59_B IMPORTIN BETA-1/FXFG NU  93.3  0.0024 2.8E-07   62.2   0.0  154  549-713   261-437 (442)
252 6XTE_A Importin-5, antipain; h  93.2  0.0025 2.9E-07   70.4   0.0  153  548-714   358-521 (1096)
253 4HXT_A De Novo Protein OR329;   93.2  0.0025   3E-07   56.2   0.0  134  246-380    87-222 (252)
254 5IFE_C Splicing factor 3B subu  93.2  0.0029   3E-07   75.0   0.0  153  548-714   932-1087(1304)
255 6AHD_1 Pre-mRNA-processing-spl  93.2  0.0029   3E-07   75.0   0.0  153  548-714   932-1087(1304)
256 6QH5_B AP-2 complex subunit al  93.1  0.0027 3.1E-07   64.6   0.0  146  548-714   428-573 (592)
257 6EN4_C Splicing factor 3B subu  92.9  0.0031 3.6E-07   67.4   0.0  154  548-714   480-635 (852)
258 6SA6_A DARPin-Armadillo fusion  92.9  0.0032 3.7E-07   61.0   0.0  112  246-358   284-395 (397)
259 6FT5_A A3_A3; alphaRep, artifi  92.9  0.0032 3.7E-07   60.7   0.0   91  245-358    23-113 (409)
260 3C5W_A PP2A A subunit, PP2A C;  92.9  0.0032 3.8E-07   54.7   0.0  146  548-713    86-231 (232)
261 4LAC_A Serine/threonine-protei  92.9  0.0033 3.8E-07   56.3   0.0  110  545-670    31-140 (258)
262 4FDD_A Transportin-1, RNA-bind  92.6  0.0039 4.6E-07   65.8   0.0  150  548-712   360-511 (852)
263 5NR4_A CLIP-associating protei  92.6   0.004 4.6E-07   54.4   0.0  148  548-715    53-200 (230)
264 3C5W_A PP2A A subunit, PP2A C;  92.5  0.0041 4.8E-07   53.9   0.0  107  548-670     8-114 (232)
265 6XU2_A Importin-5, antipain; h  92.5  0.0042 4.9E-07   68.8   0.0  152  548-713   377-539 (1115)
266 4LAC_A Serine/threonine-protei  92.5  0.0043   5E-07   55.5   0.0  146  548-713   112-257 (258)
267 6EN4_C Splicing factor 3B subu  92.5  0.0043   5E-07   66.2   0.0  147  547-714   675-823 (852)
268 1QBK_B STRUCTURE OF THE KARYOP  92.4  0.0043 5.1E-07   66.1   0.0  151  548-713   398-550 (890)
269 6CRI_I Bone marrow stromal ant  92.4  0.0043 5.1E-07   62.1   0.0  145  548-714   415-560 (570)
270 2RU4_B Armadillo Repeat Protei  92.4  0.0045 5.2E-07   45.3   0.0   71  287-358    12-82  (84)
271 4L7M_A Putative uncharacterize  92.3  0.0047 5.5E-07   55.6   0.0   75  545-625    35-109 (269)
272 5WBJ_A Regulatory-associated p  92.2  0.0059 5.8E-07   72.7   0.0  100  561-671   612-725 (1287)
273 5WBK_A Regulatory-associated p  92.2  0.0059 5.8E-07   72.7   0.0  101  560-671   611-725 (1287)
274 2QK2_A LP04448p; Mini spindles  92.2   0.005 5.8E-07   54.5   0.0  145  548-714    16-163 (242)
275 3W3U_A Importin subunit beta-3  92.2   0.005 5.8E-07   67.5   0.0  115  245-360   397-512 (1078)
276 2IW3_B ELONGATION FACTOR 3A; A  92.0  0.0058 6.5E-07   68.1   0.0  148  548-713   176-324 (986)
277 4G3A_B CLIP-associating protei  91.9  0.0059 6.8E-07   54.0   0.0  150  547-714     7-158 (237)
278 5EWP_B Uncharacterized protein  91.9  0.0062 6.9E-07   55.7   0.0  176  528-716     7-209 (252)
279 4QMI_B Cytoskeleton-associated  91.9   0.006 6.9E-07   54.1   0.0  147  548-715    60-208 (240)
280 4QMJ_A Cytoskeleton-associated  91.9   0.006 6.9E-07   54.1   0.0  147  548-715    60-208 (240)
281 5XAH_A Importin-4; Histone, Ch  91.8  0.0062 7.2E-07   58.5   0.0  153  548-714   235-389 (416)
282 5XAH_C Importin-4; Histone, Ch  91.8  0.0062 7.2E-07   58.5   0.0  153  548-714   235-389 (416)
283 2QK1_A Protein STU2; stu2, Stu  91.8  0.0063 7.3E-07   53.8   0.0  152  548-714    17-176 (249)
284 5H2V_A Importin subunit beta-3  91.8  0.0063 7.4E-07   66.7   0.0  114  246-360   398-512 (1078)
285 6OWT_A AP-2 complex subunit al  91.7  0.0072 7.8E-07   67.7   0.0  142  548-713   442-589 (939)
286 2P8Q_A Importin beta-1 subunit  91.7  0.0066 7.8E-07   64.5   0.0  160  548-715   650-829 (876)
287 5MFO_F YIIIM3AIII; Designed ar  91.6  0.0068   8E-07   51.3   0.0  157  546-715     3-161 (202)
288 5MFO_E YIIIM3AIII; Designed ar  91.6   0.007 8.3E-07   51.2   0.0  157  546-715     3-161 (202)
289 2QNA_A Importin subunit beta-1  91.5  0.0073 8.6E-07   62.8   0.0  159  548-714   525-703 (762)
290 6G4J_B Probable serine/threoni  91.5   0.008 8.8E-07   50.6   0.0  132  548-723    15-146 (148)
291 3W3W_A Importin subunit beta-3  91.3  0.0081 9.5E-07   65.7   0.0   98  609-715   821-920 (1078)
292 3ND2_A Importin subunit beta-1  91.2  0.0083 9.8E-07   63.2   0.0  152  548-713   598-763 (861)
293 5OWU_A Importin subunit beta-1  91.2  0.0083 9.8E-07   63.2   0.0  152  548-713   598-763 (861)
294 5DFZ_B Vacuolar protein sortin  91.0   0.011 1.1E-06   70.6   0.0  159  546-714   463-639 (1460)
295 3W3U_A Importin subunit beta-3  90.7   0.011 1.3E-06   64.7   0.0  157  548-713   440-600 (1078)
296 1QGR_A IMPORTIN BETA SUBUNIT,   90.6   0.011 1.3E-06   62.8   0.0  113  246-360   367-480 (876)
297 4QMH_A LP04448p; PROTEIN BINDI  90.4   0.012 1.4E-06   51.8   0.0  149  548-715    58-209 (241)
298 5A1V_E ADP-RIBOSYLATION FACTOR  90.4   0.013 1.4E-06   64.9   0.0  102  244-359    67-168 (874)
299 5NZR_G Coatomer subunit alpha,  90.4   0.013 1.4E-06   64.9   0.0  102  244-359    67-168 (874)
300 3W3W_A Importin subunit beta-3  90.3   0.013 1.5E-06   64.1   0.0  157  547-714   439-601 (1078)
301 5H2V_A Importin subunit beta-3  90.2   0.013 1.5E-06   64.0   0.0  158  547-714   439-601 (1078)
302 4NEE_G AP-2 complex subunit si  90.1   0.014 1.6E-06   56.7   0.0  141  548-714    77-219 (398)
303 6MQ5_A CLIP-associating protei  90.0   0.015 1.7E-06   52.9   0.0  111  548-670     4-120 (257)
304 4UQI_B AP-2 COMPLEX SUBUNIT AL  90.0   0.015 1.7E-06   60.6   0.0  109  245-359   160-268 (657)
305 4XRI_A Importin Beta; Transpor  89.9   0.014 1.7E-06   61.5   0.0  159  548-715   651-826 (882)
306 4NEE_B AP-2 complex subunit si  89.8   0.016 1.8E-06   56.6   0.0  141  548-714    77-219 (398)
307 6EN4_C Splicing factor 3B subu  89.8   0.015 1.8E-06   61.6   0.0  153  548-714   397-551 (852)
308 5A1V_E ADP-RIBOSYLATION FACTOR  89.6   0.018 1.9E-06   63.8   0.0  141  548-714   397-538 (874)
309 5NZR_G Coatomer subunit alpha,  89.6   0.018 1.9E-06   63.8   0.0  141  548-714   397-538 (874)
310 6OWT_A AP-2 complex subunit al  89.5   0.018   2E-06   64.2   0.0   98  250-360    79-178 (939)
311 5KC2_B Phosphatidylinositol 3-  89.3   0.021 2.1E-06   68.3   0.0  151  548-714   424-610 (1454)
312 2P8Q_A Importin beta-1 subunit  89.3   0.018 2.1E-06   60.9   0.0  154  548-714   367-538 (876)
313 2QNA_A Importin subunit beta-1  89.1   0.019 2.3E-06   59.4   0.0  115  245-360     3-122 (762)
314 1IBR_B RAN  IMPORTIN BETA SUBU  89.1   0.019 2.3E-06   55.6   0.0  154  548-714   129-289 (462)
315 1QGR_A IMPORTIN BETA SUBUNIT,   88.9   0.021 2.4E-06   60.6   0.0  154  548-714   367-538 (876)
316 2DB0_A 253aa long hypothetical  88.9   0.021 2.4E-06   50.5   0.0  141  548-715   108-248 (253)
317 2DB0_B 253aa long hypothetical  88.9   0.021 2.4E-06   50.5   0.0  141  548-715   108-248 (253)
318 4K92_B CLIP-associating protei  88.8   0.022 2.5E-06   52.5   0.0  148  548-714    90-237 (273)
319 6MQ7_B CLIP-associating protei  88.8   0.022 2.5E-06   52.5   0.0  148  548-714    90-237 (273)
320 1GCJ_B IMPORTIN-BETA; HEAT REP  88.7   0.022 2.5E-06   55.4   0.0  154  548-714   135-295 (460)
321 1F59_B IMPORTIN BETA-1/FXFG NU  88.7   0.022 2.6E-06   54.8   0.0  154  548-714   129-289 (442)
322 1UKL_A Importin beta-1 subunit  88.6   0.022 2.6E-06   60.2   0.0  113  246-360   367-480 (876)
323 1U6G_C Cullin homolog 1, RING-  88.2   0.025 2.9E-06   62.9   0.0  146  548-714   891-1036(1230)
324 4MFU_A Beta-catenin-like prote  88.1   0.031 3.1E-06   59.1   0.0  135  246-381    69-222 (490)
325 6CRI_I Bone marrow stromal ant  87.6    0.03 3.5E-06   55.5   0.0  141  548-714    37-177 (570)
326 3QML_D 78 kDa glucose-regulate  87.5   0.038 3.6E-06   55.4   0.0  165  534-712    56-246 (315)
327 5IFE_C Splicing factor 3B subu  87.4   0.036 3.7E-06   65.2   0.0  154  547-714   848-1003(1304)
328 6AHD_1 Pre-mRNA-processing-spl  87.4   0.036 3.7E-06   65.2   0.0  154  547-714   848-1003(1304)
329 5MU7_A Coatomer subunit beta,   87.4   0.031 3.7E-06   52.4   0.0  141  549-716   190-331 (373)
330 5VE8_B Kap123, Histone H3; Bid  87.4   0.031 3.7E-06   61.1   0.0  154  549-714   868-1034(1116)
331 2IX8_A ELONGATION FACTOR 3A; N  87.3   0.034 3.8E-06   61.3   0.0  150  547-713    48-198 (976)
332 3WOY_A CLIP-associating protei  87.3   0.034 3.8E-06   50.1   0.0  147  548-714    78-225 (251)
333 5DN7_A Protein FAM179B; TOG do  87.2   0.035 3.9E-06   52.0   0.0  146  548-714    67-212 (293)
334 4HM9_A Beta-catenin-like prote  87.2    0.04 3.9E-06   59.6   0.0  135  246-381   147-300 (568)
335 6S47_Bi 60S ribosomal protein   87.2   0.035 3.9E-06   61.2   0.0  155  546-713    42-198 (972)
336 6QH5_B AP-2 complex subunit al  87.1   0.034   4E-06   55.8   0.0  142  548-715    50-191 (592)
337 5A1V_G ADP-RIBOSYLATION FACTOR  87.1   0.037   4E-06   61.9   0.0  105  547-670   259-364 (968)
338 3TJZ_B ADP-ribosylation factor  87.0   0.036 4.1E-06   52.5   0.0   16  697-712   225-240 (355)
339 2IW3_B ELONGATION FACTOR 3A; A  86.9   0.037 4.1E-06   61.1   0.0  151  547-714    54-205 (986)
340 5NZR_B Coatomer subunit alpha,  86.8    0.04 4.3E-06   61.6   0.0  105  547-670   259-364 (968)
341 4P6Z_B BST2/tetherin, HIV-1 Vp  86.8   0.037 4.3E-06   55.9   0.0  142  548-715    66-207 (600)
342 5VCH_A Kap123; Bidding yeast k  86.7   0.038 4.4E-06   60.5   0.0  153  550-714   869-1034(1116)
343 6BCU_A mTOR, Target of rapamyc  86.7    0.04 4.4E-06   67.9   0.0  131  549-694   952-1084(2549)
344 6BCX_B mTOR, Target of rapamyc  86.7    0.04 4.4E-06   67.9   0.0  131  549-694   952-1084(2549)
345 5IFE_C Splicing factor 3B subu  86.4   0.045 4.7E-06   64.2   0.0  110  249-359   935-1044(1304)
346 6AHD_1 Pre-mRNA-processing-spl  86.4   0.045 4.7E-06   64.2   0.0  110  249-359   935-1044(1304)
347 6LTJ_L Histone H3.2, Histone H  86.4   0.056 4.7E-06   63.5   0.0  152  563-723  1065-1263(1295)
348 6CRI_R Bone marrow stromal ant  86.2   0.043 4.9E-06   55.5   0.0  139  548-714    63-201 (585)
349 5DFZ_B Vacuolar protein sortin  85.9   0.051 5.3E-06   64.4   0.0  292  245-645   464-781 (1460)
350 2QNA_A Importin subunit beta-1  85.8   0.046 5.4E-06   56.3   0.0  154  548-714     4-164 (762)
351 3WOZ_C CLIP-associating protei  85.7   0.049 5.4E-06   48.6   0.0  154  547-716     5-159 (232)
352 3WOZ_D CLIP-associating protei  85.7   0.049 5.4E-06   48.6   0.0  154  547-716     5-159 (232)
353 5DCQ_C artificial repeat prote  85.5   0.051 5.7E-06   45.4   0.0   47  654-712   120-166 (170)
354 4L7M_A Putative uncharacterize  85.3   0.051   6E-06   48.1   0.0  143  548-713   120-265 (269)
355 4P6Z_B BST2/tetherin, HIV-1 Vp  85.1   0.053 6.2E-06   54.6   0.0  109  245-359   176-284 (600)
356 5MU7_A Coatomer subunit beta,   85.1   0.053 6.2E-06   50.7   0.0  101  598-714   191-292 (373)
357 4UQI_B AP-2 COMPLEX SUBUNIT AL  85.0   0.056 6.3E-06   55.9   0.0  142  548-715    50-191 (657)
358 6MZE_Z Tubulin alpha-1A chain,  84.9   0.055 6.4E-06   53.4   0.0  149  548-715   340-496 (536)
359 4MFU_A Beta-catenin-like prote  84.8   0.067 6.5E-06   56.4   0.0  117  610-733    42-175 (490)
360 5N3U_B Phycocyanobilin lyase s  84.6    0.06 6.9E-06   46.1   0.0  135  547-714    32-167 (208)
361 6QH5_B AP-2 complex subunit al  84.4    0.06   7E-06   53.8   0.0  145  548-713   122-268 (592)
362 2DB0_A 253aa long hypothetical  84.4   0.062 7.1E-06   47.2   0.0  104  547-670    32-136 (253)
363 2DB0_B 253aa long hypothetical  84.4   0.062 7.1E-06   47.2   0.0  104  547-670    32-136 (253)
364 2JKT_A AP-2 COMPLEX SUBUNIT AL  84.2   0.064 7.3E-06   54.8   0.0  140  548-713    75-216 (623)
365 3LTJ_A AlphaRep-4; protein eng  84.1   0.065 7.5E-06   45.7   0.0   28  685-713   140-167 (201)
366 4P6Z_B BST2/tetherin, HIV-1 Vp  84.1   0.065 7.5E-06   54.0   0.0  145  548-713   138-284 (600)
367 6QH7_A AP-2 complex subunit al  84.0   0.067 7.6E-06   54.8   0.0  140  548-713    75-216 (621)
368 6CRI_R Bone marrow stromal ant  83.9   0.067 7.7E-06   53.9   0.0   67  548-625   135-201 (585)
369 4UQI_B AP-2 COMPLEX SUBUNIT AL  83.9   0.069 7.8E-06   55.2   0.0  145  548-713   122-268 (657)
370 5XAH_A Importin-4; Histone, Ch  83.5   0.071 8.2E-06   50.5   0.0  142  561-715   163-307 (416)
371 5XAH_C Importin-4; Histone, Ch  83.5   0.071 8.2E-06   50.5   0.0  142  561-715   163-307 (416)
372 5FRS_A SISTER CHROMATID COHESI  83.5    0.08 8.3E-06   57.5   0.0  149  548-715   282-431 (703)
373 4HM9_A Beta-catenin-like prote  83.5   0.087 8.3E-06   56.8   0.0  136  246-381   198-350 (568)
374 5FRP_A SISTER CHROMATID COHESI  83.4   0.082 8.4E-06   57.5   0.0  149  548-715   282-431 (703)
375 5GM6_G Prp8, Brr2, Snu114, Rse  83.4   0.077 8.4E-06   58.7   0.0   69  248-316   603-671 (971)
376 5ZWM_1 Pre-mRNA-splicing facto  83.4   0.077 8.4E-06   58.7   0.0   69  248-316   603-671 (971)
377 3TJZ_B ADP-ribosylation factor  83.4   0.075 8.5E-06   50.1   0.0  102  596-712   251-352 (355)
378 6CRI_R Bone marrow stromal ant  83.3   0.075 8.6E-06   53.5   0.0  101  246-359   100-200 (585)
379 6U62_A Regulatory-associated p  83.0   0.095   9E-06   62.5   0.0  159  544-715   468-630 (1392)
380 6BCX_W mTOR, Target of rapamyc  82.8   0.098 9.3E-06   62.1   0.0  159  544-715   476-638 (1343)
381 4QMH_A LP04448p; PROTEIN BINDI  82.8   0.081 9.4E-06   46.0   0.0  114  595-716    17-130 (241)
382 6QH5_A AP-2 complex subunit al  82.8   0.083 9.4E-06   54.0   0.0  140  548-713    75-216 (621)
383 6EMK_C Serine/threonine-protei  82.8   0.086 9.4E-06   64.9   0.0   71  548-625   922-993 (2474)
384 5MU7_A Coatomer subunit beta,   82.7   0.082 9.5E-06   49.3   0.0   71  548-624    39-110 (373)
385 6CRI_I Bone marrow stromal ant  82.7   0.081 9.6E-06   52.1   0.0  145  548-713   109-255 (570)
386 4QMI_B Cytoskeleton-associated  82.6   0.084 9.7E-06   46.0   0.0  112  595-715    19-131 (240)
387 4QMJ_A Cytoskeleton-associated  82.6   0.084 9.7E-06   46.0   0.0  112  595-715    19-131 (240)
388 6MZG_E Tubulin alpha-1A chain,  82.5   0.084 9.8E-06   52.4   0.0  147  549-715   315-466 (554)
389 1B3U_A PROTEIN PHOSPHATASE PP2  82.3   0.085   1E-05   51.8   0.0  147  547-713   164-310 (588)
390 2OF3_A ZYG-9; Multifunctional   82.0   0.098 1.1E-05   48.1   0.0  150  548-714    88-237 (266)
391 4I5L_D PP2A A alpha subunit (9  81.8   0.092 1.1E-05   51.5   0.0  147  547-713   160-306 (584)
392 4Y5J_A Mini spindles TOG3; XMA  81.7   0.097 1.1E-05   46.2   0.0   71  548-625    15-89  (248)
393 4P6Z_G BST2/tetherin, HIV-1 Vp  81.6     0.1 1.1E-05   53.7   0.0  137  549-713    81-217 (627)
394 5KC2_B Phosphatidylinositol 3-  81.5    0.11 1.2E-05   61.5   0.0  126  247-379   621-746 (1454)
395 6MZG_E Tubulin alpha-1A chain,  81.1     0.1 1.2E-05   51.7   0.0  151  550-714    57-211 (554)
396 6MZE_Z Tubulin alpha-1A chain,  81.1     0.1 1.2E-05   51.2   0.0  108  600-714   300-412 (536)
397 6RXU_UJ Periodic tryptophan pr  80.9    0.12 1.2E-05   62.5   0.0  152  548-713  1625-1791(1802)
398 5FVM_B SERINE/THREONINE-PROTEI  80.8    0.12 1.3E-05   63.5   0.0  147  548-714  1008-1155(2471)
399 6GWC_C Tubulin alpha chain, Tu  80.7    0.11 1.3E-05   45.3   0.0   49  654-714   120-168 (232)
400 1OYZ_A X-RAY STRUCTURE OF YB61  80.6    0.11 1.3E-05   46.1   0.0   64  549-623    92-156 (280)
401 6GX7_F Tubulin alpha chain, Tu  80.5    0.12 1.3E-05   44.1   0.0  122  548-713    46-167 (201)
402 2NYL_A Protein phosphatase 2,   80.4    0.11 1.3E-05   50.7   0.0  147  547-713   158-304 (582)
403 5VJC_B Protein mini spindles;   80.3    0.12 1.4E-05   47.2   0.0   72  547-625    50-121 (271)
404 6RXV_UJ Periodic tryptophan pr  80.3    0.13 1.4E-05   62.1   0.0  152  548-713  1625-1791(1802)
405 4I5L_D PP2A A alpha subunit (9  80.2    0.11 1.4E-05   50.8   0.0  109  547-670   238-349 (584)
406 1IBR_B RAN  IMPORTIN BETA SUBU  80.2    0.12 1.4E-05   49.6   0.0  156  549-716   261-440 (462)
407 1B3U_A PROTEIN PHOSPHATASE PP2  80.1    0.12 1.4E-05   50.8   0.0  109  547-670   242-353 (588)
408 4P6Z_G BST2/tetherin, HIV-1 Vp  80.0    0.13 1.4E-05   52.9   0.0   67  548-625   152-218 (627)
409 5NR4_A CLIP-associating protei  80.0    0.12 1.4E-05   44.1   0.0  109  244-360    51-159 (230)
410 2P8Q_A Importin beta-1 subunit  79.9    0.12 1.4E-05   54.0   0.0  154  548-714   129-289 (876)
411 4I5L_D PP2A A alpha subunit (9  79.9    0.12 1.4E-05   50.6   0.0  147  547-713   320-466 (584)
412 1QGR_A IMPORTIN BETA SUBUNIT,   79.8    0.12 1.4E-05   54.2   0.0  154  548-714   129-289 (876)
413 1B3U_A PROTEIN PHOSPHATASE PP2  79.8    0.12 1.5E-05   50.6   0.0  146  547-712   324-469 (588)
414 6MZE_Z Tubulin alpha-1A chain,  79.7    0.13 1.5E-05   50.5   0.0  152  550-715    57-212 (536)
415 5F0N_A cohesin subunit Pds5, K  79.1    0.17 1.6E-05   59.2   0.0  150  547-714   271-420 (1175)
416 4NEE_G AP-2 complex subunit si  78.8    0.15 1.7E-05   48.9   0.0  115  548-671   149-273 (398)
417 3W3U_A Importin subunit beta-3  78.8    0.14 1.7E-05   55.2   0.0  158  548-714   849-1007(1078)
418 4NEE_B AP-2 complex subunit si  78.7    0.15 1.7E-05   49.0   0.0  115  548-671   149-273 (398)
419 3DAD_A FH1/FH2 domain-containi  78.5    0.18 1.7E-05   50.5   0.0  154  565-729   135-309 (339)
420 5VJC_A Protein mini spindles;   78.4    0.16 1.7E-05   46.5   0.0   73  546-625    49-121 (271)
421 5WBJ_A Regulatory-associated p  78.3    0.18 1.8E-05   59.3   0.0  156  548-716   467-631 (1287)
422 5WBK_A Regulatory-associated p  78.3    0.18 1.8E-05   59.3   0.0  156  548-716   467-631 (1287)
423 6EN4_C Splicing factor 3B subu  78.2    0.15 1.8E-05   53.3   0.0  154  548-715   192-347 (852)
424 5F0O_A cohesin subunit Pds5, K  78.2    0.18 1.8E-05   58.5   0.0  150  547-714   280-429 (1133)
425 2NYL_A Protein phosphatase 2,   77.8    0.16 1.9E-05   49.5   0.0  109  547-670   236-347 (582)
426 3W3W_A Importin subunit beta-3  77.6    0.16 1.9E-05   54.7   0.0  157  548-714   849-1007(1078)
427 4LAC_A Serine/threonine-protei  77.5    0.17 1.9E-05   44.2   0.0  115  239-360    27-141 (258)
428 6FT5_A A3_A3; alphaRep, artifi  77.5    0.17 1.9E-05   47.7   0.0   60  547-623    54-113 (409)
429 1F59_B IMPORTIN BETA-1/FXFG NU  77.4    0.17   2E-05   48.1   0.0  158  547-714    35-204 (442)
430 2NYL_A Protein phosphatase 2,   77.3    0.16   2E-05   49.4   0.0   70  547-625   318-387 (582)
431 5FVM_B SERINE/THREONINE-PROTEI  77.2    0.18   2E-05   61.6   0.0   71  548-625   925-996 (2471)
432 3LTJ_A AlphaRep-4; protein eng  77.2    0.18   2E-05   42.7   0.0  121  548-712    77-197 (201)
433 5JO8_A CEP104; centriolar prot  77.2    0.18   2E-05   46.5   0.0  155  548-714    87-245 (279)
434 4P6Z_G BST2/tetherin, HIV-1 Vp  77.2    0.18   2E-05   51.7   0.0  101  246-359   117-217 (627)
435 1GCJ_B IMPORTIN-BETA; HEAT REP  77.2    0.17   2E-05   48.4   0.0  154  549-714   267-444 (460)
436 6GWC_C Tubulin alpha chain, Tu  76.9    0.18 2.1E-05   43.9   0.0  121  548-712   108-228 (232)
437 3QML_D 78 kDa glucose-regulate  76.8    0.22 2.1E-05   49.4   0.0  104  609-717    42-154 (315)
438 4G3A_B CLIP-associating protei  76.8    0.18 2.1E-05   43.5   0.0  113  244-358     6-118 (237)
439 6IDX_A Engulfment and cell mot  76.8    0.22 2.1E-05   52.8   0.0  157  563-731   102-272 (524)
440 6IE1_A Engulfment and cell mot  76.8    0.22 2.1E-05   52.8   0.0  157  563-731   102-272 (524)
441 5H2V_A Importin subunit beta-3  76.6    0.18 2.1E-05   54.2   0.0  157  548-714   849-1007(1078)
442 1TE4_A conserved protein MTH18  76.5    0.19 2.2E-05   39.5   0.0  118  548-710    13-130 (131)
443 6S47_Bi 60S ribosomal protein   76.5     0.2 2.2E-05   54.8   0.0  155  548-714   127-321 (972)
444 1OYZ_A X-RAY STRUCTURE OF YB61  76.4    0.19 2.2E-05   44.5   0.0   96  596-712    91-187 (280)
445 5NR4_A CLIP-associating protei  76.2    0.19 2.2E-05   42.7   0.0  111  595-713     6-122 (230)
446 5A1V_E ADP-RIBOSYLATION FACTOR  75.9    0.22 2.3E-05   54.5   0.0  137  548-713    69-205 (874)
447 5NZR_G Coatomer subunit alpha,  75.9    0.22 2.3E-05   54.5   0.0  137  548-713    69-205 (874)
448 6HWP_A A3_bGFPD; alphaRep, art  75.5    0.21 2.4E-05   46.8   0.0   49  654-714   129-177 (409)
449 3W3U_A Importin subunit beta-3  75.5    0.21 2.4E-05   53.8   0.0  152  549-714   358-512 (1078)
450 4QMI_B Cytoskeleton-associated  75.5    0.21 2.4E-05   43.2   0.0  107  245-360    59-167 (240)
451 4QMJ_A Cytoskeleton-associated  75.5    0.21 2.4E-05   43.2   0.0  107  245-360    59-167 (240)
452 2IX8_A ELONGATION FACTOR 3A; N  75.4    0.22 2.4E-05   54.3   0.0  153  548-713   128-318 (976)
453 5XAH_A Importin-4; Histone, Ch  75.4    0.21 2.4E-05   46.9   0.0  162  548-713    33-222 (416)
454 5XAH_C Importin-4; Histone, Ch  75.4    0.21 2.4E-05   46.9   0.0  162  548-713    33-222 (416)
455 5H2V_A Importin subunit beta-3  75.1    0.22 2.5E-05   53.6   0.0  154  548-714   357-512 (1078)
456 6OWT_A AP-2 complex subunit al  75.0    0.24 2.6E-05   54.6   0.0  140  548-713    75-216 (939)
457 4G3A_B CLIP-associating protei  74.9    0.22 2.6E-05   42.9   0.0  107  548-671    91-198 (237)
458 4XL5_C Green fluorescent prote  74.6    0.23 2.7E-05   43.8   0.0  121  548-712   139-259 (263)
459 4FDD_A Transportin-1, RNA-bind  74.5    0.23 2.7E-05   51.3   0.0  155  548-714   129-286 (852)
460 4D4Z_A DEOXYHYPUSINE HYDROXYLA  74.4    0.23 2.7E-05   44.2   0.0  124  546-711     9-134 (294)
461 4D50_A DEOXYHYPUSINE HYDROXYLA  74.4    0.23 2.7E-05   44.2   0.0  124  546-711     9-134 (294)
462 6QH5_A AP-2 complex subunit al  74.2    0.24 2.8E-05   50.3   0.0   69  548-625   147-217 (621)
463 5LPH_B Centrosomal protein of   74.0    0.26 2.8E-05   45.9   0.0  155  549-714    94-251 (288)
464 1QBK_B STRUCTURE OF THE KARYOP  73.9    0.24 2.8E-05   51.6   0.0  156  548-715   129-287 (890)
465 3W3W_A Importin subunit beta-3  73.9    0.24 2.9E-05   53.2   0.0  153  548-714   357-512 (1078)
466 1IBR_B RAN  IMPORTIN BETA SUBU  73.6    0.25 2.9E-05   47.1   0.0  158  547-714    35-204 (462)
467 5VCH_A Kap123; Bidding yeast k  73.4    0.26   3E-05   53.4   0.0  153  548-714   361-516 (1116)
468 6QH7_A AP-2 complex subunit al  73.4    0.26   3E-05   50.0   0.0   69  548-625   147-217 (621)
469 2JKT_A AP-2 COMPLEX SUBUNIT AL  73.3    0.27   3E-05   49.9   0.0   69  548-625   147-217 (623)
470 1GCJ_B IMPORTIN-BETA; HEAT REP  73.0    0.27 3.1E-05   47.0   0.0  158  547-714    41-210 (460)
471 1OYZ_A X-RAY STRUCTURE OF YB61  73.0    0.27 3.1E-05   43.4   0.0  121  547-710   159-279 (280)
472 2JKT_A AP-2 COMPLEX SUBUNIT AL  72.8    0.28 3.2E-05   49.7   0.0   67  548-623   330-397 (623)
473 5VE8_B Kap123, Histone H3; Bid  72.7    0.27 3.2E-05   53.1   0.0  153  548-714   361-516 (1116)
474 4ZV6_A AlphaRep-7, Octarellin   71.7     0.3 3.5E-05   43.7   0.0   29  685-714   140-168 (294)
475 6BZX_A alpha-Rep, Octarellin V  71.4    0.31 3.6E-05   43.6   0.0   29  685-714   140-168 (294)
476 5IFE_C Splicing factor 3B subu  70.4    0.38 3.9E-05   55.8   0.0  154  548-715   644-799 (1304)
477 6AHD_1 Pre-mRNA-processing-spl  70.4    0.38 3.9E-05   55.8   0.0  154  548-715   644-799 (1304)
478 2QK2_A LP04448p; Mini spindles  70.3    0.34   4E-05   41.6   0.0  113  243-358    13-126 (242)
479 6MZG_E Tubulin alpha-1A chain,  70.0    0.35 4.1E-05   47.5   0.0   71  549-625   138-211 (554)
480 6QH7_A AP-2 complex subunit al  69.9    0.36 4.1E-05   48.9   0.0  100  247-359    76-177 (621)
481 1UKL_A Importin beta-1 subunit  69.9    0.35 4.1E-05   50.3   0.0  154  548-714   129-289 (876)
482 6EMK_C Serine/threonine-protei  69.9    0.38 4.1E-05   58.8   0.0  136  562-714  1016-1152(2474)
483 4XL5_C Green fluorescent prote  69.9    0.36 4.1E-05   42.4   0.0   49  654-714   120-168 (263)
484 4D4Z_A DEOXYHYPUSINE HYDROXYLA  69.8    0.36 4.1E-05   42.9   0.0  127  547-715   161-289 (294)
485 4D50_A DEOXYHYPUSINE HYDROXYLA  69.8    0.36 4.1E-05   42.9   0.0  127  547-715   161-289 (294)
486 6QH5_A AP-2 complex subunit al  69.7    0.37 4.2E-05   48.8   0.0   67  548-623   330-397 (621)
487 4XL5_C Green fluorescent prote  69.5    0.37 4.2E-05   42.3   0.0   88  600-714   143-230 (263)
488 6LTJ_L Histone H3.2, Histone H  69.2    0.52 4.4E-05   55.1   0.0  106  609-716  1064-1189(1295)
489 5WLC_LM rpS18_uS13, rpS4_eS4,   69.1    0.44 4.4E-05   57.4   0.0  153  548-713  1597-1758(1769)
490 5YVI_A Transportin-1, RNA-bind  69.1    0.37 4.4E-05   49.7   0.0  155  548-714   131-288 (868)
491 3VWA_A Cytoplasmic export prot  68.9    0.42 4.5E-05   49.3   0.0  111  594-715   340-450 (560)
492 3VWA_B Cytoplasmic export prot  68.9    0.42 4.5E-05   49.2   0.0  111  594-715   340-450 (560)
493 3C5W_A PP2A A subunit, PP2A C;  68.8    0.38 4.5E-05   40.3   0.0  109  245-360     7-115 (232)
494 4K92_B CLIP-associating protei  68.6    0.41 4.6E-05   43.1   0.0  109  244-360   129-237 (273)
495 6MQ7_B CLIP-associating protei  68.6    0.41 4.6E-05   43.1   0.0  109  244-360   129-237 (273)
496 4LAC_A Serine/threonine-protei  68.3    0.41 4.7E-05   41.4   0.0  109  245-360   111-219 (258)
497 6MQ5_A CLIP-associating protei  68.0    0.43 4.8E-05   42.3   0.0  108  245-360    49-157 (257)
498 2QK1_A Protein STU2; stu2, Stu  67.9    0.42 4.9E-05   40.9   0.0  116  244-360   103-221 (249)
499 4D4Z_A DEOXYHYPUSINE HYDROXYLA  67.6    0.43   5E-05   42.3   0.0   60  547-623    74-135 (294)
500 4D50_A DEOXYHYPUSINE HYDROXYLA  67.6    0.43   5E-05   42.3   0.0   60  547-623    74-135 (294)

No 1
>1XM9_A plakophilin 1  Plakophilin-1; armadillo repeat, CELL ADHESION; 2.8A {Homo sapiens} SCOP: a.118.1.24
Probab=99.69  E-value=6.3e-22  Score=206.93  Aligned_cols=453  Identities=100%  Similarity=1.422  Sum_probs=304.9  Template_Neff=12.600

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      .++.+..++.+.++.++..++.+|..++...+.....+...++++.+..++.+.+..++..++.++.+++.........+
T Consensus         3 ~l~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~   82 (457)
T 1XM9_A            3 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET   82 (457)
T ss_dssp             CHHHHHHHHHSSCTHHHHHHHHHHHHHTSSCSSHHHHHHHTTHHHHHHHHTTSSCHHHHHHHHHHHHHHHSSCHHHHHHH
T ss_pred             cHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCHHHHHHHHhcCCCHHHHHHHHHHHHHHhhCCHHHHHHH
Confidence            45566777777778889999999999885444444445555778888888888788899999999999886544333444


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFN  405 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~  405 (747)
                      ...+.++.++.++....+..++..++.+|.+++........+..++++.|+.++..+.++|+.+.+.+.....++++...
T Consensus        83 ~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~  162 (457)
T 1XM9_A           83 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFN  162 (457)
T ss_dssp             HHTTCHHHHHHHHTTCCCHHHHHHHHHHHHHHHTSSSTHHHHHHHHHHHCCCCCCHHHHTCC---------CCCHHHHHH
T ss_pred             HhcChHHHHHHHhhhCCCHHHHHHHHHHHHHHhCCHHHHHHHHcchHHHHHHHhccccCCCCCCCCCcccccCCHHHHHH
Confidence            44567777777775344677888899999999875444333335788999999999999999988887777777777766


Q NP_000290.2     406 ATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYR  485 (747)
Q Consensus       406 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  485 (747)
                      +..+|..                     +...+..++.+....|+++.|+.+++.+......+..-.+.+..+|.|++..
T Consensus       163 a~~~L~~---------------------l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~l~~l~~~  221 (457)
T 1XM9_A          163 ATGCLRN---------------------LSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYR  221 (457)
T ss_dssp             HHHHHHH---------------------HTTSHHHHHHHTTSTTHHHHHHHHHHHHHHHTCTTCTTHHHHHHHHHHHTTT
T ss_pred             HHHHHHH---------------------HccChHHHHHHHhcccHHHHHHHHHHHhhhcCcCCHHHHHHHHHHHHHHhcc
Confidence            6665543                     2222223444555567788888887765555556777888999999999999


Q NP_000290.2     486 LDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATL  565 (747)
Q Consensus       486 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eVr  565 (747)
                      .+.+.+..+..+++.++..+..+...+|+.+...+++....+|.++....+......+.+.++++.++.++....+..++
T Consensus       222 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~  301 (457)
T 1XM9_A          222 LDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATL  301 (457)
T ss_dssp             HHHHSCCHHHHHHHTC----------------------------CCCCCSSCCGGGGGGSHHHHHHHHHHHHHCCCHHHH
T ss_pred             cccCCCcchhhhhhcccccccccccccccCcccchhccccccCCCCcccCCCchhHHhhchhHHHHHHHHhccCCCHHHH
Confidence            99999999999999999999999999999999999999999999998888888888888999999999999733556777


Q NP_000290.2     566 EACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLT  645 (747)
Q Consensus       566 ~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~  645 (747)
                      ..++.+|.+++..............+...++++.|+.++.+.++.++..++.+|.+++..+.....+..++++.++.++.
T Consensus       302 ~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~l~~~l~  381 (457)
T 1XM9_A          302 EACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLT  381 (457)
T ss_dssp             HHHHHHHHHHTTCSSSHHHHHHHCCCCCSCCHHHHHHHTTCSCHHHHHHHHHHHHHHHTSGGGHHHHHHHTHHHHHHTTT
T ss_pred             HHHHHHHHHHHhccccccCCcchhhhhhcchHHHHHHHHhcCCHHHHHHHHHHHHHHhcCHHHHHHHHcccHHHHHHHHh
Confidence            78999999998753200000002233456788999999988888999999999999996644432233347777777776


Q NP_000290.2     646 SHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQG  719 (747)
Q Consensus       646 s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~~~~  719 (747)
                      ........++.++..++.+|.+|+...+.....+.+.++++.|..++....++.++..++.+|.+++.+.+.+.
T Consensus       382 ~~~~~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~ll~~~~~~~v~~~a~~~L~~l~~~~~~~~  455 (457)
T 1XM9_A          382 SHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQG  455 (457)
T ss_dssp             SCCSCSTTHHHHHHHHHHHHHHHHTTCTHHHHHHCCHHHHHHHHHHHHCTTCHHHHHHHHHHHHTTSSSTTCSS
T ss_pred             cCCCCCCCCHHHHHHHHHHHHHHHhcCHHHHHHHHhccHHHHHHHHHhCCCCHHHHHHHHHHHHHHhhcHhHhc
Confidence            52000000567888999999999865566666777778889999988862278899999999999998877654


No 2
>3L6X_A Catenin delta-1, E-cadherin; p120, catenin, cadherin, E-cadherin, armadillo; HET: SO4; 2.4A {Homo sapiens}
Probab=99.41  E-value=1.1e-17  Score=185.51  Aligned_cols=438  Identities=32%  Similarity=0.540  Sum_probs=299.3  Template_Neff=11.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFR-STTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~-~~~~~~  323 (747)
                      ..++.++.++...++.++..++.+|.+++.........+...++++.|+.++.+.+..++..++.+|.+++.. ......
T Consensus        48 ~~l~~li~~L~~~~~~v~~~a~~~L~~L~~~~~~~~~~~~~~g~i~~Lv~lL~~~~~~v~~~a~~~L~~l~~~~~~~~~~  127 (584)
T 3L6X_A           48 PELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKI  127 (584)
T ss_dssp             CCHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHGGGCSSHHHHHHHHHHHHHHTSSSCHHHHH
T ss_pred             CcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCChHHHHHHHHCCcHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCCHHHHH
Confidence            4566677777777788899999999998854444444455567888888888887788999999999999864 333444


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMS--REVVDPE  401 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL~~~~~~~~~~~~~~~--~~~~~~~  401 (747)
                      .+...+.++.++.++....+..++..++.+|.+++........++..++..|+.++..+.++|........  ....+++
T Consensus       128 ~~~~~~~i~~L~~ll~~~~~~~v~~~a~~~L~~L~~~~~~~~~l~~~~l~~L~~~l~~~~~~~~~~~~~~~~~~~~~~~~  207 (584)
T 3L6X_A          128 AIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWES  207 (584)
T ss_dssp             HHHHTTHHHHHHHHHHHCCSHHHHHHHHHHHHHHTTSGGGHHHHHHHTHHHCCCCCCHHHHCCC----------CCCCHH
T ss_pred             HHHcCChHHHHHHHHHHcCCHHHHHHHHHHHHHHhcCHHHHHHHHHHHHHHHHHhccccCCCCCCCCCcCCCCcccChHH
Confidence            44555778888888863346678889999999998765544444445778888888888877754332211  1223455


Q NP_000290.2     402 VFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSAD-AGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH  480 (747)
Q Consensus       402 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  480 (747)
                      +..++.++|+.                     ++..+ ..++.++...|+++.|+..++.++....-+.+.+++|.++|.
T Consensus       208 v~~~a~~~L~~---------------------l~~~~~~~~~~l~~~~g~v~~L~~~l~~~~~~~~~~~~~~~~a~~~L~  266 (584)
T 3L6X_A          208 VLTNTAGCLRN---------------------VSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR  266 (584)
T ss_dssp             HHHHHHHHHHH---------------------HTSSCHHHHHHHHHSTTHHHHHHHHHHHHHHTTCCSCHHHHHHHHHHH
T ss_pred             HHHHHHHHHHH---------------------HhcCCHHHHHHHHhCCCHHHHHHHHHHHHhcCCCCChHHHHHHHHHHH
Confidence            66666665543                     22222 245556666789999999888765544557788999999999


Q NP_000290.2     481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSK  560 (747)
Q Consensus       481 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~  560 (747)
                      ||++..+.++|...+..+....           ..+              +-...+......+.+.++++.|+.++....
T Consensus       267 ~L~~~~~~~~~~~~~~~~~~~~-----------~~~--------------~~~~~~~~~~~~l~~~~~~~~l~~ll~~~~  321 (584)
T 3L6X_A          267 NLSYQVHREIPQAERYQEAAPN-----------VAN--------------NTGTSPARGYELLFQPEVVRIYISLLKESK  321 (584)
T ss_dssp             HHHTTHHHHSTTCCC---------------------------------------CCCCGGGGGGSHHHHHHHHHHHHHCC
T ss_pred             HHHhhhhccChhHHHHHHhcCc-----------CCC--------------CCCCCChhhhhHhhChhHHHHHHHHHHcCC
Confidence            9999998888765554432110           000              111222233344567889999999998423


Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEV  640 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~L  640 (747)
                      ++.++..++.+|.+++......... ....+.+.++++.|+.++.+.++.++..++++|.+|+........+..++++.|
T Consensus       322 ~~~~~~~a~~~L~~L~~~~~~~~~~-~~~~~~~~~~l~~L~~ll~~~~~~v~~~a~~~L~~L~~~~~~~~~l~~~~l~~L  400 (584)
T 3L6X_A          322 TPAILEASAGAIQNLCAGRWTYGRY-IRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNL  400 (584)
T ss_dssp             CHHHHHHHHHHHHHHHSSCSHHHHH-HHHHHTSHHHHHHHHHGGGCSCHHHHHHHHHHHHHHHTTCSCHHHHHHHHHHHH
T ss_pred             CHHHHHHHHHHHHHHhCCCccCCHH-HHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHhcChHHHHHHHcchHHHH
Confidence            7788899999999998742100000 233445678899999999988889999999999999877444333334677888


Q NP_000290.2     641 TRLLTSHTGNT--SNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSS-ASPKAAEAARLLLSDMWSSKEL  717 (747)
Q Consensus       641 l~LL~s~s~~~--~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~-~d~eVr~aAL~aLsnL~~~~~~  717 (747)
                      +.++.......  ..+..++..++.+|.+++...+.....+.+.++++.|+.++... .+..++..|+.+|.+++...+.
T Consensus       401 ~~~L~~~~~~~~~~~~~~~~~~~l~~L~~l~~~~~~~~~~l~~~~~l~~L~~ll~~~~~~~~v~~~a~~~L~~l~~~~~~  480 (584)
T 3L6X_A          401 VKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKEL  480 (584)
T ss_dssp             HHTSSSSSCSGGGTCCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHTCSSSCHHHHHHHHHHHHHHHTSHHH
T ss_pred             HHcCCCCCCCCCcCCCHHHHHHHHHHHHHHHhcCHHHHHHHHHCCHHHHHHHHHhcCCCCHHHHHHHHHHHHHHhCCHHH
Confidence            88776521000  00344577889999998876666777777888899999988653 1478899999999999999999


Q NP_000290.2     718 QGVLRQQGFDRN  729 (747)
Q Consensus       718 ~~~~~~~~~~~~  729 (747)
                      ...+.+.|+-..
T Consensus       481 ~~~l~~~g~~~~  492 (584)
T 3L6X_A          481 RKPLEKEGWKKS  492 (584)
T ss_dssp             HHHHHTTTCCGG
T ss_pred             HHHHHHcCCchh
Confidence            999998888766


No 3
>5D5K_C Importin subunit alpha-1, Poly [ADP-ribose]; PARP-2 NLS, PARP-2, poly(ADP-ribose)polymerase-2, Importin; 1.9A {Mus musculus}
Probab=98.56  E-value=1.1e-11  Score=126.19  Aligned_cols=369  Identities=14%  Similarity=0.172  Sum_probs=230.1  Template_Neff=13.100

Q NP_000290.2     243 SGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESA-KQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTT  320 (747)
Q Consensus       243 ~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~-~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~  320 (747)
                      ....++.+...+.+.++.++..++.++..+....... ...+...++++.++..+. ..++.++..++.++..++.....
T Consensus        11 ~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~   90 (466)
T 5D5K_C           11 VNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSE   90 (466)
T ss_dssp             CSCCHHHHHHHHTSSCHHHHHHHHHHHHHHHTCSSCCCHHHHHHTTHHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHH
T ss_pred             cCcCHHHHHHHHccCCHHHHHHHHHHHHHHHhcCCCCCHHHHHHcCcHHHHHHHhhCCCChHHHHHHHHHHHHHcCCChH
Confidence            4456667777777778888999999998887643221 122333456777777776 34567888899999888764443


Q NP_000290.2     321 NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVV  398 (747)
Q Consensus       321 ~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~  398 (747)
                      ....+...++++.+...+. ..++.++..++.++..++..... ...+.. ++++.+..++..+.           .+..
T Consensus        91 ~~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~-----------~~~~  158 (466)
T 5D5K_C           91 QTKAVVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPD-----------LSTL  158 (466)
T ss_dssp             HHHHHHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHTTCSSC-----------GGGS
T ss_pred             HHHHHhccchHHHHHHHhc-CCCCcHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhhCCC-----------cccc
Confidence            3333444457777888876 56778888999999998875432 222333 67777777776421           1112


Q NP_000290.2     399 DPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCV  478 (747)
Q Consensus       399 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  478 (747)
                      ++++...+..++..-.                     .............+++..+...++.      -+..-...+...
T Consensus       159 ~~~~~~~a~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~  211 (466)
T 5D5K_C          159 ACGYLRNLTWTLSNLC---------------------RNKNPAPPLDAVEQILPTLVRLLHH------NDPEVLADSCWA  211 (466)
T ss_dssp             CHHHHHHHHHHHHHHS---------------------CCCSSCCCHHHHHHHHHHHHHHTTS------SCHHHHHHHHHH
T ss_pred             cHHHHHHHHHHHHHHH---------------------cCCCCCCChHHHHHHHHHHHHHHcC------CCHHHHHHHHHH
Confidence            3334444433332211                     1011111111123444444443321      112222223333


Q NP_000290.2     479 LHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK  558 (747)
Q Consensus       479 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s  558 (747)
                      |.++...-                                                  ......+.+.++++.++.++. 
T Consensus       212 l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-  240 (466)
T 5D5K_C          212 ISYLTDGP--------------------------------------------------NERIEMVVKKGVVPQLVKLLG-  240 (466)
T ss_dssp             HHHHTSSC--------------------------------------------------HHHHHHHHTTTCHHHHHHHHT-
T ss_pred             HHHHhcCC--------------------------------------------------chHHHHHHHCChHHHHHHHhc-
Confidence            33332110                                                  001111234567888888887 


Q NP_000290.2     559 SKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQV  636 (747)
Q Consensus       559 s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~gi  636 (747)
                      +.++.++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.. +.. ..+...++
T Consensus       241 ~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~  315 (466)
T 5D5K_C          241 ATELPIVTPALRAIGNIVTGTDE-----QTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGL  315 (466)
T ss_dssp             CSCHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTGGGGHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTC
T ss_pred             CCCchHHHHHHHHHHHHhcCCHH-----HHHHHHccChhHhHHHHhhCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCH
Confidence            46778888999999999875332     233334567888999999888889999999999999876 322 23344567


Q NP_000290.2     637 FPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS-QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       637 I~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~-s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      ++.+..++.+      .++.++..++.+|.+++.. .......+.+.++++.+..++.+. ++.++..++.+|.+++.
T Consensus       316 ~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~l~~l~~  386 (466)
T 5D5K_C          316 VPFLVGVLSK------ADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAK-DTKIIQVILDAISNIFQ  386 (466)
T ss_dssp             HHHHHHHHHS------SCHHHHHHHHHHHHHHHHHSCHHHHHHHHHTTCHHHHHHGGGCS-CHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCCHHHHHHHHhCCcHHHHHHHhhcC-CHHHHHHHHHHHHHHHH
Confidence            8888888876      3678889999999999874 233344455556788888888866 78899999999999987


No 4
>3NMZ_A APC variant protein, Rho guanine; protein-protein complex, armadillo repeats, CELL; 3.01A {Homo sapiens}
Probab=98.55  E-value=1.3e-11  Score=128.97  Aligned_cols=381  Identities=18%  Similarity=0.200  Sum_probs=233.7  Template_Neff=12.000

Q NP_000290.2     238 EDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQN------------VQQ  305 (747)
Q Consensus       238 ~~~~~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~e------------Vr~  305 (747)
                      .+..+...+++.++.++...+...   ++.+|..++.. ......+...+.++.+..++...+..            ++.
T Consensus        25 ~~~~~~~~~i~~l~~~l~~~~~~~---a~~~L~~l~~~-~~~~~~~~~~g~i~~L~~ll~~~~~~~~~~~~~~~~~~v~~  100 (458)
T 3NMZ_A           25 SHLGTKVEMVYSLLSMLGTHDKDD---MSRTLLAMSSS-QDSCISMRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKEARA  100 (458)
T ss_pred             HHhHhccchHHHHHHHhCCCCHHH---HHHHHHHHhCC-chHHHHHHHcCcHHHHHHHhcCCChhhcCCCCcccCHHHHH
Confidence            344445556677777776554443   77778777643 23333444556778888888765555            888


Q NP_000290.2     306 AAAGALRNLVFRST---TNKLETRRQNGIREAVSLLR--------------------RTGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       306 ~AL~aLs~La~~~~---~~~~~ll~~~IL~~Ll~lL~--------------------ss~d~eVr~~AL~aLsnLas~~~  362 (747)
                      .++.+|.+++...+   .....+...+.++.+...+.                    ...+..++..++.++.+++....
T Consensus       101 ~a~~~L~~l~~~~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~a~~~L~~l~~~~~  180 (458)
T 3NMZ_A          101 RASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEE  180 (458)
T ss_pred             HHHHHHHHHHcCCCCCHHHHHHHHHCCcHHHHHHHHHhhhhcccchhhHHHHHHhcCCCChHHHHHHHHHHHHHHcCChH
Confidence            99999999885432   22222222334444444421                    01234455667778887776554


Q NP_000290.2     363 LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSA-DAG  440 (747)
Q Consensus       363 ~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~  440 (747)
                      ....+.. ++++.|+.++.......    .... ...++++...+..+|..                     +... +..
T Consensus       181 ~~~~~~~~~~~~~l~~~l~~~~~~~----~~~~-~~~~~~~~~~a~~~L~~---------------------l~~~~~~~  234 (458)
T 3NMZ_A          181 HRHAMNELGGLQAIAELLQVDCEMY----GLTN-DHYSITLRRYAGMALTN---------------------LTFGDVAN  234 (458)
T ss_pred             HHHHHHHCChHHHHHHHHhccccCC----CCCC-CCCCHHHHHHHHHHHHH---------------------HHcCCHHH
Confidence            4444444 77888888877532211    1110 11244554444444432                     1111 111


Q NP_000290.2     441 RQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDK  520 (747)
Q Consensus       441 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  520 (747)
                      ++.+....|+++.|...++.      .+..-.+.+..+|.|++..-+.                                
T Consensus       235 ~~~~~~~~~~i~~l~~~l~~------~~~~~~~~a~~~L~~l~~~~~~--------------------------------  276 (458)
T 3NMZ_A          235 KATLCSMKGCMRALVAQLKS------ESEDLQQVIASVLRNLSWRADV--------------------------------  276 (458)
T ss_pred             HHHHHHhCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHHCCCCh--------------------------------
Confidence            22233445667777666542      2334445555566665431100                                


Q NP_000290.2     521 MMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLK-EKGLPQ  599 (747)
Q Consensus       521 ~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie-~giI~~  599 (747)
                                       .....+.+.++++.|+.++....+..++..++++|.+++...+.     ....+.. .++++.
T Consensus       277 -----------------~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~~  334 (458)
T 3NMZ_A          277 -----------------NSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTE-----NKADICAVDGALAF  334 (458)
T ss_pred             -----------------hHHHHHHHCCHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCch-----hHHHHHHhcChHHH
Confidence                             01122356678888888887325667888999999999874332     2233344 778888


Q NP_000290.2     600 IARLLQS----GNSDVVRSGASLLSNMSR---H-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       600 Ll~LL~s----~d~eVr~~AL~aLsnLa~---~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      |+.++..    .+..++..++.+|.+++.   . ... ..+...++++.|+.++..      .++.++..++++|.+++.
T Consensus       335 l~~~l~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~l~~~~~~~~l~~~l~~------~~~~v~~~a~~~L~~l~~  408 (458)
T 3NMZ_A          335 LVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKS------HSLTIVSNACGTLWNLSA  408 (458)
T ss_pred             HHHHHcCCCCCCCHHHHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhCC------CCHHHHHHHHHHHHHHHC
Confidence            8888872    346778889999988863   2 222 233456788888888876      367889999999999998


Q NP_000290.2     671 SQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       671 ~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ..+.....+.+.++++.|..++.+. ++.++..++.+|.+++...
T Consensus       409 ~~~~~~~~l~~~~~~~~L~~ll~~~-~~~v~~~a~~~L~~l~~~~  452 (458)
T 3NMZ_A          409 RNPKDQEALWDMGAVSMLKNLIHSK-HKMIAMGSAAALRNLMANR  452 (458)
T ss_pred             CCHHHHHHHHHCCcHHHHHHHHhCC-CHHHHHHHHHHHHHHHcCC
Confidence            5566677777778899999988876 6778999999999998654


No 5
>4UAF_B Importin alpha 1 import receptor; importin karyopherin complex NLS, PROTEIN; HET: PO4; 1.698A {Mus musculus}
Probab=98.54  E-value=1.3e-11  Score=125.71  Aligned_cols=369  Identities=14%  Similarity=0.172  Sum_probs=229.2  Template_Neff=13.100

Q NP_000290.2     243 SGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESA-KQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTT  320 (747)
Q Consensus       243 ~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~-~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~  320 (747)
                      ....++.+...+.+.++.++..++.++..+....... ...+...++++.++..+. ..++.++..++.++..++.....
T Consensus        11 ~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~   90 (466)
T 4UAF_B           11 VNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSE   90 (466)
T ss_pred             cCcCHHHHHHHHccCCHHHHHHHHHHHHHHHhcCCCCCHHHHHHcCcHHHHHHHhhCCCChHHHHHHHHHHHHHhcCChH
Confidence            4456667777777778888999999998887643221 122333456777777776 34567888899999888764443


Q NP_000290.2     321 NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVV  398 (747)
Q Consensus       321 ~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~  398 (747)
                      ....+...++++.+...+. ..++.++..++.++..++..... ...+.. ++++.+..++..+.           .+..
T Consensus        91 ~~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~-----------~~~~  158 (466)
T 4UAF_B           91 QTKAVVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPD-----------LSTL  158 (466)
T ss_pred             HHHHHHccChHHHHHHHhc-CCCCCHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhhCCC-----------cccc
Confidence            3333444457777888876 56778888999999998875432 222233 67777777775421           1112


Q NP_000290.2     399 DPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCV  478 (747)
Q Consensus       399 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  478 (747)
                      ++++...+..++..-.                     .............+++..+...+..      -+..-...+...
T Consensus       159 ~~~~~~~~~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~  211 (466)
T 4UAF_B          159 ACGYLRNLTWTLSNLC---------------------RNKNPAPPLDAVEQILPTLVRLLHH------NDPEVLADSCWA  211 (466)
T ss_pred             cHHHHHHHHHHHHHHH---------------------cCCCCCCChhHHHHHHHHHHHHHcC------CCHHHHHHHHHH
Confidence            3334333333332211                     0001111111113344444433321      111222222333


Q NP_000290.2     479 LHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK  558 (747)
Q Consensus       479 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s  558 (747)
                      |.++...-                                                  ......+.+.++++.++.++. 
T Consensus       212 l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-  240 (466)
T 4UAF_B          212 ISYLTDGP--------------------------------------------------NERIEMVVKKGVVPQLVKLLG-  240 (466)
T ss_pred             HHHHhcCC--------------------------------------------------cHHHHHHHHCChHHHHHHHhc-
Confidence            33332110                                                  001112245567888888887 


Q NP_000290.2     559 SKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQV  636 (747)
Q Consensus       559 s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~gi  636 (747)
                      +.++.++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.. +.. ..+...++
T Consensus       241 ~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~  315 (466)
T 4UAF_B          241 ATELPIVTPALRAIGNIVTGTDE-----QTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGL  315 (466)
T ss_pred             CCChhHHHHHHHHHHHHhcCCHH-----HHHHHhccCHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCH
Confidence            46778888999999999875332     233334567888899999888889999999999999876 322 23344567


Q NP_000290.2     637 FPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS-QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       637 I~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~-s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      ++.+..++.+      .++.++..++.+|.+++.. .+.....+.+.++++.+..++.+. ++.++..++.+|.+++.
T Consensus       316 ~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~l~~l~~  386 (466)
T 4UAF_B          316 VPFLVGVLSK------ADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAK-DTKIIQVILDAISNIFQ  386 (466)
T ss_pred             HHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCCHHHHHHHHhCCcHHHHHHHhhcC-CHHHHHHHHHHHHHHHH
Confidence            8888888876      3678889999999999874 233344455556788888888876 78899999999999987


No 6
>4U5L_A deltaIBB-importin-alpha1; TPX2, inhibitor, TRANSPORT PROTEIN; HET: 3D6; 2.53A {Mus musculus}
Probab=98.52  E-value=1.7e-11  Score=122.96  Aligned_cols=360  Identities=16%  Similarity=0.184  Sum_probs=217.1  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+. ..++.++..++.++..++...+.....+...++++.+...+.+.++.++..++.++..++.........
T Consensus        49 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  128 (426)
T 4U5L_A           49 LIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDL  128 (426)
T ss_dssp             CHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHHTCHHHHHH
T ss_pred             cHHHHHHHhccCCChHHHHHHHHHHHHHhCCCHHHHHHHHhcCcHHHHHHHhcCCChHHHHHHHHHHHHHhcCCHHHHHH
Confidence            4555666665 445678888899998887654433334444567778888888778888999999999988654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAE-----IQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~e-----Vr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      +...++++.+...+. .....     ++..++.++..++..........  .++++.+..++..                
T Consensus       129 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------  191 (426)
T 4U5L_A          129 VIKHGAIDPLLALLA-VPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHH----------------  191 (426)
T ss_dssp             HHHTTCHHHHHHTTC-SSCGGGSCHHHHHHHHHHHHHHTCCCSSCCCHHHHHHHHHHHHHHTTS----------------
T ss_pred             HHHCCcHHHHHHHhh-CCCCchhhHHHHHHHHHHHHHHHcCCCCCCCccHHHHHHHHHHHHHhC----------------
Confidence            334456677777765 32222     67778888888776433222221  2555666665542                


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                      .|+++...+..++..-....      +              .....+. -.+++..|...+..      .+..-...+..
T Consensus       192 ~~~~~~~~a~~~l~~l~~~~------~--------------~~~~~~~-~~~~~~~l~~~l~~------~~~~~~~~a~~  244 (426)
T 4U5L_A          192 NDPEVLADSCWAISYLTDGP------N--------------ERIEMVV-KKGVVPQLVKLLGA------TELPIVTPALR  244 (426)
T ss_dssp             SCHHHHHHHHHHHHHHTSSC------H--------------HHHHHHH-TTTCHHHHHHHHTC------SCHHHHHHHHH
T ss_pred             CCHHHHHHHHHHHHHHhhCC------c--------------HHHHHHh-hcChHHHHHHHhcC------CCccHHHHHHH
Confidence            13444444444443211100      0              0000000 12233333333221      11122222333


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      .|.++...-                                                  ......+.+.++++.+..++.
T Consensus       245 ~l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~  274 (426)
T 4U5L_A          245 AIGNIVTGT--------------------------------------------------DEQTQKVIDAGALAVFPSLLT  274 (426)
T ss_dssp             HHHHHTTSC--------------------------------------------------HHHHHHHHHTTGGGGHHHHTT
T ss_pred             HHHHHhcCC--------------------------------------------------HHHHHHHhccchHHHHHHHhc
Confidence            333332100                                                  001112245567888888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGN  634 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~  634 (747)
                       +.++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.. . .. ..+...
T Consensus       275 -~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~  348 (426)
T 4U5L_A          275 -NPKTNIQKEATWTMSNITAGRQD-----QIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHC  348 (426)
T ss_dssp             -CSSHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTCHHHHHHHHHSSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHT
T ss_pred             -CCChHHHHHHHHHHHHHhcCCHH-----HHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHHHHhC
Confidence             46778888999999999875332     233334557888899998888888999999999999875 2 22 233445


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS------QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~------s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      ++++.+..++.+      .++.++..++.+|.+++..      .+.....+.+.++++.+..++.+. ++.++..++.++
T Consensus       349 ~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~l~~ll~~~-~~~v~~~a~~~l  421 (426)
T 4U5L_A          349 GIIEPLMNLLSA------KDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHE-NESVYKASLNLI  421 (426)
T ss_dssp             TCHHHHHHGGGS------CCHHHHHHHHHHHHHHHHHHHTTTCHHHHHHHHHHTTHHHHHHGGGGSS-CHHHHHHHHHHH
T ss_pred             CcHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHHHHhcCchHHHHHHHHcCHHHHHHHHHhCC-CHHHHHHHHHHH
Confidence            678888888876      3678899999999999763      123333444556788888888776 788898888888


Q NP_000290.2     709 SDMW  712 (747)
Q Consensus       709 snL~  712 (747)
                      .++.
T Consensus       422 ~~~~  425 (426)
T 4U5L_A          422 EKYF  425 (426)
T ss_dssp             HHHC
T ss_pred             HHHc
Confidence            7764


No 7
>6SA7_B DARPin-Armadillo fusion C8long83; protein fusion, DARPin, Armadillo, shared; 3.3A {synthetic construct}
Probab=98.48  E-value=2.5e-11  Score=127.02  Aligned_cols=136  Identities=24%  Similarity=0.253  Sum_probs=93.8  Template_Neff=12.500

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.++.++..++.+|..++.........+...++++.+...+.+.++.++..++.++..++........
T Consensus       172 ~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~  251 (510)
T 6SA7_B          172 KKILKDLVKKLSSPNENELQNALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQ  251 (510)
T ss_dssp             HHHHHHHHHHTTCSSHHHHHHHHHHHHHHHHTCHHHHHHHHHHTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHH
T ss_pred             HHHHHHHHHHhcCCChHHHHHHHHHHHHHhcCChHHHHHHHHcCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHH
Confidence            45666777777777788889999999998765544444444556788888888887888999999999998765443333


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      .+...++++.+...+. +.++.++..++.++..++..... ...+.. ++++.|+.++.
T Consensus       252 ~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  309 (510)
T 6SA7_B          252 AVIDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLS  309 (510)
T ss_dssp             HHHHTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHHHcCcHHHHHHHcc-CCCHHHHHHHHHHHHHHhcCChHHHHHHHHcChHHHHHHHhc
Confidence            3444567777777775 55677888888888888754322 222222 56666666664


No 8
>4RV1_D Engineered Protein OR497; STRUCTURAL GENOMICS, PSI-BIOLOGY, PROTEIN STRUCTURE; 2.573A {SYNTHETIC CONSTRUCT}
Probab=98.47  E-value=2.7e-11  Score=120.80  Aligned_cols=362  Identities=20%  Similarity=0.254  Sum_probs=220.3  Template_Neff=13.300

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETR  326 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll  326 (747)
                      ++.+...+.+.++.++..++.++..+..............++++.+...+.+.++.++..++.++..++...........
T Consensus         4 ~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~   83 (420)
T 4RV1_D            4 VEKLVKLLTSTDSETQKEAARDLAEIASGPASAIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIV   83 (420)
T ss_dssp             HHHHHHHHHCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHTTSCSCSSSHHHHHHHHHHHTTSCHHHHHHHH
T ss_pred             HHHHHHHhcCCCHHHHHHHHHHHHHHhcCcHHHHHHHHHCCHHHHHHHHcCCCCHHHHHHHHHHHHHHhcCCHHHHHHHH
Confidence            44556666677788888999999888765433333333446677777888777788899999999888765433323333


Q NP_000290.2     327 RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFF  404 (747)
Q Consensus       327 ~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~  404 (747)
                      ..++++.+...+. +.++.++..++.++..+..... ....+.. ++++.+..++..                .++++..
T Consensus        84 ~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~~~~  146 (420)
T 4RV1_D           84 DAGGVEVLVKLLT-STDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVKLLTS----------------TDSEVQK  146 (420)
T ss_dssp             HTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTC----------------SCHHHHH
T ss_pred             HcChHHHHHHHhc-CCCHHHHHHHHHHHHHHhCCChHHHHHHHHcCHHHHHHHHHhC----------------CCHHHHH
Confidence            3456677777776 5567788889999988876432 2222222 566666666542                1344444


Q NP_000290.2     405 NATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSY  484 (747)
Q Consensus       405 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  484 (747)
                      .+..++..-....      +              .....+. ..+++..+...++.      .+..-...+..+|.++..
T Consensus       147 ~a~~~l~~l~~~~------~--------------~~~~~~~-~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~  199 (420)
T 4RV1_D          147 EAARALANIASGP------D--------------EAIKAIV-DAGGVEVLVKLLTS------TDSEVQKEAARALANIAS  199 (420)
T ss_dssp             HHHHHHHHHHTSC------H--------------HHHHHHH-HTTHHHHHHHHTTC------SSHHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHhcCC------H--------------HHHHHHH-HCCHHHHHHHHhcC------CCHHHHHHHHHHHHHHhC
Confidence            4443332211000      0              0000000 01333333333221      111111222222222211


Q NP_000290.2     485 RLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDAT  564 (747)
Q Consensus       485 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eV  564 (747)
                      ..                                                  ......+.+.++++.+...+. +.++.+
T Consensus       200 ~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~~~  228 (420)
T 4RV1_D          200 GP--------------------------------------------------TSAIKAIVDAGGVEVLVKLLT-STDSEV  228 (420)
T ss_dssp             SC--------------------------------------------------HHHHHHHHTTTHHHHHHHHTT-CSCHHH
T ss_pred             CC--------------------------------------------------HHHHHHHHHCCHHHHHHHHhh-CCCHHH
Confidence            00                                                  000111234456777888887 467788


Q NP_000290.2     565 LEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL-L-HRVMGNQVFPEVTR  642 (747)
Q Consensus       565 r~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e-~-~~ll~~giI~~Ll~  642 (747)
                      +..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.... . ..+...++++.+..
T Consensus       229 ~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~  303 (420)
T 4RV1_D          229 QKEAARALANIASGPDE-----AIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVK  303 (420)
T ss_dssp             HHHHHHHHHHHHTSCHH-----HHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHH
T ss_pred             HHHHHHHHHHHhCCCHH-----HHHHHhhccHHHHHHHHhCCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHH
Confidence            88999999998864332     12233456788888888888888899999999999987632 2 23344467777888


Q NP_000290.2     643 LLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       643 LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ++.+      .++.++..++.+|.+++...+.....+...+.++.+..++.+. ++.++..++.+|.+++...
T Consensus       304 ~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~a~~~l~~l~~~~  369 (420)
T 4RV1_D          304 LLTS------TDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVKLLTST-DSEVQKEAARALANIASGP  369 (420)
T ss_dssp             HTTC------SCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCS-CHHHHHHHHHHHHHHHTSC
T ss_pred             HccC------CCHHHHHHHHHHHHHHHcChHHHHHHHHHCCHHHHHHHHhCCC-CHHHHHHHHHHHHHHHcCC
Confidence            7776      3678899999999999876444444455556788888888766 7889999999999998764


No 9
>6S9O_F designed Armadillo repeat protein with; peptide binder, repeat protein, designed; HET: CA, EDO; 3.17A {synthetic construct}
Probab=98.47  E-value=2.8e-11  Score=117.85  Aligned_cols=167  Identities=20%  Similarity=0.267  Sum_probs=122.0  Template_Neff=13.100

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++++.++.++. +.++.++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.
T Consensus       170 ~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~  243 (344)
T 6S9O_F          170 DAGALPALVQLLS-SPNEQILQLALWALSNIASGGNE-----QIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIAS  243 (344)
T ss_dssp             HTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHH-----HHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTT
T ss_pred             hCCcHHHHHHHcc-CCCHHHHHHHHHHHHHHHcCChH-----HHHHHHhcChHHHHHHHccCCCHHHHHHHHHHHHHHHc
Confidence            4456777888887 46777888899999998864332     12333445788888888888888899999999999986


Q NP_000290.2     625 H-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAE  702 (747)
Q Consensus       625 ~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~  702 (747)
                      . ... ......++++.+..++.+      .++.++..++.+|.+++...+.....+.+.++++.+..++.+. ++.++.
T Consensus       244 ~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~  316 (344)
T 6S9O_F          244 GGNEQIQAVIDAGALPALVQLLSS------PNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHE-NEKIQK  316 (344)
T ss_dssp             SCHHHHHHHHHTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGCS-CHHHHH
T ss_pred             CcHHHHHHHHHCChHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCHHHHHHHHhhCC-CHHHHH
Confidence            5 222 233445677778887766      3678889999999999876555555555556788888888766 788999


Q NP_000290.2     703 AARLLLSDMWSSKELQGVLRQQ  724 (747)
Q Consensus       703 aAL~aLsnL~~~~~~~~~~~~~  724 (747)
                      .++.+|.+++...+.....+..
T Consensus       317 ~a~~~l~~l~~~~~~~~~~~~~  338 (344)
T 6S9O_F          317 EAQEALEKLQSHGSGGSGKRKR  338 (344)
T ss_dssp             HHHHHHHHHHHCSCCCCCCCBC
T ss_pred             HHHHHHHHHHhcccCCCchhcc
Confidence            9999999998776654444333


No 10
>5MFD_C YIIIM''6AII, Capsid decoration protein,pD_(KR)5; Designed armadillo repeat protein, peptide; HET: CA; 2.3A {synthetic construct}
Probab=98.46  E-value=3e-11  Score=116.21  Aligned_cols=318  Identities=20%  Similarity=0.263  Sum_probs=178.1  Template_Neff=13.300

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+....+.....+...++++.+...+.+.++.++..++.++..+..........+
T Consensus         5 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~   84 (328)
T 5MFD_C            5 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAV   84 (328)
T ss_dssp             CHHHHHHHHHSSCHHHHHHHHHHHHHHHTSCHHHHHHHHHHTCHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCcHHHHHHH
Confidence            45556666666777888889999988876544333334445677788888877778888889998888875433322223


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++..                .++++.
T Consensus        85 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~~~  147 (328)
T 5MFD_C           85 IDAGALPALVQLLS-SPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSS----------------PNEQIL  147 (328)
T ss_dssp             HHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGC----------------SCHHHH
T ss_pred             hhcCHHHHHHHHcc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHhcC----------------CCHHHH
Confidence            33345666666665 4455666777777777665321 1111111 334444433321                011111


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..                                                                     ++..|.++.
T Consensus       148 ~~---------------------------------------------------------------------a~~~l~~l~  158 (328)
T 5MFD_C          148 QE---------------------------------------------------------------------ALWTLGNIA  158 (328)
T ss_dssp             HH---------------------------------------------------------------------HHHHHHHHT
T ss_pred             HH---------------------------------------------------------------------HHHHHHHHH
Confidence            11                                                                     111222221


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ...+                                                  .....+.+.++++.++.++. +.++.
T Consensus       159 ~~~~--------------------------------------------------~~~~~~~~~~~~~~l~~~l~-~~~~~  187 (328)
T 5MFD_C          159 SGGN--------------------------------------------------EQIQAVIDAGALPALVQLLS-SPNEQ  187 (328)
T ss_dssp             TSCH--------------------------------------------------HHHHHHHHTTHHHHHHHGGG-CSCHH
T ss_pred             cCCH--------------------------------------------------HHHHHHHHCCcHHHHHHHhc-CCCHH
Confidence            0000                                                  00000122345556666665 35556


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFPEVT  641 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~~Ll  641 (747)
                      ++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.++.+++.. +.. ......++++.+.
T Consensus       188 ~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~  262 (328)
T 5MFD_C          188 ILQEALWTLGNIASGGNE-----QIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALV  262 (328)
T ss_dssp             HHHHHHHHHHHHHTSCHH-----HHHHHHHTTCHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHH
T ss_pred             HHHHHHHHHHHHHcCCHH-----HHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHH
Confidence            666777777777654221     122223445667777777666667777777777777654 222 2223345666666


Q NP_000290.2     642 RLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMW  712 (747)
Q Consensus       642 ~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~  712 (747)
                      .++.+      .++.++..++.+|.+++...+.....+.+.++++.+..++.+. ++.++..++.+|.+++
T Consensus       263 ~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~  326 (328)
T 5MFD_C          263 QLLSS------PNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQSHE-NEKIQKEAQEALEKLQ  326 (328)
T ss_dssp             HGGGC------SCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHGGGCS-CHHHHHHHHHHHHHHH
T ss_pred             HHhcC------CCHHHHHHHHHHHHHHhCCcHHHHHHHHHCCHHHHHHHHhhCC-CHHHHHHHHHHHHHHh
Confidence            66655      2566777777777777765444444444445667777777655 6677777777777665


No 11
>4MZ6_E Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin; ARM repeat, protein transport, Importin; 1.88A {Mus musculus}
Probab=98.45  E-value=3.5e-11  Score=125.01  Aligned_cols=368  Identities=14%  Similarity=0.178  Sum_probs=227.8  Template_Neff=12.800

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAK-QQVYQLGGICKLVDLLRSPN-QNVQQAAAGALRNLVFRSTTN  321 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~-~~li~~~IL~~Ll~lL~s~d-~eVr~~AL~aLs~La~~~~~~  321 (747)
                      ..+++.+...+.+.++.++..++.++..+........ ..+...++++.+...+...+ +.++..++.++..++......
T Consensus        56 ~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~~  135 (509)
T 4MZ6_E           56 NWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQ  135 (509)
T ss_dssp             TCCHHHHHHHHTTCCHHHHHHHHHHHHHHHTCSSCCCHHHHHHTTHHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHH
T ss_pred             hhhHHHHHHHHcCCCHHHHHHHHHHHHHHHcCCCCCCHHHHHHCCcHHHHHHHhcCCCChHHHHHHHHHHHHHhCCCHHH
Confidence            4456667777777788889999999988876433211 22333456777777776543 678888999998887654433


Q NP_000290.2     322 KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVD  399 (747)
Q Consensus       322 ~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~  399 (747)
                      ...+...++++.+...+. ..++.++..++.++..++..... ...+.. ++++.|+.++.....           +..+
T Consensus       136 ~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~-----------~~~~  203 (509)
T 4MZ6_E          136 TKAVVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDL-----------STLA  203 (509)
T ss_dssp             HHHHHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHHTCSSCG-----------GGSC
T ss_pred             HHHHHhcChHHHHHHHhc-CCChhHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHHhCCCh-----------hhhh
Confidence            333444467777888886 56778889999999998875432 222223 677777777764211           1122


Q NP_000290.2     400 PEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVL  479 (747)
Q Consensus       400 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  479 (747)
                      +++...+..+|..-.                     .............+++..+...+..      -+......+...|
T Consensus       204 ~~~~~~~~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l  256 (509)
T 4MZ6_E          204 CGYLRNLTWTLSNLC---------------------RNKNPAPPLDAVEQILPTLVRLLHH------NDPEVLADSCWAI  256 (509)
T ss_dssp             HHHHHHHHHHHHHHH---------------------CCCSSCCCHHHHHHHHHHHHHHTTC------SCHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHh---------------------cCCCCCCCHHHHHHHHHHHHHHHhC------CCHHHHHHHHHHH
Confidence            333333333332211                     0000011111112334444333321      1111222222223


Q NP_000290.2     480 HNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKS  559 (747)
Q Consensus       480 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss  559 (747)
                      .++...-                                                  ......+.+.++++.|+.++. +
T Consensus       257 ~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~  285 (509)
T 4MZ6_E          257 SYLTDGP--------------------------------------------------NERIEMVVKKGVVPQLVKLLG-A  285 (509)
T ss_dssp             HHHTSSS--------------------------------------------------HHHHHHHHTTTCHHHHHHHHT-C
T ss_pred             HHHhcCC--------------------------------------------------hHHHHHHhhCChHHHHHHHhc-C
Confidence            3222100                                                  001112244567888888887 4


Q NP_000290.2     560 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVF  637 (747)
Q Consensus       560 ~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI  637 (747)
                      .++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.. +.. ..+...+++
T Consensus       286 ~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~  360 (509)
T 4MZ6_E          286 TELPIVTPALRAIGNIVTGTDE-----QTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV  360 (509)
T ss_dssp             SCHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTGGGGHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHH
T ss_pred             CCcchHHHHHHHHHHHhcCCHH-----HHHHHHhCChHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCHH
Confidence            6778888999999999875332     233334567888899999888889999999999999876 322 233445678


Q NP_000290.2     638 PEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS-QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       638 ~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~-s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      +.++.++.+      .++.++..++.+|.+++.. .+.....+.+.++++.|..++.+. ++.++..++.+|.+++.
T Consensus       361 ~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~  430 (509)
T 4MZ6_E          361 PFLVGVLSK------ADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAK-DTKIIQVILDAISNIFQ  430 (509)
T ss_dssp             HHHHHHHHS------SCHHHHHHHHHHHHHHHHHSCHHHHHHHHHTTCHHHHHHGGGCS-CHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHhcC------CCHHHHHHHHHHHHHHHcCCCHHHHHHHHhCCCHHHHHHHHhCC-CHHHHHHHHHHHHHHHH
Confidence            888888876      3678899999999999874 234444555556788888888876 78899999999999987


No 12
>5UMZ_B Importin subunit alpha-1, TNRC6A; mRNA decay, miRNA ARM repeat; HET: GOL; 1.9A {Mus musculus}
Probab=98.45  E-value=3.5e-11  Score=125.01  Aligned_cols=368  Identities=14%  Similarity=0.178  Sum_probs=227.8  Template_Neff=12.800

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAK-QQVYQLGGICKLVDLLRSPN-QNVQQAAAGALRNLVFRSTTN  321 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~-~~li~~~IL~~Ll~lL~s~d-~eVr~~AL~aLs~La~~~~~~  321 (747)
                      ..+++.+...+.+.++.++..++.++..+........ ..+...++++.+...+...+ +.++..++.++..++......
T Consensus        56 ~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~~  135 (509)
T 5UMZ_B           56 NWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQ  135 (509)
T ss_dssp             SCCHHHHHHHHTSSCHHHHHHHHHHHHHHHTSSSCCCHHHHHHTTCHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHH
T ss_pred             hhhHHHHHHHHcCCCHHHHHHHHHHHHHHHcCCCCCCHHHHHHCCcHHHHHHHhcCCCChHHHHHHHHHHHHHhCCCHHH
Confidence            4456667777777788889999999988876433211 22333456777777776543 678888999998887654433


Q NP_000290.2     322 KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVD  399 (747)
Q Consensus       322 ~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~  399 (747)
                      ...+...++++.+...+. ..++.++..++.++..++..... ...+.. ++++.|+.++.....           +..+
T Consensus       136 ~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~-----------~~~~  203 (509)
T 5UMZ_B          136 TKAVVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDL-----------STLA  203 (509)
T ss_dssp             HHHHHHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHHHTCHHHHHHHHHTTCHHHHHHHTCSSCG-----------GGSC
T ss_pred             HHHHHhcChHHHHHHHhc-CCChhHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHHhCCCh-----------hhhh
Confidence            333444467777888886 56778889999999998875432 222223 677777777764211           1122


Q NP_000290.2     400 PEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVL  479 (747)
Q Consensus       400 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  479 (747)
                      +++...+..+|..-.                     .............+++..+...+..      -+......+...|
T Consensus       204 ~~~~~~~~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l  256 (509)
T 5UMZ_B          204 CGYLRNLTWTLSNLC---------------------RNKNPAPPLDAVEQILPTLVRLLHH------NDPEVLADSCWAI  256 (509)
T ss_dssp             HHHHHHHHHHHHHHH---------------------CCCSSCCCHHHHHHHHHHHHHHTTS------SCHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHh---------------------cCCCCCCCHHHHHHHHHHHHHHHhC------CCHHHHHHHHHHH
Confidence            333333333332211                     0000011111112334444333321      1111222222223


Q NP_000290.2     480 HNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKS  559 (747)
Q Consensus       480 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss  559 (747)
                      .++...-                                                  ......+.+.++++.|+.++. +
T Consensus       257 ~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~  285 (509)
T 5UMZ_B          257 SYLTDGP--------------------------------------------------NERIEMVVKKGVVPQLVKLLG-A  285 (509)
T ss_dssp             HHHTSSC--------------------------------------------------HHHHHHHHTTTCHHHHHHHHT-C
T ss_pred             HHHhcCC--------------------------------------------------hHHHHHHhhCChHHHHHHHhc-C
Confidence            3222100                                                  001112244567888888887 4


Q NP_000290.2     560 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVF  637 (747)
Q Consensus       560 ~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI  637 (747)
                      .++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.. +.. ..+...+++
T Consensus       286 ~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~  360 (509)
T 5UMZ_B          286 TELPIVTPALRAIGNIVTGTDE-----QTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV  360 (509)
T ss_dssp             SCHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTGGGGHHHHTTCSSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHH
T ss_pred             CCcchHHHHHHHHHHHhcCCHH-----HHHHHHhCChHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCHH
Confidence            6778888999999999875332     233334567888899999888889999999999999876 322 233445678


Q NP_000290.2     638 PEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS-QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       638 ~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~-s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      +.++.++.+      .++.++..++.+|.+++.. .+.....+.+.++++.|..++.+. ++.++..++.+|.+++.
T Consensus       361 ~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~  430 (509)
T 5UMZ_B          361 PFLVGVLSK------ADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAK-DTKIIQVILDAISNIFQ  430 (509)
T ss_dssp             HHHHHHHHS------SCHHHHHHHHHHHHHHHHHSCHHHHHHHHHTTCHHHHHHGGGCS-CHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHhcC------CCHHHHHHHHHHHHHHHcCCCHHHHHHHHhCCCHHHHHHHHhCC-CHHHHHHHHHHHHHHHH
Confidence            888888876      3678899999999999874 234444555556788888888876 78899999999999987


No 13
>2JDQ_A IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC; TRANSPORT, PB2 SUBUNIT, NUCLEAR PROTEIN; 2.2A {HOMO SAPIENS}
Probab=98.45  E-value=3.6e-11  Score=122.13  Aligned_cols=367  Identities=14%  Similarity=0.163  Sum_probs=226.8  Template_Neff=13.000

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESA--KQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTT  320 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~--~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~  320 (747)
                      +.+++.+...+.+.++.++..++.+|..+.......  ...+...++++.+...+.. .++.++..++.++..++.....
T Consensus        19 ~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~   98 (450)
T 2JDQ_A           19 GVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSL   98 (450)
T ss_dssp             ---CHHHHHHHHSSCHHHHHHHHHHHHHHHHSSSSCCHHHHHTSTTHHHHHHHHHTCTTCHHHHHHHHHHHHHHHSSCHH
T ss_pred             CcccHHHHHHHhcCCHHHHHHHHHHHHHHHccCCCCCHhHHhcCcchHHHHHHHHccCCCHHHHHHHHHHHHHHhCCCcH
Confidence            445567777788788889999999999887532211  1222224667777777765 5677888899999888765443


Q NP_000290.2     321 NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVV  398 (747)
Q Consensus       321 ~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~  398 (747)
                      ....+...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.++.++...               .
T Consensus        99 ~~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~  162 (450)
T 2JDQ_A           99 QTRIVIQAGAVPIFIELLS-SEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ---------------N  162 (450)
T ss_dssp             HHHHHHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHHTTSC---------------C
T ss_pred             HHHHHHHcChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCChHHHHHHHHCCCHHHHHHHHhhc---------------c
Confidence            3333333467777888876 5567888899999998887543 2223333 6777777776431               1


Q NP_000290.2     399 DPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCV  478 (747)
Q Consensus       399 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  478 (747)
                      ++++...+..++..-..                     ............+++..+...+..      -+..-...+...
T Consensus       163 ~~~~~~~a~~~l~~l~~---------------------~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~  215 (450)
T 2JDQ_A          163 RLTMTRNAVWALSNLCR---------------------GKSPPPEFAKVSPCLNVLSWLLFV------SDTDVLADACWA  215 (450)
T ss_dssp             CHHHHHHHHHHHHHHHC---------------------CSSSCCCGGGTGGGHHHHHHHTTC------CCHHHHHHHHHH
T ss_pred             chhHHHHHHHHHHHHhc---------------------CCCCCchhhhhhhHHHHHHHHhcC------CCHHHHHHHHHH
Confidence            23443344333322110                     000111111222333333332221      111122222223


Q NP_000290.2     479 LHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK  558 (747)
Q Consensus       479 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s  558 (747)
                      |.++...-                                                  ......+.+.++++.++.++. 
T Consensus       216 l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-  244 (450)
T 2JDQ_A          216 LSYLSDGP--------------------------------------------------NDKIQAVIDAGVCRRLVELLM-  244 (450)
T ss_dssp             HHHHTSSS--------------------------------------------------HHHHHHHHHTTTHHHHHHHTT-
T ss_pred             HHHHhcCC--------------------------------------------------HHHHHHHHHCCHHHHHHHHHc-
Confidence            33222110                                                  001112245567888888887 


Q NP_000290.2     559 SKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQV  636 (747)
Q Consensus       559 s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~gi  636 (747)
                      +.++.++..++.+|.+++...+.     ....+.+.++++.+..++.+.++.++..++.+|.+++... .. ......++
T Consensus       245 ~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~  319 (450)
T 2JDQ_A          245 HNDYKVVSPALRAVGNIVTGDDI-----QTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANI  319 (450)
T ss_dssp             CSCHHHHHHHHHHHHHHTTSCHH-----HHHHHHTTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTH
T ss_pred             CCCHHHHHHHHHHHHHHhhCChH-----HHHHHhhcchHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHhCCH
Confidence            46778888999999999875332     2233345578888999998888889999999999998762 22 23344567


Q NP_000290.2     637 FPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQ-PQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       637 I~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s-~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ++.+..++.+      .++.++..++.+|.+++... +.....+.+.++++.+..++.+. ++.++..++.+|.+++...
T Consensus       320 ~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~~~  392 (450)
T 2JDQ_A          320 FPALISILQT------AEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVM-DSKIVQVALNGLENILRLG  392 (450)
T ss_dssp             HHHHHHHHHH------SCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHTCHHHHHHGGGSS-CHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHhc------CCHHHHHHHHHHHHHHhcCCCHHHHHHHHHCCcHHHHHHHhhCC-CHHHHHHHHHHHHHHHHHh
Confidence            8888888876      36788899999999998752 34445555556788888888876 7889999999999998765


Q NP_000290.2     716 E  716 (747)
Q Consensus       716 ~  716 (747)
                      +
T Consensus       393 ~  393 (450)
T 2JDQ_A          393 E  393 (450)
T ss_dssp             H
T ss_pred             H
Confidence            4


No 14
>4E4V_A Importin subunit alpha-2; armadillo repeat, karyopherin, importin, nuclear; HET: GOL, DTT; 2.5283A {Homo sapiens}
Probab=98.45  E-value=3.6e-11  Score=124.32  Aligned_cols=364  Identities=17%  Similarity=0.189  Sum_probs=218.6  Template_Neff=12.700

Q NP_000290.2     246 TIPKAVQYLSSQD-EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd-~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+.+ +.++..++.++..++.........+...++++.+..++.+.++.++..++.++..++.........
T Consensus        76 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  155 (485)
T 4E4V_A           76 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDL  155 (485)
T ss_dssp             CHHHHHHHTTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHHTTCHHHHHH
T ss_pred             cHHHHHHHhcCCCChHHHHHHHHHHHHHhcCChHHHHHHHhcChHHHHHHHhcCCChhHHHHHHHHHHHHhcCCHHHHHH
Confidence            4555666665443 678888889988887654433334444567778888888777888999999999888654432333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNA-----EIQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~-----eVr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      +...++++.+...+. ....     .++..++.++..++..........  .++++.+..++..                
T Consensus       156 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------  218 (485)
T 4E4V_A          156 VIKYGAVDPLLALLA-VPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHH----------------  218 (485)
T ss_dssp             HHHTTCHHHHHHTTC-SSCGGGSCHHHHHHHHHHHHHHTCCCSSCCCHHHHHHHHHHHHHHTTS----------------
T ss_pred             HHHCCcHHHHHHHHh-CCCcccchHHHHHHHHHHHHHHHhCCCCCCCHHHHhcHHHHHHHHhcC----------------
Confidence            333456666776665 2222     567778888888876443222222  2556666666542                


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                      .|+++...+..+|..-..                     .+......---.+++..|...+..      .+..-...+..
T Consensus       219 ~~~~~~~~a~~~l~~l~~---------------------~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~  271 (485)
T 4E4V_A          219 DDPEVLADTCWAISYLTD---------------------GPNERIGMVVKTGVVPQLVKLLGA------SELPIVTPALR  271 (485)
T ss_dssp             CCHHHHHHHHHHHHHHTS---------------------SCHHHHHHHHTTTCHHHHHHHHTC------SCHHHHHHHHH
T ss_pred             CCHHHHHHHHHHHHHHhc---------------------CChHHhhHHhhCChHHHHHHHhcC------CChHHHHHHHH
Confidence            134444444444432110                     000000000012233333333221      11222223333


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      +|.++...-                                                  ......+.+.++++.|+.++.
T Consensus       272 ~l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~  301 (485)
T 4E4V_A          272 AIGNIVTGT--------------------------------------------------DEQTQVVIDAGALAVFPSLLT  301 (485)
T ss_dssp             HHHHHTTSC--------------------------------------------------HHHHHHHHHTTGGGGHHHHHT
T ss_pred             HHHHHhcCC--------------------------------------------------HHHHHHHHhCChHHHHHHHhc
Confidence            333332100                                                  001112234567888888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGN  634 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~  634 (747)
                       +.++.++..++.+|.+++...+.     ....+...++++.|+.++.+.++.++..++.+|.+++.. . .. ..+...
T Consensus       302 -~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~  375 (485)
T 4E4V_A          302 -NPKTNIQKEATWTMSNITAGRQD-----QIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHC  375 (485)
T ss_dssp             -CSSHHHHHHHHHHHHHHHTSCHH-----HHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHSCHHHHHHHHHT
T ss_pred             -CCCHHHHHHHHHHHHHHcCCCHH-----HHHHHHHCCHHHHHHHHHhcCCHHHHHHHHHHHHHHHhcCCHHHHHHHHhC
Confidence             46778888999999999875332     233334557888899999888888999999999999875 2 12 233445


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQ------PQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s------~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      ++++.+..++.+      .++.++..++.+|.+++...      +.....+.+.++++.|..++.+. ++.++..++.+|
T Consensus       376 ~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l  448 (485)
T 4E4V_A          376 GIIEPLMNLLTA------KDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHE-NESVYRASLSLI  448 (485)
T ss_dssp             TCHHHHHHGGGC------SCHHHHHHHHHHHHHHHHHHHHTTCHHHHHHHHHHTTHHHHHHTTCCTT-SHHHHHHHHHHH
T ss_pred             CcHHHHHHHhhc------CCHHHHHHHHHHHHHHHHHHHHhCChhHHHHHHHHcCHHHHHHHHHhCC-CHHHHHHHHHHH
Confidence            677888888776      36788999999999998731      22333344456788888888766 788999999999


Q NP_000290.2     709 SDMWSSKE  716 (747)
Q Consensus       709 snL~~~~~  716 (747)
                      .+++...+
T Consensus       449 ~~l~~~~~  456 (485)
T 4E4V_A          449 EKYFSVEE  456 (485)
T ss_dssp             HHHCC---
T ss_pred             HHHcCccc
Confidence            99986543


No 15
>4B18_A IMPORTIN SUBUNIT ALPHA-1, TELOMERASE REVERSE; TRANSPORT PROTEIN - PEPTIDE COMPLEX; 2.52A {HOMO SAPIENS}
Probab=98.44  E-value=4e-11  Score=121.64  Aligned_cols=368  Identities=14%  Similarity=0.162  Sum_probs=227.4  Template_Neff=13.000

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES--AKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTT  320 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~--~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~  320 (747)
                      +.+++.+...+.+.++.++..++.+|..+......  ....+...++++.+...+.. .++.++..++.++..++.....
T Consensus        16 ~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~   95 (447)
T 4B18_A           16 GVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSL   95 (447)
T ss_dssp             CSSCHHHHHHHTSSCHHHHHHHHHHHHHHHHCSSCCCHHHHHTSTTHHHHHHHHTTCTTCHHHHHHHHHHHHHHTSSCHH
T ss_pred             CCCcHHHHHHHhcCCHHHHHHHHHHHHHHhCCCCCCCHhHHhcCccHHHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCcH
Confidence            44556677777777888899999999888753221  11222224667777777765 5677888899999888765433


Q NP_000290.2     321 NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVV  398 (747)
Q Consensus       321 ~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~  398 (747)
                      ....+...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.|+.++...               .
T Consensus        96 ~~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~  159 (447)
T 4B18_A           96 QTRIVIQAGAVPIFIELLS-SEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ---------------N  159 (447)
T ss_dssp             HHHHHHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHGGGCT---------------T
T ss_pred             HHHHHHHcChHHHHHHHhh-CCCHHHHHHHHHHHHHHHccChhHHHHHHHCCcHHHHHHHhhcC---------------C
Confidence            3223333467777888776 5567888899999998887543 2223333 6677777766431               1


Q NP_000290.2     399 DPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCV  478 (747)
Q Consensus       399 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  478 (747)
                      ++++...+..+|..-.                     .............+++..+...++.      -+......+...
T Consensus       160 ~~~~~~~~~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~  212 (447)
T 4B18_A          160 RLTMTRNAVWALSNLC---------------------RGKSPPPEFAKVSPCLNVLSWLLFV------SDTDVLADACWA  212 (447)
T ss_dssp             CHHHHHHHHHHHHHHH---------------------CCSSSCCCHHHHGGGHHHHHHHTTS------CCHHHHHHHHHH
T ss_pred             ChhHHHHHHHHHHHHh---------------------cCCCCCCcccccccHHHHHHHHhhC------CCHHHHHHHHHH
Confidence            2344333333332211                     0000111111122333333322211      111112222222


Q NP_000290.2     479 LHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK  558 (747)
Q Consensus       479 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s  558 (747)
                      |.++...-                                                  ......+.+.++++.++.++. 
T Consensus       213 l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-  241 (447)
T 4B18_A          213 LSYLSDGP--------------------------------------------------NDKIQAVIDAGVCRRLVELLM-  241 (447)
T ss_dssp             HHHHTSSS--------------------------------------------------HHHHHHHHHTTCHHHHHHHTT-
T ss_pred             HHHHhcCC--------------------------------------------------HHHHHHHHHCCHHHHHHHHHc-
Confidence            32222100                                                  001112245567888888887 


Q NP_000290.2     559 SKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQV  636 (747)
Q Consensus       559 s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~gi  636 (747)
                      +.++.++..++.+|.+++...+.     ....+.+.++++.|..++.+.++.++..++.+|.+++... .. ......++
T Consensus       242 ~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~  316 (447)
T 4B18_A          242 HNDYKVVSPALRAVGNIVTGDDI-----QTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANI  316 (447)
T ss_dssp             CSCHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTH
T ss_pred             CCCHHHHHHHHHHHHHHhcCChH-----HHHHHhhcchHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHhCCh
Confidence            46778888999999999875332     2233345578888999998888889999999999998762 22 23344567


Q NP_000290.2     637 FPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS-QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       637 I~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~-s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ++.+..++.+      .++.++..++.+|.+++.. .+.....+.+.++++.+..++.+. ++.++..++.+|.+++...
T Consensus       317 ~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~~~  389 (447)
T 4B18_A          317 FPALISILQT------AEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVM-DSKIVQVALNGLENILRLG  389 (447)
T ss_dssp             HHHHHHHHHH------SCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHTCHHHHHHGGGSS-CHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHhc------CCHHHHHHHHHHHHHHhccCCHHHHHHHHHCCcHHHHHHHhhCC-CHHHHHHHHHHHHHHHHHh
Confidence            8888888876      3678899999999999875 234445555556788888888876 7889999999999998765


Q NP_000290.2     716 EL  717 (747)
Q Consensus       716 ~~  717 (747)
                      +.
T Consensus       390 ~~  391 (447)
T 4B18_A          390 EQ  391 (447)
T ss_dssp             HH
T ss_pred             HH
Confidence            43


No 16
>4XZR_B Heh1-NLS, Kap60; karyopherins  nuclear import ; 2.25A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=98.43  E-value=4.3e-11  Score=119.82  Aligned_cols=363  Identities=16%  Similarity=0.214  Sum_probs=223.0  Template_Neff=13.200

Q NP_000290.2     248 PKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLRSPN-QNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       248 ~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~s~d-~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +.+...+.+.++.++..++..+..++..... ........++++.+...+...+ +.++..++.++..++.........+
T Consensus         4 ~~l~~~l~~~~~~~~~~a~~~l~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~~~~~~   83 (423)
T 4XZR_B            4 PQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVV   83 (423)
T ss_dssp             SSSSTTTSSSCHHHHHHHHHHHHHHHSCSSSCCHHHHHTTTCHHHHHHTTSTTSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             hhHhhhcChHhHHHHHHHHHHHHHHHcCCCCCchHHHHhCCcHHHHHHHhhCCCCHHHHHHHHHHHHHHhCCCchhhhHH
Confidence            4455566667777888888888877654321 1222333466777777776543 6778889999988876543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ...++++.+...+. +.++.++..++.++..++... .....+.. ++++.|..++...                ++++.
T Consensus        84 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~v~  146 (423)
T 4XZR_B           84 VDADAVPLFIQLLY-TGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSN----------------KPSLI  146 (423)
T ss_dssp             HHTTCHHHHHHHHH-HSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHHTTSC----------------CHHHH
T ss_pred             cccchHHHHHHHHh-CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCcHHHHHHHHhcC----------------CHHHH
Confidence            33467777777776 567788899999999988753 22233333 6677777766521                34444


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-..                     .........-..+.++.|...++.      .+......+...|.++.
T Consensus       147 ~~a~~~l~~l~~---------------------~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~  199 (423)
T 4XZR_B          147 RTATWTLSNLCR---------------------GKKPQPDWSVVSQALPTLAKLIYS------MDTETLVDACWAISYLS  199 (423)
T ss_dssp             HHHHHHHHHHHC---------------------CCTTCCCHHHHGGGHHHHHHHTTC------SCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHHc---------------------CCCCCCChHHhccHHHHHHHHhhC------CCHHHHHHHHHHHHHHh
Confidence            444444432111                     000001111122334444333321      11112222222333322


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ..                                                  +......+.+.++++.++.++. +.++.
T Consensus       200 ~~--------------------------------------------------~~~~~~~~~~~~~~~~l~~~l~-~~~~~  228 (423)
T 4XZR_B          200 DG--------------------------------------------------PQEAIQAVIDVRIPKRLVELLS-HESTL  228 (423)
T ss_dssp             SS--------------------------------------------------SHHHHHHHHHTTHHHHHHHHTT-CSCHH
T ss_pred             cC--------------------------------------------------CHHHHHHHHhcCHHHHHHHHhc-CCCHH
Confidence            11                                                  0011122345567888888887 46778


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVFPEVT  641 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI~~Ll  641 (747)
                      ++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++... .. ..+...++++.+.
T Consensus       229 ~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~  303 (423)
T 4XZR_B          229 VQTPALRAVGNIVTGNDL-----QTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLV  303 (423)
T ss_dssp             HHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHH
T ss_pred             HHHHHHHHHHHHHcCCHH-----HHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHH
Confidence            888999999999865332     2223334578888888888888889999999999998762 22 3334556778888


Q NP_000290.2     642 RLLTSHTGNTSNSEDILSSACYTVRNLMASQP---QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKEL  717 (747)
Q Consensus       642 ~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~---e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~~  717 (747)
                      .++.+      .++.++..++.+|.+++....   .....+.+.++++.+..++.+. ++.++..++.+|.+++...+.
T Consensus       304 ~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~l~~l~~~~~~  375 (423)
T 4XZR_B          304 KLLEV------AEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIA-DNRIIEVTLDALENILKMGEA  375 (423)
T ss_dssp             HHHHH------SCHHHHHHHHHHHHHHHHGGGTCHHHHHHHHHTTCHHHHHHHTTTS-CHHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHh------CCchHHHHHHHHHHHHHhCCCCCHHHHHHHHHCCcHHHHHHHhhcC-CHHHHHHHHHHHHHHHHHHHH
Confidence            88866      367889999999999987532   2234445556788888888876 788899999999999876554


No 17
>5XZX_A Importin subunit alpha-3, Ran-binding protein; nuclear import, TRANSPORT PROTEIN; 3.0A {Homo sapiens}
Probab=98.43  E-value=4.3e-11  Score=119.52  Aligned_cols=133  Identities=19%  Similarity=0.169  Sum_probs=87.0  Template_Neff=13.200

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      ++.+...+.+.++.++..++.+|..+...... ....+...++++.+...+. ..++.++..++.++..++.........
T Consensus         4 ~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~   83 (416)
T 5XZX_A            4 LEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQA   83 (416)
T ss_dssp             HHHHHHHTTCSSHHHHHHHHHHHHHTTSSSSSCCHHHHHTTTCHHHHHHHTTCTTCHHHHHHHHHHHHHHHTSCHHHHHH
T ss_pred             HHHHHHHHhcCCHHHHHHHHHHHHHHHhCCCCCCHHHHHHcCcHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCChHHHHH
Confidence            44566666677778888999999888764321 1122333456777777776 456778888899998887654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~  380 (747)
                      +...++++.+...+. +.++.++..++.++..++... .....+.. ++++.|..++.
T Consensus        84 ~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  140 (416)
T 5XZX_A           84 VVQSNAVPLFLRLLH-SPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFIS  140 (416)
T ss_dssp             HHHTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHHTTCHHHHHHHHHHTCHHHHTTSCS
T ss_pred             HHhcChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCccHHHHHHhcC
Confidence            334457777777776 567788899999999988652 22222333 66677776664


No 18
>1JDH_A BETA-CATENIN, hTcf-4; BETA-CATENIN, TCF4, PROTEIN-PROTEIN COMPLEX, TRANSCRIPTION; 1.9A {Homo sapiens} SCOP: a.118.1.1
Probab=98.42  E-value=4.4e-11  Score=123.86  Aligned_cols=378  Identities=19%  Similarity=0.226  Sum_probs=227.0  Template_Neff=13.100

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..++.........+...++++.+...+.+.++.++..++.++..++.........
T Consensus       101 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  180 (529)
T 1JDH_A          101 GGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLI  180 (529)
T ss_dssp             THHHHHHHHTTCSCHHHHHHHHHHHHHHHHHCTTHHHHHHHHTHHHHHHHGGGCCCHHHHHHHHHHHHHHHTTCHHHHHH
T ss_pred             CCHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCcchHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHH
Confidence            34556666666667788888999998887654333333334567777888887777888899999999888544433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      +...++++.+...+....+..++..++.++..+.........+.. ++++.+..++...                ++++.
T Consensus       181 ~~~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~~  244 (529)
T 1JDH_A          181 ILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDP----------------SQRLV  244 (529)
T ss_dssp             HHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTSTTHHHHHHHTTHHHHHHTTTTSS----------------CHHHH
T ss_pred             HHHCChhHHHHHHHccCCcHHHHHHHHHHHHHHhcCCccHHHHHHCCHHHHHHHHccCC----------------CHHHH
Confidence            444457777777776333567888888888888875443333333 6667776666432                23333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-.                     ........+   .+++..+...++.      -+..-...+...|.++.
T Consensus       245 ~~~~~~l~~l~---------------------~~~~~~~~~---~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  294 (529)
T 1JDH_A          245 QNCLWTLRNLS---------------------DAATKQEGM---EGLLGTLVQLLGS------DDINVVTCAAGILSNLT  294 (529)
T ss_dssp             HHHHHHHHHHH---------------------TTCTTCSCC---HHHHHHHHHHTTC------SCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHc---------------------chhhhHHHH---chHHHHHHHHhCC------CCHHHHHHHHHHHHHHh
Confidence            33333332110                     000000001   2334444333321      11111222223333332


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK-SKKD  562 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s-s~d~  562 (747)
                      ...                                                  ......+.+.++++.++..+.. ..++
T Consensus       295 ~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~~~~~~~  324 (529)
T 1JDH_A          295 CNN--------------------------------------------------YKNKMMVCQVGGIEALVRTVLRAGDRE  324 (529)
T ss_dssp             TTC--------------------------------------------------HHHHHHHHHTTHHHHHHHHHHHHTTCH
T ss_pred             cCC--------------------------------------------------HHHHHHHHHcCHHHHHHHHHHhcCCCh
Confidence            110                                                  0001112345667777776641 2456


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEV  640 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~L  640 (747)
                      .++..++.+|.+++.....  .......+...++++.+..++.+. ++.++..++.+|.+++..... ..+...++++.+
T Consensus       325 ~~~~~a~~~l~~l~~~~~~--~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l  402 (529)
T 1JDH_A          325 DITEPAICALRHLTSRHQE--AEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRL  402 (529)
T ss_dssp             HHHHHHHHHHHHHTSSSTT--HHHHHHHHHHTTCHHHHHHTTSTTCCHHHHHHHHHHHHHHTTSGGGHHHHHHTTHHHHH
T ss_pred             HhHHHHHHHHHHHhcCccc--HHHHHHHHHhcccHHHHHHHHCCCCCHHHHHHHHHHHHHHhcChhhhHHHHhcCHHHHH
Confidence            7788899999998865331  000012222456788888888765 678899999999999876433 334455677888


Q NP_000290.2     641 TRLLTSHTGNTSNS--------------------EDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       641 l~LL~s~s~~~~~d--------------------~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      ..++....    .+                    +.++..++.+|.+++.. ......+...++++.++.++.+. ++.+
T Consensus       403 ~~~l~~~~----~~~~~~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~l~~~-~~~~~~~~~~~~~~~l~~~l~~~-~~~~  476 (529)
T 1JDH_A          403 VQLLVRAH----QDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARD-VHNRIVIRGLNTIPLFVQLLYSP-IENI  476 (529)
T ss_dssp             HHHHHHHH----HHHC-----------CBTTBCHHHHHHHHHHHHHHHTTS-HHHHHHHHHTTCHHHHHHGGGCS-CHHH
T ss_pred             HHHHHhcC----hhHHHHHhccCcchhHhccCCHHHHHHHHHHHHHHHhcC-ccchHHHHhcCcHHHHHHHhcCC-CHHH
Confidence            88876520    01                    67888999999999875 34444455556788888888876 7889


Q NP_000290.2     701 AEAARLLLSDMWSSKELQGVLRQQGF  726 (747)
Q Consensus       701 r~aAL~aLsnL~~~~~~~~~~~~~~~  726 (747)
                      +..++.+|.+++...+....+...|+
T Consensus       477 ~~~a~~~l~~l~~~~~~~~~~~~~~~  502 (529)
T 1JDH_A          477 QRVAAGVLCELAQDKEAAEAIEAEGA  502 (529)
T ss_dssp             HHHHHHHHHHHTTSHHHHHHHHHTTC
T ss_pred             HHHHHHHHHHHhcCHHHHHHHHHcCc
Confidence            99999999999987765544444443


No 19
>3IFQ_A plakoglobin, E-cadherin; armadillo repeat, Cardiomyopathy, Cell adhesion; HET: SO4; 2.8A {Homo sapiens}
Probab=98.42  E-value=4.5e-11  Score=124.53  Aligned_cols=381  Identities=19%  Similarity=0.234  Sum_probs=227.1  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++..++.........+...++++.+...+.+.++.++..++.++..++.........+
T Consensus       104 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  183 (553)
T 3IFQ_A          104 GIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLII  183 (553)
T ss_dssp             HHHHHHHGGGCCCHHHHHHHHHHHHHHHHHCTTHHHHHHHTTGGGGTGGGGGSSCHHHHHHHHHHHHHHHTTCHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHhcCChHHHHHHHhcCHHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666677888889999988876543333333335677788888877778888999999998876444333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFF  404 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~  404 (747)
                      ...++++.+...+....+..++..++.++..+.........+.. ++++.+..++...                ++++..
T Consensus       184 ~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~~~  247 (553)
T 3IFQ_A          184 LANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSN----------------SPRLVQ  247 (553)
T ss_dssp             HHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTSTTHHHHHHHTTHHHHHHGGGGSS----------------CHHHHH
T ss_pred             HHCCHHHHHHHHHhcCCcHHHHHHHHHHHHHHhCCcchHHHHHHCchHHHHHHHHhcC----------------CHHHHH
Confidence            34456777777776333567888888888888775444333443 6667777666531                233333


Q NP_000290.2     405 NATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSY  484 (747)
Q Consensus       405 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  484 (747)
                      .+..++..-..                     ......   ...++++.+...++.      .+..-...+...|.++..
T Consensus       248 ~a~~~l~~l~~---------------------~~~~~~---~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~  297 (553)
T 3IFQ_A          248 NCLWTLRNLSD---------------------VATKQE---GLESVLKILVNQLSV------DDVNVLTCATGTLSNLTC  297 (553)
T ss_dssp             HHHHHHHHHHT---------------------TCTTCS---CCHHHHHHHHTTTTC------CCHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHhCC---------------------hhHHHH---HHHHHHHHHHHHcCC------CCHHHHHHHHHHHHHHHc
Confidence            33333322110                     000011   112344444433321      111222233333333321


Q NP_000290.2     485 RLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK-SKKDA  563 (747)
Q Consensus       485 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s-s~d~e  563 (747)
                      ...                                                  .....+.+.++++.++..+.. ..++.
T Consensus       298 ~~~--------------------------------------------------~~~~~~~~~~~~~~l~~~l~~~~~~~~  327 (553)
T 3IFQ_A          298 NNS--------------------------------------------------KNKTLVTQNSGVEALIHAILRAGDKDD  327 (553)
T ss_dssp             TCH--------------------------------------------------HHHHHHTTTTHHHHHHHHHHHHTTCHH
T ss_pred             CCH--------------------------------------------------HHHHHHHHccHHHHHHHHHHHcCCChH
Confidence            100                                                  001122345677777776652 14566


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN-SDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVT  641 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d-~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll  641 (747)
                      ++..++.+|.+++..... ... ....+...++++.+..++.+.+ +.++..++.+|.+++..... ......++++.+.
T Consensus       328 ~~~~a~~~l~~l~~~~~~-~~~-~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~  405 (553)
T 3IFQ_A          328 ITEPAVCALRHLTSRHPE-AEM-AQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLV  405 (553)
T ss_dssp             HHHHHHHHHHHHTSSSTT-HHH-HHHHHHTTTHHHHHHHGGGCTTCHHHHHHHHHHHHHHTTSGGGHHHHHHTTHHHHHH
T ss_pred             hHHHHHHHHHHHhcCCCh-HHH-HHHHHHHcchHHHHHHHHcCCCChHHHHHHHHHHHHHhcCcccHHHHHHccHHHHHH
Confidence            788889999998865321 000 0112234567888888887654 78889999999999876433 2334456778888


Q NP_000290.2     642 RLLTSHTGN---------------TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       642 ~LL~s~s~~---------------~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      .++......               ......++..++.+|.+++.. +.....+...++++.++.++.+. ++.++..++.
T Consensus       406 ~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~-~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~  483 (553)
T 3IFQ_A          406 QLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCTGALHILARD-PMNRMEIFRLNTIPLFVQLLYSS-VENIQRVAAG  483 (553)
T ss_dssp             HHHHHHHHHHHHHHHTTCCCTTCSSCCHHHHHHHHHHHHHHHTTS-HHHHHHHHHTTCHHHHHHHTTCS-CHHHHHHHHH
T ss_pred             HHHHHcCcchhHHHhhcccCccccCCCHHHHHHHHHHHHHHHhcC-hhhHHHHHHcCChHHHHHHHhCC-CHHHHHHHHH
Confidence            877652100               000027788899999999874 44445555667888888888866 7889999999


Q NP_000290.2     707 LLSDMWSSKELQGVLRQQGF  726 (747)
Q Consensus       707 aLsnL~~~~~~~~~~~~~~~  726 (747)
                      +|.+++...+....+.+.|.
T Consensus       484 ~l~~l~~~~~~~~~~~~~~~  503 (553)
T 3IFQ_A          484 VLCELAQDKEAADAIDAEGA  503 (553)
T ss_dssp             HHHHHTTSHHHHHHHHHTTT
T ss_pred             HHHHHHcCHHHHHHHHHCCc
Confidence            99999987766555554443


No 20
>4UAD_A Importin alpha import adaptor, Influenza; importin karyopherin complex NLS, PROTEIN; 2.42A {Homo sapiens}
Probab=98.39  E-value=6e-11  Score=121.78  Aligned_cols=372  Identities=17%  Similarity=0.175  Sum_probs=218.3  Template_Neff=12.900

Q NP_000290.2     246 TIPKAVQYLSS-QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~s-sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+ .++.++..++.++..++.........+...++++.+..++.+.+..++..++.++..++.........
T Consensus        68 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  147 (479)
T 4UAD_A           68 VVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRDY  147 (479)
T ss_dssp             HHHHHHHHTTCTTCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHHTSCHHHHHH
T ss_pred             hHHHHHHHhhcCCCHHHHHHHHHHHHHHhCCCchHHHHHHHcCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHHH
Confidence            45556666654 56778888899998887654333333333567777888887777888899999999887654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELI-A-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lv-e-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...+++..+...+....++.++..++.++..++.......... . ++++.++.++...                ++++
T Consensus       148 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~  211 (479)
T 4UAD_A          148 VLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSS----------------DSDL  211 (479)
T ss_dssp             HHHTTCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCSSCCCGGGTGGGHHHHHHHTTCC----------------CHHH
T ss_pred             HHhCCcHHHHHHHhhcCCchHHHHHHHHHHHHHHcCCCCCchhhcccchHHHHHHHhcCC----------------CHHH
Confidence            33345666677766533456788888888888876542222222 1 5666666666431                2333


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      -..+..++..-...      .+              ...+.+ .-.+.+..|...++.      .+..-...+...|.++
T Consensus       212 ~~~a~~~l~~l~~~------~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l  264 (479)
T 4UAD_A          212 LADACWALSYLSDG------PN--------------EKIQAV-IDSGVCRRLVELLMH------NDYKVASPALRAVGNI  264 (479)
T ss_dssp             HHHHHHHHHHHTSS------SH--------------HHHHHH-HHTTCHHHHHHGGGC------SCHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhcC------ch--------------HHHHHH-HhCCHHHHHHHHhcC------CCHHhHHHHHHHHHHH
Confidence            33333333221100      00              000000 012333333333221      0111111222222222


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ....                                                  ......+.+.++++.|+.++. +.++
T Consensus       265 ~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~  293 (479)
T 4UAD_A          265 VTGD--------------------------------------------------DIQTQVILNCSALPCLLHLLS-SPKE  293 (479)
T ss_dssp             TTSC--------------------------------------------------HHHHHHHHTTTCHHHHHHHTT-CSSH
T ss_pred             hcCC--------------------------------------------------HHHHHHHHhcChHHHHHHHhh-CCCH
Confidence            2100                                                  000112234567888888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH--PLL-HRVMGNQVFPE  639 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~--~e~-~~ll~~giI~~  639 (747)
                      .++..++.+|.+++...+.     ....+.+.++++.|..++.+.++.++..++.+|.+++..  ... ..+...++++.
T Consensus       294 ~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~  368 (479)
T 4UAD_A          294 SIRKEACWTISNITAGNRA-----QIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKP  368 (479)
T ss_dssp             HHHHHHHHHHHHHTTSCHH-----HHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHSCHHHHHHHHHTTCHHH
T ss_pred             HHHHHHHHHHHHHHcCCHH-----HHHHHHHCCHHHHHHHHHhccCHHHHHHHHHHHHHHHcCCCHHHHHHHHHcCcHHH
Confidence            8888999999999865332     223334557888999999888889999999999999874  222 23344567788


Q NP_000290.2     640 VTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQ-----------YFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       640 Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~-----------Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      +..++.+      .++.++..++.+|.+++...+.....           +.+.+.++.+..++.+. ++.++..++.+|
T Consensus       369 l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~~-~~~v~~~a~~~l  441 (479)
T 4UAD_A          369 LCDLLTV------MDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQSHE-NQEIYQKAFDLI  441 (479)
T ss_dssp             HHGGGGC------SCHHHHHHHHHHHHHHHHHHHHHTTTTSCCCCTTHHHHHHTTHHHHHHHGGGCS-CHHHHHHHHHHH
T ss_pred             HHHHhhc------CCHHHHHHHHHHHHHHHHHHHHhcccCCCCcCHHHHHHHHhchHHHHHHHHhCC-cHHHHHHHHHHH
Confidence            8888776      36788889999999998753322111           34445677888888766 788999999999


Q NP_000290.2     709 SDMWSSKELQGVLRQ  723 (747)
Q Consensus       709 snL~~~~~~~~~~~~  723 (747)
                      .+++...+....+.+
T Consensus       442 ~~l~~~~~~~~~~~~  456 (479)
T 4UAD_A          442 EHYFGVEDDDSSLAP  456 (479)
T ss_dssp             HHHSCC---------
T ss_pred             HHhhCCCCCchhccc
Confidence            999977665554443


No 21
>5ZHX_D Rap1 GTPase-GDP dissociation stimulator 1; armadillo GEF chaperone, ONCOPROTEIN; HET: FAR; 3.5A {Homo sapiens}
Probab=98.39  E-value=6.3e-11  Score=120.93  Aligned_cols=407  Identities=17%  Similarity=0.217  Sum_probs=228.2  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP--NQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~--d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      +++.+...+.+.++.++..++.++..++...+.....+...++++.+..++...  ++.++..++.++..++.... ...
T Consensus        19 ~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~v~~~a~~~l~~l~~~~~-~~~   97 (487)
T 5ZHX_D           19 LISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELES-SKE   97 (487)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHTTSTTCHHHHHHHHHTTCHHHHHHHHHHTSSCSHHHHHHHHHHHHHTTSSH-HHH
T ss_pred             cHHHHHHHHcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHHcccCCCHHHHHHHHHHHHHHHcchh-HHH
Confidence            556677777777888999999999998875544444444556778888888765  77888899999998876532 222


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      .+...++++.+...+....++.++..++.++..++........+.. ++++.|..++.......         .....+.
T Consensus        98 ~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~---------~~~~~~~  168 (487)
T 5ZHX_D           98 QFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSD---------KEDDITE  168 (487)
T ss_dssp             HHHHTTHHHHHHHHHHHCCSHHHHHHHHHHHHHHHTSHHHHHHHHHHTHHHHHHHHHHHTSSCC---------CHHHHHH
T ss_pred             HHhhCCHHHHHHHHHHhccChHHHHHHHHHHHHHhcCHHHHHHHHHCCHHHHHHHHHHhcCCCC---------CHHHHHH
Confidence            3334467777888776222677888899999998876444444444 67777777776432100         0000000


Q NP_000290.2     403 FFNATGCLR----------KRL------GMRELLALVPQ-------RATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQ  459 (747)
Q Consensus       403 ~~~~~~~~~----------~~~------~~~~~~~~~~~-------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  459 (747)
                      +..+...+.          +-+      -+..++.+...       .+...-.+++..+..+..+.. .+.++.+...+.
T Consensus       169 l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~  247 (487)
T 5ZHX_D          169 LKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVD-NGIVEKLMDLLD  247 (487)
T ss_dssp             HHHHHHHHHHHTTSHHHHHHHSSSSSSSHHHHHHTTTTSSCHHHHHHHHHHHHHHCCSHHHHHHHHT-TTHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhccHHHHHHhhCCCchHHHHHHHHccCCCHHHHHHHHHHHHHHHcCchHHHHHHh-cCHHHHHHHHHH
Confidence            000000000          000      00111111100       000000011111111111000 011222211111


Q NP_000290.2     460 NCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKG  539 (747)
Q Consensus       460 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~  539 (747)
                      ....  .-+..-...+..+|.|+.                                   ..               . ..
T Consensus       248 ~~~~--~~~~~~~~~a~~~l~~l~-----------------------------------~~---------------~-~~  274 (487)
T 5ZHX_D          248 RHVE--DGNVTVQHAALSALRNLA-----------------------------------IP---------------V-IN  274 (487)
T ss_dssp             HTSS--SSCHHHHHHHHHHHHHHT-----------------------------------CS---------------H-HH
T ss_pred             hccc--CCCHHHHHHHHHHHHHhc-----------------------------------CC---------------h-hh
Confidence            0000  000000111111111111                                   00               0 01


Q NP_000290.2     540 SGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS-DVVRSGASL  618 (747)
Q Consensus       540 ~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~-eVr~~AL~a  618 (747)
                      ...+.+.++++.++.++. +.++.++..++++|.+++...+.   . ........++++.++.++.+.+. .++..++++
T Consensus       275 ~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~---~-~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~  349 (487)
T 5ZHX_D          275 KAKMLSAGVTEAVLKFLK-SEMPPVQFKLLGTLRMLIDAQAE---A-AEQLGKNVKLVERLVEWCEAKDHAGVMGESNRL  349 (487)
T ss_dssp             HHHHHHHTHHHHHHTTSS-CCCHHHHHHHHHHHHHHTSSCHH---H-HHHHHHCHHHHHHHHHHHTCCSCCHHHHHHHHH
T ss_pred             HHHHHHcChHHHHHHHHh-CCCHHHHHHHHHHHHHHHhhcHH---H-HHHhccccCHHHHHHHHHHhcCchhhHHHHHHH
Confidence            122345678888888888 46788888999999999875332   1 11221224678888888887665 888999999


Q NP_000290.2     619 LSNMSRHPL---L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP-QLAKQYFSSSMLNNIINLCR  693 (747)
Q Consensus       619 LsnLa~~~e---~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~-e~~~~Lve~giL~~Ll~LL~  693 (747)
                      |.+++....   . ..+...++++.+..++..      .++.++..++.+|.+++...+ .....+.+.++++.++.++.
T Consensus       350 l~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  423 (487)
T 5ZHX_D          350 LSALIRHSKSKDVIKTIVQSGGIKHLVTMATS------EHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRLLA  423 (487)
T ss_dssp             HHHHHHHHCCHHHHHHHHHHTCHHHHHHHTTC------SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHTS
T ss_pred             HHHHHHHhcchhHHHHHHHcchHHHHHHHhcC------CCHHHHHHHHHHHHHHHHcCCCchHHHHhhhhHHHHHHHHHh
Confidence            999986522   2 233445677888888776      367889999999999987542 23333444457888888887


Q NP_000290.2     694 SS-ASPKAAEAARLLLSDMWSSKELQGVLRQQGFD  727 (747)
Q Consensus       694 s~-~d~eVr~aAL~aLsnL~~~~~~~~~~~~~~~~  727 (747)
                      .. .++.++..++.+|.+++...+....+...|+-
T Consensus       424 ~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~  458 (487)
T 5ZHX_D          424 DERSAPEIKYNSMVLICALMGSECLHKEVQDLAFL  458 (487)
T ss_dssp             SSCCSTTCTHHHHHHHHTSCSSSCCSTTTTTHHHH
T ss_pred             cccCcHHHHHHHHHHHHHHhCcHHHHHHHHHhchH
Confidence            32 15788999999999999887766666555543


No 22
>1EE4_A KARYOPHERIN ALPHA; ARM repeat, TRANSPORT PROTEIN; 2.1A {Saccharomyces cerevisiae} SCOP: a.118.1.1
Probab=98.36  E-value=8.2e-11  Score=117.69  Aligned_cols=364  Identities=16%  Similarity=0.224  Sum_probs=221.8  Template_Neff=13.200

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLRSPN-QNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~s~d-~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      ++.+...+.+.++.++..++..+..++..... ....+...++++.+...+...+ +.++..++.++..++.........
T Consensus         3 ~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~~~~~   82 (423)
T 1EE4_A            3 LPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKV   82 (423)
T ss_dssp             HHHHHHHHTCSCHHHHHHHHHHHHHHHCCSSSCSHHHHHHTTCHHHHHHTTSTTSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             hHHHHHHhccccHHHHHHHHHHHHHHHhCCCCCchHHHHhcChHHHHHHHhhcCCcHHHHHHHHHHHHHHhCCCHHHHHH
Confidence            44566666777788888888888888754321 2222333456777777776543 667888899998887644333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.|..++...                ++++
T Consensus        83 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~  145 (423)
T 1EE4_A           83 VVDADAVPLFIQLLY-TGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSN----------------KPSL  145 (423)
T ss_dssp             HHHTTHHHHHHHHHH-HSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHHTTSC----------------CHHH
T ss_pred             HHhCChHHHHHHHHh-CCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHHhcC----------------CHHH
Confidence            333456777777776 5677888899999998886532 2223333 6667776666421                2344


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      -..+..++..-...                     ...........+++..|...+..      .+......+...|.++
T Consensus       146 ~~~a~~~l~~l~~~---------------------~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l  198 (423)
T 1EE4_A          146 IRTATWTLSNLCRG---------------------KKPQPDWSVVSQALPTLAKLIYS------MDTETLVDACWAISYL  198 (423)
T ss_dssp             HHHHHHHHHHHHCC---------------------STTCCCHHHHGGGHHHHHHHTTC------SCHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHcC---------------------CCCCCChHHHhhHHHHHHHHHHc------CCHHHHHHHHHHHHHH
Confidence            44444443321100                     00000111122334433333221      1111112222222222


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ...                                                  +......+.+.++++.+..++. +.++
T Consensus       199 ~~~--------------------------------------------------~~~~~~~~~~~~~~~~l~~~l~-~~~~  227 (423)
T 1EE4_A          199 SDG--------------------------------------------------PQEAIQAVIDVRIPKRLVELLS-HEST  227 (423)
T ss_dssp             TSS--------------------------------------------------CHHHHHHHHHTTHHHHHHHHTT-CSCH
T ss_pred             hcC--------------------------------------------------CHHHHHHHHhcCHHHHHHHHhc-CCCc
Confidence            110                                                  0001112234567778888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFPEV  640 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~~L  640 (747)
                      .++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.. +.. ..+...++++.+
T Consensus       228 ~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l  302 (423)
T 1EE4_A          228 LVQTPALRAVGNIVTGNDL-----QTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPL  302 (423)
T ss_dssp             HHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHH
T ss_pred             chhHHHHHHHHHHHhCChH-----HHHHHHHcChHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHH
Confidence            8888999999998865332     122333457888888888888888999999999999875 222 334455677888


Q NP_000290.2     641 TRLLTSHTGNTSNSEDILSSACYTVRNLMASQ---PQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKEL  717 (747)
Q Consensus       641 l~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s---~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~~  717 (747)
                      ..++.+      .++.++..++.+|.+++...   +.....+.+.++++.+..++.+. ++.++..++.+|.+++...+.
T Consensus       303 ~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~a~~~l~~l~~~~~~  375 (423)
T 1EE4_A          303 VKLLEV------AEDKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIA-DNRIIEVTLDALENILKMGEA  375 (423)
T ss_dssp             HHHHHH------SCHHHHHHHHHHHHHHHGGGGTCHHHHHHHHHTTCHHHHHHGGGSS-CHHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHhc------CCHHHHHHHHHHHHHHHcCCCCcHHHHHHHHHCCCHHHHHHHHhcC-CHHHHHHHHHHHHHHHHHHHH
Confidence            888766      36788999999999998753   23334444456788888888876 788999999999999876554


No 23
>1EE4_B KARYOPHERIN ALPHA; ARM repeat, TRANSPORT PROTEIN; 2.1A {Saccharomyces cerevisiae} SCOP: a.118.1.1
Probab=98.36  E-value=8.2e-11  Score=117.69  Aligned_cols=364  Identities=16%  Similarity=0.224  Sum_probs=221.8  Template_Neff=13.200

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLRSPN-QNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~s~d-~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      ++.+...+.+.++.++..++..+..++..... ....+...++++.+...+...+ +.++..++.++..++.........
T Consensus         3 ~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~~~~~   82 (423)
T 1EE4_B            3 LPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKV   82 (423)
T ss_dssp             HHHHHHHHTSSCHHHHHHHHHHHHHHHCCSSSCCHHHHHHTTCHHHHHHTTSTTSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             hHHHHHHhccccHHHHHHHHHHHHHHHhCCCCCchHHHHhcChHHHHHHHhhcCCcHHHHHHHHHHHHHHhCCCHHHHHH
Confidence            44566666777788888888888888754321 2222333456777777776543 667888899998887644333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.|..++...                ++++
T Consensus        83 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~  145 (423)
T 1EE4_B           83 VVDADAVPLFIQLLY-TGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSN----------------KPSL  145 (423)
T ss_dssp             HHHTTHHHHHHHHHH-HSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHGGGSC----------------CHHH
T ss_pred             HHhCChHHHHHHHHh-CCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHHhcC----------------CHHH
Confidence            333456777777776 5677888899999998886532 2223333 6667776666421                2344


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      -..+..++..-...                     ...........+++..|...+..      .+......+...|.++
T Consensus       146 ~~~a~~~l~~l~~~---------------------~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l  198 (423)
T 1EE4_B          146 IRTATWTLSNLCRG---------------------KKPQPDWSVVSQALPTLAKLIYS------MDTETLVDACWAISYL  198 (423)
T ss_dssp             HHHHHHHHHHHHCC---------------------SSSCCCHHHHGGGHHHHHHHTTC------SCHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHcC---------------------CCCCCChHHHhhHHHHHHHHHHc------CCHHHHHHHHHHHHHH
Confidence            44444443321100                     00000111122334433333221      1111112222222222


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ...                                                  +......+.+.++++.+..++. +.++
T Consensus       199 ~~~--------------------------------------------------~~~~~~~~~~~~~~~~l~~~l~-~~~~  227 (423)
T 1EE4_B          199 SDG--------------------------------------------------PQEAIQAVIDVRIPKRLVELLS-HEST  227 (423)
T ss_dssp             HSS--------------------------------------------------CHHHHHHHHHTTHHHHHHHHTT-CSCH
T ss_pred             hcC--------------------------------------------------CHHHHHHHHhcCHHHHHHHHhc-CCCc
Confidence            110                                                  0001112234567778888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFPEV  640 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~~L  640 (747)
                      .++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.. +.. ..+...++++.+
T Consensus       228 ~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l  302 (423)
T 1EE4_B          228 LVQTPALRAVGNIVTGNDL-----QTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPL  302 (423)
T ss_dssp             HHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHH
T ss_pred             chhHHHHHHHHHHHhCChH-----HHHHHHHcChHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHH
Confidence            8888999999998865332     122333457888888888888888999999999999875 222 334455677888


Q NP_000290.2     641 TRLLTSHTGNTSNSEDILSSACYTVRNLMASQ---PQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKEL  717 (747)
Q Consensus       641 l~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s---~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~~  717 (747)
                      ..++.+      .++.++..++.+|.+++...   +.....+.+.++++.+..++.+. ++.++..++.+|.+++...+.
T Consensus       303 ~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~a~~~l~~l~~~~~~  375 (423)
T 1EE4_B          303 VKLLEV------AEDKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIA-DNRIIEVTLDALENILKMGEA  375 (423)
T ss_dssp             HHHHHH------SCHHHHHHHHHHHHHHHGGGGTCTHHHHHHHHTTCHHHHHHGGGSS-CHHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHhc------CCHHHHHHHHHHHHHHHcCCCCcHHHHHHHHHCCCHHHHHHHHhcC-CHHHHHHHHHHHHHHHHHHHH
Confidence            888766      36788999999999998753   23334444456788888888876 788999999999999876554


No 24
>4EV8_A Catenin beta-1; mouse catenin, CELL ADHESION; HET: URE; 1.9A {Mus musculus}
Probab=98.34  E-value=9.8e-11  Score=121.45  Aligned_cols=382  Identities=19%  Similarity=0.227  Sum_probs=226.5  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..++.........+...++++.+...+.+.+..++..++.++..++.........+
T Consensus       103 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  182 (538)
T 4EV8_A          103 GIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLII  182 (538)
T ss_pred             cHHHHHHHhCCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            45556666666677888889999988876543333333345677788888877778888999999998886444333334


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFF  404 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~  404 (747)
                      ...++++.+...+....+..++..++.++..+.........+.. ++++.+..++...                ++++..
T Consensus       183 ~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~~~  246 (538)
T 4EV8_A          183 LASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDP----------------SQRLVQ  246 (538)
T ss_pred             HHCChHHHHHHHHcCCCCHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHhcCC----------------CHHHHH
Confidence            44457777777776333567788888888888765444333433 6667777666432                233333


Q NP_000290.2     405 NATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSY  484 (747)
Q Consensus       405 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  484 (747)
                      .+..++..-..                     .......+   .+.+..+...+..      .+..-...+...|.++..
T Consensus       247 ~a~~~l~~l~~---------------------~~~~~~~~---~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~  296 (538)
T 4EV8_A          247 NCLWTLRNLSD---------------------AATKQEGM---EGLLGTLVQLLGS------DDINVVTCAAGILSNLTC  296 (538)
T ss_pred             HHHHHHHHHHc---------------------CCCchHHH---cCcHHHHHHHhcC------CCHHHHHHHHHHHHHHHc
Confidence            33333322110                     00000001   2333333333321      111112222222333221


Q NP_000290.2     485 RLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK-SKKDA  563 (747)
Q Consensus       485 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s-s~d~e  563 (747)
                      .-                                                  ......+.+.++++.++..+.. ..++.
T Consensus       297 ~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~~~~~~~~  326 (538)
T 4EV8_A          297 NN--------------------------------------------------YKNKMMVCQVGGIEALVRTVLRAGDRED  326 (538)
T ss_pred             CC--------------------------------------------------HHHHHHHHHCCcHHHHHHHHhcCCCCHH
Confidence            00                                                  0011122455677777776652 14566


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVT  641 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll  641 (747)
                      ++..++.+|.+++.....  .......+...++++.|..++.+. +..++..++.+|.+++..... ..+...++++.+.
T Consensus       327 ~~~~a~~~l~~l~~~~~~--~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~  404 (538)
T 4EV8_A          327 ITEPAICALRHLTSRHQE--AEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLV  404 (538)
T ss_pred             HHHHHHHHHHHHHcCCCC--hHHHHHHHHHCCHHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCHHHHHHHHHCChHHHHH
Confidence            778899999998865331  000012223457788888888765 678889999999999876433 3344556778888


Q NP_000290.2     642 RLLTSHTGNT----------------SNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       642 ~LL~s~s~~~----------------~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .++.......                ...+.++..++.+|.+++.. ......+...++++.++.++.+. ++.++..++
T Consensus       405 ~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~-~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~a~  482 (538)
T 4EV8_A          405 QLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARD-VHNRIVIRGLNTIPLFVQLLYSP-IENIQRVAA  482 (538)
T ss_pred             HHHcCCCcchhhhhccCchHHHHHhcCCCHHHHHHHHHHHHHHhCC-cchhHHHHHcChHHHHHHHhcCC-CHHHHHHHH
Confidence            7776521000                00156677899999999875 33344445556788888888876 788999999


Q NP_000290.2     706 LLLSDMWSSKELQGVLRQQGFD  727 (747)
Q Consensus       706 ~aLsnL~~~~~~~~~~~~~~~~  727 (747)
                      .+|.+++...+....+.+.|+-
T Consensus       483 ~~l~~l~~~~~~~~~~~~~~~~  504 (538)
T 4EV8_A          483 GVLCELAQDKEAAEAIEAEGAT  504 (538)
T ss_pred             HHHHHHHcCHHHHHHHHHCCcH
Confidence            9999999877665555544443


No 25
>4RXH_B Importin subunit alpha, Large T; ARM repeat, NLS, nuclear import; 1.7553A {Neurospora crassa}
Probab=98.34  E-value=1.1e-10  Score=121.65  Aligned_cols=365  Identities=17%  Similarity=0.175  Sum_probs=215.9  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..++.........+...++++.+...+.+.++.++..++.++..++..........
T Consensus        72 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~  151 (495)
T 4RXH_B           72 VVGRFVEFLRSPHTLVQFEAAWALTNIASGSATQTQVVIEAGAVPIFVELLGSPEPDVREQAVWALGNIAGDSPQCRDYV  151 (495)
T ss_dssp             CHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHhCCChHHHHHHHhCChHHHHHHHhcCCCHHHHHHHHHHHHHHHCCCHHHHHHH
Confidence            45566666666777888889999988876543333333345677788888887778889999999998886533333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEE-LIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~-Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ...++++.+...+....++.++..++.++..++........ ... ++++.+..++..+                ++++-
T Consensus       152 ~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~v~  215 (495)
T 4RXH_B          152 LSCGALRPLLTLLGDSRKLSMLRNATWTLSNFCRGKTPQPDWNTIAPALPVLAKLVYSL----------------DDEVL  215 (495)
T ss_dssp             HHTTCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCTTCCCHHHHTTHHHHHHHHTTCS----------------SHHHH
T ss_pred             HhCCcHHHHHHHhccccCHHHHHHHHHHHHHHhCCCCCCCcHHhhcCHHHHHHHHhhCC----------------CHHHH
Confidence            33456777777775333567888889999988875422211 112 5666666666431                23333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-.                     .........---.+++..|...++.      .+..-...+...|.++.
T Consensus       216 ~~a~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  268 (495)
T 4RXH_B          216 IDACWAISYLS---------------------DGSNDKIQAVIEAGIPRRLVELLMH------ASTSVQTPALRSVGNIV  268 (495)
T ss_dssp             HHHHHHHHHHT---------------------SSCHHHHHHHHHTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHh---------------------cCCHHHHHHHHHCChHHHHHHHHhc------CCccHHHHHHHHHHHHh
Confidence            33333332110                     0000000000011344444443321      01111122222222222


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ..-                                                  ......+.+.++++.++.++. +.++.
T Consensus       269 ~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~~  297 (495)
T 4RXH_B          269 TGD--------------------------------------------------DVQTQVIINCGALPCLLSLLS-SNKDG  297 (495)
T ss_dssp             TSC--------------------------------------------------HHHHHHHHHTTHHHHHHHHTT-CSCHH
T ss_pred             cCC--------------------------------------------------HHHHHHHHhCCHHHHHHHHHh-CCCHH
Confidence            100                                                  001112234567778888887 46778


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP----LL-HRVMGNQVFP  638 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~----e~-~~ll~~giI~  638 (747)
                      ++..++.+|.+++.....     ....+...++++.|..++.+.++.++..++.+|.+++...    .. ..+...++++
T Consensus       298 v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~  372 (495)
T 4RXH_B          298 IRKEACWTISNITAGNSA-----QIQSVIDANIIPPLIHLLSHADLKTRKEACWAISNATSGGLQKPDQIRYLVAQGCIK  372 (495)
T ss_dssp             HHHHHHHHHHHHHTSCHH-----HHHHHHHTTCHHHHHHHHHSSCHHHHHHHHHHHHHTTTTTTTCTHHHHHHHHTTCHH
T ss_pred             HHHHHHHHHHHHHcCCHH-----HHHHHHHCCcHHHHHHHHhcCCHHHHHHHHHHHHHHHhcCCCCHHHHHHHHHCCCHH
Confidence            888899999998764332     1223344578888888888778888889999999988752    11 2233446777


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL--------------AKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~--------------~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      .+..++.+      .++.++..++.+|.+++......              ...+.+.++++.|..++.+. ++.++..+
T Consensus       373 ~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~ll~~~-~~~v~~~a  445 (495)
T 4RXH_B          373 PLCDLLAC------PDNKIIQVALDGLENILKVGELDKNAAGDGPDSINRYALFIEECGGMEKIHDCQTNA-NEEIYMKA  445 (495)
T ss_dssp             HHHHGGGC------SCHHHHHHHHHHHHHHHHHHHHHHHTC-----CCCHHHHHHHHTTHHHHHHHGGGCC-SSTTHHHH
T ss_pred             HHHHHhhC------CCHHHHHHHHHHHHHHHHHhhHccccCCCCCchHHHHHHHHHHccchHHHHHhhhcC-CHHHHHHH
Confidence            77777766      36778888999999888753211              22333455677788888766 78899999


Q NP_000290.2     705 RLLLSDMWSSKE  716 (747)
Q Consensus       705 L~aLsnL~~~~~  716 (747)
                      +.+|.+++...+
T Consensus       446 ~~~l~~l~~~~~  457 (495)
T 4RXH_B          446 YNIIEKYFSDED  457 (495)
T ss_dssp             HHHHHHHCC---
T ss_pred             HHHHHHhcCccc
Confidence            999999886544


No 26
>4BQK_A IMPORTIN SUBUNIT ALPHA-1A, T-DNA BORDER; TRANSPORT PROTEIN, HYDROLASE, NUCLEAR LOCALIZATION; HET: PEG; 1.997A {ORYZA SATIVA}
Probab=98.32  E-value=1.2e-10  Score=118.46  Aligned_cols=366  Identities=17%  Similarity=0.164  Sum_probs=217.0  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQD-EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd-~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+.+ +.++..++.++..++.........+...++++.+..++.+.+..++..++.++..++.........
T Consensus        46 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  125 (456)
T 4BQK_A           46 VVPRFVQFLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSDDVREQAVWALGNVAGDSPKCRDL  125 (456)
T ss_dssp             CHHHHHHHTTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHH
T ss_pred             cHHHHHHHhccCcCHHHHHHHHHHHHHHhcCCHhHHHHHHhccHHHHHHHHhcCCCHHHHHHHHHHHHHHHCCCHHHHHH
Confidence            4455566665543 778888899998887554443333444567778888887777888899999999887653333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      +...+.+..++..+....++.++..++.++..++........... ++++.|..++...                ++++-
T Consensus       126 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~~  189 (456)
T 4BQK_A          126 VLANGALLPLLAQLNEHTKLSMLRNATWTLSNFCRGKPQPSFEQTRPALPALARLIHSN----------------DEEVL  189 (456)
T ss_dssp             HHHTTCHHHHHHTCCTTCCHHHHHHHHHHHHHHHCSSSCCCHHHHTTHHHHHHHHTTCC----------------CHHHH
T ss_pred             HHHCCcHHHHHHHHhhCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHhcCC----------------CHHHH
Confidence            333455666666665334567888888888888775433222222 5666666666431                23333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-..      ..+              ..++.. .-.+++..|...+..      .+..-...+...|.++.
T Consensus       190 ~~a~~~l~~l~~------~~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  242 (456)
T 4BQK_A          190 TDACWALSYLSD------GTN--------------DKIQAV-IEAGVCPRLVELLLH------PSPSVLIPALRTVGNIV  242 (456)
T ss_dssp             HHHHHHHHHHTS------SSH--------------HHHHHH-HHTTCHHHHHHHTTC------SCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHhc------CCh--------------HHHHHH-HHCChHHHHHHHHhC------CCHHHHHHHHHHHHHHH
Confidence            333333322110      000              000000 012334444333321      11111222222222222


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ..-                                                  ......+.+.++++.++.++....++.
T Consensus       243 ~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~~~~~~~  272 (456)
T 4BQK_A          243 TGD--------------------------------------------------DAQTQCIIDHQALPCLLSLLTQNLKKS  272 (456)
T ss_dssp             TSC--------------------------------------------------HHHHHHHHTTTHHHHHHHHHHSCCCHH
T ss_pred             cCC--------------------------------------------------HHHHHHHHHCChHHHHHHHHHcCCCHH
Confidence            100                                                  000112244567888888887322677


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH--PLL-HRVMGNQVFPEV  640 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~--~e~-~~ll~~giI~~L  640 (747)
                      ++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++..  ... ..+...++++.+
T Consensus       273 ~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l  347 (456)
T 4BQK_A          273 IKKEACWTISNITAGNKD-----QIQAVINAGIIGPLVNLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIKPL  347 (456)
T ss_dssp             HHHHHHHHHHHHHTSCHH-----HHHHHHHHTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHTTCHHHH
T ss_pred             HHHHHHHHHHHHhcCCHH-----HHHHHHHCCcHHHHHHHhhcCCHHHHHHHHHHHHHHHcCCCHHHHHHHHHCCCHHHH
Confidence            888999999999865332     233334567888899999888888999999999999875  222 233344677888


Q NP_000290.2     641 TRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL-----------AKQYFSSSMLNNIINLCRSSASPKAAEAARLLLS  709 (747)
Q Consensus       641 l~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~-----------~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLs  709 (747)
                      ..++.+      .++.++..++.+|.+++...+..           ...+.+.+.++.+..++.+. ++.++..++.+|.
T Consensus       348 ~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~ll~~~-~~~v~~~a~~~l~  420 (456)
T 4BQK_A          348 CDLLIC------PDIRIVTVCLEGLENILKVGETDKTLAAGDVNVFSQMIDEAEGLEKIENLQSHD-NNEIYEKAVKILE  420 (456)
T ss_dssp             HHGGGS------SCHHHHHHHHHHHHHHHHHHHHHHHHTTCSCCHHHHHHHHTTHHHHHHHHTTCS-CHHHHHHHHHHHH
T ss_pred             HHHhhC------CChHHHHHHHHHHHHHHHHhhhchhccCCCCCHHHHHHHHcchHHHHHHHHcCC-CHHHHHHHHHHHH
Confidence            888776      36788899999999998753321           11122245677788888766 7889999999999


Q NP_000290.2     710 DMWSSKE  716 (747)
Q Consensus       710 nL~~~~~  716 (747)
                      +++...+
T Consensus       421 ~l~~~~~  427 (456)
T 4BQK_A          421 AYWMDEE  427 (456)
T ss_dssp             HHCC---
T ss_pred             HHhcCcc
Confidence            9887544


No 27
>6BW9_A Importin subunit alpha-3, Protein W; Complex, Hendra virus, Importin, Karyopherin; 1.6A {Homo sapiens}
Probab=98.31  E-value=1.3e-10  Score=118.46  Aligned_cols=366  Identities=17%  Similarity=0.199  Sum_probs=218.4  Template_Neff=12.900

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+. ..++.++..++.++..++.........+...++++.+...+.+.+..++..++.++..++.........
T Consensus        53 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  132 (459)
T 6BW9_A           53 ILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDY  132 (459)
T ss_dssp             HHHHHHHHTTCTTCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHHTTCHHHHHH
T ss_pred             hHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHhhCCHHHHHHHHhcCCChHHHHHHHHHHHHHHcCCHHHHHH
Confidence            4555666665 456778888899998887654433333344567778888887777888999999999887654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEEL-I-ADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~L-v-egiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...+++..+...+....+..++..++.++..++......... . .++++.+..++..                .++++
T Consensus       133 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~v  196 (459)
T 6BW9_A          133 VISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHH----------------TDVNI  196 (459)
T ss_dssp             HHHTTCHHHHHHTCSTTSCHHHHHHHHHHHHHHHCCCSSCCCHHHHHHHHHHHHHHTTC----------------CCHHH
T ss_pred             HHHCCcHHHHHhccCCCCCHHHHHHHHHHHHHHhcCCCCCCCHHHHHHHHHHHHHHHhc----------------CCHHH
Confidence            3334566777777653345567888888888887643321111 1 1566666666543                13344


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..++..-...      .+              ...... -..+++..|...++.      .+..-...++..|.++
T Consensus       197 ~~~a~~~l~~l~~~------~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l  249 (459)
T 6BW9_A          197 LVDTVWALSYLTDA------GN--------------EQIQMV-IDSGIVPHLVPLLSH------QEVKVQTAALRAVGNI  249 (459)
T ss_dssp             HHHHHHHHHHHHTS------CH--------------HHHHHH-HHTTCHHHHGGGGGC------SSHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhhc------Ch--------------HHHHHH-HhCChHHHHHHHcCC------CCHHHHHHHHHHHHHH
Confidence            44444333221100      00              000000 012334444333321      1111122223333333


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ....+                                                  .....+.+.++++.++.++. +.++
T Consensus       250 ~~~~~--------------------------------------------------~~~~~~~~~~~~~~l~~~l~-~~~~  278 (459)
T 6BW9_A          250 VTGTD--------------------------------------------------EQTQVVLNCDALSHFPALLT-HPKE  278 (459)
T ss_dssp             TTSCH--------------------------------------------------HHHHHHHTTTGGGGCHHHHT-CSCH
T ss_pred             HcCCH--------------------------------------------------HHHHHHhcccchhcHHHHhh-CCCH
Confidence            21100                                                  00111234467788888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGNQVFPE  639 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~giI~~  639 (747)
                      .++..++.+|.+++.....     ....+...++++.|..++.+.++.++..++.+|.+++.. . .. ......++++.
T Consensus       279 ~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~  353 (459)
T 6BW9_A          279 KINKEAVWFLSNITAGNQQ-----QVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPP  353 (459)
T ss_dssp             HHHHHHHHHHHHHHTSCHH-----HHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHTTCHHH
T ss_pred             HHHHHHHHHHHHHcCCCHH-----HHHHHHHCCHHHHHHHHHHhCCHHHHHHHHHHHHHHHHhCCHHHHHHHHHCCcHHH
Confidence            8888999999999865332     223334557888888888888888999999999999864 2 21 23334467788


Q NP_000290.2     640 VTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA----KQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       640 Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~----~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      +..++.+      .++.++..++.+|.+++...+...    ..+...++++.+..++.+. ++.++..++.+|.+++...
T Consensus       354 l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~~~  426 (459)
T 6BW9_A          354 FCNLLTV------KDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHE-NEDIYKLAYEIIDQFFSSD  426 (459)
T ss_dssp             HHGGGGC------SCHHHHHHHHHHHHHHHHHCTTTHHHHHHHHHHTTHHHHHHHHTTCS-CHHHHHHHHHHHHHHSCC-
T ss_pred             HHHhcCC------CCHHHHHHHHHHHHHHHHHhHhhHHHHHHHHHHcCHHHHHHHHhcCC-CHHHHHHHHHHHHHHcCCC
Confidence            8888776      367888999999999987533221    1233346778888888766 7889999999999998766


Q NP_000290.2     716 EL  717 (747)
Q Consensus       716 ~~  717 (747)
                      +.
T Consensus       427 ~~  428 (459)
T 6BW9_A          427 DI  428 (459)
T ss_dssp             --
T ss_pred             CC
Confidence            54


No 28
>1WA5_B GTP-BINDING NUCLEAR PROTEIN RAN, IMPORTIN; NUCLEAR TRANSPORT-COMPLEX, NUCLEAR TRANSPORT, EXPORTIN; HET: GTP; 2.0A {CANIS FAMILIARIS} SCOP: a.118.1.1
Probab=98.27  E-value=1.9e-10  Score=121.37  Aligned_cols=134  Identities=13%  Similarity=0.098  Sum_probs=85.4  Template_Neff=12.300

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++.+++...+.....+...++++.+..++.+.+..++..++.++..++.........
T Consensus       173 ~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  252 (530)
T 1WA5_B          173 DAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDW  252 (530)
T ss_dssp             TCHHHHHHHHHHCCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHGGGSCCHHHHHHHHHHHHHHHCCSSSCCCH
T ss_pred             ChHHHHHHHHhCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCcHHHHHHHhhCCCHHHHHHHHHHHHHHHCCCCCCCCH
Confidence            34556666676777888899999999988654433334444567778888887777888888999998887644222222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRV  379 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL  379 (747)
                      ....++++.+..++. ..++.++..++.++..++.... ....+.. ++++.|+.++
T Consensus       253 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l  308 (530)
T 1WA5_B          253 SVVSQALPTLAKLIY-SMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELL  308 (530)
T ss_dssp             HHHGGGHHHHHHHTT-CCCHHHHHHHHHHHHHHHSSCHHHHHHHHHTTCHHHHHHGG
T ss_pred             HHHhhHHHHHHHHHh-cCCHHHHHHHHHHHHHHcCCCHHHHHHHHhCCHHHHHHHHh
Confidence            223456666777765 4566777778888887776422 2222222 4455555544


No 29
>5XGC_A Rap1 GTPase-GDP dissociation stimulator 1; armadillo GEF, ONCOPROTEIN; 2.1A {Homo sapiens}
Probab=98.27  E-value=2e-10  Score=117.66  Aligned_cols=409  Identities=17%  Similarity=0.214  Sum_probs=224.4  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRS--PNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s--~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      +++.+...+.+.++.++..++.++..++...+.....+...++++.+...+..  .++.++..++.++..++.... ...
T Consensus        35 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~-~~~  113 (503)
T 5XGC_A           35 LISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELES-SKE  113 (503)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHSCCCSHHHHHHHHHTTHHHHHHHHHHHTTTCHHHHHHHHHHHHHHTTSHH-HHH
T ss_pred             cHHHHHHHHcCCCHHHHHHHHHHHHHHHcCCchHHHHHHHCChHHHHHHHHhccCCCHHHHHHHHHHHHHHHccHH-HHH
Confidence            55666777777778889999999999887543333344445677788888776  467888889999988876532 222


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      .+...++++.+...+....++.++..++.++..++........+.. ++++.++.++.......        + ....+.
T Consensus       114 ~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~--------~-~~~~~~  184 (503)
T 5XGC_A          114 QFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSD--------K-EDDITE  184 (503)
T ss_dssp             HHTTTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTSHHHHHHHHHTTHHHHHHHHHHHHTTCC--------C-HHHHHH
T ss_pred             HHhcCCHHHHHHHHHHhcCChhHHHHHHHHHHHHHcCHHHHHHHHHCCHHHHHHHHHHhcCCCC--------C-HHHHHH
Confidence            2334466777777776222677888899999998876444444444 67777777776432100        0 000000


Q NP_000290.2     403 FFNATGCLRKRL----------------GMRELLALVPQR-------ATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQ  459 (747)
Q Consensus       403 ~~~~~~~~~~~~----------------~~~~~~~~~~~~-------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  459 (747)
                      +..+...+..-.                -+..++.+....       +...-.+++..+..+..+.. .|.++.|+..+.
T Consensus       185 l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~-~~~~~~l~~~l~  263 (503)
T 5XGC_A          185 LKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVD-NGIVEKLMDLLD  263 (503)
T ss_dssp             HHHHHHHHHHHTTSHHHHHHHHGGGTCHHHHHHHHHTTSSCHHHHHHHHHHHHHHCSSHHHHHHHHH-TTHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhCCchHHHHHhcCcccHHHHHHHHccCCCHHHHHHHHHHHHHHHCChhHHHHHHH-CCHHHHHHHHHH
Confidence            000000000000                000111110000       00000011111111110000 011222221111


Q NP_000290.2     460 NCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKG  539 (747)
Q Consensus       460 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~  539 (747)
                      ....  .-+..-...++.+|.++.                                   ..               . ..
T Consensus       264 ~~~~--~~~~~~~~~a~~~l~~l~-----------------------------------~~---------------~-~~  290 (503)
T 5XGC_A          264 RHVE--DGNVTVQHAALSALRNLA-----------------------------------IP---------------V-IN  290 (503)
T ss_dssp             TTTT--TCCHHHHHHHHHHHHHHT-----------------------------------CS---------------H-HH
T ss_pred             hccc--cCCHHHHHHHHHHHHHhc-----------------------------------CC---------------H-HH
Confidence            1000  000000011111111111                                   00               0 01


Q NP_000290.2     540 SGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS-DVVRSGASL  618 (747)
Q Consensus       540 ~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~-eVr~~AL~a  618 (747)
                      ...+.+.++++.|..++. +.++.++..++.+|.+++...+.   . ........++++.+..++.+.+. .++..++++
T Consensus       291 ~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~---~-~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~  365 (503)
T 5XGC_A          291 KAKMLSAGVTEAVLKFLK-SEMPPVQFKLLGTLRMLIDAQAE---A-AEQLGKNVKLVERLVEWCEAKDHAGVMGESNRL  365 (503)
T ss_dssp             HHHHHHHTHHHHHHTTTT-CCCHHHHHHHHHHHHHHTTTCHH---H-HHHHHTCHHHHHHHHHHHTCTTCHHHHHHHHHH
T ss_pred             HHHHHHcCHHHHHHHHHc-CCCHHHHHHHHHHHHHHHccCHH---H-HHHHccccchHHHHHHHHccCCccchHHHHHHH
Confidence            122345678888888888 46778888999999999875332   0 11221235678888888877665 888999999


Q NP_000290.2     619 LSNMSRHPL---L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP-QLAKQYFSSSMLNNIINLCR  693 (747)
Q Consensus       619 LsnLa~~~e---~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~-e~~~~Lve~giL~~Ll~LL~  693 (747)
                      |.+++....   . ..+...++++.+..++.+      .++.++..++.+|.+++...+ .....+...++++.+...+.
T Consensus       366 l~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  439 (503)
T 5XGC_A          366 LSALIRHSKSKDVIKTIVQSGGIKHLVTMATS------EHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRLLA  439 (503)
T ss_dssp             HHHHHHHHCCHHHHHHHHHHTHHHHHHHHTTC------SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTHHHHHHHC--
T ss_pred             HHHHHHHccChhHHHHHHhcChHHHHHHHhcC------CCHHHHHHHHHHHHHHHhCCCCcHHHHHHhccHHHHHHHHHh
Confidence            999976522   2 233455677888888876      367889999999999987542 22333444457888888887


Q NP_000290.2     694 SS-ASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN  729 (747)
Q Consensus       694 s~-~d~eVr~aAL~aLsnL~~~~~~~~~~~~~~~~~~  729 (747)
                      .. .++.++..++.+|.+++...+....+...|+..-
T Consensus       440 ~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~  476 (503)
T 5XGC_A          440 DERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDV  476 (503)
T ss_dssp             -----CGGGGHHHHHHHHHTTCSSCCCSGGGTHHHHH
T ss_pred             CCCCcHHHHHHHHHHHHHHhCCHHHHHHHHHhcHHHH
Confidence            32 1578899999999999988776666655555443


No 30
>4BPL_A IMPORTIN SUBUNIT ALPHA-1A, NUCLEOPLASMIN NLS; TRANSPORT PROTEIN, NUCLEAR IMPORT, NUCLEAR; 2.3A {ORYZA SATIVA}
Probab=98.24  E-value=2.4e-10  Score=115.88  Aligned_cols=367  Identities=17%  Similarity=0.164  Sum_probs=216.2  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQD-EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd-~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+...+ +.++..++.++..++.........+...++++.+..++.+.++.++..++.++..++.........
T Consensus        44 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  123 (454)
T 4BPL_A           44 VVPRFVQFLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSDDVREQAVWALGNVAGDSPKCRDL  123 (454)
T ss_dssp             CHHHHHHHHSCTTCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHHHSCHHHHHH
T ss_pred             cHHHHHHHhccCcCHHHHHHHHHHHHHHhcCChhhhHHHhhccHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            4455566665543 778888889998887544433333444567778888887777888999999999887653333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      +...+.+..++..+....++.++..++.++..++........... ++++.|..++..                -++++.
T Consensus       124 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~~~  187 (454)
T 4BPL_A          124 VLANGALLPLLAQLNEHTKLSMLRNATWTLSNFCRGKPQPSFEQTRPALPALARLIHS----------------NDEEVL  187 (454)
T ss_dssp             HHHTTCHHHHHHTCSTTCCHHHHHHHHHHHHHHHCSSSCCCHHHHTTHHHHHHHHTTC----------------CCHHHH
T ss_pred             HHHCCcHHHHHHHHccCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHhC----------------CCHHHH
Confidence            333455666666665334567888888888888765433222222 566666666542                123444


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-...      .+              ..++.. -..+++..|...++.      .+..-...+...|.++.
T Consensus       188 ~~a~~~l~~l~~~------~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  240 (454)
T 4BPL_A          188 TDACWALSYLSDG------TN--------------DKIQAV-IEAGVCPRLVELLLH------PSPSVLIPALRTVGNIV  240 (454)
T ss_dssp             HHHHHHHHHHTSS------CH--------------HHHHHH-HHTTCHHHHHHHTTC------SCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHhcC------Ch--------------HHHHHH-HHCCcHHHHHHHhhC------CChHHHHHHHHHHHHHh
Confidence            4444333221100      00              000000 012334444333321      01111122222222221


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ..                                                  +......+.+.++++.++.++....++.
T Consensus       241 ~~--------------------------------------------------~~~~~~~~~~~~~~~~l~~~l~~~~~~~  270 (454)
T 4BPL_A          241 TG--------------------------------------------------DDAQTQCIIDHQALPCLLSLLTQNLKKS  270 (454)
T ss_dssp             TS--------------------------------------------------CHHHHHHHHTTTHHHHHHHHHHSSCCHH
T ss_pred             cC--------------------------------------------------CHHHHHHHHHCChHHHHHHHHHhcCCHH
Confidence            10                                                  0001112234567888888887322677


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH--PLL-HRVMGNQVFPEV  640 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~--~e~-~~ll~~giI~~L  640 (747)
                      ++..++.+|.+++.....     ....+...++++.|..++.+.++.++..++.+|.+++..  ... ..+...++++.+
T Consensus       271 ~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l  345 (454)
T 4BPL_A          271 IKKEACWTISNITAGNKD-----QIQAVINAGIIGPLVNLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIKPL  345 (454)
T ss_dssp             HHHHHHHHHHHHHTSCHH-----HHHHHHHHTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHTTCHHHH
T ss_pred             HHHHHHHHHHHHhcCCHH-----HHHHHHhCCcHHHHHHHhhcCCHHHHHHHHHHHHHHHcCCCHHHHHHHHHCCCHHHH
Confidence            888999999999865332     233334567888899999888888999999999999875  222 233444677888


Q NP_000290.2     641 TRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA-----------KQYFSSSMLNNIINLCRSSASPKAAEAARLLLS  709 (747)
Q Consensus       641 l~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~-----------~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLs  709 (747)
                      ..++.+      .++.++..++.+|.+++.......           ..+.+.+.++.+..++.+. ++.++..++.+|.
T Consensus       346 ~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~  418 (454)
T 4BPL_A          346 CDLLIC------PDIRIVTVCLEGLENILKVGETDKTLAAGDVNVFSQMIDEAEGLEKIENLQSHD-NNEIYEKAVKILE  418 (454)
T ss_dssp             HHTTTC------SCHHHHHHHHHHHHHHHHHHHHHHHHHTCSSCHHHHHHHHTTHHHHHHHGGGCS-CHHHHHHHHHHHH
T ss_pred             HHHhcC------CChHHHHHHHHHHHHHHHHhhhchhcccCCCCHHHHHHHHcccHHHHHHHHcCC-CHHHHHHHHHHHH
Confidence            888776      367888899999999987532211           1112245677788888766 7889999999999


Q NP_000290.2     710 DMWSSKEL  717 (747)
Q Consensus       710 nL~~~~~~  717 (747)
                      .+....+.
T Consensus       419 ~l~~~~~~  426 (454)
T 4BPL_A          419 AYWMDEED  426 (454)
T ss_dssp             HHCC----
T ss_pred             HHhcCccc
Confidence            99876544


No 31
>4B8J_A IMPORTIN SUBUNIT ALPHA-1A; TRANSPORT PROTEIN, NUCLEAR LOCALIZATION SIGNAL; 2.001A {ORYZA SATIVA JAPONICA GROUP}
Probab=98.24  E-value=2.6e-10  Score=119.98  Aligned_cols=367  Identities=17%  Similarity=0.160  Sum_probs=217.7  Template_Neff=12.400

Q NP_000290.2     246 TIPKAVQYLSSQD-EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd-~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+.+ +.++..++.+|..++.........+...++++.+..++.+.+..++..++.+|..++.........
T Consensus       118 ~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  197 (528)
T 4B8J_A          118 VVPRFVQFLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSDDVREQAVWALGNVAGDSPKCRDL  197 (528)
T ss_dssp             CHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHHTCHHHHHH
T ss_pred             cHHHHHHHhcCCCCHHHHHHHHHHHHHHHcCChHHHHHHHhCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            4555666665544 778888999998887544433333444557778888887777888899999999887654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      +...+++..++..+....++.++..++.++..++........... ++++.|..++..                .++++.
T Consensus       198 ~~~~~~l~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~v~  261 (528)
T 4B8J_A          198 VLANGALLPLLAQLNEHTKLSMLRNATWTLSNFCRGKPQPSFEQTRPALPALARLIHS----------------NDEEVL  261 (528)
T ss_dssp             HHHTTCHHHHHHTCCTTCCHHHHHHHHHHHHHHHCSSSCCCHHHHTTHHHHHHHHTTC----------------CCHHHH
T ss_pred             HHHCCcHHHHHHHHccCCCHHHHHHHHHHHHHHhCCCCCCCHHHHhhHHHHHHHHhcC----------------CCHHHH
Confidence            333455666666664334567888888999888875433222222 566666666643                133444


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..+|..-..      ..+              ...+.+ ...++++.|+..++.      .+..-...+...|.++.
T Consensus       262 ~~a~~~l~~l~~------~~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  314 (528)
T 4B8J_A          262 TDACWALSYLSD------GTN--------------DKIQAV-IEAGVCPRLVELLLH------PSPSVLIPALRTVGNIV  314 (528)
T ss_dssp             HHHHHHHHHHTS------SCH--------------HHHHHH-HHTTCHHHHHHHTTC------SCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHhc------CCh--------------HHHHHH-HHCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHH
Confidence            444443322110      000              000000 012344444433321      01111122222222222


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ..-                                                  ......+.+.++++.|+.++....++.
T Consensus       315 ~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~~~~~~~  344 (528)
T 4B8J_A          315 TGD--------------------------------------------------DAQTQCIIDHQALPCLLSLLTQNLKKS  344 (528)
T ss_dssp             TSC--------------------------------------------------HHHHHHHHTTTHHHHHHHHHHSCCCHH
T ss_pred             cCC--------------------------------------------------HHHHHHHHHCChHHHHHHHHhcCCCHH
Confidence            100                                                  001112245567888888887322677


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGNQVFPEV  640 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~giI~~L  640 (747)
                      ++..++.+|.+++.....     ....+...++++.|..++.+.++.++..++.+|.+++.. . .. ..+...++++.|
T Consensus       345 v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l  419 (528)
T 4B8J_A          345 IKKEACWTISNITAGNKD-----QIQAVINAGIIGPLVNLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIKPL  419 (528)
T ss_dssp             HHHHHHHHHHHHHTSCHH-----HHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHSCHHHHHHHHHTTCHHHH
T ss_pred             HHHHHHHHHHHHHcCCHH-----HHHHHHHCCchHHHHHHHhcCCHHHHHHHHHHHHHHHcCCCHHHHHHHHHCCCHHHH
Confidence            888999999999865332     233334567888999999888888999999999999875 2 22 233344677888


Q NP_000290.2     641 TRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL-----------AKQYFSSSMLNNIINLCRSSASPKAAEAARLLLS  709 (747)
Q Consensus       641 l~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~-----------~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLs  709 (747)
                      ..++.+      .++.++..++.+|.+++......           ...+.+.++++.|..++.+. ++.++..|+.+|.
T Consensus       420 ~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~ll~~~-~~~v~~~a~~~l~  492 (528)
T 4B8J_A          420 CDLLIC------PDIRIVTVCLEGLENILKVGETDKTLAAGDVNVFSQMIDEAEGLEKIENLQSHD-NNEIYEKAVKILE  492 (528)
T ss_dssp             HHGGGC------SCHHHHHHHHHHHHHHHHHHHHHHHHHTCSCCHHHHHHHHTTHHHHHHHGGGCS-SHHHHHHHHHHHH
T ss_pred             HHHccC------CCHHHHHHHHHHHHHHHHHhHHcHhhcCCCCcHHHHHHHHcCHHHHHHHHhcCC-CHHHHHHHHHHHH
Confidence            888776      36788899999999998753221           11122345677788888766 7889999999999


Q NP_000290.2     710 DMWSSKEL  717 (747)
Q Consensus       710 nL~~~~~~  717 (747)
                      +++...+.
T Consensus       493 ~l~~~~~~  500 (528)
T 4B8J_A          493 AYWMDEED  500 (528)
T ss_dssp             HHCC----
T ss_pred             Hhcccccc
Confidence            98875544


No 32
>5T94_B Guanine nucleotide exchange factor SRM1; Nuclear Import, Importin alpha, RCC1; 2.631A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=98.23  E-value=2.9e-10  Score=120.53  Aligned_cols=364  Identities=15%  Similarity=0.171  Sum_probs=219.0  Template_Neff=12.200

Q NP_000290.2     246 TIPKAVQYLSSQD-EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd-~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.++..+.+.+ +.++..++.+|..++.........+...++++.+...+.+.++.++..++.++..++.........
T Consensus       131 ~~~~L~~~l~~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  210 (542)
T 5T94_B          131 VVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDY  210 (542)
T ss_dssp             CHHHHHHTTSSSSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCHHHHHH
T ss_pred             hHHHHHHHhhcCCCHHHHHHHHHHHHHHHcCChHHHHHHhcCChHHHHHHHHhCCCHHHHHHHHHHHHHHHCCCHHHHHH
Confidence            4555666665443 677888899998887654333333334567777888887777888999999999988654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...++++.+..++. ..++.++..++.+|..++.... ....... ++++.|+.++..                .++++
T Consensus       211 ~~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~~  273 (542)
T 5T94_B          211 VLQCNAMEPILGLFN-SNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYS----------------MDTET  273 (542)
T ss_dssp             HHHTTCHHHHHHGGG-CCCHHHHHHHHHHHHHHSCCSTTCCCHHHHGGGHHHHHHHTTC----------------CCHHH
T ss_pred             HHHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCCCCCCHHHHhcHHHHHHHHHhc----------------CCHHH
Confidence            344467777777776 5567788889999998887542 2222222 566777766642                12334


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..+|..-...      -+              ...+.+. -.+++..|...++.      .+..-...+...|.++
T Consensus       274 ~~~a~~~L~~l~~~------~~--------------~~~~~~~-~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~l  326 (542)
T 5T94_B          274 LVDACWAISYLSDG------PQ--------------EAIQAVI-DVRIPKRLVELLSH------ESTLVQTPALRAVGNI  326 (542)
T ss_dssp             HHHHHHHHHHHSSS------SH--------------HHHHHHH-HTTCHHHHHHTTSC------SSHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHcCC------CH--------------HHHHHHH-hCCHHHHHHHHhcC------CCHHHHHHHHHHHHHH
Confidence            33333333221100      00              0000000 01233333322221      1111112222222222


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ...-                                                  ......+.+.++++.|+.++. +.++
T Consensus       327 ~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~  355 (542)
T 5T94_B          327 VTGN--------------------------------------------------DLQTQVVINAGVLPALRLLLS-SPKE  355 (542)
T ss_dssp             TTSC--------------------------------------------------HHHHHHHHHTTHHHHHHHHTT-CSSH
T ss_pred             HcCC--------------------------------------------------HHHHHHHHHCChHHHHHHHhh-CCCH
Confidence            2100                                                  001111234567888888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL----L-HRVMGNQVF  637 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e----~-~~ll~~giI  637 (747)
                      .++..++++|.+++...+.     ....+...++++.|..++.+.++.++..++++|.+++....    . ..+...+++
T Consensus       356 ~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~  430 (542)
T 5T94_B          356 NIKKEACWTISNITAGNTE-----QIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCI  430 (542)
T ss_dssp             HHHHHHHHHHHHHTTSCHH-----HHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHGGGTTCTHHHHHHHHTTCH
T ss_pred             HHHHHHHHHHHHHhCCCHH-----HHHHHHHCCchHHHHHHHHcCCHHHHHHHHHHHHHHHcCCCCCHHHHHHHHHCCCH
Confidence            8888999999999875332     23333456788888888888888899999999999987621    1 223345678


Q NP_000290.2     638 PEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-----------LAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       638 ~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-----------~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      +.|..++.+      .++.++..++.+|.+++...+.           ....+.+.++++.|..++.+. ++.++..|+.
T Consensus       431 ~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~ll~~~-~~~v~~~a~~  503 (542)
T 5T94_B          431 KPLCDLLEI------ADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNE-NDKIYEKAYK  503 (542)
T ss_dssp             HHHHHHHHH------CCHHHHHHHHHHHHHHHHHHHHHTTTTTCSSCTTTHHHHHTTCHHHHHTTSSSC-CHHHHHHHHH
T ss_pred             HHHHHHhcC------CCHHHHHHHHHHHHHHHHHHHHHHHHcCCCccHHHHHHHHcCHHHHHHHHHhCC-CHHHHHHHHH
Confidence            888888876      3677888999999999875332           123344456788888888766 7889999999


Q NP_000290.2     707 LLSDMWSSKE  716 (747)
Q Consensus       707 aLsnL~~~~~  716 (747)
                      +|.+++...+
T Consensus       504 ~l~~l~~~~~  513 (542)
T 5T94_B          504 IIETYFGEEE  513 (542)
T ss_dssp             HHHHHC----
T ss_pred             HHHHHhCcCc
Confidence            9999987543


No 33
>4TNM_A Importin-alpha3 / MOS6; armadillo repeat; 2.9A {Arabidopsis thaliana}
Probab=98.21  E-value=3.2e-10  Score=119.57  Aligned_cols=369  Identities=17%  Similarity=0.184  Sum_probs=220.4  Template_Neff=12.300

Q NP_000290.2     246 TIPKAVQYLSSQD-EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd-~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+.+ +.++..++.++..++.........+...++++.+..++.+.++.++..++.++..++.........
T Consensus       119 ~~~~l~~~l~~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  198 (531)
T 4TNM_A          119 VVPRVVKFLSRDDFPKLQFEAAWALTNIASGTSENTNVIIESGAVPIFIQLLSSASEDVREQAVWALGNVAGDSPKCRDL  198 (531)
T ss_pred             CHHHHHHHhcCCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCCHHHHHHHccCCCHHHHHHHHHHHHHHhcCCHHHHHH
Confidence            4555666665544 778888889998887644333333444567778888887777888999999999887653333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      +...+++..+...+....+..++..++.++..++........... ++++.|..++...                ++++.
T Consensus       199 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~v~  262 (531)
T 4TNM_A          199 VLSYGAMTPLLSQFNENTKLSMLRNATWTLSNFCRGKPPPAFEQTQPALPVLERLVQSM----------------DEEVL  262 (531)
T ss_pred             HHHCCCHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCCCCcchhhhcchHHHHHHHhcCC----------------CHHHH
Confidence            333456666666664334567888888898888765433222222 5666666665431                33444


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..+|..-..                     .+......-.-.+++..|...+..      .+..-...+...|.++.
T Consensus       263 ~~a~~~l~~l~~---------------------~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~L~~l~  315 (531)
T 4TNM_A          263 TDACWALSYLSD---------------------NSNDKIQAVIEAGVVPRLIQLLGH------SSPSVLIPALRTIGNIV  315 (531)
T ss_pred             HHHHHHHHHHhC---------------------CCHHHHHHHHHCChHHHHHHHHhC------CCHHHHHHHHHHHHHHH
Confidence            444433322110                     000000000012334444333321      11112222233333322


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ...+                                                  .....+.+.++++.|+.++....++.
T Consensus       316 ~~~~--------------------------------------------------~~~~~~~~~~~~~~l~~~l~~~~~~~  345 (531)
T 4TNM_A          316 TGDD--------------------------------------------------LQTQMVLDQQALPCLLNLLKNNYKKS  345 (531)
T ss_pred             CCCH--------------------------------------------------HHHHHHHHCCcHHHHHHHhcCCCCHH
Confidence            1100                                                  00111234467788888887323567


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PL-L-HRVMGNQVFPEV  640 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e-~-~~ll~~giI~~L  640 (747)
                      ++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++++|.+++.. .. . ..+...++++.|
T Consensus       346 v~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l  420 (531)
T 4TNM_A          346 IKKEACWTISNITAGNAD-----QIQAVIDAGIIQSLVWVLQSAEFEVKKEAAWGISNATSGGTHDQIKFMVSQGCIKPL  420 (531)
T ss_pred             HHHHHHHHHHHHHCCCHH-----HHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHHHHHCCcHHHH
Confidence            888999999999875332     233334566888888888887888999999999999875 21 2 233344677888


Q NP_000290.2     641 TRLLTSHTGNTSNSEDILSSACYTVRNLMASQ------------PQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       641 l~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s------------~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      ..++.+      .++.++..++.+|.+++...            ......+.+.++++.|..++.+. ++.++..|+.+|
T Consensus       421 ~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~ll~~~-~~~v~~~a~~~l  493 (531)
T 4TNM_A          421 CDLLTC------PDLKVVTVCLEALENILVVGEAEKNLGHTGEDNLYAQMIDEAEGLEKIENLQSHD-NNDIYDKAVKIL  493 (531)
T ss_pred             HHHccC------CCHHHHHHHHHHHHHHHhhCccchhhcCCCCcHHHHHHHHHCCcHHHHHHHhcCC-CHHHHHHHHHHH
Confidence            888776      36788899999999998531            11223334446788888888776 788999999999


Q NP_000290.2     709 SDMWSSKELQG  719 (747)
Q Consensus       709 snL~~~~~~~~  719 (747)
                      .+++...+...
T Consensus       494 ~~l~~~~~~~~  504 (531)
T 4TNM_A          494 ETFWTEDNEEE  504 (531)
T ss_pred             HHHhcCCCCcc
Confidence            99987655443


No 34
>5TBK_C Importin subunit alpha-3, Regulator of; Nuclear Import, Importin alpha, RCC1; 3.45A {Homo sapiens}
Probab=98.21  E-value=3.4e-10  Score=119.34  Aligned_cols=366  Identities=16%  Similarity=0.161  Sum_probs=222.2  Template_Neff=12.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESA-KQQVYQLGGICKLVDLLRSP-NQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~-~~~li~~~IL~~Ll~lL~s~-d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .+++.+...+.+.++.++..++.+|..++...... ...+...++++.+...+... +..++..++.++..++.......
T Consensus        71 ~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~  150 (521)
T 5TBK_C           71 TSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQT  150 (521)
T ss_dssp             CCSSTHHHHTTSSCHHHHHHHHHHHHHHHHTTTCCCTTSCTTTTHHHHHHHHHHCCSCHHHHHHHHHHHHHHHTSCHHHH
T ss_pred             hcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCCCCCHHHHHHCCcHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCChHHH
Confidence            35566677777777788888999998887643221 12233346677777777643 67788888999988876543333


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDP  400 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~  400 (747)
                      ..+...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.|+.++...               .++
T Consensus       151 ~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~~~  214 (521)
T 5TBK_C          151 QAVVQSNAVPLFLRLLH-SPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPS---------------IPI  214 (521)
T ss_dssp             HHHHTTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHHHHCHHHHHHHHHTTCHHHHHTTCCTT---------------SCH
T ss_pred             HHHHHCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHhCCC---------------CCH
Confidence            33334457777777776 5567888899999999886432 2222333 6677777766532               123


Q NP_000290.2     401 EVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH  480 (747)
Q Consensus       401 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  480 (747)
                      ++...+..+|..-.                     .............+++..|...+..      .+..-...+..+|.
T Consensus       215 ~~~~~a~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~L~  267 (521)
T 5TBK_C          215 TFLRNVTWVMVNLC---------------------RHKDPPPPMETIQEILPALCVLIHH------TDVNILVDTVWALS  267 (521)
T ss_dssp             HHHHHHHHHHHHHH---------------------CCCSSCCCHHHHHHHHHHHHHHTTC------SCHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH---------------------cCCCCCCCHHHHHHHHHHHHHHhhC------CCHHHHHHHHHHHH
Confidence            33333433332211                     0000001111122333333333221      11222223333333


Q NP_000290.2     481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSK  560 (747)
Q Consensus       481 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~  560 (747)
                      ++...-+                                                  .....+.+.++++.++.++. +.
T Consensus       268 ~l~~~~~--------------------------------------------------~~~~~~~~~~~~~~l~~~l~-~~  296 (521)
T 5TBK_C          268 YLTDAGN--------------------------------------------------EQIQMVIDSGIVPHLVPLLS-HQ  296 (521)
T ss_dssp             HHHHHCH--------------------------------------------------HHHHHHHHTTCHHHHGGGGG-CS
T ss_pred             HHhccCh--------------------------------------------------HHHHHHHHCChHHHHHHHhc-CC
Confidence            3321100                                                  01112234567788888887 46


Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVFP  638 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI~  638 (747)
                      ++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++++|.+++... .. ..+...++++
T Consensus       297 ~~~v~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~  371 (521)
T 5TBK_C          297 EVKVQTAALRAVGNIVTGTDE-----QTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVP  371 (521)
T ss_dssp             SHHHHHHHHHHHHHHHTSCHH-----HHHHHHHTTCGGGHHHHHTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHTTTCHH
T ss_pred             CHHHHHHHHHHHHHHHcCCHH-----HHHHHHhCCHHHhHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHH
Confidence            677888899999998875332     2233344578888888888888889999999999998762 22 2334456778


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP-QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~-e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      .|..++.+      .++.++..++.+|.+++.... .....+.+.++++.|..++.+. ++.++..++.+|.+++...+
T Consensus       372 ~l~~~l~~------~~~~v~~~a~~~L~~l~~~~~~~~~~~l~~~~~~~~L~~~l~~~-~~~v~~~a~~~l~~l~~~~~  443 (521)
T 5TBK_C          372 MIIHLLDK------GDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVK-DAQVVQVVLDGLSNILKMAE  443 (521)
T ss_dssp             HHHHHHHH------SCHHHHHHHHHHHHHHHHHSCHHHHHHHHTTTCHHHHHGGGGSS-CHHHHHHHHHHHHHHHHHCS
T ss_pred             HHHHHHHh------CCHHHHHHHHHHHHHHHccCCHHHHHHHHHCCCHHHHHHHcCCC-CHHHHHHHHHHHHHHHHHhH
Confidence            88888776      367788999999999985322 2233344456788888888766 77888999999999887543


No 35
>5TBK_D Importin subunit alpha-3, Regulator of; Nuclear Import, Importin alpha, RCC1; 3.45A {Homo sapiens}
Probab=98.21  E-value=3.4e-10  Score=119.34  Aligned_cols=366  Identities=16%  Similarity=0.161  Sum_probs=221.8  Template_Neff=12.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESA-KQQVYQLGGICKLVDLLRSP-NQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~-~~~li~~~IL~~Ll~lL~s~-d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .+++.+...+.+.++.++..++.+|..++...... ...+...++++.+...+... +..++..++.++..++.......
T Consensus        71 ~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~  150 (521)
T 5TBK_D           71 TSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQT  150 (521)
T ss_dssp             -CCSHHHHHTTSSCHHHHHHHHHHHHTHHHHHHSSCSHHHHHHTHHHHHHHHHHCCSCHHHHHHHHHHHHHHHTSCHHHH
T ss_pred             hcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCCCCCHHHHHHCCcHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCChHHH
Confidence            35566677777777788888999998887643221 12233346677777777643 67788888999988876543333


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDP  400 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~  400 (747)
                      ..+...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.|+.++...               .++
T Consensus       151 ~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~~~  214 (521)
T 5TBK_D          151 QAVVQSNAVPLFLRLLH-SPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPS---------------IPI  214 (521)
T ss_dssp             HHHHTTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHHHHCHHHHHHHHHTCCHHHHHTTCCTT---------------SCH
T ss_pred             HHHHHCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHhCCC---------------CCH
Confidence            33334457777777776 5567888899999999886432 2222333 6677777766532               123


Q NP_000290.2     401 EVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH  480 (747)
Q Consensus       401 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  480 (747)
                      ++...+..+|..-.                     .............+++..|...+..      .+..-...+..+|.
T Consensus       215 ~~~~~a~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~L~  267 (521)
T 5TBK_D          215 TFLRNVTWVMVNLC---------------------RHKDPPPPMETIQEILPALCVLIHH------TDVNILVDTVWALS  267 (521)
T ss_dssp             HHHHHHHHHHHHHH---------------------CCCSSCCCHHHHHHHHHHHHHHTTC------SCHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH---------------------cCCCCCCCHHHHHHHHHHHHHHhhC------CCHHHHHHHHHHHH
Confidence            33333433332211                     0000001111122333333333221      11222223333333


Q NP_000290.2     481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSK  560 (747)
Q Consensus       481 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~  560 (747)
                      ++...-+                                                  .....+.+.++++.++.++. +.
T Consensus       268 ~l~~~~~--------------------------------------------------~~~~~~~~~~~~~~l~~~l~-~~  296 (521)
T 5TBK_D          268 YLTDAGN--------------------------------------------------EQIQMVIDSGIVPHLVPLLS-HQ  296 (521)
T ss_dssp             HHHHHCH--------------------------------------------------HHHHHHHHTTCHHHHGGGGG-CS
T ss_pred             HHhccCh--------------------------------------------------HHHHHHHHCChHHHHHHHhc-CC
Confidence            3321100                                                  01112234567788888887 46


Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVFP  638 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI~  638 (747)
                      ++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++++|.+++... .. ..+...++++
T Consensus       297 ~~~v~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~  371 (521)
T 5TBK_D          297 EVKVQTAALRAVGNIVTGTDE-----QTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVP  371 (521)
T ss_dssp             SHHHHHHHHHHHHHHHTSCHH-----HHHHHHHTTCGGGHHHHHHCSCHHHHHHHHHHHHHHTTSCHHHHHHHHTTTCHH
T ss_pred             CHHHHHHHHHHHHHHHcCCHH-----HHHHHHhCCHHHhHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHH
Confidence            677888899999998875332     2233344578888888888888889999999999998762 22 2334456778


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP-QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~-e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      .|..++.+      .++.++..++.+|.+++.... .....+.+.++++.|..++.+. ++.++..++.+|.+++...+
T Consensus       372 ~l~~~l~~------~~~~v~~~a~~~L~~l~~~~~~~~~~~l~~~~~~~~L~~~l~~~-~~~v~~~a~~~l~~l~~~~~  443 (521)
T 5TBK_D          372 MIIHLLDK------GDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVK-DAQVVQVVLDGLSNILKMAE  443 (521)
T ss_dssp             HHHHHHHH------SCHHHHHHHHHHHHHHHHHSCHHHHHHHHTTTCHHHHHGGGGSS-CHHHHHHHHHHHHHHHHHCS
T ss_pred             HHHHHHHh------CCHHHHHHHHHHHHHHHccCCHHHHHHHHHCCCHHHHHHHcCCC-CHHHHHHHHHHHHHHHHHhH
Confidence            88888776      367788999999999985322 2233344456788888888766 77888999999999887543


No 36
>2Z6G_A B-catenin; Full-Length, Beta-Catenin, CELL ADHESION; 3.4A {Danio rerio}
Probab=98.14  E-value=6.4e-10  Score=126.67  Aligned_cols=381  Identities=19%  Similarity=0.217  Sum_probs=223.9  Template_Neff=10.700

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+..++.+.+..++..++.+|.+++.........+...++++.+..++...+..++..++.+|..++.........
T Consensus       234 ~~i~~L~~lL~~~~~~v~~~al~~L~~l~~~~~~~~~~~~~~~~~~~L~~lL~~~~~~v~~~a~~~L~~l~~~~~~~~~~  313 (780)
T 2Z6G_A          234 GGIPALVNMLGSPVDSVLFHAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLI  313 (780)
T ss_pred             CcHHHHHHHhCCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            34566666776667788888999998887654333333333567777888887777888889999999888644433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      +...+++..++.++....+..++..++.+|..++........+.. ++++.|..++...                ++++.
T Consensus       314 ~~~~~~~~~L~~~l~~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~l~~L~~~l~~~----------------~~~v~  377 (780)
T 2Z6G_A          314 ILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDP----------------SQRLV  377 (780)
T ss_pred             HHHCCcHHHHHHHhCCCCCHHHHHHHHHHHHHHhCCHHHHHHHHHCCHHHHHHHHccCC----------------CHHHH
Confidence            333456777777776223567788888888888765443333333 6677777666531                23343


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..+|+.-..                     ......   ...+++..|...+..      .+..-...+..+|.++.
T Consensus       378 ~~al~~L~~l~~---------------------~~~~~~---~~~~~l~~L~~~l~~------~~~~v~~~a~~~L~~l~  427 (780)
T 2Z6G_A          378 QNCLWTLRNLSD---------------------AATKQE---GMEGLLGTLVQLLGS------DDINVVTCAAGILSNLT  427 (780)
T ss_pred             HHHHHHHHHHhc---------------------CCCCHH---HHcChHHHHHHHhcC------CCHHHHHHHHHHHHHHH
Confidence            344433332110                     000000   012333333333221      01111222222333322


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK-SKKD  562 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s-s~d~  562 (747)
                      ...                                                  ......+...++++.|+..+.. ..++
T Consensus       428 ~~~--------------------------------------------------~~~~~~~~~~~~l~~L~~~l~~~~~~~  457 (780)
T 2Z6G_A          428 CNN--------------------------------------------------YKNKMMVCQVGGIEALVRTVLRAGDRE  457 (780)
T ss_pred             cCC--------------------------------------------------HHHHHHHHHCChHHHHHHHHhcCCCCH
Confidence            110                                                  0001112345667777776652 1456


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEV  640 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~L  640 (747)
                      .++..++.+|.+++.....  .......+...++++.|+.++... ++.++..++.+|.+++..... ..+...++++.|
T Consensus       458 ~v~~~a~~~L~~l~~~~~~--~~~~~~~~~~~~~i~~L~~ll~~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~l~~L  535 (780)
T 2Z6G_A          458 DITEPAICALRHLTSRHQD--AEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRL  535 (780)
T ss_pred             HHHHHHHHHHHHHHcCCcc--HHHHHHHHHHCCcHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCHHHHHHHHhCChHHHH
Confidence            7788899999998865321  000112223456788888888765 577889999999999876333 233455677788


Q NP_000290.2     641 TRLLTSHTGN----------------TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       641 l~LL~s~s~~----------------~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      +.++......                ...+..++..++.+|.+|+.. ......+...++++.|+.++.+. ++.++..+
T Consensus       536 ~~ll~~~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~a~~aL~~L~~~-~~~~~~~~~~~~l~~L~~~l~~~-~~~v~~~a  613 (780)
T 2Z6G_A          536 VQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEACTGALHILARD-IHNRIVIRGLNTIPLFVQLLYSP-IENIQRVA  613 (780)
T ss_pred             HHHhcCCCHHHHHHHHhhhhhhhhhcCCChHHHHHHHHHHHHHHhCC-hhHHHHHHhCCcHHHHHHHhcCC-CHHHHHHH
Confidence            8777652000                000234888999999999864 44444455556788888888776 78899999


Q NP_000290.2     705 RLLLSDMWSSKELQGVLRQQG  725 (747)
Q Consensus       705 L~aLsnL~~~~~~~~~~~~~~  725 (747)
                      +.+|.+++...+....+...|
T Consensus       614 ~~~L~~l~~~~~~~~~~~~~~  634 (780)
T 2Z6G_A          614 AGVLCELAQDKEAAEAIEAEG  634 (780)
T ss_pred             HHHHHHHhcCHHHHHHHHHCC
Confidence            999999997766554444433


No 37
>1JDH_A BETA-CATENIN, hTcf-4; BETA-CATENIN, TCF4, PROTEIN-PROTEIN COMPLEX, TRANSCRIPTION; 1.9A {Homo sapiens} SCOP: a.118.1.1
Probab=98.13  E-value=6.1e-10  Score=114.95  Aligned_cols=326  Identities=17%  Similarity=0.189  Sum_probs=198.8  Template_Neff=13.100

Q NP_000290.2     286 LGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE  365 (747)
Q Consensus       286 ~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~  365 (747)
                      .++++.+...+.+.+..++..++.++..++.............++++.+...+....++.++..++.++..+........
T Consensus        16 ~~~i~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~   95 (529)
T 1JDH_A           16 TRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLL   95 (529)
T ss_dssp             -CHHHHHHHHHTCSCHHHHHHHHHHHHHHHTSHHHHHHHHTCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTSHHHHH
T ss_pred             HhhHHHHHHHhcCCCHHHHHHHHHHHHHHhcCHHHHHHHHhCcchHHHHHHHhhCCCCHHHHHHHHHHHHHHhcCHHHHH
Confidence            45677777778777788888999999888765322211111134667777777533567788899999998876544443


Q NP_000290.2     366 ELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTM  444 (747)
Q Consensus       366 ~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  444 (747)
                      .+.. ++++.|+.++..+                ++++-..+..++..-....                    +..+...
T Consensus        96 ~~~~~~~~~~l~~~l~~~----------------~~~~~~~a~~~l~~l~~~~--------------------~~~~~~~  139 (529)
T 1JDH_A           96 AIFKSGGIPALVKMLGSP----------------VDSVLFYAITTLHNLLLHQ--------------------EGAKMAV  139 (529)
T ss_dssp             HHHHTTHHHHHHHHTTCS----------------CHHHHHHHHHHHHHHHHHC--------------------TTHHHHH
T ss_pred             HHHHcCCHHHHHHHhcCC----------------CHHHHHHHHHHHHHHHcCC--------------------cchHHHH
Confidence            4444 6777777776532                3444444444433211100                    0000100


Q NP_000290.2     445 RNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNN  524 (747)
Q Consensus       445 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  524 (747)
                       .-.++++.|...++.      -+..-...+...|.++...-                                      
T Consensus       140 -~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~--------------------------------------  174 (529)
T 1JDH_A          140 -RLAGGLQKMVALLNK------TNVKFLAITTDCLQILAYGN--------------------------------------  174 (529)
T ss_dssp             -HHHTHHHHHHHGGGC------CCHHHHHHHHHHHHHHHTTC--------------------------------------
T ss_pred             -HHcChHHHHHHHhcC------CCHHHHHHHHHHHHHHhcCC--------------------------------------
Confidence             012444544444332      12222233333333332100                                      


Q NP_000290.2     525 NYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL  604 (747)
Q Consensus       525 ~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL  604 (747)
                                  ......+.+.++++.++.++....++.++..++.+|.+++....      ....+...++++.+..++
T Consensus       175 ------------~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~------~~~~~~~~~~~~~l~~~l  236 (529)
T 1JDH_A          175 ------------QESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSS------NKPAIVEAGGMQALGLHL  236 (529)
T ss_dssp             ------------HHHHHHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTSTT------HHHHHHHTTHHHHHHTTT
T ss_pred             ------------HHHHHHHHHCChhHHHHHHHccCCcHHHHHHHHHHHHHHhcCCc------cHHHHHHCCHHHHHHHHc
Confidence                        01112234566788888888742366788889999999887532      133334567888899988


Q NP_000290.2     605 QSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSM  684 (747)
Q Consensus       605 ~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~gi  684 (747)
                      .+.++.++..++++|.+++......... .++++.+..++.+      .++.++..++.+|.+++...+.....+...+.
T Consensus       237 ~~~~~~~~~~~~~~l~~l~~~~~~~~~~-~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~  309 (529)
T 1JDH_A          237 TDPSQRLVQNCLWTLRNLSDAATKQEGM-EGLLGTLVQLLGS------DDINVVTCAAGILSNLTCNNYKNKMMVCQVGG  309 (529)
T ss_dssp             TSSCHHHHHHHHHHHHHHHTTCTTCSCC-HHHHHHHHHHTTC------SCHHHHHHHHHHHHHHTTTCHHHHHHHHHTTH
T ss_pred             cCCCHHHHHHHHHHHHHHcchhhhHHHH-chHHHHHHHHhCC------CCHHHHHHHHHHHHHHhcCCHHHHHHHHHcCH
Confidence            8888889999999999998763221111 4566777777765      36788899999999998765555555666677


Q NP_000290.2     685 LNNIINLCRS-SASPKAAEAARLLLSDMWSSKEL  717 (747)
Q Consensus       685 L~~Ll~LL~s-~~d~eVr~aAL~aLsnL~~~~~~  717 (747)
                      ++.++..+.. ..++.++..++.+|.+++.....
T Consensus       310 ~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~~  343 (529)
T 1JDH_A          310 IEALVRTVLRAGDREDITEPAICALRHLTSRHQE  343 (529)
T ss_dssp             HHHHHHHHHHHTTCHHHHHHHHHHHHHHTSSSTT
T ss_pred             HHHHHHHHHhcCCChHhHHHHHHHHHHHhcCccc
Confidence            8888876652 12577888999999998866553


No 38
>2Z6H_A Catenin beta-1; Beta-Catenin, C-terminal Domain, Activator, Cell; 2.2A {Homo sapiens}
Probab=98.12  E-value=7.3e-10  Score=121.28  Aligned_cols=378  Identities=20%  Similarity=0.248  Sum_probs=205.2  Template_Neff=11.700

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++.........+...++++.+...+...+..++..++.++..++.........+
T Consensus        99 ~i~~L~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~L~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~  178 (644)
T 2Z6H_A           99 GIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLII  178 (644)
T ss_pred             cHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            45566666766777888899999998876543333333345677778888877778888899999998886444333334


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFF  404 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~  404 (747)
                      ...+++..+...+....+..++..++.++..++........+.. ++++.|..++...                ++++..
T Consensus       179 ~~~~~~~~L~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~l~~l~~~l~~~----------------~~~~~~  242 (644)
T 2Z6H_A          179 LASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDP----------------SQRLVQ  242 (644)
T ss_pred             HHCCcHHHHHHHhcCCCCHHHHHHHHHHHHHHccChHHHHHHHHCCHHHHHHHHhcCC----------------CHHHHH
Confidence            44457777777776333567788888888888765443333333 6666676666532                111222


Q NP_000290.2     405 NATGCLRKRL-----------GMRELLALVPQ-------RATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASR  466 (747)
Q Consensus       405 ~~~~~~~~~~-----------~~~~~~~~~~~-------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  466 (747)
                      .+..+|..-.           .+..++.++..       .+...-.++...+......-.-.+.++.|...+..    ..
T Consensus       243 ~a~~~L~~l~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~l~~L~~~l~~----~~  318 (644)
T 2Z6H_A          243 NCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLR----AG  318 (644)
T ss_pred             HHHHHHHHHhcCCCCHHHHCchHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCHHHHHHHHhCCHHHHHHHHHhc----CC
Confidence            2222221100           01111111110       00000111111111000000112334444333221    01


Q NP_000290.2     467 CDDKSVENCMCVLHNLSYRLDAEV------------PTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEE  534 (747)
Q Consensus       467 ~~~~~~~~~~~~~~~~~~~~~~~~------------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  534 (747)
                      -+..-.+.+...|.++........            +.-.+.+... .+....+....++.+-.                
T Consensus       319 ~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~v~~~a~~~L~~l~----------------  381 (644)
T 2Z6H_A          319 DREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPP-SHWPLIKATVGLIRNLA----------------  381 (644)
T ss_pred             CCHHHHHHHHHHHHHHHcCCCCHHHHHHHHHHCCcHHHHHHHhcCC-CCHHHHHHHHHHHHHHh----------------
Confidence            123345666777777765433210            0000000000 00000011111111111                


Q NP_000290.2     535 TNPKGSGWLYHSDAIRTYLNLMGKSKK----------------------DATLEACAGALQNLTASKGLMSSGMSQLIGL  592 (747)
Q Consensus       535 ~ni~~~~~lve~G~I~~LL~LL~ss~d----------------------~eVr~~AL~aL~nLs~~s~~~s~~~~~~lli  592 (747)
                      ........+.+.++++.|+.++.. ..                      ..++..++.+|.+++.....      ...+.
T Consensus       382 ~~~~~~~~l~~~~~~~~L~~~l~~-~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~a~~~L~~l~~~~~~------~~~~~  454 (644)
T 2Z6H_A          382 LCPANHAPLREQGAIPRLVQLLVR-AHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHN------RIVIR  454 (644)
T ss_pred             cCHHHHHHHHHCCcHHHHHHHHcc-CCHHHHHHHhcCCchhhhhcCCCCHHHHHHHHHHHHHHhcCcch------HHHHH
Confidence            001112234566788888888863 32                      23777888899988865321      22334


Q NP_000290.2     593 KEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       593 e~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                      ..++++.|+.++.+.++.++..++.+|.+++..... ..+...++++.|..++.+      .++.++..++.+|.+++..
T Consensus       455 ~~~~i~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~L~~~l~~------~~~~v~~~a~~~L~~l~~~  528 (644)
T 2Z6H_A          455 GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHS------RNEGVATYAAAVLFRMSED  528 (644)
T ss_pred             HCCcHHHHHHHHhCCCHHHHHHHHHHHHHHhcCHHHHHHHHHCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHhCC
Confidence            457888899989888889999999999999876433 233445778888888876      3678999999999999875


Q NP_000290.2     672 QP  673 (747)
Q Consensus       672 s~  673 (747)
                      .+
T Consensus       529 ~~  530 (644)
T 2Z6H_A          529 KP  530 (644)
T ss_pred             Cc
Confidence            43


No 39
>6SA8_A ring-like DARPin-Armadillo fusion H83_D01, LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG; protein fusion, DARPin, Armadillo, shared; 2.4A {synthetic construct}
Probab=98.11  E-value=7.7e-10  Score=121.20  Aligned_cols=342  Identities=20%  Similarity=0.251  Sum_probs=215.3  Template_Neff=11.900

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.+..++..++..|..++.........+...++++.+..++.+.++.++..++.++..++........
T Consensus       177 ~~~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~  256 (671)
T 6SA8_A          177 KKILKDLVKKLSSPNENELQNALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQ  256 (671)
T ss_dssp             HHHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHH
T ss_pred             HHHHHHHHHhcCCCCHHHHHHHHHHHHHHHcCCcHHHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHH
Confidence            44566677777777778888899999888765433333444456778888888877888899999999988764443333


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPE  401 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~  401 (747)
                      .+...+.++.+...+. +.++.++..++.++..++... .....+.. ++++.|+.++...                +++
T Consensus       257 ~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~L~~~l~~~----------------~~~  319 (671)
T 6SA8_A          257 AVIDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSP----------------NEQ  319 (671)
T ss_dssp             HHHHTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCS----------------CHH
T ss_pred             HHHHcCHHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCcHHHHHHHHhChHHHHHHHhcCC----------------cHH
Confidence            3444567778888876 566788889999999888643 22233333 6777777776531                344


Q NP_000290.2     402 VFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHN  481 (747)
Q Consensus       402 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  481 (747)
                      +-..+..+|..-..      ..+              ..+..+. -.++++.|+..++..      +....+.++..|.+
T Consensus       320 v~~~a~~~L~~l~~------~~~--------------~~~~~~~-~~~~l~~l~~~l~~~------~~~~~~~a~~~L~~  372 (671)
T 6SA8_A          320 ILQEALWALSNIAS------GGN--------------EQIQAVI-DAGALPALVQLLSSP------NEQILQEALWALSN  372 (671)
T ss_dssp             HHHHHHHHHHHHTT------SCH--------------HHHHHHH-HTTHHHHHHHHTTCS------CHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhc------CCc--------------HHHHHHH-hcChHHHHHHHhcCC------CHHHHHHHHHHHHH
Confidence            44444433322110      000              0011111 123444554444321      22333344444444


Q NP_000290.2     482 LSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKK  561 (747)
Q Consensus       482 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d  561 (747)
                      +...-                                                  ......+.+.++++.|+.++. ..+
T Consensus       373 l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~  401 (671)
T 6SA8_A          373 IASGG--------------------------------------------------NEQIQAVIDAGALPALVQLLS-SPN  401 (671)
T ss_dssp             HTTSC--------------------------------------------------HHHHHHHHHTTHHHHHHHGGG-CSC
T ss_pred             HHcCC--------------------------------------------------cHHHHHHHHcCcHHHHHHHhc-CCC
Confidence            43200                                                  001112245567888888887 467


Q NP_000290.2     562 DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL-L-HRVMGNQVFPE  639 (747)
Q Consensus       562 ~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e-~-~~ll~~giI~~  639 (747)
                      +.++..++.+|.+++.....     ....+.+.++++.|+.++.+.++.++..++.+|.+++.... . ..+...++++.
T Consensus       402 ~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~L~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~  476 (671)
T 6SA8_A          402 EQILQEALWALSNIASGGNE-----QIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPA  476 (671)
T ss_dssp             HHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTCHHHHHHGGGCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHH
T ss_pred             HHHHHHHHHHHHhhcCCCHH-----HHHHHHhcCcHHHHHHHcCCCCHHHHHHHHHHHHHHHcCChHHHHHHHhcCcHHH
Confidence            78888999999999875332     23333456788899999988888999999999999996632 2 23345667888


Q NP_000290.2     640 VTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINL  691 (747)
Q Consensus       640 Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~L  691 (747)
                      |..++.+      .++.++..++.+|.+|+...+.....+...+.++.++..
T Consensus       477 l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~ll~~  522 (671)
T 6SA8_A          477 LVQLLSS------PNEQIQDEAEKTLLNIANGSEEQQKAVYDAGALKYLLII  522 (671)
T ss_dssp             HHHHTTC------SCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHH
T ss_pred             HHHHhhC------CCHHHHHHHHHHHHHHHcCCHHHHHHHhcccHHHHHHHH
Confidence            8888876      367889999999999987655555555555555555544


No 40
>4RXH_B Importin subunit alpha, Large T; ARM repeat, NLS, nuclear import; 1.7553A {Neurospora crassa}
Probab=98.05  E-value=1.2e-09  Score=113.39  Aligned_cols=157  Identities=18%  Similarity=0.227  Sum_probs=116.8  Template_Neff=12.500

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++++.++.++. +.++.++..++.+|.+++.....     ....+...++++.+..++.+.++.++..++.+|.+++.
T Consensus       196 ~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~  269 (495)
T 4RXH_B          196 IAPALPVLAKLVY-SLDDEVLIDACWAISYLSDGSND-----KIQAVIEAGIPRRLVELLMHASTSVQTPALRSVGNIVT  269 (495)
T ss_dssp             HTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHTSSCHH-----HHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTT
T ss_pred             hcCHHHHHHHHhh-CCCHHHHHHHHHHHHHHhcCCHH-----HHHHHHHCChHHHHHHHHhcCCccHHHHHHHHHHHHhc
Confidence            3456777888887 46778888999999998864332     22333455788888888888888899999999999987


Q NP_000290.2     625 HP-LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAE  702 (747)
Q Consensus       625 ~~-e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~  702 (747)
                      .. .. ..+...++++.+..++.+      .++.++..++.+|.+++...+.....+...++++.|..++.+. ++.++.
T Consensus       270 ~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~  342 (495)
T 4RXH_B          270 GDDVQTQVIINCGALPCLLSLLSS------NKDGIRKEACWTISNITAGNSAQIQSVIDANIIPPLIHLLSHA-DLKTRK  342 (495)
T ss_dssp             SCHHHHHHHHHTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHHHSS-CHHHHH
T ss_pred             CCHHHHHHHHhCCHHHHHHHHHhC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHHhcC-CHHHHH
Confidence            63 22 233445677888888876      3678899999999999876554444555556788888888766 778899


Q NP_000290.2     703 AARLLLSDMWSS  714 (747)
Q Consensus       703 aAL~aLsnL~~~  714 (747)
                      .++.+|.+++..
T Consensus       343 ~a~~~l~~l~~~  354 (495)
T 4RXH_B          343 EACWAISNATSG  354 (495)
T ss_dssp             HHHHHHHHTTTT
T ss_pred             HHHHHHHHHHhc
Confidence            999999998876


No 41
>5XJG_A Vacuolar protein 8, Nucleus-vacuole junction; Vac8p, Nvj1p, Membrane contact site; HET: B3P, PE5; 2.4A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=98.04  E-value=1.3e-09  Score=111.79  Aligned_cols=133  Identities=20%  Similarity=0.248  Sum_probs=82.5  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+.... .....+...++++.+...+.+.+..++..++.++..++..........
T Consensus       159 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  237 (506)
T 5XJG_A          159 ALIPLTKLAKSKHIRVQRNATGALLNMTHSE-ENRKELVNAGAVPVLVSLLSSTDPDVQYYCTTALSNIAVDEANRKKLA  237 (506)
T ss_dssp             THHHHHHHTTCSSHHHHHHHHHHHHHTCSSH-HHHHHHHHHTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSHHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHcCCH-HHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCHHHHHHHH
Confidence            4555666666667788888899988887542 222233334567777777777777888888998888875433221111


Q NP_000290.2     326 -RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 -l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~  380 (747)
                       ...++++.+...+. ..++.++..++.++..++........+.. ++++.+..++.
T Consensus       238 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~  293 (506)
T 5XJG_A          238 QTEPRLVSKLVSLMD-SPSSRVKCQATLALRNLASDTSYQLEIVRAGGLPHLVKLIQ  293 (506)
T ss_dssp             HHCTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHTTSHHHHHHHHHTTHHHHHHHHHT
T ss_pred             hhChhHHHHHHHHcc-CCCHHHHHHHHHHHHHHhCCChhHHHHHHcCcHHHHHHHHh
Confidence             11235666677775 45667788888888888765433333332 45555555554


No 42
>6KBM_A Vacuolar protein 8, Autophagy-related protein; Armadillo repeats, complex, PROTEIN BINDING-PROTEIN; 2.902A {Saccharomyces cerevisiae}
Probab=98.04  E-value=1.3e-09  Score=111.79  Aligned_cols=133  Identities=20%  Similarity=0.248  Sum_probs=82.5  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+.... .....+...++++.+...+.+.+..++..++.++..++..........
T Consensus       159 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  237 (506)
T 6KBM_A          159 ALIPLTKLAKSKHIRVQRNATGALLNMTHSE-ENRKELVNAGAVPVLVSLLSSTDPDVQYYCTTALSNIAVDEANRKKLA  237 (506)
T ss_dssp             THHHHHHHTTCSSHHHHHHHHHHHHHTCSSH-HHHHHHHHTTCHHHHHHGGGCSCHHHHHHHHHHHHHHTTSHHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHcCCH-HHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCHHHHHHHH
Confidence            4555666666667788888899988887542 222233334567777777777777888888998888875433221111


Q NP_000290.2     326 -RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 -l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~  380 (747)
                       ...++++.+...+. ..++.++..++.++..++........+.. ++++.+..++.
T Consensus       238 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~  293 (506)
T 6KBM_A          238 QTEPRLVSKLVSLMD-SPSSRVKCQATLALRNLASDTSYQLEIVRAGGLPHLVKLIQ  293 (506)
T ss_dssp             HHCTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHHTSHHHHHHHHHTTCHHHHHHHHT
T ss_pred             hhChhHHHHHHHHcc-CCCHHHHHHHHHHHHHHhCCChhHHHHHHcCcHHHHHHHHh
Confidence             11235666677775 45667788888888888765433333332 45555555554


No 43
>4TNM_A Importin-alpha3 / MOS6; armadillo repeat; 2.9A {Arabidopsis thaliana}
Probab=97.99  E-value=2e-09  Score=113.28  Aligned_cols=158  Identities=18%  Similarity=0.255  Sum_probs=115.7  Template_Neff=12.300

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++++.|+.++. +.++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.
T Consensus       243 ~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~  316 (531)
T 4TNM_A          243 TQPALPVLERLVQ-SMDEEVLTDACWALSYLSDNSND-----KIQAVIEAGVVPRLIQLLGHSSPSVLIPALRTIGNIVT  316 (531)
T ss_pred             hcchHHHHHHHhc-CCCHHHHHHHHHHHHHHhCCCHH-----HHHHHHHCChHHHHHHHHhCCCHHHHHHHHHHHHHHHC
Confidence            3456777777777 46777888999999998865332     22333456788889999988888899999999999987


Q NP_000290.2     625 HPLL--HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAE  702 (747)
Q Consensus       625 ~~e~--~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~  702 (747)
                      ....  ......++++.+..++...     .++.++..++.+|.+++...+.....+...++++.|+.++.+. ++.++.
T Consensus       317 ~~~~~~~~~~~~~~~~~l~~~l~~~-----~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~  390 (531)
T 4TNM_A          317 GDDLQTQMVLDQQALPCLLNLLKNN-----YKKSIKKEACWTISNITAGNADQIQAVIDAGIIQSLVWVLQSA-EFEVKK  390 (531)
T ss_pred             CCHHHHHHHHHCCcHHHHHHHhcCC-----CCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCcHHHHHHHhcCC-CHHHHH
Confidence            6322  2333446777888877652     2567888999999999876545555555666788888888765 778888


Q NP_000290.2     703 AARLLLSDMWSS  714 (747)
Q Consensus       703 aAL~aLsnL~~~  714 (747)
                      .++.+|.+++..
T Consensus       391 ~a~~~l~~l~~~  402 (531)
T 4TNM_A          391 EAAWGISNATSG  402 (531)
T ss_pred             HHHHHHHHHHcC
Confidence            899999888864


No 44
>6KBN_A Vacuolar protein 8, Autophagy-related protein; Armadillo repeats, complex, PROTEIN BINDING-PROTEIN; 3.2A {Saccharomyces cerevisiae}
Probab=97.98  E-value=2.1e-09  Score=112.87  Aligned_cols=133  Identities=20%  Similarity=0.248  Sum_probs=86.0  Template_Neff=12.700

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+.... .....+...++++.+...+.+.+..++..++.++..++..........
T Consensus       153 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  231 (563)
T 6KBN_A          153 ALIPLTKLAKSKHIRVQRNATGALLNMTHSE-ENRKELVNAGAVPVLVSLLSSTDPDVQYYCTTALSNIAVDEANRKKLA  231 (563)
T ss_dssp             THHHHHHHTTCSSHHHHHHHHHHHHHTTSSH-HHHHHHHTTTCHHHHHHHTTCSSHHHHHHHHHHHHHHTTSHHHHHHHH
T ss_pred             hHHHHHHHccCCCHHHHHHHHHHHHHHhCCH-HHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHhCCHHHHHHHH
Confidence            4555666666667788888999998887542 222233334577777777777777888899999988876433221111


Q NP_000290.2     326 -RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 -l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~  380 (747)
                       ...++++.+...+. ..++.++..++.++..++........+.. ++++.+..++.
T Consensus       232 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~  287 (563)
T 6KBN_A          232 QTEPRLVSKLVSLMD-SPSSRVKCQATLALRNLASDTSYQLEIVRAGGLPHLVKLIQ  287 (563)
T ss_dssp             HHCSSHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSHHHHHHHHHTTCHHHHHHHHT
T ss_pred             hhchhHHHHHHHHhc-CCCHHHHHHHHHHHHHHhCChhHHHHHHHCCcHHHHHHHHh
Confidence             11236667777775 55677888899999988875443333333 56677776664


No 45
>6KBN_C Vacuolar protein 8, Autophagy-related protein; Armadillo repeats, complex, PROTEIN BINDING-PROTEIN; 3.2A {Saccharomyces cerevisiae}
Probab=97.98  E-value=2.1e-09  Score=112.87  Aligned_cols=133  Identities=20%  Similarity=0.248  Sum_probs=86.0  Template_Neff=12.700

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+.... .....+...++++.+...+.+.+..++..++.++..++..........
T Consensus       153 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  231 (563)
T 6KBN_C          153 ALIPLTKLAKSKHIRVQRNATGALLNMTHSE-ENRKELVNAGAVPVLVSLLSSTDPDVQYYCTTALSNIAVDEANRKKLA  231 (563)
T ss_dssp             CHHHHHHHTTSSSHHHHHHHHHHHHHHTSSH-HHHHHHHTTTCHHHHHHHTTCSSHHHHHHHHHHHHHHTTSHHHHHHHH
T ss_pred             hHHHHHHHccCCCHHHHHHHHHHHHHHhCCH-HHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHhCCHHHHHHHH
Confidence            4555666666667788888999998887542 222233334577777777777777888899999988876433221111


Q NP_000290.2     326 -RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 -l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~  380 (747)
                       ...++++.+...+. ..++.++..++.++..++........+.. ++++.+..++.
T Consensus       232 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~  287 (563)
T 6KBN_C          232 QTEPRLVSKLVSLMD-SPSSRVKCQATLALRNLASDTSYQLEIVRAGGLPHLVKLIQ  287 (563)
T ss_dssp             HSSTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHTTSHHHHHHHHHTTCHHHHHHHTT
T ss_pred             hhchhHHHHHHHHhc-CCCHHHHHHHHHHHHHHhCChhHHHHHHHCCcHHHHHHHHh
Confidence             11236667777775 55677888899999988875443333333 56677776664


No 46
>4EV8_A Catenin beta-1; mouse catenin, CELL ADHESION; HET: URE; 1.9A {Mus musculus}
Probab=97.98  E-value=2.1e-09  Score=111.06  Aligned_cols=323  Identities=18%  Similarity=0.194  Sum_probs=192.8  Template_Neff=13.100

Q NP_000290.2     286 LGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRR-QNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK  364 (747)
Q Consensus       286 ~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~-~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~  364 (747)
                      .++++.+...+.+.++.++..++.++..+....... ..+.. .+++..+...+....++.++..++.++..++......
T Consensus        17 ~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~-~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~   95 (538)
T 4EV8_A           17 TRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASR-HAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGL   95 (538)
T ss_pred             cCcHHHHHHHhcCCCHHHHHHHHHHHHHHhCChhhH-HHHHhCCChHHHHHHHhcCCCCHHHHHHHHHHHHHHcCCHHHH
Confidence            356677777777777888888999998887643322 12222 2466677776653446678888999999887654433


Q NP_000290.2     365 EELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQT  443 (747)
Q Consensus       365 ~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  443 (747)
                      ..+.. ++++.|+.++..+                ++++...+..+|..-...      .              +..++.
T Consensus        96 ~~~~~~~~~~~l~~~l~~~----------------~~~~~~~a~~~l~~l~~~------~--------------~~~~~~  139 (538)
T 4EV8_A           96 LAIFKSGGIPALVKMLGSP----------------VDSVLFYAITTLHNLLLH------Q--------------EGAKMA  139 (538)
T ss_pred             HHHHHCCcHHHHHHHhCCC----------------CHHHHHHHHHHHHHHhCC------C--------------HHHHHH
Confidence            33333 6777777776532                344444444333221100      0              000000


Q NP_000290.2     444 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMN  523 (747)
Q Consensus       444 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  523 (747)
                      . .-.+++..|...++.      -+..-...+...|.++...                                      
T Consensus       140 ~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~--------------------------------------  174 (538)
T 4EV8_A          140 V-RLAGGLQKMVALLNK------TNVKFLAITTDCLQILAYG--------------------------------------  174 (538)
T ss_pred             H-HHCChHHHHHHHhcC------CCHHHHHHHHHHHHHHhcC--------------------------------------
Confidence            0 012444444444332      0112222222233332210                                      


Q NP_000290.2     524 NNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARL  603 (747)
Q Consensus       524 ~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~L  603 (747)
                                  +......+.+.++++.|+.++....+..++..++.+|.+++.....      ...+...++++.+..+
T Consensus       175 ------------~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~l~~~  236 (538)
T 4EV8_A          175 ------------NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSN------KPAIVEAGGMQALGLH  236 (538)
T ss_pred             ------------CHHHHHHHHHCChHHHHHHHHcCCCCHHHHHHHHHHHHHHcCCHHH------HHHHHHCCcHHHHHHH
Confidence                        0011112245667888888887423667788899999988865321      2333456788889999


Q NP_000290.2     604 LQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSS  683 (747)
Q Consensus       604 L~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~g  683 (747)
                      +.+.++.++..++.+|.+++......... .++++.+..++.+      .++.++..++.+|.+++...+.....+...+
T Consensus       237 l~~~~~~~~~~a~~~l~~l~~~~~~~~~~-~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~  309 (538)
T 4EV8_A          237 LTDPSQRLVQNCLWTLRNLSDAATKQEGM-EGLLGTLVQLLGS------DDINVVTCAAGILSNLTCNNYKNKMMVCQVG  309 (538)
T ss_pred             hcCCCHHHHHHHHHHHHHHHcCCCchHHH-cCcHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHHCC
Confidence            98888889999999999998763221111 3466777777765      3678888999999999765555555555666


Q NP_000290.2     684 MLNNIINLCR--SSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       684 iL~~Ll~LL~--s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      .++.++..+.  .. ++.++..++.+|.+++...+
T Consensus       310 ~~~~l~~~l~~~~~-~~~~~~~a~~~l~~l~~~~~  343 (538)
T 4EV8_A          310 GIEALVRTVLRAGD-REDITEPAICALRHLTSRHQ  343 (538)
T ss_pred             cHHHHHHHHhcCCC-CHHHHHHHHHHHHHHHcCCC
Confidence            7777777665  23 56677788888888876554


No 47
>4BPL_A IMPORTIN SUBUNIT ALPHA-1A, NUCLEOPLASMIN NLS; TRANSPORT PROTEIN, NUCLEAR IMPORT, NUCLEAR; 2.3A {ORYZA SATIVA}
Probab=97.98  E-value=2.2e-09  Score=108.63  Aligned_cols=158  Identities=18%  Similarity=0.251  Sum_probs=116.0  Template_Neff=13.000

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++++.|+.++. +.++.++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.
T Consensus       168 ~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~  241 (454)
T 4BPL_A          168 TRPALPALARLIH-SNDEEVLTDACWALSYLSDGTND-----KIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVT  241 (454)
T ss_dssp             HTTHHHHHHHHTT-CCCHHHHHHHHHHHHHHTSSCHH-----HHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHHHHHh-CCCHHHHHHHHHHHHHHhcCChH-----HHHHHHHCCcHHHHHHHhhCCChHHHHHHHHHHHHHhc
Confidence            3456777777777 46777888899999998865332     22333455788888898888888899999999999987


Q NP_000290.2     625 HPL-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAE  702 (747)
Q Consensus       625 ~~e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~  702 (747)
                      ... . ..+...++++.+..++...     .++.++..++.+|.+++...+.....+...++++.|..++.+. ++.++.
T Consensus       242 ~~~~~~~~~~~~~~~~~l~~~l~~~-----~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~  315 (454)
T 4BPL_A          242 GDDAQTQCIIDHQALPCLLSLLTQN-----LKKSIKKEACWTISNITAGNKDQIQAVINAGIIGPLVNLLQTA-EFDIKK  315 (454)
T ss_dssp             SCHHHHHHHHTTTHHHHHHHHHHSS-----CCHHHHHHHHHHHHHHHTSCHHHHHHHHHHTCHHHHHHHHHHS-CHHHHH
T ss_pred             CCHHHHHHHHHCChHHHHHHHHHhc-----CCHHHHHHHHHHHHHHhcCCHHHHHHHHhCCcHHHHHHHhhcC-CHHHHH
Confidence            632 2 2334456777888887652     2577889999999999876555555555666788888888766 778888


Q NP_000290.2     703 AARLLLSDMWSS  714 (747)
Q Consensus       703 aAL~aLsnL~~~  714 (747)
                      .++.+|.+++..
T Consensus       316 ~a~~~l~~l~~~  327 (454)
T 4BPL_A          316 EAAWAISNATSG  327 (454)
T ss_dssp             HHHHHHHHHHHH
T ss_pred             HHHHHHHHHHcC
Confidence            899999888863


No 48
>4PLS_B Arm00010; PEPTIDE BINDING PROTEIN, designed armadillo; HET: CA; 2.35A {synthetic construct}
Probab=97.96  E-value=2.5e-09  Score=100.09  Aligned_cols=112  Identities=25%  Similarity=0.272  Sum_probs=72.2  Template_Neff=13.200

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETR  326 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll  326 (747)
                      ++.+...+.+.++.++..++.++..++...+.....+...++++.+...+.+.++.++..++.++..++.........+.
T Consensus         3 i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~   82 (281)
T 4PLS_B            3 LPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVI   82 (281)
T ss_dssp             HHHHHHTTTCSCHHHHHHHHHHHHHHHTCSHHHHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHHH
T ss_pred             HHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCHHHHHHHH
Confidence            34556666667778888899999888765444333444455777777877777778888888888888754333222333


Q NP_000290.2     327 RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       327 ~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      ..++++.+...+. +.++.++..++.++..++.
T Consensus        83 ~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~  114 (281)
T 4PLS_B           83 DAGALPALVQLLS-SPNEQILQEALWTLGNIAS  114 (281)
T ss_dssp             HTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHTT
T ss_pred             hCCcHHHHHHHcC-CCCHHHHHHHHHHHHHHhc
Confidence            3345566666665 4455666666666666654


No 49
>5Z8H_A Adenomatous polyposis coli protein, Peptide; APC, inhibitor, PROTEIN BINDING-INHIBITOR complex; HET: PHQ, GOL; 1.79A {Homo sapiens}
Probab=97.95  E-value=2.6e-09  Score=104.87  Aligned_cols=123  Identities=24%  Similarity=0.347  Sum_probs=80.3  Template_Neff=12.500

Q NP_000290.2     258 DEKYQAIGAYYIQHTCFQDESAKQQVYQ-LGGICKLVDLLRSPNQNVQQAAAGALRNLVFR-STTNKLETRRQNGIREAV  335 (747)
Q Consensus       258 d~eVr~sAL~aLsnLs~~~~~~~~~li~-~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~-~~~~~~~ll~~~IL~~Ll  335 (747)
                      ++.++..++.++.+++...+.....+.. .++++.+..++...++.++..++.++.+++.. .......+...++++.+.
T Consensus        92 ~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~  171 (339)
T 5Z8H_A           92 SITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALM  171 (339)
T ss_pred             CHHHHHHHHHHHHHHcCCCHHHHHHHHHhcChHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCCHHHHHHHHHCCcHHHHH
Confidence            6778888999999887644443333444 46778888888777788889999999998864 222223333456777777


Q NP_000290.2     336 SLLRRTGNAEIQKQLTGLLWNLSS-TDELKEELIA--DALPVLADRVI  380 (747)
Q Consensus       336 ~lL~ss~d~eVr~~AL~aLsnLas-~~~~~~~Lve--giLe~Lv~LL~  380 (747)
                      ..+....++.++..++.++.+++. .......+..  ++++.++.++.
T Consensus       172 ~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  219 (339)
T 5Z8H_A          172 ECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLT  219 (339)
T ss_pred             HHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHhcChHHHHHHHhc
Confidence            777622466778888888888876 3333323322  45555555554


No 50
>2Z6H_A Catenin beta-1; Beta-Catenin, C-terminal Domain, Activator, Cell; 2.2A {Homo sapiens}
Probab=97.95  E-value=2.8e-09  Score=116.50  Aligned_cols=415  Identities=18%  Similarity=0.223  Sum_probs=234.1  Template_Neff=11.700

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      ++..+...+. ..+..++..++.+|..++.... ....+...++++.+...+.+.+..++..++.++..++.........
T Consensus        57 ~i~~L~~~l~~~~~~~v~~~a~~~L~~l~~~~~-~~~~~~~~~~i~~L~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  135 (644)
T 2Z6H_A           57 MVSAIVRTMQNTNDVETARCTAGTLHNLSHHRE-GLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMA  135 (644)
T ss_pred             hHHHHHHHHcCCCCHHHHHHHHHHHHHHhCCHH-HHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            4455555555 4566778888888888865432 2223334567778888887777888899999999888654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...++++.+...+. ..+..++..++.++..++.... ....+.. ++++.|+.++...               .++++
T Consensus       136 ~~~~~~~~~L~~~l~-~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~L~~~l~~~---------------~~~~~  199 (644)
T 2Z6H_A          136 VRLAGGLQKMVALLN-KTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTY---------------TYEKL  199 (644)
T ss_pred             HHHCChHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhcCC---------------CCHHH
Confidence            333467777877776 5567888889999999886432 2223333 6777777777642               12233


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..++..-..                     .+..+..+ ...+.++.|...+..      .+....++++..|.++
T Consensus       200 ~~~a~~~L~~l~~---------------------~~~~~~~~-~~~~~l~~l~~~l~~------~~~~~~~~a~~~L~~l  251 (644)
T 2Z6H_A          200 LWTTSRVLKVLSV---------------------CSSNKPAI-VEAGGMQALGLHLTD------PSQRLVQNCLWTLRNL  251 (644)
T ss_pred             HHHHHHHHHHHcc---------------------ChHHHHHH-HHCCHHHHHHHHhcC------CCHHHHHHHHHHHHHH
Confidence            3333333321100                     00000000 012334444333321      1334445566666666


Q NP_000290.2     483 SYRLDAE------VPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLM  556 (747)
Q Consensus       483 ~~~~~~~------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL  556 (747)
                      .......      ++.-...+..  .+.-.......++.+               ....+......+.+.++++.|+..+
T Consensus       252 ~~~~~~~~~~~~~~~~l~~~l~~--~~~~v~~~a~~~L~~---------------l~~~~~~~~~~~~~~~~l~~L~~~l  314 (644)
T 2Z6H_A          252 SDAATKQEGMEGLLGTLVQLLGS--DDINVVTCAAGILSN---------------LTCNNYKNKMMVCQVGGIEALVRTV  314 (644)
T ss_pred             hcCCCCHHHHCchHHHHHHHhcC--CCHHHHHHHHHHHHH---------------HhCCCHHHHHHHHhCCHHHHHHHHH
Confidence            5432210      0000000000  000000001111111               0011112223345667888888877


Q NP_000290.2     557 GK-SKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRHPLL-HRVMG  633 (747)
Q Consensus       557 ~s-s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~~e~-~~ll~  633 (747)
                      .. ..++.++..++.+|.+++.....  .......+...++++.|+.++.+. +..++..++.+|.+++..... ..+..
T Consensus       315 ~~~~~~~~v~~~a~~~L~~l~~~~~~--~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~~~a~~~L~~l~~~~~~~~~l~~  392 (644)
T 2Z6H_A          315 LRAGDREDITEPAICALRHLTSRHQE--AEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLRE  392 (644)
T ss_pred             hcCCCCHHHHHHHHHHHHHHHcCCCC--HHHHHHHHHHCCcHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCHHHHHHHHH
Confidence            52 14567788899999999875331  000012223457788888888765 678889999999999876433 23344


Q NP_000290.2     634 NQVFPEVTRLLTSHTGN----------------TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSAS  697 (747)
Q Consensus       634 ~giI~~Ll~LL~s~s~~----------------~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d  697 (747)
                      .++++.|+.++......                ......++..++.+|.+++... .....+...++++.|+.++.+. +
T Consensus       393 ~~~~~~L~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~a~~~L~~l~~~~-~~~~~~~~~~~i~~l~~~l~~~-~  470 (644)
T 2Z6H_A          393 QGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDV-HNRIVIRGLNTIPLFVQLLYSP-I  470 (644)
T ss_pred             CCcHHHHHHHHccCCHHHHHHHhcCCchhhhhcCCCCHHHHHHHHHHHHHHhcCc-chHHHHHHCCcHHHHHHHHhCC-C
Confidence            56777777777652100                0002347788999999998753 3334444556788888888776 7


Q NP_000290.2     698 PKAAEAARLLLSDMWSSKELQGVLRQQGF  726 (747)
Q Consensus       698 ~eVr~aAL~aLsnL~~~~~~~~~~~~~~~  726 (747)
                      +.++..++.+|.+++...+....+...|+
T Consensus       471 ~~v~~~a~~~L~~l~~~~~~~~~~~~~~~  499 (644)
T 2Z6H_A          471 ENIQRVAAGVLCELAQDKEAAEAIEAEGA  499 (644)
T ss_pred             HHHHHHHHHHHHHHhcCHHHHHHHHHCCc
Confidence            88999999999999987766555544443


No 51
>5AEI_B DESIGNED ARMADILLO REPEAT PROTEIN YIIIM5AII; DE NOVO PROTEIN, PROTEIN-PEPTIDE COMPLEX; HET: CA, ACT; 1.83A {SYNTHETIC CONSTRUCT}
Probab=97.94  E-value=2.9e-09  Score=99.92  Aligned_cols=114  Identities=25%  Similarity=0.274  Sum_probs=73.1  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..++...+.....+...++++.+...+.+.++.++..++.++..++.........+
T Consensus         5 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~   84 (286)
T 5AEI_B            5 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV   84 (286)
T ss_dssp             CHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHhCCHHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666677788888999988876544333334444567777777777777888888888888875433322223


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. +.++.++..++.++..++..
T Consensus        85 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  118 (286)
T 5AEI_B           85 IDAGALPALVQLLS-SPNEQILQEALWALSNIASG  118 (286)
T ss_dssp             HHHTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTS
T ss_pred             HHcChHHHHHHHhh-CCCHHHHHHHHHHHHHHhCC
Confidence            33345566666665 44556666677777666643


No 52
>4B8J_A IMPORTIN SUBUNIT ALPHA-1A; TRANSPORT PROTEIN, NUCLEAR LOCALIZATION SIGNAL; 2.001A {ORYZA SATIVA JAPONICA GROUP}
Probab=97.93  E-value=3.2e-09  Score=111.25  Aligned_cols=160  Identities=20%  Similarity=0.243  Sum_probs=114.5  Template_Neff=12.400

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      .+.++++.++..+....++.++..++.+|.+++.....      .......++++.|..++.+.++.++..++.+|.+++
T Consensus       199 ~~~~~l~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~  272 (528)
T 4B8J_A          199 LANGALLPLLAQLNEHTKLSMLRNATWTLSNFCRGKPQ------PSFEQTRPALPALARLIHSNDEEVLTDACWALSYLS  272 (528)
T ss_dssp             HHTTCHHHHHHTCCTTCCHHHHHHHHHHHHHHHCSSSC------CCHHHHTTHHHHHHHHTTCCCHHHHHHHHHHHHHHT
T ss_pred             HHCCcHHHHHHHHccCCCHHHHHHHHHHHHHHhCCCCC------CCHHHHhhHHHHHHHHhcCCCHHHHHHHHHHHHHHh
Confidence            34556777777765334567788899999998865321      222234578888888888888889999999999998


Q NP_000290.2     624 RH-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA  701 (747)
Q Consensus       624 ~~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr  701 (747)
                      .. ... ..+...++++.++.++.+      .++.++..++.+|.+++...+.....+...++++.|+.++.+..+..++
T Consensus       273 ~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~  346 (528)
T 4B8J_A          273 DGTNDKIQAVIEAGVCPRLVELLLH------PSPSVLIPALRTVGNIVTGDDAQTQCIIDHQALPCLLSLLTQNLKKSIK  346 (528)
T ss_dssp             SSCHHHHHHHHHTTCHHHHHHHTTC------SCHHHHHHHHHHHHHHTTSCHHHHHHHHTTTHHHHHHHHHHSCCCHHHH
T ss_pred             cCChHHHHHHHHCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHHhcCCCHHHH
Confidence            76 222 233445677888888776      3678889999999999875454444555556788888887654356788


Q NP_000290.2     702 EAARLLLSDMWSSK  715 (747)
Q Consensus       702 ~aAL~aLsnL~~~~  715 (747)
                      ..++.+|.+++...
T Consensus       347 ~~a~~~l~~l~~~~  360 (528)
T 4B8J_A          347 KEACWTISNITAGN  360 (528)
T ss_dssp             HHHHHHHHHHHTSC
T ss_pred             HHHHHHHHHHHcCC
Confidence            89999999987543


No 53
>4R10_A Protein humpback-2, Cadherin-related hmr-1; armadillo repeat, cell adhesion, phosphorylation; HET: SEP; 2.3A {Caenorhabditis elegans}
Probab=97.89  E-value=4.1e-09  Score=110.79  Aligned_cols=417  Identities=14%  Similarity=0.174  Sum_probs=224.8  Template_Neff=12.700

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.+|..+.... .....+...++++.+...+.+.++.++..++.++..++.........
T Consensus        73 ~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  151 (572)
T 4R10_A           73 SFVEALMAASKSSNVNVRRNAIGALSHMSEQR-GGPLLIFRSGGLAEIIRMLYDSLESVVHYAVTTLRNLLMHVSDSRAQ  151 (572)
T ss_dssp             HHHHHHHHHTTCSCHHHHHHHHHHHHHHTTST-THHHHHHHTTTHHHHHHGGGCSCHHHHHHHHHHHHHHHHHCTHHHHH
T ss_pred             cHHHHHHHHHhCCCHHHHHHHHHHHHHHhcCC-ChHHHHHhCCcHHHHHHHHhCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            44566666676677788888999998887643 22233334567777777777777888899999999887544333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...++++.+...+. ..++.++..++.++..++... .....+.. ++++.+..++...              ..++++
T Consensus       152 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~--------------~~~~~~  216 (572)
T 4R10_A          152 ARALNAVEALTPHLH-KTNPKLLAQVADGLYFLLIDDAPSKITFLSLLGPQILVSILREY--------------SDHRKL  216 (572)
T ss_dssp             HHHTTHHHHHGGGGG-CCCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHHC--------------TTCHHH
T ss_pred             HHHCCHHHHHHHHHh-cCCHHHHHHHHHHHHHHHCCChHHHHHHHhccHHHHHHHHHHHC--------------CCCHHH
Confidence            334467777777776 556788888999999887543 22223333 6777777776521              012333


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..++..-.                     ..+..+..+.. .+.++.+...+...     -+..-...++.+|.++
T Consensus       217 ~~~a~~~l~~l~---------------------~~~~~~~~~~~-~~~~~~l~~~l~~~-----~~~~~~~~a~~~l~~l  269 (572)
T 4R10_A          217 IYTVVRCIRSLS---------------------VCPSNKPALIS-LGCLPALYVELCTA-----KDERSQTAILVAMRNL  269 (572)
T ss_dssp             HHHHHHHHHHHT---------------------TSTTHHHHHHH-TTHHHHHHHHHTTC-----CSHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHh---------------------cCcchHHHHHh-CCcHHHHHHHHhcC-----CCHHHHHHHHHHHHHH
Confidence            333333332110                     00000111110 12222222211110     1223334445555555


Q NP_000290.2     483 SYRLDAE------VPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLM  556 (747)
Q Consensus       483 ~~~~~~~------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL  556 (747)
                      ....+..      ++.-...+.  ..+.........++.+-               ...+......+.+.++++.|+.++
T Consensus       270 ~~~~~~~~~~~~~~~~l~~~l~--~~~~~~~~~a~~~l~~l---------------~~~~~~~~~~~~~~~~~~~l~~~l  332 (572)
T 4R10_A          270 SDSATNEENLTQLIIKLLEIIR--VANDGMTACACGTLSNL---------------TCNNTRNKQTVCSHGGIDALVTAI  332 (572)
T ss_dssp             GGGCTTCSCCHHHHHHHHHHHH--HCCHHHHHHHHHHHHHH---------------TSSCHHHHHHHHHTTHHHHHHHHH
T ss_pred             cCChHHHHHHHHHHHHHHHHhc--CCCHHHHHHHHHHHHHH---------------HcCCHHHHHHHHHCcHHHHHHHHH
Confidence            4322110      000000000  00000001111111111               111112233345778888898888


Q NP_000290.2     557 GK-SKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMG-  633 (747)
Q Consensus       557 ~s-s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~-  633 (747)
                      .. ..++.++..++++|.+++..... ... ....+...++++.+..++.+.+..++..++.+|.+++..... ..+.. 
T Consensus       333 ~~~~~~~~~~~~a~~~l~~l~~~~~~-~~~-~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~  410 (572)
T 4R10_A          333 RRLPEVEEVTEPALCALRHCTARHSL-AEE-AQSELRFCQAFPVILDQLETLRTPVIKAALGVIRNSALLQTNLIELTQE  410 (572)
T ss_dssp             HHSTTCHHHHHHHHHHHHHHTSSSTT-HHH-HHHHHHHTTHHHHHHHHHTTCCHHHHHHHHHHHHHHHTSHHHHHHHHHC
T ss_pred             HhCCCcHHHHHHHHHHHHHhhccCCC-cHH-HHHHHhhCChHHHHHHHHhcCCHHHHHHHHHHHHHHhccchhHHHHHHH
Confidence            62 23446888999999999432110 000 122233467888889998888888999999999999876332 22222 


Q NP_000290.2     634 -----NQVFPEVTRLLTSHTG----------NTSNSEDILSSACYTVRNLMASQPQLAKQYFSS----------SMLNNI  688 (747)
Q Consensus       634 -----~giI~~Ll~LL~s~s~----------~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~----------giL~~L  688 (747)
                           .++++.+..++.....          ....++.++..++.+|.+++.. +.....+...          ++++.|
T Consensus       411 ~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~-~~~~~~~~~~~~~~~~~~~~~~~~~l  489 (572)
T 4R10_A          411 QTANGHTAVSLTMDILRRAITAIEENPDIAVDGVPMWGVIEGAVSALHQLANH-PAVAAACCDDIGQVGNPECPPFLDLL  489 (572)
T ss_dssp             CCTTCCCHHHHHHHHHHHHHHHHHHCTTCEETTEEHHHHHHHHHHHHHHHTTS-HHHHHHHHHCCCCTTCTTSCCHHHHH
T ss_pred             hhhCCCCcHHHHHHHHHHHHHhcccCcchhccCccHHHHHHHHHHHHHHHhCC-HHHHHHHhccccCCCCCCCccHHHHH
Confidence                 2344555555432000          0012356777888899988764 3333333332          567777


Q NP_000290.2     689 INLC------RSSASPKAAEAARLLLSDMWSSKELQGVLRQQG  725 (747)
Q Consensus       689 l~LL------~s~~d~eVr~aAL~aLsnL~~~~~~~~~~~~~~  725 (747)
                      ..++      ... ++.++..++.+|.+++...+....+...|
T Consensus       490 ~~~l~~~~~~~~~-~~~v~~~a~~~l~~l~~~~~~~~~~~~~~  531 (572)
T 4R10_A          490 HRLLAHPRLGSMD-DEVLEREILGLLYQLSKRPDGARAVESTG  531 (572)
T ss_dssp             HHHHHSHHHHSCS-CSHHHHHHHHHHHHHTSSHHHHHHHHTTT
T ss_pred             HHHHhCcccCCCC-hHHHHHHHHHHHHHHhcCCchhhHHHHcC
Confidence            7777      444 77899999999999998766544443333


No 54
>5XJG_A Vacuolar protein 8, Nucleus-vacuole junction; Vac8p, Nvj1p, Membrane contact site; HET: B3P, PE5; 2.4A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=97.89  E-value=4.2e-09  Score=107.74  Aligned_cols=359  Identities=22%  Similarity=0.262  Sum_probs=200.2  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+.......    ...++++.+...+.+.++.++..++.++..++..... ....
T Consensus        39 ~~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~----~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~-~~~~  113 (506)
T 5XJG_A           39 PLKALTTLVYSDNLNLQRSAALAFAEITEKYVRQ----VSREVLEPILILLQSQDPQIQVAACAALGNLAVNNEN-KLLI  113 (506)
T ss_dssp             HHHHHHHHHTTCCHHHHHHHHHHHHHHHHHCCCC----CCHHHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSHHH-HHHH
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHHhchHHH----HhhccHHHHHHHhhCCCHHHHHHHHHHHHHHHcCchh-HHHH
Confidence            4455555666666777777777777776532211    1234566666666666667777777777777654321 1222


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFF  404 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~  404 (747)
                      ...++++.+...+. +.++.++..++.++..++........+.. ++++.+..++...                ++++-.
T Consensus       114 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~~~  176 (506)
T 5XJG_A          114 VEMGGLEPLINQMM-GDNVEVQCNAVGCITNLATRDDNKHKIATSGALIPLTKLAKSK----------------HIRVQR  176 (506)
T ss_dssp             HHTTTHHHHHHHHT-SSCHHHHHHHHHHHHHHTTSHHHHHHHHTTTTHHHHHHHTTCS----------------SHHHHH
T ss_pred             HhcCcHHHHHHHhh-CCCHHHHHHHHHHHHHHhcCcchhhHHHhcccHHHHHHHccCC----------------CHHHHH
Confidence            23345666666665 45566777777777777654332222222 4555555555421                223322


Q NP_000290.2     405 NATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSY  484 (747)
Q Consensus       405 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  484 (747)
                      .+..++..-         .            .....+..+. ..+.++.+...++.      .+..-...+...|.++..
T Consensus       177 ~a~~~l~~l---------~------------~~~~~~~~~~-~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~  228 (506)
T 5XJG_A          177 NATGALLNM---------T------------HSEENRKELV-NAGAVPVLVSLLSS------TDPDVQYYCTTALSNIAV  228 (506)
T ss_dssp             HHHHHHHHT---------C------------SSHHHHHHHH-HHTHHHHHHHHTTC------SCHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHH---------c------------CCHHHHHHHH-HCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHhc
Confidence            222222210         0            0000000000 02333333333221      011222223333333221


Q NP_000290.2     485 RLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDAT  564 (747)
Q Consensus       485 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eV  564 (747)
                      ..+                                                . .........++++.++.++. ..++.+
T Consensus       229 ~~~------------------------------------------------~-~~~~~~~~~~~~~~l~~~l~-~~~~~~  258 (506)
T 5XJG_A          229 DEA------------------------------------------------N-RKKLAQTEPRLVSKLVSLMD-SPSSRV  258 (506)
T ss_dssp             SHH------------------------------------------------H-HHHHHHHCTTHHHHHHHHTT-CSSHHH
T ss_pred             CHH------------------------------------------------H-HHHHHhhChhHHHHHHHHcc-CCCHHH
Confidence            000                                                0 00000012346777888887 466778


Q NP_000290.2     565 LEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRL  643 (747)
Q Consensus       565 r~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~L  643 (747)
                      +..++.+|.+++.....      ...+...++++.+..++.+.++.++..++.+|.+++..... ......++++.+..+
T Consensus       259 ~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~  332 (506)
T 5XJG_A          259 KCQATLALRNLASDTSY------QLEIVRAGGLPHLVKLIQSDSIPLVLASVACIRNISIHPLNEGLIVDAGFLKPLVRL  332 (506)
T ss_dssp             HHHHHHHHHHHTTSHHH------HHHHHHTTHHHHHHHHHTCSSHHHHHHHHHHHHHHTTSGGGHHHHHHTTCHHHHHHG
T ss_pred             HHHHHHHHHHHhCCChh------HHHHHHcCcHHHHHHHHhCCCHHHHHHHHHHHHHHhcCcchHHHHHHCCcHHHHHHH
Confidence            88899999998875321      22334567888888888888888999999999999876433 233445677788888


Q NP_000290.2     644 LTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       644 L~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      +...     .++.++..++++|.+++...+.....+...++++.+..++.+. ++.++..++.++..+....+
T Consensus       333 l~~~-----~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~l~~l~~~~~  399 (506)
T 5XJG_A          333 LDYK-----DSEEIQCHAVSTLRNLAASSEKNRKEFFESGAVEKCKELALDS-PVSVQSEISACFAILALADV  399 (506)
T ss_dssp             GGCT-----TCHHHHHHHHHHHHHTSSCCHHHHHHHHTTTHHHHHHHHTTSS-CHHHHHHHHHHHHHHTTCHH
T ss_pred             HcCC-----CCHHHHHHHHHHHHHHhcCCHHHHHHHHhCChhHHHHHHHhcC-CHHHHHHHHHHHHHHhccch
Confidence            7652     2467888999999999875544444555556677777777655 56677777777776665443


No 55
>6KBM_A Vacuolar protein 8, Autophagy-related protein; Armadillo repeats, complex, PROTEIN BINDING-PROTEIN; 2.902A {Saccharomyces cerevisiae}
Probab=97.89  E-value=4.2e-09  Score=107.74  Aligned_cols=359  Identities=22%  Similarity=0.262  Sum_probs=200.2  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+.......    ...++++.+...+.+.++.++..++.++..++..... ....
T Consensus        39 ~~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~----~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~-~~~~  113 (506)
T 6KBM_A           39 PLKALTTLVYSDNLNLQRSAALAFAEITEKYVRQ----VSREVLEPILILLQSQDPQIQVAACAALGNLAVNNEN-KLLI  113 (506)
T ss_dssp             HHHHHHHHHHCSCHHHHHHHHHHHHHHHHHCCCC----CCHHHHHHHHHHTTCCCHHHHHHHHHHHHHHTTSHHH-HHHH
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHHhchHHH----HhhccHHHHHHHhhCCCHHHHHHHHHHHHHHHcCchh-HHHH
Confidence            4455555666666777777777777776532211    1234566666666666667777777777777654321 1222


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFF  404 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~  404 (747)
                      ...++++.+...+. +.++.++..++.++..++........+.. ++++.+..++...                ++++-.
T Consensus       114 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~~~  176 (506)
T 6KBM_A          114 VEMGGLEPLINQMM-GDNVEVQCNAVGCITNLATRDDNKHKIATSGALIPLTKLAKSK----------------HIRVQR  176 (506)
T ss_dssp             HHTTTHHHHHHHHT-SCCHHHHHHHHHHHHHHTTSHHHHHHHHTTTTHHHHHHHTTCS----------------SHHHHH
T ss_pred             HhcCcHHHHHHHhh-CCCHHHHHHHHHHHHHHhcCcchhhHHHhcccHHHHHHHccCC----------------CHHHHH
Confidence            23345666666665 45566777777777777654332222222 4555555555421                223322


Q NP_000290.2     405 NATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSY  484 (747)
Q Consensus       405 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  484 (747)
                      .+..++..-         .            .....+..+. ..+.++.+...++.      .+..-...+...|.++..
T Consensus       177 ~a~~~l~~l---------~------------~~~~~~~~~~-~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~  228 (506)
T 6KBM_A          177 NATGALLNM---------T------------HSEENRKELV-NAGAVPVLVSLLSS------TDPDVQYYCTTALSNIAV  228 (506)
T ss_dssp             HHHHHHHHT---------C------------SSHHHHHHHH-HTTCHHHHHHGGGC------SCHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHH---------c------------CCHHHHHHHH-HCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHhc
Confidence            222222210         0            0000000000 02333333333221      011222223333333221


Q NP_000290.2     485 RLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDAT  564 (747)
Q Consensus       485 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eV  564 (747)
                      ..+                                                . .........++++.++.++. ..++.+
T Consensus       229 ~~~------------------------------------------------~-~~~~~~~~~~~~~~l~~~l~-~~~~~~  258 (506)
T 6KBM_A          229 DEA------------------------------------------------N-RKKLAQTEPRLVSKLVSLMD-SPSSRV  258 (506)
T ss_dssp             SHH------------------------------------------------H-HHHHHHHCTTHHHHHHHHTT-CSSHHH
T ss_pred             CHH------------------------------------------------H-HHHHHhhChhHHHHHHHHcc-CCCHHH
Confidence            000                                                0 00000012346777888887 466778


Q NP_000290.2     565 LEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRL  643 (747)
Q Consensus       565 r~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~L  643 (747)
                      +..++.+|.+++.....      ...+...++++.+..++.+.++.++..++.+|.+++..... ......++++.+..+
T Consensus       259 ~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~  332 (506)
T 6KBM_A          259 KCQATLALRNLASDTSY------QLEIVRAGGLPHLVKLIQSDSIPLVLASVACIRNISIHPLNEGLIVDAGFLKPLVRL  332 (506)
T ss_dssp             HHHHHHHHHHHHTSHHH------HHHHHHTTCHHHHHHHHTSSCHHHHHHHHHHHHHHTTSGGGHHHHHHTTCHHHHHHH
T ss_pred             HHHHHHHHHHHhCCChh------HHHHHHcCcHHHHHHHHhCCCHHHHHHHHHHHHHHhcCcchHHHHHHCCcHHHHHHH
Confidence            88899999998875321      22334567888888888888888999999999999876433 233445677788888


Q NP_000290.2     644 LTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       644 L~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      +...     .++.++..++++|.+++...+.....+...++++.+..++.+. ++.++..++.++..+....+
T Consensus       333 l~~~-----~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~l~~l~~~~~  399 (506)
T 6KBM_A          333 LDYK-----DSEEIQCHAVSTLRNLAASSEKNRKEFFESGAVEKCKELALDS-PVSVQSEISACFAILALADV  399 (506)
T ss_dssp             TTCC-----SCHHHHHHHHHHHHHHHHHCSSTHHHHHHTTHHHHHHHHSSSS-CHHHHHHHHHHHHHHTTCHH
T ss_pred             HcCC-----CCHHHHHHHHHHHHHHhcCCHHHHHHHHhCChhHHHHHHHhcC-CHHHHHHHHHHHHHHhccch
Confidence            7652     2467888999999999875544444555556677777777655 56677777777776665443


No 56
>5IZA_A Adenomatous polyposis coli protein, ACE-GLY-GLY-GLU-ALA-LEU-ALA-TRP-NH2; APC, ASEF, Colon CANCER, Drug; 1.5A {Homo sapiens}
Probab=97.89  E-value=4.5e-09  Score=105.07  Aligned_cols=297  Identities=19%  Similarity=0.226  Sum_probs=180.6  Template_Neff=12.000

Q NP_000290.2     236 CSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP-----------NQNVQ  304 (747)
Q Consensus       236 ~~~~~~~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~-----------d~eVr  304 (747)
                      |.+-++..+.........+.+.++.++..++.+|.++... ......+...++++.+..++...           +..++
T Consensus        23 ~~~~~~~~~~~~~~~~~~l~~~~~~~~~~a~~~L~~l~~~-~~~~~~~~~~~~~~~L~~~l~~~~~~~~~~~~~~~~~~~  101 (354)
T 5IZA_A           23 CWEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFD-EEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSITLR  101 (354)
T ss_dssp             HHHHHHHCCTTCCTTTSCCCCGGGGTHHHHHHHHHHHTTS-HHHHHHHHHTTHHHHHHHHHHHHHHHHCSCCCHHHHHHH
T ss_pred             HHHHHHhcCCCCCCCCCCCCCCchHhHHHHHHHHHHccCC-HHHHHHHHHcCHHHHHHHHHHhhHHHhCCCCCCCCHHHH
Confidence            3343444444444445556667778888899999998765 33333344456777777777643           67788


Q NP_000290.2     305 QAAAGALRNLVFRSTTNKLETRR-QNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST--DELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       305 ~~AL~aLs~La~~~~~~~~~ll~-~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~--~~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ..++.++.+++.........+.. .++++.+..++. ..++.++..++.++.+++..  ......+.. ++++.|+.++.
T Consensus       102 ~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  180 (354)
T 5IZA_A          102 RYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLK-SESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECAL  180 (354)
T ss_dssp             HHHHHHHHHHHTTCHHHHHHHHHCHHHHHHHHHGGG-CSCHHHHHHHHHHHHHHHTTCCHHHHHHHHHTTHHHHHHHHHH
T ss_pred             HHHHHHHHHHhcCCHHHHHHHHccchHHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCCChhHHHHHHHCCHHHHHHHHHH
Confidence            88999999887644333333333 467777888886 55678888999999999874  222333444 77777877775


Q NP_000290.2     381 IPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSA-DAGRQTMRNYSGLIDSLMAYVQ  459 (747)
Q Consensus       381 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~  459 (747)
                      ..               .++++...+..+|..                     +... +..++.+..-.|.++.|...+.
T Consensus       181 ~~---------------~~~~~~~~a~~~L~~---------------------l~~~~~~~~~~~~~~~~~~~~l~~~l~  224 (354)
T 5IZA_A          181 EV---------------KKESTLKSVLSALWN---------------------LSAHCTENKADICAVDGALAFLVGTLT  224 (354)
T ss_dssp             HC---------------CCHHHHHHHHHHHHH---------------------HHTTCHHHHHHHHTSTTHHHHHHHHTC
T ss_pred             hc---------------CCHHHHHHHHHHHHH---------------------HHcCChHhHHHHHhhccHHHHHHHHHh
Confidence            42               133443333333322                     1111 1122222221345555555444


Q NP_000290.2     460 NCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKG  539 (747)
Q Consensus       460 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~  539 (747)
                      ...  ...+..-.+.+..+|.+++..+.                                               .+...
T Consensus       225 ~~~--~~~~~~~~~~~~~~L~~l~~~~~-----------------------------------------------~~~~~  255 (354)
T 5IZA_A          225 YRS--QTNTLAIIESGGGILRNVSSLIA-----------------------------------------------TNEDH  255 (354)
T ss_dssp             SSC--SSCCHHHHHHHHHHHHHHHHHHT-----------------------------------------------TCHHH
T ss_pred             hcC--CCCcHHHHHHHHHHHHHHHHHhc-----------------------------------------------CCHHH
Confidence            210  11113334555556666541100                                               01112


Q NP_000290.2     540 SGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLL  619 (747)
Q Consensus       540 ~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aL  619 (747)
                      ...+.+.++++.|+.++. ..++.++..++.+|.+++...+.     ....+.+.++++.|+.++.+.++.++..++.+|
T Consensus       256 ~~~l~~~~~~~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L  329 (354)
T 5IZA_A          256 RQILRENNCLQTLLQHLK-SHSLTIVSNACGTLWNLSARNPK-----DQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL  329 (354)
T ss_dssp             HHHHHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTSSCHH-----HHHHHHHTTHHHHHHTTTTCSSHHHHHHHHHHH
T ss_pred             HHHHHHCCHHHHHHHHhh-cCCHHHHHHHHHHHHHHHccCHH-----HHHHHHhCCHHHHHHHHHhccCHHHHHHHHHHH
Confidence            223356678888988887 46777888999999999874332     233445678899999999888888999999999


Q NP_000290.2     620 SNMSRH  625 (747)
Q Consensus       620 snLa~~  625 (747)
                      .+++..
T Consensus       330 ~~l~~~  335 (354)
T 5IZA_A          330 RNLMAN  335 (354)
T ss_dssp             HHHHHT
T ss_pred             HHHHcc
Confidence            999876


No 57
>4R0Z_A Protein humpback-2; armadillo repeat, cell adhesion; 2.005A {Caenorhabditis elegans}
Probab=97.86  E-value=5.4e-09  Score=112.30  Aligned_cols=401  Identities=14%  Similarity=0.143  Sum_probs=217.2  Template_Neff=12.300

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++.+++.........+...++++.+..++...+..++..++.++..++.........+
T Consensus       115 ~i~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~  194 (629)
T 4R0Z_A          115 GLAEIIRMLYDSLESVVHYAVTTLRNLLMHVSDSRAQARALNAVEALTPHLHKTNPKLLAQVADGLYFLLIDDAPSKITF  194 (629)
T ss_dssp             CHHHHHHGGGCSCHHHHHHHHHHHHHHHHHCTTHHHHHHHTTHHHHHGGGGGCCCHHHHHHHHHHHHHHHTTCHHHHHHH
T ss_pred             cHHHHHHHHhCCCHHHHHHHHHHHHHHHcCChHHHHHHHHCCHHHHHHHHHhccCHHHHHHHHHHHHHHhCCCHHHHHHH
Confidence            45556666666677888889999998866543333344445677888888877778888999999999875544333334


Q NP_000290.2     326 RRQNGIREAVSLLRR-TGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       326 l~~~IL~~Ll~lL~s-s~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ...+++..+..++.. ..+..++..++.++..++........+.. +++..++..+...               .++++.
T Consensus       195 ~~~~~~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~~~~~~  259 (629)
T 4R0Z_A          195 LSLLGPQILVSILREYSDHRKLIYTVVRCIRSLSVCPSNKPALISLGCLPALYVELCTA---------------KDERSQ  259 (629)
T ss_dssp             HHTTHHHHHHHHHHHCTTCHHHHHHHHHHHHHHTTSTTHHHHHHHTTHHHHHHHHHHHC---------------CCHHHH
T ss_pred             HHccHHHHHHHHHHHcCCCHHHHHHHHHHHHHHhcCcchHHHHHHCChHHHHHHHHHhC---------------CCHHHH
Confidence            444567777777651 23456777888888888765443333333 5555554444321               123333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-..-                     +..++.+   .+++..+...+..      -+......+...|.++.
T Consensus       260 ~~a~~~l~~l~~~---------------------~~~~~~~---~~~i~~l~~~l~~------~~~~~~~~a~~~l~~l~  309 (629)
T 4R0Z_A          260 TAILVAMRNLSDS---------------------ATNEENL---TQLIIKLLEIIRV------ANDGMTACACGTLSNLT  309 (629)
T ss_dssp             HHHHHHHHHHGGG---------------------CCTTSCC---HHHHHHHHHHTTT------CCHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHcCC---------------------cchHHHH---HHHHHHHHHHHhc------CCHHHHHHHHHHHHHHH
Confidence            3333333221110                     0001111   1123333322211      12222333444444444


Q NP_000290.2     484 YRLDAEVP---------TRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLN  554 (747)
Q Consensus       484 ~~~~~~~~---------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~  554 (747)
                      ..-+....         .-..-+.....+.........+..+-...            ..........+.+.++++.|+.
T Consensus       310 ~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~------------~~~~~~~~~~~~~~~~~~~l~~  377 (629)
T 4R0Z_A          310 CNNTRNKQTVCSHGGIDALVTAIRRLPEVEEVTEPALCALRHCTAR------------HSLAEEAQSELRFCQAFPVILD  377 (629)
T ss_dssp             TTCHHHHHHHHHTTHHHHHHHHHHHCTTCHHHHHHHHHHHHHHTSS------------STTHHHHHHHHHHTTCHHHHHH
T ss_pred             cCCHHHHHHHHHCCHHHHHHHHHHhCCCcHHHHHHHHHHHHHhccc------------CCCcHHHHHHHhhcChHHHHHH
Confidence            22111000         00000000000000000011111110000            0001111222345677888888


Q NP_000290.2     555 LMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLK------EKGLPQIARLLQS----------------GNSDVV  612 (747)
Q Consensus       555 LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie------~giI~~Ll~LL~s----------------~d~eVr  612 (747)
                      ++. +.++.++..++.+|.+++.....      ...+..      .+.++.+..++..                .+..++
T Consensus       378 ~l~-~~~~~~~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~  450 (629)
T 4R0Z_A          378 QLE-TLRTPVIKAALGVIRNSALLQTN------LIELTQEQTANGHTAVSLTMDILRRAITAIEENPDIAVDGVPMWGVI  450 (629)
T ss_dssp             HHT-TCCHHHHHHHHHHHHHHTTSTTH------HHHHHHCCCTTCCCHHHHHHHHHHHHHHHHHHCTTCEETTEEHHHHH
T ss_pred             HHh-cCCHHHHHHHHHHHHHHcccchh------HHHHHhccccCCccHHHHHHHHHHHHHHhcccCCCcccCCeeHHHHH
Confidence            887 46778888999999998865321      111122      3456666666643                234566


Q NP_000290.2     613 RSGASLLSNMSRHPLL-HRVMGN----------QVFPEVTRLLT------SHTGNTSNSEDILSSACYTVRNLMASQPQL  675 (747)
Q Consensus       613 ~~AL~aLsnLa~~~e~-~~ll~~----------giI~~Ll~LL~------s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~  675 (747)
                      ..++.+|.+++..... ..+...          ++++.+..++.      .      .++.++..++.+|.+++.. +..
T Consensus       451 ~~~~~~L~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~------~~~~v~~~a~~~L~~l~~~-~~~  523 (629)
T 4R0Z_A          451 EGAVSALHQLANHPAVAAACCDDIGQVGNPECPPFLDLLHRLLAHPRLGSM------DDEVLEREILGLLYQLSKR-PDG  523 (629)
T ss_dssp             HHHHHHHHHHTTSHHHHHHHHHCCCCTTCTTSCCHHHHHHHHHTCHHHHTC------SCSHHHHHHHHHHHHHTSS-HHH
T ss_pred             HHHHHHHHHHhCCHHHHHHHhhccccCCCCCCCcHHHHHHHHhcCcccCCC------chHHHHHHHHHHHHHHhcC-CCh
Confidence            7778888888765333 222222          56777777775      3      3678889999999999854 445


Q NP_000290.2     676 AKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQ  718 (747)
Q Consensus       676 ~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~~~  718 (747)
                      ...+...++++.|..++.+. ++.++..++.+|.++..+....
T Consensus       524 ~~~l~~~~~~~~L~~~l~~~-~~~v~~~a~~~L~~l~~~~~~~  565 (629)
T 4R0Z_A          524 ARAVESTGVSALLMESRGSQ-YKSVVTYANGVLSNLKRGDSAA  565 (629)
T ss_dssp             HHHHHTTTCHHHHHHHTTCS-SHHHHHHHHHHHHHHHHHHC--
T ss_pred             HhHHhhccHHHHHHHHhccC-ChhHHHHHHHHHhhccCCChhh
Confidence            55555666788888888766 7888999999999988766553


No 58
>4R0Z_A Protein humpback-2; armadillo repeat, cell adhesion; 2.005A {Caenorhabditis elegans}
Probab=97.85  E-value=5.5e-09  Score=112.24  Aligned_cols=418  Identities=14%  Similarity=0.170  Sum_probs=229.8  Template_Neff=12.300

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.+..++..++.+|..+.... .....+...++++.+...+.+.+..++..++.++.+++.........
T Consensus        73 ~~~~~L~~~l~~~~~~~~~~a~~~L~~l~~~~-~~~~~~~~~~~i~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  151 (629)
T 4R0Z_A           73 SFVEALMAASKSSNVNVRRNAIGALSHMSEQR-GGPLLIFRSGGLAEIIRMLYDSLESVVHYAVTTLRNLLMHVSDSRAQ  151 (629)
T ss_dssp             HHHHHHHHHTTCSCHHHHHHHHHHHHHHTTST-THHHHHHHHTCHHHHHHGGGCSCHHHHHHHHHHHHHHHHHCTTHHHH
T ss_pred             cHHHHHHHHHhCCCHHHHHHHHHHHHHHhcCC-CchHHHHhCCcHHHHHHHHhCCCHHHHHHHHHHHHHHHcCChHHHHH
Confidence            45566666676677888889999999887643 22233334467777888887777788889999999887544333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...++++.+..++. ..++.++..++.++.+++... .....+.. ++++.|+.++...              ..++++
T Consensus       152 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~--------------~~~~~~  216 (629)
T 4R0Z_A          152 ARALNAVEALTPHLH-KTNPKLLAQVADGLYFLLIDDAPSKITFLSLLGPQILVSILREY--------------SDHRKL  216 (629)
T ss_dssp             HHHTTHHHHHGGGGG-CCCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHHC--------------TTCHHH
T ss_pred             HHHCCHHHHHHHHHh-ccCHHHHHHHHHHHHHHhCCCHHHHHHHHHccHHHHHHHHHHHc--------------CCCHHH
Confidence            444467777888776 556788889999999987543 22333333 6777777777621              012233


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..+|..-..                     .+..+..+.. .+.+..++..+...     .+..-...++..|.++
T Consensus       217 ~~~a~~~l~~l~~---------------------~~~~~~~~~~-~~~~~~l~~~l~~~-----~~~~~~~~a~~~l~~l  269 (629)
T 4R0Z_A          217 IYTVVRCIRSLSV---------------------CPSNKPALIS-LGCLPALYVELCTA-----KDERSQTAILVAMRNL  269 (629)
T ss_dssp             HHHHHHHHHHHTT---------------------STTHHHHHHH-TTHHHHHHHHHHHC-----CCHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhc---------------------CcchHHHHHH-CChHHHHHHHHHhC-----CCHHHHHHHHHHHHHH
Confidence            3333333322110                     0001111111 12222222111110     1122334445555555


Q NP_000290.2     483 SYRLDAE------VPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLM  556 (747)
Q Consensus       483 ~~~~~~~------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL  556 (747)
                      +..-+..      ++.-...+..  .+.........++.+               ....+......+.+.++++.|+.++
T Consensus       270 ~~~~~~~~~~~~~i~~l~~~l~~--~~~~~~~~a~~~l~~---------------l~~~~~~~~~~~~~~~~~~~l~~~l  332 (629)
T 4R0Z_A          270 SDSATNEENLTQLIIKLLEIIRV--ANDGMTACACGTLSN---------------LTCNNTRNKQTVCSHGGIDALVTAI  332 (629)
T ss_dssp             GGGCCTTSCCHHHHHHHHHHTTT--CCHHHHHHHHHHHHH---------------HHTTCHHHHHHHHHTTHHHHHHHHH
T ss_pred             cCCcchHHHHHHHHHHHHHHHhc--CCHHHHHHHHHHHHH---------------HHcCCHHHHHHHHHCCHHHHHHHHH
Confidence            4322110      0000000000  000000011111111               1111112233346778888888888


Q NP_000290.2     557 GK-SKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMG-  633 (747)
Q Consensus       557 ~s-s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~-  633 (747)
                      .. ..+..++..++.+|.+++..... ... ....+...++++.|+.++.+.++.++..++.+|.+++..... ..+.. 
T Consensus       333 ~~~~~~~~~~~~a~~~l~~l~~~~~~-~~~-~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~  410 (629)
T 4R0Z_A          333 RRLPEVEEVTEPALCALRHCTARHSL-AEE-AQSELRFCQAFPVILDQLETLRTPVIKAALGVIRNSALLQTNLIELTQE  410 (629)
T ss_dssp             HHCTTCHHHHHHHHHHHHHHTSSSTT-HHH-HHHHHHHTTCHHHHHHHHTTCCHHHHHHHHHHHHHHTTSTTHHHHHHHC
T ss_pred             HhCCCcHHHHHHHHHHHHHhcccCCC-cHH-HHHHHhhcChHHHHHHHHhcCCHHHHHHHHHHHHHHcccchhHHHHHhc
Confidence            62 13446888999999999432110 000 123334567788899999888888999999999999876322 22211 


Q NP_000290.2     634 -----NQVFPEVTRLLTSHTG----------NTSNSEDILSSACYTVRNLMASQPQLAKQYFSS----------SMLNNI  688 (747)
Q Consensus       634 -----~giI~~Ll~LL~s~s~----------~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~----------giL~~L  688 (747)
                           .++++.++.++.....          ....+..++..++.+|.+++.. +.....+.+.          ++++.|
T Consensus       411 ~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~L~~l~~~-~~~~~~~~~~~~~~~~~~~~~~~~~l  489 (629)
T 4R0Z_A          411 QTANGHTAVSLTMDILRRAITAIEENPDIAVDGVPMWGVIEGAVSALHQLANH-PAVAAACCDDIGQVGNPECPPFLDLL  489 (629)
T ss_dssp             CCTTCCCHHHHHHHHHHHHHHHHHHCTTCEETTEEHHHHHHHHHHHHHHHTTS-HHHHHHHHHCCCCTTCTTSCCHHHHH
T ss_pred             cccCCccHHHHHHHHHHHHHHhcccCCCcccCCeeHHHHHHHHHHHHHHHhCC-HHHHHHHhhccccCCCCCCCcHHHHH
Confidence                 3455566666532000          0002345667788888888764 4444444443          567777


Q NP_000290.2     689 INLCR------SSASPKAAEAARLLLSDMWSSKELQGVLRQQGF  726 (747)
Q Consensus       689 l~LL~------s~~d~eVr~aAL~aLsnL~~~~~~~~~~~~~~~  726 (747)
                      ..++.      +. ++.++..++.+|.+++...+....+...|.
T Consensus       490 ~~~l~~~~~~~~~-~~~v~~~a~~~L~~l~~~~~~~~~l~~~~~  532 (629)
T 4R0Z_A          490 HRLLAHPRLGSMD-DEVLEREILGLLYQLSKRPDGARAVESTGV  532 (629)
T ss_dssp             HHHHTCHHHHTCS-CSHHHHHHHHHHHHHTSSHHHHHHHHTTTC
T ss_pred             HHHhcCcccCCCc-hHHHHHHHHHHHHHHhcCCChHhHHhhccH
Confidence            77776      44 778899999999999977766555554444


No 59
>1XM9_A plakophilin 1  Plakophilin-1; armadillo repeat, CELL ADHESION; 2.8A {Homo sapiens} SCOP: a.118.1.24
Probab=97.84  E-value=6.1e-09  Score=106.37  Aligned_cols=350  Identities=19%  Similarity=0.201  Sum_probs=191.7  Template_Neff=12.600

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .+++.+..++.+.++.++..++.++.+++.........+...++++.++.++. ..+..++..++.+|.+++... ....
T Consensus        44 ~~i~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~-~~~~  122 (457)
T 1XM9_A           44 GGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKE  122 (457)
T ss_dssp             THHHHHHHHTTSSCHHHHHHHHHHHHHHHSSCHHHHHHHHHTTCHHHHHHHHTTCCCHHHHHHHHHHHHHHHTSS-STHH
T ss_pred             CHHHHHHHHhcCCCHHHHHHHHHHHHHHhhCCHHHHHHHHhcChHHHHHHHhhhCCCHHHHHHHHHHHHHHhCCH-HHHH
Confidence            34566677777777888999999999988654443444445567778888876 556778888999999887632 2222


Q NP_000290.2     324 ETRRQNGIREAVSLL----------------RRTGNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVIIPFSG  385 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL----------------~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~~~~~~  385 (747)
                      .+. .++++.+..++                . ..++.++..++.++.+++........+..  ++++.|+.++......
T Consensus       123 ~~~-~~~~~~l~~~l~~~~~~~~~~~~~~~~~-~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~  200 (457)
T 1XM9_A          123 ELI-ADALPVLADRVIIPFSGWCDGNSNMSRE-VVDPEVFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAA  200 (457)
T ss_dssp             HHH-HHHHHHCCCCCCHHHHTCC----------CCCHHHHHHHHHHHHHHTTSHHHHHHHTTSTTHHHHHHHHHHHHHHH
T ss_pred             HHH-cchHHHHHHHhccccCCCCCCCCCcccc-cCCHHHHHHHHHHHHHHccChHHHHHHHhcccHHHHHHHHHHHhhhc
Confidence            222 45677777776                3 44667888899999999876544444443  5677777777642211


Q NP_000290.2     386 WCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLA-------LVPQR-ATSSRVNLSSAD-------------------  438 (747)
Q Consensus       386 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-------~~~~~-~~~~~~~~~~~~-------------------  438 (747)
                                ...++++...+..+|..-....+...       ..+.+ ...+.......+                   
T Consensus       201 ----------~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  270 (457)
T 1XM9_A          201 ----------SRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEE  270 (457)
T ss_dssp             ----------TCTTCTTHHHHHHHHHHHTTTHHHHSCCHHHHHHHTC----------------------------CCCCC
T ss_pred             ----------CcCCHHHHHHHHHHHHHHhcccccCCCcchhhhhhcccccccccccccccCcccchhccccccCCCCccc
Confidence                      11234444455544433211000000       00000 000000000000                   


Q NP_000290.2     439 ---AGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFS  515 (747)
Q Consensus       439 ---~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  515 (747)
                         .+++.+.. .+.+..|...+...     -+....+.+...|.|+...-                             
T Consensus       271 ~~~~~~~~~~~-~~~~~~l~~~l~~~-----~~~~~~~~a~~~L~~l~~~~-----------------------------  315 (457)
T 1XM9_A          271 TNPKGSGWLYH-SDAIRTYLNLMGKS-----KKDATLEACAGALQNLTASK-----------------------------  315 (457)
T ss_dssp             SSCCGGGGGGS-HHHHHHHHHHHHHC-----CCHHHHHHHHHHHHHHTTCS-----------------------------
T ss_pred             CCCchhHHhhc-hhHHHHHHHHhccC-----CCHHHHHHHHHHHHHHHhcc-----------------------------
Confidence               00000000 01111111111000     00000011111111111000                             


Q NP_000290.2     516 NKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEK  595 (747)
Q Consensus       516 ~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~g  595 (747)
                                     +.... ......+.+.++++.|+.++. +.++.++..++.+|.+++....      ....+ ..+
T Consensus       316 ---------------~~~~~-~~~~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~------~~~~~-~~~  371 (457)
T 1XM9_A          316 ---------------GLMSS-GMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLSNMSRHPL------LHRVM-GNQ  371 (457)
T ss_dssp             ---------------SSHHH-HHHHCCCCCSCCHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSGG------GHHHH-HHH
T ss_pred             ---------------ccccC-CcchhhhhhcchHHHHHHHHh-cCCHHHHHHHHHHHHHHhcCHH------HHHHH-Hcc
Confidence                           00000 001123456778899999998 4677888999999999986432      12232 345


Q NP_000290.2     596 GLPQIARLLQSG------NSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRN  667 (747)
Q Consensus       596 iI~~Ll~LL~s~------d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsn  667 (747)
                      +++.|+.++...      ++.++..++.+|.+|+.. +.. ..+...++++.|..++...     .++.++..++.+|.+
T Consensus       372 ~~~~l~~~l~~~~~~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~ll~~~-----~~~~v~~~a~~~L~~  446 (457)
T 1XM9_A          372 VFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSS-----ASPKAAEAARLLLSD  446 (457)
T ss_dssp             THHHHHHTTTSCCSCSTTHHHHHHHHHHHHHHHHTTCTHHHHHHCCHHHHHHHHHHHHCT-----TCHHHHHHHHHHHHT
T ss_pred             cHHHHHHHHhcCCCCCCCCHHHHHHHHHHHHHHHhcCHHHHHHHHhccHHHHHHHHHhCC-----CCHHHHHHHHHHHHH
Confidence            788888888765      678899999999999854 333 3445567788888887652     267888999999999


Q NP_000290.2     668 LMAS  671 (747)
Q Consensus       668 La~~  671 (747)
                      |+..
T Consensus       447 l~~~  450 (457)
T 1XM9_A          447 MWSS  450 (457)
T ss_dssp             TSSS
T ss_pred             Hhhc
Confidence            8864


No 60
>4I2Z_A Protein UNC-45, Heat shock protein; chaperone, myosin folding, protein filaments; 2.9A {Caenorhabditis elegans}
Probab=97.84  E-value=7.3e-09  Score=122.51  Aligned_cols=69  Identities=14%  Similarity=0.132  Sum_probs=41.5  Template_Neff=8.600

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVF  316 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~  316 (747)
                      ++.|+.++...+..++..+..++..+... ......+...+.++.|+.++.+.++..+..++.+|..++.
T Consensus       648 ~~~Lv~ll~~~s~~~r~~~~~~l~~l~~~-~~~R~~iv~~G~v~~Ll~ll~~~~~~~~~~Aa~ALa~l~~  716 (961)
T 4I2Z_A          648 VPACVAVSKTESKNALELIARSLLAFAEY-EDLRGRIIAEGGTVLCLRLTKEASGEGKIKAGHAIAKLGA  716 (961)
T ss_dssp             HHHHHHTCCCSCSHHHHHHHHHHHTTSCS-STTHHHHTTTTHHHHHHHHHHHSCTHHHHHHHHHHHHHSS
T ss_pred             HHHHHHHhcCCCHHHHHHHHHHHHHHhCC-HHHHHHHHHCchHHHHHHHHhcCChHHHHHHHHHHHHHHc
Confidence            44555555555566677777777777643 3344445555666777777665555566666666665543


No 61
>6SWY_5 Vacuolar import and degradation protein; Suppressed, Suppreseed, LIGASE; 3.2A { Saccharomyces cerevisiae YJM1133}
Probab=97.83  E-value=7.4e-09  Score=121.91  Aligned_cols=402  Identities=11%  Similarity=0.070  Sum_probs=223.3  Template_Neff=8.700

Q NP_000290.2     240 IECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLRSPN-QNVQQAAAGALRNLVFR  317 (747)
Q Consensus       240 ~~~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~s~d-~eVr~~AL~aLs~La~~  317 (747)
                      +...+.++..+..++...+..++..++.+|..++..... ....+...++++.++.++...+ +. +..++.+|..++..
T Consensus       281 l~~~~~~~~~L~~Ll~s~~~~lr~~Al~~L~~L~~~~~~~~~~~~~~~g~l~~Li~lL~~~~~~~-~~~al~~L~~L~~~  359 (921)
T 6SWY_5          281 LRNDATFKMFVLGLLKSNDVNIRCVALKFLLQPYFTEDKKWEDTRTLEKILPYLVKSFNYDPLPW-WFDPFDMLDSLIVL  359 (921)
T ss_dssp             STTCSHHHHHHHHHTTCSSHHHHHHHHHHHHHHHHHSSSTTSCHHHHHHHHHHHHHTTSCSSCCT-TCCHHHHHHHHHHH
T ss_pred             hhcccchHHHHHHHhcCCCHHHHHHHHHHHHHHHhCCCCchhhHHHHccHHHHHHHHcCCCCCch-hchHHHHHHHHHHH
Confidence            334455566666777777788899999999998865332 1233344567888888887654 44 77888888888762


Q NP_000290.2     318 S-------TTNKLETRRQNGIRE-AVSLLRRTG--------NAEIQKQLTGLLWNLSSTDEL-KEELIA--DALPVLADR  378 (747)
Q Consensus       318 ~-------~~~~~~ll~~~IL~~-Ll~lL~ss~--------d~eVr~~AL~aLsnLas~~~~-~~~Lve--giLe~Lv~L  378 (747)
                      .       ......+...+.+.. +..++. ..        +..++..++.++..++..... ...+..  ++++.|+.+
T Consensus       360 ~~~~~~~~~~~~~~l~~~g~i~~lL~~ll~-~~~~~~~~~~~~~v~~~al~~L~~L~~~~e~~r~~l~~~~~~l~~L~~l  438 (921)
T 6SWY_5          360 YNEITPMNNPVLTTLAHTNVIFCILSRFAQ-CLSLPQHNEATLKTTTKFIKICASFAASDEKYRLLLLNDTLLLNHLEYG  438 (921)
T ss_dssp             HHHHSTTCCHHHHHHHHTTHHHHHHHHHHH-HHTCSSCCHHHHHHHHHHHHHHHHHHTSCHHHHHHHHTTSSHHHHHHHH
T ss_pred             hcccCCCCCHHHHHHHHcChHHHHHHHHHH-hcCCccCCcCCHHHHHHHHHHHHHHhCCCHHHHHHHhccccHHHHHHHH
Confidence            1       111122223455565 555554 33        566778888999888875432 232333  567777777


Q NP_000290.2     379 VIIPF-------SGWC------DGNSNMS-REVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAG-RQT  443 (747)
Q Consensus       379 L~~~~-------~~~~------~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~  443 (747)
                      +....       +.|-      .+....+ ....|+++...+..+|+.                     ++..... ++.
T Consensus       439 L~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~d~~v~~~al~~L~~---------------------Ls~~~~~lr~~  497 (921)
T 6SWY_5          439 LESHITLIQDFISLKDEIKETTTESHSMCLPPIYDHDFVAAWLLLLKS---------------------FSRSVSALRTT  497 (921)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHTTTCTTCCCCCTTHHHHHHHHHHHHH---------------------HTTCHHCCCCC
T ss_pred             HHhhHHHHHHHHhccHHHHhcccccccCCCCCCCCHHHHHHHHHHHHH---------------------HhCCHHHHHHH
Confidence            76220       0000      0000000 011124444444444432                     1111111 111


Q NP_000290.2     444 MRNYSGLIDSLMAYVQNCVA-ASRC----------DDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTG  512 (747)
Q Consensus       444 ~~~~~~~~~~~~~~~~~~~~-~~~~----------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  512 (747)
                      +.. .|++..|...++.... ...|          +..-...+...|.|++..-                          
T Consensus       498 l~~-~g~i~~Ll~lL~~~~~~~~~~~~~~~~~~~~~~~v~~~al~aL~nL~~~~--------------------------  550 (921)
T 6SWY_5          498 LKR-NKIAQLLLQILSKTYTLTKECYFAGQDFMKPEIMIMGITLGSICNFVVEF--------------------------  550 (921)
T ss_dssp             SCC-HHHHHHHHHHHHHHHHHHHHCGGGCSTTTHHHHHHHHHHHHHHHHHTSSS--------------------------
T ss_pred             HHH-CChHHHHHHHHHhhccchHhhhcCCcccccccHHHHHHHHHHHHHHHccC--------------------------
Confidence            111 2444444444432200 0000          1111122222222222110                          


Q NP_000290.2     513 CFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKS----------------------KKDATLEACAG  570 (747)
Q Consensus       513 ~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss----------------------~d~eVr~~AL~  570 (747)
                                              ......+++.|+++.|+.++...                      .+..++..+++
T Consensus       551 ------------------------~~~~~~l~~~gii~~L~~lL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~al~  606 (921)
T 6SWY_5          551 ------------------------SNLQSFMLRNGIIDIIEKMLTDPLFNSKKAWDDNEDERRIALQGIPVHEVKANSLW  606 (921)
T ss_dssp             ------------------------CTTHHHHHHTTHHHHHHHHHTSTTTCTTSCCCSSCHHHHHHSTTSCCSHHHHHHHH
T ss_pred             ------------------------chHHHHHHHCCHHHHHHHHhcChhhccccccCCCccHHHHHhcCCCCHHHHHHHHH
Confidence                                    01112234556677777766521                      45677889999


Q NP_000290.2     571 ALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL-----------L-HRVMG-----  633 (747)
Q Consensus       571 aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e-----------~-~~ll~-----  633 (747)
                      +|.+++.....   . ....+...++++.|+.++.+.++.++..++++|.+++....           . ...+.     
T Consensus       607 aL~nL~~~~~~---~-~~~~l~~~~~l~~Ll~lL~~~~~~v~~~a~~~L~nL~~~~~~~~~~ll~~~~~~~~l~~~~~~~  682 (921)
T 6SWY_5          607 VLRHLMYNCQN---E-EKFQLLAKIPMNLILDFINDPCWAVQAQCFQLLRNLTCNSRKIVNILLEKFKDVEYKIDPQTGN  682 (921)
T ss_dssp             HHHHHTTTCCH---H-HHHHHHHHSCHHHHHTTTTCSSHHHHHHHHHHHHHHHTTCSHHHHHHHHTC-------------
T ss_pred             HHHHHHcCCCH---H-HHHHHHhcCCHHHHHHHHcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHhhcccceeeCcCCCC
Confidence            99999875331   0 12344566888999999988888999999999999987632           1 12222     


Q NP_000290.2     634 ------NQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSS-SMLNNIINLCR---------SSAS  697 (747)
Q Consensus       634 ------~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~-giL~~Ll~LL~---------s~~d  697 (747)
                            .++++.|+..+.........+..++..++++|.+++...+.....+++. ++++.|..++.         .. +
T Consensus       683 ~~~~~~~~ll~~L~~~L~~~~~~~~~~~~v~~~al~~L~nLa~~~~~~~~~ii~~~~il~~L~~lL~~~~~~~~~~~~-~  761 (921)
T 6SWY_5          683 KISIGSTYLFEFLAKKMRLLNPLDTQQKKAMEGILYIIVNLAAVNENKKQLVIEQDEILNIMSEILVETTTDSSSYGN-D  761 (921)
T ss_dssp             ------CCHHHHHHHHHHHSCTTSHHHHHHHHHHHHHHHHHHTSCHHHHHHHHHCHHHHHHHHHHHTCCSSCCSSGGG-C
T ss_pred             ccccccccHHHHHHHHHhccCCCchhcHHHHHHHHHHHHHHHcCCHHHHHHHHhCchHHHHHHHHHHhcCCCccccCC-C
Confidence                  3567777777765200000156788999999999997654544444544 67888888887         44 6


Q NP_000290.2     698 PKAAEAARLLLSDMWSSKELQGV  720 (747)
Q Consensus       698 ~eVr~aAL~aLsnL~~~~~~~~~  720 (747)
                      +.++..++++|.+|+...+.+..
T Consensus       762 ~~v~~~al~aL~nL~~~~~~~~~  784 (921)
T 6SWY_5          762 SNLKLACLWVLNNLLWNSSVSHY  784 (921)
T ss_dssp             HHHHHHHHHHHHHHHCC------
T ss_pred             HHHHHHHHHHHHHHHcCCCcccc
Confidence            78999999999999987655433


No 62
>5IZ8_A Adenomatous polyposis coli protein, ACE-ALA-GLY-GLU-ALA-LEU-ALA-ASP-NH2; APC, ASEF, Colon CANCER, Drug; HET: PGE; 3.06A {Homo sapiens}
Probab=97.83  E-value=6.6e-09  Score=103.80  Aligned_cols=297  Identities=19%  Similarity=0.226  Sum_probs=179.9  Template_Neff=12.000

Q NP_000290.2     236 CSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP-----------NQNVQ  304 (747)
Q Consensus       236 ~~~~~~~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~-----------d~eVr  304 (747)
                      |.+-++-.+.........+.+.++.++..++.+|.++... ......+...++++.+..++...           +..++
T Consensus        23 ~~~~~~~~~~~~~~~~~~l~~~~~~~~~~a~~~L~~l~~~-~~~~~~~~~~~~~~~L~~~l~~~~~~~~~~~~~~~~~~~  101 (354)
T 5IZ8_A           23 CWEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFD-EEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSITLR  101 (354)
T ss_dssp             HHHHHHHSCSSCCCCSSCCCCGGGGTHHHHHHHHHHHHTS-HHHHHHHHHTTHHHHHHHHHHHHHHHHCSCCCHHHHHHH
T ss_pred             HHHHHHhcCCCCCCCCCCCCCCchHhHHHHHHHHHHccCC-HHHHHHHHHcCHHHHHHHHHHhhHHHhCCCCCCCCHHHH
Confidence            4443343344444444555667778888899999988765 33333344456777777777643           67788


Q NP_000290.2     305 QAAAGALRNLVFRSTTNKLETRR-QNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST--DELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       305 ~~AL~aLs~La~~~~~~~~~ll~-~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~--~~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ..++.++.+++.........+.. .++++.+..++. ..++.++..++.++.+++..  ......+.. ++++.|+.++.
T Consensus       102 ~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  180 (354)
T 5IZ8_A          102 RYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLK-SESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECAL  180 (354)
T ss_dssp             HHHHHHHHHHHTTCHHHHHHHHHCHHHHHHHHHGGG-SSCHHHHHHHHHHHHHHHTTCCHHHHHHHHHTTHHHHHHHHHH
T ss_pred             HHHHHHHHHHhcCCHHHHHHHHccchHHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCCChhHHHHHHHCCHHHHHHHHHH
Confidence            88999999987644333333333 467777888886 55678888999999999874  222333444 77777877776


Q NP_000290.2     381 IPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSA-DAGRQTMRNYSGLIDSLMAYVQ  459 (747)
Q Consensus       381 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~  459 (747)
                      ..               .++++...+..+|..                     +... +..++.+..-.|.++.|...+.
T Consensus       181 ~~---------------~~~~~~~~a~~~L~~---------------------l~~~~~~~~~~~~~~~~~~~~l~~~l~  224 (354)
T 5IZ8_A          181 EV---------------KKESTLKSVLSALWN---------------------LSAHCTENKADICAVDGALAFLVGTLT  224 (354)
T ss_dssp             HC---------------CSHHHHHHHHHHHHH---------------------HHTSCHHHHHHHHTSTTHHHHHHHHTT
T ss_pred             hc---------------CCHHHHHHHHHHHHH---------------------HHcCChHhHHHHHhhccHHHHHHHHHh
Confidence            42               133443333333322                     1111 1122222221345555555444


Q NP_000290.2     460 NCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKG  539 (747)
Q Consensus       460 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~  539 (747)
                      ...  ...+..-.+.+..+|.+++..+.                                               .+...
T Consensus       225 ~~~--~~~~~~~~~~~~~~L~~l~~~~~-----------------------------------------------~~~~~  255 (354)
T 5IZ8_A          225 YRS--QTNTLAIIESGGGILRNVSSLIA-----------------------------------------------TNEDH  255 (354)
T ss_dssp             CCC--TTSCCHHHHHHHHHHHHHHHHHH-----------------------------------------------TCHHH
T ss_pred             hcC--CCCcHHHHHHHHHHHHHHHHHhc-----------------------------------------------CCHHH
Confidence            210  01113334555555666541100                                               01112


Q NP_000290.2     540 SGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLL  619 (747)
Q Consensus       540 ~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aL  619 (747)
                      ...+.+.++++.|+.++. ..++.++..++.+|.+++...+.     ....+.+.++++.|+.++.+.++.++..++.+|
T Consensus       256 ~~~l~~~~~~~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L  329 (354)
T 5IZ8_A          256 RQILRENNCLQTLLQHLK-SHSLTIVSNACGTLWNLSARNPK-----DQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL  329 (354)
T ss_dssp             HHHHHTTTHHHHHHHTTT-CSCHHHHHHHHHHHHHHSSSCHH-----HHHHHHTTTHHHHHHHHSSCSSHHHHHHHHHHH
T ss_pred             HHHHHHCCHHHHHHHHhh-cCCHHHHHHHHHHHHHHHccCHH-----HHHHHHhCCHHHHHHHHHhccCHHHHHHHHHHH
Confidence            223356678888888887 46777888999999999874332     233445678899999999888888999999999


Q NP_000290.2     620 SNMSRH  625 (747)
Q Consensus       620 snLa~~  625 (747)
                      .+++..
T Consensus       330 ~~l~~~  335 (354)
T 5IZ8_A          330 RNLMAN  335 (354)
T ss_dssp             HHHHTT
T ss_pred             HHHHcc
Confidence            999876


No 63
>3IFQ_A plakoglobin, E-cadherin; armadillo repeat, Cardiomyopathy, Cell adhesion; HET: SO4; 2.8A {Homo sapiens}
Probab=97.83  E-value=6.4e-09  Score=107.67  Aligned_cols=374  Identities=16%  Similarity=0.150  Sum_probs=218.5  Template_Neff=13.100

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      ..+++.+...+.+.++.++..++.++..+..............++++.+...+. ..++.++..++.++..+..... ..
T Consensus        18 ~~~~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~-~~   96 (553)
T 3IFQ_A           18 TRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHRE-GL   96 (553)
T ss_dssp             HHTHHHHHHHHTCSCHHHHHHHHHHHHHHTTSHHHHHHHHTCHHHHHHHHHHHTTCCCHHHHHHHHHHHHHHTTSHH-HH
T ss_pred             cCcHHHHHHHhcCCCHHHHHHHHHHHHHHhCCHHHHHHHhcCchHHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCHH-HH
Confidence            345666777777777888888999998887653221111112356666777666 4556778888888888775432 22


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDP  400 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~  400 (747)
                      ..+...+.++.+...+. +.++.++..++.++..++..... ...+.. ++++.|..++...                ++
T Consensus        97 ~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~  159 (553)
T 3IFQ_A           97 LAIFKSGGIPALVRMLS-SPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKN----------------NP  159 (553)
T ss_dssp             HHHHHTTHHHHHHHGGG-CCCHHHHHHHHHHHHHHHHHCTTHHHHHHHTTGGGGTGGGGGSS----------------CH
T ss_pred             HHHHHcCcHHHHHHHcc-CCCHHHHHHHHHHHHHHhcCChHHHHHHHhcCHHHHHHHHHhcC----------------CH
Confidence            22333456777777776 55677888888888888764332 222222 6666676666531                33


Q NP_000290.2     401 EVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH  480 (747)
Q Consensus       401 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  480 (747)
                      ++...+..+|..-...      .+              ..+..+ --.++++.|...+...     .+......++..|.
T Consensus       160 ~~~~~a~~~l~~l~~~------~~--------------~~~~~~-~~~~~~~~l~~~l~~~-----~~~~~~~~a~~~l~  213 (553)
T 3IFQ_A          160 KFLAITTDCLQLLAYG------NQ--------------ESKLII-LANGGPQALVQIMRNY-----SYEKLLWTTSRVLK  213 (553)
T ss_dssp             HHHHHHHHHHHHHHTT------CH--------------HHHHHH-HHTTHHHHHHHHHHHC-----CCHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHcC------CH--------------HHHHHH-HHCCHHHHHHHHHhcC-----CcHHHHHHHHHHHH
Confidence            4444444433321100      00              000000 0113344443333210     01111222223333


Q NP_000290.2     481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSK  560 (747)
Q Consensus       481 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~  560 (747)
                      +++..-                                                   .....+.+.++++.++.++. +.
T Consensus       214 ~l~~~~---------------------------------------------------~~~~~~~~~~~~~~l~~~l~-~~  241 (553)
T 3IFQ_A          214 VLSVCP---------------------------------------------------SNKPAIVEAGGMQALGKHLT-SN  241 (553)
T ss_dssp             HHTTST---------------------------------------------------THHHHHHHTTHHHHHHGGGG-SS
T ss_pred             HHhCCc---------------------------------------------------chHHHHHHCchHHHHHHHHh-cC
Confidence            322100                                                   00112234567888888887 46


Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVFP  638 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI~  638 (747)
                      ++.++..++.+|.+++.....      ...  ..++++.+..++.+.++.++..++.+|.+++... .. ..+...++++
T Consensus       242 ~~~~~~~a~~~l~~l~~~~~~------~~~--~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~  313 (553)
T 3IFQ_A          242 SPRLVQNCLWTLRNLSDVATK------QEG--LESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVE  313 (553)
T ss_dssp             CHHHHHHHHHHHHHHHTTCTT------CSC--CHHHHHHHHTTTTCCCHHHHHHHHHHHHHHTTTCHHHHHHHTTTTHHH
T ss_pred             CHHHHHHHHHHHHHhCChhHH------HHH--HHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHccHHH
Confidence            778888999999999865321      111  2467888888888888889999999999998763 22 2334455777


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ---LAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e---~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      .+...+...    ..++.++..++.+|.+++...+.   ....+...+.++.+..++.+..++.++..++.+|.+++...
T Consensus       314 ~l~~~l~~~----~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~  389 (553)
T 3IFQ_A          314 ALIHAILRA----GDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCP  389 (553)
T ss_dssp             HHHHHHHHH----TTCHHHHHHHHHHHHHHTSSSTTHHHHHHHHHTTTHHHHHHHGGGCTTCHHHHHHHHHHHHHHTTSG
T ss_pred             HHHHHHHHc----CCChHhHHHHHHHHHHHhcCCChHHHHHHHHHHcchHHHHHHHHcCCCChHHHHHHHHHHHHHhcCc
Confidence            777766531    02567888999999999875332   11223344567888888876523788899999999998876


Q NP_000290.2     716 ELQGVLRQQG  725 (747)
Q Consensus       716 ~~~~~~~~~~  725 (747)
                      +....+...|
T Consensus       390 ~~~~~~~~~~  399 (553)
T 3IFQ_A          390 ANHAPLQEAA  399 (553)
T ss_dssp             GGHHHHHHTT
T ss_pred             ccHHHHHHcc
Confidence            6554444333


No 64
>4I2W_A Protein UNC-45, Heat shock 70; chaperone, myosin folding, protein filaments; 3.6A {Caenorhabditis elegans}
Probab=97.83  E-value=7.9e-09  Score=122.23  Aligned_cols=70  Identities=14%  Similarity=0.133  Sum_probs=42.2  Template_Neff=8.600

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVF  316 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~  316 (747)
                      +++.|+.++...+..++..+..++..+... ......+...+.++.|+.++.+.++..+..++.+|..++.
T Consensus       647 ~~~~Lv~ll~~~s~~~r~~~~~~l~~l~~~-~~~R~~ivq~g~~~~Ll~ll~~~~~~~~~~Aa~ALa~l~~  716 (961)
T 4I2W_A          647 AVPACVAVSKTESKNALELIARSLLAFAEY-EDLRGRIIAEGGTVLCLRLTKEASGEGKIKAGHAIAKLGA  716 (961)
T ss_dssp             SSHHHHHTTCCCCSHHHHHHHHHHHTTSSS-STTTTTTTTSSHHHHHHHHHHHSTTHHHHHHHHHHHTTSS
T ss_pred             CHHHHHHHhcCCCHHHHHHHHHHHHHHhCC-HHHHHHHHHCchHHHHHHHHhcCChHHHHHHHHHHHHHHc
Confidence            344555555555566677777777777643 3344445555666777776665555566666666666653


No 65
>4R10_A Protein humpback-2, Cadherin-related hmr-1; armadillo repeat, cell adhesion, phosphorylation; HET: SEP; 2.3A {Caenorhabditis elegans}
Probab=97.79  E-value=8.7e-09  Score=108.23  Aligned_cols=398  Identities=14%  Similarity=0.146  Sum_probs=205.5  Template_Neff=12.700

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++.........+...++++.+...+...++.++..++.++..++.........+
T Consensus       115 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  194 (572)
T 4R10_A          115 GLAEIIRMLYDSLESVVHYAVTTLRNLLMHVSDSRAQARALNAVEALTPHLHKTNPKLLAQVADGLYFLLIDDAPSKITF  194 (572)
T ss_dssp             THHHHHHGGGCSCHHHHHHHHHHHHHHHHHCTHHHHHHHHTTHHHHHGGGGGCCCHHHHHHHHHHHHHHHTTCHHHHHHH
T ss_pred             cHHHHHHHHhCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHHhcCCHHHHHHHHHHHHHHHCCChHHHHHH
Confidence            34555666666677888889999998866443333334444677778888877778888899999988875443333333


Q NP_000290.2     326 RRQNGIREAVSLLRR-TGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       326 l~~~IL~~Ll~lL~s-s~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ...+++..+...+.. ..+..++..++.++..++........+.. ++++.++..+...               .++++.
T Consensus       195 ~~~~~~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~~~~~~  259 (572)
T 4R10_A          195 LSLLGPQILVSILREYSDHRKLIYTVVRCIRSLSVCPSNKPALISLGCLPALYVELCTA---------------KDERSQ  259 (572)
T ss_dssp             HHTTHHHHHHHHHHHCTTCHHHHHHHHHHHHHHTTSTTHHHHHHHTTHHHHHHHHHTTC---------------CSHHHH
T ss_pred             HhccHHHHHHHHHHHCCCCHHHHHHHHHHHHHHhcCcchHHHHHhCCcHHHHHHHHhcC---------------CCHHHH
Confidence            344566667766641 23456778888888888765443333333 5555554433321               123333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-..                     ....++.+   .+++..+...++.      -+..-...+...|.++.
T Consensus       260 ~~a~~~l~~l~~---------------------~~~~~~~~---~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  309 (572)
T 4R10_A          260 TAILVAMRNLSD---------------------SATNEENL---TQLIIKLLEIIRV------ANDGMTACACGTLSNLT  309 (572)
T ss_dssp             HHHHHHHHHHGG---------------------GCTTCSCC---HHHHHHHHHHHHH------CCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHcC---------------------ChHHHHHH---HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHH
Confidence            333333322110                     00011111   1123333322211      12222333444444444


Q NP_000290.2     484 YRLDAEVP---------TRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLN  554 (747)
Q Consensus       484 ~~~~~~~~---------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~  554 (747)
                      ..-+....         .-...+.....+.........+..+-..    .        ...+......+...++++.++.
T Consensus       310 ~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~----~--------~~~~~~~~~~~~~~~~~~~l~~  377 (572)
T 4R10_A          310 CNNTRNKQTVCSHGGIDALVTAIRRLPEVEEVTEPALCALRHCTA----R--------HSLAEEAQSELRFCQAFPVILD  377 (572)
T ss_dssp             SSCHHHHHHHHHTTHHHHHHHHHHHSTTCHHHHHHHHHHHHHHTS----S--------STTHHHHHHHHHHTTHHHHHHH
T ss_pred             cCCHHHHHHHHHCcHHHHHHHHHHhCCCcHHHHHHHHHHHHHhhc----c--------CCCcHHHHHHHhhCChHHHHHH
Confidence            32111000         0000000000000000000000000000    0        0000111122245567788888


Q NP_000290.2     555 LMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLK------EKGLPQIARLLQS----------------GNSDVV  612 (747)
Q Consensus       555 LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie------~giI~~Ll~LL~s----------------~d~eVr  612 (747)
                      ++. +.+..++..++.+|.+++.....      ...+.+      .++++.+..++..                .++.++
T Consensus       378 ~l~-~~~~~v~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~  450 (572)
T 4R10_A          378 QLE-TLRTPVIKAALGVIRNSALLQTN------LIELTQEQTANGHTAVSLTMDILRRAITAIEENPDIAVDGVPMWGVI  450 (572)
T ss_dssp             HHT-TCCHHHHHHHHHHHHHHHTSHHH------HHHHHHCCCTTCCCHHHHHHHHHHHHHHHHHHCTTCEETTEEHHHHH
T ss_pred             HHh-cCCHHHHHHHHHHHHHHhccchh------HHHHHHHhhhCCCCcHHHHHHHHHHHHHhcccCcchhccCccHHHHH
Confidence            887 36667777888888888764221      111122      2344555555432                234566


Q NP_000290.2     613 RSGASLLSNMSRHPLLH-RVMGN----------QVFPEVTRLL------TSHTGNTSNSEDILSSACYTVRNLMASQPQL  675 (747)
Q Consensus       613 ~~AL~aLsnLa~~~e~~-~ll~~----------giI~~Ll~LL------~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~  675 (747)
                      ..++.+|.+++...... .+...          ++++.+..++      ..      .++.++..++.+|.+++.. +..
T Consensus       451 ~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~------~~~~v~~~a~~~l~~l~~~-~~~  523 (572)
T 4R10_A          451 EGAVSALHQLANHPAVAAACCDDIGQVGNPECPPFLDLLHRLLAHPRLGSM------DDEVLEREILGLLYQLSKR-PDG  523 (572)
T ss_dssp             HHHHHHHHHHTTSHHHHHHHHHCCCCTTCTTSCCHHHHHHHHHHSHHHHSC------SCSHHHHHHHHHHHHHTSS-HHH
T ss_pred             HHHHHHHHHHhCCHHHHHHHhccccCCCCCCCccHHHHHHHHHhCcccCCC------ChHHHHHHHHHHHHHHhcC-Cch
Confidence            77788888877653221 11111          4666666666      33      3677888888888888865 344


Q NP_000290.2     676 AKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       676 ~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ...+...++++.|..++.+. ++.++..++.+|.++....
T Consensus       524 ~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~L~~l~~~~  562 (572)
T 4R10_A          524 ARAVESTGVSALLMESRGSQ-YKSVVTYANGVLSNLKRGD  562 (572)
T ss_dssp             HHHHHTTTTHHHHHHHTTCS-CHHHHHHHHHHHHHHHHHH
T ss_pred             hhHHHHcChhhHHhHhhCCC-CchHHHHHHHHHHHhhcCC
Confidence            44455566778888888766 7788888888888887654


No 66
>5T94_B Guanine nucleotide exchange factor SRM1; Nuclear Import, Importin alpha, RCC1; 2.631A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=97.78  E-value=9.3e-09  Score=108.50  Aligned_cols=159  Identities=19%  Similarity=0.225  Sum_probs=117.7  Template_Neff=12.200

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      ...++++.|+.++. ..++.++..++.+|.+++.....     ....+...++++.|..++.+.++.++..++.+|.+++
T Consensus       254 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~  327 (542)
T 5T94_B          254 VVSQALPTLAKLIY-SMDTETLVDACWAISYLSDGPQE-----AIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIV  327 (542)
T ss_dssp             HHGGGHHHHHHHTT-CCCHHHHHHHHHHHHHHSSSSHH-----HHHHHHHTTCHHHHHHTTSCSSHHHHHHHHHHHHHHT
T ss_pred             HHhcHHHHHHHHHh-cCCHHHHHHHHHHHHHHcCCCHH-----HHHHHHhCCHHHHHHHHhcCCCHHHHHHHHHHHHHHH
Confidence            34556777777777 46677888899999988865332     2333345668888888888888889999999999998


Q NP_000290.2     624 RHPL-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA  701 (747)
Q Consensus       624 ~~~e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr  701 (747)
                      .... . ......++++.|..++.+      .++.++..++++|.+++...+.....+...++++.|+.++.+. ++.++
T Consensus       328 ~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~  400 (542)
T 5T94_B          328 TGNDLQTQVVINAGVLPALRLLLSS------PKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVA-EYKTK  400 (542)
T ss_dssp             TSCHHHHHHHHHTTHHHHHHHHTTC------SSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHHHHHS-CHHHH
T ss_pred             cCCHHHHHHHHHCChHHHHHHHhhC------CCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCchHHHHHHHHcC-CHHHH
Confidence            7632 2 233445678888888866      3678889999999999876555555566666788888888766 77888


Q NP_000290.2     702 EAARLLLSDMWSSK  715 (747)
Q Consensus       702 ~aAL~aLsnL~~~~  715 (747)
                      ..++.+|.+++...
T Consensus       401 ~~a~~~l~~l~~~~  414 (542)
T 5T94_B          401 KEACWAISNASSGG  414 (542)
T ss_dssp             HHHHHHHHHHHGGG
T ss_pred             HHHHHHHHHHHcCC
Confidence            99999999888764


No 67
>6KBN_A Vacuolar protein 8, Autophagy-related protein; Armadillo repeats, complex, PROTEIN BINDING-PROTEIN; 3.2A {Saccharomyces cerevisiae}
Probab=97.78  E-value=9.2e-09  Score=107.80  Aligned_cols=358  Identities=22%  Similarity=0.258  Sum_probs=207.0  Template_Neff=12.700

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+.......    ....+++.+...+.+.++.++..++.++..++..... ...
T Consensus        32 ~~i~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~----~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~-~~~  106 (563)
T 6KBN_A           32 GPLKALTTLVYSDNLNLQRSAALAFAEITEKYVRQ----VSREVLEPILILLQSQDPQIQVAACAALGNLAVNNEN-KLL  106 (563)
T ss_dssp             CTHHHHHHHHTTCCHHHHHHHHHHHHHHHHHCCCC----CCHHHHHHHHHHHSSCCHHHHHHHHHHHHHHTTSHHH-HHH
T ss_pred             CHHHHHHHHhcCCCHHHHHHHHHHHHHHhhhhHHH----hccchHHHHHHHhcCCCHHHHHHHHHHHHHHHcCcch-HHH
Confidence            34566666676677788888888888876532211    2245666777777777777888888888887754322 222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ....+.++.+...+. ..++.++..++.++..++........+.. ++++.|..++...                ++++-
T Consensus       107 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~v~  169 (563)
T 6KBN_A          107 IVEMGGLEPLINQMM-GDNVEVQCNAVGCITNLATRDDNKHKIATSGALIPLTKLAKSK----------------HIRVQ  169 (563)
T ss_dssp             HHHHTCHHHHHHHHH-SSCHHHHHHHHHHHHHTTCSHHHHHHHHTTTTHHHHHHHTTCS----------------SHHHH
T ss_pred             HHHCCcHHHHHHHhh-CCCHHHHHHHHHHHHHHhCCCchHHHHHhcChHHHHHHHccCC----------------CHHHH
Confidence            233355666777665 45667788888888888765433222222 5566666655421                23333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-.                     .....+..+. ..++++.+...++.      -+..-...+...|.++.
T Consensus       170 ~~a~~~l~~l~---------------------~~~~~~~~~~-~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  221 (563)
T 6KBN_A          170 RNATGALLNMT---------------------HSEENRKELV-NAGAVPVLVSLLSS------TDPDVQYYCTTALSNIA  221 (563)
T ss_dssp             HHHHHHHHHTT---------------------SSHHHHHHHH-TTTCHHHHHHHTTC------SSHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHh---------------------CCHHHHHHHH-HCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHh
Confidence            33333322110                     0000111111 12344444444331      11222223333333332


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ...+                                                . .........++++.+..++. +.++.
T Consensus       222 ~~~~------------------------------------------------~-~~~~~~~~~~~~~~l~~~l~-~~~~~  251 (563)
T 6KBN_A          222 VDEA------------------------------------------------N-RKKLAQTEPRLVSKLVSLMD-SPSSR  251 (563)
T ss_dssp             TSHH------------------------------------------------H-HHHHHHHCSSHHHHHHHHTT-CSCHH
T ss_pred             CCHH------------------------------------------------H-HHHHHhhchhHHHHHHHHhc-CCCHH
Confidence            2000                                                0 00000012346777888887 46777


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTR  642 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~  642 (747)
                      ++..++.+|.+++.....      ...+...++++.+..++.+.++.++..++.+|.+++..... ......++++.+..
T Consensus       252 ~~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~  325 (563)
T 6KBN_A          252 VKCQATLALRNLASDTSY------QLEIVRAGGLPHLVKLIQSDSIPLVLASVACIRNISIHPLNEGLIVDAGFLKPLVR  325 (563)
T ss_dssp             HHHHHHHHHHHHTTSHHH------HHHHHHTTCHHHHHHHHTCSCHHHHHHHHHHHHHHHTSGGGHHHHHHTTCHHHHHT
T ss_pred             HHHHHHHHHHHHhCChhH------HHHHHHCCcHHHHHHHHhCCCHHHHHHHHHHHHHHhcCcchHHHHHHCCcHHHHHH
Confidence            888999999998875321      22334567888888888888888999999999999876433 23344567788888


Q NP_000290.2     643 LLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       643 LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++...     .++.++..++.+|.+++...+.....+...++++.+..++.+. ++.++..++.++..+...
T Consensus       326 ~l~~~-----~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~l~~l~~~  391 (563)
T 6KBN_A          326 LLDYK-----DSEEIQCHAVSTLRNLAASSEKNRKEFFESGAVEKCKELALDS-PVSVQSEISACFAILALA  391 (563)
T ss_dssp             TTTCT-----TCHHHHHHHHHHHHHHHHHCSTTHHHHHHTTHHHHHHHHHTSS-CHHHHHHHHHHHHHHTTC
T ss_pred             HhCCC-----CCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHhCC-CHHHHHHHHHHHHHHhcC
Confidence            87652     2478888999999999876444444455555677777776654 556666666666655543


No 68
>6KBN_C Vacuolar protein 8, Autophagy-related protein; Armadillo repeats, complex, PROTEIN BINDING-PROTEIN; 3.2A {Saccharomyces cerevisiae}
Probab=97.78  E-value=9.2e-09  Score=107.80  Aligned_cols=358  Identities=22%  Similarity=0.258  Sum_probs=206.7  Template_Neff=12.700

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+.......    ....+++.+...+.+.++.++..++.++..++..... ...
T Consensus        32 ~~i~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~----~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~-~~~  106 (563)
T 6KBN_C           32 GPLKALTTLVYSDNLNLQRSAALAFAEITEKYVRQ----VSREVLEPILILLQSQDPQIQVAACAALGNLAVNNEN-KLL  106 (563)
T ss_dssp             -CHHHHHHHHTTCCHHHHHHHHHHHHHHHHHCCCC----CCHHHHHHHHHHHCCSCHHHHHHHHHHHHHHTTSHHH-HHH
T ss_pred             CHHHHHHHHhcCCCHHHHHHHHHHHHHHhhhhHHH----hccchHHHHHHHhcCCCHHHHHHHHHHHHHHHcCcch-HHH
Confidence            34566666676677788888888888876532211    2245666777777777777888888888887754322 222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ....+.++.+...+. ..++.++..++.++..++........+.. ++++.|..++...                ++++-
T Consensus       107 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~v~  169 (563)
T 6KBN_C          107 IVEMGGLEPLINQMM-GDNVEVQCNAVGCITNLATRDDNKHKIATSGALIPLTKLAKSK----------------HIRVQ  169 (563)
T ss_dssp             HHHTSCSHHHHHHTT-SSCHHHHHHHHHHHHHTTCSHHHHHHHHGGGCHHHHHHHTTSS----------------SHHHH
T ss_pred             HHHCCcHHHHHHHhh-CCCHHHHHHHHHHHHHHhCCCchHHHHHhcChHHHHHHHccCC----------------CHHHH
Confidence            233355666777665 45667788888888888765433222222 5566666655421                23333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-.                     .....+..+. ..++++.+...++.      -+..-...+...|.++.
T Consensus       170 ~~a~~~l~~l~---------------------~~~~~~~~~~-~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  221 (563)
T 6KBN_C          170 RNATGALLNMT---------------------HSEENRKELV-NAGAVPVLVSLLSS------TDPDVQYYCTTALSNIA  221 (563)
T ss_dssp             HHHHHHHHHHT---------------------SSHHHHHHHH-TTTCHHHHHHHTTC------SSHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHh---------------------CCHHHHHHHH-HCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHh
Confidence            33333322110                     0000111111 12344444444331      11222223333333332


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ...+                                                . .........++++.+..++. +.++.
T Consensus       222 ~~~~------------------------------------------------~-~~~~~~~~~~~~~~l~~~l~-~~~~~  251 (563)
T 6KBN_C          222 VDEA------------------------------------------------N-RKKLAQTEPRLVSKLVSLMD-SPSSR  251 (563)
T ss_dssp             TSHH------------------------------------------------H-HHHHHHSSTTHHHHHHHHTT-CSSHH
T ss_pred             CCHH------------------------------------------------H-HHHHHhhchhHHHHHHHHhc-CCCHH
Confidence            2000                                                0 00000012346777888887 46777


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTR  642 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~  642 (747)
                      ++..++.+|.+++.....      ...+...++++.+..++.+.++.++..++.+|.+++..... ......++++.+..
T Consensus       252 ~~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~  325 (563)
T 6KBN_C          252 VKCQATLALRNLASDTSY------QLEIVRAGGLPHLVKLIQSDSIPLVLASVACIRNISIHPLNEGLIVDAGFLKPLVR  325 (563)
T ss_dssp             HHHHHHHHHHHHTTSHHH------HHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHHTSGGGHHHHHHTTCHHHHHH
T ss_pred             HHHHHHHHHHHHhCChhH------HHHHHHCCcHHHHHHHHhCCCHHHHHHHHHHHHHHhcCcchHHHHHHCCcHHHHHH
Confidence            888999999998875321      22334567888888888888888999999999999876433 23344567788888


Q NP_000290.2     643 LLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       643 LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++...     .++.++..++.+|.+++...+.....+...++++.+..++.+. ++.++..++.++..+...
T Consensus       326 ~l~~~-----~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~l~~l~~~  391 (563)
T 6KBN_C          326 LLDYK-----DSEEIQCHAVSTLRNLAASSEKNRKEFFESGAVEKCKELALDS-PVSVQSEISACFAILALA  391 (563)
T ss_dssp             HTTCS-----SCHHHHHHHHHHHHHHHHHCSTTSHHHHTTCHHHHHHHHHTSS-CHHHHHHHHHHHHHHTTC
T ss_pred             HhCCC-----CCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHhCC-CHHHHHHHHHHHHHHhcC
Confidence            87652     2478888999999999876444444455555677777776654 556666666666655543


No 69
>2Z6G_A B-catenin; Full-Length, Beta-Catenin, CELL ADHESION; 3.4A {Danio rerio}
Probab=97.75  E-value=1.2e-08  Score=115.80  Aligned_cols=373  Identities=17%  Similarity=0.153  Sum_probs=224.6  Template_Neff=10.700

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      ..+++.+...+.+.++.++..++.+|..+..............+++..+...+.+ .+..++..++.+|..+..... ..
T Consensus       149 ~~~l~~L~~lL~~~~~~vr~~a~~~L~~l~~~~~~~~~~~~~~~~i~~L~~~L~~~~~~~vr~~a~~~L~~l~~~~~-~~  227 (780)
T 2Z6G_A          149 TRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTSGTLHNLSHHRE-GL  227 (780)
T ss_pred             cChHHHHHHHccCCCHHHHHHHHHHHHHHhCChHHHHHHHhCCCHHHHHHHHhcCCCCHHHHHHHHHHHHHHhCCHH-HH
Confidence            3566777777877788899999999998876532221111122466777777765 677888889999988875422 22


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELI-A-DALPVLADRVIIPFSGWCDGNSNMSREVVDP  400 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lv-e-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~  400 (747)
                      ..+...++++.+..++. ..++.++..++.+|..++.........+ . ++++.|+.++..+                ++
T Consensus       228 ~~~~~~~~i~~L~~lL~-~~~~~v~~~al~~L~~l~~~~~~~~~~~~~~~~~~~L~~lL~~~----------------~~  290 (780)
T 2Z6G_A          228 LAIFKSGGIPALVNMLG-SPVDSVLFHAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKT----------------NV  290 (780)
T ss_pred             HHHHHCCcHHHHHHHhC-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCC----------------CH
Confidence            22333567778888886 5567788899999998886533222222 2 6677777766531                34


Q NP_000290.2     401 EVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH  480 (747)
Q Consensus       401 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  480 (747)
                      ++-..+..+|..-....                    ...+..+. ..+++..|...+...     .+.+-.+.++.+|.
T Consensus       291 ~v~~~a~~~L~~l~~~~--------------------~~~~~~~~-~~~~~~~L~~~l~~~-----~~~~v~~~a~~~L~  344 (780)
T 2Z6G_A          291 KFLAITTDCLQILAYGN--------------------QESKLIIL-ASGGPQALVNIMRTY-----TYEKLLWTTSRVLK  344 (780)
T ss_pred             HHHHHHHHHHHHHHcCC--------------------HHHHHHHH-HCCcHHHHHHHhCCC-----CCHHHHHHHHHHHH
Confidence            44455555554311100                    00011110 123444444333221     01112222222332


Q NP_000290.2     481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSK  560 (747)
Q Consensus       481 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~  560 (747)
                      +++...                                                   .....+.+.++++.|+.++. +.
T Consensus       345 ~l~~~~---------------------------------------------------~~~~~~~~~~~l~~L~~~l~-~~  372 (780)
T 2Z6G_A          345 VLSVCS---------------------------------------------------SNKPAIVEAGGMQALGLHLT-DP  372 (780)
T ss_pred             HHhCCH---------------------------------------------------HHHHHHHHCCHHHHHHHHcc-CC
Confidence            222100                                                   00112245667888888887 46


Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFP  638 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~  638 (747)
                      +..++..++.+|.+++.....      ..  ...++++.|+.++.+.+..++..++.+|.+++.. ... ..+...++++
T Consensus       373 ~~~v~~~al~~L~~l~~~~~~------~~--~~~~~l~~L~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~l~  444 (780)
T 2Z6G_A          373 SQRLVQNCLWTLRNLSDAATK------QE--GMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIE  444 (780)
T ss_pred             CHHHHHHHHHHHHHHhcCCCC------HH--HHcChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHH
Confidence            778888999999999864321      11  1256788888888888888999999999999876 222 2334456777


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL---AKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~---~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      .|+..+...    ..++.++..++.+|.+++...+..   ...+...++++.|+.++....+..++..++.+|.+++...
T Consensus       445 ~L~~~l~~~----~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~i~~L~~ll~~~~~~~v~~~a~~~L~~l~~~~  520 (780)
T 2Z6G_A          445 ALVRTVLRA----GDREDITEPAICALRHLTSRHQDAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCP  520 (780)
T ss_pred             HHHHHHhcC----CCCHHHHHHHHHHHHHHHcCCccHHHHHHHHHHCCcHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCH
Confidence            777766521    035678899999999998653221   2223334567888888875435678899999999988776


Q NP_000290.2     716 ELQGVLRQQ  724 (747)
Q Consensus       716 ~~~~~~~~~  724 (747)
                      +....+...
T Consensus       521 ~~~~~~~~~  529 (780)
T 2Z6G_A          521 ANHAPLREQ  529 (780)
T ss_pred             HHHHHHHhC
Confidence            654444333


No 70
>5EWP_B Uncharacterized protein; translocation and attachment of rhoptries; 1.8A {Plasmodium falciparum Santa Lucia}
Probab=97.73  E-value=1.3e-08  Score=96.81  Aligned_cols=118  Identities=16%  Similarity=0.189  Sum_probs=81.2  Template_Neff=11.800

Q NP_000290.2     263 AIGAYYIQHTCFQ--DESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRR  340 (747)
Q Consensus       263 ~sAL~aLsnLs~~--~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll~lL~s  340 (747)
                      ..++.++.++...  .......+...+.++.+..++...+..++..++.++.+++.........+...+.++.++.++. 
T Consensus        60 ~~~~~~l~~l~~~~~~~~~~~~~~~~g~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~-  138 (252)
T 5EWP_B           60 ALSATQLAILASKENEPHYKDAIREANGIAVFINLLKSHELDRVHAAVVALSFLSVDNVKNCICMFESGALPYLISGMK-  138 (252)
T ss_dssp             HHHHHHHHHHHTCTTCTHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTTCHHHHHHHHHTTCHHHHHHHTT-
T ss_pred             HHHHHHHHHHhcCCCCHHHHHHHHHcccHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHhh-
Confidence            4677788777754  2333344445567788888887777778889999999988654444444444567777888776 


Q NP_000290.2     341 TGNAEIQKQLTGLLWNLSST-DELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       341 s~d~eVr~~AL~aLsnLas~-~~~~~~Lve-giLe~Lv~LL~~  381 (747)
                      ..++.++..++.++.+++.. ......+.+ ++++.|+.++..
T Consensus       139 ~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~  181 (252)
T 5EWP_B          139 SNIDGMKAACAQTCRNIFVLDKKYKKEFLKLGGITQLVNLLEL  181 (252)
T ss_dssp             CSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHTTSC
T ss_pred             CCCHHHHHHHHHHHHHHHhcCHHHHHHHHHCChHHHHHHHhcC
Confidence            55678889999999999864 333334444 777888877764


No 71
>5XGC_A Rap1 GTPase-GDP dissociation stimulator 1; armadillo GEF, ONCOPROTEIN; 2.1A {Homo sapiens}
Probab=97.72  E-value=1.3e-08  Score=103.51  Aligned_cols=358  Identities=19%  Similarity=0.180  Sum_probs=198.3  Template_Neff=13.200

Q NP_000290.2     257 QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVS  336 (747)
Q Consensus       257 sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll~  336 (747)
                      .++.++..++.++..+.... .....+...++++.+...+.+.++.++..++.++..++...+.....+...++++.+..
T Consensus         5 ~~~~~~~~a~~~l~~l~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~   83 (503)
T 5XGC_A            5 SQSSCKAKVANIIAEVAKNE-FMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVK   83 (503)
T ss_dssp             -------------------C-CCCCCSSCHHHHHHHHHHTTCSCHHHHHHHHHHHHHSCCCSHHHHHHHHHTTHHHHHHH
T ss_pred             chHHHHHHHHHHHHHHhcCh-hhhhhhhhcCcHHHHHHHHcCCCHHHHHHHHHHHHHHHcCCchHHHHHHHCChHHHHHH
Confidence            34567777888888887642 22333444567788888888778888999999999988654333333444567778888


Q NP_000290.2     337 LLRRT-GNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRL  414 (747)
Q Consensus       337 lL~ss-~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  414 (747)
                      .+... .++.++..++.++..++........+.. ++++.|+.++....               ++++-..+..+|..- 
T Consensus        84 ~l~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~~---------------~~~~~~~a~~~l~~l-  147 (503)
T 5XGC_A           84 LLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQI---------------EHDKREMIFEVLAPL-  147 (503)
T ss_dssp             HHHHTTTCHHHHHHHHHHHHHHTTSHHHHHHHTTTTHHHHHHHHHHHCC---------------CHHHHHHHHHHHHHH-
T ss_pred             HHhccCCCHHHHHHHHHHHHHHHccHHHHHHHhcCCHHHHHHHHHHhcC---------------ChhHHHHHHHHHHHH-
Confidence            87622 3677888999999998876443333333 67777777776421               233333333333211 


Q NP_000290.2     415 GMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRY  494 (747)
Q Consensus       415 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  494 (747)
                                          ...+..+..+. -.|.+..++..+...      ++.........+.+...          
T Consensus       148 --------------------~~~~~~~~~~~-~~~~~~~l~~~l~~~------~~~~~~~~~~~l~~~~~----------  190 (503)
T 5XGC_A          148 --------------------AENDAIKLQLV-EAGLVECLLEIVQQK------VDSDKEDDITELKTGSD----------  190 (503)
T ss_dssp             --------------------TTSHHHHHHHH-HTTHHHHHHHHHHHH------TTCCCHHHHHHHHHHHH----------
T ss_pred             --------------------HcCHHHHHHHH-HCCHHHHHHHHHHhc------CCCCCHHHHHHHHHHHH----------
Confidence                                11111111111 123444444433221      11111111111100000          


Q NP_000290.2     495 RQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSD---AIRTYLNLMGKSKKDATLEACAGA  571 (747)
Q Consensus       495 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G---~I~~LL~LL~ss~d~eVr~~AL~a  571 (747)
                                        .+.+-    ...         .+.   ...+...+   .++.++.++. +.++.++..++.+
T Consensus       191 ------------------~~~~~----~~~---------~~~---~~~~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~  235 (503)
T 5XGC_A          191 ------------------LMVLL----LLG---------DES---MQKLFEGGKGSVFQRVLSWIP-SNNHQLQLAGALA  235 (503)
T ss_dssp             ------------------HHHHH----TTS---------HHH---HHHHHGGGTCHHHHHHHHHTT-SSCHHHHHHHHHH
T ss_pred             ------------------HHHHH----HhC---------Cch---HHHHHhcCcccHHHHHHHHcc-CCCHHHHHHHHHH
Confidence                              00000    000         000   01112222   6777888887 4677888899999


Q NP_000290.2     572 LQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ----SGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTS  646 (747)
Q Consensus       572 L~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~----s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s  646 (747)
                      |.+++.....      ...+.+.++++.|+.++.    +.+..++..++.+|.+++..... ..+...++++.+..++.+
T Consensus       236 L~~l~~~~~~------~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~  309 (503)
T 5XGC_A          236 IANFARNDAN------CIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKS  309 (503)
T ss_dssp             HHHHCSSHHH------HHHHHHTTHHHHHHHHHHTTTTTCCHHHHHHHHHHHHHHTCSHHHHHHHHHHTHHHHHHTTTTC
T ss_pred             HHHHHCChhH------HHHHHHCCHHHHHHHHHHhccccCCHHHHHHHHHHHHHhcCCHHHHHHHHHcCHHHHHHHHHcC
Confidence            9999874321      333456688888988887    56788899999999999876433 333445678888888876


Q NP_000290.2     647 HTGNTSNSEDILSSACYTVRNLMASQPQLAKQYF-SSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       647 ~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lv-e~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                            .++.++..++++|.+++...+.....+. ..++++.++.++.+.....++..++.+|.+++...
T Consensus       310 ------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~  373 (503)
T 5XGC_A          310 ------EMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHS  373 (503)
T ss_dssp             ------CCHHHHHHHHHHHHHHTTTCHHHHHHHHTCHHHHHHHHHHHTCTTCHHHHHHHHHHHHHHHHHH
T ss_pred             ------CCHHHHHHHHHHHHHHHccCHHHHHHHccccchHHHHHHHHccCCccchHHHHHHHHHHHHHHc
Confidence                  3678899999999999875433333332 24567788888776523378888999998886544


No 72
>6BW9_A Importin subunit alpha-3, Protein W; Complex, Hendra virus, Importin, Karyopherin; 1.6A {Homo sapiens}
Probab=97.70  E-value=1.6e-08  Score=102.40  Aligned_cols=367  Identities=16%  Similarity=0.162  Sum_probs=222.4  Template_Neff=12.900

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTN  321 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~  321 (747)
                      ...++.+...+.+.++.++..++.++..+...... ....+...++++.+...+. ..++.++..++.++..++......
T Consensus         8 ~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~   87 (459)
T 6BW9_A            8 NTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQ   87 (459)
T ss_dssp             --CHHHHHHHHTCSSHHHHHHHHHHHHHHHHSSSSCCHHHHHHTTHHHHHHHHTTCTTCHHHHHHHHHHHHHHTTSCHHH
T ss_pred             ccchHHHHHhccccCHHHHHHHHHHHHHHhcCCCCCCHHHHHHCChHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHH
Confidence            34556667777777788899999999888764321 1122333456777777776 456778888999998887654433


Q NP_000290.2     322 KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVD  399 (747)
Q Consensus       322 ~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~  399 (747)
                      ...+...++++.+...+. +.++.++..++.++..++... .....+.. ++++.++.++...               .+
T Consensus        88 ~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~~  151 (459)
T 6BW9_A           88 TQAVVQSNAVPLFLRLLH-SPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPS---------------IP  151 (459)
T ss_dssp             HHHHHHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHTCSTT---------------SC
T ss_pred             HHHHhhCCHHHHHHHHhc-CCChHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHhccCCC---------------CC
Confidence            333334457777888776 556788889999999887652 22222333 5666666666421               12


Q NP_000290.2     400 PEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVL  479 (747)
Q Consensus       400 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  479 (747)
                      +++-..+..++..-                     ..............+++..+...+..      .+..-...+...|
T Consensus       152 ~~~~~~a~~~l~~l---------------------~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l  204 (459)
T 6BW9_A          152 ITFLRNVTWVMVNL---------------------CRHKDPPPPMETIQEILPALCVLIHH------TDVNILVDTVWAL  204 (459)
T ss_dssp             HHHHHHHHHHHHHH---------------------HCCCSSCCCHHHHHHHHHHHHHHTTC------CCHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH---------------------hcCCCCCCCHHHHHHHHHHHHHHHhc------CCHHHHHHHHHHH
Confidence            33333333332211                     10000001111223344444433321      1112222223233


Q NP_000290.2     480 HNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKS  559 (747)
Q Consensus       480 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss  559 (747)
                      .++...-                                                  ......+.+.++++.++.++. +
T Consensus       205 ~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~  233 (459)
T 6BW9_A          205 SYLTDAG--------------------------------------------------NEQIQMVIDSGIVPHLVPLLS-H  233 (459)
T ss_dssp             HHHHTSC--------------------------------------------------HHHHHHHHHTTCHHHHGGGGG-C
T ss_pred             HHHhhcC--------------------------------------------------hHHHHHHHhCChHHHHHHHcC-C
Confidence            3322100                                                  001112244567788888887 4


Q NP_000290.2     560 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVF  637 (747)
Q Consensus       560 ~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI  637 (747)
                      .++.++..++.+|.+++...+.     ....+.+.++++.+..++.+.++.++..++.+|.+++... .. ......+++
T Consensus       234 ~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~  308 (459)
T 6BW9_A          234 QEVKVQTAALRAVGNIVTGTDE-----QTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLV  308 (459)
T ss_dssp             SSHHHHHHHHHHHHHHTTSCHH-----HHHHHHTTTGGGGCHHHHTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCH
T ss_pred             CCHHHHHHHHHHHHHHHcCCHH-----HHHHHhcccchhcHHHHhhCCCHHHHHHHHHHHHHHcCCCHHHHHHHHHCCHH
Confidence            6778888999999999875332     2233344578888888888888889999999999998662 22 233445677


Q NP_000290.2     638 PEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQ-PQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       638 ~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s-~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      +.+..++.+      .++.++..++.+|.+++... ......+.+.++++.|..++.+. ++.++..++.+|.+++...+
T Consensus       309 ~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~a~~~l~~l~~~~~  381 (459)
T 6BW9_A          309 PMIIHLLDK------GDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVK-DAQVVQVVLDGLSNILKMAE  381 (459)
T ss_dssp             HHHHHHHHH------SCHHHHHHHHHHHHHHHHHCCHHHHHHHHHTTCHHHHHGGGGCS-CHHHHHHHHHHHHHHHHHCT
T ss_pred             HHHHHHHHh------CCHHHHHHHHHHHHHHHHhCCHHHHHHHHHCCcHHHHHHhcCCC-CHHHHHHHHHHHHHHHHHhH
Confidence            888888776      36778899999999998532 22333444456788888888766 77889999999999876544


No 73
>5D5K_C Importin subunit alpha-1, Poly [ADP-ribose]; PARP-2 NLS, PARP-2, poly(ADP-ribose)polymerase-2, Importin; 1.9A {Mus musculus}
Probab=97.66  E-value=2e-08  Score=101.26  Aligned_cols=364  Identities=17%  Similarity=0.188  Sum_probs=216.7  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.++..+. ..++.++..++.++..++...+.....+...++++.+...+.+.+..++..++.++..++.........
T Consensus        57 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  136 (466)
T 5D5K_C           57 LIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDL  136 (466)
T ss_dssp             HHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHH
T ss_pred             cHHHHHHHhhCCCChHHHHHHHHHHHHHcCCChHHHHHHhccchHHHHHHHhcCCCCcHHHHHHHHHHHHhcCCHHHHHH
Confidence            4555666665 345678888889998887654433334444567778888888777888999999999988654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAE-----IQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~e-----Vr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      +...++++.+...+. ..+..     ++..++.++..++..........  .++++.+..++..                
T Consensus       137 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------  199 (466)
T 5D5K_C          137 VIKHGAIDPLLALLA-VPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHH----------------  199 (466)
T ss_dssp             HHHTTCHHHHHHTTC-SSCGGGSCHHHHHHHHHHHHHHSCCCSSCCCHHHHHHHHHHHHHHTTS----------------
T ss_pred             HHHCCcHHHHHHHhh-CCCcccccHHHHHHHHHHHHHHHcCCCCCCChHHHHHHHHHHHHHHcC----------------
Confidence            334456677777775 33333     77788888888876433222221  2455666666542                


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                      .|+++...+..++..-....      +              .....+ --.+++..|...+..      .+..-...+..
T Consensus       200 ~~~~~~~~a~~~l~~l~~~~------~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~  252 (466)
T 5D5K_C          200 NDPEVLADSCWAISYLTDGP------N--------------ERIEMV-VKKGVVPQLVKLLGA------TELPIVTPALR  252 (466)
T ss_dssp             SCHHHHHHHHHHHHHHTSSC------H--------------HHHHHH-HTTTCHHHHHHHHTC------SCHHHHHHHHH
T ss_pred             CCHHHHHHHHHHHHHHhcCC------c--------------hHHHHH-HHCChHHHHHHHhcC------CCchHHHHHHH
Confidence            13444444444443211100      0              000000 012233333333221      11112222333


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      .|.++....                                                  ......+.+.++++.++.++.
T Consensus       253 ~l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~  282 (466)
T 5D5K_C          253 AIGNIVTGT--------------------------------------------------DEQTQKVIDAGALAVFPSLLT  282 (466)
T ss_dssp             HHHHHTTSC--------------------------------------------------HHHHHHHHHTTGGGGHHHHTT
T ss_pred             HHHHHhcCC--------------------------------------------------HHHHHHHHccChhHhHHHHhh
Confidence            333332100                                                  001112245567888888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGN  634 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~  634 (747)
                       +.++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.. . .. ..+...
T Consensus       283 -~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~  356 (466)
T 5D5K_C          283 -NPKTNIQKEATWTMSNITAGRQD-----QIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHC  356 (466)
T ss_dssp             -CSSHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTCHHHHHHHHHSSCHHHHHHHHHHHHHHHHHSCHHHHHHHHHT
T ss_pred             -CCCHHHHHHHHHHHHHHHcCCHH-----HHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHHHHhC
Confidence             46778888999999999875332     233334557888899988888888999999999999875 2 22 233445


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS------QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~------s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      ++++.+..++.+      .++.++..++.+|.+++..      .......+.+.++++.+..++.+. ++.++..++.++
T Consensus       357 ~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l  429 (466)
T 5D5K_C          357 GIIEPLMNLLSA------KDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHE-NESVYKASLNLI  429 (466)
T ss_dssp             TCHHHHHHGGGC------SCHHHHHHHHHHHHHHHHHHHHTTCHHHHHHHHHHTTHHHHHHHGGGCS-SHHHHHHHHHHH
T ss_pred             CcHHHHHHHhhc------CCHHHHHHHHHHHHHHHHHHHHhCCCHHHHHHHHHcCHHHHHHHHHhCC-cHHHHHHHHHHH
Confidence            577788888776      3678889999999999862      122333344456778888888766 788999999999


Q NP_000290.2     709 SDMWSSKE  716 (747)
Q Consensus       709 snL~~~~~  716 (747)
                      .+++...+
T Consensus       430 ~~l~~~~~  437 (466)
T 5D5K_C          430 EKYFSVEE  437 (466)
T ss_dssp             HHHC----
T ss_pred             HHhccCCc
Confidence            99887543


No 74
>4UAF_B Importin alpha 1 import receptor; importin karyopherin complex NLS, PROTEIN; HET: PO4; 1.698A {Mus musculus}
Probab=97.63  E-value=2.4e-08  Score=100.65  Aligned_cols=364  Identities=17%  Similarity=0.187  Sum_probs=219.0  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.++..+. ..++.++..++.++..++...+.....+...++++.+...+.+.+..++..++.++..++.........
T Consensus        57 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  136 (466)
T 4UAF_B           57 LIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDL  136 (466)
T ss_pred             cHHHHHHHhhCCCChHHHHHHHHHHHHHhcCChHHHHHHHccChHHHHHHHhcCCCCCHHHHHHHHHHHHhcCCHHHHHH
Confidence            4555666665 345678888888998887654433334444567778888888777888999999999988654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAE-----IQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~e-----Vr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      +...++++.+...+. .....     ++..++.++..++..........  .++++.+..++..                
T Consensus       137 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------  199 (466)
T 4UAF_B          137 VIKHGAIDPLLALLA-VPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHH----------------  199 (466)
T ss_pred             HHHCCcHHHHHHHhh-CCCcccccHHHHHHHHHHHHHHHcCCCCCCChhHHHHHHHHHHHHHcC----------------
Confidence            334456677777775 33333     77788888888876433222221  2555666666542                


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                      .|+++...+..++..-...      .+              .....+ --.+++..|...+..      .+..-...+..
T Consensus       200 ~~~~~~~~a~~~l~~l~~~------~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~  252 (466)
T 4UAF_B          200 NDPEVLADSCWAISYLTDG------PN--------------ERIEMV-VKKGVVPQLVKLLGA------TELPIVTPALR  252 (466)
T ss_pred             CCHHHHHHHHHHHHHHhcC------Cc--------------HHHHHH-HHCChHHHHHHHhcC------CChhHHHHHHH
Confidence            1344544444444321100      00              000000 012233333333221      11112222233


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      .|.++....                                                  ......+.+.++++.+..++.
T Consensus       253 ~l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~  282 (466)
T 4UAF_B          253 AIGNIVTGT--------------------------------------------------DEQTQKVIDAGALAVFPSLLT  282 (466)
T ss_pred             HHHHHhcCC--------------------------------------------------HHHHHHHhccCHHHHHHHHhc
Confidence            333332100                                                  001112245567888888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGN  634 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~  634 (747)
                       +.++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.. . .. ..+...
T Consensus       283 -~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~  356 (466)
T 4UAF_B          283 -NPKTNIQKEATWTMSNITAGRQD-----QIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHC  356 (466)
T ss_pred             -CCCHHHHHHHHHHHHHHhcCCHH-----HHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHHHHhC
Confidence             46778888999999999875332     233334557888899998888888999999999999875 2 22 233445


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS------QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~------s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      ++++.+..++.+      .++.++..++.+|.+++..      .+.....+.+.++++.+..++.+. ++.++..++.++
T Consensus       357 ~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l  429 (466)
T 4UAF_B          357 GIIEPLMNLLSA------KDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHE-NESVYKASLNLI  429 (466)
T ss_pred             CcHHHHHHHhhc------CCHHHHHHHHHHHHHHHHHHHHhCCChHHHHHHHHcCHHHHHHHHHhCC-CHHHHHHHHHHH
Confidence            577788888776      3678889999999999862      122333344456778888888766 788999999999


Q NP_000290.2     709 SDMWSSKE  716 (747)
Q Consensus       709 snL~~~~~  716 (747)
                      .+++...+
T Consensus       430 ~~l~~~~~  437 (466)
T 4UAF_B          430 EKYFSVEE  437 (466)
T ss_pred             HHHccCCc
Confidence            99887543


No 75
>3L6X_A Catenin delta-1, E-cadherin; p120, catenin, cadherin, E-cadherin, armadillo; HET: SO4; 2.4A {Homo sapiens}
Probab=97.63  E-value=2.7e-08  Score=108.38  Aligned_cols=364  Identities=16%  Similarity=0.179  Sum_probs=198.9  Template_Neff=11.000

Q NP_000290.2     263 AIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTG  342 (747)
Q Consensus       263 ~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~  342 (747)
                      ..++.+|..+....+.  ...+..+.++.++.++...++.++..++.+|..++.........+...++++.|+.++. ..
T Consensus        26 ~~~l~~L~~l~~~~~~--~~~~~~~~l~~li~~L~~~~~~v~~~a~~~L~~L~~~~~~~~~~~~~~g~i~~Lv~lL~-~~  102 (584)
T 3L6X_A           26 RGSLASLDSLRKGGPP--PPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD-HP  102 (584)
T ss_dssp             --------------CC--CCCCCCCCHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHGGG-CS
T ss_pred             cCchHHHHHHhcCCCC--CCcccCCcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCChHHHHHHHHCCcHHHHHHHhh-CC
Confidence            3445555555443221  11233467778888887777888999999999988544444444455567888888887 56


Q NP_000290.2     343 NAEIQKQLTGLLWNLSS--TDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMREL  419 (747)
Q Consensus       343 d~eVr~~AL~aLsnLas--~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  419 (747)
                      ++.++..++.+|.+++.  .......+.. ++++.|+.+|...               .|+++-..+.++|..       
T Consensus       103 ~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~i~~L~~ll~~~---------------~~~~v~~~a~~~L~~-------  160 (584)
T 3L6X_A          103 KKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKA---------------RDMDLTEVITGTLWN-------  160 (584)
T ss_dssp             SHHHHHHHHHHHHHHTSSSCHHHHHHHHHTTHHHHHHHHHHHC---------------CSHHHHHHHHHHHHH-------
T ss_pred             CHHHHHHHHHHHHHHhcCCCHHHHHHHHcCChHHHHHHHHHHc---------------CCHHHHHHHHHHHHH-------
Confidence            67899999999999987  3344444444 7888888888731               134444455555432       


Q NP_000290.2     420 LALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEY  499 (747)
Q Consensus       420 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  499 (747)
                                    |++.+..+..+...  .+..|...+........   ...+               +..    .+. 
T Consensus       161 --------------L~~~~~~~~~l~~~--~l~~L~~~l~~~~~~~~---~~~~---------------~~~----~~~-  201 (584)
T 3L6X_A          161 --------------LSSHDSIKMEIVDH--ALHALTDEVIIPHSGWE---REPN---------------EDC----KPR-  201 (584)
T ss_dssp             --------------HTTSGGGHHHHHHH--THHHCCCCCCHHHHCCC---------------------------------
T ss_pred             --------------HhcCHHHHHHHHHH--HHHHHHHhccccCCCCC---CCCC---------------cCC----CCc-
Confidence                          11111122222211  22233322221110000   0000               000    000 


Q NP_000290.2     500 NARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYH-SDAIRTYLNLMGK-----SKKDATLEACAGALQ  573 (747)
Q Consensus       500 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve-~G~I~~LL~LL~s-----s~d~eVr~~AL~aL~  573 (747)
                      ...+........+|+.|-+.               .+......+.+ .++++.|+.++..     ..+..++..++.+|.
T Consensus       202 ~~~~~~v~~~a~~~L~~l~~---------------~~~~~~~~l~~~~g~v~~L~~~l~~~~~~~~~~~~~~~~a~~~L~  266 (584)
T 3L6X_A          202 HIEWESVLTNTAGCLRNVSS---------------ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR  266 (584)
T ss_dssp             CCCCHHHHHHHHHHHHHHTS---------------SCHHHHHHHHHSTTHHHHHHHHHHHHHHTTCCSCHHHHHHHHHHH
T ss_pred             ccChHHHHHHHHHHHHHHhc---------------CCHHHHHHHHhCCCHHHHHHHHHHHHhcCCCCChHHHHHHHHHHH
Confidence            00000111112222222211               00011111223 4667888887762     125667778888888


Q NP_000290.2     574 NLTASKGLMS--------------------SGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRH-----PL  627 (747)
Q Consensus       574 nLs~~s~~~s--------------------~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~-----~e  627 (747)
                      +++.......                    .......+.+.++++.|+.++... ++.++..++.+|.+|+..     ..
T Consensus       267 ~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~ll~~~~~~~~~~~a~~~L~~L~~~~~~~~~~  346 (584)
T 3L6X_A          267 NLSYQVHREIPQAERYQEAAPNVANNTGTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY  346 (584)
T ss_dssp             HHHTTHHHHSTTCCC--------------CCCCGGGGGGSHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHSSCSHHHHH
T ss_pred             HHHhhhhccChhHHHHHHhcCcCCCCCCCCChhhhhHhhChhHHHHHHHHHHcCCCHHHHHHHHHHHHHHhCCCccCCHH
Confidence            8876421000                    000122334568888899988875 788999999999999874     22


Q NP_000290.2     628 L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA-------SPK  699 (747)
Q Consensus       628 ~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~-------d~e  699 (747)
                      . ..+...++++.|+.++..      .+..++..++++|.+|+.. +.....+. .++++.|+.++....       +..
T Consensus       347 ~~~~~~~~~~l~~L~~ll~~------~~~~v~~~a~~~L~~L~~~-~~~~~~l~-~~~l~~L~~~L~~~~~~~~~~~~~~  418 (584)
T 3L6X_A          347 IRSALRQEKALSAIADLLTN------EHERVVKAASGALRNLAVD-ARNKELIG-KHAIPNLVKNLPGGQQNSSWNFSED  418 (584)
T ss_dssp             HHHHHTSHHHHHHHHHGGGC------SCHHHHHHHHHHHHHHHTT-CSCHHHHH-HHHHHHHHHTSSSSSCSGGGTCCHH
T ss_pred             HHHHHHHcChHHHHHHHhcC------CCHHHHHHHHHHHHHHhcC-hHHHHHHH-cchHHHHHHcCCCCCCCCCcCCCHH
Confidence            2 233456788888888876      3678899999999999875 44444443 467888888776431       234


Q NP_000290.2     700 AAEAARLLLSDMWS  713 (747)
Q Consensus       700 Vr~aAL~aLsnL~~  713 (747)
                      ++..++.+|.+++.
T Consensus       419 ~~~~~l~~L~~l~~  432 (584)
T 3L6X_A          419 TVISILNTINEVIA  432 (584)
T ss_dssp             HHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHHHHh
Confidence            46778888888773


No 76
>4U5L_A deltaIBB-importin-alpha1; TPX2, inhibitor, TRANSPORT PROTEIN; HET: 3D6; 2.53A {Mus musculus}
Probab=97.60  E-value=2.9e-08  Score=98.47  Aligned_cols=367  Identities=14%  Similarity=0.181  Sum_probs=226.7  Template_Neff=13.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      ..++.+...+.+.++.++..++..+..+...... ....+...++++.+...+. ..++.++..++.++..++.......
T Consensus         5 ~~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~   84 (426)
T 4U5L_A            5 WSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQT   84 (426)
T ss_dssp             CCHHHHHHHHTSSCHHHHHHHHHHHHHHHHCSSCCCHHHHHHTTCHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHHH
T ss_pred             ccHHHHHhhccCCCHHHHHHHHHHHHHHHhcCCCccHHHHHHcCcHHHHHHHhccCCChHHHHHHHHHHHHHhCCCHHHH
Confidence            4556667777777888889999999888764322 1222333456777777776 4456788889999988876544333


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDP  400 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~  400 (747)
                      ..+...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.....           +..++
T Consensus        85 ~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~-----------~~~~~  152 (426)
T 4U5L_A           85 KAVVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDL-----------STLAC  152 (426)
T ss_dssp             HHHHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHHTCHHHHHHHHHTTCHHHHHHTTCSSCG-----------GGSCH
T ss_pred             HHHHhcCcHHHHHHHhc-CCChHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhhCCCC-----------chhhH
Confidence            33344467777888776 5677888999999999887543 2223333 677777777764211           11122


Q NP_000290.2     401 EVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH  480 (747)
Q Consensus       401 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  480 (747)
                      ++...+..++..-                     ..............+++..+...++.      .+..-...+...|.
T Consensus       153 ~~~~~~~~~l~~l---------------------~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~  205 (426)
T 4U5L_A          153 GYLRNLTWTLSNL---------------------CRNKNPAPPLDAVEQILPTLVRLLHH------NDPEVLADSCWAIS  205 (426)
T ss_dssp             HHHHHHHHHHHHH---------------------TCCCSSCCCHHHHHHHHHHHHHHTTS------SCHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHH---------------------HcCCCCCCCccHHHHHHHHHHHHHhC------CCHHHHHHHHHHHH
Confidence            2333333222211                     11111111111113344444333321      11122222222232


Q NP_000290.2     481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSK  560 (747)
Q Consensus       481 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~  560 (747)
                      ++...-.                                                  .....+.+.++++.++.++. +.
T Consensus       206 ~l~~~~~--------------------------------------------------~~~~~~~~~~~~~~l~~~l~-~~  234 (426)
T 4U5L_A          206 YLTDGPN--------------------------------------------------ERIEMVVKKGVVPQLVKLLG-AT  234 (426)
T ss_dssp             HHTSSCH--------------------------------------------------HHHHHHHTTTCHHHHHHHHT-CS
T ss_pred             HHhhCCc--------------------------------------------------HHHHHHhhcChHHHHHHHhc-CC
Confidence            2221100                                                  00111234567888888887 46


Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFP  638 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~  638 (747)
                      ++.++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.. +.. ..+...++++
T Consensus       235 ~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~  309 (426)
T 4U5L_A          235 ELPIVTPALRAIGNIVTGTDE-----QTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVP  309 (426)
T ss_dssp             CHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTGGGGHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHH
T ss_pred             CccHHHHHHHHHHHHhcCCHH-----HHHHHhccchHHHHHHHhcCCChHHHHHHHHHHHHHhcCCHHHHHHHHHCCHHH
Confidence            778888999999999875332     233334567888999999888889999999999999875 222 2334456778


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS-QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~-s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      .+..++.+      .++.++..++.+|.+++.. .+.....+.+.++++.+..++.+. ++.++..++.+|.+++.
T Consensus       310 ~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~  378 (426)
T 4U5L_A          310 FLVGVLSK------ADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAK-DTKIIQVILDAISNIFQ  378 (426)
T ss_dssp             HHHHHHHS------SCHHHHHHHHHHHHHHHHHCCHHHHHHHHHTTCHHHHHHGGGSC-CHHHHHHHHHHHHHHHH
T ss_pred             HHHHHhcC------CCHHHHHHHHHHHHHHHcCCCHHHHHHHHhCCcHHHHHHHhcCC-CHHHHHHHHHHHHHHHH
Confidence            88888876      3678889999999999874 233334455556788888888876 78899999999999976


No 77
>4MZ6_E Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin; ARM repeat, protein transport, Importin; 1.88A {Mus musculus}
Probab=97.58  E-value=3.4e-08  Score=101.56  Aligned_cols=364  Identities=17%  Similarity=0.184  Sum_probs=217.7  Template_Neff=12.800

Q NP_000290.2     246 TIPKAVQYLSSQ-DEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ss-d~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+. ++.++..++.++..++...+.....+...++++.+...+.+.++.++..++.++..++.........
T Consensus       101 ~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  180 (509)
T 4MZ6_E          101 LIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDL  180 (509)
T ss_dssp             HHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHH
T ss_pred             cHHHHHHHhcCCCChHHHHHHHHHHHHHhCCCHHHHHHHHhcChHHHHHHHhcCCChhHHHHHHHHHHHHhCCCHHHHHH
Confidence            455566666543 3678888889988887654443334444567788888888777888999999999888654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAE-----IQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~e-----Vr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      +...++++.+...+. .....     ++..++.++..++..........  .++++.+..++..                
T Consensus       181 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------  243 (509)
T 4MZ6_E          181 VIKHGAIDPLLALLA-VPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHH----------------  243 (509)
T ss_dssp             HHHTTCHHHHHHHTC-SSCGGGSCHHHHHHHHHHHHHHHCCCSSCCCHHHHHHHHHHHHHHTTC----------------
T ss_pred             HHHCCcHHHHHHHHh-CCChhhhhHHHHHHHHHHHHHHhcCCCCCCCHHHHHHHHHHHHHHHhC----------------
Confidence            334456677777775 33333     77788888888876432221111  2556666666542                


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                      .++++...+..++..-....      +              .....+ --.+++..|...++.      .+..-...+..
T Consensus       244 ~~~~v~~~a~~~l~~l~~~~------~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~  296 (509)
T 4MZ6_E          244 NDPEVLADSCWAISYLTDGP------N--------------ERIEMV-VKKGVVPQLVKLLGA------TELPIVTPALR  296 (509)
T ss_dssp             SCHHHHHHHHHHHHHHTSSS------H--------------HHHHHH-HTTTCHHHHHHHHTC------SCHHHHHHHHH
T ss_pred             CCHHHHHHHHHHHHHHhcCC------h--------------HHHHHH-hhCChHHHHHHHhcC------CCcchHHHHHH
Confidence            13444444444443211100      0              000000 012233333333321      11112222333


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      +|.++....                                                  ......+.+.++++.|..++.
T Consensus       297 ~L~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~  326 (509)
T 4MZ6_E          297 AIGNIVTGT--------------------------------------------------DEQTQKVIDAGALAVFPSLLT  326 (509)
T ss_dssp             HHHHHTTSC--------------------------------------------------HHHHHHHHHTTGGGGHHHHTT
T ss_pred             HHHHHhcCC--------------------------------------------------HHHHHHHHhCChHHHHHHHhh
Confidence            333322100                                                  001112245567788888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH--PLL-HRVMGN  634 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~--~e~-~~ll~~  634 (747)
                       +.++.++..++.+|.+++...+.     ....+...++++.|+.++.+.++.++..++.+|.+++..  ... ..+...
T Consensus       327 -~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~  400 (509)
T 4MZ6_E          327 -NPKTNIQKEATWTMSNITAGRQD-----QIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHC  400 (509)
T ss_dssp             -CSSHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHHHSSCHHHHHHHHHHHHHHHHHSCHHHHHHHHHT
T ss_pred             -CCCHHHHHHHHHHHHHHhcCCHH-----HHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHHHHhC
Confidence             46778888999999998875332     233334557888888888888888999999999999875  222 233445


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS------QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~------s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      ++++.+..++.+      .++.++..++.+|.+++..      .+.....+.+.++++.+..++.+. ++.++..++.+|
T Consensus       401 ~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l  473 (509)
T 4MZ6_E          401 GIIEPLMNLLSA------KDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHE-NESVYKASLNLI  473 (509)
T ss_dssp             TCHHHHHHGGGC------SCHHHHHHHHHHHHHHHHHHHHHTCHHHHHHHHHHTTHHHHHHHHTTCS-SHHHHHHHHHHH
T ss_pred             CCHHHHHHHHhC------CCHHHHHHHHHHHHHHHHHHHHcCCCchHHHHHHHcCHHHHHHHHHhCC-CHHHHHHHHHHH
Confidence            577888888776      3678888999999998862      123333344456788888888776 788999999999


Q NP_000290.2     709 SDMWSSKE  716 (747)
Q Consensus       709 snL~~~~~  716 (747)
                      ..+....+
T Consensus       474 ~~l~~~~~  481 (509)
T 4MZ6_E          474 EKYFSVEE  481 (509)
T ss_dssp             HHHCC---
T ss_pred             HHHCCCCc
Confidence            99886543


No 78
>5UMZ_B Importin subunit alpha-1, TNRC6A; mRNA decay, miRNA ARM repeat; HET: GOL; 1.9A {Mus musculus}
Probab=97.58  E-value=3.4e-08  Score=101.56  Aligned_cols=364  Identities=17%  Similarity=0.184  Sum_probs=219.0  Template_Neff=12.800

Q NP_000290.2     246 TIPKAVQYLSSQ-DEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ss-d~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+. ++.++..++.++..++...+.....+...++++.+...+.+.++.++..++.++..++.........
T Consensus       101 ~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  180 (509)
T 5UMZ_B          101 LIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDL  180 (509)
T ss_dssp             CHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHHHTCHHHHHH
T ss_pred             cHHHHHHHhcCCCChHHHHHHHHHHHHHhCCCHHHHHHHHhcChHHHHHHHhcCCChhHHHHHHHHHHHHhCCCHHHHHH
Confidence            455566666543 3678888889988887654443334444567788888888777888999999999888654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAE-----IQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~e-----Vr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      +...++++.+...+. .....     ++..++.++..++..........  .++++.+..++..                
T Consensus       181 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------  243 (509)
T 5UMZ_B          181 VIKHGAIDPLLALLA-VPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHH----------------  243 (509)
T ss_dssp             HHHTTCHHHHHHHTC-SSCGGGSCHHHHHHHHHHHHHHHCCCSSCCCHHHHHHHHHHHHHHTTS----------------
T ss_pred             HHHCCcHHHHHHHHh-CCChhhhhHHHHHHHHHHHHHHhcCCCCCCCHHHHHHHHHHHHHHHhC----------------
Confidence            334456677777775 33333     77788888888876432221111  2556666666542                


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                      .++++...+..++..-....      +              .....+ --.+++..|...++.      .+..-...+..
T Consensus       244 ~~~~v~~~a~~~l~~l~~~~------~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~  296 (509)
T 5UMZ_B          244 NDPEVLADSCWAISYLTDGP------N--------------ERIEMV-VKKGVVPQLVKLLGA------TELPIVTPALR  296 (509)
T ss_dssp             SCHHHHHHHHHHHHHHTSSC------H--------------HHHHHH-HTTTCHHHHHHHHTC------SCHHHHHHHHH
T ss_pred             CCHHHHHHHHHHHHHHhcCC------h--------------HHHHHH-hhCChHHHHHHHhcC------CCcchHHHHHH
Confidence            13444444444443211100      0              000000 012233333333321      11112222333


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      +|.++....                                                  ......+.+.++++.|..++.
T Consensus       297 ~L~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~  326 (509)
T 5UMZ_B          297 AIGNIVTGT--------------------------------------------------DEQTQKVIDAGALAVFPSLLT  326 (509)
T ss_dssp             HHHHHTTSC--------------------------------------------------HHHHHHHHHTTGGGGHHHHTT
T ss_pred             HHHHHhcCC--------------------------------------------------HHHHHHHHhCChHHHHHHHhh
Confidence            333322100                                                  001112245567788888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH--PLL-HRVMGN  634 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~--~e~-~~ll~~  634 (747)
                       +.++.++..++.+|.+++...+.     ....+...++++.|+.++.+.++.++..++.+|.+++..  ... ..+...
T Consensus       327 -~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~  400 (509)
T 5UMZ_B          327 -NPKTNIQKEATWTMSNITAGRQD-----QIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHC  400 (509)
T ss_dssp             -CSSHHHHHHHHHHHHHHHTSCHH-----HHHHHHHTTHHHHHHHHHHSSCHHHHHHHHHHHHHHHHHSCHHHHHHHHHT
T ss_pred             -CCCHHHHHHHHHHHHHHhcCCHH-----HHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHHHHhC
Confidence             46778888999999998875332     233334557888888888888888999999999999875  222 233445


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS------QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~------s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      ++++.+..++.+      .++.++..++.+|.+++..      .+.....+.+.++++.+..++.+. ++.++..++.+|
T Consensus       401 ~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l  473 (509)
T 5UMZ_B          401 GIIEPLMNLLSA------KDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHE-NESVYKASLNLI  473 (509)
T ss_dssp             TCHHHHHHGGGC------SCHHHHHHHHHHHHHHHHHHHHHTCHHHHHHHHHHTTHHHHHHHHHTCS-CHHHHHHHHHHH
T ss_pred             CCHHHHHHHHhC------CCHHHHHHHHHHHHHHHHHHHHcCCCchHHHHHHHcCHHHHHHHHHhCC-CHHHHHHHHHHH
Confidence            577888888776      3678888999999998862      123333344456788888888776 788999999999


Q NP_000290.2     709 SDMWSSKE  716 (747)
Q Consensus       709 snL~~~~~  716 (747)
                      ..+....+
T Consensus       474 ~~l~~~~~  481 (509)
T 5UMZ_B          474 EKYFSVEE  481 (509)
T ss_dssp             HHHCCCCC
T ss_pred             HHHCCCCc
Confidence            99886543


No 79
>5ZHX_D Rap1 GTPase-GDP dissociation stimulator 1; armadillo GEF chaperone, ONCOPROTEIN; HET: FAR; 3.5A {Homo sapiens}
Probab=97.57  E-value=3.6e-08  Score=99.74  Aligned_cols=332  Identities=20%  Similarity=0.193  Sum_probs=197.3  Template_Neff=13.200

Q NP_000290.2     282 QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTG--NAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       282 ~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~--d~eVr~~AL~aLsnLas  359 (747)
                      .+...++++.+...+.+.++.++..++.++..++...+.....+...++++.+...+. ..  ++.++..++.++..++.
T Consensus        13 ~l~~~~~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~i~~l~~~l~-~~~~~~~v~~~a~~~l~~l~~   91 (487)
T 5ZHX_D           13 PCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLG-IHCQNAALTEMCLVAFGNLAE   91 (487)
T ss_dssp             ---CHHHHHHHHHHTTCSCHHHHHHHHHHHHTTSTTCHHHHHHHHHTTCHHHHHHHHH-HTSSCSHHHHHHHHHHHHHTT
T ss_pred             HHhhcCcHHHHHHHHcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHHc-ccCCCHHHHHHHHHHHHHHHc
Confidence            3444567778888888778889999999999988654443334444567788888886 43  67888899999999887


Q NP_000290.2     360 TDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSAD  438 (747)
Q Consensus       360 ~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  438 (747)
                      .......+.. ++++.|+.++....               ++++-..+..+|..-                     ...+
T Consensus        92 ~~~~~~~~~~~~~~~~l~~~l~~~~---------------~~~~~~~a~~~l~~l---------------------~~~~  135 (487)
T 5ZHX_D           92 LESSKEQFASTNIAEELVKLFKKQI---------------EHDKREMIFEVLAPL---------------------AEND  135 (487)
T ss_dssp             SSHHHHHHHHTTHHHHHHHHHHHCC---------------SHHHHHHHHHHHHHH---------------------HTSH
T ss_pred             chhHHHHHhhCCHHHHHHHHHHhcc---------------ChHHHHHHHHHHHHH---------------------hcCH
Confidence            6443333333 67777777776431               333333333333211                     1111


Q NP_000290.2     439 AGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKS  518 (747)
Q Consensus       439 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  518 (747)
                      ..+..+. ..|.++.|+..+...      ++.........+.....                            .+.+..
T Consensus       136 ~~~~~~~-~~~~~~~l~~~l~~~------~~~~~~~~~~~l~~~~~----------------------------~~~~~~  180 (487)
T 5ZHX_D          136 AIKLQLV-EAGLVECLLEIVQQK------VDSDKEDDITELKTGSD----------------------------LMVLLL  180 (487)
T ss_dssp             HHHHHHH-HHTHHHHHHHHHHHT------SSCCCHHHHHHHHHHHH----------------------------HHHHHT
T ss_pred             HHHHHHH-HCCHHHHHHHHHHhc------CCCCCHHHHHHHHHHHH----------------------------HHHHHH
Confidence            1111111 123444444433321      11111111111110000                            000000


Q NP_000290.2     519 DKMMNNNYDCPLPEEETNPKGSGWLYHSD---AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEK  595 (747)
Q Consensus       519 ~~~~~~~~~~~~~~~~~ni~~~~~lve~G---~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~g  595 (747)
                          .+         .+.   ...+...+   .++.++.++. +.++.++..++.+|.+++....      ....+.+.+
T Consensus       181 ----~~---------~~~---~~~~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~------~~~~~~~~~  237 (487)
T 5ZHX_D          181 ----LG---------DES---MQKLFEGGKGSVFQRVLSWIP-SNNHQLQLAGALAIANFARNDA------NCIHMVDNG  237 (487)
T ss_dssp             ----TS---------HHH---HHHHSSSSSSSHHHHHHTTTT-SSCHHHHHHHHHHHHHHCCSHH------HHHHHHTTT
T ss_pred             ----hc---------cHH---HHHHhhCCCchHHHHHHHHcc-CCCHHHHHHHHHHHHHHHcCch------HHHHHHhcC
Confidence                00         000   01112222   6777888887 4677888899999999987432      133345567


Q NP_000290.2     596 GLPQIARLLQ----SGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       596 iI~~Ll~LL~----s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      +++.++.++.    +.+..++..++.+|.+++..... ..+...++++.+..++.+      .++.++..++++|.+++.
T Consensus       238 ~~~~l~~~l~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~  311 (487)
T 5ZHX_D          238 IVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKS------EMPPVQFKLLGTLRMLID  311 (487)
T ss_dssp             HHHHHHHHHHHTSSSSCHHHHHHHHHHHHHHTCSHHHHHHHHHHTHHHHHHTTSSC------CCHHHHHHHHHHHHHHTS
T ss_pred             HHHHHHHHHHhcccCCCHHHHHHHHHHHHHhcCChhhHHHHHHcChHHHHHHHHhC------CCHHHHHHHHHHHHHHHh
Confidence            8888888887    56788899999999999876433 233445677888888876      367889999999999987


Q NP_000290.2     671 SQPQLAKQYF-SSSMLNNIINLCRSSASP-KAAEAARLLLSDMWSSK  715 (747)
Q Consensus       671 ~s~e~~~~Lv-e~giL~~Ll~LL~s~~d~-eVr~aAL~aLsnL~~~~  715 (747)
                      ..+.....+. ..++++.++.++.+. +. .++..++.+|.+++...
T Consensus       312 ~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~a~~~l~~l~~~~  357 (487)
T 5ZHX_D          312 AQAEAAEQLGKNVKLVERLVEWCEAK-DHAGVMGESNRLLSALIRHS  357 (487)
T ss_dssp             SCHHHHHHHHHCHHHHHHHHHHHTCC-SCCHHHHHHHHHHHHHHHHH
T ss_pred             hcHHHHHHhccccCHHHHHHHHHHhc-CchhhHHHHHHHHHHHHHHh
Confidence            5433333333 245678888888765 44 78888999999986544


No 80
>3NOW_A SD10334p; Armadillo Repeat, Hsp90, Myosin, Tetra-tricopeptide; 2.992A {Drosophila melanogaster}
Probab=97.57  E-value=3.6e-08  Score=107.84  Aligned_cols=135  Identities=17%  Similarity=0.118  Sum_probs=82.7  Template_Neff=12.800

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.++.++..++.++..+... .... .....++++.+...+.+.+..++..++.++..+.........
T Consensus       289 ~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~-~~~~-~~~~~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~  366 (810)
T 3NOW_A          289 EGILQMILAMATTDDELQQRVACECLIAASSK-KDKA-KALCEQGVDILKRLYHSKNDGIRVRALVGLCKLGSYGGQDAA  366 (810)
T ss_dssp             TTHHHHHHHHHHSSCHHHHHHHHHHHHHHTTS-HHHH-HTTHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHHTTTTTTTS
T ss_pred             cChHHHHHHHccCCCHHHHHHHHHHHHHHhCC-HHHH-HHHHhhhHHHHHHHhcCCCHHHHHHHHHHHHHHHccCCcccc
Confidence            44556666677777788899999999888764 2111 122235677777777777788888999999888764332111


Q NP_000290.2     324 ET-RRQNGIREAVSLLRR-----TGNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVI  380 (747)
Q Consensus       324 ~l-l~~~IL~~Ll~lL~s-----s~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~  380 (747)
                      .. ...+.++.+...+..     +.++.++..++.++..++........+..  ++++.+..++.
T Consensus       367 ~~~~~~~~~~~l~~~l~~~l~~~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~  431 (810)
T 3NOW_A          367 IRPFGDGAALKLAEACRRFLIKPGKDKDIRRWAADGLAYLTLDAECKEKLIEDKASIHALMDLAR  431 (810)
T ss_dssp             CCSSTTTHHHHHHHHHHHHHHCSSCCSSHHHHHHHHHHHHTTSHHHHHHHHHCHHHHHHHHHHHH
T ss_pred             ccccCCCHHHHHHHHHHHHHhCCCCCHHHHHHHHHHHHHHcCCHHHHHHHHhChHHHHHHHHHHc
Confidence            11 122344445544431     24567888889999888765433333322  46666666665


No 81
>4EV8_A Catenin beta-1; mouse catenin, CELL ADHESION; HET: URE; 1.9A {Mus musculus}
Probab=97.55  E-value=4.1e-08  Score=100.94  Aligned_cols=137  Identities=25%  Similarity=0.276  Sum_probs=86.1  Template_Neff=13.100

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLR--SPNQNVQQAAAGALRNLVFRSTTN-  321 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~--s~d~eVr~~AL~aLs~La~~~~~~-  321 (747)
                      .+++.+...+.+.+..++..++.++..+..........+...+.++.+...+.  ..++.++..++.++..++...... 
T Consensus       267 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~~~~  346 (538)
T 4EV8_A          267 GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAE  346 (538)
T ss_pred             CcHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHHhcCCCCHHHHHHHHHHHHHHHcCCCChH
Confidence            34555666666666778888888888886544433333344556667776665  445677888888888887644321 


Q NP_000290.2     322 --KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       322 --~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~  381 (747)
                        .......++++.+...+....++.++..++.++..++........+.. ++++.|..++..
T Consensus       347 ~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~  409 (538)
T 4EV8_A          347 MAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVR  409 (538)
T ss_pred             HHHHHHHHCCHHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCHHHHHHHHHCChHHHHHHHHcC
Confidence              112222356677777775223567888888999888875444433444 677777776653


No 82
>5Z8H_A Adenomatous polyposis coli protein, Peptide; APC, inhibitor, PROTEIN BINDING-INHIBITOR complex; HET: PHQ, GOL; 1.79A {Homo sapiens}
Probab=97.54  E-value=4.4e-08  Score=95.72  Aligned_cols=161  Identities=21%  Similarity=0.247  Sum_probs=120.5  Template_Neff=12.500

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLK-EKGLPQIARLLQSGN----SDVVRSGASL  618 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie-~giI~~Ll~LL~s~d----~eVr~~AL~a  618 (747)
                      .+.++++.|+.++....++.++..++++|.+++...+.     ....+.. .++++.++.++...+    ..++..++++
T Consensus       162 ~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~  236 (339)
T 5Z8H_A          162 REVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTE-----NKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGI  236 (339)
T ss_pred             HHCCcHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHH-----HHHHHHHhcChHHHHHHHhcCCCCCCCHHHHHHHHHH
Confidence            45678888888887325677888899999999874332     2334455 688888988887543    6788889999


Q NP_000290.2     619 LSNMSR----HPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR  693 (747)
Q Consensus       619 LsnLa~----~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~  693 (747)
                      |.+++.    .+.. ..+...++++.++.++..      .++.++..++++|.+++...+.....+.+.++++.|..++.
T Consensus       237 l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~  310 (339)
T 5Z8H_A          237 LRNVSSLIATNEDHRQILRENNCLQTLLQHLKS------HSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIH  310 (339)
T ss_pred             HHHHHHhhccCHHHHHHHHHCCHHHHHHHHHhC------CCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHhh
Confidence            999873    2222 233445678888888866      36778999999999999844666666667788999999988


Q NP_000290.2     694 SSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       694 s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      +. ++.++..++.+|.+++...+
T Consensus       311 ~~-~~~v~~~a~~~l~~l~~~~~  332 (339)
T 5Z8H_A          311 SK-HKMIAMGSAAALRNLMANRP  332 (339)
T ss_pred             CC-CHHHHHHHHHHHHHHHcCCc
Confidence            76 78899999999999997654


No 83
>3SL9_B Catenin beta-1, B-cell CLL/lymphoma 9; Armadillo repeat, components of the; HET: GOL, EDO, PEG, IMD; 2.2A {Homo sapiens}
Probab=97.53  E-value=4.8e-08  Score=84.82  Aligned_cols=134  Identities=16%  Similarity=0.203  Sum_probs=89.6  Template_Neff=12.600

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQL-GGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~-~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .+++.+...+.+.++.++..++.++.++..... ....+... ++++.+..++.. .+..++..++.++.+++.. ....
T Consensus        13 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~-~~~~   90 (167)
T 3SL9_B           13 RAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEA-SRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHH-REGL   90 (167)
T ss_pred             CcHHHHHHHhCCCCHHHHHHHHHHHHHHccCHH-HHHHHHhCCchHHHHHHHHhcCCCHHHHHHHHHHHHHHcCC-HhHH
Confidence            345566666666677788889999998876543 22223332 377778887776 6677888899999888843 3333


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVII  381 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~~  381 (747)
                      ..+...+.++.+..++. ..++.++..++.++.+++........++.  ++++.|+.++..
T Consensus        91 ~~~~~~~~i~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~  150 (167)
T 3SL9_B           91 LAIFKSGGIPALVKMLG-SPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNK  150 (167)
T ss_pred             HHHHHCCcHHHHHHHhC-CCCHHHHHHHHHHHHHHHcCCHhHHHHHHHcCHHHHHHHHhcC
Confidence            33444567778888886 55677888899999998875443333332  677777777654


No 84
>4E4V_A Importin subunit alpha-2; armadillo repeat, karyopherin, importin, nuclear; HET: GOL, DTT; 2.5283A {Homo sapiens}
Probab=97.52  E-value=5e-08  Score=99.91  Aligned_cols=156  Identities=17%  Similarity=0.216  Sum_probs=117.7  Template_Neff=12.700

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++++.++.++. +.++.++..++.+|.+++.....     ....+...++++.+..++.+.++.++..++.+|.+++..
T Consensus       206 ~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~  279 (485)
T 4E4V_A          206 EQILPTLVRLLH-HDDPEVLADTCWAISYLTDGPNE-----RIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTG  279 (485)
T ss_dssp             HHHHHHHHHHTT-SCCHHHHHHHHHHHHHHTSSCHH-----HHHHHHTTTCHHHHHHHHTCSCHHHHHHHHHHHHHHTTS
T ss_pred             hcHHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCChH-----HhhHHhhCChHHHHHHHhcCCChHHHHHHHHHHHHHhcC
Confidence            356777888887 46778888999999998875332     223334567888899999888888999999999999876


Q NP_000290.2     626 P-LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       626 ~-e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                      . .. ......++++.+..++.+      .++.++..++.+|.+++...+.....+...++++.|+.++.+. ++.++..
T Consensus       280 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~  352 (485)
T 4E4V_A          280 TDEQTQVVIDAGALAVFPSLLTN------PKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKA-DFKTQKE  352 (485)
T ss_dssp             CHHHHHHHHHTTGGGGHHHHHTC------SSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHHHHS-CHHHHHH
T ss_pred             CHHHHHHHHhCChHHHHHHHhcC------CCHHHHHHHHHHHHHHcCCCHHHHHHHHHCCHHHHHHHHHhcC-CHHHHHH
Confidence            2 22 233445678888888876      3678899999999999876555555566667788888888766 7788889


Q NP_000290.2     704 ARLLLSDMWSS  714 (747)
Q Consensus       704 AL~aLsnL~~~  714 (747)
                      ++.+|.+++..
T Consensus       353 a~~~l~~l~~~  363 (485)
T 4E4V_A          353 AVWAVTNYTSG  363 (485)
T ss_dssp             HHHHHHHHHHH
T ss_pred             HHHHHHHHHhc
Confidence            99999888865


No 85
>1WA5_B GTP-BINDING NUCLEAR PROTEIN RAN, IMPORTIN; NUCLEAR TRANSPORT-COMPLEX, NUCLEAR TRANSPORT, EXPORTIN; HET: GTP; 2.0A {CANIS FAMILIARIS} SCOP: a.118.1.1
Probab=97.52  E-value=5.1e-08  Score=102.06  Aligned_cols=368  Identities=16%  Similarity=0.204  Sum_probs=223.8  Template_Neff=12.300

Q NP_000290.2     242 CSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLRSPN-QNVQQAAAGALRNLVFRST  319 (747)
Q Consensus       242 ~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~s~d-~eVr~~AL~aLs~La~~~~  319 (747)
                      .....++.++..+.+.++.++..++..+..++..... ....+...++++.+...+...+ +.++..++.+|..++....
T Consensus        84 ~~~~~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~L~~~l~~~~~~~v~~~a~~~L~~l~~~~~  163 (530)
T 1WA5_B           84 QLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTS  163 (530)
T ss_dssp             ---CCHHHHHHHHSCSSHHHHHHHHHHHHHHTCCSSSCSHHHHHHTTCHHHHHHTTSTTSCHHHHHHHHHHHHHHTTSCH
T ss_pred             HHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHcCCCCCCHHHHHHcChHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCH
Confidence            3445566666777777777888888888887653221 1223333457777777776543 6677888899988876443


Q NP_000290.2     320 TNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       320 ~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      .....+...++++.+...+. ..++.++..++.++..++... .....+.. ++++.|+.++...               
T Consensus       164 ~~~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~---------------  227 (530)
T 1WA5_B          164 AQTKVVVDADAVPLFIQLLY-TGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSN---------------  227 (530)
T ss_dssp             HHHHHHHHTTCHHHHHHHHH-HCCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHGGGSC---------------
T ss_pred             HHHHHHhcCChHHHHHHHHh-CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCcHHHHHHHhhCC---------------
Confidence            33333333466777777776 556788899999999988753 23333333 6777777776521               


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                       ++++...+..+|..-...                     ...........+++..|...+..      .+......+..
T Consensus       228 -~~~v~~~a~~~l~~l~~~---------------------~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~  279 (530)
T 1WA5_B          228 -KPSLIRTATWTLSNLCRG---------------------KKPQPDWSVVSQALPTLAKLIYS------MDTETLVDACW  279 (530)
T ss_dssp             -CHHHHHHHHHHHHHHHCC---------------------SSSCCCHHHHGGGHHHHHHHTTC------CCHHHHHHHHH
T ss_pred             -CHHHHHHHHHHHHHHHCC---------------------CCCCCCHHHHhhHHHHHHHHHhc------CCHHHHHHHHH
Confidence             344444444443221100                     00000011122334444333221      11111222222


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      .|.++...                                                  +......+.+.++++.|+.++.
T Consensus       280 ~l~~l~~~--------------------------------------------------~~~~~~~~~~~~~~~~l~~~l~  309 (530)
T 1WA5_B          280 AISYLSDG--------------------------------------------------PQEAIQAVIDVRIPKRLVELLS  309 (530)
T ss_dssp             HHHHHHSS--------------------------------------------------CHHHHHHHHHTTCHHHHHHGGG
T ss_pred             HHHHHcCC--------------------------------------------------CHHHHHHHHhCCHHHHHHHHhc
Confidence            22222110                                                  0001112345567778888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQ  635 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~g  635 (747)
                       ..++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++++|.+++... .. ..+...+
T Consensus       310 -~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~  383 (530)
T 1WA5_B          310 -HESTLVQTPALRAVGNIVTGNDL-----QTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDAN  383 (530)
T ss_dssp             -CSCHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTT
T ss_pred             -CCChhHHHHHHHHHHHHHhCCHH-----HHHHHHHCChHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCC
Confidence             46777888999999998875332     1223344578888999988888889999999999998762 22 3334456


Q NP_000290.2     636 VFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP---QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMW  712 (747)
Q Consensus       636 iI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~---e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~  712 (747)
                      +++.|..++.+      .++.++..++.+|.+++....   .....+.+.++++.|..++.+. ++.++..++.+|.+++
T Consensus       384 ~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~l~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~  456 (530)
T 1WA5_B          384 LIPPLVKLLEV------AEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIA-DNRIIEVTLDALENIL  456 (530)
T ss_dssp             CHHHHHHHHHH------SCHHHHHHHHHHHHHHHHHTTTCTHHHHHHHHTTCHHHHHHHTTTC-CHHHHHHHHHHHHHHH
T ss_pred             chHHHHHHHHc------CCHHHHHHHHHHHHHHHcCCCCCHHHHHHHHHCCCHHHHHHHccCC-CHHHHHHHHHHHHHHH
Confidence            77888888876      367889999999999987532   2334444557788888888866 7788999999999998


Q NP_000290.2     713 SSKE  716 (747)
Q Consensus       713 ~~~~  716 (747)
                      ...+
T Consensus       457 ~~~~  460 (530)
T 1WA5_B          457 KMGE  460 (530)
T ss_dssp             HHHH
T ss_pred             HHHH
Confidence            7654


No 86
>1EE4_A KARYOPHERIN ALPHA; ARM repeat, TRANSPORT PROTEIN; 2.1A {Saccharomyces cerevisiae} SCOP: a.118.1.1
Probab=97.51  E-value=5.1e-08  Score=96.57  Aligned_cols=115  Identities=13%  Similarity=0.098  Sum_probs=77.4  Template_Neff=13.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+....+.....+...++++.+...+.+.++.++..++.++..++.........
T Consensus        87 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  166 (423)
T 1EE4_A           87 DAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDW  166 (423)
T ss_dssp             THHHHHHHHHHHSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHHTTSCCHHHHHHHHHHHHHHHCCSTTCCCH
T ss_pred             ChHHHHHHHHhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCCCCCCh
Confidence            34556666676777888889999999887654433333444467777888887777888888999998887644222222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ....++++.+...+. ..++.++..++.++..+...
T Consensus       167 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  201 (423)
T 1EE4_A          167 SVVSQALPTLAKLIY-SMDTETLVDACWAISYLSDG  201 (423)
T ss_dssp             HHHGGGHHHHHHHTT-CSCHHHHHHHHHHHHHHTSS
T ss_pred             HHHhhHHHHHHHHHH-cCCHHHHHHHHHHHHHHhcC
Confidence            233455666666665 45567777778887777654


No 87
>1EE4_B KARYOPHERIN ALPHA; ARM repeat, TRANSPORT PROTEIN; 2.1A {Saccharomyces cerevisiae} SCOP: a.118.1.1
Probab=97.51  E-value=5.1e-08  Score=96.57  Aligned_cols=115  Identities=13%  Similarity=0.098  Sum_probs=77.4  Template_Neff=13.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+....+.....+...++++.+...+.+.++.++..++.++..++.........
T Consensus        87 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  166 (423)
T 1EE4_B           87 DAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDW  166 (423)
T ss_dssp             THHHHHHHHHHHSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHGGGSCCHHHHHHHHHHHHHHHCCSSSCCCH
T ss_pred             ChHHHHHHHHhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCCCCCCh
Confidence            34556666676777888889999999887654433333444467777888887777888888999998887644222222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ....++++.+...+. ..++.++..++.++..+...
T Consensus       167 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  201 (423)
T 1EE4_B          167 SVVSQALPTLAKLIY-SMDTETLVDACWAISYLSDG  201 (423)
T ss_dssp             HHHGGGHHHHHHHTT-CSCHHHHHHHHHHHHHHHSS
T ss_pred             HHHhhHHHHHHHHHH-cCCHHHHHHHHHHHHHHhcC
Confidence            233455666666665 45567777778887777654


No 88
>4I2Z_A Protein UNC-45, Heat shock protein; chaperone, myosin folding, protein filaments; 2.9A {Caenorhabditis elegans}
Probab=97.51  E-value=6.2e-08  Score=114.34  Aligned_cols=431  Identities=14%  Similarity=0.098  Sum_probs=219.4  Template_Neff=8.600

Q NP_000290.2     248 PKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE--T  325 (747)
Q Consensus       248 ~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~--l  325 (747)
                      +.++.++.+.+..++..++.+|.......... ..+. ...++.|..++.+.++.++..++..|..+..........  .
T Consensus       443 ~~l~~~~~~~~~~~~~~a~~~l~~~~~~~~~~-~~i~-~~~v~~L~~l~~~~~~~v~~~A~~~L~kL~~~~~~~~~~~~~  520 (961)
T 4I2Z_A          443 PIMLEMAASQDHLMQGIAAELIVATVSKHERA-INML-KVGIPVLRALYDSEDPTVKVRALVGLCKIGAAGGDDISKATM  520 (961)
T ss_dssp             HHHHHHHHSSCHHHHHHHHHHHHTTCCSSSSS-CHHH-HTHHHHHHHHHHCSSHHHHHHHHTTSSCC-------------
T ss_pred             HHHHHHhcCCCHHHHHHHHHHHHHHcChhHHH-HHHH-HhHHHHHHHHHhCCCHHHHHHHHHHHHHHHhcCCcchhhhcc
Confidence            33334455556667777777777554332111 1122 235677777777778889999999999887643321110  1


Q NP_000290.2     326 ---RRQNGIREAVSLLRRT--GNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVIIPFSGWCDGNSNMSREVV  398 (747)
Q Consensus       326 ---l~~~IL~~Ll~lL~ss--~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~~~~~~~~~~~~~~~~~~~  398 (747)
                         ....+...+..++...  .+..++..++..|..+.........+..  ++++.|++++...-+...-|       ++
T Consensus       521 ~~~~~~~L~~~~~~~l~~~~~~~~~~~~~A~e~Layls~~~~vke~l~~d~~~l~~L~~ll~~~~~~~~~~-------~~  593 (961)
T 4I2Z_A          521 KEEAVISLAKTCKKFLLETEKYSVDIRRYACEGLSYLSLDADVKEWIVDDSLLLKALVLLAKKAGALCVYT-------LA  593 (961)
T ss_dssp             ----CCHHHHHHHHHHHCTTTSCHHHHHHHHHHHHHHTTSHHHHHHHHHCHHHHHHHHHHHHHHGGGGSHH-------HH
T ss_pred             chHHHHHHHHHHHHHHhcCcCCChHHHHHHHHHHHHHhcCHHHHHHHhcCHHHHHHHHHHHHHcChhHHHH-------HH
Confidence               0112344444555411  2456888999999999876655555554  68888888887542111111       00


Q NP_000290.2     399 DPEVFFNATGCL-RKRLG--MRELLALVPQRATSSRVNLSSADAGRQTMR--NYSGLIDSLMAYVQNCVAASRCDDKSVE  473 (747)
Q Consensus       399 ~~~~~~~~~~~~-~~~~~--~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~~~~~~~~  473 (747)
                        ..+-|-+... ++.+.  |.+|..+..+.... ...+...+.-....+  --.|.+..|.+.+..      -+....+
T Consensus       594 --~~l~nl~~~~~~~~~~~e~~~l~~~a~~~~~~-~~~~d~~~~v~~r~~~l~~~g~~~~Lv~ll~~------~s~~~r~  664 (961)
T 4I2Z_A          594 --TIYANLSNAFEKPKVDEEMVKLAQFAKHHVPE-THPKDTEEYVEKRVRALVEEGAVPACVAVSKT------ESKNALE  664 (961)
T ss_dssp             --HHHHHHTTCCCCCC----------CCCCSSTT-CCTTSSTTHHHHHHHHHHHSCSHHHHHHTCCC------SCSHHHH
T ss_pred             --HHHHHHhcCCCCCCCCHHHHHHHHHHhcCCCC-CCcCCCHHHHHHHHHHHHHCCCHHHHHHHhcC------CCHHHHH
Confidence              0111111100 00000  11222221111110 000111111111111  113445555444432      1233445


Q NP_000290.2     474 NCMCVLHNLSYRLDAEVPTRYRQLEYNARNAY-------TE---KSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWL  543 (747)
Q Consensus       474 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-------~~---~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~l  543 (747)
                      .+..++++++-.-  +  .|-.-.+..+-..-       ++   .....+..+-..     .-+..+.+...        
T Consensus       665 ~~~~~l~~l~~~~--~--~R~~iv~~G~v~~Ll~ll~~~~~~~~~~Aa~ALa~l~~-----~~~p~~~~~~~--------  727 (961)
T 4I2Z_A          665 LIARSLLAFAEYE--D--LRGRIIAEGGTVLCLRLTKEASGEGKIKAGHAIAKLGA-----KADPMISFPGQ--------  727 (961)
T ss_dssp             HHHHHHHTTSCSS--T--THHHHTTTTHHHHHHHHHHHSCTHHHHHHHHHHHHHSS-----SSCSTTTSTTT--------
T ss_pred             HHHHHHHHHhCCH--H--HHHHHHHCchHHHHHHHHhcCChHHHHHHHHHHHHHHc-----cCChhhhcCCc--------
Confidence            5666777776211  1  11110111100000       00   000000000000     00000111111        


Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLSNM  622 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-s~d~eVr~~AL~aLsnL  622 (747)
                      ...++++.|+.+|..+.+...+..++.+|.+|+..++.     ....+.+.++++.|..+|. +.++.++..|+.++.+|
T Consensus       728 ~~~~~i~pLv~lL~~~~~~~~~~eal~ALtnLa~~~~~-----~~~~I~~~~~~~~l~~lL~~~~~~~vr~aA~ell~nL  802 (961)
T 4I2Z_A          728 RAYEVVKPLCDLLHPDVEGKANYDSLLTLTNLASVSDS-----IRGRILKEKAIPKIEEFWFMTDHEHLRAAAAELLLNL  802 (961)
T ss_dssp             HHHHTTSHHHHTTSCCSSCTTHHHHHHHHHHHHSSCHH-----HHHHHHHTTCHHHHGGGTSCSSCHHHHHHHHHHHHHS
T ss_pred             chhhHHHHHHHHhCCCCChHHHHHHHHHHHHHHcCCHH-----HHHHHHhcChHHHHHHHHhcCCCHHHHHHHHHHHHHH
Confidence            01267899999987334556778899999999986533     3445566788999999888 77889999999999999


Q NP_000290.2     623 SRHPLL-HRVM--GNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSS--SMLNNIINLCRSSAS  697 (747)
Q Consensus       623 a~~~e~-~~ll--~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~--giL~~Ll~LL~s~~d  697 (747)
                      +.++.. ..+.  ..+.+..++.++.+.     .+..++..|+.+|..++. .+.....+++.  +.+..+..++.+. +
T Consensus       803 ~~~~~~~~~~~~~~~~~~~ll~~l~~~~-----~d~~~~~aA~~aLa~ls~-~~~~~~~i~~~~~~~~~il~~ll~~~-~  875 (961)
T 4I2Z_A          803 LFFEKFYEETVAPGTDRLKLWVLYSAEV-----EEERLSRASAAGFAILTE-DENACARIMDEIKSWPEVFKDIAMHE-D  875 (961)
T ss_dssp             SSSTTSSTTTTSSCCTHHHHHHHHHHSC-----SSSTHHHHHHHHHHHHHT-CHHHHHHHTTTCTTHHHHHHHHHHCS-S
T ss_pred             HcCHHHHHhhCCCCCccchhhhHHhccC-----CCHHHHHHHHHHHHHHhC-CHHHHHHHHHHHhchHHHHHHHhhCC-C
Confidence            976544 2221  223444454443331     367888999999999884 46655555553  3466677777666 7


Q NP_000290.2     698 PKAAEAARLLLSDMWS-SKELQGVLRQQG  725 (747)
Q Consensus       698 ~eVr~aAL~aLsnL~~-~~~~~~~~~~~~  725 (747)
                      +.++..++.+|.+++. +.++...+-+.|
T Consensus       876 ~~l~~ra~~~L~nl~~~~~~~~~~i~~~g  904 (961)
T 4I2Z_A          876 AETQRRGLMGIANIMHSSNKLCSEIVSSE  904 (961)
T ss_dssp             TTHHHHHHHHHTTTSSSCHHHHTCCTTHH
T ss_pred             HHHHHHHHHHHHHHHhcCHHHHHHHHhcc
Confidence            8899999999999965 444444343344


No 89
>5XZX_A Importin subunit alpha-3, Ran-binding protein; nuclear import, TRANSPORT PROTEIN; 3.0A {Homo sapiens}
Probab=97.48  E-value=6.3e-08  Score=95.65  Aligned_cols=360  Identities=17%  Similarity=0.182  Sum_probs=211.7  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+. ..++.++..++.++..++...+.....+...++++.+...+.+.++.++..++.++..++...+.....
T Consensus        46 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  125 (416)
T 5XZX_A           46 ILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDY  125 (416)
T ss_dssp             CHHHHHHHTTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHH
T ss_pred             cHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCChHHHHHHHhcChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            4555666665 456678888888888887654433333334567777888887777888999999999887654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...+++..+...+....++.++..++.++..++..........  .++++.+..++..                .++++
T Consensus       126 ~~~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~~  189 (416)
T 5XZX_A          126 VISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHH----------------TDVNI  189 (416)
T ss_dssp             HHHHTCHHHHTTSCSTTSCHHHHHHHHHHHHHHHHCCSSCCCHHHHHHHHHHHHHHTTC----------------CCHHH
T ss_pred             HHHCccHHHHHHhcCCCCCHHHHHHHHHHHHHHhcCCCCCCChhHHHHHHHHHHHHHhC----------------CCHHH
Confidence            33345667777776533456778888888888876533211111  1566666666542                13444


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..++..-...      .+              .....+ --.+++..+...++.      -+..-...+...|.++
T Consensus       190 ~~~a~~~l~~l~~~------~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l  242 (416)
T 5XZX_A          190 LVDTVWALSYLTDA------GN--------------EQIQMV-IDSGIVPHLVPLLSH------QEVKVQTAALRAVGNI  242 (416)
T ss_dssp             HHHHHHHHHHHHHH------CH--------------HHHHHH-HHHTCHHHHGGGGGC------SCHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhhc------CH--------------HHHHHH-HHCChHHHHHHHcCC------CCHHHHHHHHHHHHHH
Confidence            44444333221100      00              000000 001334444333321      0111111222222222


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ...-                                                  ......+.+.++++.+..++. +.++
T Consensus       243 ~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~  271 (416)
T 5XZX_A          243 VTGT--------------------------------------------------DEQTQVVLNCDALSHFPALLT-HPKE  271 (416)
T ss_dssp             TTSC--------------------------------------------------HHHHHHHHTTTCGGGSHHHHT-CSCH
T ss_pred             HcCC--------------------------------------------------HHHHHHHcCcccHHHHHHHhc-CCCH
Confidence            1100                                                  001111234467788888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGNQVFPE  639 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~giI~~  639 (747)
                      .++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.. . .. ..+...++++.
T Consensus       272 ~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~  346 (416)
T 5XZX_A          272 KINKEAVWFLSNITAGNQQ-----QVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPP  346 (416)
T ss_dssp             HHHHHHHHHHHHHTTSCHH-----HHHHHHTTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHH
T ss_pred             HHHHHHHHHHHHHhcCCHH-----HHHHHHhCCHHHHHHHHHHcCCHHHHHHHHHHHHHHHHhcCHHHHHHHHHCCCHHH
Confidence            8888999999998765332     223334556888888888888888999999999999864 2 11 22334567788


Q NP_000290.2     640 VTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA----KQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDM  711 (747)
Q Consensus       640 Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~----~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL  711 (747)
                      +..++.+      .++.++..++.+|.+++...+...    ..+.+.++++.+..++.+. ++.++..++.+|.++
T Consensus       347 l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~~  415 (416)
T 5XZX_A          347 FCNLLTV------KDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHE-NEDIYKLAYEIIDQF  415 (416)
T ss_dssp             HHTTTTS------SCHHHHHHHHHHHHHHHHHCSTTHHHHHHHHHHTTHHHHHHTTCCTT-CHHHHHHHHHHHHHH
T ss_pred             HHHHccC------CCHHHHHHHHHHHHHHHHHhHHhHHHHHHHHHHcCHHHHHHHHhhCC-cHHHHHHHHHHHHHh
Confidence            8888776      367888899999999987533211    1233345677888888766 778888888887764


No 90
>5MFO_F YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: CA, EDO; 1.3A {synthetic construct}
Probab=97.46  E-value=6.9e-08  Score=85.28  Aligned_cols=134  Identities=25%  Similarity=0.287  Sum_probs=89.4  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++..+..++...+.....+...++++.+...+.+.++.++..++.++..++.........+
T Consensus         5 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~   84 (202)
T 5MFO_F            5 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV   84 (202)
T ss_dssp             THHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            34556666666777888889999988876544444444445677888888887778888999999999886544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus        85 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  140 (202)
T 5MFO_F           85 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLS  140 (202)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhc
Confidence            34456777777776 4566778888888888876422 2222223 55666666554


No 91
>3SL9_E Catenin beta-1, B-cell CLL/lymphoma 9; Armadillo repeat, components of the; HET: PEG, GOL, IMD, EDO; 2.2A {Homo sapiens}
Probab=97.46  E-value=7.2e-08  Score=83.64  Aligned_cols=134  Identities=16%  Similarity=0.201  Sum_probs=88.4  Template_Neff=12.600

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLG-GICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~-IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .+++.+...+.+.++.++..++.++.++..... ....+.... +++.+..++.. .+..++..++.++..++.. ....
T Consensus        13 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~-~~~~   90 (167)
T 3SL9_E           13 RAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEA-SRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHH-REGL   90 (167)
T ss_dssp             HHHHHHHHHHTCSCHHHHHHHHHHHHHHTTSHH-HHHHHHTCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTS-HHHH
T ss_pred             CcHHHHHHHhCCCCHHHHHHHHHHHHHHccCHH-HHHHHHhCCchHHHHHHHHhcCCCHHHHHHHHHHHHHHcCC-HhHH
Confidence            345556666666667788889999998876543 222233323 77777777776 6677888889999888743 3333


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVII  381 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~~  381 (747)
                      ..+...+.++.+..++. ..++.++..++.++.+++.........+.  ++++.|++++..
T Consensus        91 ~~~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~  150 (167)
T 3SL9_E           91 LAIFKSGGIPALVKMLG-SPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNK  150 (167)
T ss_dssp             HHHHHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHCTTHHHHHHHTTHHHHHHHHHHH
T ss_pred             HHHHHCCcHHHHHHHhC-CCCHHHHHHHHHHHHHHHcCCHhHHHHHHHcCHHHHHHHHhcC
Confidence            33444567777888776 55677888899999998875433333332  667777777654


No 92
>3NOW_A SD10334p; Armadillo Repeat, Hsp90, Myosin, Tetra-tricopeptide; 2.992A {Drosophila melanogaster}
Probab=97.46  E-value=7.3e-08  Score=105.35  Aligned_cols=110  Identities=10%  Similarity=0.050  Sum_probs=66.2  Template_Neff=12.800

Q NP_000290.2     247 IPKAVQYLSSQ--DEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       247 L~~Ll~lL~ss--d~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      +..++..+.+.  +..++..++..|..++... .........+.++.+...+.. .+..++..++.++..++........
T Consensus         8 i~~l~~~l~~~~~~~~~r~~a~~~l~~l~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~~~~~~~~~   86 (810)
T 3NOW_A            8 VKQMMDLTFDLATPIDKRRAAANNLVVLAKEQ-TGAELLYKDHCIAKVASLTKVEKDQDIYVNMVHLVAALCENSVERTK   86 (810)
T ss_dssp             HHHHHHHHHSSCCSSHHHHHHHHHHHHHSSCH-HHHHHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHHTTCHHHHH
T ss_pred             HHHHHHHHhcCCCcHHHHHHHHHHHHHHhccc-cccHHHHccccHHHHHHHhcCCCCHHHHHHHHHHHHHHHHcCHhHHH
Confidence            33445555554  5778888888888887654 222223334567777777731 5678888999999888765332222


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      .......++.+...+. ..++.++..++.++..++
T Consensus        87 ~~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~~~  120 (810)
T 3NOW_A           87 GVLTELGVPWFMRVLD-QKHENCVSTAQFCLQTIL  120 (810)
T ss_dssp             HHHHHSCHHHHHHHHH-CCSTTHHHHHHHHHHHHH
T ss_pred             HHHHHhcHHHHHHHhc-CCChhHHHHHHHHHHHHH
Confidence            2222334566666665 345556666666666554


No 93
>5MFO_E YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: EDO, CA; 1.3A {synthetic construct}
Probab=97.44  E-value=7.9e-08  Score=84.90  Aligned_cols=134  Identities=25%  Similarity=0.287  Sum_probs=89.3  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++..+..++...+.....+...++++.+...+.+.++.++..++.++..++.........+
T Consensus         5 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~   84 (202)
T 5MFO_E            5 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV   84 (202)
T ss_dssp             CHHHHHHHTTCSSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHHHHHHCChHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            34556666666777888889999988876544434444445677888888887788889999999999886544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus        85 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  140 (202)
T 5MFO_E           85 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLS  140 (202)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhc
Confidence            34456777777775 4566778888888888876422 2222223 55666666554


No 94
>4XZR_B Heh1-NLS, Kap60; karyopherins  nuclear import ; 2.25A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=97.44  E-value=8.1e-08  Score=95.04  Aligned_cols=115  Identities=13%  Similarity=0.098  Sum_probs=77.3  Template_Neff=13.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.++.++..++.++..++.........
T Consensus        87 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  166 (423)
T 4XZR_B           87 DAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDW  166 (423)
T ss_dssp             TCHHHHHHHHHHSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHHTTSCCHHHHHHHHHHHHHHHCCCTTCCCH
T ss_pred             chHHHHHHHHhCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCcHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCCCCCCh
Confidence            34556666677777888899999999887654433333444467777888887777888888999998887654222222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ....++++.+...+. ..++.++..++.++..++..
T Consensus       167 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  201 (423)
T 4XZR_B          167 SVVSQALPTLAKLIY-SMDTETLVDACWAISYLSDG  201 (423)
T ss_dssp             HHHGGGHHHHHHHTT-CSCHHHHHHHHHHHHHHTSS
T ss_pred             HHhccHHHHHHHHhh-CCCHHHHHHHHHHHHHHhcC
Confidence            233346666666665 44566777777777777654


No 95
>3OPB_A SWI5-dependent HO expression protein 4; HEAT and ARM fold, Myosin; 2.9A {Saccharomyces cerevisiae}
Probab=97.44  E-value=9.1e-08  Score=108.58  Aligned_cols=168  Identities=20%  Similarity=0.242  Sum_probs=116.3  Template_Neff=10.500

Q NP_000290.2     546 SDAIRTYLNLMGKSK-------------KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVV  612 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~-------------d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr  612 (747)
                      .++++.|+.++....             +..++..++.+|.+++.......+......+...++++.|..++.+.++.++
T Consensus       544 ~~~l~~L~~lL~~~~~~~~~~~~~~~~~~~~~~~~al~aL~~l~~~~~~~~~~~~~~~~~~~~~~~~L~~ll~~~~~~v~  623 (778)
T 3OPB_A          544 LNAIPFLFELLPRSTPVDDNPLHNDEQIKLTDNYEALLALTNLASSETSDGEEVCKHIVSTKVYWSTIENLMLDENVPLQ  623 (778)
T ss_dssp             TTHHHHHHHTSCCSSSCSSCC---CCCCCHHHHHHHHHHHHHHHHCCSHHHHHHHHHHHHSHHHHHHHHHGGGCSSHHHH
T ss_pred             cchHHHHHHHCCCCCCCCCCCCCChhhccHHHHHHHHHHHHHHhcCCCCCCHHHHHHHHhcccHHHHHHHHhhCCCHHHH
Confidence            456677777765211             4567778999999988752200000011222224688888888888888899


Q NP_000290.2     613 RSGASLLSNMSRHPLL--HRVMGN------QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFS-SS  683 (747)
Q Consensus       613 ~~AL~aLsnLa~~~e~--~~ll~~------giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve-~g  683 (747)
                      ..++.+|++++.....  ..++..      ++++.|+.++..      .+..++..++++|++++...+.....++. .+
T Consensus       624 ~~a~~~L~~L~~~~~~~~~~~~~~~~~~~~~~l~~L~~ll~~------~~~~v~~~a~~~L~~l~~~~~~~~~~l~~~~~  697 (778)
T 3OPB_A          624 RSTLELISNMMSHPLTIAAKFFNLENPQSLRNFNILVKLLQL------SDVESQRAVAAIFANIATTIPLIAKELLTKKE  697 (778)
T ss_dssp             HHHHHHHHHHHTSGGGTGGGTSCCSSHHHHHHHHHHHHGGGC------SCHHHHHHHHHHHHHHHHHCHHHHHHHTTCHH
T ss_pred             HHHHHHHHHHhcChhHHHHHhcCCCChhHHHhHHHHHHHhcC------CCHHHHHHHHHHHHHHHccCHHHHHHHhcCcc
Confidence            9999999999987432  233332      678888888876      36789999999999997655554444443 67


Q NP_000290.2     684 MLNNIINLCRSS-ASPKAAEAARLLLSDMWSSKELQG  719 (747)
Q Consensus       684 iL~~Ll~LL~s~-~d~eVr~aAL~aLsnL~~~~~~~~  719 (747)
                      +++.|+.++.+. .+..++..++++|.+++...+...
T Consensus       698 ~i~~L~~~L~~~~~~~~l~~~a~~aL~~L~~~~~~~~  734 (778)
T 3OPB_A          698 LIENAIQVFADQIDDIELRQRLLMLFFGLFEVIPDNG  734 (778)
T ss_dssp             HHHHHHHHHHHTTTCHHHHHHHHHHHHHHHTTCCSTT
T ss_pred             HHHHHHHHHHhCCCCHHHHHHHHHHHHHHHhhCCcCC
Confidence            889999998862 167789999999999997766544


No 96
>4I2W_A Protein UNC-45, Heat shock 70; chaperone, myosin folding, protein filaments; 3.6A {Caenorhabditis elegans}
Probab=97.43  E-value=1e-07  Score=112.49  Aligned_cols=433  Identities=14%  Similarity=0.102  Sum_probs=221.5  Template_Neff=8.600

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE--  324 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~--  324 (747)
                      ++.++.++.+.+..++..++.+|..+....... ..+. ...++.|..++.+.++.++..++..|..+..........  
T Consensus       442 ~~~l~~l~~~~~~~~~~~a~~~l~~~~~~~~~~-~~i~-~~~v~~L~~l~~~~~~~v~~~A~~~L~kL~~~~~~~~~~~~  519 (961)
T 4I2W_A          442 TPIMLEMAASQDHLMQGIAAELIVATVSKHERA-INML-KVGIPVLRALYDSEDPTVKVRALVGLCKIGAAGGDDISKAT  519 (961)
T ss_dssp             HHHHHHHHHSSCHHHHHTTTTTTTTTCCSCSSS-HHHH-HHHHHHHHHHHHCSCHHHHHHHHTTSSSCCC----------
T ss_pred             HHHHHHHhcCCCHHHHHHHHHHHHHHcChhHHH-HHHH-HhHHHHHHHHHhCCCHHHHHHHHHHHHHHHhcCCcchhhhc
Confidence            333334455556667777777777554332111 1122 235677777777778889999999999887543321100  


Q NP_000290.2     325 T---RRQNGIREAVSLLRRT--GNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       325 l---l~~~IL~~Ll~lL~ss--~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      .   ....+...+..++...  .+..++..++..|..+.........+..  .+++.|++++...-+...-|-       
T Consensus       520 ~~~~~~~~l~~~~~~~l~~~~~~~~~~~~~AvegLayLs~~~~vke~l~~d~~~l~~L~~ll~~~~~~~~~~~-------  592 (961)
T 4I2W_A          520 MKEEAVISLAKTCKKFLLETEKYSVDIRRYACEGLSYLSLDADVKEWIVDDSLLLKALVLLAKKAGALCVYTL-------  592 (961)
T ss_dssp             --CCCTTHHHHHHHHHHHCCSSSCHHHHHHHHHHHHHTCSSHHHHHHHHHCHHHHHHHHHHHHHHGGGSHHHH-------
T ss_pred             cchHHHHHHHHHHHHHHhcCcCCChHHHHHHHHHHHHHhcCHHHHHHHhcCHHHHHHHHHHHHHcChhHHHHH-------
Confidence            1   0112344455555411  2456888999999999876655555554  688889888875422111111       


Q NP_000290.2     398 VDPEVFFNATGCL-RKRL--GMRELLALVPQRATSSRVNLSSADAGRQTMRN--YSGLIDSLMAYVQNCVAASRCDDKSV  472 (747)
Q Consensus       398 ~~~~~~~~~~~~~-~~~~--~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~~~~~~  472 (747)
                      +  ..+-|-+... ++.+  .|.+|..+..+..... ..+...+.-....+.  -.|.+..|.+.+..      -+....
T Consensus       593 ~--~~l~nl~~~~~~~~~~~e~~~l~~~a~~~~~~~-~~~d~~~~v~~r~~~l~~~g~~~~Lv~ll~~------~s~~~r  663 (961)
T 4I2W_A          593 A--TIYANLSNAFEKPKVDEEMVKLAQFAKHHVPET-HPKDTEEYVEKRVRALVEEGAVPACVAVSKT------ESKNAL  663 (961)
T ss_dssp             H--HHHHHTTTCCCCCC----------CCCCCSTTC-TTTTSSTTHHHHHHHHHHSSSSHHHHHTTCC------CCSHHH
T ss_pred             H--HHHHHHhcCCCCCCCCHHHHHHHHHHhcCCCCC-CcCCCHHHHHHHHHHHHHCCCHHHHHHHhcC------CCHHHH
Confidence            0  0111111110 0000  0122222211111110 011111111111111  12444444444332      122334


Q NP_000290.2     473 ENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAY---T-E------KSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGW  542 (747)
Q Consensus       473 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~---~-~------~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~  542 (747)
                      +.+..+|++++-.-  +.  |-.-.+..+-..-   . +      .....+..+-..     .-+..+.+...       
T Consensus       664 ~~~~~~l~~l~~~~--~~--R~~ivq~g~~~~Ll~ll~~~~~~~~~~Aa~ALa~l~~-----~~~p~~~~~~~-------  727 (961)
T 4I2W_A          664 ELIARSLLAFAEYE--DL--RGRIIAEGGTVLCLRLTKEASGEGKIKAGHAIAKLGA-----KADPMISFPGQ-------  727 (961)
T ss_dssp             HHHHHHHHTTSSSS--TT--TTTTTTSSHHHHHHHHHHHSTTHHHHHHHHHHHTTSS-----SSCGGGTSTTT-------
T ss_pred             HHHHHHHHHHhCCH--HH--HHHHHHCchHHHHHHHHhcCChHHHHHHHHHHHHHHc-----cCChhhhcCCc-------
Confidence            55566777776211  11  1000001100000   0 0      000000000000     00000111111       


Q NP_000290.2     543 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLSN  621 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-s~d~eVr~~AL~aLsn  621 (747)
                       ...++++.|+.+|..+.+...+..++.+|.+|+..++.     ....+.+.++++.|..+|. +.++.++..|+.++.+
T Consensus       728 -~~~~~i~pLv~lL~~~~~~~~~~eal~ALtnLa~~~~~-----~~~~I~~~~~~~~l~~lL~~~~~~~vr~aA~ell~n  801 (961)
T 4I2W_A          728 -RAYEVVKPLCDLLHPDVEGKANYDSLLTLTNLASVSDS-----IRGRILKEKAIPKIEEFWFMTDHEHLRAAAAELLLN  801 (961)
T ss_dssp             -HHHHTTSGGGTSSSCCSSCTTTTTTHHHHHHHSSSCHH-----HHHHHHHTTCHHHHTTSSSCSTTHHHHHHHHHHHHT
T ss_pred             -chhhHHHHHHHHhCCCCChHHHHHHHHHHHHHHcCCHH-----HHHHHHhcChHHHHHHHHhcCCCHHHHHHHHHHHHH
Confidence             11267899999987334556778899999999986533     3445556788899998888 7788999999999999


Q NP_000290.2     622 MSRHPLL-HRVM--GNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSS--SMLNNIINLCRSSA  696 (747)
Q Consensus       622 La~~~e~-~~ll--~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~--giL~~Ll~LL~s~~  696 (747)
                      |+.++.. ..+.  ..+.+..++.++.+.     .++.++..|+.+|+.++. .+.....+++.  +.+..|..++.+. 
T Consensus       802 L~~~~~~~~~~~~~~~~~~~ll~~l~~~~-----~d~~~~~aA~~aLa~l~~-~~~~~~~i~~~~~~~~~~l~~ll~~~-  874 (961)
T 4I2W_A          802 LLFFEKFYEETVAPGTDRLKLWVLYSAEV-----EEERLSRASAAGFAILTE-DENACARIMDEIKSWPEVFKDIAMHE-  874 (961)
T ss_dssp             TSSSSSSSTTTSSSCSSCHHHHHHHHHCC-----SSSTHHHHHHHHHHHHHS-SHHHHHHTGGGCTTHHHHHHHHHHCS-
T ss_pred             HHcCHHHHHhhCCCCCccchhhhHHhccC-----CCHHHHHHHHHHHHHHhC-CHHHHHHHHHHHhchHHHHHHHhhCC-
Confidence            9976544 2221  223444444443331     357888999999999884 45555555553  3466677777666 


Q NP_000290.2     697 SPKAAEAARLLLSDMWS-SKELQGVLRQQGF  726 (747)
Q Consensus       697 d~eVr~aAL~aLsnL~~-~~~~~~~~~~~~~  726 (747)
                      ++.++..++.+|.+++. +.+....+.+.|.
T Consensus       875 ~~~l~~ra~~~l~nl~~~~~~~~~~~~~~g~  905 (961)
T 4I2W_A          875 DAETQRRGLMGIANIMHSSNKLCSEIVSSEV  905 (961)
T ss_dssp             STTHHHHHHHHTHHHHSSCSHHHHCCSSHHH
T ss_pred             CHHHHHHHHHHHHHHHhcCHHHHHHHHhccH
Confidence            78899999999999965 4444443444443


No 97
>3TT9_A Plakophilin-2; CELL ADHESION; HET: GOL; 1.55A {Homo sapiens}
Probab=97.42  E-value=9.1e-08  Score=88.50  Aligned_cols=221  Identities=45%  Similarity=0.773  Sum_probs=134.5  Template_Neff=12.300

Q NP_000290.2     245 LTIPKAVQYLSSQD--EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd--~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      ..++.++..+...+  ..++..++.++.+++.........+...++++.+..++...+..++..++.+|.+++.......
T Consensus         8 ~~i~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~   87 (233)
T 3TT9_A            8 MTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVFEDNDNK   87 (233)
T ss_dssp             CCHHHHHHTCCSSCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHTTHHHHHHHGGGCCCHHHHHHHHHHHHHHHTTCHHHH
T ss_pred             hHHHHHHHHHhhcCCCHHHHHHHHHHHHHHHccCHHHHHHHHHcchHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCCcHH
Confidence            34556666666544  6788888899988876444444445555678888888877777888999999999886444444


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPE  401 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~  401 (747)
                      ..+...+.++.++.++....+..++..++.++.+++........+.. +++..+..++.... .+-.....+.....+++
T Consensus        88 ~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~ll~~~~-~~~~~~~~~~~~~~~~~  166 (233)
T 3TT9_A           88 LEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIIIPFS-GWPEGDYPKANGLLDFD  166 (233)
T ss_dssp             HHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHHTSGGGHHHHHHHHHHHHCCCCCHHHH-CCCGGGCCCCCTTCCHH
T ss_pred             HHHHHcccHHHHHHHHhhCCCHHHHHHHHHHHHHHccCHHHHHHhhhhcHHHHHHHHHhhcc-CCCCCCCCcccCCCcHH
Confidence            44445567777887775234567888999999999875544444444 66666666665432 11111222222334566


Q NP_000290.2     402 VFFNATGCLRKRLGMRELLALVPQRATSSRVNLSS-ADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH  480 (747)
Q Consensus       402 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  480 (747)
                      +...+.++|..                     +.. .+..++.+....++++.|...++....-...+.+-.+++..+|.
T Consensus       167 ~~~~a~~~l~~---------------------l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~L~  225 (233)
T 3TT9_A          167 IFYNVTGCLRN---------------------MSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILH  225 (233)
T ss_dssp             HHHHHHHHHHH---------------------HTTSCHHHHHHHHTSTTHHHHHHHHHHHHHHTTCTTCHHHHHHHHHHH
T ss_pred             HHHHHHHHHHH---------------------HHhcCHHHHHHHHHcccHHHHHHHHHHcccccCCCChHHHHHHHHHHH
Confidence            65555555432                     111 22334444444455666666554421101115567788999999


Q NP_000290.2     481 NLSYRLD  487 (747)
Q Consensus       481 ~~~~~~~  487 (747)
                      ||+++.+
T Consensus       226 ~l~~~~~  232 (233)
T 3TT9_A          226 NLSYQLE  232 (233)
T ss_dssp             HHCCCCC
T ss_pred             Hhhhccc
Confidence            9987654


No 98
>2Z6H_A Catenin beta-1; Beta-Catenin, C-terminal Domain, Activator, Cell; 2.2A {Homo sapiens}
Probab=97.42  E-value=9.4e-08  Score=103.88  Aligned_cols=378  Identities=17%  Similarity=0.155  Sum_probs=229.8  Template_Neff=11.700

Q NP_000290.2     241 ECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRST  319 (747)
Q Consensus       241 ~~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~  319 (747)
                      +....+++.+...+.+.++.++..++.++..+..............+++..+...+. ..+..++..++.+|..++....
T Consensus        10 ~~~~~~i~~L~~~l~~~~~~vr~~a~~~L~~l~~~~~~~~~~~~~~~~i~~L~~~l~~~~~~~v~~~a~~~L~~l~~~~~   89 (644)
T 2Z6H_A           10 ELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHRE   89 (644)
T ss_pred             HHhCCHHHHHHHHcCCCCHHHHHHHHHHHHHHhCCcHHHHHHHhCCChHHHHHHHHcCCCCHHHHHHHHHHHHHHhCCHH
Confidence            344566777888888778889999999999887653222111111346666777666 4566788888888888865432


Q NP_000290.2     320 TNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK-EELIA-DALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       320 ~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~-~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                       ....+...+.++.+...+. ..++.++..++.++..++...... ..+.. ++++.|+.++...               
T Consensus        90 -~~~~~~~~~~i~~L~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~L~~~l~~~---------------  152 (644)
T 2Z6H_A           90 -GLLAIFKSGGIPALVKMLG-SPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKT---------------  152 (644)
T ss_pred             -HHHHHHHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHhcCC---------------
Confidence             2223333467777888876 556788889999999988653322 22222 6677777766531               


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                       ++++...+..+|..-....                    ...+..... .++++.|...+...     .+.+....++.
T Consensus       153 -~~~~~~~a~~~L~~l~~~~--------------------~~~~~~~~~-~~~~~~L~~~l~~~-----~~~~~~~~a~~  205 (644)
T 2Z6H_A          153 -NVKFLAITTDCLQILAYGN--------------------QESKLIILA-SGGPQALVNIMRTY-----TYEKLLWTTSR  205 (644)
T ss_pred             -CHHHHHHHHHHHHHHhcCC--------------------HHHHHHHHH-CCcHHHHHHHhcCC-----CCHHHHHHHHH
Confidence             3344444444443211000                    000111111 23444444444321     12222233333


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      +|.+++..-                                                   .....+.+.++++.|+.++.
T Consensus       206 ~L~~l~~~~---------------------------------------------------~~~~~~~~~~~l~~l~~~l~  234 (644)
T 2Z6H_A          206 VLKVLSVCS---------------------------------------------------SNKPAIVEAGGMQALGLHLT  234 (644)
T ss_pred             HHHHHccCh---------------------------------------------------HHHHHHHHCCHHHHHHHHhc
Confidence            333332110                                                   00012345667888888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQ  635 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~g  635 (747)
                       ..+..++..++++|.+++.....      ...  ..++++.|+.++.+.+..++..++.+|.+++.. ... ..+...+
T Consensus       235 -~~~~~~~~~a~~~L~~l~~~~~~------~~~--~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~  305 (644)
T 2Z6H_A          235 -DPSQRLVQNCLWTLRNLSDAATK------QEG--MEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVG  305 (644)
T ss_pred             -CCCHHHHHHHHHHHHHHhcCCCC------HHH--HCchHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCHHHHHHHHhCC
Confidence             46778888999999999875321      111  256788888888888888999999999999865 222 2334556


Q NP_000290.2     636 VFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL---AKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMW  712 (747)
Q Consensus       636 iI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~---~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~  712 (747)
                      +++.++..+...    ..+..++..++.+|.+++...+..   ...+...++++.|+.++....+..++..++.+|.+++
T Consensus       306 ~l~~L~~~l~~~----~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~~~a~~~L~~l~  381 (644)
T 2Z6H_A          306 GIEALVRTVLRA----GDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLA  381 (644)
T ss_pred             HHHHHHHHHhcC----CCCHHHHHHHHHHHHHHHcCCCCHHHHHHHHHHCCcHHHHHHHhcCCCCHHHHHHHHHHHHHHh
Confidence            777777776521    035678889999999998753322   2333344677888888875435678899999999999


Q NP_000290.2     713 SSKELQGVLRQQGF  726 (747)
Q Consensus       713 ~~~~~~~~~~~~~~  726 (747)
                      ...+.+..+.+.|.
T Consensus       382 ~~~~~~~~l~~~~~  395 (644)
T 2Z6H_A          382 LCPANHAPLREQGA  395 (644)
T ss_pred             cCHHHHHHHHHCCc
Confidence            87776655555443


No 99
>4U2X_E eVP24, KPNA5C; eVP24, importin alpha6, immune antagonist; 3.153A {Zaire ebolavirus}
Probab=97.42  E-value=9.4e-08  Score=83.77  Aligned_cols=116  Identities=17%  Similarity=0.149  Sum_probs=80.4  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFR-STTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~-~~~~~~~  324 (747)
                      +++.+..++.+.++.++..++.++.++....+.....+...++++.+...+.+.+..++..++.++.+++.. .......
T Consensus         9 ~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~   88 (175)
T 4U2X_E            9 ALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRY   88 (175)
T ss_dssp             SSHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHH
T ss_pred             hHHHHHHHHhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHhCChHHHHHHHHHhcCHHHHHHHHHHHHHHcCCCCHHHHHH
Confidence            455566666667788889999999998865443333444456777888887777778888899999988753 2222223


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~  362 (747)
                      +...+.++.+...+. ..++.++..++.++.+++....
T Consensus        89 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~  125 (175)
T 4U2X_E           89 LVALGCIKPLCDLLT-VMDSKIVQVALNGLENILRLGE  125 (175)
T ss_dssp             HHHHTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHHHhhcH
Confidence            333456777777776 5567788888899888887543


No 100
>4RV1_D Engineered Protein OR497; STRUCTURAL GENOMICS, PSI-BIOLOGY, PROTEIN STRUCTURE; 2.573A {SYNTHETIC CONSTRUCT}
Probab=97.42  E-value=9.1e-08  Score=94.28  Aligned_cols=363  Identities=20%  Similarity=0.249  Sum_probs=217.4  Template_Neff=13.300

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.++.++..++.++..+...........
T Consensus        45 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  124 (420)
T 4RV1_D           45 GVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAI  124 (420)
T ss_dssp             HHHHHHHTTSCSCSSSHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHcCCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHhCCChHHHHHH
Confidence            45556666666777888899999988876543333333334567777777777778888899999988876543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ...++++.+...+. ..++.++..++.++..++..... ...+.. ++++.+..++...                ++++-
T Consensus       125 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~~  187 (420)
T 4RV1_D          125 VDAGGVEVLVKLLT-STDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVKLLTST----------------DSEVQ  187 (420)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCS----------------SHHHH
T ss_pred             HHcCHHHHHHHHHh-CCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCHHHHHHHHhcCC----------------CHHHH
Confidence            33456777777776 55677888899999988864322 222222 5566666655421                23332


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..         +..            ........-.-.++++.+...+++      -+..-...+...|.++.
T Consensus       188 ~~~~~~l~~---------l~~------------~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  240 (420)
T 4RV1_D          188 KEAARALAN---------IAS------------GPTSAIKAIVDAGGVEVLVKLLTS------TDSEVQKEAARALANIA  240 (420)
T ss_dssp             HHHHHHHHH---------HHT------------SCHHHHHHHHTTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHH---------HhC------------CCHHHHHHHHHCCHHHHHHHHhhC------CCHHHHHHHHHHHHHHh
Confidence            222222221         100            000000000001233333322221      01111122222222221


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ...                                                  ......+.+.++++.++..+. +.++.
T Consensus       241 ~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~~  269 (420)
T 4RV1_D          241 SGP--------------------------------------------------DEAIKAIVDAGGVEVLVKLLT-STDSE  269 (420)
T ss_dssp             TSC--------------------------------------------------HHHHHHHHHTTHHHHHHHHTT-CSSHH
T ss_pred             CCC--------------------------------------------------HHHHHHHhhccHHHHHHHHhC-CCCHH
Confidence            100                                                  001111234567777888887 46677


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVFPEVT  641 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI~~Ll  641 (747)
                      ++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++... .. ......++++.+.
T Consensus       270 ~~~~~~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~  344 (420)
T 4RV1_D          270 VQKEAARALANIASGPDE-----AIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLV  344 (420)
T ss_dssp             HHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHH
T ss_pred             HHHHHHHHHHHHHcCCHH-----HHHHHHHCCHHHHHHHHccCCCHHHHHHHHHHHHHHHcChHHHHHHHHHCCHHHHHH
Confidence            888899999998875332     1223344578888888888888889999999999998763 22 2333446777788


Q NP_000290.2     642 RLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       642 ~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      .++.+      .++.++..++.+|.+++...+.....+.+.++++.+..++.+. ++.++..++.+|..+....
T Consensus       345 ~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~~~  411 (420)
T 4RV1_D          345 KLLTS------TDSEVQKEAARALANIASGPTSAIKAIVDAGGVEVLQKLLTST-DSEVQKEAQRALENIKSGG  411 (420)
T ss_dssp             HHTTC------SCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHGGGCS-CHHHHHHHHHHHHHHHHTS
T ss_pred             HHhCC------CCHHHHHHHHHHHHHHHcCChhHHHHHHhccHHHHHHHHcCCC-CHHHHHHHHHHHHhhccCC
Confidence            77776      3678899999999999876444444455556788888888766 7789999999999887644


No 101
>4BQK_A IMPORTIN SUBUNIT ALPHA-1A, T-DNA BORDER; TRANSPORT PROTEIN, HYDROLASE, NUCLEAR LOCALIZATION; HET: PEG; 1.997A {ORYZA SATIVA}
Probab=97.41  E-value=9.4e-08  Score=96.14  Aligned_cols=158  Identities=18%  Similarity=0.251  Sum_probs=116.4  Template_Neff=13.000

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++++.|+.++. +.++.++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.
T Consensus       170 ~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~  243 (456)
T 4BQK_A          170 TRPALPALARLIH-SNDEEVLTDACWALSYLSDGTND-----KIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVT  243 (456)
T ss_dssp             HTTHHHHHHHHTT-CCCHHHHHHHHHHHHHHTSSSHH-----HHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCChH-----HHHHHHHCChHHHHHHHHhCCCHHHHHHHHHHHHHHHc
Confidence            4456777888887 46778888899999998865332     22333456788889999888888899999999999987


Q NP_000290.2     625 HPL-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAE  702 (747)
Q Consensus       625 ~~e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~  702 (747)
                      ... . ..+...++++.+..++...     .++.++..++.+|.+++...+.....+...++++.|..++.+. ++.++.
T Consensus       244 ~~~~~~~~~~~~~~~~~l~~~l~~~-----~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~  317 (456)
T 4BQK_A          244 GDDAQTQCIIDHQALPCLLSLLTQN-----LKKSIKKEACWTISNITAGNKDQIQAVINAGIIGPLVNLLQTA-EFDIKK  317 (456)
T ss_dssp             SCHHHHHHHHTTTHHHHHHHHHHSC-----CCHHHHHHHHHHHHHHHTSCHHHHHHHHHHTCHHHHHHHHHHS-CHHHHH
T ss_pred             CCHHHHHHHHHCChHHHHHHHHHcC-----CCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhhcC-CHHHHH
Confidence            632 2 2334446777888877652     2577889999999999876555555555666788888888766 778888


Q NP_000290.2     703 AARLLLSDMWSS  714 (747)
Q Consensus       703 aAL~aLsnL~~~  714 (747)
                      .++.+|.+++..
T Consensus       318 ~a~~~l~~l~~~  329 (456)
T 4BQK_A          318 EAAWAISNATSG  329 (456)
T ss_dssp             HHHHHHHHHHHH
T ss_pred             HHHHHHHHHHcC
Confidence            999999988863


No 102
>5TBK_C Importin subunit alpha-3, Regulator of; Nuclear Import, Importin alpha, RCC1; 3.45A {Homo sapiens}
Probab=97.41  E-value=1e-07  Score=99.66  Aligned_cols=160  Identities=15%  Similarity=0.207  Sum_probs=115.0  Template_Neff=12.200

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      .+.++++.|+.++....+..++..++.+|.+++.....     ........++++.+..++.+.++.++..++.+|.+++
T Consensus       196 ~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~  270 (521)
T 5TBK_C          196 ISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDP-----PPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLT  270 (521)
T ss_dssp             HHTTCHHHHHTTCCTTSCHHHHHHHHHHHHHHHCCCSS-----CCCHHHHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHH
T ss_pred             HHCCcHHHHHHHhCCCCCHHHHHHHHHHHHHHHcCCCC-----CCCHHHHHHHHHHHHHHhhCCCHHHHHHHHHHHHHHh
Confidence            45567788888886323446778899999998865321     1112223567888888888888889999999999998


Q NP_000290.2     624 RH-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA  701 (747)
Q Consensus       624 ~~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr  701 (747)
                      .. ... ..+...++++.+..++.+      .++.++..++.+|.+++...+.....+...++++.+..++.+. ++.++
T Consensus       271 ~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~  343 (521)
T 5TBK_C          271 DAGNEQIQMVIDSGIVPHLVPLLSH------QEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHP-KEKIN  343 (521)
T ss_dssp             HHCHHHHHHHHHTTCHHHHGGGGGC------SSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCGGGHHHHHTCS-CHHHH
T ss_pred             ccChHHHHHHHHCChHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHhCCHHHhHHHHhhCC-CHHHH
Confidence            76 222 233445677788888765      3677888999999999876444444555557788888888766 78889


Q NP_000290.2     702 EAARLLLSDMWSSK  715 (747)
Q Consensus       702 ~aAL~aLsnL~~~~  715 (747)
                      ..++.+|.+++...
T Consensus       344 ~~a~~~l~~l~~~~  357 (521)
T 5TBK_C          344 KEAVWFLSNITAGN  357 (521)
T ss_dssp             HHHHHHHHHHTTSC
T ss_pred             HHHHHHHHHHhCCC
Confidence            99999999988653


No 103
>5TBK_D Importin subunit alpha-3, Regulator of; Nuclear Import, Importin alpha, RCC1; 3.45A {Homo sapiens}
Probab=97.41  E-value=1e-07  Score=99.66  Aligned_cols=160  Identities=15%  Similarity=0.207  Sum_probs=115.0  Template_Neff=12.200

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      .+.++++.|+.++....+..++..++.+|.+++.....     ........++++.+..++.+.++.++..++.+|.+++
T Consensus       196 ~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~  270 (521)
T 5TBK_D          196 ISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDP-----PPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLT  270 (521)
T ss_dssp             HHTCCHHHHHTTCCTTSCHHHHHHHHHHHHHHHCCCSS-----CCCHHHHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHH
T ss_pred             HHCCcHHHHHHHhCCCCCHHHHHHHHHHHHHHHcCCCC-----CCCHHHHHHHHHHHHHHhhCCCHHHHHHHHHHHHHHh
Confidence            45567788888886323446778899999998865321     1112223567888888888888889999999999998


Q NP_000290.2     624 RH-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA  701 (747)
Q Consensus       624 ~~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr  701 (747)
                      .. ... ..+...++++.+..++.+      .++.++..++.+|.+++...+.....+...++++.+..++.+. ++.++
T Consensus       271 ~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~  343 (521)
T 5TBK_D          271 DAGNEQIQMVIDSGIVPHLVPLLSH------QEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHP-KEKIN  343 (521)
T ss_dssp             HHCHHHHHHHHHTTCHHHHGGGGGC------SSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCGGGHHHHHHCS-CHHHH
T ss_pred             ccChHHHHHHHHCChHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHhCCHHHhHHHHhhCC-CHHHH
Confidence            76 222 233445677788888765      3677888999999999876444444555557788888888766 78889


Q NP_000290.2     702 EAARLLLSDMWSSK  715 (747)
Q Consensus       702 ~aAL~aLsnL~~~~  715 (747)
                      ..++.+|.+++...
T Consensus       344 ~~a~~~l~~l~~~~  357 (521)
T 5TBK_D          344 KEAVWFLSNITAGN  357 (521)
T ss_dssp             HHHHHHHHHHTTSC
T ss_pred             HHHHHHHHHHhCCC
Confidence            99999999988653


No 104
>4U2X_F eVP24, KPNA5C; eVP24, importin alpha6, immune antagonist; 3.153A {Zaire ebolavirus}
Probab=97.37  E-value=1.2e-07  Score=83.04  Aligned_cols=116  Identities=17%  Similarity=0.149  Sum_probs=79.8  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFR-STTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~-~~~~~~~  324 (747)
                      +++.+..++.+.++.++..+++++.++..........+...++++.+..++.+.++.++..++.++..++.. .......
T Consensus         9 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~   88 (175)
T 4U2X_F            9 ALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRY   88 (175)
T ss_dssp             CSHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHH
T ss_pred             hHHHHHHHHhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCChHHHHHHHHHhCCHHHHHHHHHHHHHHhcCCCHHHHHH
Confidence            445566666666778889999999998865443333444446777888877776778888899999988753 2222233


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~  362 (747)
                      +...+.++.+...+. ..++.++..++.++.+++....
T Consensus        89 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~  125 (175)
T 4U2X_F           89 LVALGCIKPLCDLLT-VMDSKIVQVALNGLENILRLGE  125 (175)
T ss_dssp             HHHHTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcch
Confidence            333456777777776 5566788888888888877543


No 105
>4V3Q_A YIII_M4_AII; DE NOVO PROTEIN, PROTEIN ENGINEERING; HET: GOL, CA; 1.8A {SYNTHETIC CONSTRUCT}
Probab=97.37  E-value=1.2e-07  Score=87.00  Aligned_cols=113  Identities=25%  Similarity=0.271  Sum_probs=78.0  Template_Neff=12.900

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETR  326 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll  326 (747)
                      ++.+...+.+.++.++..++.++..++...+.....+...++++.+...+.+.+..++..++.++..++...+.....+.
T Consensus        10 ~~~~~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~   89 (247)
T 4V3Q_A           10 LPQMVQQLNSPDQQELQSALRKLSQIASGGDEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGDEQIQAVI   89 (247)
T ss_dssp             HHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHH
T ss_pred             HHHHHHHhcCCCHHHHHHHHHHHHHHHcCChhhhhhhhccCcHHHHHHHhcCCCHHHHHHHHHHHHHHHcCcHHHHHHHH
Confidence            34455566677788888899999888765444444444556778888888777778888999999988765443333333


Q NP_000290.2     327 RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       327 ~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ..++++.+...+. +.++.++..++.++..++..
T Consensus        90 ~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  122 (247)
T 4V3Q_A           90 DAGALPALVQLLS-SPNEQILQEALWTLGNIASG  122 (247)
T ss_dssp             HTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTS
T ss_pred             HCCcHHHHHHHhc-CCCHHHHHHHHHHHHHHHcC
Confidence            4456777777776 45667777788888777753


No 106
>3NMZ_A APC variant protein, Rho guanine; protein-protein complex, armadillo repeats, CELL; 3.01A {Homo sapiens}
Probab=97.34  E-value=1.5e-07  Score=97.01  Aligned_cols=136  Identities=21%  Similarity=0.259  Sum_probs=84.7  Template_Neff=12.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDE-SAKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~-~~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .+++.+..++...++.++..++.+|.+++.... .....+...++++.+..++. ..+..++..++.++.+++.......
T Consensus       243 ~~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~  322 (458)
T 3NMZ_A          243 GCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENK  322 (458)
T ss_pred             CcHHHHHHHhcCCCHHHHHHHHHHHHHHHCCCChhHHHHHHHCCHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCchhH
Confidence            456667777777777888999999999887543 22334444567777888777 5567788889999999886433333


Q NP_000290.2     323 LETRR-QNGIREAVSLLRR---TGNAEIQKQLTGLLWNLSS----TDELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       323 ~~ll~-~~IL~~Ll~lL~s---s~d~eVr~~AL~aLsnLas----~~~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ..+.. .+.++.+..++..   ..+..++..++.++.+++.    .......+.+ ++++.|+.++.
T Consensus       323 ~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~l~~~~~~~~l~~~l~  389 (458)
T 3NMZ_A          323 ADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLK  389 (458)
T ss_pred             HHHHHhcChHHHHHHHHcCCCCCCCHHHHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhC
Confidence            33333 4566666666641   1234566677777766652    2222222333 56666666654


No 107
>3L6X_A Catenin delta-1, E-cadherin; p120, catenin, cadherin, E-cadherin, armadillo; HET: SO4; 2.4A {Homo sapiens}
Probab=97.34  E-value=1.6e-07  Score=102.08  Aligned_cols=377  Identities=16%  Similarity=0.154  Sum_probs=185.5  Template_Neff=11.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQ-DESAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~-~~~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      +++.|+.++.+.+..++..++.+|.+++.. .......+...+.++.++.++.. .+..++..++.+|.+++.... ...
T Consensus        91 ~i~~Lv~lL~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~i~~L~~ll~~~~~~~v~~~a~~~L~~L~~~~~-~~~  169 (584)
T 3L6X_A           91 GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDS-IKM  169 (584)
T ss_dssp             HHHHHHHGGGCSSHHHHHHHHHHHHHHTSSSCHHHHHHHHHTTHHHHHHHHHHHCCSHHHHHHHHHHHHHHTTSGG-GHH
T ss_pred             cHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCCHHHHHHHHcCChHHHHHHHHHHcCCHHHHHHHHHHHHHHhcCHH-HHH
Confidence            466677777777788999999999999874 34444445556778888888875 366788888999988875432 222


Q NP_000290.2     324 ETRRQNGIREAVSLLR-----------------RTGNAEIQKQLTGLLWNLSSTDE-LKEELIA--DALPVLADRVIIPF  383 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~-----------------ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve--giLe~Lv~LL~~~~  383 (747)
                      .+... .+..+...+.                 ...+..++..++.+|.+++.... ....+..  ++++.|+.+|....
T Consensus       170 ~l~~~-~l~~L~~~l~~~~~~~~~~~~~~~~~~~~~~~~v~~~a~~~L~~l~~~~~~~~~~l~~~~g~v~~L~~~l~~~~  248 (584)
T 3L6X_A          170 EIVDH-ALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEI  248 (584)
T ss_dssp             HHHHH-THHHCCCCCCHHHHCCC----------CCCCHHHHHHHHHHHHHHTSSCHHHHHHHHHSTTHHHHHHHHHHHHH
T ss_pred             HHHHH-HHHHHHHhccccCCCCCCCCCcCCCCcccChHHHHHHHHHHHHHHhcCCHHHHHHHHhCCCHHHHHHHHHHHHh
Confidence            22222 4444444431                 12235677888899998887542 3333333  67788888876432


Q NP_000290.2     384 SGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMR--E------LLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLM  455 (747)
Q Consensus       384 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  455 (747)
                      ..          ...++++.-++..+|+.-..-.  +      .....+.-....+   .....++..+. -.+.++.|.
T Consensus       249 ~~----------~~~~~~~~~~a~~~L~~L~~~~~~~~~~~~~~~~~~~~~~~~~~---~~~~~~~~~l~-~~~~~~~l~  314 (584)
T 3L6X_A          249 GQ----------KDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTG---TSPARGYELLF-QPEVVRIYI  314 (584)
T ss_dssp             HT----------TCCSCHHHHHHHHHHHHHHTTHHHHSTTCCC-----------------CCCCGGGGGG-SHHHHHHHH
T ss_pred             cC----------CCCChHHHHHHHHHHHHHHhhhhccChhHHHHHHhcCcCCCCCC---CCChhhhhHhh-ChhHHHHHH
Confidence            10          0123334444444443211100  0      0000000000000   00111122221 134555555


Q NP_000290.2     456 AYVQNCVAASRCDDKSVENCMCVLHNLSYRLD---AEVPTRYRQLEYNAR----------NAYTEKSSTGCFSNKSDKMM  522 (747)
Q Consensus       456 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~---~~~~~~~~~~~~~~~----------~~~~~~~~~~~~~~~~~~~~  522 (747)
                      ..+...     -+..-.+.+..+|.||+..-.   .++....+  +...-          +.........+..|-+.   
T Consensus       315 ~ll~~~-----~~~~~~~~a~~~L~~L~~~~~~~~~~~~~~~~--~~~~l~~L~~ll~~~~~~v~~~a~~~L~~L~~---  384 (584)
T 3L6X_A          315 SLLKES-----KTPAILEASAGAIQNLCAGRWTYGRYIRSALR--QEKALSAIADLLTNEHERVVKAASGALRNLAV---  384 (584)
T ss_dssp             HHHHHC-----CCHHHHHHHHHHHHHHHSSCSHHHHHHHHHHT--SHHHHHHHHHGGGCSCHHHHHHHHHHHHHHHT---
T ss_pred             HHHHcC-----CCHHHHHHHHHHHHHHhCCCccCCHHHHHHHH--HcChHHHHHHHhcCCCHHHHHHHHHHHHHHhc---
Confidence            554431     144556777888888876321   11111000  00000          00001111111111100   


Q NP_000290.2     523 NNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSK--------KDATLEACAGALQNLTASKGLMSSGMSQLIGLKE  594 (747)
Q Consensus       523 ~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~--------d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~  594 (747)
                                   +...... +..++++.|+.+|.. .        +..++..++.+|.+++.....     ....+.+.
T Consensus       385 -------------~~~~~~~-l~~~~l~~L~~~L~~-~~~~~~~~~~~~~~~~~l~~L~~l~~~~~~-----~~~~l~~~  444 (584)
T 3L6X_A          385 -------------DARNKEL-IGKHAIPNLVKNLPG-GQQNSSWNFSEDTVISILNTINEVIAENLE-----AAKKLRET  444 (584)
T ss_dssp             -------------TCSCHHH-HHHHHHHHHHHTSSS-SSCSGGGTCCHHHHHHHHHHHHHHHTTCHH-----HHHHHHHT
T ss_pred             -------------ChHHHHH-HHcchHHHHHHcCCC-CCCCCCcCCCHHHHHHHHHHHHHHHhcCHH-----HHHHHHHC
Confidence                         0011111 224788888888863 3        334467888888888764332     23444577


Q NP_000290.2     595 KGLPQIARLLQSG--NSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPE-VTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       595 giI~~Ll~LL~s~--d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~-Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      ++++.|+.++...  +..++..|+.+|.+++..... ..+...++++. +..++...    ..++.++..++.+|.++..
T Consensus       445 ~~l~~L~~ll~~~~~~~~v~~~a~~~L~~l~~~~~~~~~l~~~g~~~~~l~~~~~~~----~~~~~~~~~a~~~L~~l~~  520 (584)
T 3L6X_A          445 QGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNA----SRSQSSHSYDDSTLPLIDR  520 (584)
T ss_dssp             THHHHHHHHHTCSSSCHHHHHHHHHHHHHHHTSHHHHHHHHTTTCCGGGGCCC---------------------------
T ss_pred             CHHHHHHHHHhcCCCCHHHHHHHHHHHHHHhCCHHHHHHHHHcCCchhhceeccccc----ccCCCCCCcccccccccCC
Confidence            8999999998753  477899999999999876444 33445566676 55553211    0357788889999999987


Q NP_000290.2     671 SQ  672 (747)
Q Consensus       671 ~s  672 (747)
                      ..
T Consensus       521 ~~  522 (584)
T 3L6X_A          521 NQ  522 (584)
T ss_dssp             --
T ss_pred             CC
Confidence            53


No 108
>5MFI_B YIII(Dq.V2)4CqI, (KR)4; Designed armadillo repeat protein, peptide; 1.45A {synthetic construct}
Probab=97.33  E-value=1.5e-07  Score=85.77  Aligned_cols=113  Identities=20%  Similarity=0.252  Sum_probs=78.4  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..++...+.....+...++++.+...+.+.+..++..++.++.+++.........+
T Consensus         5 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~   84 (243)
T 5MFI_B            5 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKL   84 (243)
T ss_dssp             CHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHTTTSSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             cHHHHHHHHcCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666777888899999998876544443444445677888888877778888899999998886444333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      ...++++.+...+. ..++.++..++.++..++.
T Consensus        85 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~  117 (243)
T 5MFI_B           85 IEAGALSPLVKLLD-DASEEVIQEAVWAIANIAS  117 (243)
T ss_dssp             HHTTCHHHHHHHTS-SSCHHHHHHHHHHHHHHTT
T ss_pred             HHcCcHHHHHHHHh-cCCHHHHHHHHHHHHHHHc
Confidence            33456777777775 4566677777888877775


No 109
>5MFJ_B YIII(Dq.V2)4CqI, (KR)5; Designed armadillo repeat protein, peptide; 1.53A {synthetic construct}
Probab=97.33  E-value=1.5e-07  Score=85.77  Aligned_cols=113  Identities=20%  Similarity=0.252  Sum_probs=77.5  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..++...+.....+...++++.+...+.+.+..++..++.++.+++.........+
T Consensus         5 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~   84 (243)
T 5MFJ_B            5 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKL   84 (243)
T ss_dssp             CHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHGGGCSCTTTC-CHHHHHHHHTTSCHHHHHHH
T ss_pred             cHHHHHHHHcCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666777888899999998876544443444445677888888877778888899999998886444333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      ...++++.+...+. ..++.++..++.++..++.
T Consensus        85 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~  117 (243)
T 5MFJ_B           85 IEAGALSPLVKLLD-DASEEVIQEAVWAIANIAS  117 (243)
T ss_dssp             HHTTCHHHHHHHHH-HSCHHHHHHHHHHHHHHHT
T ss_pred             HHcCcHHHHHHHHh-cCCHHHHHHHHHHHHHHHc
Confidence            33456777777775 4566677777888877775


No 110
>5VOZ_P V-type proton ATPase catalytic subunit; V-ATPase, SidK, rotational state 3;{Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=97.30  E-value=2.1e-07  Score=101.03  Aligned_cols=134  Identities=14%  Similarity=0.103  Sum_probs=89.5  Template_Neff=8.900

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICK--LVDLLRS-PNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~--Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .++.++.++.+ +..++..++.+|..++... .........+.++.  ++.++.. .+..++..++.+|..++... ...
T Consensus       124 ~~~~li~lL~~-d~~i~~~a~~~L~~L~~~~-~~~~~~~~~~~l~~~~li~~L~~~~~~~~~~~a~~~L~~L~~~~-~~r  200 (478)
T 5VOZ_P          124 LEQLFDVSLKG-DFQTVLISGFNVVSLLVQN-GLHNVKLVEKLLKNNNLINILQNIEQMDTCYVCIRLLQELAVIP-EYR  200 (478)
T ss_dssp             HHHHTTSTTSS-CHHHHHHHHHHHHHHHTSS-SCCCHHHHHHHHSSHHHHHHHHCSSCHHHHHHHHHHHHHHTTSH-HHH
T ss_pred             HHHHHHHHcCC-CHHHHHHHHHHHHHHHHhc-cccCcccchhhcccchHHHHHhccCCccHHHHHHHHHHHHcCCh-HHH
Confidence            45666667766 6677888888888887643 22112223456666  7777753 35667888899999888643 333


Q NP_000290.2     323 LETRR--QNGIREAVSLLRRT----------------GNAEIQKQLTGLLWNLSSTDELKEELIA---DALPVLADRVII  381 (747)
Q Consensus       323 ~~ll~--~~IL~~Ll~lL~ss----------------~d~eVr~~AL~aLsnLas~~~~~~~Lve---giLe~Lv~LL~~  381 (747)
                      ..+..  .+.++.|+.++...                .++.++..++.++..|+........+..   ++++.|+++++.
T Consensus       201 ~~~~~~~~g~i~~Lv~lL~~~~~~~~~~~~~~~~~~~~~~ql~~~a~~~L~~Ls~~~~~~~~l~~~~~~~i~~Lv~ll~~  280 (478)
T 5VOZ_P          201 DVIWLHEKKFMPTLFKILQRATDSQLATRIVATNSNHLGIQLQYHSLLLIWLLTFNPVFANELVQKYLSDFLDLLKLVKI  280 (478)
T ss_dssp             HHHHHSTTSSHHHHHHHHHHHHHSCSSCCCTTTSSSHHHHHHHHHHHHHHHHHTTSHHHHHHHHHHSHHHHGGGHHHHHH
T ss_pred             HHHHHccccchHHHHHHHHhccccccccccccccCcCcCHHHHHHHHHHHHHHhcCHHHHHHHHHHhHHHHHHHHHHHhc
Confidence            33444  35777888877621                2567888899999999876555555543   688889998886


Q NP_000290.2     382 P  382 (747)
Q Consensus       382 ~  382 (747)
                      .
T Consensus       281 ~  281 (478)
T 5VOZ_P          281 T  281 (478)
T ss_dssp             C
T ss_pred             c
Confidence            4


No 111
>5D80_H V-type proton ATPase catalytic subunit; Hydrolase, Autoinhibition; 6.202A {Saccharomyces cerevisiae}
Probab=97.30  E-value=2.1e-07  Score=101.03  Aligned_cols=134  Identities=14%  Similarity=0.103  Sum_probs=89.5  Template_Neff=8.900

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICK--LVDLLRS-PNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~--Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .++.++.++.+ +..++..++.+|..++... .........+.++.  ++.++.. .+..++..++.+|..++... ...
T Consensus       124 ~~~~li~lL~~-d~~i~~~a~~~L~~L~~~~-~~~~~~~~~~~l~~~~li~~L~~~~~~~~~~~a~~~L~~L~~~~-~~r  200 (478)
T 5D80_H          124 LEQLFDVSLKG-DFQTVLISGFNVVSLLVQN-GLHNVKLVEKLLKNNNLINILQNIEQMDTCYVCIRLLQELAVIP-EYR  200 (478)
T ss_pred             HHHHHHHHcCC-CHHHHHHHHHHHHHHHHhc-cccCcccchhhcccchHHHHHhccCCccHHHHHHHHHHHHcCCh-HHH
Confidence            45666667766 6677888888888887643 22112223456666  7777753 35667888899999888643 333


Q NP_000290.2     323 LETRR--QNGIREAVSLLRRT----------------GNAEIQKQLTGLLWNLSSTDELKEELIA---DALPVLADRVII  381 (747)
Q Consensus       323 ~~ll~--~~IL~~Ll~lL~ss----------------~d~eVr~~AL~aLsnLas~~~~~~~Lve---giLe~Lv~LL~~  381 (747)
                      ..+..  .+.++.|+.++...                .++.++..++.++..|+........+..   ++++.|+++++.
T Consensus       201 ~~~~~~~~g~i~~Lv~lL~~~~~~~~~~~~~~~~~~~~~~ql~~~a~~~L~~Ls~~~~~~~~l~~~~~~~i~~Lv~ll~~  280 (478)
T 5D80_H          201 DVIWLHEKKFMPTLFKILQRATDSQLATRIVATNSNHLGIQLQYHSLLLIWLLTFNPVFANELVQKYLSDFLDLLKLVKI  280 (478)
T ss_pred             HHHHHccccchHHHHHHHHhccccccccccccccCcCcCHHHHHHHHHHHHHHhcCHHHHHHHHHHhHHHHHHHHHHHhc
Confidence            33444  35777888877621                2567888899999999876555555543   688889998886


Q NP_000290.2     382 P  382 (747)
Q Consensus       382 ~  382 (747)
                      .
T Consensus       281 ~  281 (478)
T 5D80_H          281 T  281 (478)
T ss_pred             c
Confidence            4


No 112
>1JDH_A BETA-CATENIN, hTcf-4; BETA-CATENIN, TCF4, PROTEIN-PROTEIN COMPLEX, TRANSCRIPTION; 1.9A {Homo sapiens} SCOP: a.118.1.1
Probab=97.29  E-value=1.9e-07  Score=95.60  Aligned_cols=138  Identities=25%  Similarity=0.275  Sum_probs=87.6  Template_Neff=13.100

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLR--SPNQNVQQAAAGALRNLVFRSTTN-  321 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~--s~d~eVr~~AL~aLs~La~~~~~~-  321 (747)
                      .+++.+...+.+.+..++..++.++..++.........+...+.++.+...+.  ..++.++..++.++..++...... 
T Consensus       266 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~~~~  345 (529)
T 1JDH_A          266 GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAE  345 (529)
T ss_dssp             HHHHHHHHHTTCSCHHHHHHHHHHHHHHTTTCHHHHHHHHHTTHHHHHHHHHHHHTTCHHHHHHHHHHHHHHTSSSTTHH
T ss_pred             hHHHHHHHHhCCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHcCHHHHHHHHHHhcCCChHhHHHHHHHHHHHhcCcccHH
Confidence            44555666666667778888888888887654433333344556666766554  345677888888888887654321 


Q NP_000290.2     322 --KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIP  382 (747)
Q Consensus       322 --~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~  382 (747)
                        .......+.++.+...+....++.++..++.++.+++........+.. ++++.|..++...
T Consensus       346 ~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~  409 (529)
T 1JDH_A          346 MAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRA  409 (529)
T ss_dssp             HHHHHHHHTTCHHHHHHTTSTTCCHHHHHHHHHHHHHHTTSGGGHHHHHHTTHHHHHHHHHHHH
T ss_pred             HHHHHHHhcccHHHHHHHHCCCCCHHHHHHHHHHHHHHhcChhhhHHHHhcCHHHHHHHHHHhc
Confidence              112222356667777775223567888899999988876444444444 6777777777643


No 113
>2Z6G_A B-catenin; Full-Length, Beta-Catenin, CELL ADHESION; 3.4A {Danio rerio}
Probab=97.28  E-value=2.2e-07  Score=105.08  Aligned_cols=353  Identities=20%  Similarity=0.229  Sum_probs=182.2  Template_Neff=10.700

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP-NQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~-d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .+++.+..++.+.+..++..++.+|..++.........+...+++..++.++... +..++..++.+|..+..... ...
T Consensus       276 ~~~~~L~~lL~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~L~~~l~~~~~~~v~~~a~~~L~~l~~~~~-~~~  354 (780)
T 2Z6G_A          276 GGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSS-NKP  354 (780)
T ss_pred             CHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHhCCCCCHHHHHHHHHHHHHHhCCHH-HHH
Confidence            3455566666666778888888888888764443333333445677777777654 56777888888888775432 222


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      .+...++++.+...+. ..+..++..++.+|..++...... ....++++.|+.++...                ++++.
T Consensus       355 ~~~~~~~l~~L~~~l~-~~~~~v~~~al~~L~~l~~~~~~~-~~~~~~l~~L~~~l~~~----------------~~~v~  416 (780)
T 2Z6G_A          355 AIVEAGGMQALGLHLT-DPSQRLVQNCLWTLRNLSDAATKQ-EGMEGLLGTLVQLLGSD----------------DINVV  416 (780)
T ss_pred             HHHHCCHHHHHHHHcc-CCCHHHHHHHHHHHHHHhcCCCCH-HHHcChHHHHHHHhcCC----------------CHHHH
Confidence            2333456777777776 556778888999998887643321 11125566666666421                23344


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..+|..-..-      .+.              .+. .-.-.+.++.|...+..    ..-+..-.+.+.+.|.++.
T Consensus       417 ~~a~~~L~~l~~~------~~~--------------~~~-~~~~~~~l~~L~~~l~~----~~~~~~v~~~a~~~L~~l~  471 (780)
T 2Z6G_A          417 TCAAGILSNLTCN------NYK--------------NKM-MVCQVGGIEALVRTVLR----AGDREDITEPAICALRHLT  471 (780)
T ss_pred             HHHHHHHHHHHcC------CHH--------------HHH-HHHHCChHHHHHHHHhc----CCCCHHHHHHHHHHHHHHH
Confidence            4444443221100      000              000 00012233333322211    0112233456666666666


Q NP_000290.2     484 YRLDAEV------------PTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRT  551 (747)
Q Consensus       484 ~~~~~~~------------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~  551 (747)
                      .+.....            +.-.+-+.. ..+....+....++.+-..                .......+.+.++++.
T Consensus       472 ~~~~~~~~~~~~~~~~~~i~~L~~ll~~-~~~~~v~~~a~~~L~~l~~----------------~~~~~~~~~~~~~l~~  534 (780)
T 2Z6G_A          472 SRHQDAEMAQNAVRLHYGLPVVVKLLHP-PSHWPLIKATVGLIRNLAL----------------CPANHAPLREQGAIPR  534 (780)
T ss_pred             cCCccHHHHHHHHHHCCcHHHHHHHhcC-CCCHHHHHHHHHHHHHHhc----------------CHHHHHHHHhCChHHH
Confidence            5442110            000000000 0000000011111111100                0011112345566666


Q NP_000290.2     552 YLNLMGKSKK----------------------DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS  609 (747)
Q Consensus       552 LL~LL~ss~d----------------------~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~  609 (747)
                      |+.++.. ..                      ..++..++.+|.+++....      ....+...++++.|+.++.+.++
T Consensus       535 L~~ll~~-~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~a~~aL~~L~~~~~------~~~~~~~~~~l~~L~~~l~~~~~  607 (780)
T 2Z6G_A          535 LVQLLVR-AHQDTQRRTSMGGTQQQFVEGVRMEEIVEACTGALHILARDIH------NRIVIRGLNTIPLFVQLLYSPIE  607 (780)
T ss_pred             HHHHhcC-CCHHHHHHHHhhhhhhhhhcCCChHHHHHHHHHHHHHHhCChh------HHHHHHhCCcHHHHHHHhcCCCH
Confidence            7666652 22                      2366777777777775422      12222345667777777777677


Q NP_000290.2     610 DVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       610 eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                      .++..++.+|.+++..... ..+...++++.|..++.+      .++.++..++.+|.+|+..
T Consensus       608 ~v~~~a~~~L~~l~~~~~~~~~~~~~~~i~~L~~ll~~------~~~~v~~~a~~~L~~L~~~  664 (780)
T 2Z6G_A          608 NIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHS------RNEGVATYAAAVLFRMSED  664 (780)
T ss_pred             HHHHHHHHHHHHHhcCHHHHHHHHHCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHHCC
Confidence            7788888888888755332 233345566777777665      3567777788888887764


No 114
>1HO8_A VACUOLAR ATP SYNTHASE SUBUNIT H; HEAT repeat, HYDROLASE; 2.95A {Saccharomyces cerevisiae} SCOP: a.118.1.9
Probab=97.27  E-value=2.5e-07  Score=100.53  Aligned_cols=135  Identities=14%  Similarity=0.099  Sum_probs=89.8  Template_Neff=8.900

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICK--LVDLLRS-PNQNVQQAAAGALRNLVFRSTTN  321 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~--Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~  321 (747)
                      ..++.++.++.+ +..++..++.+|..++... .........+.++.  ++.++.. .+..++..++.+|..++... ..
T Consensus       125 ~~~~~li~lL~~-d~~i~~~a~~~L~~L~~~~-~~~~~~~~~~~l~~~~lv~~L~~~~~~~~~~~a~~~L~~L~~~~-~~  201 (480)
T 1HO8_A          125 QLEQLFDVSLKG-DFQTVLISGFNVVSLLVQN-GLHNVKLVEKLLKNNNLINILQNIEQMDTCYVCIRLLQELAVIP-EY  201 (480)
T ss_dssp             HHHHHHHHCSCS-SHHHHHHHHHHHHHHHTST-TTCCHHHHHHHHHCHHHHHHHHCTTCHHHHHHHHHHHHHHHTSH-HH
T ss_pred             hHHHHHHHHcCC-CHHHHHHHHHHHHHHHHhc-cccCcccchhhcccchHHHHHhcccCccHHHHHHHHHHHHcCCh-HH
Confidence            345666777766 6677888888888887643 22112223456776  7777753 35667888899998888643 33


Q NP_000290.2     322 KLETRR--QNGIREAVSLLRRT----------------GNAEIQKQLTGLLWNLSSTDELKEELIA---DALPVLADRVI  380 (747)
Q Consensus       322 ~~~ll~--~~IL~~Ll~lL~ss----------------~d~eVr~~AL~aLsnLas~~~~~~~Lve---giLe~Lv~LL~  380 (747)
                      ...+..  .+.++.|+.++...                .++.++..++.++..|.........+..   ++++.|+++++
T Consensus       202 r~~~~~~~~~~i~~Lv~lL~~~~~~~~~~~~~~~~~~~~~~ql~~~a~~~L~~Ls~~~~~~~~i~~~~~~~i~~Lv~ll~  281 (480)
T 1HO8_A          202 RDVIWLHEKKFMPTLFKILQRATDSQLATRIVATNSNHLGIQLQYHSLLLIWLLTFNPVFANELVQKYLSDFLDLLKLVK  281 (480)
T ss_dssp             HHHHHTTHHHHHHHHHHHHHHHHC-------------CCHHHHHHHHHHHHHHHTTSHHHHHHHHTTSHHHHHHHHHHHH
T ss_pred             HHHHHHccccchHHHHHHHHhccccchhcchhhccCcCCCHHHHHHHHHHHHHHhcCHHHHHHHHHHhHHHHHHHHHHHh
Confidence            333444  35677787777621                2567888899999998876555555543   68888999888


Q NP_000290.2     381 IP  382 (747)
Q Consensus       381 ~~  382 (747)
                      ..
T Consensus       282 ~~  283 (480)
T 1HO8_A          282 IT  283 (480)
T ss_dssp             HC
T ss_pred             hc
Confidence            64


No 115
>6S9O_F designed Armadillo repeat protein with; peptide binder, repeat protein, designed; HET: CA, EDO; 3.17A {synthetic construct}
Probab=97.21  E-value=2.9e-07  Score=88.31  Aligned_cols=135  Identities=25%  Similarity=0.275  Sum_probs=88.9  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++..+..........+...++++.+...+...++.++..++.++..++..........
T Consensus       173 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  252 (344)
T 6S9O_F          173 ALPALVQLLSSPNEQILQLALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV  252 (344)
T ss_dssp             CHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHHcCChHHHHHHHhcChHHHHHHHccCCCHHHHHHHHHHHHHHHcCcHHHHHHH
Confidence            45556666666677888889999988876543333333334567777777777777888889999988875544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVII  381 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~~  381 (747)
                      ...++++.+...+. ..++.++..++.++..++..... ...+.. ++++.|..++..
T Consensus       253 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~  309 (344)
T 6S9O_F          253 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSH  309 (344)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGC
T ss_pred             HHCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCHHHHHHHHhhC
Confidence            34456777777776 55677888899999988865322 222222 566666666643


No 116
>1XM9_A plakophilin 1  Plakophilin-1; armadillo repeat, CELL ADHESION; 2.8A {Homo sapiens} SCOP: a.118.1.24
Probab=97.20  E-value=3.2e-07  Score=93.10  Aligned_cols=114  Identities=15%  Similarity=0.165  Sum_probs=77.3  Template_Neff=12.600

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP------NQNVQQAAAGALRNLVFRST  319 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~------d~eVr~~AL~aLs~La~~~~  319 (747)
                      +++.+..++.+.++.++..++.+|.+++... .....+ ...+++.+..++...      +..++..++.++.+++...+
T Consensus       332 ~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~-~~~~~~-~~~~~~~l~~~l~~~~~~~~~~~~~~~~a~~~L~~l~~~~~  409 (457)
T 1XM9_A          332 GLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LLHRVM-GNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP  409 (457)
T ss_dssp             CHHHHHHHTTCSCHHHHHHHHHHHHHHHTSG-GGHHHH-HHHTHHHHHHTTTSCCSCSTTHHHHHHHHHHHHHHHHTTCT
T ss_pred             hHHHHHHHHhcCCHHHHHHHHHHHHHHhcCH-HHHHHH-HcccHHHHHHHHhcCCCCCCCCHHHHHHHHHHHHHHHhcCH
Confidence            4556666676677788889999999988542 222222 234667777777655      57788888999988875444


Q NP_000290.2     320 TNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD  361 (747)
Q Consensus       320 ~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~  361 (747)
                      .....+...+.++.+..++....++.++..++.++..++...
T Consensus       410 ~~~~~~~~~~~~~~l~~ll~~~~~~~v~~~a~~~L~~l~~~~  451 (457)
T 1XM9_A          410 QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  451 (457)
T ss_dssp             HHHHHHCCHHHHHHHHHHHHCTTCHHHHHHHHHHHHTTSSST
T ss_pred             HHHHHHHhccHHHHHHHHHhCCCCHHHHHHHHHHHHHHhhcH
Confidence            444444455677778887762256778888888888887644


No 117
>1XQS_B HSPBP1 protein, Heat shock 70; armadillo repeat, superhelical twist, CHAPERONE; HET: AMP; 2.9A {Homo sapiens} SCOP: a.118.1.21
Probab=97.20  E-value=3.3e-07  Score=87.92  Aligned_cols=134  Identities=22%  Similarity=0.180  Sum_probs=90.6  Template_Neff=11.900

Q NP_000290.2     246 TIPKAVQ-YLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP-NQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~-lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~-d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      +++.++. ++.+.+..++..++.++.+++.........+...++++.+..++... +..++..++.++.+++........
T Consensus        66 ~i~~l~~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~  145 (280)
T 1XQS_B           66 GMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVAAIQEQVLGLGALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLL  145 (280)
T ss_dssp             HHHHCCCCCTSCSCHHHHHHHHHHHHHHHTTCHHHHHHHHTTTHHHHHHHHHHSCSCHHHHHHHHHHHHHTTSSCHHHHH
T ss_pred             cHHHHHHHHhhcCCHHHHHHHHHHHHHHccCCHHHHHHHHHCCHHHHHHHHhccCCCHHHHHHHHHHHHHHHhcCHHHHH
Confidence            3455555 66666677888899999998865444344444456777788877765 677888899999998865443333


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      .+...+.++.+..++. ..+..++..++.++.+++.... ....+.. ++++.|+.++.
T Consensus       146 ~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~  203 (280)
T 1XQS_B          146 QFLRLDGFSVLMRAMQ-QQVQKLKVKSAFLLQNLLVGHPEHKGTLCSMGMVQQLVALVR  203 (280)
T ss_dssp             HHHTTTHHHHHHHHHT-SSCHHHHHHHHHHHHHHHHHCGGGHHHHHTTTHHHHHHHHHT
T ss_pred             HHHHCCHHHHHHHHhh-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHhCCHHHHHHHHHc
Confidence            3444466777777776 4566788889999998887543 3333333 67777777764


No 118
>5MFI_B YIII(Dq.V2)4CqI, (KR)4; Designed armadillo repeat protein, peptide; 1.45A {synthetic construct}
Probab=97.18  E-value=3.4e-07  Score=83.37  Aligned_cols=134  Identities=19%  Similarity=0.243  Sum_probs=88.0  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++.+++...+.....+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus        47 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  126 (243)
T 5MFI_B           47 ALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKL  126 (243)
T ss_dssp             CHHHHHHTTTSSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHHTSSSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCcHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45566666766777888889999998886544433334445677778888877777888889999998876444333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus       127 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  182 (243)
T 5MFI_B          127 IEAGALSPLVKLLD-DASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLD  182 (243)
T ss_dssp             HHTTCHHHHHHTTT-SSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHGGG
T ss_pred             HHCCcHHHHHHHcc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHcc
Confidence            44456777777776 5566778888888888876322 2222222 45666665554


No 119
>5MFJ_B YIII(Dq.V2)4CqI, (KR)5; Designed armadillo repeat protein, peptide; 1.53A {synthetic construct}
Probab=97.18  E-value=3.4e-07  Score=83.37  Aligned_cols=134  Identities=19%  Similarity=0.243  Sum_probs=87.2  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++.+++...+.....+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus        47 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  126 (243)
T 5MFJ_B           47 ALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKL  126 (243)
T ss_dssp             CHHHHHHGGGCSCTTTC-CHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCcHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45566666766777888889999998886544433334445677778888877777888889999998876444333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus       127 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  182 (243)
T 5MFJ_B          127 IEAGALSPLVKLLD-DASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLD  182 (243)
T ss_dssp             HHTTCHHHHHHTTT-SSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHGGG
T ss_pred             HHCCcHHHHHHHcc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHcc
Confidence            44456777777776 5566778888888888876322 2222222 45666665554


No 120
>6SA6_A DARPin-Armadillo fusion A5; protein fusion, DARPin, Armadillo, shared; HET: EDO; 1.6A {synthetic construct}
Probab=97.16  E-value=3.9e-07  Score=91.03  Aligned_cols=134  Identities=25%  Similarity=0.292  Sum_probs=90.1  Template_Neff=12.400

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++.........+...++++.+..++...++.++..++.++.+++.........+
T Consensus       200 ~i~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  279 (397)
T 6SA6_A          200 ALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAV  279 (397)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             cHHHHHHHcCCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCcHHHHHHH
Confidence            45566667776777888899999999887544444444455678888888887788889999999999876443333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++.+++..... ...+.. ++++.|+.++.
T Consensus       280 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  335 (397)
T 6SA6_A          280 IDAGALPALVQLLS-SPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLS  335 (397)
T ss_dssp             HHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HhCChHHHHHHHhc-CCcHHHHHHHHHHHHHHhcCcHHHHHHHHhcChHHHHHHHhc
Confidence            34456777777776 45667778888888888654322 222222 56666666654


No 121
>6SA8_A ring-like DARPin-Armadillo fusion H83_D01, LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG; protein fusion, DARPin, Armadillo, shared; 2.4A {synthetic construct}
Probab=97.16  E-value=4e-07  Score=98.84  Aligned_cols=135  Identities=26%  Similarity=0.299  Sum_probs=93.7  Template_Neff=11.900

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++.+++...+.....+...+.++.+...+.+.+..++..++.++..++.........
T Consensus       220 ~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  299 (671)
T 6SA8_A          220 GALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQA  299 (671)
T ss_dssp             THHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             ChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHHHHHHcCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCcHHHHH
Confidence            34566667777777888999999999987654443334444567788888887777888899999999888654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK-EELIA-DALPVLADRVI  380 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~-~~Lve-giLe~Lv~LL~  380 (747)
                      +...++++.+...+. ..++.++..++.++..++...... ..+.. ++++.|..++.
T Consensus       300 ~~~~~~~~~L~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~l~~l~~~l~  356 (671)
T 6SA8_A          300 VIDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLS  356 (671)
T ss_dssp             HHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHHhChHHHHHHHhc-CCcHHHHHHHHHHHHHHhcCCcHHHHHHHhcChHHHHHHHhc
Confidence            444567778888886 556788889999999987643322 22333 66777777775


No 122
>1XQR_A HspBP1 protein; armadillo repeat, superhelical twist, CHAPERONE; HET: MSE; 2.1A {Homo sapiens} SCOP: a.118.1.21
Probab=97.14  E-value=4.4e-07  Score=88.91  Aligned_cols=134  Identities=22%  Similarity=0.180  Sum_probs=91.0  Template_Neff=11.300

Q NP_000290.2     246 TIPKAVQ-YLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP-NQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~-lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~-d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      +++.++. ++...++.++..++.+|.+++.........+...++++.+..++... +..++..++.++.+++........
T Consensus        82 ~~~~l~~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~l~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~  161 (296)
T 1XQR_A           82 GMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVAAIQEQVLGLGALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLL  161 (296)
T ss_dssp             HHHHCCCCCTTCSSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHHCSCHHHHHHHHHHHHHHHTTCHHHHH
T ss_pred             cHHHHHHHHHhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHhCCHHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHH
Confidence            3455555 66666677888899999998865443334444456777788777765 677888999999999865443333


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      .+...+.++.+...+. ..+..++..++.++.+++.... ....+.. ++++.|+.++.
T Consensus       162 ~~~~~~~i~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~i~~L~~ll~  219 (296)
T 1XQR_A          162 QFLRLDGFSVLMRAMQ-QQVQKLKVKSAFLLQNLLVGHPEHKGTLCSMGMVQQLVALVR  219 (296)
T ss_dssp             HHHHTTHHHHHHHHHH-SSCHHHHHHHHHHHHHHHHHCGGGHHHHHHTTHHHHHHHHHT
T ss_pred             HHHHCCHHHHHHHHhh-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHhCCHHHHHHHHHc
Confidence            3444456777777776 4567788889999999887543 3333333 67777777764


No 123
>4UAD_A Importin alpha import adaptor, Influenza; importin karyopherin complex NLS, PROTEIN; 2.42A {Homo sapiens}
Probab=97.13  E-value=4.5e-07  Score=91.78  Aligned_cols=368  Identities=15%  Similarity=0.162  Sum_probs=225.0  Template_Neff=12.900

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDE--SAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTN  321 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~--~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~  321 (747)
                      .+++.+...+.+.++.++..++.+|..+.....  .....+...++++.+...+.. .++.++..++.++..++......
T Consensus        23 ~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~  102 (479)
T 4UAD_A           23 VITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQ  102 (479)
T ss_dssp             CCCHHHHHHHTSSCHHHHHHHHHHHHHHHTCSSSCCHHHHHHSTTHHHHHHHHTTCTTCHHHHHHHHHHHHHHTTSCHHH
T ss_pred             hhHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCCCChhHhhcCcchHHHHHHHhhcCCCHHHHHHHHHHHHHHhCCCchH
Confidence            456666777777778889999999988876422  111122223567777777765 66778888999998887654333


Q NP_000290.2     322 KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVD  399 (747)
Q Consensus       322 ~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~  399 (747)
                      ...+...++++.+..++. ..++.++..++.++..++.... ....+.. ++++.|+.++...               .+
T Consensus       103 ~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~~  166 (479)
T 4UAD_A          103 TKIVIEAGAVPIFIELLN-SDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKS---------------TR  166 (479)
T ss_dssp             HHHHHHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHHHHC---------------CC
T ss_pred             HHHHHHcCHHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCChHHHHHHHhCCcHHHHHHHhhcC---------------Cc
Confidence            333333457777788776 5567888899999998887533 2223333 5666666666521               12


Q NP_000290.2     400 PEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVL  479 (747)
Q Consensus       400 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  479 (747)
                      +++-..+..+|..-..                     ............+.++.|...+..      -+..-...+...|
T Consensus       167 ~~~~~~a~~~l~~l~~---------------------~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l  219 (479)
T 4UAD_A          167 LTMTRNAVWALSNLCR---------------------GKNPPPEFAKVSPCLPVLSRLLFS------SDSDLLADACWAL  219 (479)
T ss_dssp             HHHHHHHHHHHHHHHC---------------------CCSSCCCGGGTGGGHHHHHHHTTC------CCHHHHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHc---------------------CCCCCchhhcccchHHHHHHHhcC------CCHHHHHHHHHHH
Confidence            3333333333321110                     000011111122334433333321      1111222233333


Q NP_000290.2     480 HNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKS  559 (747)
Q Consensus       480 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss  559 (747)
                      .++....                                                  ......+.+.++++.++.++. +
T Consensus       220 ~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~  248 (479)
T 4UAD_A          220 SYLSDGP--------------------------------------------------NEKIQAVIDSGVCRRLVELLM-H  248 (479)
T ss_dssp             HHHTSSS--------------------------------------------------HHHHHHHHHTTCHHHHHHGGG-C
T ss_pred             HHHhcCc--------------------------------------------------hHHHHHHHhCCHHHHHHHHhc-C
Confidence            3322100                                                  000111234567788888887 4


Q NP_000290.2     560 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVF  637 (747)
Q Consensus       560 ~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI  637 (747)
                      .++.++..++.+|.+++.....     ....+...++++.|..++.+.++.++..++.+|.+++... .. ..+...+++
T Consensus       249 ~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~  323 (479)
T 4UAD_A          249 NDYKVASPALRAVGNIVTGDDI-----QTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF  323 (479)
T ss_dssp             SCHHHHHHHHHHHHHHTTSCHH-----HHHHHHTTTCHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCH
T ss_pred             CCHHhHHHHHHHHHHHhcCCHH-----HHHHHHhcChHHHHHHHhhCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHH
Confidence            6778888999999998875332     1223334578888999998888889999999999998763 22 233445678


Q NP_000290.2     638 PEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS-QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       638 ~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~-s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      +.+..++.+      .++.++..++.+|.+++.. .+.....+.+.++++.+..++.+. ++.++..++.+|.+++...+
T Consensus       324 ~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~~~~  396 (479)
T 4UAD_A          324 PVLIEILQK------AEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLLTVM-DSKIVQVALNGLENILRLGE  396 (479)
T ss_dssp             HHHHHHHHH------SCHHHHHHHHHHHHHHHHHSCHHHHHHHHHTTCHHHHHGGGGCS-CHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHhc------cCHHHHHHHHHHHHHHHcCCCHHHHHHHHHcCcHHHHHHHhhcC-CHHHHHHHHHHHHHHHHHHH
Confidence            888888876      3678899999999999864 233444455556788888888866 78889999999999987654


Q NP_000290.2     717 LQ  718 (747)
Q Consensus       717 ~~  718 (747)
                      ..
T Consensus       397 ~~  398 (479)
T 4UAD_A          397 QE  398 (479)
T ss_dssp             HH
T ss_pred             Hh
Confidence            43


No 124
>5MFD_C YIIIM''6AII, Capsid decoration protein,pD_(KR)5; Designed armadillo repeat protein, peptide; HET: CA; 2.3A {synthetic construct}
Probab=97.07  E-value=6.1e-07  Score=84.84  Aligned_cols=114  Identities=25%  Similarity=0.284  Sum_probs=75.6  Template_Neff=13.300

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.+..++..++.++..+...........
T Consensus        89 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  168 (328)
T 5MFD_C           89 ALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAV  168 (328)
T ss_dssp             HHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666677788888999988876543333333344567777777777777888889999988875443332333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..+..++..++.++..++..
T Consensus       169 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  202 (328)
T 5MFD_C          169 IDAGALPALVQLLS-SPNEQILQEALWTLGNIASG  202 (328)
T ss_dssp             HHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHHTS
T ss_pred             HHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHHHcC
Confidence            33456666777775 45566777777777777653


No 125
>6HB3_B Protein HGH1; solenoid protein, Armadillo repeat, CHAPERONE; 3.0A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=97.07  E-value=7e-07  Score=92.28  Aligned_cols=121  Identities=9%  Similarity=-0.026  Sum_probs=77.4  Template_Neff=10.100

Q NP_000290.2     246 TIPKAVQYLSS---QDEKYQAIGAYYIQHTCFQDESAKQQVY--QLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTT  320 (747)
Q Consensus       246 iL~~Ll~lL~s---sd~eVr~sAL~aLsnLs~~~~~~~~~li--~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~  320 (747)
                      .++.|+.++..   .+..++..++.+|.++... ......+.  ..+.++.++.++...+..++..++.+|.+++.... 
T Consensus        52 ~i~~Lv~ll~~~~~~~~~~~~~al~~L~~l~~~-~~~~~~l~~~~~g~i~~L~~ll~~~~~~~~~~a~~~L~nl~~~~~-  129 (369)
T 6HB3_B           52 PIKDIIKMIMDPEHGTRVIIQQGVTILVNLSED-KLVRNIILSDDKKFLKFLVWKIVDLTNPNADIMCILLSNLAKDDG-  129 (369)
T ss_pred             cHHHHHHHHhCCCCCCHHHHHHHHHHHHHHcCC-HHHHHHHHhccCCcHHHHHHHhcCCCHHHHHHHHHHHHHHcCChH-
Confidence            56667777743   3567888899999998754 33344444  56788888888877667788888999988886432 


Q NP_000290.2     321 NKLET-------------------------RRQNGIREAVSLLRRTG------NAEIQKQLTGLLWNLSSTDELKEELIA  369 (747)
Q Consensus       321 ~~~~l-------------------------l~~~IL~~Ll~lL~ss~------d~eVr~~AL~aLsnLas~~~~~~~Lve  369 (747)
                      ....+                         ...++++.++.++. ..      +..++..++.+|.+++........+.+
T Consensus       130 ~~~~l~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~i~~Lv~~l~-~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~l~~  208 (369)
T 6HB3_B          130 ILAVLNIKRNSSGEEVDDGLKLAALNKEVFKSLRAMDCLMDCFV-KGYDKKLTKYASFNYLAFFFADISRFKLGRMYFIE  208 (369)
T ss_pred             HHHHHHhcCCCCCCHHHHHHHHHHHHHHHHHHCCcHHHHHHHhc-CCCCccCCCHHHHHHHHHHHHHHcCCHHHHHHHHH
Confidence            11212                         11345666666665 32      345666777777777765444444444


No 126
>3OPB_A SWI5-dependent HO expression protein 4; HEAT and ARM fold, Myosin; 2.9A {Saccharomyces cerevisiae}
Probab=97.06  E-value=7.2e-07  Score=100.91  Aligned_cols=156  Identities=12%  Similarity=0.164  Sum_probs=96.5  Template_Neff=10.500

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKE------KGLPQIARLLQSGNSDVVRSGASLL  619 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~------giI~~Ll~LL~s~d~eVr~~AL~aL  619 (747)
                      .++++.|+.++. +.+..++..++.+|.+++.....     ....+.+.      ++++.|+.++.+.++.++..++++|
T Consensus       605 ~~~~~~L~~ll~-~~~~~v~~~a~~~L~~L~~~~~~-----~~~~~~~~~~~~~~~~l~~L~~ll~~~~~~v~~~a~~~L  678 (778)
T 3OPB_A          605 KVYWSTIENLML-DENVPLQRSTLELISNMMSHPLT-----IAAKFFNLENPQSLRNFNILVKLLQLSDVESQRAVAAIF  678 (778)
T ss_dssp             HHHHHHHHHGGG-CSSHHHHHHHHHHHHHHHTSGGG-----TGGGTSCCSSHHHHHHHHHHHHGGGCSCHHHHHHHHHHH
T ss_pred             ccHHHHHHHHhh-CCCHHHHHHHHHHHHHHhcChhH-----HHHHhcCCCChhHHHhHHHHHHHhcCCCHHHHHHHHHHH
Confidence            356777777776 35677788888888888864321     12222332      6778888888777778888888888


Q NP_000290.2     620 SNMSRH-PLL-HRVMG-NQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA----K-QYFS-SSMLNNIIN  690 (747)
Q Consensus       620 snLa~~-~e~-~~ll~-~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~----~-~Lve-~giL~~Ll~  690 (747)
                      ++++.. +.. ...+. .++++.|+.++.+..    .+..++..++++|.+++...+...    . .+.+ .++++.|..
T Consensus       679 ~~l~~~~~~~~~~l~~~~~~i~~L~~~L~~~~----~~~~l~~~a~~aL~~L~~~~~~~~~~~~~~~l~~~~~~~~~L~~  754 (778)
T 3OPB_A          679 ANIATTIPLIAKELLTKKELIENAIQVFADQI----DDIELRQRLLMLFFGLFEVIPDNGTNEVYPLLQENQKLKDALNM  754 (778)
T ss_dssp             HHHHHHCHHHHHHHTTCHHHHHHHHHHHHHTT----TCHHHHHHHHHHHHHHHTTCCSTTTTSCCHHHHSCHHHHHHHHH
T ss_pred             HHHHccCHHHHHHHhcCccHHHHHHHHHHhCC----CCHHHHHHHHHHHHHHHhhCCcCCCccchhHHhcCHHHHHHHHH
Confidence            888755 222 23332 567777777776510    145678888888888886533222    0 1222 256777777


Q NP_000290.2     691 LCRSSA-SPKAAEAARLLLSDM  711 (747)
Q Consensus       691 LL~s~~-d~eVr~aAL~aLsnL  711 (747)
                      ++.... ++.++..+..+|.++
T Consensus       755 ~l~~~~~~~~~~~~~~~~L~~l  776 (778)
T 3OPB_A          755 SLKRGDSGPEFSAAIPVILAKI  776 (778)
T ss_dssp             HHSSSSSCSSTTSHHHHHHTTC
T ss_pred             HHhhCCCCHHHHHHHHHHHHhc
Confidence            776431 335555566555543


No 127
>4HXT_A De Novo Protein OR329; Structural Genomics, PSI-Biology, Protein Structure; 1.95A {artificial gene}
Probab=97.02  E-value=7.7e-07  Score=80.85  Aligned_cols=113  Identities=29%  Similarity=0.332  Sum_probs=76.4  Template_Neff=13.200

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETR  326 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll  326 (747)
                      ++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.+..++..++.++..++.........+.
T Consensus         4 ~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~   83 (252)
T 4HXT_A            4 VEKLVKLLTSTDSETQKEAARDLAEIASGPASAIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIV   83 (252)
T ss_dssp             HHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHH
T ss_pred             HHHHHHHcCCCCHHHHHHHHHHHHHHcCCCHHHHHHHHHCCHHHHHHHHhhCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
Confidence            44556666667778888999999988765433333334446677777777777778888999999988765433333333


Q NP_000290.2     327 RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       327 ~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ..++++.+...+. ..++.++..++.++.+++..
T Consensus        84 ~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  116 (252)
T 4HXT_A           84 DAGGVEVLVKLLT-STDSEVQKEAARALANIASG  116 (252)
T ss_dssp             HTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHTTS
T ss_pred             HCChHHHHHHHcc-CCCHHHHHHHHHHHHHHHcC
Confidence            3456667777775 45567777777887777653


No 128
>3GQ2_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.18A {Bos taurus}
Probab=97.01  E-value=9.1e-07  Score=98.43  Aligned_cols=136  Identities=15%  Similarity=0.144  Sum_probs=91.1  Template_Neff=10.100

Q NP_000290.2     245 LTIPKAVQYLSS--QDEKYQAIGAYYIQHTCFQDES-----------------AKQQVY-QLGGICKLVDLLRSPNQNVQ  304 (747)
Q Consensus       245 ~iL~~Ll~lL~s--sd~eVr~sAL~aLsnLs~~~~~-----------------~~~~li-~~~IL~~Ll~lL~s~d~eVr  304 (747)
                      .+++.|+..+..  .+..+...++.+|..++.....                 ....+. ..+.++.++.++...+..++
T Consensus        60 ~~l~~Li~~L~~~~~d~~~~~~al~~L~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~Ll~ll~~~~~~~~  139 (651)
T 3GQ2_A           60 QAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNDEEEEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVR  139 (651)
T ss_dssp             HHHHHHHHHHTTCTTCHHHHHHHHHHHHHHHCCSSSCC----------CHHHHHHHHHHTSHHHHHTHHHHTTCCCHHHH
T ss_pred             cHHHHHHHHHhcCCCCHHHHHHHHHHHHHHhCCCChHhhhhcccccchHHHHHHHHHHHhcCchHHHHHHHccCCCHHHH
Confidence            456667777764  4567788888888888764332                 112222 35667777777777777888


Q NP_000290.2     305 QAAAGALRNLVFRSTTNKL-ETR-RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST-DELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       305 ~~AL~aLs~La~~~~~~~~-~ll-~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~-~~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ..++.+|..++........ .+. ..+.+..++.++. ..+..++..++.+|.+++.. ......+.. ++++.|+.++.
T Consensus       140 ~~al~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~-~~~~~i~~~a~~~L~~l~~~~~~~~~~l~~~g~~~~L~~ll~  218 (651)
T 3GQ2_A          140 WPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLA-DSREVIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIIT  218 (651)
T ss_dssp             HHHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHGGGGG-CSSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhccHHHHHHHHhCccHHHHHHHHhc-CCCHHHHHHHHHHHHHHhCCCHHHHHHHHhCChHHHHHHHHH
Confidence            9999999988865432211 222 3456778888886 55677888999999999873 333333333 88888888886


Q NP_000290.2     381 I  381 (747)
Q Consensus       381 ~  381 (747)
                      .
T Consensus       219 ~  219 (651)
T 3GQ2_A          219 E  219 (651)
T ss_dssp             H
T ss_pred             H
Confidence            4


No 129
>3GRL_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.0A {Bos taurus}
Probab=97.01  E-value=9.1e-07  Score=98.43  Aligned_cols=136  Identities=15%  Similarity=0.144  Sum_probs=90.5  Template_Neff=10.100

Q NP_000290.2     245 LTIPKAVQYLSS--QDEKYQAIGAYYIQHTCFQDES-----------------AKQQVY-QLGGICKLVDLLRSPNQNVQ  304 (747)
Q Consensus       245 ~iL~~Ll~lL~s--sd~eVr~sAL~aLsnLs~~~~~-----------------~~~~li-~~~IL~~Ll~lL~s~d~eVr  304 (747)
                      .+++.|+..+..  .+..+...++.+|..++.....                 ....+. ..+.++.++.++...+..++
T Consensus        60 ~~l~~Li~~L~~~~~d~~~~~~al~~L~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~Ll~ll~~~~~~~~  139 (651)
T 3GRL_A           60 QAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNDEEEEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVR  139 (651)
T ss_dssp             CCHHHHHHHHHSCTTCHHHHHHHHHHHHHHHCCC--------------CHHHHHHHHHHHSTHHHHHHHHHTTCCCHHHH
T ss_pred             cHHHHHHHHHhcCCCCHHHHHHHHHHHHHHhCCCChHhhhhcccccchHHHHHHHHHHHhcCchHHHHHHHccCCCHHHH
Confidence            456667777764  4567788888888888764332                 112222 35667777777777777888


Q NP_000290.2     305 QAAAGALRNLVFRSTTNKL-ETR-RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST-DELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       305 ~~AL~aLs~La~~~~~~~~-~ll-~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~-~~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ..++.+|..++........ .+. ..+.+..++.++. ..+..++..++.+|.+++.. ......+.. ++++.|+.++.
T Consensus       140 ~~al~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~-~~~~~i~~~a~~~L~~l~~~~~~~~~~l~~~g~~~~L~~ll~  218 (651)
T 3GRL_A          140 WPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLA-DSREVIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIIT  218 (651)
T ss_dssp             HHHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHHGGGG-CSSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhccHHHHHHHHhCccHHHHHHHHhc-CCCHHHHHHHHHHHHHHhCCCHHHHHHHHhCChHHHHHHHHH
Confidence            9999999988865432211 222 3456778888886 55677888999999999873 333333333 88888888886


Q NP_000290.2     381 I  381 (747)
Q Consensus       381 ~  381 (747)
                      .
T Consensus       219 ~  219 (651)
T 3GRL_A          219 E  219 (651)
T ss_dssp             H
T ss_pred             H
Confidence            4


No 130
>4HXT_A De Novo Protein OR329; Structural Genomics, PSI-Biology, Protein Structure; 1.95A {artificial gene}
Probab=97.01  E-value=8.1e-07  Score=80.69  Aligned_cols=114  Identities=27%  Similarity=0.320  Sum_probs=76.2  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++.........+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus        45 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  124 (252)
T 4HXT_A           45 GVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAI  124 (252)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHhhCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCChHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666677888889999998876544333333444667777777777777888889999988876443332233


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++..++..
T Consensus       125 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  158 (252)
T 4HXT_A          125 VDAGGVEVLVKLLT-STDSEVQKEAARALANIASG  158 (252)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTS
T ss_pred             HHCCHHHHHHHHhh-CCCHHHHHHHHHHHHHHHcC
Confidence            33356666666665 45567777788888877764


No 131
>4PLS_B Arm00010; PEPTIDE BINDING PROTEIN, designed armadillo; HET: CA; 2.35A {synthetic construct}
Probab=97.00  E-value=8.3e-07  Score=82.05  Aligned_cols=114  Identities=25%  Similarity=0.284  Sum_probs=75.7  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.++.++..++.++..++.........+
T Consensus        44 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  123 (281)
T 4PLS_B           44 ALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAV  123 (281)
T ss_dssp             HHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCHHHHHHHHhCCcHHHHHHHcCCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            45566666666777888889999998876443333333444577777777777777888888898888876433332333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++..++..
T Consensus       124 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  157 (281)
T 4PLS_B          124 IDAGALPALVQLLS-SPNEQILQEALWTLGNIASG  157 (281)
T ss_dssp             HHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHTTS
T ss_pred             HHCCHHHHHHHHcc-CCCHHHHHHHHHHHHHHHcC
Confidence            33456666777665 44566777777777776653


No 132
>5IZA_A Adenomatous polyposis coli protein, ACE-GLY-GLY-GLU-ALA-LEU-ALA-TRP-NH2; APC, ASEF, Colon CANCER, Drug; 1.5A {Homo sapiens}
Probab=96.99  E-value=9.5e-07  Score=87.41  Aligned_cols=114  Identities=22%  Similarity=0.254  Sum_probs=75.1  Template_Neff=12.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQ-DESAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~-~~~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .+++.+..++.+.++.++..++.++.+++.. .......+...++++.+..++.. .+..++..++.+|.+++.......
T Consensus       127 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~  206 (354)
T 5IZA_A          127 GCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENK  206 (354)
T ss_dssp             HHHHHHHHGGGCSCHHHHHHHHHHHHHHHTTCCHHHHHHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHHTTCHHHH
T ss_pred             hHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCChhHHHHHHHCCHHHHHHHHHHhcCCHHHHHHHHHHHHHHHcCChHhH
Confidence            3455666677766778888999999998874 22223334445677778888776 677888889999999886533333


Q NP_000290.2     323 LETRR-QNGIREAVSLLRR---TGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       323 ~~ll~-~~IL~~Ll~lL~s---s~d~eVr~~AL~aLsnLa  358 (747)
                      ..+.. .++++.+..++..   ..+..++..++.++..+.
T Consensus       207 ~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~L~~l~  246 (354)
T 5IZA_A          207 ADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVS  246 (354)
T ss_dssp             HHHHTSTTHHHHHHHHTCSSCSSCCHHHHHHHHHHHHHHH
T ss_pred             HHHHhhccHHHHHHHHHhhcCCCCcHHHHHHHHHHHHHHH
Confidence            33444 4667777777651   112456666777777765


No 133
>5IZ8_A Adenomatous polyposis coli protein, ACE-ALA-GLY-GLU-ALA-LEU-ALA-ASP-NH2; APC, ASEF, Colon CANCER, Drug; HET: PGE; 3.06A {Homo sapiens}
Probab=96.97  E-value=1e-06  Score=87.19  Aligned_cols=113  Identities=22%  Similarity=0.270  Sum_probs=74.6  Template_Neff=12.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQ-DESAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~-~~~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      +++.+..++.+.++.++..++.++.+++.. .......+...++++.+..++.. .+..++..++.+|.+++........
T Consensus       128 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~  207 (354)
T 5IZ8_A          128 CMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKA  207 (354)
T ss_dssp             HHHHHHHGGGSSCHHHHHHHHHHHHHHHTTCCHHHHHHHHHTTHHHHHHHHHHHCCSHHHHHHHHHHHHHHHTSCHHHHH
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCChhHHHHHHHCCHHHHHHHHHHhcCCHHHHHHHHHHHHHHHcCChHhHH
Confidence            455666677666778888999999998874 22223334445677778888776 6778888899999998865333333


Q NP_000290.2     324 ETRR-QNGIREAVSLLRR---TGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       324 ~ll~-~~IL~~Ll~lL~s---s~d~eVr~~AL~aLsnLa  358 (747)
                      .+.. .++++.+..++..   ..+..++..++.++..+.
T Consensus       208 ~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~L~~l~  246 (354)
T 5IZ8_A          208 DICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVS  246 (354)
T ss_dssp             HHHTSTTHHHHHHHHTTCCCTTSCCHHHHHHHHHHHHHH
T ss_pred             HHHhhccHHHHHHHHHhhcCCCCcHHHHHHHHHHHHHHH
Confidence            3444 4667777777651   112456666777777765


No 134
>6SA7_B DARPin-Armadillo fusion C8long83; protein fusion, DARPin, Armadillo, shared; 3.3A {synthetic construct}
Probab=96.96  E-value=1.1e-06  Score=90.60  Aligned_cols=135  Identities=25%  Similarity=0.264  Sum_probs=91.1  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.+|.+++.........+...++++.+..++...++.++..++.+|..++.........+
T Consensus       342 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~  421 (510)
T 6SA7_B          342 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV  421 (510)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHHTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            34445555556667788888888888876544433334445677788888877778888899999998875544433344


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVII  381 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~  381 (747)
                      ...++++.+..++. ..++.++..++.++..++.... ....+.. ++++.|..++..
T Consensus       422 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~  478 (510)
T 6SA7_B          422 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSH  478 (510)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHGGGC
T ss_pred             HHcCcHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCCchHHHHHHHCCHHHHHHHHhhc
Confidence            44567778888886 5677889999999999985432 2222333 667777776653


No 135
>4V3Q_A YIII_M4_AII; DE NOVO PROTEIN, PROTEIN ENGINEERING; HET: GOL, CA; 1.8A {SYNTHETIC CONSTRUCT}
Probab=96.95  E-value=1.1e-06  Score=80.29  Aligned_cols=135  Identities=24%  Similarity=0.251  Sum_probs=89.9  Template_Neff=12.900

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.+..++..++.++.+++.........+...++++.+...+.+.+..++..++.++..++.........
T Consensus        92 ~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~  171 (247)
T 4V3Q_A           92 GALPALVQLLSSPNEQILQEALWTLGNIASGGDEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGDEQIQA  171 (247)
T ss_dssp             THHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             CcHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHH
Confidence            34556666666667788888899998887654433333344567777888777777788888999998887654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ....++++.+...+. ..++.++..++.++..++.... ....+.. ++++.|..++.
T Consensus       172 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  228 (247)
T 4V3Q_A          172 VIDAGALPALVQLLS-SPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQS  228 (247)
T ss_dssp             HHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCHHHHHHHHHh
Confidence            334456777777776 5567788889999998886532 2222333 66677776665


No 136
>5Z8H_A Adenomatous polyposis coli protein, Peptide; APC, inhibitor, PROTEIN BINDING-INHIBITOR complex; HET: PHQ, GOL; 1.79A {Homo sapiens}
Probab=96.93  E-value=1.2e-06  Score=84.95  Aligned_cols=134  Identities=21%  Similarity=0.263  Sum_probs=83.9  Template_Neff=12.500

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQ-DESAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~-~~~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .+++.+...+.+.++.++..++.++.+++.. .......+...++++.+..++.. .++.++..++.++.+++.......
T Consensus       122 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~  201 (339)
T 5Z8H_A          122 GCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENK  201 (339)
T ss_pred             ChHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCCHHHHHHHHHCCcHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHH
Confidence            3455666667666778888999999998874 22223334445677778887776 577788889999999886444333


Q NP_000290.2     323 LETRR-QNGIREAVSLLRRTGN----AEIQKQLTGLLWNLSS----TDELKEELIA-DALPVLADRV  379 (747)
Q Consensus       323 ~~ll~-~~IL~~Ll~lL~ss~d----~eVr~~AL~aLsnLas----~~~~~~~Lve-giLe~Lv~LL  379 (747)
                      ..+.. .++++.+..++. ..+    ..++..++.++.++..    .......+.. ++++.++.++
T Consensus       202 ~~~~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l  267 (339)
T 5Z8H_A          202 ADICAVDGALAFLVGTLT-YRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHL  267 (339)
T ss_pred             HHHHHhcChHHHHHHHhc-CCCCCCCHHHHHHHHHHHHHHHHhhccCHHHHHHHHHCCHHHHHHHHH
Confidence            34444 466777777775 222    5667777777777752    2222222222 5555555555


No 137
>5AEI_B DESIGNED ARMADILLO REPEAT PROTEIN YIIIM5AII; DE NOVO PROTEIN, PROTEIN-PEPTIDE COMPLEX; HET: CA, ACT; 1.83A {SYNTHETIC CONSTRUCT}
Probab=96.89  E-value=1.4e-06  Score=80.58  Aligned_cols=112  Identities=27%  Similarity=0.322  Sum_probs=75.3  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++..++...+.....+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus       173 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  252 (286)
T 5AEI_B          173 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAV  252 (286)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHccCCCHHHHHHHHHHHHHHhCCCHHHHHHH
Confidence            45556666666677788888999988876544333333344567777777777777888889999988885544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ...++++.+...+. ..++.++..++.++..++
T Consensus       253 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~  284 (286)
T 5AEI_B          253 KEAGALEKLEQLQS-HENEKIQKEAQEALEKLQ  284 (286)
T ss_dssp             HHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHH
T ss_pred             HHcCHHHHHHHHhh-CCCHHHHHHHHHHHHHHh
Confidence            34456677777776 456677777877777664


No 138
>5IZA_A Adenomatous polyposis coli protein, ACE-GLY-GLY-GLU-ALA-LEU-ALA-TRP-NH2; APC, ASEF, Colon CANCER, Drug; 1.5A {Homo sapiens}
Probab=96.88  E-value=1.5e-06  Score=85.84  Aligned_cols=124  Identities=24%  Similarity=0.343  Sum_probs=84.2  Template_Neff=12.000

Q NP_000290.2     258 DEKYQAIGAYYIQHTCFQDESAKQQVYQ-LGGICKLVDLLRSPNQNVQQAAAGALRNLVFR-STTNKLETRRQNGIREAV  335 (747)
Q Consensus       258 d~eVr~sAL~aLsnLs~~~~~~~~~li~-~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~-~~~~~~~ll~~~IL~~Ll  335 (747)
                      +..++..++.++.+++.........+.. .++++.+..++...++.++..++.++.+++.. .......+...++++.+.
T Consensus        97 ~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~  176 (354)
T 5IZA_A           97 SITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALM  176 (354)
T ss_dssp             HHHHHHHHHHHHHHHHTTCHHHHHHHHHCHHHHHHHHHGGGCSCHHHHHHHHHHHHHHHTTCCHHHHHHHHHTTHHHHHH
T ss_pred             CHHHHHHHHHHHHHHhcCCHHHHHHHHccchHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCChhHHHHHHHCCHHHHHH
Confidence            5677888888888887644333333333 46777888888777788889999999998864 222233344456777788


Q NP_000290.2     336 SLLRRTGNAEIQKQLTGLLWNLSST-DELKEELIA--DALPVLADRVII  381 (747)
Q Consensus       336 ~lL~ss~d~eVr~~AL~aLsnLas~-~~~~~~Lve--giLe~Lv~LL~~  381 (747)
                      .++....++.++..++.++.+++.. ......+..  ++++.|+.++..
T Consensus       177 ~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~  225 (354)
T 5IZA_A          177 ECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTY  225 (354)
T ss_dssp             HHHHHCCCHHHHHHHHHHHHHHHTTCHHHHHHHHTSTTHHHHHHHHTCS
T ss_pred             HHHHhcCCHHHHHHHHHHHHHHHcCChHhHHHHHhhccHHHHHHHHHhh
Confidence            8876225677888899999999876 444434433  667777777664


No 139
>5IZ8_A Adenomatous polyposis coli protein, ACE-ALA-GLY-GLU-ALA-LEU-ALA-ASP-NH2; APC, ASEF, Colon CANCER, Drug; HET: PGE; 3.06A {Homo sapiens}
Probab=96.88  E-value=1.6e-06  Score=85.78  Aligned_cols=124  Identities=24%  Similarity=0.343  Sum_probs=84.2  Template_Neff=12.000

Q NP_000290.2     258 DEKYQAIGAYYIQHTCFQDESAKQQVYQ-LGGICKLVDLLRSPNQNVQQAAAGALRNLVFR-STTNKLETRRQNGIREAV  335 (747)
Q Consensus       258 d~eVr~sAL~aLsnLs~~~~~~~~~li~-~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~-~~~~~~~ll~~~IL~~Ll  335 (747)
                      +..++..++.++.+++.........+.. .++++.+..++...++.++..++.++.+++.. .......+...++++.+.
T Consensus        97 ~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~  176 (354)
T 5IZ8_A           97 SITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALM  176 (354)
T ss_dssp             HHHHHHHHHHHHHHHHTTCHHHHHHHHHCHHHHHHHHHGGGSSCHHHHHHHHHHHHHHHTTCCHHHHHHHHHTTHHHHHH
T ss_pred             CHHHHHHHHHHHHHHhcCCHHHHHHHHccchHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCChhHHHHHHHCCHHHHHH
Confidence            5677888888888887644333333333 46777888888777788888999999998864 222233344456777788


Q NP_000290.2     336 SLLRRTGNAEIQKQLTGLLWNLSST-DELKEELIA--DALPVLADRVII  381 (747)
Q Consensus       336 ~lL~ss~d~eVr~~AL~aLsnLas~-~~~~~~Lve--giLe~Lv~LL~~  381 (747)
                      .++....++.++..++.+|.+++.. ......+..  ++++.|+.++..
T Consensus       177 ~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~  225 (354)
T 5IZ8_A          177 ECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTY  225 (354)
T ss_dssp             HHHHHCCSHHHHHHHHHHHHHHHTSCHHHHHHHHTSTTHHHHHHHHTTC
T ss_pred             HHHHhcCCHHHHHHHHHHHHHHHcCChHhHHHHHhhccHHHHHHHHHhh
Confidence            8876225677888899999999876 444333433  667777777664


No 140
>3NMZ_A APC variant protein, Rho guanine; protein-protein complex, armadillo repeats, CELL; 3.01A {Homo sapiens}
Probab=96.87  E-value=1.6e-06  Score=88.90  Aligned_cols=135  Identities=18%  Similarity=0.233  Sum_probs=88.1  Template_Neff=12.000

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQ-LGGICKLVDLLR----SPNQNVQQAAAGALRNLV---F  316 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~-~~IL~~Ll~lL~----s~d~eVr~~AL~aLs~La---~  316 (747)
                      +++.+..++. ..+..++..++.+|.+++...+.....+.. .++++.+..++.    ..+..++..++.++.+++   .
T Consensus       287 ~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~a~~~l~~l~~~~~  366 (458)
T 3NMZ_A          287 SVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIA  366 (458)
T ss_pred             HHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCchhHHHHHHhcChHHHHHHHHcCCCCCCCHHHHHHHHHHHHHHHHHhc
Confidence            4555666665 456778888999999988743333333333 566777777765    224566777888887765   2


Q NP_000290.2     317 RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS-TDELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       317 ~~~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas-~~~~~~~Lve-giLe~Lv~LL~~  381 (747)
                      ........+...++++.+..++. ..++.++..++.+|..++. .......+.. ++++.|..++..
T Consensus       367 ~~~~~~~~l~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~l~~~~~~~~L~~ll~~  432 (458)
T 3NMZ_A          367 TNEDHRQILRENNCLQTLLQHLK-SHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHS  432 (458)
T ss_pred             CCHHHHHHHHHCCcHHHHHHHhC-CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCcHHHHHHHHhC
Confidence            22223333344467777888886 5567889999999999987 3444444544 788888887754


No 141
>6SA7_B DARPin-Armadillo fusion C8long83; protein fusion, DARPin, Armadillo, shared; 3.3A {synthetic construct}
Probab=96.87  E-value=1.6e-06  Score=89.20  Aligned_cols=134  Identities=26%  Similarity=0.306  Sum_probs=91.2  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.+|.+++.........+...++++.+...+.+.++.++..++.+|..++.........+
T Consensus       300 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  379 (510)
T 6SA7_B          300 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV  379 (510)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHHSSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHHHHHhCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHHHH
Confidence            45566666666677888889999998876544333344445677778888877778888899999999886544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.+|..++.... ....+.. ++++.|+.++.
T Consensus       380 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  435 (510)
T 6SA7_B          380 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLS  435 (510)
T ss_dssp             HHTTHHHHHHHHHT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHcChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCcHHHHHHHhc
Confidence            44467777887776 5577888889999998865432 2223333 66777777664


No 142
>5TBK_C Importin subunit alpha-3, Regulator of; Nuclear Import, Importin alpha, RCC1; 3.45A {Homo sapiens}
Probab=96.87  E-value=1.7e-06  Score=90.04  Aligned_cols=367  Identities=17%  Similarity=0.192  Sum_probs=215.7  Template_Neff=12.200

Q NP_000290.2     246 TIPKAVQYLSSQ-DEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ss-d~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+... ++.++..++.++..++.........+...++++.+..++.+.++.++..++.++..++.........
T Consensus       115 ~i~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  194 (521)
T 5TBK_C          115 ILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDY  194 (521)
T ss_dssp             HHHHHHHHHHCCSCHHHHHHHHHHHHHHHTSCHHHHHHHHTTTCHHHHHHHTTCSCHHHHHHHHHHHHHHHHHCHHHHHH
T ss_pred             cHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCChHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            445555555543 6678888888888887654333333334467777888887777888999999999888654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...+++..+...+....+..++..++.++..++..........  .++++.+..++...                ++++
T Consensus       195 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~v  258 (521)
T 5TBK_C          195 VISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHT----------------DVNI  258 (521)
T ss_dssp             HHHTTCHHHHHTTCCTTSCHHHHHHHHHHHHHHHCCCSSCCCHHHHHHHHHHHHHHTTCS----------------CHHH
T ss_pred             HHHCCcHHHHHHHhCCCCCHHHHHHHHHHHHHHHcCCCCCCCHHHHHHHHHHHHHHhhCC----------------CHHH
Confidence            33445677777777533344678888888888876533221111  15566666665431                2334


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..+|..-...      .+              ..++.+. -.+++..|...+..      .+..-...++..|.++
T Consensus       259 ~~~a~~~L~~l~~~------~~--------------~~~~~~~-~~~~~~~l~~~l~~------~~~~v~~~a~~~L~~l  311 (521)
T 5TBK_C          259 LVDTVWALSYLTDA------GN--------------EQIQMVI-DSGIVPHLVPLLSH------QEVKVQTAALRAVGNI  311 (521)
T ss_dssp             HHHHHHHHHHHHHH------CH--------------HHHHHHH-HTTCHHHHGGGGGC------SSHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhcc------Ch--------------HHHHHHH-HCChHHHHHHHhcC------CCHHHHHHHHHHHHHH
Confidence            33343333221100      00              0000000 02333434333321      0111112222223332


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ...-                                                  ......+.+.++++.|..++. +.++
T Consensus       312 ~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~  340 (521)
T 5TBK_C          312 VTGT--------------------------------------------------DEQTQVVLNCDALSHFPALLT-HPKE  340 (521)
T ss_dssp             HTSC--------------------------------------------------HHHHHHHHHTTCGGGHHHHHT-CSCH
T ss_pred             HcCC--------------------------------------------------HHHHHHHHhCCHHHhHHHHhh-CCCH
Confidence            2110                                                  000112234467788888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGNQVFPE  639 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~giI~~  639 (747)
                      .++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.. . .. ..+...++++.
T Consensus       341 ~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~l~~~~~~~~  415 (521)
T 5TBK_C          341 KINKEAVWFLSNITAGNQQ-----QVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPP  415 (521)
T ss_dssp             HHHHHHHHHHHHHTTSCHH-----HHHHHHTTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHSCHHHHHHHHTTTCHHH
T ss_pred             HHHHHHHHHHHHHhCCCHH-----HHHHHHHCCcHHHHHHHHHhCCHHHHHHHHHHHHHHHccCCHHHHHHHHHCCCHHH
Confidence            8888999999999865332     223334557888888888887888999999999999864 2 11 22233467788


Q NP_000290.2     640 VTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA----KQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       640 Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~----~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      |..++..      .++.++..++.+|.+++...+...    ..+.+.++++.|..++.+. ++.++..++.+|.+++...
T Consensus       416 L~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~l~~~~~~~~l~~ll~~~-~~~v~~~a~~~L~~l~~~~  488 (521)
T 5TBK_C          416 FCNLLTV------KDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHE-NEDIYKLAYEIIDQFFSSD  488 (521)
T ss_dssp             HHGGGGS------SCHHHHHHHHHHHHHHHHHCSTTHHHHHHHHHHTTHHHHHHHHCSTT-CHHHHHHHHHHHHHHCCC-
T ss_pred             HHHHcCC------CCHHHHHHHHHHHHHHHHHhHHhHHHHHHHHHHCCHHHHHHHHhcCC-CHHHHHHHHHHHHHhcCCC
Confidence            8888765      367888899999999887533211    2233446778888888766 7889999999999999766


Q NP_000290.2     716 ELQ  718 (747)
Q Consensus       716 ~~~  718 (747)
                      +..
T Consensus       489 ~~~  491 (521)
T 5TBK_C          489 DID  491 (521)
T ss_dssp             ---
T ss_pred             CCC
Confidence            543


No 143
>5TBK_D Importin subunit alpha-3, Regulator of; Nuclear Import, Importin alpha, RCC1; 3.45A {Homo sapiens}
Probab=96.87  E-value=1.7e-06  Score=90.04  Aligned_cols=367  Identities=17%  Similarity=0.192  Sum_probs=215.0  Template_Neff=12.200

Q NP_000290.2     246 TIPKAVQYLSSQ-DEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ss-d~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+... ++.++..++.++..++.........+...++++.+..++.+.++.++..++.++..++.........
T Consensus       115 ~i~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  194 (521)
T 5TBK_D          115 ILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDY  194 (521)
T ss_dssp             HHHHHHHHHHCCSCHHHHHHHHHHHHHHHTSCHHHHHHHHTTTCHHHHHHHTTCSCHHHHHHHHHHHHHHHHHCHHHHHH
T ss_pred             cHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCChHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            445555555543 6678888888888887654333333334467777888887777888999999999888654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...+++..+...+....+..++..++.++..++..........  .++++.+..++...                ++++
T Consensus       195 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~v  258 (521)
T 5TBK_D          195 VISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHT----------------DVNI  258 (521)
T ss_dssp             HHHTCCHHHHHTTCCTTSCHHHHHHHHHHHHHHHCCCSSCCCHHHHHHHHHHHHHHTTCS----------------CHHH
T ss_pred             HHHCCcHHHHHHHhCCCCCHHHHHHHHHHHHHHHcCCCCCCCHHHHHHHHHHHHHHhhCC----------------CHHH
Confidence            33445677777777533344678888888888876533221111  15566666665431                2334


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..+|..-...      .+              ..++.+. -.+++..|...+..      .+..-...++..|.++
T Consensus       259 ~~~a~~~L~~l~~~------~~--------------~~~~~~~-~~~~~~~l~~~l~~------~~~~v~~~a~~~L~~l  311 (521)
T 5TBK_D          259 LVDTVWALSYLTDA------GN--------------EQIQMVI-DSGIVPHLVPLLSH------QEVKVQTAALRAVGNI  311 (521)
T ss_dssp             HHHHHHHHHHHHHH------CH--------------HHHHHHH-HTTCHHHHGGGGGC------SSHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhcc------Ch--------------HHHHHHH-HCChHHHHHHHhcC------CCHHHHHHHHHHHHHH
Confidence            33343333221100      00              0000000 02333434333321      0111112222223332


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ...-                                                  ......+.+.++++.|..++. +.++
T Consensus       312 ~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~  340 (521)
T 5TBK_D          312 VTGT--------------------------------------------------DEQTQVVLNCDALSHFPALLT-HPKE  340 (521)
T ss_dssp             HTSC--------------------------------------------------HHHHHHHHHTTCGGGHHHHHH-CSCH
T ss_pred             HcCC--------------------------------------------------HHHHHHHHhCCHHHhHHHHhh-CCCH
Confidence            2110                                                  000112234467788888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGNQVFPE  639 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~giI~~  639 (747)
                      .++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.. . .. ..+...++++.
T Consensus       341 ~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~l~~~~~~~~  415 (521)
T 5TBK_D          341 KINKEAVWFLSNITAGNQQ-----QVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPP  415 (521)
T ss_dssp             HHHHHHHHHHHHHTTSCHH-----HHHHHHTTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHSCHHHHHHHHTTTCHHH
T ss_pred             HHHHHHHHHHHHHhCCCHH-----HHHHHHHCCcHHHHHHHHHhCCHHHHHHHHHHHHHHHccCCHHHHHHHHHCCCHHH
Confidence            8888999999999865332     223334557888888888887888999999999999864 2 11 22233467788


Q NP_000290.2     640 VTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA----KQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       640 Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~----~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      |..++..      .++.++..++.+|.+++...+...    ..+.+.++++.|..++.+. ++.++..++.+|.+++...
T Consensus       416 L~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~l~~~~~~~~l~~ll~~~-~~~v~~~a~~~L~~l~~~~  488 (521)
T 5TBK_D          416 FCNLLTV------KDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHE-NEDIYKLAYEIIDQFFSSD  488 (521)
T ss_dssp             HHGGGGS------SCHHHHHHHHHHHHHHHHHCSTTHHHHHHHHHHTTHHHHHHHHTTCS-CHHHHHHHHHHHHHHCC--
T ss_pred             HHHHcCC------CCHHHHHHHHHHHHHHHHHhHHhHHHHHHHHHHCCHHHHHHHHhcCC-CHHHHHHHHHHHHHhcCCC
Confidence            8888765      367888899999999887533211    2233446778888888766 7889999999999999766


Q NP_000290.2     716 ELQ  718 (747)
Q Consensus       716 ~~~  718 (747)
                      +..
T Consensus       489 ~~~  491 (521)
T 5TBK_D          489 DID  491 (521)
T ss_dssp             ---
T ss_pred             CCC
Confidence            543


No 144
>6HB1_A Protein HGH1; solenoid protein, Armadillo repeat, CHAPERONE; 2.33A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=96.86  E-value=1.8e-06  Score=89.00  Aligned_cols=169  Identities=9%  Similarity=0.050  Sum_probs=120.8  Template_Neff=10.100

Q NP_000290.2     547 DAIRTYLNLMGK--SKKDATLEACAGALQNLTASKGLMSSGMSQLIGL--KEKGLPQIARLLQSGNSDVVRSGASLLSNM  622 (747)
Q Consensus       547 G~I~~LL~LL~s--s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~lli--e~giI~~Ll~LL~s~d~eVr~~AL~aLsnL  622 (747)
                      ++++.|+.++..  +.++.++..++++|.+++....      ....+.  +.++++.|+.++.+.+..++..++++|.++
T Consensus        51 ~~i~~Lv~ll~~~~~~~~~~~~~al~~L~~l~~~~~------~~~~l~~~~~g~i~~L~~ll~~~~~~~~~~a~~~L~nl  124 (369)
T 6HB1_A           51 RPIKDIIKMIMDPEHGTRVIIQQGVTILVNLSEDKL------VRNIILSDDKKFLKFLVWKIVDLTNPNADIMCILLSNL  124 (369)
T ss_dssp             HHHHHHHHHHHCTTTCCHHHHHHHHHHHHHHTTSHH------HHHCCCCCSTHHHHHHHHHHHCTTCTTHHHHHHHHHHH
T ss_pred             hHHHHHHHHHhCcccCcHHHHHHHHHHHHHHhCCHH------HHHHHhhcChHHHHHHHHHHHcCCCccHHHHHHHHHHH
Confidence            588999999952  1356788899999999986532      244445  689999999999887778889999999999


Q NP_000290.2     623 SRHPLLH-RV-------------------------MGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA  676 (747)
Q Consensus       623 a~~~e~~-~l-------------------------l~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~  676 (747)
                      +...... .+                         ...++++.|+.++.........++.++..++++|.+|+.. +..+
T Consensus       125 ~~~~~~~~~l~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~i~~Lv~~l~~~~~~~~~~~~~~~~a~~~l~~l~~~-~~~~  203 (369)
T 6HB1_A          125 AKDDGILAVLNIKRNSSGEEVDDGLKLAALNKEVFKSLRAMDCLMDCFVKGYDKKLTKYASFNYLAFFFADISRF-KLGR  203 (369)
T ss_dssp             TTSGGGGGGGGCBCSCSSSEEETTEEECCCCTTTCCCSBHHHHHHHHHHHCGGGSSCSSCCCTTHHHHHHHHTTS-HHHH
T ss_pred             ccChhHHHHHhhcCCCCCCchhhhHHHHHHcHHHHHHhhHHHHHHHHHhhcCcccCCchhchHHHHHHHHHHcCC-HHHH
Confidence            9864332 22                         1246778888887652000000456788899999999875 5666


Q NP_000290.2     677 KQYFSSS------MLNNIINLCR-SSASPKAAEAARLLLSDMWSSKELQGVLRQ  723 (747)
Q Consensus       677 ~~Lve~g------iL~~Ll~LL~-s~~d~eVr~aAL~aLsnL~~~~~~~~~~~~  723 (747)
                      ..+.+.+      .+..++.++. +. +..++..++.+|.+++.+.+....+..
T Consensus       204 ~~l~~~g~~~~~~~l~~ll~~l~~~~-~~~~~~~a~~~L~nl~~~~~~~~~i~~  256 (369)
T 6HB1_A          204 MYFIEEQEYDGVVPISKLLVFTEKYD-AKVRREGVASTIKNSLFDSETHERLLK  256 (369)
T ss_dssp             HHHHSCCTTTCCCGGGGTGGGGGCTT-CHHHHHHHHHHHHHHTCCGGGHHHHHH
T ss_pred             HHHhhcccccCcccHHHHHHHhcccC-CHHHHHHHHHHHHHHhcCHHHHHHHhc
Confidence            6677766      4666666665 34 678899999999999988775544443


No 145
>6HB2_D Protein HGH1; solenoid protein, Armadillo repeat, CHAPERONE; HET: MSE; 2.7A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=96.86  E-value=1.8e-06  Score=89.00  Aligned_cols=169  Identities=9%  Similarity=0.050  Sum_probs=120.8  Template_Neff=10.100

Q NP_000290.2     547 DAIRTYLNLMGK--SKKDATLEACAGALQNLTASKGLMSSGMSQLIGL--KEKGLPQIARLLQSGNSDVVRSGASLLSNM  622 (747)
Q Consensus       547 G~I~~LL~LL~s--s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~lli--e~giI~~Ll~LL~s~d~eVr~~AL~aLsnL  622 (747)
                      ++++.|+.++..  +.++.++..++++|.+++....      ....+.  +.++++.|+.++.+.+..++..++++|.++
T Consensus        51 ~~i~~Lv~ll~~~~~~~~~~~~~al~~L~~l~~~~~------~~~~l~~~~~g~i~~L~~ll~~~~~~~~~~a~~~L~nl  124 (369)
T 6HB2_D           51 RPIKDIIKMIMDPEHGTRVIIQQGVTILVNLSEDKL------VRNIILSDDKKFLKFLVWKIVDLTNPNADIMCILLSNL  124 (369)
T ss_dssp             HHHHHHHHHHHCTTTCCHHHHHHHHHHHHHHTTSHH------HHHCCCCCCTHHHHHHHHHHSCTTCTTHHHHHHHHHHH
T ss_pred             hHHHHHHHHHhCcccCcHHHHHHHHHHHHHHhCCHH------HHHHHhhcChHHHHHHHHHHHcCCCccHHHHHHHHHHH
Confidence            588999999952  1356788899999999986532      244445  689999999999887778889999999999


Q NP_000290.2     623 SRHPLLH-RV-------------------------MGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA  676 (747)
Q Consensus       623 a~~~e~~-~l-------------------------l~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~  676 (747)
                      +...... .+                         ...++++.|+.++.........++.++..++++|.+|+.. +..+
T Consensus       125 ~~~~~~~~~l~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~i~~Lv~~l~~~~~~~~~~~~~~~~a~~~l~~l~~~-~~~~  203 (369)
T 6HB2_D          125 AKDDGILAVLNIKRNSSGEEVDDGLKLAALNKEVFKSLRAMDCLMDCFVKGYDKKLTKYASFNYLAFFFADISRF-KLGR  203 (369)
T ss_dssp             TTSGGGGGGGGCBCSCSSSEEETTEEECCCCTTTCCCSBHHHHHHHHHHHHGGGSSCSSCCCTTHHHHHHHHTTS-HHHH
T ss_pred             ccChhHHHHHhhcCCCCCCchhhhHHHHHHcHHHHHHhhHHHHHHHHHhhcCcccCCchhchHHHHHHHHHHcCC-HHHH
Confidence            9864332 22                         1246778888887652000000456788899999999875 5666


Q NP_000290.2     677 KQYFSSS------MLNNIINLCR-SSASPKAAEAARLLLSDMWSSKELQGVLRQ  723 (747)
Q Consensus       677 ~~Lve~g------iL~~Ll~LL~-s~~d~eVr~aAL~aLsnL~~~~~~~~~~~~  723 (747)
                      ..+.+.+      .+..++.++. +. +..++..++.+|.+++.+.+....+..
T Consensus       204 ~~l~~~g~~~~~~~l~~ll~~l~~~~-~~~~~~~a~~~L~nl~~~~~~~~~i~~  256 (369)
T 6HB2_D          204 MYFIEEQEYDGVVPISKLLVFTEKYD-AKVRREGVASTIKNSLFDSETHERLLK  256 (369)
T ss_dssp             HHHHSCCTTTCSCTHHHHGGGGGCTT-CHHHHHHHHHHHHHHTCSGGGHHHHHH
T ss_pred             HHHhhcccccCcccHHHHHHHhcccC-CHHHHHHHHHHHHHHhcCHHHHHHHhc
Confidence            6677766      4666666665 34 678899999999999988775544443


No 146
>5MFD_C YIIIM''6AII, Capsid decoration protein,pD_(KR)5; Designed armadillo repeat protein, peptide; HET: CA; 2.3A {synthetic construct}
Probab=96.84  E-value=1.8e-06  Score=81.45  Aligned_cols=114  Identities=25%  Similarity=0.284  Sum_probs=77.1  Template_Neff=13.300

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.+..++..++.++..+..........+
T Consensus        47 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  126 (328)
T 5MFD_C           47 ALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAV  126 (328)
T ss_dssp             CHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             cHHHHHHHhcCCCHHHHHHHHHHHHHHhcCcHHHHHHHhhcCHHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45566666777777888899999988876543333333344567777777777777888889999988876533333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++..+...
T Consensus       127 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  160 (328)
T 5MFD_C          127 IDAGALPALVQLLS-SPNEQILQEALWTLGNIASG  160 (328)
T ss_dssp             HHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHTTS
T ss_pred             HHCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcC
Confidence            33456667777775 45667777788888777653


No 147
>6SA7_B DARPin-Armadillo fusion C8long83; protein fusion, DARPin, Armadillo, shared; 3.3A {synthetic construct}
Probab=96.84  E-value=1.8e-06  Score=88.77  Aligned_cols=115  Identities=27%  Similarity=0.318  Sum_probs=78.7  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.+|..++.........+...++++.+..++.+.++.++..++.++..++.........+
T Consensus       384 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  463 (510)
T 6SA7_B          384 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAV  463 (510)
T ss_dssp             HHHHHHHHHTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCchHHHHH
Confidence            34445555555667778888888888865544433344445677888888887788889999999999985544433333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD  361 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~  361 (747)
                      ...++++.+..++. +.++.++..++.++..+....
T Consensus       464 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~  498 (510)
T 6SA7_B          464 KEAGALEKLEQLQS-HENEKIQKEAQEALEKLGSGG  498 (510)
T ss_dssp             HHTTHHHHHHHGGG-CSSHHHHHHHHHHHHHHTC--
T ss_pred             HHCCHHHHHHHHhh-ccchHHHHHHHHHHHHHhhcc
Confidence            34456777777776 556788888999888887643


No 148
>6S9O_F designed Armadillo repeat protein with; peptide binder, repeat protein, designed; HET: CA, EDO; 3.17A {synthetic construct}
Probab=96.77  E-value=2.5e-06  Score=81.50  Aligned_cols=115  Identities=28%  Similarity=0.317  Sum_probs=77.6  Template_Neff=13.100

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..++...+.....+...++++.+...+.+.+..++..++.++..++.........
T Consensus        46 ~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  125 (344)
T 6S9O_F           46 GALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALRNIASGGNEQIQA  125 (344)
T ss_dssp             TCHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHHHSCSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             ChHHHHHHHcCCCCHHHHHHHHHHHHHHhcCChhHHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCchHHHH
Confidence            34556666677777788889999999887654333333334456777777777777788888999998887643333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      +...++++.+...+. ..++.++..++.++..++..
T Consensus       126 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  160 (344)
T 6S9O_F          126 VIDAGALPALVQLLS-SPNEQILSSALGALSNIASG  160 (344)
T ss_dssp             HHHTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHHTS
T ss_pred             HHhCCHHHHHHHHhc-CCcHHHHHHHHHHHHHHHcC
Confidence            333456677777775 45667777888888877653


No 149
>1XM9_A plakophilin 1  Plakophilin-1; armadillo repeat, CELL ADHESION; 2.8A {Homo sapiens} SCOP: a.118.1.24
Probab=96.77  E-value=2.5e-06  Score=86.12  Aligned_cols=167  Identities=15%  Similarity=0.182  Sum_probs=108.5  Template_Neff=12.600

Q NP_000290.2     543 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL----------------QS  606 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL----------------~s  606 (747)
                      +++.++++.|+.++....++.++..++.+|.+++....      ....+. .++++.|+.++                ..
T Consensus        82 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~------~~~~~~-~~~~~~l~~~l~~~~~~~~~~~~~~~~~~  154 (457)
T 1XM9_A           82 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE------LKEELI-ADALPVLADRVIIPFSGWCDGNSNMSREV  154 (457)
T ss_dssp             HHHTTCHHHHHHHHTTCCCHHHHHHHHHHHHHHHTSSS------THHHHH-HHHHHHCCCCCCHHHHTCC---------C
T ss_pred             HHhcChHHHHHHHhhhCCCHHHHHHHHHHHHHHhCCHH------HHHHHH-cchHHHHHHHhccccCCCCCCCCCccccc
Confidence            45677888888888633566788889999999987422      123333 57888888888                56


Q NP_000290.2     607 GNSDVVRSGASLLSNMSRHPLL-HRVMG-NQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP-----------  673 (747)
Q Consensus       607 ~d~eVr~~AL~aLsnLa~~~e~-~~ll~-~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~-----------  673 (747)
                      .++.++..++++|.+++..... ..+.. .++++.++.++.........+..++..++.+|.+++...+           
T Consensus       155 ~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~  234 (457)
T 1XM9_A          155 VDPEVFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLE  234 (457)
T ss_dssp             CCHHHHHHHHHHHHHHTTSHHHHHHHTTSTTHHHHHHHHHHHHHHHTCTTCTTHHHHHHHHHHHTTTHHHHSCCHHHHHH
T ss_pred             CCHHHHHHHHHHHHHHccChHHHHHHHhcccHHHHHHHHHHHhhhcCcCCHHHHHHHHHHHHHHhcccccCCCcchhhhh
Confidence            6788899999999999976433 22332 3567777777764100000256788889999999886311           


Q NP_000290.2     674 ---------------------------------------QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       674 ---------------------------------------e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                                                             .....+...++++.++.++....+..++..++.+|.+++..
T Consensus       235 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~  314 (457)
T 1XM9_A          235 YNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTAS  314 (457)
T ss_dssp             HTC----------------------------CCCCCSSCCGGGGGGSHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTC
T ss_pred             hcccccccccccccccCcccchhccccccCCCCcccCCCchhHHhhchhHHHHHHHHhccCCCHHHHHHHHHHHHHHHhc
Confidence                                                   11122334456667777766532556677788888887765


Q NP_000290.2     715 KE  716 (747)
Q Consensus       715 ~~  716 (747)
                      .+
T Consensus       315 ~~  316 (457)
T 1XM9_A          315 KG  316 (457)
T ss_dssp             SS
T ss_pred             cc
Confidence            54


No 150
>4HXT_A De Novo Protein OR329; Structural Genomics, PSI-Biology, Protein Structure; 1.95A {artificial gene}
Probab=96.77  E-value=2.5e-06  Score=77.32  Aligned_cols=114  Identities=27%  Similarity=0.311  Sum_probs=76.9  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++.........+...++++.+...+.+.++.++..++.++..++...+.....+
T Consensus       129 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  208 (252)
T 4HXT_A          129 GVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPTSAIKAI  208 (252)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSBHHHHHHH
T ss_pred             HHHHHHHHhhCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            34555555666667788888888888876543333333344567777777777777888889999988886544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++.+++..
T Consensus       209 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~  242 (252)
T 4HXT_A          209 VDAGGVEVLQKLLT-STDSEVQKEAQRALENIKSG  242 (252)
T ss_dssp             HHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHHHT
T ss_pred             HHCCHHHHHHHHhc-CCCHHHHHHHHHHHHHHHcC
Confidence            33356777777776 45677888888888888764


No 151
>6SA6_A DARPin-Armadillo fusion A5; protein fusion, DARPin, Armadillo, shared; HET: EDO; 1.6A {synthetic construct}
Probab=96.73  E-value=3e-06  Score=84.23  Aligned_cols=132  Identities=23%  Similarity=0.240  Sum_probs=87.4  Template_Neff=12.400

Q NP_000290.2     248 PKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRR  327 (747)
Q Consensus       248 ~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~  327 (747)
                      ..++..+.+.+..++..++.++.+++.........+...++++.+..++.+.++.++..++.++.+++.........+..
T Consensus       160 ~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~  239 (397)
T 6SA6_A          160 AALVLKLNANDDQIIQEALWKLGNHASGGNLRIQWVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVID  239 (397)
T ss_dssp             HHHHHHTTCSCHHHHHHHHHHHHHHHTTTHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHH
T ss_pred             HHHHHHccCCCHHHHHHHHHHHHHHhhCCchHHHHHHHCCcHHHHHHHcCCCCHHHHHHHHHHHHHHhCCCHHHHHHHHH
Confidence            34445555567788889999999988755444444445567788888888777788889999999988654443334444


Q NP_000290.2     328 QNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       328 ~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      .++++.+..++. ..++.++..++.++.+++..... ...+.. ++++.|+.+|.
T Consensus       240 ~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  293 (397)
T 6SA6_A          240 AGALPALVQLLS-SPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLS  293 (397)
T ss_dssp             TTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             CCcHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCcHHHHHHHHhCChHHHHHHHhc
Confidence            567777888876 55677888888888888654222 222222 45555555543


No 152
>3NMZ_A APC variant protein, Rho guanine; protein-protein complex, armadillo repeats, CELL; 3.01A {Homo sapiens}
Probab=96.71  E-value=3.3e-06  Score=86.51  Aligned_cols=135  Identities=22%  Similarity=0.327  Sum_probs=88.0  Template_Neff=12.000

Q NP_000290.2     246 TIPKAVQYLSSQ-----------DEKYQAIGAYYIQHTCFQDESAKQQVYQ-LGGICKLVDLLRSPNQNVQQAAAGALRN  313 (747)
Q Consensus       246 iL~~Ll~lL~ss-----------d~eVr~sAL~aLsnLs~~~~~~~~~li~-~~IL~~Ll~lL~s~d~eVr~~AL~aLs~  313 (747)
                      +++.+..++...           +..++..++.+|.+++.........+.. .++++.+..++...+..++..++.++.+
T Consensus       190 ~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~a~~~L~~  269 (458)
T 3NMZ_A          190 GLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRN  269 (458)
T ss_pred             hHHHHHHHHhccccCCCCCCCCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHhCCcHHHHHHHhcCCCHHHHHHHHHHHHH
Confidence            445555555543           5678888999999988754433332333 4677888888877778889999999999


Q NP_000290.2     314 LVFRST-TNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST-DELKEELI--ADALPVLADRVI  380 (747)
Q Consensus       314 La~~~~-~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~-~~~~~~Lv--egiLe~Lv~LL~  380 (747)
                      ++.... .....+...++++.+..++....+..++..++.++.+++.. ......+.  .++++.|+.++.
T Consensus       270 l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  340 (458)
T 3NMZ_A          270 LSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLT  340 (458)
T ss_pred             HHCCCChhHHHHHHHCCHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCchhHHHHHHhcChHHHHHHHHc
Confidence            886543 22333444457777777775234567888889999998873 33333333  256666666654


No 153
>6HB1_A Protein HGH1; solenoid protein, Armadillo repeat, CHAPERONE; 2.33A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=96.61  E-value=5.3e-06  Score=85.37  Aligned_cols=93  Identities=22%  Similarity=0.297  Sum_probs=66.7  Template_Neff=10.100

Q NP_000290.2     287 GGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQ--NGIREAVSLLRR--TGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       287 ~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~--~IL~~Ll~lL~s--s~d~eVr~~AL~aLsnLas~~~  362 (747)
                      +.++.++.++...++.++..++.++.++.....  ...+...  +.++.|+.++..  ..++.++..++.+|.+++....
T Consensus         9 ~~i~~lv~lL~~~~~~v~~~a~~~L~~l~~~~~--~~~l~~~~~~~i~~Lv~ll~~~~~~~~~~~~~al~~L~~l~~~~~   86 (369)
T 6HB1_A            9 SQLNELVEFLHSPQPAVRQIAIDNLVGFSAGPT--SKVFKNDSYRPIKDIIKMIMDPEHGTRVIIQQGVTILVNLSEDKL   86 (369)
T ss_dssp             CCHHHHHHGGGCSCHHHHHHHHHHHGGGGSSGG--GGGGGHHHHHHHHHHHHHHHCTTTCCHHHHHHHHHHHHHHTTSHH
T ss_pred             hhHHHHHHHhcCCCHHHHHHHHHHHhHhcCCCC--chhhhcCCchHHHHHHHHHhCcccCcHHHHHHHHHHHHHHhCCHH
Confidence            456677777777777888899999988876543  2333333  478888888852  1356788899999999987655


Q NP_000290.2     363 LKEELI--A-DALPVLADRVII  381 (747)
Q Consensus       363 ~~~~Lv--e-giLe~Lv~LL~~  381 (747)
                      ....+.  + ++++.|+.++..
T Consensus        87 ~~~~l~~~~~g~i~~L~~ll~~  108 (369)
T 6HB1_A           87 VRNIILSDDKKFLKFLVWKIVD  108 (369)
T ss_dssp             HHHCCCCCSTHHHHHHHHHHHC
T ss_pred             HHHHHhhcChHHHHHHHHHHHc
Confidence            556666  5 888888888874


No 154
>6HB2_D Protein HGH1; solenoid protein, Armadillo repeat, CHAPERONE; HET: MSE; 2.7A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=96.61  E-value=5.3e-06  Score=85.37  Aligned_cols=93  Identities=22%  Similarity=0.297  Sum_probs=66.7  Template_Neff=10.100

Q NP_000290.2     287 GGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQ--NGIREAVSLLRR--TGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       287 ~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~--~IL~~Ll~lL~s--s~d~eVr~~AL~aLsnLas~~~  362 (747)
                      +.++.++.++...++.++..++.++.++.....  ...+...  +.++.|+.++..  ..++.++..++.+|.+++....
T Consensus         9 ~~i~~lv~lL~~~~~~v~~~a~~~L~~l~~~~~--~~~l~~~~~~~i~~Lv~ll~~~~~~~~~~~~~al~~L~~l~~~~~   86 (369)
T 6HB2_D            9 SQLNELVEFLHSPQPAVRQIAIDNLVGFSAGPT--SKVFKNDSYRPIKDIIKMIMDPEHGTRVIIQQGVTILVNLSEDKL   86 (369)
T ss_dssp             HHHHHHHGGGGCSCHHHHHHHHHHHGGGGSSGG--GGGGGHHHHHHHHHHHHHHHCTTTCCHHHHHHHHHHHHHHTTSHH
T ss_pred             hhHHHHHHHhcCCCHHHHHHHHHHHhHhcCCCC--chhhhcCCchHHHHHHHHHhCcccCcHHHHHHHHHHHHHHhCCHH
Confidence            456677777777777888899999988876543  2333333  478888888852  1356788899999999987655


Q NP_000290.2     363 LKEELI--A-DALPVLADRVII  381 (747)
Q Consensus       363 ~~~~Lv--e-giLe~Lv~LL~~  381 (747)
                      ....+.  + ++++.|+.++..
T Consensus        87 ~~~~l~~~~~g~i~~L~~ll~~  108 (369)
T 6HB2_D           87 VRNIILSDDKKFLKFLVWKIVD  108 (369)
T ss_dssp             HHHCCCCCCTHHHHHHHHHHSC
T ss_pred             HHHHHhhcChHHHHHHHHHHHc
Confidence            556666  5 888888888874


No 155
>2W3C_A GENERAL VESICULAR TRANSPORT FACTOR P115; MEMBRANE VESICLE TETHERING, ARMADILLO FOLD; HET: PEG; 2.22A {HOMO SAPIENS}
Probab=96.59  E-value=5.7e-06  Score=90.00  Aligned_cols=135  Identities=13%  Similarity=0.124  Sum_probs=95.4  Template_Neff=10.400

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDE-SAKQQVY-QLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~-~~~~~li-~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .++.++.++.+.+..++..++.+|..++...+ .....+. ..+.++.++.++.+.+..++..++.+|..++........
T Consensus        71 ~i~~L~~ll~~~~~~v~~~a~~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~~~~~~~~~~a~~~L~~l~~~~~~~~~  150 (577)
T 2W3C_A           71 NVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRSNGAIQK  150 (577)
T ss_dssp             HHHHHHHHTTCCCHHHHHHHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHHGGGGCSSHHHHHHHHHHHHHHHTTCHHHHH
T ss_pred             hHHHHHHHccCCCHHHHHHHHHHHHHHHHhchHHHHHHHHhCCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHH
Confidence            45566666766778889999999999987543 2222333 246788888888877788899999999999875444444


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGN----AEIQKQLTGLLWNLSSTDELKEEL-IA-DALPVLADRVII  381 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d----~eVr~~AL~aLsnLas~~~~~~~L-ve-giLe~Lv~LL~~  381 (747)
                      .+...+.++.|+.++. ...    ..++..++.+|.+++........+ .+ ++++.|+.+|..
T Consensus       151 ~~~~~g~~~~L~~ll~-~~~~~~~~~v~~~al~~L~~l~~~~~~~~~~~~~~~~i~~L~~lL~~  213 (577)
T 2W3C_A          151 IVAFENAFERLLDIIS-EEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEV  213 (577)
T ss_dssp             HHHHTTHHHHHHHHHH-HTTGGGSCHHHHHHHHHHHHHHTTCHHHHHHHHHTTCGGGGSGGGCC
T ss_pred             HHHcCCHHHHHHHHHH-HhCCCCCcHHHHHHHHHHHHHHccCHHHHHHHHhcChHHHHHHHHhc
Confidence            4444678888888886 322    257788899999998765433333 34 788889888875


No 156
>4XZR_B Heh1-NLS, Kap60; karyopherins  nuclear import ; 2.25A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=96.58  E-value=5.2e-06  Score=81.38  Aligned_cols=114  Identities=19%  Similarity=0.154  Sum_probs=76.5  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.+..++..++.++..++..........
T Consensus       172 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  251 (423)
T 4XZR_B          172 ALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVV  251 (423)
T ss_dssp             GHHHHHHHTTCSCHHHHHHHHHHHHHHTSSSHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHhcCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666677788888888888876544333334444567777777777777888889999988876543332223


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++..++..
T Consensus       252 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  285 (423)
T 4XZR_B          252 INAGVLPALRLLLS-SPKENIKKEACWTISNITAG  285 (423)
T ss_dssp             HHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHTTS
T ss_pred             HHcChHHHHHHHhc-CCCHHHHHHHHHHHHHHhcC
Confidence            33356667777775 45667777888888877764


No 157
>3TT9_A Plakophilin-2; CELL ADHESION; HET: GOL; 1.55A {Homo sapiens}
Probab=96.56  E-value=6e-06  Score=75.59  Aligned_cols=136  Identities=22%  Similarity=0.238  Sum_probs=88.7  Template_Neff=12.300

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+..++.+.+..++..++.+|.+++.........+...+.++.++.++. ..+..++..++.++.+++... .....
T Consensus        53 ~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~-~~~~~  131 (233)
T 3TT9_A           53 GILKLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSND-KLKNL  131 (233)
T ss_dssp             HHHHHHHGGGCCCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHHTSG-GGHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCCcHHHHHHHcccHHHHHHHHhhCCCHHHHHHHHHHHHHHccCH-HHHHH
Confidence            4556666676667788889999999988644444444555577788888887 556778888999999987643 22233


Q NP_000290.2     325 TRRQNGIREAVSLLRRT--------------GNAEIQKQLTGLLWNLSS-TDELKEELIA-DA-LPVLADRVIIP  382 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss--------------~d~eVr~~AL~aLsnLas-~~~~~~~Lve-gi-Le~Lv~LL~~~  382 (747)
                      +...+++..+..++...              .+..++..++.++.+++. .......+.. +. ++.|+.++...
T Consensus       132 ~~~~~~~~~l~~ll~~~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~  206 (233)
T 3TT9_A          132 MITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGT  206 (233)
T ss_dssp             HHHHHHHHHCCCCCHHHHCCCGGGCCCCCTTCCHHHHHHHHHHHHHHTTSCHHHHHHHHTSTTHHHHHHHHHHHH
T ss_pred             hhhhcHHHHHHHHHhhccCCCCCCCCcccCCCcHHHHHHHHHHHHHHHhcCHHHHHHHHHcccHHHHHHHHHHcc
Confidence            33334455555554311              135677888899999887 4444444444 55 78888877653


No 158
>6HB3_B Protein HGH1; solenoid protein, Armadillo repeat, CHAPERONE; 3.0A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=96.56  E-value=6.6e-06  Score=84.61  Aligned_cols=93  Identities=22%  Similarity=0.297  Sum_probs=66.7  Template_Neff=10.100

Q NP_000290.2     287 GGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQ--NGIREAVSLLRR--TGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       287 ~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~--~IL~~Ll~lL~s--s~d~eVr~~AL~aLsnLas~~~  362 (747)
                      +.++.++.++...+..++..++.++.++.....  ...+...  +.++.|+.++..  ..+..++..++.+|.+++....
T Consensus         9 ~~~~~lv~lL~~~~~~v~~~a~~~L~~l~~~~~--~~~l~~~~~~~i~~Lv~ll~~~~~~~~~~~~~al~~L~~l~~~~~   86 (369)
T 6HB3_B            9 SQLNELVEFLHSPQPAVRQIAIDNLVGFSAGPT--SKVFKNDSYRPIKDIIKMIMDPEHGTRVIIQQGVTILVNLSEDKL   86 (369)
T ss_pred             CcHHHHHHHccCCCHHHHHHHHHHHHHHcCChh--HHHHHHhCCCcHHHHHHHHhCCCCCCHHHHHHHHHHHHHHcCCHH
Confidence            456677777776677888899999988876543  2333333  478888888852  1356788899999999987655


Q NP_000290.2     363 LKEELI--A-DALPVLADRVII  381 (747)
Q Consensus       363 ~~~~Lv--e-giLe~Lv~LL~~  381 (747)
                      ....+.  . ++++.|+.+|..
T Consensus        87 ~~~~l~~~~~g~i~~L~~ll~~  108 (369)
T 6HB3_B           87 VRNIILSDDKKFLKFLVWKIVD  108 (369)
T ss_pred             HHHHHHhccCCcHHHHHHHhcC
Confidence            556666  5 888888888874


No 159
>6SA8_A ring-like DARPin-Armadillo fusion H83_D01, LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG; protein fusion, DARPin, Armadillo, shared; 2.4A {synthetic construct}
Probab=96.54  E-value=6.4e-06  Score=88.93  Aligned_cols=322  Identities=20%  Similarity=0.248  Sum_probs=204.5  Template_Neff=11.900

Q NP_000290.2     286 LGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELK  364 (747)
Q Consensus       286 ~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~  364 (747)
                      ...++.+...+...+..++..++.+|..++.........+...++++.+...+. ..++.++..++.++..++... ...
T Consensus       177 ~~~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~  255 (671)
T 6SA8_A          177 KKILKDLVKKLSSPNENELQNALWTLGNIASGGNEQIQAVIDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQI  255 (671)
T ss_dssp             HHHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHTTSCHHHH
T ss_pred             HHHHHHHHHhcCCCCHHHHHHHHHHHHHHHcCCcHHHHHHHHcChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCChHHH
Confidence            355667777777777778888888888887654333333444567777888886 557788999999999988743 222


Q NP_000290.2     365 EELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQT  443 (747)
Q Consensus       365 ~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  443 (747)
                      ..+.. ++++.|+.++..                .++++-..+..+|..-.         ..           ....+..
T Consensus       256 ~~~~~~~~~~~l~~~l~~----------------~~~~v~~~a~~~L~~l~---------~~-----------~~~~~~~  299 (671)
T 6SA8_A          256 QAVIDAGALPALVQLLSS----------------PNEQILQEALWALSNIA---------SG-----------GNEQIQA  299 (671)
T ss_dssp             HHHHHTTCHHHHHHHTTC----------------SCHHHHHHHHHHHHHHT---------TS-----------CHHHHHH
T ss_pred             HHHHHcCHHHHHHHHhcC----------------CCHHHHHHHHHHHHHHH---------cC-----------CcHHHHH
Confidence            33333 677777777753                13444444444443211         00           0001111


Q NP_000290.2     444 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMN  523 (747)
Q Consensus       444 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  523 (747)
                      . -..++++.|+..++.      .+..-...+...|.++....                                     
T Consensus       300 ~-~~~~~~~~L~~~l~~------~~~~v~~~a~~~L~~l~~~~-------------------------------------  335 (671)
T 6SA8_A          300 V-IDAGALPALVQLLSS------PNEQILQEALWALSNIASGG-------------------------------------  335 (671)
T ss_dssp             H-HHTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHTTSC-------------------------------------
T ss_pred             H-HHhChHHHHHHHhcC------CcHHHHHHHHHHHHHHhcCC-------------------------------------
Confidence            1 113455555544431      11112222333333332110                                     


Q NP_000290.2     524 NNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARL  603 (747)
Q Consensus       524 ~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~L  603 (747)
                                   ......+.+.++++.|+.++. ..++.++..++.+|.+++...+.     ....+...++++.|+.+
T Consensus       336 -------------~~~~~~~~~~~~l~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~  396 (671)
T 6SA8_A          336 -------------NEQIQAVIDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNE-----QIQAVIDAGALPALVQL  396 (671)
T ss_dssp             -------------HHHHHHHHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHG
T ss_pred             -------------cHHHHHHHhcChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCcH-----HHHHHHHcCcHHHHHHH
Confidence                         001112345667888888887 46778888999999999874332     23333456788899999


Q NP_000290.2     604 LQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFS  681 (747)
Q Consensus       604 L~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve  681 (747)
                      +.+.++.++..++.+|.+++... .. ......++++.|+.++.+      .++.++..++.+|.+++...+.....+.+
T Consensus       397 l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~L~~~l~~------~~~~v~~~a~~~L~~l~~~~~~~~~~~~~  470 (671)
T 6SA8_A          397 LSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSS------PNEQILQEALWALSNIASGGNEQIQAVID  470 (671)
T ss_dssp             GGCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHGGGC------SCHHHHHHHHHHHHHHHTSCHHHHHHHHH
T ss_pred             hcCCCHHHHHHHHHHHHhhcCCCHHHHHHHHhcCcHHHHHHHcCC------CCHHHHHHHHHHHHHHHcCChHHHHHHHh
Confidence            98888899999999999998762 22 233445678888888876      36788999999999999765544455556


Q NP_000290.2     682 SSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       682 ~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      .++++.|+.++.+. ++.++..++.+|.+++..
T Consensus       471 ~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~~  502 (671)
T 6SA8_A          471 AGALPALVQLLSSP-NEQIQDEAEKTLLNIANG  502 (671)
T ss_dssp             TTHHHHHHHHTTCS-CHHHHHHHHHHHHHHHTS
T ss_pred             cCcHHHHHHHhhCC-CHHHHHHHHHHHHHHHcC
Confidence            67788888888876 788899999999998854


No 160
>1EE4_A KARYOPHERIN ALPHA; ARM repeat, TRANSPORT PROTEIN; 2.1A {Saccharomyces cerevisiae} SCOP: a.118.1.1
Probab=96.51  E-value=6.8e-06  Score=80.51  Aligned_cols=114  Identities=22%  Similarity=0.183  Sum_probs=77.4  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..............++++.+...+.+.++.++..++.++..++...+.....+
T Consensus       214 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  293 (423)
T 1EE4_A          214 IPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAV  293 (423)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHhcCCCcchhHHHHHHHHHHHhCChHHHHHHHHcChHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            44556666666677888889999988876543333333334667777777777777888899999988876544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++..++..
T Consensus       294 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  327 (423)
T 1EE4_A          294 IDANLIPPLVKLLE-VAEDKTKKEACWAISNASSG  327 (423)
T ss_dssp             HHTTCHHHHHHHHH-HSCHHHHHHHHHHHHHHHGG
T ss_pred             HHCCcHHHHHHHHh-cCCHHHHHHHHHHHHHHHcC
Confidence            34456677777775 55667788888888887764


No 161
>1EE4_B KARYOPHERIN ALPHA; ARM repeat, TRANSPORT PROTEIN; 2.1A {Saccharomyces cerevisiae} SCOP: a.118.1.1
Probab=96.51  E-value=6.8e-06  Score=80.51  Aligned_cols=114  Identities=22%  Similarity=0.183  Sum_probs=77.4  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..............++++.+...+.+.++.++..++.++..++...+.....+
T Consensus       214 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  293 (423)
T 1EE4_B          214 IPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAV  293 (423)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             HHHHHHHHhcCCCcchhHHHHHHHHHHHhCChHHHHHHHHcChHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            44556666666677888889999988876543333333334667777777777777888899999988876544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++..++..
T Consensus       294 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  327 (423)
T 1EE4_B          294 IDANLIPPLVKLLE-VAEDKTKKEACWAISNASSG  327 (423)
T ss_dssp             HHTTCHHHHHHHHH-HSCHHHHHHHHHHHHHHHGG
T ss_pred             HHCCcHHHHHHHHh-cCCHHHHHHHHHHHHHHHcC
Confidence            34456677777775 55667788888888887764


No 162
>5KC2_B Phosphatidylinositol 3-kinase VPS34 (E.C.2.7.1.137), Serine/threonine-protein; autophagy, phosphatidylinositol 3-kinase (PtdIns3K), endocytosis; 28.0A {Saccharomyces cerevisiae}
Probab=96.45  E-value=9.9e-06  Score=98.55  Aligned_cols=150  Identities=9%  Similarity=0.041  Sum_probs=112.4  Template_Neff=9.500

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++++.|+.+|. +.++.++..|+.+|..++....       ...+.+.. ++.|+.+|.+.++.++..++.+|++|+..
T Consensus       618 ~~~l~~L~~~l~-d~~~~vR~~a~~al~~l~~~~~-------~~~~~~~~-lp~L~~lL~d~~~~vr~~al~aL~~L~~~  688 (1454)
T 5KC2_B          618 DIILSHLITYLN-DKDPALRVSLIQTISGISILLG-------TVTLEQYI-LPLLIQTITDSEELVVISVLQSLKSLFKT  688 (1454)
T ss_pred             hhhHHHHHHHcc-CCCHHHHHHHHHHHHHHHHhhH-------HHHHHHcC-HHHHHHHhcCCCHHHHHHHHHHHHHHhhC
Confidence            346788889998 5888999999999999986431       22223333 89999999988889999999999999876


Q NP_000290.2     626 P-LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       626 ~-e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      . .....+.. +++.+..++.+      .++.++..++.+|..|+.....  .... ..+++.|+.+|.+. +..+++.|
T Consensus       689 ~~~~~~~~~~-~l~~l~~~l~~------~~~~vr~~a~~~L~~l~~~~~~--~~~~-~~~~~~L~~~L~d~-~~~vr~~a  757 (1454)
T 5KC2_B          689 GLIRKKYYID-ISKTTSPLLLH------PNNWIRQFTLMIIIEIINKLSK--AEVY-CILYPIIRPFFEFD-VEFNFKSM  757 (1454)
T ss_pred             CHHHHHHHHH-HHHHHHHHHCC------CCHHHHHHHHHHHHHHhcCCCC--HHHH-cChHHHHHHHhcCC-CHHHHHHH
Confidence            3 22222222 66777777766      3788999999999999875321  1122 45788899999877 88999999


Q NP_000290.2     705 RLLLSDMWSSK  715 (747)
Q Consensus       705 L~aLsnL~~~~  715 (747)
                      +.+|..++..+
T Consensus       758 ~~~L~~~~~~~  768 (1454)
T 5KC2_B          758 ISCCKQPVSRS  768 (1454)
T ss_pred             HHHHHHHhhcc
Confidence            99999988765


No 163
>4B18_A IMPORTIN SUBUNIT ALPHA-1, TELOMERASE REVERSE; TRANSPORT PROTEIN - PEPTIDE COMPLEX; 2.52A {HOMO SAPIENS}
Probab=96.44  E-value=8.9e-06  Score=80.74  Aligned_cols=366  Identities=18%  Similarity=0.167  Sum_probs=217.7  Template_Neff=13.000

Q NP_000290.2     245 LTIPKAVQYLSS-QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~s-sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .+++.+...+.. .++.++..++.++..++.........+...++++.+...+.+.+..++..++.++..++........
T Consensus        61 ~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~  140 (447)
T 4B18_A           61 GVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRD  140 (447)
T ss_dssp             THHHHHHHHTTCTTCHHHHHHHHHHHHHHTSSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHH
T ss_pred             cHHHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCcHHHHHHHHcChHHHHHHHhhCCCHHHHHHHHHHHHHHHccChhHHH
Confidence            345556666655 5677888889999888765433333333456777888888777788889999999988765443333


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVIIPFSGWCDGNSNMSREVVDPE  401 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~  401 (747)
                      .+...++++.+...+....++.++..++.++..++...........  ++++.+..++..                .+++
T Consensus       141 ~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~  204 (447)
T 4B18_A          141 YVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFV----------------SDTD  204 (447)
T ss_dssp             HHHHTTCHHHHHHGGGCTTCHHHHHHHHHHHHHHHCCSSSCCCHHHHGGGHHHHHHHTTS----------------CCHH
T ss_pred             HHHHCCcHHHHHHHhhcCCChhHHHHHHHHHHHHhcCCCCCCcccccccHHHHHHHHhhC----------------CCHH
Confidence            3334456777777775333457888888999888765432222211  455556655532                1334


Q NP_000290.2     402 VFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHN  481 (747)
Q Consensus       402 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  481 (747)
                      +...+..++..-...      -+              ...+.+. -.+++..|...+..      .+..-.+.+...|.+
T Consensus       205 ~~~~a~~~l~~l~~~------~~--------------~~~~~~~-~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~  257 (447)
T 4B18_A          205 VLADACWALSYLSDG------PN--------------DKIQAVI-DAGVCRRLVELLMH------NDYKVVSPALRAVGN  257 (447)
T ss_dssp             HHHHHHHHHHHHTSS------SH--------------HHHHHHH-HTTCHHHHHHHTTC------SCHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhcC------CH--------------HHHHHHH-HCCHHHHHHHHHcC------CCHHHHHHHHHHHHH
Confidence            444444333221100      00              0000000 12333333333321      111112222222322


Q NP_000290.2     482 LSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKK  561 (747)
Q Consensus       482 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d  561 (747)
                      +....                                                  ......+.+.++++.|+.++. +.+
T Consensus       258 l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~  286 (447)
T 4B18_A          258 IVTGD--------------------------------------------------DIQTQVILNCSALQSLLHLLS-SPK  286 (447)
T ss_dssp             HTTSC--------------------------------------------------HHHHHHHHHTTHHHHHHHHTT-CSS
T ss_pred             HhcCC--------------------------------------------------hHHHHHHhhcchHHHHHHHhc-CCC
Confidence            22110                                                  000112234567888888887 467


Q NP_000290.2     562 DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH--PLL-HRVMGNQVFP  638 (747)
Q Consensus       562 ~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~--~e~-~~ll~~giI~  638 (747)
                      +.++..++.+|.+++.....     ....+...++++.+..++.+.++.++..++.+|.+++..  ... ..+...++++
T Consensus       287 ~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~  361 (447)
T 4B18_A          287 ESIKKEACWTISNITAGNRA-----QIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIK  361 (447)
T ss_dssp             HHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHTCHH
T ss_pred             HHHHHHHHHHHHHHhcCCHH-----HHHHHHhCChHHHHHHHHhcCCHHHHHHHHHHHHHHhccCCHHHHHHHHHCCcHH
Confidence            78888999999999875332     223334567888899998888888999999999999875  222 2334446778


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK-----------QYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~-----------~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .+..++.+      .++.++..++.+|.+++...+....           .+.+.++++.+..++.+. ++.++..++.+
T Consensus       362 ~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~~-~~~v~~~a~~~  434 (447)
T 4B18_A          362 PLCDLLTV------MDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQSHE-NQEIYQKAFDL  434 (447)
T ss_dssp             HHHHGGGS------SCHHHHHHHHHHHHHHHHHHHHHHHHSSCCSCHHHHHHHHTTHHHHHHHGGGSS-CHHHHHHHHHH
T ss_pred             HHHHHhhC------CCHHHHHHHHHHHHHHHHHhHHHHhhCCCCCCHHHHHHHHhccHHHHHHHHhCC-CHHHHHHHHHH
Confidence            88888776      3678889999999999875332221           233445677777777666 77889999999


Q NP_000290.2     708 LSDMWSSKE  716 (747)
Q Consensus       708 LsnL~~~~~  716 (747)
                      +.++....+
T Consensus       435 l~~l~~~~~  443 (447)
T 4B18_A          435 IEHYFGTED  443 (447)
T ss_dssp             HHHHCC---
T ss_pred             HHHHhcCcc
Confidence            988876543


No 164
>1JDH_A BETA-CATENIN, hTcf-4; BETA-CATENIN, TCF4, PROTEIN-PROTEIN COMPLEX, TRANSCRIPTION; 1.9A {Homo sapiens} SCOP: a.118.1.1
Probab=96.44  E-value=9e-06  Score=82.47  Aligned_cols=363  Identities=19%  Similarity=0.190  Sum_probs=216.7  Template_Neff=13.100

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP-NQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~-d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .+++.+...+.+.++.++..++.++..+....+.....+...++++.+...+... +..++..++.++..+..... ...
T Consensus       143 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~-~~~  221 (529)
T 1JDH_A          143 GGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSS-NKP  221 (529)
T ss_dssp             THHHHHHHGGGCCCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTSTT-HHH
T ss_pred             ChHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCChhHHHHHHHccCCcHHHHHHHHHHHHHHhcCCc-cHH
Confidence            3455666667667788888999999988754444333444455777777777654 56778888888888875432 222


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      .+...++++.+...+. ..++.++..++.++..++....... ...++++.+..++..                -++++.
T Consensus       222 ~~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~-~~~~~~~~l~~~l~~----------------~~~~~~  283 (529)
T 1JDH_A          222 AIVEAGGMQALGLHLT-DPSQRLVQNCLWTLRNLSDAATKQE-GMEGLLGTLVQLLGS----------------DDINVV  283 (529)
T ss_dssp             HHHHTTHHHHHHTTTT-SSCHHHHHHHHHHHHHHHTTCTTCS-CCHHHHHHHHHHTTC----------------SCHHHH
T ss_pred             HHHHCCHHHHHHHHcc-CCCHHHHHHHHHHHHHHcchhhhHH-HHchHHHHHHHHhCC----------------CCHHHH
Confidence            3333456777777776 4566788888888888876432211 112455556655541                123333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-...      .+.              .+..+ .-.+.++.++..+..    ..-+..-.+.+...|.++.
T Consensus       284 ~~a~~~l~~l~~~------~~~--------------~~~~~-~~~~~~~~l~~~l~~----~~~~~~~~~~a~~~l~~l~  338 (529)
T 1JDH_A          284 TCAAGILSNLTCN------NYK--------------NKMMV-CQVGGIEALVRTVLR----AGDREDITEPAICALRHLT  338 (529)
T ss_dssp             HHHHHHHHHHTTT------CHH--------------HHHHH-HHTTHHHHHHHHHHH----HTTCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHhcC------CHH--------------HHHHH-HHcCHHHHHHHHHHh----cCCChHhHHHHHHHHHHHh
Confidence            3333333221100      000              00000 012233333332211    0111222333444444443


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      .......                                               .....+...++++.++.++....++.
T Consensus       339 ~~~~~~~-----------------------------------------------~~~~~~~~~~~~~~l~~~l~~~~~~~  371 (529)
T 1JDH_A          339 SRHQEAE-----------------------------------------------MAQNAVRLHYGLPVVVKLLHPPSHWP  371 (529)
T ss_dssp             SSSTTHH-----------------------------------------------HHHHHHHHTTCHHHHHHTTSTTCCHH
T ss_pred             cCcccHH-----------------------------------------------HHHHHHHhcccHHHHHHHHCCCCCHH
Confidence            2211000                                               00111234566778888887323667


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN----------------------SDVVRSGASLLSN  621 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d----------------------~eVr~~AL~aLsn  621 (747)
                      ++..++.+|.+++....      ....+...++++.|..++.+.+                      +.++..++.+|.+
T Consensus       372 ~~~~a~~~l~~l~~~~~------~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~  445 (529)
T 1JDH_A          372 LIKATVGLIRNLALCPA------NHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHI  445 (529)
T ss_dssp             HHHHHHHHHHHHTTSGG------GHHHHHHTTHHHHHHHHHHHHHHHHC-----------CBTTBCHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhcChh------hhHHHHhcCHHHHHHHHHHhcChhHHHHHhccCcchhHhccCCHHHHHHHHHHHHHH
Confidence            88889999999887532      1333345678888888887654                      6788889999999


Q NP_000290.2     622 MSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       622 La~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      ++..... ..+...++++.+..++.+      .++.++..++.+|.+++.. +.....+...++++.|..++.+. ++.+
T Consensus       446 l~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~-~~~~~~~~~~~~~~~l~~~l~~~-~~~v  517 (529)
T 1JDH_A          446 LARDVHNRIVIRGLNTIPLFVQLLYS------PIENIQRVAAGVLCELAQD-KEAAEAIEAEGATAPLTELLHSR-NEGV  517 (529)
T ss_dssp             HTTSHHHHHHHHHTTCHHHHHHGGGC------SCHHHHHHHHHHHHHHTTS-HHHHHHHHHTTCHHHHHHGGGCS-SHHH
T ss_pred             HhcCccchHHHHhcCcHHHHHHHhcC------CCHHHHHHHHHHHHHHhcC-HHHHHHHHHcCcHHHHHHHHhcC-CHHH
Confidence            9876433 233445677888888876      3678899999999999875 44455555667888899988876 7889


Q NP_000290.2     701 AEAARLLLSDMW  712 (747)
Q Consensus       701 r~aAL~aLsnL~  712 (747)
                      +..++.+|.+++
T Consensus       518 ~~~a~~~L~~l~  529 (529)
T 1JDH_A          518 ATYAAAVLFRMS  529 (529)
T ss_dssp             HHHHHHHHHHHC
T ss_pred             HHHHHHHHHhcC
Confidence            999999888763


No 165
>5MFI_B YIII(Dq.V2)4CqI, (KR)4; Designed armadillo repeat protein, peptide; 1.45A {synthetic construct}
Probab=96.43  E-value=9.2e-06  Score=73.31  Aligned_cols=135  Identities=19%  Similarity=0.216  Sum_probs=90.0  Template_Neff=13.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.+..++..++.++.++....+.....+...++++.+...+.+.+..++..++.++..++.........
T Consensus        88 ~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~  167 (243)
T 5MFI_B           88 GALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQK  167 (243)
T ss_dssp             TCHHHHHHHTSSSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHTTTSSCHHHHHHHHHHHHHHHTSCHHHHHH
T ss_pred             CcHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            34555666666667778888999999887644443334444567777888887777788888999998888644433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ....++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus       168 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  224 (243)
T 5MFI_B          168 LIEAGALSPLVKLLD-DASEEVIQEAVWAIANIASGNNEQIQKLEEAGAEPALEKLQS  224 (243)
T ss_dssp             HHHTTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHGGG
T ss_pred             HHHCCcHHHHHHHcc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHhc
Confidence            334456777777776 5567888889999999886332 2222333 56666666654


No 166
>5MFJ_B YIII(Dq.V2)4CqI, (KR)5; Designed armadillo repeat protein, peptide; 1.53A {synthetic construct}
Probab=96.43  E-value=9.2e-06  Score=73.31  Aligned_cols=135  Identities=19%  Similarity=0.216  Sum_probs=90.0  Template_Neff=13.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.+..++..++.++.++....+.....+...++++.+...+.+.+..++..++.++..++.........
T Consensus        88 ~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~  167 (243)
T 5MFJ_B           88 GALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQK  167 (243)
T ss_dssp             TCHHHHHHHHHHSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHTTTSSCHHHHHHHHHHHHHHHTSCHHHHHH
T ss_pred             CcHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            34555666666667778888999999887644443334444567777888887777788888999998888644433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ....++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus       168 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  224 (243)
T 5MFJ_B          168 LIEAGALSPLVKLLD-DASEEVIQEAVWAIANIASGNNEQIQKLEEAGAEPALEKLQS  224 (243)
T ss_dssp             HHHTTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHTSS
T ss_pred             HHHCCcHHHHHHHcc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHhc
Confidence            334456777777776 5567888889999999886332 2222333 56666666654


No 167
>4MFU_A Beta-catenin-like protein 1; ARM repeats, GENE REGULATION; 2.744A {Homo sapiens}
Probab=96.43  E-value=1.1e-05  Score=87.33  Aligned_cols=182  Identities=12%  Similarity=0.061  Sum_probs=127.6  Template_Neff=8.700

Q NP_000290.2     539 GSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLM----SSGMSQLIGLKEKGLPQIARLLQS------GN  608 (747)
Q Consensus       539 ~~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~----s~~~~~~llie~giI~~Ll~LL~s------~d  608 (747)
                      ....+++.|+++.|+.+|. +++..+...++.+|.+++......    ........+.+.++++.|+.+|..      .+
T Consensus        60 ~~~~lv~~g~i~~Lv~LL~-~~n~~i~~~a~~~L~~Lt~~~~~~~~~~~~~~~~~~l~~~g~l~~Lv~~L~~~~e~~~~d  138 (490)
T 4MFU_A           60 LYHLLVELNAVQSLLGLLG-HDNTDVSIAVVDLLQELTDIDTLHESEEGAEVLIDALVDGQVVALLVQNLERLDESVKEE  138 (490)
T ss_dssp             CTHHHHHTTHHHHHHHHTS-CSSHHHHHHHHHHHHHHHHGGGSSCCCHHHHHHHHHHHHTTHHHHHHHHHHHCCTTCHHH
T ss_pred             HHHHHHHCChHHHHHHHhC-CCCHHHHHHHHHHHHHHcCcccccCChhhHHHHHHHHHhCCHHHHHHHHHHhccccccch
Confidence            3455678899999999998 466778888999999998643200    000013344577889999998875      55


Q NP_000290.2     609 SDVVRSGASLLSNMSRH-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLN  686 (747)
Q Consensus       609 ~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~  686 (747)
                      ...+..++.+|.+|+.. +.. ..+...++++.|+.++....    ....++..++.+|.+|+..++..+..+.+.++++
T Consensus       139 ~~~~~~al~~L~nL~~~~~~~~~~i~~~~~l~~Ll~~L~~~~----~~~~~k~~a~~~L~~L~~~~~~~~~~l~~~g~i~  214 (490)
T 4MFU_A          139 ADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKRLKAKM----PFDANKLYCSEVLAILLQDNDENRELLGELDGID  214 (490)
T ss_dssp             HHHHHHHHHHHHHHHHHSTTHHHHHCCCCCHHHHHHHHHCCS----CCCHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHH
T ss_pred             HHHHHHHHHHHHHHhccCHHHHHHHHHCCHHHHHHHHHHcCC----CCHHHHHHHHHHHHHHHcCCHHHHHHHHhCchHH
Confidence            67888999999999976 333 33445678888988887620    1367788999999999986566667777778899


Q NP_000290.2     687 NIINLCRS-----SA---SPKAAEAARLLLSDMWSSKELQGVLRQQG  725 (747)
Q Consensus       687 ~Ll~LL~s-----~~---d~eVr~aAL~aLsnL~~~~~~~~~~~~~~  725 (747)
                      .|+.++..     +.   .......++.+|.+++...+.+..+.+.|
T Consensus       215 ~Ll~lL~~~~~~d~~~~~~~e~~en~~~aL~~L~~~~~~~~~f~~~~  261 (490)
T 4MFU_A          215 VLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGE  261 (490)
T ss_dssp             HHHHHHHTTSSSCCSSHHHHHHHHHHHHHHHHHHHSTHHHHHHHHTT
T ss_pred             HHHHHHHhhhhcCCCCHHHHHHHHHHHHHHHHHhCCHHHHHHHHHCC
Confidence            99998851     11   12344556889999887776655554443


No 168
>5AEI_B DESIGNED ARMADILLO REPEAT PROTEIN YIIIM5AII; DE NOVO PROTEIN, PROTEIN-PEPTIDE COMPLEX; HET: CA, ACT; 1.83A {SYNTHETIC CONSTRUCT}
Probab=96.41  E-value=1e-05  Score=74.57  Aligned_cols=134  Identities=26%  Similarity=0.306  Sum_probs=85.5  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.+..++..++.++..++..........
T Consensus        89 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  168 (286)
T 5AEI_B           89 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV  168 (286)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHhCCHHHHHHHHccCCCHHHHHHHHHHHHHHHcCChHHHHHH
Confidence            44556666666677788888999888876533333333344567777777777777888889999988876543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus       169 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  224 (286)
T 5AEI_B          169 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLS  224 (286)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHcChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHcc
Confidence            33456677777775 4566778888888888876422 2222222 45565655554


No 169
>4PLS_B Arm00010; PEPTIDE BINDING PROTEIN, designed armadillo; HET: CA; 2.35A {synthetic construct}
Probab=96.39  E-value=1.1e-05  Score=74.12  Aligned_cols=111  Identities=25%  Similarity=0.289  Sum_probs=73.2  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..++...+.....+...++++.+...+.+.++.++..++.++..++...+.....+
T Consensus       170 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  249 (281)
T 4PLS_B          170 ALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAV  249 (281)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCcHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHccCCCHHHHHHHHHHHHHHHcCChhHHHHH
Confidence            45556666666677888889999988876544333333444577777787877777888899999998885544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNL  357 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnL  357 (747)
                      ...++++.+...+. ..++.++..++.++..+
T Consensus       250 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l  280 (281)
T 4PLS_B          250 KEAGAEPALEQLQS-SPNEKIQKEAQEALEKI  280 (281)
T ss_dssp             HTTTHHHHHHTTTS-CSCHHHHHHHHHHHHHC
T ss_pred             HHCChHHHHHHHhc-CCCHHHHHHHHHHHHhh
Confidence            33356666666665 45666777777666554


No 170
>4HM9_A Beta-catenin-like protein 1; all alpha-helical, armadillo repeats, PROTEIN; 3.1001A {Homo sapiens}
Probab=96.38  E-value=1.4e-05  Score=88.57  Aligned_cols=181  Identities=12%  Similarity=0.075  Sum_probs=128.1  Template_Neff=8.100

Q NP_000290.2     539 GSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSS---G--MSQLIGLKEKGLPQIARLLQS------G  607 (747)
Q Consensus       539 ~~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~---~--~~~~llie~giI~~Ll~LL~s------~  607 (747)
                      ....+++.|+++.|+.+|. +.+..++..++.+|.+|+..... ..   .  .....+.+.++++.|+.+|..      .
T Consensus       138 ~~~~lv~~g~i~~Lv~LL~-~~n~di~~~a~~~L~~Lt~~~~~-~~~~~~~~~l~~~l~e~g~l~~Lv~~L~~l~e~~~~  215 (568)
T 4HM9_A          138 LYHLLVELNAVQSLLGLLG-HDNTDVSIAVVDLLQELTDIDTL-HESEEGAEVLIDALVDGQVVALLVQNLERLDESVKE  215 (568)
T ss_dssp             GHHHHHHTTHHHHHHHGGG-CSSHHHHHHHHHHHHHHTCHHHH-TTCHHHHHHHHHHHHHTTHHHHHHHHHTTCCTTSHH
T ss_pred             HHHHHHHCChHHHHHHHhC-CCCHHHHHHHHHHHHHHhCCccc-cCChhhHHHHHHHHHhCCHHHHHHHHHhcccccccc
Confidence            4455678899999999998 46678888999999999864320 00   0  013344567889999998876      5


Q NP_000290.2     608 NSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSML  685 (747)
Q Consensus       608 d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL  685 (747)
                      +...+..++.+|.+|+.. +.. ..+...++++.|+.++....    .....+..|+.+|.+|+..++..+..+.+.+++
T Consensus       216 d~~~~~~al~iL~nL~~~~~~~~~~i~~~g~l~~Ll~lL~~~~----~~~~~k~~AaeiL~~L~~~~~~~r~~l~~~g~I  291 (568)
T 4HM9_A          216 EADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKRLKAKM----PFDANKLYCSEVLAILLQDNDENRELLGELDGI  291 (568)
T ss_dssp             HHHHHHHHHHHHHHHHHHCGGGHHHHCCCCCHHHHHHHHHSSC----CCCHHHHHHHHHHHHHHTTCHHHHHHHHHTTHH
T ss_pred             hHHHHHHHHHHHHHHhccCHHHHHHHHHCCHHHHHHHHHHcCC----CCHHHHHHHHHHHHHHHcCCHHHHHHHHhCchH
Confidence            567888999999999975 333 23445678888998887520    145678889999999998656677777778889


Q NP_000290.2     686 NNIINLCRS-----SA---SPKAAEAARLLLSDMWSSKELQGVLRQQG  725 (747)
Q Consensus       686 ~~Ll~LL~s-----~~---d~eVr~aAL~aLsnL~~~~~~~~~~~~~~  725 (747)
                      +.|+.++..     ..   .....+.++.+|..++...+.+..+...|
T Consensus       292 ~~LL~lL~~y~~~d~~~~~e~e~~en~~~aL~~L~~~~~~r~~f~~~~  339 (568)
T 4HM9_A          292 DVLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGE  339 (568)
T ss_dssp             HHHHHHHGGGTTSCCSSSHHHHHHHHHHHHHHHHTTSTHHHHHHHHTT
T ss_pred             HHHHHHHHhhhccCCCCHHHHHHHHHHHHHHHHHhCCHHHHHHHHHCC
Confidence            999998851     11   12345566889999888776655444443


No 171
>3L6X_A Catenin delta-1, E-cadherin; p120, catenin, cadherin, E-cadherin, armadillo; HET: SO4; 2.4A {Homo sapiens}
Probab=96.36  E-value=1.3e-05  Score=86.31  Aligned_cols=135  Identities=19%  Similarity=0.251  Sum_probs=86.7  Template_Neff=11.000

Q NP_000290.2     246 TIPKAVQYLSS------QDEKYQAIGAYYIQHTCFQDE-------------------------SAKQQVYQLGGICKLVD  294 (747)
Q Consensus       246 iL~~Ll~lL~s------sd~eVr~sAL~aLsnLs~~~~-------------------------~~~~~li~~~IL~~Ll~  294 (747)
                      +++.++.++..      .+..++..++.+|.+++....                         .....+...++++.+..
T Consensus       236 ~v~~L~~~l~~~~~~~~~~~~~~~~a~~~L~~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~  315 (584)
T 3L6X_A          236 LVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGTSPARGYELLFQPEVVRIYIS  315 (584)
T ss_dssp             HHHHHHHHHHHHHHTTCCSCHHHHHHHHHHHHHHTTHHHHSTTCCC--------------CCCCGGGGGGSHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhcCCCCChHHHHHHHHHHHHHHhhhhccChhHHHHHHhcCcCCCCCCCCChhhhhHhhChhHHHHHHH
Confidence            34555565553      356677888888888875421                         11223334567777777


Q NP_000290.2     295 LLRSP-NQNVQQAAAGALRNLVFRS----TTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA  369 (747)
Q Consensus       295 lL~s~-d~eVr~~AL~aLs~La~~~----~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve  369 (747)
                      ++... ++.++..++.+|.+++...    ......+...++++.+..++. ..+..++..++.+|.+++........+..
T Consensus       316 ll~~~~~~~~~~~a~~~L~~L~~~~~~~~~~~~~~~~~~~~l~~L~~ll~-~~~~~v~~~a~~~L~~L~~~~~~~~~l~~  394 (584)
T 3L6X_A          316 LLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLT-NEHERVVKAASGALRNLAVDARNKELIGK  394 (584)
T ss_dssp             HHHHCCCHHHHHHHHHHHHHHHSSCSHHHHHHHHHHTSHHHHHHHHHGGG-CSCHHHHHHHHHHHHHHHTTCSCHHHHHH
T ss_pred             HHHcCCCHHHHHHHHHHHHHHhCCCccCCHHHHHHHHHcChHHHHHHHhc-CCCHHHHHHHHHHHHHHhcChHHHHHHHc
Confidence            77765 7788889999999987642    222233334467778888886 56678888999999999876444333333


Q NP_000290.2     370 DALPVLADRVII  381 (747)
Q Consensus       370 giLe~Lv~LL~~  381 (747)
                      ++++.|+.+|..
T Consensus       395 ~~l~~L~~~L~~  406 (584)
T 3L6X_A          395 HAIPNLVKNLPG  406 (584)
T ss_dssp             HHHHHHHHTSSS
T ss_pred             chHHHHHHcCCC
Confidence            566666666643


No 172
>4U5L_A deltaIBB-importin-alpha1; TPX2, inhibitor, TRANSPORT PROTEIN; HET: 3D6; 2.53A {Mus musculus}
Probab=96.35  E-value=1.2e-05  Score=78.71  Aligned_cols=134  Identities=17%  Similarity=0.197  Sum_probs=87.3  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..++...+.....+...++++.+..++.+.++.++..++.++..++...+.....+
T Consensus       223 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  302 (426)
T 4U5L_A          223 VVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQV  302 (426)
T ss_dssp             CHHHHHHHHTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTGGGGHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCccHHHHHHHHHHHHhcCCHHHHHHHhccchHHHHHHHhcCCChHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            45566666666777888889999998886544333344445677778888877778888899999998886544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD--ELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~--~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++...  .....+.. ++++.|..++.
T Consensus       303 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  359 (426)
T 4U5L_A          303 VNHGLVPFLVGVLS-KADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLS  359 (426)
T ss_dssp             HHTTCHHHHHHHHH-SSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHTTCHHHHHHGGG
T ss_pred             HHCCHHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCCHHHHHHHHhCCcHHHHHHHhc
Confidence            33456777777776 456677888888888887631  11122222 45555555544


No 173
>2JDQ_A IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC; TRANSPORT, PB2 SUBUNIT, NUCLEAR PROTEIN; 2.2A {HOMO SAPIENS}
Probab=96.34  E-value=1.3e-05  Score=79.63  Aligned_cols=366  Identities=18%  Similarity=0.167  Sum_probs=218.3  Template_Neff=13.000

Q NP_000290.2     245 LTIPKAVQYLSS-QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~s-sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .+++.+...+.. .++.++..++.++..++.........+...++++.+...+.+.+..++..++.++..++........
T Consensus        64 ~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~  143 (450)
T 2JDQ_A           64 GVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRD  143 (450)
T ss_dssp             THHHHHHHHHTCTTCHHHHHHHHHHHHHHHSSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHH
T ss_pred             chHHHHHHHHccCCCHHHHHHHHHHHHHHhCCCcHHHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHH
Confidence            345556666655 5677888888888888765443333333456777888888777788899999999988765443333


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVIIPFSGWCDGNSNMSREVVDPE  401 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~  401 (747)
                      .+...++++.+...+....++.++..++.++..++...........  ++++.+..++..                .+++
T Consensus       144 ~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~  207 (450)
T 2JDQ_A          144 YVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFV----------------SDTD  207 (450)
T ss_dssp             HHHHTTCHHHHHHHTTSCCCHHHHHHHHHHHHHHHCCSSSCCCGGGTGGGHHHHHHHTTC----------------CCHH
T ss_pred             HHHHCCCHHHHHHHHhhccchhHHHHHHHHHHHHhcCCCCCchhhhhhhHHHHHHHHhcC----------------CCHH
Confidence            3334566777777776333457888888999888765432222221  455556655543                1334


Q NP_000290.2     402 VFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHN  481 (747)
Q Consensus       402 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  481 (747)
                      +...+..+|..-...      .+              ...+.. -..+++..|...+++      -+..-.+.++..|.+
T Consensus       208 ~~~~a~~~l~~l~~~------~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~  260 (450)
T 2JDQ_A          208 VLADACWALSYLSDG------PN--------------DKIQAV-IDAGVCRRLVELLMH------NDYKVVSPALRAVGN  260 (450)
T ss_dssp             HHHHHHHHHHHHTSS------SH--------------HHHHHH-HHTTTHHHHHHHTTC------SCHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhcC------CH--------------HHHHHH-HHCCHHHHHHHHHcC------CCHHHHHHHHHHHHH
Confidence            444444333221000      00              000000 012344444433321      011111222222222


Q NP_000290.2     482 LSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKK  561 (747)
Q Consensus       482 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d  561 (747)
                      +...-                                                  ......+.+.++++.++.++. +.+
T Consensus       261 l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~  289 (450)
T 2JDQ_A          261 IVTGD--------------------------------------------------DIQTQVILNCSALQSLLHLLS-SPK  289 (450)
T ss_dssp             HTTSC--------------------------------------------------HHHHHHHHTTTHHHHHHHHTT-CSS
T ss_pred             HhhCC--------------------------------------------------hHHHHHHhhcchHHHHHHHhc-CCC
Confidence            22100                                                  000112234567888888887 467


Q NP_000290.2     562 DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH--PLL-HRVMGNQVFP  638 (747)
Q Consensus       562 ~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~--~e~-~~ll~~giI~  638 (747)
                      +.++..++.+|.+++.....     ....+...++++.|..++.+.++.++..++.+|.+++..  +.. ..+...++++
T Consensus       290 ~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~  364 (450)
T 2JDQ_A          290 ESIKKEACWTISNITAGNRA-----QIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIK  364 (450)
T ss_dssp             HHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHTCHH
T ss_pred             HHHHHHHHHHHHHHhcCCHH-----HHHHHHhCCHHHHHHHHHhcCCHHHHHHHHHHHHHHhcCCCHHHHHHHHHCCcHH
Confidence            78888999999999875332     223334567888899998888888999999999999876  222 2334456788


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK-----------QYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~-----------~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .+..++.+      .++.++..++.+|.+++...+....           .+.+.+.++.+..++.+. ++.++..++.+
T Consensus       365 ~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~l~~~~-~~~v~~~a~~~  437 (450)
T 2JDQ_A          365 PLCDLLTV------MDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQSHE-NQEIYQKAFDL  437 (450)
T ss_dssp             HHHHGGGS------SCHHHHHHHHHHHHHHHHHHHHHHHHSCSCCCHHHHHHHHHHCHHHHHHHHCHH-HHHHHHHHHHH
T ss_pred             HHHHHhhC------CCHHHHHHHHHHHHHHHHHhHHHHhhCCCCCCHHHHHHHHhccHHHHHHHHhCC-CHHHHHHHHHH
Confidence            88888876      3678888999999999875332221           233445667776666665 77889999999


Q NP_000290.2     708 LSDMWSSKE  716 (747)
Q Consensus       708 LsnL~~~~~  716 (747)
                      +.++....+
T Consensus       438 l~~~~~~~~  446 (450)
T 2JDQ_A          438 IEHYFGTED  446 (450)
T ss_dssp             HHHHHCCC-
T ss_pred             HHHHhcCcc
Confidence            988876544


No 174
>3GQ2_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.18A {Bos taurus}
Probab=96.33  E-value=1.5e-05  Score=88.20  Aligned_cols=169  Identities=12%  Similarity=0.125  Sum_probs=105.6  Template_Neff=10.100

Q NP_000290.2     543 LYHSDAIRTYLNLMGKSKK----DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS-----DV--  611 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~d----~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~-----eV--  611 (747)
                      +++.|+++.|+.++.. ..    ..++..++.+|.+++..+..     ....+.+.++++.|..++...+.     ..  
T Consensus       204 l~~~g~~~~L~~ll~~-~~~~~~~~v~~~al~~L~~L~~~~~~-----~~~~~~e~~~i~~L~~lL~~~~~~~~~~~~~~  277 (651)
T 3GQ2_A          204 VAFENAFERLLDIITE-EGNSDGGIVVEDCLILLQNLLKNNNS-----NQNFFKEGSYIQRMKPWFEVGDENSGWSAQKV  277 (651)
T ss_dssp             HHHTTHHHHHHHHHHH-TTGGGSHHHHHHHHHHHHHHHTTCHH-----HHHHHHHTTCGGGTGGGGCCCSSCCCCCHHHH
T ss_pred             HHhCChHHHHHHHHHH-hCCCCccHHHHHHHHHHHHHHhCCHH-----HHHHHHhcChHHHHHHHHhcCCccCCCchHHH
Confidence            4577889999998873 32    25777899999999875432     34455567889999988874331     11  


Q NP_000290.2     612 --VRSGASLLSNMSRH-------PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFS  681 (747)
Q Consensus       612 --r~~AL~aLsnLa~~-------~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve  681 (747)
                        ...++.++..++..       ... ..+...++++.|+.++....    .+..++..++.+|++++..++.....+.+
T Consensus       278 ~~~~~~~~il~~l~~~~~~~~~~~~~~~~l~~~g~l~~L~~ll~~~~----~~~~v~~~a~~~La~l~~~~~~~q~~~~~  353 (651)
T 3GQ2_A          278 TNLHLMLQLVRVLVSPNNPPGATSSCQKAMFQCGLLQQLCTILMATG----VPADILTETINTVSEVIRGCQVNQDYFAS  353 (651)
T ss_dssp             HHHHHHHHHHHHHHCTTSCHHHHHHHHHHHHHTTHHHHHHHHHHCSS----CCHHHHHHHHHHHHHHHTTCHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHhCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHhcC----CCHHHHHHHHHHHHHHHhcCHHHHHHHHh
Confidence              22334444444421       112 23356678888888886520    14578889999999998865555444444


Q NP_000290.2     682 S--------SMLNNIINLCRSS-ASPKAAEAARLLLSDMWSS-KELQGVL  721 (747)
Q Consensus       682 ~--------giL~~Ll~LL~s~-~d~eVr~aAL~aLsnL~~~-~~~~~~~  721 (747)
                      .        +.+..|+.++... .+..++..++.+|.+++.. .+.+..+
T Consensus       354 ~~~~~~~~~~~l~~Ll~~l~~~~~~~~~r~~al~~L~~~~~~~~~~~~~l  403 (651)
T 3GQ2_A          354 VNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNQKGQGEI  403 (651)
T ss_dssp             CBCCSSSCCBHHHHHHHHHTCTTSCHHHHHHHHHHHHHHHTTCHHHHHHH
T ss_pred             CCCCCCCCchHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHhcCHHHHHHH
Confidence            2        2355666665432 1567888999999666653 3334333


No 175
>3GRL_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.0A {Bos taurus}
Probab=96.33  E-value=1.5e-05  Score=88.20  Aligned_cols=169  Identities=12%  Similarity=0.125  Sum_probs=105.6  Template_Neff=10.100

Q NP_000290.2     543 LYHSDAIRTYLNLMGKSKK----DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS-----DV--  611 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~d----~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~-----eV--  611 (747)
                      +++.|+++.|+.++.. ..    ..++..++.+|.+++..+..     ....+.+.++++.|..++...+.     ..  
T Consensus       204 l~~~g~~~~L~~ll~~-~~~~~~~~v~~~al~~L~~L~~~~~~-----~~~~~~e~~~i~~L~~lL~~~~~~~~~~~~~~  277 (651)
T 3GRL_A          204 VAFENAFERLLDIITE-EGNSDGGIVVEDCLILLQNLLKNNNS-----NQNFFKEGSYIQRMKPWFEVGDENSGWSAQKV  277 (651)
T ss_dssp             HHHTTHHHHHHHHHHH-HTGGGSHHHHHHHHHHHHHHHTTCHH-----HHHHHHHTTCGGGGGGGGCCCSCSSCCCHHHH
T ss_pred             HHhCChHHHHHHHHHH-hCCCCccHHHHHHHHHHHHHHhCCHH-----HHHHHHhcChHHHHHHHHhcCCccCCCchHHH
Confidence            4577889999998873 32    25777899999999875432     34455567889999988874331     11  


Q NP_000290.2     612 --VRSGASLLSNMSRH-------PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFS  681 (747)
Q Consensus       612 --r~~AL~aLsnLa~~-------~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve  681 (747)
                        ...++.++..++..       ... ..+...++++.|+.++....    .+..++..++.+|++++..++.....+.+
T Consensus       278 ~~~~~~~~il~~l~~~~~~~~~~~~~~~~l~~~g~l~~L~~ll~~~~----~~~~v~~~a~~~La~l~~~~~~~q~~~~~  353 (651)
T 3GRL_A          278 TNLHLMLQLVRVLVSPNNPPGATSSCQKAMFQCGLLQQLCTILMATG----VPADILTETINTVSEVIRGCQVNQDYFAS  353 (651)
T ss_dssp             HHHHHHHHHHHHHTCTTSCHHHHHHHHHHHHHTTHHHHHHHHHTCSS----CCHHHHHHHHHHHHHHHTTCHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHhCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHhcC----CCHHHHHHHHHHHHHHHhcCHHHHHHHHh
Confidence              22334444444421       112 23356678888888886520    14578889999999998865555444444


Q NP_000290.2     682 S--------SMLNNIINLCRSS-ASPKAAEAARLLLSDMWSS-KELQGVL  721 (747)
Q Consensus       682 ~--------giL~~Ll~LL~s~-~d~eVr~aAL~aLsnL~~~-~~~~~~~  721 (747)
                      .        +.+..|+.++... .+..++..++.+|.+++.. .+.+..+
T Consensus       354 ~~~~~~~~~~~l~~Ll~~l~~~~~~~~~r~~al~~L~~~~~~~~~~~~~l  403 (651)
T 3GRL_A          354 VNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNQKGQGEI  403 (651)
T ss_dssp             CEESSSSCEEHHHHHHHHHTCTTSCHHHHHHHHHHHHHHHTTCHHHHHHH
T ss_pred             CCCCCCCCchHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHhcCHHHHHHH
Confidence            2        2355666665432 1567888999999666653 3334333


No 176
>3TT9_A Plakophilin-2; CELL ADHESION; HET: GOL; 1.55A {Homo sapiens}
Probab=96.31  E-value=1.5e-05  Score=72.85  Aligned_cols=113  Identities=18%  Similarity=0.215  Sum_probs=69.5  Template_Neff=12.300

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP---------------NQNVQQAAAG  309 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~---------------d~eVr~~AL~  309 (747)
                      +++.++.++. ..+..++..++.++.+++... .....+...+++..+..++...               +..++..++.
T Consensus        95 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~-~~~~~~~~~~~~~~l~~ll~~~~~~~~~~~~~~~~~~~~~~~~~a~~  173 (233)
T 3TT9_A           95 GVPRLLQVLKQTRDLETKKQITGLLWNLSSND-KLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTG  173 (233)
T ss_dssp             HHHHHHHHHHHCCCHHHHHHHHHHHHHHHTSG-GGHHHHHHHHHHHHCCCCCHHHHCCCGGGCCCCCTTCCHHHHHHHHH
T ss_pred             cHHHHHHHHhhCCCHHHHHHHHHHHHHHccCH-HHHHHhhhhcHHHHHHHHHhhccCCCCCCCCcccCCCcHHHHHHHHH
Confidence            4555666665 456778888999999987633 2233333344555555554322               4567778888


Q NP_000290.2     310 ALRNLVFRSTTNKLETRRQNG-IREAVSLLRRTG------NAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       310 aLs~La~~~~~~~~~ll~~~I-L~~Ll~lL~ss~------d~eVr~~AL~aLsnLas~  360 (747)
                      ++.+++...+.....+...+. ++.+..++. ..      ++.++..++.+|.+++..
T Consensus       174 ~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~~~~L~~l~~~  230 (233)
T 3TT9_A          174 CLRNMSSAGADGRKAMRRCDGLIDSLVHYVR-GTIADYQPDDKATENCVCILHNLSYQ  230 (233)
T ss_dssp             HHHHHTTSCHHHHHHHHTSTTHHHHHHHHHH-HHHHTTCTTCHHHHHHHHHHHHHCCC
T ss_pred             HHHHHHhcCHHHHHHHHHcccHHHHHHHHHH-cccccCCCChHHHHHHHHHHHHhhhc
Confidence            888887643333333433344 777777775 33      466777788888777653


No 177
>5D5K_C Importin subunit alpha-1, Poly [ADP-ribose]; PARP-2 NLS, PARP-2, poly(ADP-ribose)polymerase-2, Importin; 1.9A {Mus musculus}
Probab=96.29  E-value=1.5e-05  Score=79.23  Aligned_cols=113  Identities=17%  Similarity=0.142  Sum_probs=78.1  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS-TTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~-~~~~~~  324 (747)
                      +++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.++.++..++.++..++... ......
T Consensus       273 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~  352 (466)
T 5D5K_C          273 ALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVY  352 (466)
T ss_dssp             GGGGHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHHHHSSCHHHHHHHHHHHHHHHHHSCHHHHHH
T ss_pred             hhHhHHHHhhCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHH
Confidence            4555666666667788888999998887654433333444467777888887777788889999998887642 222222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      +...++++.+...+. ..++.++..++.++..++.
T Consensus       353 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~  386 (466)
T 5D5K_C          353 LVHCGIIEPLMNLLS-AKDTKIIQVILDAISNIFQ  386 (466)
T ss_dssp             HHHTTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHH
T ss_pred             HHhCCcHHHHHHHhh-cCCHHHHHHHHHHHHHHHH
Confidence            333346777777776 5567788889999988876


No 178
>4UAF_B Importin alpha 1 import receptor; importin karyopherin complex NLS, PROTEIN; HET: PO4; 1.698A {Mus musculus}
Probab=96.28  E-value=1.6e-05  Score=79.14  Aligned_cols=113  Identities=17%  Similarity=0.142  Sum_probs=78.0  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS-TTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~-~~~~~~  324 (747)
                      +++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.++.++..++.++..++... ......
T Consensus       273 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~  352 (466)
T 4UAF_B          273 ALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVY  352 (466)
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHH
Confidence            4555666666667788888999999887654433333444467777888887777788889999998887642 222222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      +...++++.+...+. ..++.++..++.++..++.
T Consensus       353 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~  386 (466)
T 4UAF_B          353 LVHCGIIEPLMNLLS-AKDTKIIQVILDAISNIFQ  386 (466)
T ss_pred             HHhCCcHHHHHHHhh-cCCHHHHHHHHHHHHHHHH
Confidence            333346777777776 5567788889999988876


No 179
>2JDQ_A IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC; TRANSPORT, PB2 SUBUNIT, NUCLEAR PROTEIN; 2.2A {HOMO SAPIENS}
Probab=96.23  E-value=1.8e-05  Score=78.41  Aligned_cols=134  Identities=18%  Similarity=0.203  Sum_probs=87.8  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++..++.........+...++++.+...+.+.++.++..++.++..++..........
T Consensus       235 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  314 (450)
T 2JDQ_A          235 VCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTV  314 (450)
T ss_dssp             THHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHTTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHHcCCCHHHHHHHHHHHHHHhhCChHHHHHHhhcchHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            45566666666677888889999998887544333333334677778888877777888899999998876544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST--DELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~--~~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++..  ......+.. ++++.|..++.
T Consensus       315 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  371 (450)
T 2JDQ_A          315 IDANIFPALISILQ-TAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLT  371 (450)
T ss_dssp             HHTTHHHHHHHHHH-HSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHTCHHHHHHGGG
T ss_pred             HhCCHHHHHHHHHh-cCCHHHHHHHHHHHHHHhcCCCHHHHHHHHHCCcHHHHHHHhh
Confidence            34457777777776 55677888888888888764  222222222 45555555554


No 180
>3IFQ_A plakoglobin, E-cadherin; armadillo repeat, Cardiomyopathy, Cell adhesion; HET: SO4; 2.8A {Homo sapiens}
Probab=96.23  E-value=1.8e-05  Score=80.55  Aligned_cols=367  Identities=18%  Similarity=0.234  Sum_probs=218.1  Template_Neff=13.100

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP-NQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~-d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .+++.+...+.+.++.++..++.++..+....+.....+...++++.+...+... +..++..++.++..+..... ...
T Consensus       145 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~-~~~  223 (553)
T 3IFQ_A          145 DGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPS-NKP  223 (553)
T ss_dssp             TGGGGTGGGGGSSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTSTT-HHH
T ss_pred             CHHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHHhcCCcHHHHHHHHHHHHHHhCCcc-hHH
Confidence            4556666667667778888899999988764443333333445677777777654 56778888888888876322 222


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      .+...++++.+...+. ..++.++..++.++..++....... ...++++.+..++..                .++++.
T Consensus       224 ~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~-~~~~~~~~l~~~l~~----------------~~~~~~  285 (553)
T 3IFQ_A          224 AIVEAGGMQALGKHLT-SNSPRLVQNCLWTLRNLSDVATKQE-GLESVLKILVNQLSV----------------DDVNVL  285 (553)
T ss_dssp             HHHHTTHHHHHHGGGG-SSCHHHHHHHHHHHHHHHTTCTTCS-CCHHHHHHHHTTTTC----------------CCHHHH
T ss_pred             HHHHCchHHHHHHHHh-cCCHHHHHHHHHHHHHhCChhHHHH-HHHHHHHHHHHHcCC----------------CCHHHH
Confidence            3333456777777776 5567788888888888876432211 112455555555532                133333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-..      ..+              ...+.+. -.+.++.++..+..    ..-+..-.+.+..+|.++.
T Consensus       286 ~~a~~~l~~l~~------~~~--------------~~~~~~~-~~~~~~~l~~~l~~----~~~~~~~~~~a~~~l~~l~  340 (553)
T 3IFQ_A          286 TCATGTLSNLTC------NNS--------------KNKTLVT-QNSGVEALIHAILR----AGDKDDITEPAVCALRHLT  340 (553)
T ss_dssp             HHHHHHHHHHTT------TCH--------------HHHHHHT-TTTHHHHHHHHHHH----HTTCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHHc------CCH--------------HHHHHHH-HccHHHHHHHHHHH----cCCChHhHHHHHHHHHHHh
Confidence            333333321100      000              0000000 01233333332211    0011222333344444443


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ...+..                                               ......+...++++.++.++....++.
T Consensus       341 ~~~~~~-----------------------------------------------~~~~~~~~~~~~~~~l~~~l~~~~~~~  373 (553)
T 3IFQ_A          341 SRHPEA-----------------------------------------------EMAQNSVRLNYGIPAIVKLLNQPNQWP  373 (553)
T ss_dssp             SSSTTH-----------------------------------------------HHHHHHHHTTTHHHHHHHGGGCTTCHH
T ss_pred             cCCChH-----------------------------------------------HHHHHHHHHcchHHHHHHHHcCCCChH
Confidence            211100                                               000112234566788888887322367


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS---------------------DVVRSGASLLSNM  622 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~---------------------eVr~~AL~aLsnL  622 (747)
                      ++..++.+|.+++....      ....+...++++.|..++.+.+.                     .++..++.+|.++
T Consensus       374 ~~~~a~~~l~~l~~~~~------~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l  447 (553)
T 3IFQ_A          374 LVKATIGLIRNLALCPA------NHAPLQEAAVIPRLVQLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCTGALHIL  447 (553)
T ss_dssp             HHHHHHHHHHHHTTSGG------GHHHHHHTTHHHHHHHHHHHHHHHHHHHHHTTCCCTTCSSCCHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhcCcc------cHHHHHHccHHHHHHHHHHHcCcchhHHHhhcccCccccCCCHHHHHHHHHHHHHHH
Confidence            78889999999887532      12333456788888888876554                     7888899999998


Q NP_000290.2     623 SRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA  701 (747)
Q Consensus       623 a~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr  701 (747)
                      +..... ......++++.+..++.+      .++.++..++.+|.+++.. +.....+.+.++++.|..++.+. ++.++
T Consensus       448 ~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~-~~~~~~~~~~~~~~~l~~~l~~~-~~~v~  519 (553)
T 3IFQ_A          448 ARDPMNRMEIFRLNTIPLFVQLLYS------SVENIQRVAAGVLCELAQD-KEAADAIDAEGASAPLMELLHSR-NEGTA  519 (553)
T ss_dssp             TTSHHHHHHHHHTTCHHHHHHHTTC------SCHHHHHHHHHHHHHHTTS-HHHHHHHHHTTTHHHHHHHTTCS-SHHHH
T ss_pred             hcChhhHHHHHHcCChHHHHHHHhC------CCHHHHHHHHHHHHHHHcC-HHHHHHHHHCCcHHHHHHHHhCC-CHHHH
Confidence            875333 233445677888888775      3678899999999999875 44555555667888898888877 78899


Q NP_000290.2     702 EAARLLLSDMWSSKE  716 (747)
Q Consensus       702 ~aAL~aLsnL~~~~~  716 (747)
                      ..++.+|.+++...+
T Consensus       520 ~~a~~~l~~l~~~~~  534 (553)
T 3IFQ_A          520 TYAAAVLFRISEDKN  534 (553)
T ss_dssp             HHHHHHHHHTTSTTC
T ss_pred             HHHHHHHHHHHcccC
Confidence            999999999996543


No 181
>4BQK_A IMPORTIN SUBUNIT ALPHA-1A, T-DNA BORDER; TRANSPORT PROTEIN, HYDROLASE, NUCLEAR LOCALIZATION; HET: PEG; 1.997A {ORYZA SATIVA}
Probab=96.23  E-value=1.9e-05  Score=78.53  Aligned_cols=116  Identities=19%  Similarity=0.202  Sum_probs=77.5  Template_Neff=13.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.+..++..++.++..+....+.....+...++++.+...+.+.+..++..++.++..++.........
T Consensus       172 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  251 (456)
T 4BQK_A          172 PALPALARLIHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDAQTQC  251 (456)
T ss_dssp             THHHHHHHHTTCCCHHHHHHHHHHHHHHTSSSHHHHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCChHHHHHHHHCChHHHHHHHHhCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            34556666666677788888999998887654433333334466777777777777788888999998887654333233


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      +...++++.+...+....++.++..++.++..++..
T Consensus       252 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~  287 (456)
T 4BQK_A          252 IIDHQALPCLLSLLTQNLKKSIKKEACWTISNITAG  287 (456)
T ss_dssp             HHTTTHHHHHHHHHHSCCCHHHHHHHHHHHHHHHTS
T ss_pred             HHHCChHHHHHHHHHcCCCHHHHHHHHHHHHHHhcC
Confidence            333456677777775222566777888888887754


No 182
>4U5L_A deltaIBB-importin-alpha1; TPX2, inhibitor, TRANSPORT PROTEIN; HET: 3D6; 2.53A {Mus musculus}
Probab=96.17  E-value=2.2e-05  Score=76.74  Aligned_cols=115  Identities=21%  Similarity=0.205  Sum_probs=78.3  Template_Neff=13.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.++.++..++.++..++...+.....
T Consensus       180 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  259 (426)
T 4U5L_A          180 QILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQK  259 (426)
T ss_dssp             HHHHHHHHHTTSSCHHHHHHHHHHHHHHTSSCHHHHHHHHTTTCHHHHHHHHTCSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             HHHHHHHHHHhCCCHHHHHHHHHHHHHHhhCCcHHHHHHhhcChHHHHHHHhcCCCccHHHHHHHHHHHHhcCCHHHHHH
Confidence            45556666666677788888999998887654433333344457777888887777788889999998888654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      +...++++.+...+. +.++.++..++.++..++..
T Consensus       260 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  294 (426)
T 4U5L_A          260 VIDAGALAVFPSLLT-NPKTNIQKEATWTMSNITAG  294 (426)
T ss_dssp             HHHTTGGGGHHHHTT-CSSHHHHHHHHHHHHHHTTS
T ss_pred             HhccchHHHHHHHhc-CCChHHHHHHHHHHHHHhcC
Confidence            334456677777775 45667777777777777653


No 183
>4BPL_A IMPORTIN SUBUNIT ALPHA-1A, NUCLEOPLASMIN NLS; TRANSPORT PROTEIN, NUCLEAR IMPORT, NUCLEAR; 2.3A {ORYZA SATIVA}
Probab=96.16  E-value=2.3e-05  Score=77.77  Aligned_cols=135  Identities=18%  Similarity=0.197  Sum_probs=84.9  Template_Neff=13.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.+..++..++.++..+....+.....+...++++.+...+.+.+..++..++.++..++.........
T Consensus       170 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  249 (454)
T 4BPL_A          170 PALPALARLIHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDAQTQC  249 (454)
T ss_dssp             THHHHHHHHTTCCCHHHHHHHHHHHHHHTSSCHHHHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             HHHHHHHHHHhCCCHHHHHHHHHHHHHHhcCChHHHHHHHHCCcHHHHHHHhhCCChHHHHHHHHHHHHHhcCCHHHHHH
Confidence            34556666666677788888999998887654433333334456777777777777788888999998887654333233


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRV  379 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL  379 (747)
                      +...++++.+...+....++.++..++.++..++..... ...+.. ++++.|..++
T Consensus       250 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l  306 (454)
T 4BPL_A          250 IIDHQALPCLLSLLTQNLKKSIKKEACWTISNITAGNKDQIQAVINAGIIGPLVNLL  306 (454)
T ss_dssp             HHTTTHHHHHHHHHHSSCCHHHHHHHHHHHHHHHTSCHHHHHHHHHHTCHHHHHHHH
T ss_pred             HHHCChHHHHHHHHHhcCCHHHHHHHHHHHHHHhcCCHHHHHHHHhCCcHHHHHHHh
Confidence            333456677777775222567778888888887754321 112222 4555555544


No 184
>4MZ6_E Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin; ARM repeat, protein transport, Importin; 1.88A {Mus musculus}
Probab=96.12  E-value=2.6e-05  Score=79.03  Aligned_cols=113  Identities=17%  Similarity=0.142  Sum_probs=77.9  Template_Neff=12.800

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS-TTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~-~~~~~~  324 (747)
                      +++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.++.++..++.++..++... ......
T Consensus       317 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~  396 (509)
T 4MZ6_E          317 ALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVY  396 (509)
T ss_dssp             GGGGHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHHHSSCHHHHHHHHHHHHHHHHHSCHHHHHH
T ss_pred             hHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHH
Confidence            4455566666667788888999998887654433333444467777888887777788889999998887642 222223


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      +...++++.+...+. ..++.++..++.++..++.
T Consensus       397 ~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~  430 (509)
T 4MZ6_E          397 LVHCGIIEPLMNLLS-AKDTKIIQVILDAISNIFQ  430 (509)
T ss_dssp             HHHTTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHH
T ss_pred             HHhCCCHHHHHHHHh-CCCHHHHHHHHHHHHHHHH
Confidence            333346777777776 5567788889999988876


No 185
>5UMZ_B Importin subunit alpha-1, TNRC6A; mRNA decay, miRNA ARM repeat; HET: GOL; 1.9A {Mus musculus}
Probab=96.12  E-value=2.6e-05  Score=79.03  Aligned_cols=113  Identities=17%  Similarity=0.142  Sum_probs=77.9  Template_Neff=12.800

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS-TTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~-~~~~~~  324 (747)
                      +++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.++.++..++.++..++... ......
T Consensus       317 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~  396 (509)
T 5UMZ_B          317 ALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVY  396 (509)
T ss_dssp             GGGGHHHHTTCSSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHHHSSCHHHHHHHHHHHHHHHHHSCHHHHHH
T ss_pred             hHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHH
Confidence            4455566666667788888999998887654433333444467777888887777788889999998887642 222223


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      +...++++.+...+. ..++.++..++.++..++.
T Consensus       397 ~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~  430 (509)
T 5UMZ_B          397 LVHCGIIEPLMNLLS-AKDTKIIQVILDAISNIFQ  430 (509)
T ss_dssp             HHHTTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHH
T ss_pred             HHhCCCHHHHHHHHh-CCCHHHHHHHHHHHHHHHH
Confidence            333346777777776 5567788889999988876


No 186
>4E4V_A Importin subunit alpha-2; armadillo repeat, karyopherin, importin, nuclear; HET: GOL, DTT; 2.5283A {Homo sapiens}
Probab=96.12  E-value=2.7e-05  Score=78.66  Aligned_cols=113  Identities=17%  Similarity=0.130  Sum_probs=78.1  Template_Neff=12.700

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRST-TNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~-~~~~~  324 (747)
                      +++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.++.++..++.++..++.... .....
T Consensus       292 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  371 (485)
T 4E4V_A          292 ALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVY  371 (485)
T ss_dssp             GGGGHHHHHTCSSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHSCHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHcCCCHHHHHHHHHCCHHHHHHHHHhcCCHHHHHHHHHHHHHHHhcCCHHHHHH
Confidence            45556666666677888889999998876544333334444677778888877777888889999988876422 22222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      +...++++.+...+. ..++.++..++.++..++.
T Consensus       372 ~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~  405 (485)
T 4E4V_A          372 LVHCGIIEPLMNLLT-AKDTKIILVILDAISNIFQ  405 (485)
T ss_dssp             HHHTTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHH
T ss_pred             HHhCCcHHHHHHHhh-cCCHHHHHHHHHHHHHHHH
Confidence            333346777777776 5567788889999988886


No 187
>3GQ2_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.18A {Bos taurus}
Probab=96.07  E-value=3.4e-05  Score=85.21  Aligned_cols=176  Identities=12%  Similarity=0.192  Sum_probs=126.8  Template_Neff=10.100

Q NP_000290.2     543 LYHSDAIRTYLNLMGKS-KKDATLEACAGALQNLTASKGLMSSG--------------MSQLIGL-KEKGLPQIARLLQS  606 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s~~~s~~--------------~~~~lli-e~giI~~Ll~LL~s  606 (747)
                      ++..++++.|+.+|... .+..++..++.+|.+++...+.  ..              .....+. +.+.++.|+.++.+
T Consensus        56 ~v~~~~l~~Li~~L~~~~~d~~~~~~al~~L~~l~~~~~~--~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~Ll~ll~~  133 (651)
T 3GQ2_A           56 EVGIQAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNDEE--EEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEE  133 (651)
T ss_dssp             HHHHHHHHHHHHHHTTCTTCHHHHHHHHHHHHHHHCCSSS--CC----------CHHHHHHHHHHTSHHHHHTHHHHTTC
T ss_pred             HHHccHHHHHHHHHhcCCCCHHHHHHHHHHHHHHhCCCCh--HhhhhcccccchHHHHHHHHHHHhcCchHHHHHHHccC
Confidence            46778999999999731 3567788899999998864321  00              0012223 57888999999888


Q NP_000290.2     607 GNSDVVRSGASLLSNMSRHP--LLH-RVM-GNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSS  682 (747)
Q Consensus       607 ~d~eVr~~AL~aLsnLa~~~--e~~-~ll-~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~  682 (747)
                      .++.++..++++|.+++...  ... .++ ..++++.|+.+|.+      .+..++..++.+|.+++..+++....+...
T Consensus       134 ~~~~~~~~al~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~~------~~~~i~~~a~~~L~~l~~~~~~~~~~l~~~  207 (651)
T 3GQ2_A          134 FDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLAD------SREVIRNDGVLLLQALTRSNGAIQKIVAFE  207 (651)
T ss_dssp             CCHHHHHHHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHGGGGGC------SSHHHHHHHHHHHHHHHTTCHHHHHHHHHT
T ss_pred             CCHHHHHHHHHHHHHHHHhccHHHHHHHHhCccHHHHHHHHhcC------CCHHHHHHHHHHHHHHhCCCHHHHHHHHhC
Confidence            88889999999999998773  222 233 45678889998876      367888999999999998555666666677


Q NP_000290.2     683 SMLNNIINLCRSSAS---PKAAEAARLLLSDMWSSK-ELQGVLRQQGF  726 (747)
Q Consensus       683 giL~~Ll~LL~s~~d---~eVr~aAL~aLsnL~~~~-~~~~~~~~~~~  726 (747)
                      ++++.|+.++.....   ..++..++.+|.+|+... ..+..++..|+
T Consensus       208 g~~~~L~~ll~~~~~~~~~~v~~~al~~L~~L~~~~~~~~~~~~e~~~  255 (651)
T 3GQ2_A          208 NAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSY  255 (651)
T ss_dssp             THHHHHHHHHHHTTGGGSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTC
T ss_pred             ChHHHHHHHHHHhCCCCccHHHHHHHHHHHHHHhCCHHHHHHHHhcCh
Confidence            889999998875411   257888999999988644 44555555554


No 188
>3GRL_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.0A {Bos taurus}
Probab=96.07  E-value=3.4e-05  Score=85.21  Aligned_cols=176  Identities=12%  Similarity=0.192  Sum_probs=126.4  Template_Neff=10.100

Q NP_000290.2     543 LYHSDAIRTYLNLMGKS-KKDATLEACAGALQNLTASKGLMSSG--------------MSQLIGL-KEKGLPQIARLLQS  606 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s~~~s~~--------------~~~~lli-e~giI~~Ll~LL~s  606 (747)
                      ++..++++.|+.+|... .+..++..++.+|.+++...+.  ..              .....+. +.+.++.|+.++.+
T Consensus        56 ~v~~~~l~~Li~~L~~~~~d~~~~~~al~~L~~l~~~~~~--~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~Ll~ll~~  133 (651)
T 3GRL_A           56 EVGIQAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNDEE--EEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEE  133 (651)
T ss_dssp             HCCCCCHHHHHHHHHSCTTCHHHHHHHHHHHHHHHCCC----------------CHHHHHHHHHHHSTHHHHHHHHHTTC
T ss_pred             HHHccHHHHHHHHHhcCCCCHHHHHHHHHHHHHHhCCCCh--HhhhhcccccchHHHHHHHHHHHhcCchHHHHHHHccC
Confidence            46778999999999731 3567788899999998864321  00              0012223 57888999999888


Q NP_000290.2     607 GNSDVVRSGASLLSNMSRHP--LLH-RVM-GNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSS  682 (747)
Q Consensus       607 ~d~eVr~~AL~aLsnLa~~~--e~~-~ll-~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~  682 (747)
                      .++.++..++++|.+++...  ... .++ ..++++.|+.+|.+      .+..++..++.+|.+++..+++....+...
T Consensus       134 ~~~~~~~~al~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~~------~~~~i~~~a~~~L~~l~~~~~~~~~~l~~~  207 (651)
T 3GRL_A          134 FDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLAD------SREVIRNDGVLLLQALTRSNGAIQKIVAFE  207 (651)
T ss_dssp             CCHHHHHHHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHHGGGGC------SSHHHHHHHHHHHHHHHTTCHHHHHHHHHT
T ss_pred             CCHHHHHHHHHHHHHHHHhccHHHHHHHHhCccHHHHHHHHhcC------CCHHHHHHHHHHHHHHhCCCHHHHHHHHhC
Confidence            88889999999999998773  222 233 45678889998876      367888999999999998555666666677


Q NP_000290.2     683 SMLNNIINLCRSSAS---PKAAEAARLLLSDMWSSK-ELQGVLRQQGF  726 (747)
Q Consensus       683 giL~~Ll~LL~s~~d---~eVr~aAL~aLsnL~~~~-~~~~~~~~~~~  726 (747)
                      ++++.|+.++.....   ..++..++.+|.+|+... ..+..++..|+
T Consensus       208 g~~~~L~~ll~~~~~~~~~~v~~~al~~L~~L~~~~~~~~~~~~e~~~  255 (651)
T 3GRL_A          208 NAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSY  255 (651)
T ss_dssp             THHHHHHHHHHHHTGGGSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTC
T ss_pred             ChHHHHHHHHHHhCCCCccHHHHHHHHHHHHHHhCCHHHHHHHHhcCh
Confidence            889999998875411   257888999999988644 44555555554


No 189
>4V3Q_A YIII_M4_AII; DE NOVO PROTEIN, PROTEIN ENGINEERING; HET: GOL, CA; 1.8A {SYNTHETIC CONSTRUCT}
Probab=96.03  E-value=3.4e-05  Score=69.70  Aligned_cols=112  Identities=26%  Similarity=0.317  Sum_probs=74.8  Template_Neff=12.900

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++.+++...+.....+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus       135 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  214 (247)
T 4V3Q_A          135 ALPALVQLLSSPNEQILQEALWTLGNIASGGDEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAV  214 (247)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666677788888899988876543333333344567777777777777888889999988886543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ...++++.+..++. ..++.++..++.++..+.
T Consensus       215 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~  246 (247)
T 4V3Q_A          215 KEAGALEKLEQLQS-HENEKIQKEAQEALEKLQ  246 (247)
T ss_dssp             HHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHT
T ss_pred             HHcCHHHHHHHHHh-CChHHHHHHHHHHHHHHc
Confidence            33456677777775 456677777777776653


No 190
>4TNM_A Importin-alpha3 / MOS6; armadillo repeat; 2.9A {Arabidopsis thaliana}
Probab=96.03  E-value=3.5e-05  Score=79.51  Aligned_cols=136  Identities=16%  Similarity=0.178  Sum_probs=85.8  Template_Neff=12.300

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..++.........+...++++.+...+.+.++.++..++.++..++.........
T Consensus       245 ~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  324 (531)
T 4TNM_A          245 PALPVLERLVQSMDEEVLTDACWALSYLSDNSNDKIQAVIEAGVVPRLIQLLGHSSPSVLIPALRTIGNIVTGDDLQTQM  324 (531)
T ss_pred             chHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCChHHHHHHHHhCCCHHHHHHHHHHHHHHHCCCHHHHHH
Confidence            34555666666667778888889988887654433333344467777778787777788888999998887654333223


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ....++++.+..++....++.++..++.++..++... .....+.. ++++.|..++.
T Consensus       325 ~~~~~~~~~l~~~l~~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~  382 (531)
T 4TNM_A          325 VLDQQALPCLLNLLKNNYKKSIKKEACWTISNITAGNADQIQAVIDAGIIQSLVWVLQ  382 (531)
T ss_pred             HHHCCcHHHHHHHhcCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCcHHHHHHHhc
Confidence            3333566777777752235677888888888887643 22222222 45555555553


No 191
>4GMO_A Putative uncharacterized protein; ARM, HEAT, solenoid, nuclear transport; 2.1A {Chaetomium thermophilum var. thermophilum DSM 1495}
Probab=95.93  E-value=5.4e-05  Score=85.22  Aligned_cols=94  Identities=14%  Similarity=0.083  Sum_probs=69.0  Template_Neff=8.600

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLV-DLLRSPNQNVQQAAAGALRNLVFRS-TTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll-~lL~s~d~eVr~~AL~aLs~La~~~-~~~~  322 (747)
                      ..+..|+..|.+.++.++..++.+|.+++.. +.....+...++++.|+ .++.+.+..++..++.+|.+++... ....
T Consensus        34 ~~i~~Li~~L~S~~~~~r~~A~~aL~~L~~d-~~~r~~l~~~g~i~~Li~~LL~d~~~~v~~~A~~aLrNLs~~~~~~~~  112 (684)
T 4GMO_A           34 DKILPVLKDLKSPDAKSRTTAAGAIANIVQD-AKCRKLLLREQVVHIVLTETLTDNNIDSRAAGWEILKVLAQEEEADFC  112 (684)
T ss_dssp             CCCHHHHHHHSSSCCSHHHHHHHHHHHHTTS-HHHHHHHHHTTHHHHCCCCCTTCSCHHHHHHHHHHHHHHHHHSCHHHH
T ss_pred             CChHHHHHHcCCCCHHHHHHHHHHHHHHhcC-HHHHHHHHHCChHHHHHHHHccCCCHHHHHHHHHHHHHHhccCChHHH
Confidence            4566778888888888999999999998763 44555566678888888 8888878889999999999998652 2333


Q NP_000290.2     323 LETRRQNGIREAVSLLR  339 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~  339 (747)
                      ..+...+++..|..++.
T Consensus       113 ~~l~~~g~l~~L~~lL~  129 (684)
T 4GMO_A          113 VHLYRLDVLTAIEHAAK  129 (684)
T ss_dssp             HHHHHTTHHHHHHHHHH
T ss_pred             HHHHHCChHHHHHHHHH
Confidence            34444566676666664


No 192
>4PLS_B Arm00010; PEPTIDE BINDING PROTEIN, designed armadillo; HET: CA; 2.35A {synthetic construct}
Probab=95.89  E-value=4.9e-05  Score=69.42  Aligned_cols=134  Identities=25%  Similarity=0.295  Sum_probs=87.2  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.+..++..++.++..++..........
T Consensus        86 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  165 (281)
T 4PLS_B           86 ALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAV  165 (281)
T ss_dssp             CHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             cHHHHHHHcCCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCHHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666677788888888888876543333333344677777777777777888899999988876543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus       166 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  221 (281)
T 4PLS_B          166 IDAGALPALVQLLS-SPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLS  221 (281)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHCChHHHHHHHhc-CCcHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHcc
Confidence            33456677777776 5567788888888888876422 2222222 56666666664


No 193
>5MFO_F YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: CA, EDO; 1.3A {synthetic construct}
Probab=95.88  E-value=5e-05  Score=65.80  Aligned_cols=112  Identities=26%  Similarity=0.298  Sum_probs=74.3  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.+..++..++.++..++.........+
T Consensus        89 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  168 (202)
T 5MFO_F           89 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAV  168 (202)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHhcChHHHHHHH
Confidence            45556666666677788888999988876543333333344677777777777777888889999988886543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ...++++.+..++. ..++.++..++.++..++
T Consensus       169 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~  200 (202)
T 5MFO_F          169 KEAGAEPALEQLQS-SPNEKIQKEAQEALEKIQ  200 (202)
T ss_dssp             HHTTHHHHHHTTTT-CSSHHHHHHHHHHHHHHH
T ss_pred             HHCCHHHHHHHHHc-CCCHHHHHHHHHHHHHHH
Confidence            33456666777775 446677777777776654


No 194
>2RU4_A Armadillo Repeat Protein, N-terminal fragment; solenoid repeat, Armadillo repeat motif; NMR {synthetic construct}
Probab=95.88  E-value=5.2e-05  Score=59.81  Aligned_cols=110  Identities=25%  Similarity=0.264  Sum_probs=70.0  Template_Neff=12.800

Q NP_000290.2     248 PKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRR  327 (747)
Q Consensus       248 ~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~  327 (747)
                      +.+...+...+..++..++.++..++.........+...+.++.+...+.+.++.++..++.++.+++.........+..
T Consensus         4 ~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~   83 (115)
T 2RU4_A            4 PQMTQQLNSDDMQEQLSATRKFSQILSDGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVID   83 (115)
T ss_dssp             CCCCCCCCCCCCCCCSCCCCCCCCCCCSCTTHHHHHCCSSSHHHHHHGGGSSCHHHHHHHHHHHHHHHTTCHHHHHHHHT
T ss_pred             HHHHHhhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCchHHHHHHH
Confidence            34455555556677888888888887654333333444456777777777667778888888888887554333333333


Q NP_000290.2     328 QNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       328 ~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      .+.++.+...+. ..++.++..++.++.+++
T Consensus        84 ~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~  113 (115)
T 2RU4_A           84 AGALPALVQLLS-SPNEQILQEALWALSNIA  113 (115)
T ss_dssp             TTHHHHHHHGGG-SSCHHHHHHHHHHHHHHH
T ss_pred             CCcHHHHHHHhc-CCCHHHHHHHHHHHHHHh
Confidence            456666666665 445667777777776654


No 195
>5AEI_B DESIGNED ARMADILLO REPEAT PROTEIN YIIIM5AII; DE NOVO PROTEIN, PROTEIN-PEPTIDE COMPLEX; HET: CA, ACT; 1.83A {SYNTHETIC CONSTRUCT}
Probab=95.87  E-value=5.1e-05  Score=69.48  Aligned_cols=114  Identities=26%  Similarity=0.296  Sum_probs=74.7  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.+..++..++.++..++.........+
T Consensus        47 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  126 (286)
T 5AEI_B           47 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV  126 (286)
T ss_dssp             CHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHHTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcChHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHH
Confidence            45556666666677888889999988876544333333344567777777777777888889999988876433332233


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++..++..
T Consensus       127 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  160 (286)
T 5AEI_B          127 IDAGALPALVQLLS-SPNEQILQEALWALSNIASG  160 (286)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTS
T ss_pred             HhCCHHHHHHHHcc-CCCHHHHHHHHHHHHHHHcC
Confidence            33446666666665 44566777777777776653


No 196
>5MFD_C YIIIM''6AII, Capsid decoration protein,pD_(KR)5; Designed armadillo repeat protein, peptide; HET: CA; 2.3A {synthetic construct}
Probab=95.87  E-value=5.1e-05  Score=70.81  Aligned_cols=157  Identities=20%  Similarity=0.303  Sum_probs=116.5  Template_Neff=13.300

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      +.++++.+..++. +.++.++..++.+|.+++.....     ....+...++++.+..++.+.++.++..++.+|.+++.
T Consensus       128 ~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~  201 (328)
T 5MFD_C          128 DAGALPALVQLLS-SPNEQILQEALWTLGNIASGGNE-----QIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIAS  201 (328)
T ss_dssp             HTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHHT
T ss_pred             HCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHH-----HHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHHc
Confidence            4456777888887 46777888899999998864332     22333456788888888888888899999999999987


Q NP_000290.2     625 H-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAE  702 (747)
Q Consensus       625 ~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~  702 (747)
                      . ... ..+...++++.+..++.+      .++.++..++.+|.+++...+.....+...++++.+..++.+. ++.++.
T Consensus       202 ~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~  274 (328)
T 5MFD_C          202 GGNEQIQAVIDAGALPALVQLLSS------PNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSP-NEQILQ  274 (328)
T ss_dssp             SCHHHHHHHHHTTCHHHHHHGGGC------SCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGCS-CHHHHH
T ss_pred             CCHHHHHHHHHCChHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHhcCC-CHHHHH
Confidence            6 222 233445677888888766      3677889999999999865555545555566788888888766 788899


Q NP_000290.2     703 AARLLLSDMWSS  714 (747)
Q Consensus       703 aAL~aLsnL~~~  714 (747)
                      .++.+|.+++..
T Consensus       275 ~a~~~l~~l~~~  286 (328)
T 5MFD_C          275 EALWTLGNIASG  286 (328)
T ss_dssp             HHHHHHHHHHTS
T ss_pred             HHHHHHHHHhCC
Confidence            999999999865


No 197
>5MFO_E YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: EDO, CA; 1.3A {synthetic construct}
Probab=95.87  E-value=5.2e-05  Score=65.68  Aligned_cols=112  Identities=26%  Similarity=0.298  Sum_probs=74.3  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.+..++..++.++..++.........+
T Consensus        89 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  168 (202)
T 5MFO_E           89 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAV  168 (202)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCHHHHHHHH
Confidence            45556666666667788888899988876543333333344677777777777777888889999988886543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ...++++.+..++. ..++.++..++.++..++
T Consensus       169 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~  200 (202)
T 5MFO_E          169 KEAGAEPALEQLQS-SPNEKIQKEAQEALEKIQ  200 (202)
T ss_dssp             HHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHC
T ss_pred             HHCCHHHHHHHHHc-CCCHHHHHHHHHHHHHHH
Confidence            33456666777775 446677777777776654


No 198
>5D5K_C Importin subunit alpha-1, Poly [ADP-ribose]; PARP-2 NLS, PARP-2, poly(ADP-ribose)polymerase-2, Importin; 1.9A {Mus musculus}
Probab=95.85  E-value=5.5e-05  Score=74.91  Aligned_cols=158  Identities=19%  Similarity=0.271  Sum_probs=114.4  Template_Neff=13.100

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDA-----TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASL  618 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~e-----Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~a  618 (747)
                      .+.++++.++.++.. .+..     ++..++.+|.+++.....     ........++++.+..++.+.++.++..++.+
T Consensus       138 ~~~~~~~~l~~~l~~-~~~~~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~  211 (466)
T 5D5K_C          138 IKHGAIDPLLALLAV-PDLSTLACGYLRNLTWTLSNLCRNKNP-----APPLDAVEQILPTLVRLLHHNDPEVLADSCWA  211 (466)
T ss_dssp             HHTTCHHHHHHTTCS-SCGGGSCHHHHHHHHHHHHHHSCCCSS-----CCCHHHHHHHHHHHHHHTTSSCHHHHHHHHHH
T ss_pred             HHCCcHHHHHHHhhC-CCcccccHHHHHHHHHHHHHHHcCCCC-----CCChHHHHHHHHHHHHHHcCCCHHHHHHHHHH
Confidence            355667777777763 3333     677888888888765322     11121225678888888888888899999999


Q NP_000290.2     619 LSNMSRHPL-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA  696 (747)
Q Consensus       619 LsnLa~~~e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~  696 (747)
                      |.+++.... . ..+...++++.+..++.+      .++.++..++.+|.+++...+.....+...++++.+..++.+. 
T Consensus       212 l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-  284 (466)
T 5D5K_C          212 ISYLTDGPNERIEMVVKKGVVPQLVKLLGA------TELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNP-  284 (466)
T ss_dssp             HHHHTSSCHHHHHHHHTTTCHHHHHHHHTC------SCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTGGGGHHHHTTCS-
T ss_pred             HHHHhcCCchHHHHHHHCChHHHHHHHhcC------CCchHHHHHHHHHHHHhcCCHHHHHHHHccChhHhHHHHhhCC-
Confidence            999987632 2 233455677888888876      3678889999999999876455555566667888888888766 


Q NP_000290.2     697 SPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       697 d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.++..++.+|.+++..
T Consensus       285 ~~~v~~~a~~~l~~l~~~  302 (466)
T 5D5K_C          285 KTNIQKEATWTMSNITAG  302 (466)
T ss_dssp             SHHHHHHHHHHHHHHTTS
T ss_pred             CHHHHHHHHHHHHHHHcC
Confidence            788899999999998875


No 199
>1XQS_B HSPBP1 protein, Heat shock 70; armadillo repeat, superhelical twist, CHAPERONE; HET: AMP; 2.9A {Homo sapiens} SCOP: a.118.1.21
Probab=95.84  E-value=5.9e-05  Score=71.37  Aligned_cols=116  Identities=18%  Similarity=0.237  Sum_probs=80.5  Template_Neff=11.900

Q NP_000290.2     246 TIPKAVQYLSSQ-DEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ss-d~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+..++... +..++..++.++.+++.........+...+.++.+..++...+..++..++.++.+++.........
T Consensus       109 ~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~  188 (280)
T 1XQS_B          109 ALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQQQVQKLKVKSAFLLQNLLVGHPEHKGT  188 (280)
T ss_dssp             HHHHHHHHHHSCSCHHHHHHHHHHHHHTTSSCHHHHHHHHTTTHHHHHHHHHTSSCHHHHHHHHHHHHHHHHHCGGGHHH
T ss_pred             HHHHHHHHhccCCCHHHHHHHHHHHHHHHhcCHHHHHHHHHCCHHHHHHHHhhCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            455566666654 6778888999999988654433334444567777888777667778888999999888654423333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~  362 (747)
                      +...++++.+..++. ..++.++..++.++.+++....
T Consensus       189 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~  225 (280)
T 1XQS_B          189 LCSMGMVQQLVALVR-TEHSPFHEHVLGALCSLVTDFP  225 (280)
T ss_dssp             HHTTTHHHHHHHHHT-SSCCTTHHHHHHHTTTSSTTCH
T ss_pred             HHhCCHHHHHHHHHc-CCCcHHHHHHHHHHHHHHhcCH
Confidence            444467777777776 5567788888999998887543


No 200
>4UAF_B Importin alpha 1 import receptor; importin karyopherin complex NLS, PROTEIN; HET: PO4; 1.698A {Mus musculus}
Probab=95.82  E-value=5.9e-05  Score=74.70  Aligned_cols=158  Identities=19%  Similarity=0.271  Sum_probs=114.6  Template_Neff=13.100

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDA-----TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASL  618 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~e-----Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~a  618 (747)
                      .+.++++.++.++.. .+..     ++..++.+|.+++.....     ........++++.+..++.+.++.++..++.+
T Consensus       138 ~~~~~~~~l~~~l~~-~~~~~~~~~~~~~~~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~  211 (466)
T 4UAF_B          138 IKHGAIDPLLALLAV-PDLSTLACGYLRNLTWTLSNLCRNKNP-----APPLDAVEQILPTLVRLLHHNDPEVLADSCWA  211 (466)
T ss_pred             HHCCcHHHHHHHhhC-CCcccccHHHHHHHHHHHHHHHcCCCC-----CCChhHHHHHHHHHHHHHcCCCHHHHHHHHHH
Confidence            355667777777763 3333     677888888888865332     11121225678888888888888999999999


Q NP_000290.2     619 LSNMSRHPL-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA  696 (747)
Q Consensus       619 LsnLa~~~e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~  696 (747)
                      |.+++.... . ..+...++++.+..++.+      .++.++..++.+|.+++...+.....+...++++.+..++.+. 
T Consensus       212 l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-  284 (466)
T 4UAF_B          212 ISYLTDGPNERIEMVVKKGVVPQLVKLLGA------TELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNP-  284 (466)
T ss_pred             HHHHhcCCcHHHHHHHHCChHHHHHHHhcC------CChhHHHHHHHHHHHHhcCCHHHHHHHhccCHHHHHHHHhcCC-
Confidence            999987632 2 233455678888888876      3678889999999999876455555566667888888888766 


Q NP_000290.2     697 SPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       697 d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.++..++.+|.+++..
T Consensus       285 ~~~v~~~a~~~l~~l~~~  302 (466)
T 4UAF_B          285 KTNIQKEATWTMSNITAG  302 (466)
T ss_pred             CHHHHHHHHHHHHHHhcC
Confidence            788899999999999875


No 201
>1XQR_A HspBP1 protein; armadillo repeat, superhelical twist, CHAPERONE; HET: MSE; 2.1A {Homo sapiens} SCOP: a.118.1.21
Probab=95.82  E-value=6.4e-05  Score=72.71  Aligned_cols=116  Identities=18%  Similarity=0.237  Sum_probs=81.0  Template_Neff=11.300

Q NP_000290.2     246 TIPKAVQYLSSQ-DEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ss-d~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+..++... ++.++..++.++.+++.........+...++++.+...+...+..++..++.++.+++.........
T Consensus       125 ~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~  204 (296)
T 1XQR_A          125 ALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQQQVQKLKVKSAFLLQNLLVGHPEHKGT  204 (296)
T ss_dssp             HHHHHHHHHHHCSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHSSCHHHHHHHHHHHHHHHHHCGGGHHH
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhhCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            455566666654 6778889999999998754433334444567777887777667788888999999888754433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~  362 (747)
                      +...++++.+..++. ..++.++..++.+|.+++....
T Consensus       205 ~~~~~~i~~L~~ll~-~~~~~~~~~a~~~L~~l~~~~~  241 (296)
T 1XQR_A          205 LCSMGMVQQLVALVR-TEHSPFHEHVLGALCSLVTDFP  241 (296)
T ss_dssp             HHHTTHHHHHHHHHT-SCCSTHHHHHHHHHHHHHTTCH
T ss_pred             HHhCCHHHHHHHHHc-CCChHHHHHHHHHHHHHHhcCH
Confidence            444567777777776 4566788888899988887543


No 202
>6CRI_R Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=95.81  E-value=6.2e-05  Score=78.24  Aligned_cols=151  Identities=10%  Similarity=0.021  Sum_probs=91.7  Template_Neff=12.500

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ---SGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~---s~d~eVr~~AL~aLsnLa  623 (747)
                      ..++.|+.++. +.+..++..++.++..+....+.          ....+++.+...+.   ..+..++ .++++|+.+.
T Consensus       414 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~----------~~~~~~~~l~~~l~~~~~~~~~~r-~a~~~l~~~~  481 (585)
T 6CRI_R          414 WHIDTIMRVLT-TAGSYVRDDAVPNLIQLITNSVE----------MHAYTVQRLYKAILGDYSQQPLVQ-VAAWCIGEYG  481 (585)
T ss_pred             HHHHHHHHHHH-HhccccCccHHHHHHHHHhcCch----------HHHHHHHHHHHHHHCCCCCHHHHH-HHHHHHHHHH
Confidence            35566666666 35566777777777777653211          11234555666653   3344556 7888888877


Q NP_000290.2     624 RHPLLH--------RVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR  693 (747)
Q Consensus       624 ~~~e~~--------~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~  693 (747)
                      ......        ......+++.|..++  .+      .+..++..++.+|..+....+.     ....++..+..++.
T Consensus       482 ~~~~~~~~~~~~~~~~~~~~~~~~L~~~l~~~~------~~~~vr~~a~~al~~l~~~~~~-----~~~~~~~~l~~~~~  550 (585)
T 6CRI_R          482 DLLVSGQCEEEEPIQVTEDEVLDILESVLISNM------STSVTRGYALTAIMKLSTRFTC-----TVNRIKKVVSIYGS  550 (585)
T ss_pred             HHhcCCCCCCCCCCCCCHHHHHHHHHHHhcccC------CCHHHHHHHHHHHHHHHhcCCc-----hHHHHHHHHHHHcc
Confidence            642110        111234566666666  33      3567888999999998875332     22234555666666


Q NP_000290.2     694 SSASPKAAEAARLLLSDMWSSKELQGVL  721 (747)
Q Consensus       694 s~~d~eVr~aAL~aLsnL~~~~~~~~~~  721 (747)
                      +. ++.++..++.++..+..+......+
T Consensus       551 ~~-~~~vr~~a~~~l~~l~~~~~~~~~l  577 (585)
T 6CRI_R          551 SI-DVELQQRAVEYNALFKKYDHMRSAL  577 (585)
T ss_pred             CC-CHHHHHHHHHHHHHhhhHHHHHHHH
Confidence            65 7889999999999988765544443


No 203
>6SA8_A ring-like DARPin-Armadillo fusion H83_D01, LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG; protein fusion, DARPin, Armadillo, shared; 2.4A {synthetic construct}
Probab=95.78  E-value=6.8e-05  Score=80.44  Aligned_cols=136  Identities=26%  Similarity=0.298  Sum_probs=92.6  Template_Neff=11.900

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.+|.+++...+.....+...++++.+..++.+.++.++..++.++..++.........
T Consensus       262 ~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~L~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  341 (671)
T 6SA8_A          262 GALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQA  341 (671)
T ss_dssp             TCHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             CHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCcHHHHHHHHhChHHHHHHHhcCCcHHHHHHHHHHHHHHhcCCcHHHHH
Confidence            34556666666677788889999999887654333334444567788888888777888889999999987654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST-DELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~-~~~~~~Lve-giLe~Lv~LL~~  381 (747)
                      +...++++.+...+. ..++.++..++.++..++.. ......+.. ++++.|+.++..
T Consensus       342 ~~~~~~l~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~  399 (671)
T 6SA8_A          342 VIDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSS  399 (671)
T ss_dssp             HHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGC
T ss_pred             HHhcChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCcHHHHHHHHcCcHHHHHHHhcC
Confidence            334456777777776 55677888899999998873 332333333 677777776653


No 204
>5WBJ_A Regulatory-associated protein of TOR 1,Eukaryotic; Raptor, TOS, PROTEIN BINDING; 3.0A {Arabidopsis thaliana}
Probab=95.77  E-value=8.1e-05  Score=89.51  Aligned_cols=168  Identities=12%  Similarity=0.072  Sum_probs=120.9  Template_Neff=8.700

Q NP_000290.2     541 GWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG--NSDVVRSGASL  618 (747)
Q Consensus       541 ~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~--d~eVr~~AL~a  618 (747)
                      ..+...|+++.++.+|. +..++++..++.++.+++..++.     .+..+.+.+++..|+.+|...  .+.++..++.+
T Consensus       500 ~~~~~~gi~p~ll~lL~-s~~~~lr~~a~~i~a~i~~~d~~-----~q~~l~~~~~l~~ll~~L~~~~~~~~~r~~a~~~  573 (1287)
T 5WBJ_A          500 DLALSVGIFPYVLKLLQ-TTTNELRQILVFIWTKILALDKS-----CQIDLVKDGGHTYFIRFLDSSGAFPEQRAMAAFV  573 (1287)
T ss_dssp             HHHHHHTCHHHHHHGGG-CCCHHHHHHHHHHHHHHHHHCGG-----GHHHHHHTTCHHHHHHHHHCSSCCHHHHHHHHHH
T ss_pred             HHHHHCCcHHHHHHHHc-CCCHHHHHHHHHHHHHHHccCHH-----HHHHHHHcCCeeeEEEeecCCCCCHHHHHHHHHH
Confidence            33457789999999998 47788899999999999876443     344556677888899988743  35567788999


Q NP_000290.2     619 LSNMSRH-PLL-HRVMGNQVFPEVTRLLTSHTG-NTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSS  695 (747)
Q Consensus       619 LsnLa~~-~e~-~~ll~~giI~~Ll~LL~s~s~-~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~  695 (747)
                      |+.++.. ... ..+...+++..+...|..... ....++.++..++.+|..|+...+.........+++..|+.+|.+.
T Consensus       574 Ls~l~~~~~~~~~~~~~~~~l~~l~~~L~~~~~~~~~~~~~lr~~a~~~L~~L~~~~~~~~~~~~~~~~~~~L~~lL~~~  653 (1287)
T 5WBJ_A          574 LAVIVDGHRRGQEACLEANLIGVCLGHLEASRPSDPQPEPLFLQWLCLCLGKLWEDFMEAQIMGREANAFEKLAPLLSEP  653 (1287)
T ss_dssp             HHHHHTTCHHHHHHHHHTTHHHHHHHHCC---------CHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHGGGGGCS
T ss_pred             HHHHHcCCHhHHHHHHHCcHHHHHHHHHHhcCCCCCCCCHHHHHHHHHHHHHHHhccHHHHHHHHHcCHHHHHHHHhcCC
Confidence            9999876 222 233444677777777761000 0003678899999999999877555555556667788899999877


Q NP_000290.2     696 ASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       696 ~d~eVr~aAL~aLsnL~~~~  715 (747)
                       ++.++.+++.+|+.++...
T Consensus       654 -~~~VRaaal~aL~~li~~~  672 (1287)
T 5WBJ_A          654 -QPEVRAAAVFALGTLLDIG  672 (1287)
T ss_dssp             -CHHHHHHHHHHHHHTCC--
T ss_pred             -CHHHHHHHHHHHHHHHhcC
Confidence             8899999999999998764


No 205
>5Z8H_A Adenomatous polyposis coli protein, Peptide; APC, inhibitor, PROTEIN BINDING-INHIBITOR complex; HET: PHQ, GOL; 1.79A {Homo sapiens}
Probab=95.74  E-value=7.4e-05  Score=71.65  Aligned_cols=115  Identities=17%  Similarity=0.172  Sum_probs=76.4  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQD----EKYQAIGAYYIQHTCF---QDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS  318 (747)
Q Consensus       246 iL~~Ll~lL~ssd----~eVr~sAL~aLsnLs~---~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~  318 (747)
                      +++.+..++...+    ..++..++.++.++..   ........+...++++.+..++...++.++..++.++.+++...
T Consensus       210 ~~~~l~~~l~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~  289 (339)
T 5Z8H_A          210 ALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARN  289 (339)
T ss_pred             hHHHHHHHhcCCCCCCCHHHHHHHHHHHHHHHHhhccCHHHHHHHHHCCHHHHHHHHHhCCCHHHHHHHHHHHHHHhCCC
Confidence            4445555554332    5677778888887752   22223333334467777788787777788889999999988744


Q NP_000290.2     319 TTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD  361 (747)
Q Consensus       319 ~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~  361 (747)
                      +.....+...++++.+..++. ..++.++..++.++.+++...
T Consensus       290 ~~~~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~  331 (339)
T 5Z8H_A          290 PKDQEALWDMGAVSMLKNLIH-SKHKMIAMGSAAALRNLMANR  331 (339)
T ss_pred             HHHHHHHHHCCcHHHHHHHhh-CCCHHHHHHHHHHHHHHHcCC
Confidence            443344444567788888886 556778888999998888643


No 206
>5WBK_A Regulatory-associated protein of TOR 1,Ribosomal; Raptor, TOS, PROTEIN BINDING; 3.11A {Arabidopsis thaliana}
Probab=95.72  E-value=9.2e-05  Score=89.00  Aligned_cols=168  Identities=12%  Similarity=0.072  Sum_probs=120.7  Template_Neff=8.700

Q NP_000290.2     541 GWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG--NSDVVRSGASL  618 (747)
Q Consensus       541 ~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~--d~eVr~~AL~a  618 (747)
                      ..+...|+++.|+++|. +..++++..++.++.+++..++.     .+..+.+.+++..|+.+|...  .+.++..++.+
T Consensus       500 ~~~l~~Gi~p~ll~lL~-s~~~~lr~~a~~i~a~i~~~d~~-----~q~~l~~~~~l~~ll~~L~~~~~~~~~r~~a~~~  573 (1287)
T 5WBK_A          500 DLALSVGIFPYVLKLLQ-TTTNELRQILVFIWTKILALDKS-----CQIDLVKDGGHTYFIRFLDSSGAFPEQRAMAAFV  573 (1287)
T ss_dssp             HHHHHHTCHHHHHHGGG-CCCHHHHHHHHHHHHHHHHHCGG-----GHHHHHHTTTHHHHHHHHHSSCCCHHHHHHHHHH
T ss_pred             HHHHHCCcHHHHHHHHc-CCCHHHHHHHHHHHHHHHccCHH-----HHHHHHHcCCeeeEEEeecCCCCCHHHHHHHHHH
Confidence            33457789999999998 46778899999999999876443     344456677888899988743  35567788899


Q NP_000290.2     619 LSNMSRH-PLL-HRVMGNQVFPEVTRLLTSHTG-NTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSS  695 (747)
Q Consensus       619 LsnLa~~-~e~-~~ll~~giI~~Ll~LL~s~s~-~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~  695 (747)
                      |+.++.. ... ..+...+++..+...|..... ....++.++..++.+|+.|+...+.........+++..|+.+|.+.
T Consensus       574 Ls~l~~~~~~~~~~~~~~~~l~~l~~~L~~~~~~~~~~~~~lr~~a~~~L~~L~~~~~~~~~~~~~~~~~~~L~~lL~~~  653 (1287)
T 5WBK_A          574 LAVIVDGHRRGQEACLEANLIGVCLGHLEASRPSDPQPEPLFLQWLCLCLGKLWEDFMEAQIMGREANAFEKLAPLLSEP  653 (1287)
T ss_dssp             HHHHHTTCHHHHHHHHHTTHHHHHHHHCC---------CHHHHHHHHHHHHHHHTTCHHHHHHHHTTTHHHHHGGGGGCS
T ss_pred             HHHHHcCCHhHHHHHHHCcHHHHHHHHHHhcCCCCCCCCHHHHHHHHHHHHHHHcccHHHHHHHHHCCHHHHHHHHhcCC
Confidence            9999876 222 233444677777777761000 0003678899999999999876555555556667788899999877


Q NP_000290.2     696 ASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       696 ~d~eVr~aAL~aLsnL~~~~  715 (747)
                       ++.+|.+++.+|+.++...
T Consensus       654 -~~~VRaaal~AL~~li~~~  672 (1287)
T 5WBK_A          654 -QPEVRAAAVFALGTLLDIG  672 (1287)
T ss_dssp             -CHHHHHHHHHHHHHHCC--
T ss_pred             -CHHHHHHHHHHHHHHHhcC
Confidence             8899999999999998764


No 207
>6SA6_A DARPin-Armadillo fusion A5; protein fusion, DARPin, Armadillo, shared; HET: EDO; 1.6A {synthetic construct}
Probab=95.69  E-value=8.4e-05  Score=73.16  Aligned_cols=135  Identities=25%  Similarity=0.260  Sum_probs=92.1  Template_Neff=12.400

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+..++.+.++.++..++.+|.+++.........+...++++.+..++...++.++..++.+|..++.........
T Consensus       241 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~  320 (397)
T 6SA6_A          241 GALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQA  320 (397)
T ss_dssp             THHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             CcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCcHHHHHHHHhCChHHHHHHHhcCCcHHHHHHHHHHHHHHhcCcHHHHHH
Confidence            34566666777777888889999999987654333333444467777888887777788888899998887654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST-DELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~-~~~~~~Lve-giLe~Lv~LL~  380 (747)
                      +...++++.+..++. ..++.++..++.++..++.. ......+.. ++++.|..++.
T Consensus       321 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  377 (397)
T 6SA6_A          321 VIDAGALPALVQLLS-SPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQS  377 (397)
T ss_dssp             HHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHhcChHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCCHHHHHHHHHcCchHHHHHHHh
Confidence            444567777888776 55678888899999998874 333333333 67777777664


No 208
>2W3C_A GENERAL VESICULAR TRANSPORT FACTOR P115; MEMBRANE VESICLE TETHERING, ARMADILLO FOLD; HET: PEG; 2.22A {HOMO SAPIENS}
Probab=95.59  E-value=0.00012  Score=79.14  Aligned_cols=136  Identities=15%  Similarity=0.146  Sum_probs=91.0  Template_Neff=10.400

Q NP_000290.2     246 TIPKAVQYLSSQ--DEKYQAIGAYYIQHTCFQDES-----------------AKQQVY-QLGGICKLVDLLRSPNQNVQQ  305 (747)
Q Consensus       246 iL~~Ll~lL~ss--d~eVr~sAL~aLsnLs~~~~~-----------------~~~~li-~~~IL~~Ll~lL~s~d~eVr~  305 (747)
                      .++.++..+.+.  +..+...++.+|..++.....                 ....+. ..+.++.++.++.+.+..++.
T Consensus         9 ~l~~Li~~L~~~~~~~~~~~~al~~L~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~L~~ll~~~~~~v~~   88 (577)
T 2W3C_A            9 AMEHLIHVLQTDRSDSEIIGYALDTLYNIISNEEEEEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVRW   88 (577)
T ss_dssp             TTHHHHHHHHHCTTCHHHHHHHHHHHHHHHHC------------------CHHHHHHHHSTHHHHHHHHHTTCCCHHHHH
T ss_pred             hHHHHHHHHhhCCCcHHHHHHHHHHHHHHhCCCchhhhhhccccccHHHHHHHHHHHHhcCchHHHHHHHccCCCHHHHH
Confidence            345566666543  456778888888888765431                 122233 456777788888777788899


Q NP_000290.2     306 AAAGALRNLVFRST-TNKLETR-RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       306 ~AL~aLs~La~~~~-~~~~~ll-~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~~  381 (747)
                      .++.+|..++...+ .....+. ..+.++.++.++. ..+..++..++.+|.+++... .....+.. ++++.|+.++..
T Consensus        89 ~a~~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~-~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~g~~~~L~~ll~~  167 (577)
T 2W3C_A           89 PGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLA-DSREVIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIISE  167 (577)
T ss_dssp             HHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHHGGGG-CSSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhchHHHHHHHHhCCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHcCCHHHHHHHHHHH
Confidence            99999999886543 2222333 2467888888886 556788999999999998743 33333333 889999988875


Q NP_000290.2     382 P  382 (747)
Q Consensus       382 ~  382 (747)
                      .
T Consensus       168 ~  168 (577)
T 2W3C_A          168 E  168 (577)
T ss_dssp             T
T ss_pred             h
Confidence            3


No 209
>6CRI_I Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=95.58  E-value=0.0001  Score=74.75  Aligned_cols=106  Identities=11%  Similarity=0.025  Sum_probs=69.8  Template_Neff=13.200

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.+..++..++.++..+....       ....+++.+...+.+.++.++..++.++..+.........
T Consensus        72 ~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~-------~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~~~~~  144 (570)
T 6CRI_I           72 IMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDK-------ITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLVE  144 (570)
T ss_dssp             GTTHHHHHHHTSSSCHHHHHHHHHHHHHCCCTT-------TTTTSHHHHHHHHTCSSHHHHHHHHHHHHHHHHHCHHHHH
T ss_pred             HHHHHHHHHHcCCCCHHHHHHHHHHHccCChhH-------HHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHHhChhhhh
Confidence            344555666666677778888888887775321       1123556666667777788888899988888754332211


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                         ...+++.+...+. +.++.++..++.++..+...
T Consensus       145 ---~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~  177 (570)
T 6CRI_I          145 ---DQGFLDTLKDLIS-DSNPMVVANAVAALSEIAES  177 (570)
T ss_dssp             ---HHTHHHHHHHHHT-SSSHHHHHHHHHHHHHHHHH
T ss_pred             ---ccchHHHHHHHhc-CCCHHHHHHHHHHHHHHHhh
Confidence               1345666677776 56778888899888888764


No 210
>1QBK_B STRUCTURE OF THE KARYOPHERIN BETA2-RAN; HEAT REPEATS, NUCLEAR TRANSPORT PROTEIN; HET: GNP; 3.0A {Homo sapiens} SCOP: a.118.1.1
Probab=95.57  E-value=0.00011  Score=79.31  Aligned_cols=157  Identities=12%  Similarity=0.081  Sum_probs=97.3  Template_Neff=13.200

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.+...+. +.++.++..++.+|..++...+.     ....+ -..+++.+...+.+.+..++..++.++..++...
T Consensus       667 ~~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~  739 (890)
T 1QBK_B          667 NILTLMYQCMQ-DKMPEVRQSSFALLGDLTKACFQ-----HVKPC-IADFMPILGTNLNPEFISVCNNATWAIGEISIQM  739 (890)
T ss_pred             hHHHHHHHHHh-CCCHHHHHHHHHHHHHHHHHhHH-----hHHHH-HHHHHHHHHhhcCcccHHHHHHHHHHHHHHHHHc
Confidence            35566666666 36778888899999988764321     11111 1346667777777777889999999999988652


Q NP_000290.2     627 -LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 -e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                       .........+++.+...+.+.    ..+..++..++.+|+.++...+....... ..++..++..+....++.++..++
T Consensus       740 ~~~~~~~~~~i~~~l~~~l~~~----~~~~~~r~~a~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~~~~~~~~~~~  814 (890)
T 1QBK_B          740 GIEMQPYIPMVLHQLVEIINRP----NTPKTLLENTAITIGRLGYVCPQEVAPML-QQFIRPWCTSLRNIRDNEEKDSAF  814 (890)
T ss_pred             CccccchHHHHHHHHHHHHcCC----CCCccHHHHHHHHHHHHHhhCHHhHHHHH-HHhHHHHHHHHhcCCChHHHHHHH
Confidence             211112234566677766541    01567888999999998875332211111 234555666555432567788888


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .+|..+....
T Consensus       815 ~~l~~l~~~~  824 (890)
T 1QBK_B          815 RGICTMISVN  824 (890)
T ss_pred             HHHHHHHhhC
Confidence            8888776543


No 211
>4P6Z_G BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=95.56  E-value=0.00012  Score=77.66  Aligned_cols=151  Identities=10%  Similarity=0.027  Sum_probs=89.9  Template_Neff=12.000

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ---SGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~---s~d~eVr~~AL~aLsnLa  623 (747)
                      ..++.|+.++. +.++.++..++.+|..+....+.          ....+++.+...+.   ..+..++ .++++|+.+.
T Consensus       431 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~----------~~~~~~~~l~~~l~~~~~~~~~~r-~a~~~l~~~~  498 (627)
T 4P6Z_G          431 WHIDTIMRVLT-TAGSYVRDDAVPNLIQLITNSVE----------MHAYTVQRLYKAILGDYSQQPLVQ-VAAWCIGEYG  498 (627)
T ss_dssp             HHHHHHHHHHH-HTGGGSCGGGHHHHHHHHHSCTT----------TTHHHHHHHHHHHHHCCCSHHHHH-HHHHHHHHTH
T ss_pred             HHHHHHHHHHH-hhccccCcchHHHHHHHHhcCch----------HHHHHHHHHHHHHHcCCCCHHHHH-HHHHHHHHHH
Confidence            35566666665 35566677777777776643211          01234455555553   2334555 7778887776


Q NP_000290.2     624 RHPLL-H-------RVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR  693 (747)
Q Consensus       624 ~~~e~-~-------~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~  693 (747)
                      ..... .       ......+++.|..++  .+      .++.++..++.+|..+....+.     ....++..|..++.
T Consensus       499 ~~~~~~~~~~~~~~~~~~~~~~~~L~~~l~~~~------~~~~vr~~a~~~L~~l~~~~~~-----~~~~~~~~l~~~~~  567 (627)
T 4P6Z_G          499 DLLVSGQCEEEEPIQVTEDEVLDILESVLISNM------STSVTRGYALTAIMKLSTRFTC-----TVNRIKKVVSIYGS  567 (627)
T ss_dssp             HHHHSCCCTTSCCCCCCSHHHHHHHHHHHHCTT------CCHHHHHHHHHHHHHHHHHCCS-----CHHHHHHHHHHGGG
T ss_pred             HHhccCCCCCCCCCCCCHHHHHHHHHHHHcccC------CCHHHHHHHHHHHHHHHhhccc-----hHHHHHHHHHHHcc
Confidence            54111 0       011124566666666  33      3567889999999998865332     22234566666666


Q NP_000290.2     694 SSASPKAAEAARLLLSDMWSSKELQGVL  721 (747)
Q Consensus       694 s~~d~eVr~aAL~aLsnL~~~~~~~~~~  721 (747)
                      +. +..++..++.++..+..+......|
T Consensus       568 ~~-~~~vr~~a~~~l~~l~~~~~~~~~l  594 (627)
T 4P6Z_G          568 SI-DVELQQRAVEYNALFKKYDHMRSAL  594 (627)
T ss_dssp             CS-CHHHHHHHHHHHHHHHHCTTHHHHH
T ss_pred             CC-CHHHHHHHHHHHHHhhhHHHHHHHH
Confidence            65 7889999999999988764444443


No 212
>5MFI_B YIII(Dq.V2)4CqI, (KR)4; Designed armadillo repeat protein, peptide; 1.45A {synthetic construct}
Probab=95.46  E-value=0.00014  Score=65.05  Aligned_cols=112  Identities=20%  Similarity=0.227  Sum_probs=75.6  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++.+++...+.....+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus       131 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  210 (243)
T 5MFI_B          131 ALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKL  210 (243)
T ss_dssp             CHHHHHHTTTSSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHGGGCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666667788888889888876544333333444577778888877778888899999998886444333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ...++++.+..++. ..++.++..++.++..++
T Consensus       211 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~  242 (243)
T 5MFI_B          211 EEAGAEPALEKLQS-SPNEEVQKNAQAALEALN  242 (243)
T ss_dssp             HHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHC
T ss_pred             HHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHhc
Confidence            33456667777775 456677777777777654


No 213
>5MFJ_B YIII(Dq.V2)4CqI, (KR)5; Designed armadillo repeat protein, peptide; 1.53A {synthetic construct}
Probab=95.46  E-value=0.00014  Score=65.05  Aligned_cols=112  Identities=20%  Similarity=0.227  Sum_probs=75.6  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++.+++...+.....+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus       131 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  210 (243)
T 5MFJ_B          131 ALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKL  210 (243)
T ss_dssp             CHHHHHHTTTSSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHGGGCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666667788888889888876544333333444577778888877778888899999998886444333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ...++++.+..++. ..++.++..++.++..++
T Consensus       211 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~  242 (243)
T 5MFJ_B          211 EEAGAEPALEKLQS-SPNEEVQKNAQAALEALN  242 (243)
T ss_dssp             HHTTHHHHHHHTSS-CSCHHHHHHHHHHHHHHC
T ss_pred             HHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHhc
Confidence            33456667777775 456677777777777654


No 214
>5EWP_B Uncharacterized protein; translocation and attachment of rhoptries; 1.8A {Plasmodium falciparum Santa Lucia}
Probab=95.43  E-value=0.00015  Score=67.32  Aligned_cols=134  Identities=16%  Similarity=0.127  Sum_probs=89.1  Template_Neff=11.800

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+..++...+..++..++.++.+++.........+...+.++.++.++...+..++..++.++.+++.........+
T Consensus        87 ~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~  166 (252)
T 5EWP_B           87 GIAVFINLLKSHELDRVHAAVVALSFLSVDNVKNCICMFESGALPYLISGMKSNIDGMKAACAQTCRNIFVLDKKYKKEF  166 (252)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTTCHHHHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHHH
T ss_pred             cHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHhhCCCHHHHHHHHHHHHHHHhcCHHHHHHH
Confidence            45556666666667788889999999887544444445555677888888877677888999999999876533333344


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNA-------EIQKQLTGLLWNLSSTDEL-----KEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~-------eVr~~AL~aLsnLas~~~~-----~~~Lve-giLe~Lv~LL~  380 (747)
                      ...+.++.+..++. ....       .++..++.++..++.....     ...+.. ++++.|..++.
T Consensus       167 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~l~~~~~~~~L~~~l~  233 (252)
T 5EWP_B          167 LKLGGITQLVNLLE-LPSNYDDSQPLYTQLEAIYHLEDFILNDGDEIPEFLEAVKNSNSIKNLKTLQQ  233 (252)
T ss_dssp             HHTTHHHHHHHTTS-CCTTCCSCSCCHHHHHHHHHHHHHHEETTEECHHHHHHHHTTTHHHHHHHHTT
T ss_pred             HHCChHHHHHHHhc-CCCCCCCCchHHHHHHHHHHHHHHHhcCCCccHHHHHHHHhCChHHHHHHHhh
Confidence            44567777777775 3333       2777788888888764331     223333 66777777663


No 215
>4V3Q_A YIII_M4_AII; DE NOVO PROTEIN, PROTEIN ENGINEERING; HET: GOL, CA; 1.8A {SYNTHETIC CONSTRUCT}
Probab=95.36  E-value=0.00017  Score=64.82  Aligned_cols=134  Identities=25%  Similarity=0.303  Sum_probs=88.0  Template_Neff=12.900

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++..++...+.....+...++++.+...+.+.+..++..++.++..++.........+
T Consensus        51 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  130 (247)
T 4V3Q_A           51 ALPALVQLLSSPNEQILQEALWTLGNIASGGDEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGDEQIQAV  130 (247)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             cHHHHHHHhcCCCHHHHHHHHHHHHHHHcCcHHHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666766677888889999998876544333334445677788888877778888889999988875443333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus       131 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  186 (247)
T 4V3Q_A          131 IDAGALPALVQLLS-SPNEQILQEALWTLGNIASGGDEQIQAVIDAGALPALVQLLS  186 (247)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHCCHHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhc
Confidence            34466777777776 4566778888888888876432 2222222 55666665554


No 216
>3GQ2_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.18A {Bos taurus}
Probab=95.28  E-value=0.00022  Score=78.31  Aligned_cols=135  Identities=13%  Similarity=0.116  Sum_probs=92.0  Template_Neff=10.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ-QVY-QLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~-~li-~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .++.++.++...+..++..++.+|..++...+.... .+. ..+.++.++.++.+.+..++..++.+|..++........
T Consensus       123 ~i~~Ll~ll~~~~~~~~~~al~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~~~~~~i~~~a~~~L~~l~~~~~~~~~  202 (651)
T 3GQ2_A          123 NVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRSNGAIQK  202 (651)
T ss_dssp             HHHTHHHHTTCCCHHHHHHHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHGGGGGCSSHHHHHHHHHHHHHHHTTCHHHHH
T ss_pred             hHHHHHHHccCCCHHHHHHHHHHHHHHHHhccHHHHHHHHhCccHHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCHHHHH
Confidence            455566666666778889999999998865432221 222 345778888888877778889999999999874444434


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGN----AEIQKQLTGLLWNLSSTDELKEE-LIA-DALPVLADRVII  381 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d----~eVr~~AL~aLsnLas~~~~~~~-Lve-giLe~Lv~LL~~  381 (747)
                      .+...+.++.++.++. ...    ..++..++.+|.+++........ +.+ ++++.|+.+|..
T Consensus       203 ~l~~~g~~~~L~~ll~-~~~~~~~~~v~~~al~~L~~L~~~~~~~~~~~~e~~~i~~L~~lL~~  265 (651)
T 3GQ2_A          203 IVAFENAFERLLDIIT-EEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEV  265 (651)
T ss_dssp             HHHHTTHHHHHHHHHH-HTTGGGSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCGGGTGGGGCC
T ss_pred             HHHhCChHHHHHHHHH-HhCCCCccHHHHHHHHHHHHHHhCCHHHHHHHHhcChHHHHHHHHhc
Confidence            4445577888888876 322    25777888899998875433333 334 788888888864


No 217
>3GRL_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.0A {Bos taurus}
Probab=95.28  E-value=0.00022  Score=78.31  Aligned_cols=135  Identities=13%  Similarity=0.116  Sum_probs=92.0  Template_Neff=10.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ-QVY-QLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~-~li-~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .++.++.++...+..++..++.+|..++...+.... .+. ..+.++.++.++.+.+..++..++.+|..++........
T Consensus       123 ~i~~Ll~ll~~~~~~~~~~al~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~~~~~~i~~~a~~~L~~l~~~~~~~~~  202 (651)
T 3GRL_A          123 NVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRSNGAIQK  202 (651)
T ss_dssp             HHHHHHHHTTCCCHHHHHHHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHHGGGGCSSHHHHHHHHHHHHHHHTTCHHHHH
T ss_pred             hHHHHHHHccCCCHHHHHHHHHHHHHHHHhccHHHHHHHHhCccHHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCHHHHH
Confidence            455566666666778889999999998865432221 222 345778888888877778889999999999874444434


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGN----AEIQKQLTGLLWNLSSTDELKEE-LIA-DALPVLADRVII  381 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d----~eVr~~AL~aLsnLas~~~~~~~-Lve-giLe~Lv~LL~~  381 (747)
                      .+...+.++.++.++. ...    ..++..++.+|.+++........ +.+ ++++.|+.+|..
T Consensus       203 ~l~~~g~~~~L~~ll~-~~~~~~~~~v~~~al~~L~~L~~~~~~~~~~~~e~~~i~~L~~lL~~  265 (651)
T 3GRL_A          203 IVAFENAFERLLDIIT-EEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEV  265 (651)
T ss_dssp             HHHHTTHHHHHHHHHH-HHTGGGSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCGGGGGGGGCC
T ss_pred             HHHhCChHHHHHHHHH-HhCCCCccHHHHHHHHHHHHHHhCCHHHHHHHHhcChHHHHHHHHhc
Confidence            4445577888888876 322    25777888899998875433333 334 788888888864


No 218
>5AFF_A SYMPORTIN 1, RIBOSOMAL PROTEIN L5; CHAPERONE, RIBOSOME BIOGENESIS, ALPHA SOLENOID.; 3.398A {CHAETOMIUM THERMOPHILUM}
Probab=95.22  E-value=0.00026  Score=78.85  Aligned_cols=94  Identities=14%  Similarity=0.083  Sum_probs=66.2  Template_Neff=8.800

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLV-DLLRSPNQNVQQAAAGALRNLVFRS-TTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll-~lL~s~d~eVr~~AL~aLs~La~~~-~~~~  322 (747)
                      ..++.|+..+.+.++..+..++.+|.+++.. +.....+...++++.|+ .++.+.+..++..++.+|.+++... ....
T Consensus        12 ~~i~~Li~~L~s~~~~~r~~A~~aL~~L~~d-~~~r~~ll~~g~v~~Li~~lL~d~~~~v~~~a~~aLrnLs~~~~~~~~   90 (654)
T 5AFF_A           12 DKILPVLKDLKSPDAKSRTTAAGAIANIVQD-AKCRKLLLREQVVHIVLTETLTDNNIDSRAAGWEILKVLAQEEEADFC   90 (654)
T ss_dssp             HHHHHHHHHHHSSCTTHHHHHHHHHHHHHCC-HHHHHHHHHTTHHHHHHHTGGGCSSHHHHHHHHHHHHHHHHHSCHHHH
T ss_pred             CchHHHHHHcCCCCHHHHHHHHHHHHHHHcC-HHHHHHHHHCChHHHHHHHHccCCCHHHHHHHHHHHHHHhccCchhHH
Confidence            3456677777777888899999999998754 44444555567888887 7787777889999999999997643 2222


Q NP_000290.2     323 LETRRQNGIREAVSLLR  339 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~  339 (747)
                      ..++..+++..|..++.
T Consensus        91 ~~l~~~~il~~L~~lL~  107 (654)
T 5AFF_A           91 VHLYRLDVLTAIEHAAK  107 (654)
T ss_dssp             HHHHHTTHHHHHHHHHH
T ss_pred             HHHHHCChHHHHHHHHH
Confidence            33444566666666654


No 219
>6QH5_B AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=95.19  E-value=0.00023  Score=72.97  Aligned_cols=107  Identities=12%  Similarity=0.043  Sum_probs=72.0  Template_Neff=12.900

Q NP_000290.2     243 SGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       243 ~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      ...+++.+...+.+.++.++..++.++..+....       ....+++.+...+.+.++.++..++.++..+....+...
T Consensus        84 ~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~-------~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~  156 (592)
T 6QH5_B           84 AIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDK-------ITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMV  156 (592)
T ss_pred             HHHHHHHHHHHccCCCHHHHHHHHHHHHHHcchh-------hHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCchhh
Confidence            4445666666777777888888888888775421       112355666666777778889999999888875433211


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                         ....+++.+...+. +.++.++..++.++..+...
T Consensus       157 ---~~~~~~~~l~~~l~-d~~~~vr~~a~~~l~~~~~~  190 (592)
T 6QH5_B          157 ---EDQGFLDSLRDLIA-DSNPMVVANAVAALSEISES  190 (592)
T ss_pred             ---cCccHHHHHHHHhC-CCCHHHHHHHHHHHHHHHhc
Confidence               11245666666675 55678888899988888764


No 220
>3C2G_A Sys-1 protein, Pop-1 8-residue peptide; beta-catenin, phylogeny, SYS-1, POP-1, Caenorhabditis; HET: MSE; 2.5A {Caenorhabditis elegans}
Probab=95.17  E-value=0.00033  Score=77.69  Aligned_cols=189  Identities=17%  Similarity=0.156  Sum_probs=108.5  Template_Neff=5.600

Q NP_000290.2     260 KYQAIGAYYIQHTCFQDESAKQQVYQL-GG----------ICKLVDLLRSP----------------N----QNVQQAAA  308 (747)
Q Consensus       260 eVr~sAL~aLsnLs~~~~~~~~~li~~-~I----------L~~Ll~lL~s~----------------d----~eVr~~AL  308 (747)
                      .+...++.++..++..+......+... +.          +..|+.++...                +    +.+...+.
T Consensus       185 ~~~~~i~d~Lr~L~~~n~~~K~~~l~~~g~~~~~~~~~~~I~~Ll~IL~~~~~~~~~~~~e~~~~~~~~~~~e~ll~~t~  264 (619)
T 3C2G_A          185 MINPAIFIIFRFIISKDTRLKDYFIWNNNPHDQPPPPTGLIIKLNAVMIGSYRLIAGQNPETLPQNPELAHLIQVIIRTF  264 (619)
T ss_dssp             GCCTHHHHHHHHHHTTCHHHHHHHHHTTCCTTSCCCTTSHHHHHHHHHHHHHHHHTTCCGGGGGGCHHHHHHHHHHHHHH
T ss_pred             chHHHHHHHHHHHhcCCHHHHHHHHhcCCCCCCCCCCchHHHHHHHHHHHhHhhhcCCCcccCCCCccHHHHHHHHHHHH
Confidence            344556667777766544443333332 23          56676666531                1    44555666


Q NP_000290.2     309 GALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCD  388 (747)
Q Consensus       309 ~aLs~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL~~~~~~~~~  388 (747)
                      .+|..+. ........+...+.++.|...+. ..++.+...++++|.++.........-+++.+..++.+|..       
T Consensus       265 ~lLk~Ls-~~sn~a~~~V~~gGvq~L~~~L~-~~S~rlv~~~L~~LrnlSDa~~~~~~~l~~ll~~lv~ll~~-------  335 (619)
T 3C2G_A          265 DLLGLLL-HDSDAIDGFVRSDGVGAITTVVQ-YPNNDLIRAGCKLLLQVSDAKALAKTPLENILPFLLRLIEI-------  335 (619)
T ss_dssp             HHHHHHC-CSHHHHHHHHHTTHHHHHHHHTT-SSCHHHHHHHHHHHHHHTTCGGGGTSCCTTHHHHHHHHHHH-------
T ss_pred             HHHHHHh-CCcchHHHHHHCCHHHHHHHHcc-CCCHHHHHHHHHHHHHHHchHHHcCCchHHHHHHHHHHHhc-------
Confidence            7777666 33333345666788888888886 67788999999999999865432212223566667776621       


Q NP_000290.2     389 GNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAA----  464 (747)
Q Consensus       389 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~----  464 (747)
                              .-|+.+..-+||+|..-.                     ....--+.+---.|-|+.|+.-+..+...    
T Consensus       336 --------~~D~~iv~~~tG~LsNlt---------------------~nn~~NK~~~i~~ggi~~Li~~i~~~~~~~~~~  386 (619)
T 3C2G_A          336 --------HPDDEVIYSGTGFLSNVV---------------------AHKQHVKDIAIRSNAIFLLHTIISKYPRLDELT  386 (619)
T ss_dssp             --------CCCHHHHHHHHHHHHHHS---------------------TTCHHHHHHHHHTTHHHHHHHHHHTSCCGGGCC
T ss_pred             --------CCCHHHHHHHHHHHHHHH---------------------cCChhHHHHHHhCCHHHHHHHHHHhCCccccCC
Confidence                    237888888898875311                     11111111111234445555444333210    


Q NP_000290.2     465 ----SRCDDKSVENCMCVLHNLSYRL  486 (747)
Q Consensus       465 ----~~~~~~~~~~~~~~~~~~~~~~  486 (747)
                          -+-...-.|||.|.|+||..+-
T Consensus       387 ~~~~~~~~eeI~e~~l~aLr~Lt~~h  412 (619)
T 3C2G_A          387 DAPKRNRVCEIICNCLRTLNNFLMMW  412 (619)
T ss_dssp             SHHHHHHHHHHHHHHHHHHHHHHGGG
T ss_pred             CCchhhhhHHHHHHHHHHHHHHhccC
Confidence                0011345899999999998874


No 221
>4FDD_A Transportin-1, RNA-binding protein FUS; HEAT repeats, Karyopherin, nuclear import; 2.3A {Homo sapiens}
Probab=95.09  E-value=0.00028  Score=75.31  Aligned_cols=157  Identities=12%  Similarity=0.083  Sum_probs=93.3  Template_Neff=13.300

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      ..++.+...+. +.++.++..++.++..++...+.     ..... -..+++.+...+.+.+..++..++.++..++.. 
T Consensus       629 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~  701 (852)
T 4FDD_A          629 NILTLMYQCMQ-DKMPEVRQSSFALLGDLTKACFQ-----HVKPC-IADFMPILGTNLNPEFISVCNNATWAIGEISIQM  701 (852)
T ss_dssp             CHHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHCGG-----GTGGG-HHHHHHHHHHTCCTTSHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHh-CCCHHHHHHHHHHHHHHHHHHHH-----hHHHH-HHHHHHHHHhhCCcccHHHHHHHHHHHHHHHHHc
Confidence            35566666666 35677888899999988764321     11111 134666677777777788888999999888765 


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      ..........+++.+...+...    ..+..++..++.+|..+....+....... ..++..++..+....+..++..++
T Consensus       702 ~~~~~~~~~~i~~~l~~~l~~~----~~~~~~~~~~~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~~~~~~~~~a~  776 (852)
T 4FDD_A          702 GIEMQPYIPMVLHQLVEIINRP----NTPKTLLENTAITIGRLGYVCPQEVAPML-QQFIRPWCTSLRNIRDNEEKDSAF  776 (852)
T ss_dssp             GGGGGGGTHHHHHHHHHHHTCS----SCCHHHHHHHHHHHHHHHHHCHHHHGGGH-HHHHHHHHHHHHTSCSSHHHHHHH
T ss_pred             CccchhhHHHHHHHHHHHHcCC----CCChhHHHHHHHHHHHHHHHCHHHhHHHH-HHhHHHHHHHhhcCCCHHHHHHHH
Confidence            2111111123556666666541    01467788888999888765332111111 124445555554322567788888


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .+|..++...
T Consensus       777 ~~l~~l~~~~  786 (852)
T 4FDD_A          777 RGICTMISVN  786 (852)
T ss_dssp             HHHHHHHHHC
T ss_pred             HHHHHHHhhC
Confidence            8887776543


No 222
>4P6Z_B BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=95.03  E-value=0.00031  Score=72.53  Aligned_cols=106  Identities=11%  Similarity=0.035  Sum_probs=69.9  Template_Neff=12.700

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.++.++..++.++..+....       ....+++.+...+.+.++.++..++.++..+....+... 
T Consensus       101 ~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~-------~~~~~~~~l~~~l~~~~~~vr~~a~~~L~~l~~~~~~~~-  172 (600)
T 4P6Z_B          101 IMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDK-------ITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLV-  172 (600)
T ss_pred             HHHHHHHHHHccCCCHHHHHHHHHHHhcCCchH-------HHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHhhChHHh-
Confidence            344555566666667788888888887775321       112455666666777778888889998888875433211 


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                        ....+++.+...+. +.++.++..++.++..+...
T Consensus       173 --~~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~  206 (600)
T 4P6Z_B          173 --EDQGFLDTLKDLIS-DSNPMVVANAVAALSEIAES  206 (600)
T ss_pred             --hccChHHHHHHHhc-CCCHHHHHHHHHHHHHHHhh
Confidence              11345666777775 55678888888888888764


No 223
>2JKT_A AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ALTERNATIVE SPLICING, PHOSPHOPROTEIN, PHOSPHORYLATION, PROTEIN; HET: SEP, SO4; 3.4A {MUS MUSCULUS}
Probab=95.01  E-value=0.00032  Score=73.46  Aligned_cols=144  Identities=13%  Similarity=0.048  Sum_probs=89.0  Template_Neff=12.300

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSD--VVRSGASLLSNMSR  624 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~e--Vr~~AL~aLsnLa~  624 (747)
                      ..++.|+.++. +.+..++..++.++..+......          ....+++.|...+.+.+..  ++..++++|+.+..
T Consensus       441 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~----------~~~~~~~~l~~~l~~~~~~~~v~~~a~~~l~~~~~  509 (623)
T 2JKT_A          441 WYVDTILNLIR-IAGDYVSEEVWYRVIQIVINRDD----------VQGYAAKTVFEALQAPACHENLVKVGGYILGEFGN  509 (623)
T ss_dssp             HHHHHHHHHTT-TTGGGCCHHHHHHHHHHHHHCST----------THHHHHHHHHHHTTSSSCCHHHHHHHHHHHHHSST
T ss_pred             HHHHHHHHHHH-HHcccCCHHHHHHHHHHHhcChh----------HHHHHHHHHHHHHhCccCCHHHHHHHHHHHHHHHH
Confidence            35666777776 35566777788888777653211          1234566666666655544  78888888888775


Q NP_000290.2     625 HPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLC---RSSASPKA  700 (747)
Q Consensus       625 ~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL---~s~~d~eV  700 (747)
                      .... .......+++.|...+.+      .+..++..++.+|..++...+.     . ...+..++..+   .+. ++.+
T Consensus       510 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~a~~al~~l~~~~~~-----~-~~~l~~ll~~l~~~~~~-~~~v  576 (623)
T 2JKT_A          510 LIAGDPRSSPLIQFNLLHSKFHL------CSVPTRALLLSTYIKFVNLFPE-----V-KATIQDVLRSDSQLKNA-DVEL  576 (623)
T ss_dssp             TSSSSGGGCHHHHHHHHHHHHTT------SCHHHHHHHHHHHHHHHHHCTT-----T-HHHHHTTSSSHHHHTCS-SHHH
T ss_pred             HhcCCCCCChHHHHHHHHHhcCC------CCHHHHHHHHHHHHHHHHhCHH-----H-HHHHHHHHHhccccCCC-CHHH
Confidence            4111 111111355566666655      3577889999999998864332     1 13455555555   444 7788


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..+...
T Consensus       577 r~~a~~~l~~~~~~  590 (623)
T 2JKT_A          577 QQRAVEYLRLSTVA  590 (623)
T ss_dssp             HHHHHHHHHHHHSS
T ss_pred             HHHHHHHHHHhccC
Confidence            99999998877654


No 224
>5IZ8_A Adenomatous polyposis coli protein, ACE-ALA-GLY-GLU-ALA-LEU-ALA-ASP-NH2; APC, ASEF, Colon CANCER, Drug; HET: PGE; 3.06A {Homo sapiens}
Probab=94.95  E-value=0.00036  Score=67.82  Aligned_cols=162  Identities=22%  Similarity=0.254  Sum_probs=121.7  Template_Neff=12.000

Q NP_000290.2     543 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLK-EKGLPQIARLLQSGN----SDVVRSGAS  617 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie-~giI~~Ll~LL~s~d----~eVr~~AL~  617 (747)
                      +.+.++++.|+.++....++.++..++++|.+++...+.     ....+.+ .++++.|+.++...+    ..++..++.
T Consensus       166 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~  240 (354)
T 5IZ8_A          166 LREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTE-----NKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGG  240 (354)
T ss_dssp             HHHTTHHHHHHHHHHHCCSHHHHHHHHHHHHHHHTSCHH-----HHHHHHTSTTHHHHHHHHTTCCCTTSCCHHHHHHHH
T ss_pred             HHHCCHHHHHHHHHHhcCCHHHHHHHHHHHHHHHcCChH-----hHHHHHhhccHHHHHHHHHhhcCCCCcHHHHHHHHH
Confidence            356778888888887225677888999999999875232     2334455 688899998887533    678888999


Q NP_000290.2     618 LLSNMSR----HPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLC  692 (747)
Q Consensus       618 aLsnLa~----~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL  692 (747)
                      +|.+++.    .... ..+...++++.++.++..      .++.++..++.+|.+++...+.....+.+.++++.|+.++
T Consensus       241 ~L~~l~~~~~~~~~~~~~l~~~~~~~~l~~~l~~------~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l  314 (354)
T 5IZ8_A          241 ILRNVSSLIATNEDHRQILRENNCLQTLLQHLKS------HSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLI  314 (354)
T ss_dssp             HHHHHHHHHHTCHHHHHHHHTTTHHHHHHHTTTC------SCHHHHHHHHHHHHHHSSSCHHHHHHHHTTTHHHHHHHHS
T ss_pred             HHHHHHHHhcCCHHHHHHHHHCCHHHHHHHHhhc------CCHHHHHHHHHHHHHHHccCHHHHHHHHhCCHHHHHHHHH
Confidence            9999873    2222 233455678888888876      3677899999999999985466666677778889999988


Q NP_000290.2     693 RSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       693 ~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      .+. ++.++..++.+|.+++...+
T Consensus       315 ~~~-~~~v~~~a~~~L~~l~~~~~  337 (354)
T 5IZ8_A          315 HSK-HKMIAMGSAAALRNLMANRP  337 (354)
T ss_dssp             SCS-SHHHHHHHHHHHHHHHTTCC
T ss_pred             hcc-CHHHHHHHHHHHHHHHccCc
Confidence            866 78899999999999997764


No 225
>5IZA_A Adenomatous polyposis coli protein, ACE-GLY-GLY-GLU-ALA-LEU-ALA-TRP-NH2; APC, ASEF, Colon CANCER, Drug; 1.5A {Homo sapiens}
Probab=94.95  E-value=0.00036  Score=67.81  Aligned_cols=162  Identities=22%  Similarity=0.254  Sum_probs=121.8  Template_Neff=12.000

Q NP_000290.2     543 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLK-EKGLPQIARLLQSGN----SDVVRSGAS  617 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie-~giI~~Ll~LL~s~d----~eVr~~AL~  617 (747)
                      +.+.++++.|+.++....++.++..++++|.+++...+.     ....+.+ .++++.|+.++...+    ..++..++.
T Consensus       166 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~  240 (354)
T 5IZA_A          166 LREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTE-----NKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGG  240 (354)
T ss_dssp             HHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHHTTCHH-----HHHHHHTSTTHHHHHHHHTCSSCSSCCHHHHHHHHH
T ss_pred             HHHCCHHHHHHHHHHhcCCHHHHHHHHHHHHHHHcCChH-----hHHHHHhhccHHHHHHHHHhhcCCCCcHHHHHHHHH
Confidence            356778888888887225677888999999999875232     2334455 688899998887533    678888999


Q NP_000290.2     618 LLSNMSR----HPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLC  692 (747)
Q Consensus       618 aLsnLa~----~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL  692 (747)
                      +|.+++.    .... ..+...++++.++.++..      .++.++..++.+|.+++...+.....+.+.++++.|+.++
T Consensus       241 ~L~~l~~~~~~~~~~~~~l~~~~~~~~l~~~l~~------~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l  314 (354)
T 5IZA_A          241 ILRNVSSLIATNEDHRQILRENNCLQTLLQHLKS------HSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLI  314 (354)
T ss_dssp             HHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHTSSCHHHHHHHHHTTHHHHHHTTT
T ss_pred             HHHHHHHHhcCCHHHHHHHHHCCHHHHHHHHhhc------CCHHHHHHHHHHHHHHHccCHHHHHHHHhCCHHHHHHHHH
Confidence            9999873    2222 233455678888888876      3677899999999999985466666677778889999988


Q NP_000290.2     693 RSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       693 ~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      .+. ++.++..++.+|.+++...+
T Consensus       315 ~~~-~~~v~~~a~~~L~~l~~~~~  337 (354)
T 5IZA_A          315 HSK-HKMIAMGSAAALRNLMANRP  337 (354)
T ss_dssp             TCS-SHHHHHHHHHHHHHHHHTCC
T ss_pred             hcc-CHHHHHHHHHHHHHHHccCc
Confidence            866 78899999999999997764


No 226
>5YVI_A Transportin-1, RNA-binding protein FUS; Importin family, PROTEIN TRANSPORT, PROTEIN; 2.9A {Homo sapiens}
Probab=94.92  E-value=0.00036  Score=74.50  Aligned_cols=156  Identities=12%  Similarity=0.081  Sum_probs=94.0  Template_Neff=13.300

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.+...+. +.++.++..++.++..++.....     .... .-..+++.+...+.+.+..++..++.++..++...
T Consensus       645 ~~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~l~~l~~~l~~~~~~v~~~a~~~l~~l~~~~  717 (868)
T 5YVI_A          645 NILTLMYQCMQ-DKMPEVRQSSFALLGDLTKACFQ-----HVKP-CIADFMPILGTNLNPEFISVCNNATWAIGEISIQM  717 (868)
T ss_dssp             CHHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHCHH-----HHGG-GHHHHHHHHHHTCCTTSHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHh-CCCHHHHHHHHHHHHHHHHHhHH-----hHHH-HHHHHHHHHHhcCCcccHHHHHHHHHHHHHHHHHc
Confidence            34555666665 35677888899999888764321     0111 11346666777777777888999999999888652


Q NP_000290.2     627 -LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 -e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                       .........+++.+...+.+.    ..+..++..++.+|..++...+....... ..+++.++..+.+..++.++..++
T Consensus       718 ~~~~~~~~~~i~~~l~~~l~~~----~~~~~~~~~~~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~~~~~~r~~~~  792 (868)
T 5YVI_A          718 GIEMQPYIPMVLHQLVEIINRP----NTPKTLLENTAITIGRLGYVCPQEVAPML-QQFIRPWCTSLRNIRDNEEKDSAF  792 (868)
T ss_dssp             GGGGGGGGGGTHHHHHHHHTCT----TCCHHHHHHHHHHHHHHHHHCHHHHGGGH-HHHHHHHHHHHTTSCSSHHHHHHH
T ss_pred             cccchhcHHHHHHHHHHHhcCC----CCChhHHHHHHHHHHHHHHHCHHHHHHHH-HHHHHHHHHHhhcCCChHHHHHHH
Confidence             111111123566666666541    01467888899999988865332111111 234555555555322567888888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .++..+...
T Consensus       793 ~~l~~l~~~  801 (868)
T 5YVI_A          793 RGICTMISV  801 (868)
T ss_dssp             HHHHHC-CC
T ss_pred             HHHHHHHhh
Confidence            888888754


No 227
>6QH7_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: SEP; 3.4A {Rattus norvegicus}
Probab=94.91  E-value=0.00038  Score=73.02  Aligned_cols=108  Identities=17%  Similarity=0.103  Sum_probs=69.7  Template_Neff=12.200

Q NP_000290.2     242 CSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLL--RSPNQNVQQAAAGALRNLVFRST  319 (747)
Q Consensus       242 ~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL--~s~d~eVr~~AL~aLs~La~~~~  319 (747)
                      ....+++.+...+.+.++.++..++.++..+....       ....+++.+...+  .+.++.++..++.++..+.....
T Consensus       108 ~~~~~~~~l~~~l~~~~~~vr~~al~~l~~~~~~~-------~~~~l~~~l~~~l~~~~~~~~vr~~a~~~L~~~~~~~~  180 (621)
T 6QH7_A          108 LIRLINNAIKNDLASRNPTFMGLALHCIANVGSRE-------MAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSP  180 (621)
T ss_dssp             HHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHCCHH-------HHHHHTTHHHHHHTTSCCCHHHHHHHHHHHHHHHHHCG
T ss_pred             HHHHHHHHHHHHHhcCCHHHHHHHHHHHHhhCCHH-------HHHHHHhhHHHHHHcCCCCHHHHHHHHHHHHHHHHHCh
Confidence            33445556666666677788888888888775421       1123455566666  66677888888888888765332


Q NP_000290.2     320 TNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       320 ~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...   .....++.+...+. +.++.++..++.++..+...
T Consensus       181 ~~~---~~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~  217 (621)
T 6QH7_A          181 DLV---PMGDWTSRVVHLLN-DQHLGVVTAATSLITTLAQK  217 (621)
T ss_dssp             GGC---CCCTTHHHHHHGGG-CSSHHHHHHHHHHHHHHHTT
T ss_pred             hhc---CccchHHHHHHHhc-CCCHHHHHHHHHHHHHHHHh
Confidence            211   11245566667775 55677888888888887753


No 228
>1B3U_A PROTEIN PHOSPHATASE PP2A, 65 KD; SCAFFOLD PROTEIN, PP2A, PHOSPHORYLATION, HEAT; 2.3A {Homo sapiens} SCOP: a.118.1.2
Probab=94.85  E-value=0.0004  Score=70.07  Aligned_cols=146  Identities=11%  Similarity=0.055  Sum_probs=95.0  Template_Neff=13.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.+..++. +.+..++..++.+|..+......      . . ....+++.+...+.+.+..++..++.++..+....
T Consensus       441 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~------~-~-~~~~~~~~l~~~l~~~~~~~r~~~~~~l~~l~~~~  511 (588)
T 1B3U_A          441 KLNSLCMAWLV-DHVYAIREAATSNLKKLVEKFGK------E-W-AHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVC  511 (588)
T ss_dssp             HHHHHHHHGGG-CSSHHHHHHHHHHHHHHHHHHCH------H-H-CCCCCHHHHHHTTTCSCHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHhc-CChHHHHHHHHHHHHHHHHHhCh------H-H-HHHhHHHHHHHhhcCCCHHHHHHHHHHHHHHHHHh
Confidence            34566667776 46677888888888888764221      1 1 12356677777777777888888888888887642


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      .. ......+++.+...+.+      .++.++..++.++..+......   ......+++.+...+.+. ++.++..+..
T Consensus       512 ~~-~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~---~~~~~~~~~~l~~~l~~~-~~~vr~~a~~  580 (588)
T 1B3U_A          512 GQ-DITTKHMLPTVLRMAGD------PVANVRFNVAKSLQKIGPILDN---STLQSEVKPILEKLTQDQ-DVDVKYFAQE  580 (588)
T ss_dssp             HH-HHCCCCCHHHHHHGGGC------SCHHHHHHHHHHHHHHGGGSCH---HHCCCCCHHHHHHHTTCS-SHHHHHHHHH
T ss_pred             CH-HHHHhchHHHHHHHhCC------CcHHHHHHHHHHHHHHHHHhcC---CcchHHHHHHHHHHhcCC-ChhHHHHHHH
Confidence            11 11123455666666665      3678899999999988754211   112224566677777765 7788888888


Q NP_000290.2     707 LLSDMW  712 (747)
Q Consensus       707 aLsnL~  712 (747)
                      ++..+.
T Consensus       581 ~l~~l~  586 (588)
T 1B3U_A          581 ALTVLS  586 (588)
T ss_dssp             HHHHTT
T ss_pred             HHHHhh
Confidence            887765


No 229
>4HM9_A Beta-catenin-like protein 1; all alpha-helical, armadillo repeats, PROTEIN; 3.1001A {Homo sapiens}
Probab=94.77  E-value=0.00057  Score=75.04  Aligned_cols=161  Identities=14%  Similarity=0.093  Sum_probs=111.6  Template_Neff=8.100

Q NP_000290.2     543 LYHSDAIRTYLNLMGKSK--KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-----SG----NSDV  611 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~--d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-----s~----d~eV  611 (747)
                      +.+.++++.|+.+|.. .  ....+..|+.+|.+|+...+.     ....+.+.++++.|+.+|.     ++    ....
T Consensus       241 i~~~g~l~~Ll~lL~~-~~~~~~~k~~AaeiL~~L~~~~~~-----~r~~l~~~g~I~~LL~lL~~y~~~d~~~~~e~e~  314 (568)
T 4HM9_A          241 GAQQGLLQWLLKRLKA-KMPFDANKLYCSEVLAILLQDNDE-----NRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEM  314 (568)
T ss_dssp             HCCCCCHHHHHHHHHS-SCCCCHHHHHHHHHHHHHHTTCHH-----HHHHHHHTTHHHHHHHHHGGGTTSCCSSSHHHHH
T ss_pred             HHHCCHHHHHHHHHHc-CCCCHHHHHHHHHHHHHHHcCCHH-----HHHHHHhCchHHHHHHHHHhhhccCCCCHHHHHH
Confidence            3567889999999983 3  466778899999999875332     2444456889999999995     11    1234


Q NP_000290.2     612 VRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS--QPQLAKQYFSSSMLNNI  688 (747)
Q Consensus       612 r~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~--s~e~~~~Lve~giL~~L  688 (747)
                      ...++.+|.+++..+.. ..++..++++.++.+|..       ....+..|+.+|..++..  .......+++.+++..|
T Consensus       315 ~en~~~aL~~L~~~~~~r~~f~~~~gv~lLv~lL~~-------~~~~~~~Al~vL~~a~~~~~~~~~~~~~ve~ggl~~L  387 (568)
T 4HM9_A          315 MENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLRE-------KKISRSSALKVLDHAMIGPEGTDNCHKFVDILGLRTI  387 (568)
T ss_dssp             HHHHHHHHHHHTTSTHHHHHHHHTTHHHHHHHHHHH-------TSTTHHHHHHHHHHHHCSGGGHHHHHHHHHTTCHHHH
T ss_pred             HHHHHHHHHHHhCCHHHHHHHHHCChHHHHHHHHhC-------ChhHHHHHHHHHHHHhcCCCChhHHHHHHHHchHHHH
Confidence            55668888888876544 355666788888888875       234567778888665442  34456677777888888


Q NP_000290.2     689 INLCRSS---------ASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       689 l~LL~s~---------~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      +.++...         ......+.++.+|..|+....
T Consensus       388 ~~ll~~~~~~~~~~~~~~~e~~E~~~~iL~sL~~~~~  424 (568)
T 4HM9_A          388 FPLFMKSPRKIKKVGTTEKEHEEHVCSILASLLRNLR  424 (568)
T ss_dssp             HHHHHSCCCCCSSSSCCHHHHHHHHHHHHHHHHHHCC
T ss_pred             HHHHhcCcchhcCCCCCHHHHHHHHHHHHHHHHhcCC
Confidence            8876532         134567888888888886543


No 230
>6QH5_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=94.76  E-value=0.00048  Score=72.19  Aligned_cols=144  Identities=13%  Similarity=0.054  Sum_probs=85.0  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSD--VVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~e--Vr~~AL~aLsnLa~~  625 (747)
                      .++.|+..+. +.++.++..++.++..+......          ....+++.+...+.+.+..  ++..++++++.+...
T Consensus       442 ~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~----------~~~~~~~~l~~~l~~~~~~~~vr~~a~~~l~~~~~~  510 (621)
T 6QH5_A          442 YVDTILNLIR-IAGDYVSEEVWYRVIQIVINRDD----------VQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNL  510 (621)
T ss_pred             HHHHHHHHhc-CCCHHHcHHHHHHHHHHHhcCHH----------HHHHHHHHHHHHhhCCCCCHHHHHHHHHHHHHHHhh
Confidence            4556666665 34556666777777766543111          1233455666666655544  777788888777654


Q NP_000290.2     626 P-LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLC---RSSASPKAA  701 (747)
Q Consensus       626 ~-e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL---~s~~d~eVr  701 (747)
                      . .........+++.|...+.+      .+..++..++.+|..+....+.     . ...+..++..+   .+. ++.++
T Consensus       511 ~~~~~~~~~~~~~~~L~~~l~~------~~~~vr~~a~~al~~l~~~~~~-----~-~~~l~~ll~~l~~~~~~-~~~vr  577 (621)
T 6QH5_A          511 IAGDPRSSPLIQFNLLHSKFHL------CSVPTRALLLSTYIKFVNLFPE-----V-KATIQDVLRSDSQLKNA-DVELQ  577 (621)
T ss_pred             CCCCCCCCHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhCHH-----H-HhHHHHHHHHHHhcCCC-CHHHH
Confidence            1 11110111245556666655      3567888899999988764322     1 12344555544   444 77889


Q NP_000290.2     702 EAARLLLSDMWSSK  715 (747)
Q Consensus       702 ~aAL~aLsnL~~~~  715 (747)
                      ..++.++..+....
T Consensus       578 ~~a~~~l~~~~~~~  591 (621)
T 6QH5_A          578 QRAVEYLRLSTVAS  591 (621)
T ss_pred             HHHHHHHHHhCCCc
Confidence            99999988876543


No 231
>5MFO_F YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: CA, EDO; 1.3A {synthetic construct}
Probab=94.68  E-value=0.00052  Score=58.87  Aligned_cols=134  Identities=25%  Similarity=0.276  Sum_probs=89.8  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++.........+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus        47 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  126 (202)
T 5MFO_F           47 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV  126 (202)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45566666777777888899999999886544333334444577777777777777888889999998876543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..+..++..++.++..++..... ...+.. ++++.|..++.
T Consensus       127 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  182 (202)
T 5MFO_F          127 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQKQAVKEAGAEPALEQLQS  182 (202)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHTTTT
T ss_pred             HHCCHHHHHHHHhc-CCCHHHHHHHHHHHHHHhcChHHHHHHHHHCCHHHHHHHHHc
Confidence            34456777777776 55677888888999888875322 222222 56666666664


No 232
>5MFO_E YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: EDO, CA; 1.3A {synthetic construct}
Probab=94.66  E-value=0.00054  Score=58.80  Aligned_cols=134  Identities=25%  Similarity=0.276  Sum_probs=89.7  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++.........+...++++.+...+.+.+..++..++.++..++.........+
T Consensus        47 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  126 (202)
T 5MFO_E           47 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV  126 (202)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45566666777778888899999999886544333334444577777777777777888889999988876543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..+..++..++.++..++..... ...+.. ++++.|..++.
T Consensus       127 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  182 (202)
T 5MFO_E          127 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQKQAVKEAGAEPALEQLQS  182 (202)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHCCHHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCHHHHHHHHHHCCHHHHHHHHHc
Confidence            33456777777776 55677888889999888875322 222222 56666666654


No 233
>4MFU_A Beta-catenin-like protein 1; ARM repeats, GENE REGULATION; 2.744A {Homo sapiens}
Probab=94.63  E-value=0.00067  Score=72.78  Aligned_cols=161  Identities=14%  Similarity=0.093  Sum_probs=111.4  Template_Neff=8.700

Q NP_000290.2     543 LYHSDAIRTYLNLMGKSK--KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-----SG----NSDV  611 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~--d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-----s~----d~eV  611 (747)
                      +.+.++++.|+.++.. .  ....+..++.+|.+++...+.     ....+.+.++++.|+.++.     ++    ....
T Consensus       163 i~~~~~l~~Ll~~L~~-~~~~~~~k~~a~~~L~~L~~~~~~-----~~~~l~~~g~i~~Ll~lL~~~~~~d~~~~~~~e~  236 (490)
T 4MFU_A          163 GAQQGLLQWLLKRLKA-KMPFDANKLYCSEVLAILLQDNDE-----NRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEM  236 (490)
T ss_dssp             HCCCCCHHHHHHHHHC-CSCCCHHHHHHHHHHHHHHTTCHH-----HHHHHHHTTHHHHHHHHHHTTSSSCCSSHHHHHH
T ss_pred             HHHCCHHHHHHHHHHc-CCCCHHHHHHHHHHHHHHHcCCHH-----HHHHHHhCchHHHHHHHHHhhhhcCCCCHHHHHH
Confidence            3567889999999983 3  467788899999999875332     2444456789999999985     11    1234


Q NP_000290.2     612 VRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS--QPQLAKQYFSSSMLNNI  688 (747)
Q Consensus       612 r~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~--s~e~~~~Lve~giL~~L  688 (747)
                      ...++.+|++++..+.. ..++..++++.++.++..       ....+..|+.+|...+..  ++.....+++.+++..|
T Consensus       237 ~en~~~aL~~L~~~~~~~~~f~~~~gi~llv~lL~~-------~~~~~~~AL~~L~~a~~~~~~~~~~~~~v~~ggl~~L  309 (490)
T 4MFU_A          237 MENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLRE-------KKISRSSALKVLDHAMIGPEGTDNCHKFVDILGLRTI  309 (490)
T ss_dssp             HHHHHHHHHHHHHSTHHHHHHHHTTHHHHHHHHHHT-------TSSTHHHHHHHHHHHHSSGGGHHHHHHHHHTTHHHHH
T ss_pred             HHHHHHHHHHHhCCHHHHHHHHHCCcHHHHHHHHhC-------ChhHHHHHHHHHHHHhcCCCCHHHHHHHHHHchHHHH
Confidence            45568888888876444 355666788888888865       234566677777665442  34456677777888888


Q NP_000290.2     689 INLCRSS---------ASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       689 l~LL~s~---------~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      +.++...         .+..+.+.++.+|..|+....
T Consensus       310 ~~~l~~~~~~~~~~~~~~~~~~E~~~~il~sL~~~~~  346 (490)
T 4MFU_A          310 FPLFMKSPRKIKKVGTTEKEHEEHVCSILASLLRNLR  346 (490)
T ss_dssp             HHHHHCCCCSCCSSCCCSHHHHHHHHHHHHHHHHHCC
T ss_pred             HHHHhcCcccccCCCCCHHHHHHHHHHHHHHHHhcCC
Confidence            8877542         134677888899888887543


No 234
>2NYL_A Protein phosphatase 2, regulatory subunit; HEAT repeat, HYDROLASE-HYDROLASE INHIBITOR COMPLEX; HET: DAL, MSE, ACB, 1ZN, DAM, FGA; 3.8A {Homo sapiens} SCOP: a.118.1.2
Probab=94.58  E-value=0.00059  Score=68.47  Aligned_cols=145  Identities=11%  Similarity=0.056  Sum_probs=94.9  Template_Neff=13.500

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+..++. +.++.++..++.+|..+......      . . ....+++.+...+.+.+..++..++.++..+.....
T Consensus       436 ~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~------~-~-~~~~~~~~l~~~l~~~~~~~r~~~~~~l~~l~~~~~  506 (582)
T 2NYL_A          436 LNSLCMAWLV-DHVYAIREAATSNLKKLVEKFGK------E-W-AHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCG  506 (582)
T ss_dssp             CHHHHHHGGG-CSSHHHHHHHHHHHHHHHHHHHH------H-H-HHHHTHHHHHHTTTCSSHHHHHHHHHHHHHHGGGSC
T ss_pred             HHHHHHHHhc-CCHHHHHHHHHHHHHHHHHHHCh------h-h-HHhcHHHHHHHhcCCCcHHHHHHHHHHHHHHHHHhC
Confidence            4555666776 46777888899998888764221      1 1 124566777777777778888888998888876421


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .. .....+++.+...+.+      .++.++..++.++..+......   ......+++.+...+.+. ++.++..++.+
T Consensus       507 ~~-~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~---~~~~~~~~~~l~~~l~~~-~~~vr~~a~~~  575 (582)
T 2NYL_A          507 QD-ITTKHMLPTVLRMAGD------PVANVRFNVAKSLQKIGPILDN---STLQSEVKPILEKLTQDQ-DVDVKYFAQEA  575 (582)
T ss_dssp             HH-HHHHHTHHHHHHTSSC------SSHHHHHHHHHHHTTSSTTSCH---HHCCCCCHHHTTTTTTCS-SHHHHHHHHTT
T ss_pred             HH-HHHhcHHHHHHHHhcC------ChHHHHHHHHHHHHHHHHHcCC---CCcHHHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence            11 1123355666666665      3678889999999988764211   112224566677777665 77888888888


Q NP_000290.2     708 LSDMW  712 (747)
Q Consensus       708 LsnL~  712 (747)
                      +..++
T Consensus       576 l~~l~  580 (582)
T 2NYL_A          576 LTVLS  580 (582)
T ss_dssp             TTTTT
T ss_pred             HHHhc
Confidence            88765


No 235
>4U2X_F eVP24, KPNA5C; eVP24, importin alpha6, immune antagonist; 3.153A {Zaire ebolavirus}
Probab=94.35  E-value=0.00082  Score=57.14  Aligned_cols=73  Identities=21%  Similarity=0.253  Sum_probs=49.2  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQ-DESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS  318 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~-~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~  318 (747)
                      +++.+...+.+.++.++..++.++.+++.. .+.....+...++++.+...+...++.++..++.++.+++...
T Consensus        51 ~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~  124 (175)
T 4U2X_F           51 IFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLG  124 (175)
T ss_dssp             CHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHTCHHHHHHGGGCSCHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHhCCHHHHHHHHHHHHHHhcCCCHHHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHHhcc
Confidence            455555666666677888888999888753 2223333334466777777777666777888888888887643


No 236
>3SL9_B Catenin beta-1, B-cell CLL/lymphoma 9; Armadillo repeat, components of the; HET: GOL, EDO, PEG, IMD; 2.2A {Homo sapiens}
Probab=94.35  E-value=0.00082  Score=56.48  Aligned_cols=110  Identities=24%  Similarity=0.309  Sum_probs=73.4  Template_Neff=12.600

Q NP_000290.2     246 TIPKAVQYLSS-QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~s-sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.. .+..++..++.++.+++.. +.....+...++++.+..++...++.++..++.++.+++.........
T Consensus        56 ~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~-~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  134 (167)
T 3SL9_B           56 MVSAIVRTMQNTNDVETARCTAGTLHNLSHH-REGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMA  134 (167)
T ss_pred             hHHHHHHHHhcCCCHHHHHHHHHHHHHHcCC-HhHHHHHHHCCcHHHHHHHhCCCCHHHHHHHHHHHHHHHcCCHhHHHH
Confidence            55566666665 5677888889999888743 333334444567788888887777788888999999888654332222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNL  357 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnL  357 (747)
                      ....++++.+..++. ..++.++..++.++..+
T Consensus       135 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l  166 (167)
T 3SL9_B          135 VRLAGGLQKMVALLN-KTNVKFLAITTDCLQIL  166 (167)
T ss_pred             HHHcCHHHHHHHHhc-CCCHHHHHHHHHHHHHh
Confidence            222456777777776 45566777777776654


No 237
>4I5L_D PP2A A alpha subunit (9-589); EF Hand, Phosphatase, CDC6 (Substrate); HET: FGA, ACB, DAL, MLI, PEG, 1ZN, MAA; 2.43A {Microcystis aeruginosa}
Probab=94.34  E-value=0.0008  Score=67.65  Aligned_cols=110  Identities=11%  Similarity=0.101  Sum_probs=57.6  Template_Neff=13.400

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL-E  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~-~  324 (747)
                      +++.+...+.+.++.++..++.++..+......   ......+++.+...+.+.++.++..++.++..+......... .
T Consensus       239 ~~~~l~~~l~~~~~~vr~~~~~~l~~l~~~~~~---~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~  315 (584)
T 4I5L_D          239 VMPTLRQAAEDKSWRVRYMVADKFTELQKAVGP---EITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCREN  315 (584)
T ss_dssp             THHHHHHHHTCSSHHHHHHHHHTHHHHHHHHHH---HHCCCCCHHHHHHHHTCSSHHHHHHHHTTHHHHHHTSCTTTHHH
T ss_pred             HHHHHHHHhhCCCHHHHHHHHHHHHHHHHHHCC---CCChhhHHHHHHHHhcCCcHHHHHHHHHHHHHHHHhcCccchhh
Confidence            334444455555666777777777666543221   111123455566666666667777777777776643221110 0


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      .....+++.+...+. +.++.++..++.++..+..
T Consensus       316 ~~~~~~~~~l~~~l~-~~~~~vr~~~~~~l~~l~~  349 (584)
T 4I5L_D          316 VIMSQILPCIKELVS-DANQHVKSALASVIMGLSP  349 (584)
T ss_dssp             HCCCCCHHHHHHHHT-CSCHHHHHHHHTTGGGGHH
T ss_pred             HHHHhHHHHHHHHcc-CCCHHHHHHHHHHHHHHHH
Confidence            111234455555554 3445566666666665544


No 238
>4U2X_E eVP24, KPNA5C; eVP24, importin alpha6, immune antagonist; 3.153A {Zaire ebolavirus}
Probab=94.27  E-value=0.00091  Score=56.83  Aligned_cols=73  Identities=21%  Similarity=0.253  Sum_probs=49.3  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQ-DESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS  318 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~-~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~  318 (747)
                      +++.+...+.+.++.++..++.++.+++.. .......+...+.++.+...+.+.++.++..++.++.+++...
T Consensus        51 ~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~  124 (175)
T 4U2X_E           51 IFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLG  124 (175)
T ss_dssp             CHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHTCHHHHHHGGGCSCHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHhcCHHHHHHHHHHHHHHcCCCCHHHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHHhhc
Confidence            445555666666677888889999988753 2222333334456777777777667778888888888887654


No 239
>4UQI_B AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ENDOCYTOSIS, PROTEIN TRANSPORT, LIPID BINDING; HET: IHP; 2.79A {RATTUS NORVEGICUS}
Probab=94.24  E-value=0.00095  Score=70.34  Aligned_cols=106  Identities=12%  Similarity=0.039  Sum_probs=70.7  Template_Neff=12.200

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.++.++..++.++..+....       ....+++.+...+.+.++.++..++.++..+........ 
T Consensus        85 ~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~-------~~~~l~~~l~~~l~~~~~~vr~~a~~~L~~l~~~~~~~~-  156 (657)
T 4UQI_B           85 IMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDK-------ITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMV-  156 (657)
T ss_pred             HHHHHHHHHHhcCCCHHHHHHHHHHHhhcCCch-------hHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCHHHh-
Confidence            445555666666677788888888888775421       112355666666777778888889988888875433221 


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                        ....+++.+...+. +.++.++..++.++..+...
T Consensus       157 --~~~~~~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~  190 (657)
T 4UQI_B          157 --EDQGFLDSLRDLIA-DSNPMVVANAVAALSEISES  190 (657)
T ss_pred             --cCcchHHHHHHHhc-CCCHHHHHHHHHHHHHHHhc
Confidence              12245666777776 55678888899988888764


No 240
>5KC2_B Phosphatidylinositol 3-kinase VPS34 (E.C.2.7.1.137), Serine/threonine-protein; autophagy, phosphatidylinositol 3-kinase (PtdIns3K), endocytosis; 28.0A {Saccharomyces cerevisiae}
Probab=94.04  E-value=0.0013  Score=79.08  Aligned_cols=155  Identities=11%  Similarity=0.032  Sum_probs=110.7  Template_Neff=9.500

Q NP_000290.2     544 YHSDAIRTYLNLM---GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIG----------------------LKEKGLP  598 (747)
Q Consensus       544 ve~G~I~~LL~LL---~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~ll----------------------ie~giI~  598 (747)
                      +..++++.|..++   . +.++.++..|+.+|..++.....     ....+                      ...++++
T Consensus       506 ~~~~~l~~L~~ll~~~~-d~~~~vR~~a~~~l~~la~~~~~-----~~~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~~  579 (1454)
T 5KC2_B          506 FVDYLLPRLKRLLISNR-QNTNYLRIVFANCLSDLAIIINR-----FQEFTFAQHCNDNSMDNNTEIMESSTKYSAKLIQ  579 (1454)
T ss_pred             HHcCcHHHHHHHHcCCC-CCcHHHHHHHHHHHHHHhcCCCC-----cceEEhhHHhhhHHHHHHHHHHHHHHHHHcCHHH
Confidence            4667888899988   7 47788899999999988754221     01111                      1245667


Q NP_000290.2     599 QIARLLQS----GNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ  674 (747)
Q Consensus       599 ~Ll~LL~s----~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e  674 (747)
                      .|..++..    .++.++..|+.+|..+.......... .++++.|..++.+      .++.++..|+.+|..|+...  
T Consensus       580 ~l~~ll~~~l~d~~~~vr~~a~~~l~~l~~~~~~~~~~-~~~l~~L~~~l~d------~~~~vR~~a~~al~~l~~~~--  650 (1454)
T 5KC2_B          580 SVEDLTVSFLTDNDTYVKMALLQNILPLCKFFGRERTN-DIILSHLITYLND------KDPALRVSLIQTISGISILL--  650 (1454)
T ss_pred             HHHHHHHhhcCCCCHHHHHHHHHHHHHHhcCcCchhHH-hhhHHHHHHHccC------CCHHHHHHHHHHHHHHHHhh--
Confidence            77777765    78899999999999987652221111 4567888888876      47899999999999998743  


Q NP_000290.2     675 LAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       675 ~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ....+++.. ++.|+.+|.+. ++.++..++.+|..|+...
T Consensus       651 ~~~~~~~~~-lp~L~~lL~d~-~~~vr~~al~aL~~L~~~~  689 (1454)
T 5KC2_B          651 GTVTLEQYI-LPLLIQTITDS-EELVVISVLQSLKSLFKTG  689 (1454)
T ss_pred             HHHHHHHcC-HHHHHHHhcCC-CHHHHHHHHHHHHHHhhCC
Confidence            333444433 88888888876 7888999999999887655


No 241
>3SL9_E Catenin beta-1, B-cell CLL/lymphoma 9; Armadillo repeat, components of the; HET: PEG, GOL, IMD, EDO; 2.2A {Homo sapiens}
Probab=94.03  E-value=0.0012  Score=55.43  Aligned_cols=110  Identities=24%  Similarity=0.309  Sum_probs=72.2  Template_Neff=12.600

Q NP_000290.2     246 TIPKAVQYLSS-QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~s-sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.. .+..++..++.++.+++.. ......+...++++.+..++...+..++..++.++.+++.........
T Consensus        56 ~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~-~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~  134 (167)
T 3SL9_E           56 MVSAIVRTMQNTNDVETARCTAGTLHNLSHH-REGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMA  134 (167)
T ss_dssp             HHHHHHHHHHHCCCHHHHHHHHHHHHHHTTS-HHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHHHHCTTHHHH
T ss_pred             hHHHHHHHHhcCCCHHHHHHHHHHHHHHcCC-HhHHHHHHHCCcHHHHHHHhCCCCHHHHHHHHHHHHHHHcCCHhHHHH
Confidence            55566666665 5667888888898888743 333333444567777888887777788888999998887654332222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNL  357 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnL  357 (747)
                      ....++++.+..++. ..++.++..++.++..+
T Consensus       135 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l  166 (167)
T 3SL9_E          135 VRLAGGLQKMVALLN-KTNVKFLAITTDCLQIL  166 (167)
T ss_dssp             HHHTTHHHHHHHHHH-HSCGGGHHHHHHHHHHH
T ss_pred             HHHcCHHHHHHHHhc-CCCHHHHHHHHHHHHHh
Confidence            222456777777776 45566777777766654


No 242
>3VWA_B Cytoplasmic export protein 1; tRNA, nuclear export, HEAT repeat; HET: MSE; 2.2A {Saccharomyces cerevisiae}
Probab=93.76  E-value=0.0017  Score=68.89  Aligned_cols=150  Identities=11%  Similarity=0.077  Sum_probs=108.5  Template_Neff=10.700

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++++.++..+. +.++.++..++.+|..++.....      . . ....+++.|..++.+.++.++..++.+|+.++..
T Consensus       379 ~~~l~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~------~-~-~~~~ll~~l~~~l~d~~~~vR~~a~~~l~~i~~~  449 (560)
T 3VWA_B          379 SRIYPHFIQGLT-DSDATLRLQTLKTIPCIVSCLTE------R-Q-LNNELLRFLAKTQVDSDVEIRTWTVIIISKISTI  449 (560)
T ss_dssp             CCCHHHHHHGGG-CSCHHHHHHHHHHHHHHGGGSCH------H-C-CCCCHHHHHHHHTTCSSHHHHHHHHHHHHHHHTT
T ss_pred             hchHHHHHHHhc-CCCHHHHHHHHHHHHHHHhhCCH------H-H-HHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHHH
Confidence            457788888887 47788999999999998864221      1 1 2356788888888888899999999999999876


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      ... .......+++.+...+.+      .++.++..|+.+|..++....  ... +...+++.|..++.+. +..++..|
T Consensus       450 ~~~~~~~~~~~l~~~l~~~l~d------~~~~vR~aa~~~l~~~~~~~~--~~~-~~~~~lp~l~~~l~d~-~~~VR~~a  519 (560)
T 3VWA_B          450 LSTSVGNRSNILATAFTKSLKD------PQVKPRLAALYGLEKSIELFD--VNT-IANKILTVIAPGLLDK-SPIVRGRA  519 (560)
T ss_dssp             SSSCHHHHHHHHHHHHHHHHTC------SSHHHHHHHHHHHHHTGGGSC--HHH-CCCCCHHHHGGGGGCS-SHHHHHHH
T ss_pred             hccccchhHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHCC--HHH-HHHHHHHHHHHHHCCC-CHHHHHHH
Confidence            211 111123455666677765      478899999999999886422  112 2245788888888877 88999999


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.+|..++..
T Consensus       520 ~~~l~~~~~~  529 (560)
T 3VWA_B          520 KILFEEYLEK  529 (560)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHH
Confidence            9999888754


No 243
>5DFZ_B Vacuolar protein sorting-associated protein 38; Vps34, Vps15, Vps30, Vps38, Autophagy; 4.4A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=93.74  E-value=0.0018  Score=77.73  Aligned_cols=155  Identities=10%  Similarity=0.029  Sum_probs=111.5  Template_Neff=9.900

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++++.|+.+|. +.++.+|..|+.+|..+......       .. .....++.|+.++.+.++.++..|+.+|..+...
T Consensus       608 ~~~l~~Li~ll~-d~~~~VR~~a~~aL~~i~~~~~~-------~~-~~~~~i~~L~~~l~d~~~~vR~~a~~aL~~~~~~  678 (1460)
T 5DFZ_B          608 DIILSHLITYLN-DKDPALRVSLIQTISGISILLGT-------VT-LEQYILPLLIQTITDSEELVVISVLQSLKSLFKT  678 (1460)
T ss_pred             HhHHHHHHHHhc-CCCHHHHHHHHHHHHHHHhhcCc-------hh-hchhHHHHHHHHhcCCCHHHHHHHHHHHHHhcCC
Confidence            357888888888 57889999999999998864221       11 1234578888899988899999999999766543


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      ......+..++++.|..++.+      .++.++..|+.+|..+.......   .....+++.|+.++.+. ++.++..|+
T Consensus       679 ~~~~~~~~~~~i~~l~~~l~d------~~~~VR~~A~~al~~l~~~~~~~---~~~~~~l~~L~~~l~d~-~~~vr~~a~  748 (1460)
T 5DFZ_B          679 GLIRKKYYIDISKTTSPLLLH------PNNWIRQFTLMIIIEIINKLSKA---EVYCILYPIIRPFFEFD-VEFNFKSMI  748 (1460)
T ss_pred             cchhhcccchhHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhCCH---HHHHHHHHHHHHHhcCC-CHHHHHHHH
Confidence            222111112367778888876      47889999999999987642111   11234688888888877 889999999


Q NP_000290.2     706 LLLSDMWSSKELQG  719 (747)
Q Consensus       706 ~aLsnL~~~~~~~~  719 (747)
                      .+|..+..+...+-
T Consensus       749 ~aL~~~~~~~~~~~  762 (1460)
T 5DFZ_B          749 SCCKQPVSRSVYNL  762 (1460)
T ss_pred             HHhCCCCCHHHHHH
Confidence            99999887776664


No 244
>6HWP_A A3_bGFPD; alphaRep, artificial protein, chimera, bidomain; 2.547A {synthetic construct}
Probab=93.71  E-value=0.0016  Score=62.80  Aligned_cols=91  Identities=14%  Similarity=0.155  Sum_probs=54.4  Template_Neff=12.900

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      ..++.+...+.+.+..++..++..+..+..           ..+++.+...+.+.++.++..++..+..+..        
T Consensus        23 ~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~-----------~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~--------   83 (409)
T 6HWP_A           23 EKVEMYIKNLQDDSYYVRRAAAYALGKIGD-----------ERAVEPLIKALKDEDAWVRRAAADALGQIGD--------   83 (409)
T ss_dssp             CCHHHHHHGGGCSSHHHHHHHHHHHHHSCC-----------GGGHHHHHHHTTCSSHHHHHHHHHHHHHHTC--------
T ss_pred             HHHHHHHHHccCCCHHHHHHHHHHHHHhcC-----------HhhHHHHHHHhcCCCHHHHHHHHHHHHHhcC--------
Confidence            445556666666677778888877776643           1234445555556667777777777766543        


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                         ...++.+...+. +.++.++..++.++..+.
T Consensus        84 ---~~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~  113 (409)
T 6HWP_A           84 ---ERAVEPLIKALK-DEDGWVRQSAAVALGQIG  113 (409)
T ss_dssp             ---GGGHHHHHHHTT-CSSHHHHHHHHHHHHHHT
T ss_pred             ---HhhHHHHHHHhc-CCCHHHHHHHHHHHHHHC
Confidence               123344445554 445566666666666554


No 245
>3TT9_A Plakophilin-2; CELL ADHESION; HET: GOL; 1.55A {Homo sapiens}
Probab=93.69  E-value=0.0017  Score=58.18  Aligned_cols=169  Identities=18%  Similarity=0.246  Sum_probs=122.4  Template_Neff=12.300

Q NP_000290.2     542 WLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLS  620 (747)
Q Consensus       542 ~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-s~d~eVr~~AL~aLs  620 (747)
                      .+++.|+++.|+.++. ..++.++..++++|.+++...+.     ....+.+.++++.|+.++. ..+..++..++++|.
T Consensus        47 ~~~~~~~i~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~  120 (233)
T 3TT9_A           47 RVNQLRGILKLLQLLK-VQNEDVQRAVCGALRNLVFEDND-----NKLEVAELNGVPRLLQVLKQTRDLETKKQITGLLW  120 (233)
T ss_dssp             HHHHTTHHHHHHHGGG-CCCHHHHHHHHHHHHHHHTTCHH-----HHHHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHH
T ss_pred             HHHHcchHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCCc-----HHHHHHHcccHHHHHHHHhhCCCHHHHHHHHHHHH
Confidence            3467788999999998 46778889999999999874332     2444456789999999998 567889999999999


Q NP_000290.2     621 NMSRHPLL-HRVMGNQVFPEVTRLLTSHTGN---------TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSM-LNNII  689 (747)
Q Consensus       621 nLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~---------~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~gi-L~~Ll  689 (747)
                      +++..... ..+...+++..+..++......         ...+..++..++++|.+++...+.....+.+.+. ++.|+
T Consensus       121 ~l~~~~~~~~~~~~~~~~~~l~~ll~~~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~  200 (233)
T 3TT9_A          121 NLSSNDKLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLV  200 (233)
T ss_dssp             HHHTSGGGHHHHHHHHHHHHCCCCCHHHHCCCGGGCCCCCTTCCHHHHHHHHHHHHHHTTSCHHHHHHHHTSTTHHHHHH
T ss_pred             HHccCHHHHHHhhhhcHHHHHHHHHhhccCCCCCCCCcccCCCcHHHHHHHHHHHHHHHhcCHHHHHHHHHcccHHHHHH
Confidence            99876433 3334455666666665431000         0014677889999999999855666666776666 88888


Q NP_000290.2     690 NLCRSSA-----SPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       690 ~LL~s~~-----d~eVr~aAL~aLsnL~~~~~  716 (747)
                      .++....     ++.++..++++|.+|+...+
T Consensus       201 ~~l~~~~~~~~~~~~~~~~~~~~L~~l~~~~~  232 (233)
T 3TT9_A          201 HYVRGTIADYQPDDKATENCVCILHNLSYQLE  232 (233)
T ss_dssp             HHHHHHHHTTCTTCHHHHHHHHHHHHHCCCCC
T ss_pred             HHHHcccccCCCChHHHHHHHHHHHHhhhccc
Confidence            8887542     46788899999999887654


No 246
>3VWA_A Cytoplasmic export protein 1; tRNA, nuclear export, HEAT repeat; 2.2A {Saccharomyces cerevisiae}
Probab=93.63  E-value=0.0019  Score=68.57  Aligned_cols=152  Identities=11%  Similarity=0.067  Sum_probs=108.9  Template_Neff=10.600

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++++.++..+. +.++.++..++.+|..++...+.      . . ....+++.|..++.+.++.++..++.+|..++.
T Consensus       378 ~~~~~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~------~-~-~~~~ll~~l~~~l~d~~~~vR~~a~~~l~~i~~  448 (560)
T 3VWA_A          378 SSRIYPHFIQGLT-DSDATLRLQTLKTIPCIVSCLTE------R-Q-LNNELLRFLAKTQVDSDVEIRTWTVIIISKIST  448 (560)
T ss_dssp             CCCCHHHHHHGGG-CSSHHHHHHHHHHHHHHGGGCCH------H-C-CCCCCHHHHHHHTTCSSHHHHHHHHHHHHHHGG
T ss_pred             HhchHHHHHHHhc-CCCHHHHHHHHHHHHHHHhhCCH------H-H-HHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHH
Confidence            3457888888887 47788999999999988864321      1 1 235678888888888889999999999999987


Q NP_000290.2     625 HPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       625 ~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                      .... .......+++.+...+.+      .++.++..|+.+|..++....  ...+ ...+++.+..++.+. +..++..
T Consensus       449 ~~~~~~~~~~~~l~~~l~~~l~d------~~~~vR~~a~~~l~~~~~~~~--~~~~-~~~ilp~l~~ll~d~-~~~VR~~  518 (560)
T 3VWA_A          449 ILSTSVGNRSNILATAFTKSLKD------PQVKPRLAALYGLEKSIELFD--VNTI-ANKILTVIAPGLLDK-SPIVRGR  518 (560)
T ss_dssp             GSSSCHHHHHHHHHHHHHHHHTC------SSHHHHHHHHHHHHHTGGGSC--HHHC-CCCCHHHHGGGGGCS-SHHHHHH
T ss_pred             HhccchhhhHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHCC--HHHH-HHHHHHHHHHHHCCC-CHHHHHH
Confidence            6211 111223455666677765      378899999999999886422  1122 235688888888877 8899999


Q NP_000290.2     704 ARLLLSDMWSSK  715 (747)
Q Consensus       704 AL~aLsnL~~~~  715 (747)
                      |+.+|..+...-
T Consensus       519 a~~~l~~i~~~l  530 (560)
T 3VWA_A          519 AKILFEEYLEKL  530 (560)
T ss_dssp             HHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHH
Confidence            999988877543


No 247
>1XQR_A HspBP1 protein; armadillo repeat, superhelical twist, CHAPERONE; HET: MSE; 2.1A {Homo sapiens} SCOP: a.118.1.21
Probab=93.61  E-value=0.0019  Score=61.69  Aligned_cols=122  Identities=15%  Similarity=0.146  Sum_probs=77.8  Template_Neff=11.300

Q NP_000290.2     257 QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVD-LLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAV  335 (747)
Q Consensus       257 sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~-lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll  335 (747)
                      .++.++..++..|..++.. ......+...++++.++. ++...++.++..++.++.+++.........+...++++.+.
T Consensus        52 ~~~~~~~~al~~L~~l~~~-~~~~~~~~~~~~~~~l~~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~l~~~~~~~~l~  130 (296)
T 1XQR_A           52 ADQQEREGALELLADLCEN-MDNAADFCQLSGMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVAAIQEQVLGLGALRKLL  130 (296)
T ss_dssp             HHHHHHHHHHHHHHHHHTS-HHHHHHHHHTTHHHHCCCCCTTCSSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHH
T ss_pred             CCHHHHHHHHHHHHHHHcC-HHHHHHHHHcccHHHHHHHHHhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHhCCHHHHHH
Confidence            4456777788888887764 333334445566777777 77776778888999999998865443333344445777777


Q NP_000290.2     336 SLLRRTG-NAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       336 ~lL~ss~-d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      .++. .. ++.++..++.++.+++..... ...+.. ++++.|+.++.
T Consensus       131 ~~l~-~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~i~~l~~~l~  177 (296)
T 1XQR_A          131 RLLD-RDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQ  177 (296)
T ss_dssp             HHHH-HCSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHH
T ss_pred             HHHh-cCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhh
Confidence            7776 33 567788888888888764322 222222 45555555543


No 248
>1XQS_B HSPBP1 protein, Heat shock 70; armadillo repeat, superhelical twist, CHAPERONE; HET: AMP; 2.9A {Homo sapiens} SCOP: a.118.1.21
Probab=93.37  E-value=0.0023  Score=59.66  Aligned_cols=123  Identities=15%  Similarity=0.159  Sum_probs=77.3  Template_Neff=11.900

Q NP_000290.2     257 QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVD-LLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAV  335 (747)
Q Consensus       257 sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~-lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll  335 (747)
                      .+..++..++..|..++.. ......+...++++.++. ++...+..++..++.++..++.........+...++++.+.
T Consensus        36 ~~~~~~~~al~~L~~l~~~-~~~~~~~~~~~~i~~l~~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~  114 (280)
T 1XQS_B           36 ADQQEREGALELLADLCEN-MDNAADFCQLSGMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVAAIQEQVLGLGALRKLL  114 (280)
T ss_dssp             HHHHHHHHHHHHHHHHHTS-HHHHHHHHHTTHHHHCCCCCTSCSCHHHHHHHHHHHHHHHTTCHHHHHHHHTTTHHHHHH
T ss_pred             cCHHHHHHHHHHHHHHHhc-HHHHHHHHHcccHHHHHHHHhhcCCHHHHHHHHHHHHHHccCCHHHHHHHHHCCHHHHHH
Confidence            4466777888888888654 233334445567777777 77766778888899999998865443333444445777777


Q NP_000290.2     336 SLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       336 ~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      .++....++.++..++.++.+++..... ...+.. ++++.|+.++.
T Consensus       115 ~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~  161 (280)
T 1XQS_B          115 RLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQ  161 (280)
T ss_dssp             HHHHSCSCHHHHHHHHHHHHHTTSSCHHHHHHHHTTTHHHHHHHHHT
T ss_pred             HHhccCCCHHHHHHHHHHHHHHHhcCHHHHHHHHHCCHHHHHHHHhh
Confidence            7775222566777888888888764322 222222 44555554443


No 249
>5VOZ_P V-type proton ATPase catalytic subunit; V-ATPase, SidK, rotational state 3;{Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=93.32  E-value=0.0027  Score=67.46  Aligned_cols=330  Identities=11%  Similarity=0.063  Sum_probs=181.1  Template_Neff=8.900

Q NP_000290.2     290 CKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTN---KLETR---RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       290 ~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~---~~~ll---~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~  362 (747)
                      ..++.++.. .+.++...++.++..++...+ .   ...++   ..+.++.++.++. . ++.++..++.+|..++... 
T Consensus        78 ~~li~LL~~~~~~d~~~~~l~~l~~ll~~~~-~~~~r~~~~~~~~~~~~~~li~lL~-~-d~~i~~~a~~~L~~L~~~~-  153 (478)
T 5VOZ_P           78 IPLIHLLSTSDNEDCKKSVQNLIAELLSSDK-YGDDTVKFFQEDPKQLEQLFDVSLK-G-DFQTVLISGFNVVSLLVQN-  153 (478)
T ss_dssp             HHHHHHHHHCCCHHHHHHHHHHHHHHHHCSS-SCHHHHHHHHHCTHHHHHHTTSTTS-S-CHHHHHHHHHHHHHHHTSS-
T ss_pred             HHHHHHHccCCCHHHHHHHHHHHHHHHcCCC-CccchhHHhccChhhHHHHHHHHcC-C-CHHHHHHHHHHHHHHHHhc-
Confidence            556666654 466777788888888876544 3   22233   2456778888886 5 6677888888888887654 


Q NP_000290.2     363 LK-EELIA-DALPV--LADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSAD  438 (747)
Q Consensus       363 ~~-~~Lve-giLe~--Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  438 (747)
                      .. ..... ++++.  ++.+|.         ++      -++++-..|..||..-+.                     .+
T Consensus       154 ~~~~~~~~~~~l~~~~li~~L~---------~~------~~~~~~~~a~~~L~~L~~---------------------~~  197 (478)
T 5VOZ_P          154 GLHNVKLVEKLLKNNNLINILQ---------NI------EQMDTCYVCIRLLQELAV---------------------IP  197 (478)
T ss_dssp             SCCCHHHHHHHHSSHHHHHHHH---------CS------SCHHHHHHHHHHHHHHTT---------------------SH
T ss_pred             cccCcccchhhcccchHHHHHh---------cc------CCccHHHHHHHHHHHHcC---------------------Ch
Confidence            32 11122 66776  777761         11      123444555555533211                     11


Q NP_000290.2     439 AGRQTMRNY-SGLIDSLMAYVQNCVAA-----------SRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYT  506 (747)
Q Consensus       439 ~~~~~~~~~-~~~~~~~~~~~~~~~~~-----------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  506 (747)
                      ..|...... .|.|..|...+.+....           ...+..-..++...|.+|++                      
T Consensus       198 ~~r~~~~~~~~g~i~~Lv~lL~~~~~~~~~~~~~~~~~~~~~~ql~~~a~~~L~~Ls~----------------------  255 (478)
T 5VOZ_P          198 EYRDVIWLHEKKFMPTLFKILQRATDSQLATRIVATNSNHLGIQLQYHSLLLIWLLTF----------------------  255 (478)
T ss_dssp             HHHHHHHHSTTSSHHHHHHHHHHHHHSCSSCCCTTTSSSHHHHHHHHHHHHHHHHHTT----------------------
T ss_pred             HHHHHHHHccccchHHHHHHHHhccccccccccccccCcCcCHHHHHHHHHHHHHHhc----------------------
Confidence            122222221 34455555444432110           00111111222222233322                      


Q NP_000290.2     507 EKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHS--DAIRTYLNLMGKSKK-DATLEACAGALQNLTASKGLMS  583 (747)
Q Consensus       507 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~--G~I~~LL~LL~ss~d-~eVr~~AL~aL~nLs~~s~~~s  583 (747)
                                                   +......+.+.  ++++.|+.+++. .. +.++..++.+|.+++...+.  
T Consensus       256 -----------------------------~~~~~~~l~~~~~~~i~~Lv~ll~~-~~kekv~r~al~~L~nL~~~~~~--  303 (478)
T 5VOZ_P          256 -----------------------------NPVFANELVQKYLSDFLDLLKLVKI-TIKEKVSRLCISIILQCCSTRVK--  303 (478)
T ss_dssp             -----------------------------SHHHHHHHHHHSHHHHGGGHHHHHH-CCCHHHHHHHHHHHHHHTSTTST--
T ss_pred             -----------------------------CHHHHHHHHHHhHHHHHHHHHHHhc-cchHHHHHHHHHHHHHHhccChH--
Confidence                                         00111223444  789999999984 44 67888899999999875321  


Q NP_000290.2     584 SG-MSQLIGLKEKGLPQIARLLQSG---NSDVVRSGASLLSNMSRH-------P------------------------LL  628 (747)
Q Consensus       584 ~~-~~~~llie~giI~~Ll~LL~s~---d~eVr~~AL~aLsnLa~~-------~------------------------e~  628 (747)
                      .. .....+...+.+..++..|...   +++++..+..++..+...       +                        +.
T Consensus       304 ~~~~~~~~l~~~~~~l~ll~~L~~~~~~d~~l~~~l~~l~~~L~~~~~~lss~dey~~el~sg~l~wsp~h~s~~f~~~n  383 (478)
T 5VOZ_P          304 QHKKVIKQLLLLGNALPTVQSLSERKYSDEELRQDISNLKEILENEYQELTSFDEYVAELDSKLLCWSPPHVDNGFWSDN  383 (478)
T ss_dssp             THHHHHHHCCCCCCHHHHHHHHTSCCCSCTHHHHHHHHHHHHHHHHHHTSCHHHHHHHHHHHTCCCCCTTTTCHHHHHHH
T ss_pred             hcHHHHHHHHHcCCHHHHHHHHHhCCCCcHHHHHHHHHHHHHHHHHHhhcCCHHHHHHHHHcCCCCCCCCcCCcChHHHh
Confidence            00 0012333444344566666543   444544433333333100       0                        01


Q NP_000290.2     629 -HRVM--GNQVFPEVTRLLTSHTGNT----SNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA  701 (747)
Q Consensus       629 -~~ll--~~giI~~Ll~LL~s~s~~~----~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr  701 (747)
                       ..+.  ..++++.|+.+|.......    ..+..++..++..|++++...+.....+.+.++++.|+.++.+. ++.++
T Consensus       384 ~~~~~~~~~~~l~~Lv~lL~~~~~~~~~~~~~~~~v~~~a~~~l~~lv~~~~~~~~~l~~~g~~~~L~~Ll~~~-~~~vr  462 (478)
T 5VOZ_P          384 IDEFKKDNYKIFRQLIELLQAKVRNGDVNAKQEKIIIQVALNDITHVVELLPESIDVLDKTGGKADIMELLNHS-DSRVK  462 (478)
T ss_dssp             HHHHTTSSSHHHHHHHHHHHHHHHSSCSSSHHHHHHHHHHHHHHHHHHHHCTTTHHHHHHHTCHHHHHHHHTSS-CHHHH
T ss_pred             HHHhhhccHHHHHHHHHHHHhhhhCCCCCccccHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHhcCC-CHHHH
Confidence             0111  2457788888886510000    01244577788899999665566666677778899999999877 88999


Q NP_000290.2     702 EAARLLLSDMWSS  714 (747)
Q Consensus       702 ~aAL~aLsnL~~~  714 (747)
                      ..|+.++.+++.+
T Consensus       463 ~~Al~al~~l~~~  475 (478)
T 5VOZ_P          463 YEALKATQAIIGY  475 (478)
T ss_dssp             HHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhh
Confidence            9999999988754


No 250
>5D80_H V-type proton ATPase catalytic subunit; Hydrolase, Autoinhibition; 6.202A {Saccharomyces cerevisiae}
Probab=93.32  E-value=0.0027  Score=67.46  Aligned_cols=330  Identities=11%  Similarity=0.063  Sum_probs=181.1  Template_Neff=8.900

Q NP_000290.2     290 CKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTN---KLETR---RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       290 ~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~---~~~ll---~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~  362 (747)
                      ..++.++.. .+.++...++.++..++...+ .   ...++   ..+.++.++.++. . ++.++..++.+|..++... 
T Consensus        78 ~~li~LL~~~~~~d~~~~~l~~l~~ll~~~~-~~~~r~~~~~~~~~~~~~~li~lL~-~-d~~i~~~a~~~L~~L~~~~-  153 (478)
T 5D80_H           78 IPLIHLLSTSDNEDCKKSVQNLIAELLSSDK-YGDDTVKFFQEDPKQLEQLFDVSLK-G-DFQTVLISGFNVVSLLVQN-  153 (478)
T ss_pred             HHHHHHHccCCCHHHHHHHHHHHHHHHcCCC-CccchhHHhccChhhHHHHHHHHcC-C-CHHHHHHHHHHHHHHHHhc-
Confidence            556666654 466777788888888876544 3   22233   2456778888886 5 6677888888888887654 


Q NP_000290.2     363 LK-EELIA-DALPV--LADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSAD  438 (747)
Q Consensus       363 ~~-~~Lve-giLe~--Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  438 (747)
                      .. ..... ++++.  ++.+|.         ++      -++++-..|..||..-+.                     .+
T Consensus       154 ~~~~~~~~~~~l~~~~li~~L~---------~~------~~~~~~~~a~~~L~~L~~---------------------~~  197 (478)
T 5D80_H          154 GLHNVKLVEKLLKNNNLINILQ---------NI------EQMDTCYVCIRLLQELAV---------------------IP  197 (478)
T ss_pred             cccCcccchhhcccchHHHHHh---------cc------CCccHHHHHHHHHHHHcC---------------------Ch
Confidence            32 11122 66776  777761         11      123444555555533211                     11


Q NP_000290.2     439 AGRQTMRNY-SGLIDSLMAYVQNCVAA-----------SRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYT  506 (747)
Q Consensus       439 ~~~~~~~~~-~~~~~~~~~~~~~~~~~-----------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  506 (747)
                      ..|...... .|.|..|...+.+....           ...+..-..++...|.+|++                      
T Consensus       198 ~~r~~~~~~~~g~i~~Lv~lL~~~~~~~~~~~~~~~~~~~~~~ql~~~a~~~L~~Ls~----------------------  255 (478)
T 5D80_H          198 EYRDVIWLHEKKFMPTLFKILQRATDSQLATRIVATNSNHLGIQLQYHSLLLIWLLTF----------------------  255 (478)
T ss_pred             HHHHHHHHccccchHHHHHHHHhccccccccccccccCcCcCHHHHHHHHHHHHHHhc----------------------
Confidence            122222221 34455555444432110           00111111222222233322                      


Q NP_000290.2     507 EKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHS--DAIRTYLNLMGKSKK-DATLEACAGALQNLTASKGLMS  583 (747)
Q Consensus       507 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~--G~I~~LL~LL~ss~d-~eVr~~AL~aL~nLs~~s~~~s  583 (747)
                                                   +......+.+.  ++++.|+.+++. .. +.++..++.+|.+++...+.  
T Consensus       256 -----------------------------~~~~~~~l~~~~~~~i~~Lv~ll~~-~~kekv~r~al~~L~nL~~~~~~--  303 (478)
T 5D80_H          256 -----------------------------NPVFANELVQKYLSDFLDLLKLVKI-TIKEKVSRLCISIILQCCSTRVK--  303 (478)
T ss_pred             -----------------------------CHHHHHHHHHHhHHHHHHHHHHHhc-cchHHHHHHHHHHHHHHhccChH--
Confidence                                         00111223444  789999999984 44 67888899999999875321  


Q NP_000290.2     584 SG-MSQLIGLKEKGLPQIARLLQSG---NSDVVRSGASLLSNMSRH-------P------------------------LL  628 (747)
Q Consensus       584 ~~-~~~~llie~giI~~Ll~LL~s~---d~eVr~~AL~aLsnLa~~-------~------------------------e~  628 (747)
                      .. .....+...+.+..++..|...   +++++..+..++..+...       +                        +.
T Consensus       304 ~~~~~~~~l~~~~~~l~ll~~L~~~~~~d~~l~~~l~~l~~~L~~~~~~lss~dey~~el~sg~l~wsp~h~s~~f~~~n  383 (478)
T 5D80_H          304 QHKKVIKQLLLLGNALPTVQSLSERKYSDEELRQDISNLKEILENEYQELTSFDEYVAELDSKLLCWSPPHVDNGFWSDN  383 (478)
T ss_pred             hcHHHHHHHHHcCCHHHHHHHHHhCCCCcHHHHHHHHHHHHHHHHHHhhcCCHHHHHHHHHcCCCCCCCCcCCcChHHHh
Confidence            00 0012333444344566666543   444544433333333100       0                        01


Q NP_000290.2     629 -HRVM--GNQVFPEVTRLLTSHTGNT----SNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA  701 (747)
Q Consensus       629 -~~ll--~~giI~~Ll~LL~s~s~~~----~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr  701 (747)
                       ..+.  ..++++.|+.+|.......    ..+..++..++..|++++...+.....+.+.++++.|+.++.+. ++.++
T Consensus       384 ~~~~~~~~~~~l~~Lv~lL~~~~~~~~~~~~~~~~v~~~a~~~l~~lv~~~~~~~~~l~~~g~~~~L~~Ll~~~-~~~vr  462 (478)
T 5D80_H          384 IDEFKKDNYKIFRQLIELLQAKVRNGDVNAKQEKIIIQVALNDITHVVELLPESIDVLDKTGGKADIMELLNHS-DSRVK  462 (478)
T ss_pred             HHHhhhccHHHHHHHHHHHHhhhhCCCCCccccHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHhcCC-CHHHH
Confidence             0111  2457788888886510000    01244577788899999665566666677778899999999877 88999


Q NP_000290.2     702 EAARLLLSDMWSS  714 (747)
Q Consensus       702 ~aAL~aLsnL~~~  714 (747)
                      ..|+.++.+++.+
T Consensus       463 ~~Al~al~~l~~~  475 (478)
T 5D80_H          463 YEALKATQAIIGY  475 (478)
T ss_pred             HHHHHHHHHHHhh
Confidence            9999999988754


No 251
>1F59_B IMPORTIN BETA-1/FXFG NUCLEOPORIN; Protein-protein complex, TRANSPORT PROTEIN RECEPTOR; 2.8A {Homo sapiens} SCOP: a.118.1.1
Probab=93.26  E-value=0.0024  Score=62.21  Aligned_cols=154  Identities=10%  Similarity=0.056  Sum_probs=84.6  Template_Neff=12.900

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLM------------SSGMSQLIG---LKEKGLPQIARLLQSG------  607 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~------------s~~~~~~ll---ie~giI~~Ll~LL~s~------  607 (747)
                      ++.++.++. +.++.++..++.++..++......            .........   .-..+++.+...+...      
T Consensus       261 ~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~l~~~~~~~~~  339 (442)
T 1F59_B          261 FAITIEAMK-SDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDD  339 (442)
T ss_dssp             HHHHHHHHH-SSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGGTSCCSSCCCCHHHHHHHHHHHHHHHHTTCCCCCCCS
T ss_pred             HHHHHHHhc-CCcHHHHHHHHHHHHHHhhHHHHHHHHHHHHHhcCCCCchhhhHHHHHHHHHHHHHHHHHHccCCCCCCC
Confidence            455666666 356677777888887776531000            000000000   0122344444444332      


Q NP_000290.2     608 -NSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSML  685 (747)
Q Consensus       608 -d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~giL  685 (747)
                       +..++..+..++..+......  .....+++.+...+.+      .++.++..++.++..+....+. ...... ..++
T Consensus       340 ~~~~~r~~a~~~l~~l~~~~~~--~~~~~~~~~l~~~l~~------~~~~~r~~al~~l~~l~~~~~~~~~~~~~-~~~~  410 (442)
T 1F59_B          340 DDWNPCKAAGVCLMLLATCCED--DIVPHVLPFIKEHIKN------PDWRYRDAAVMAFGCILEGPEPSQLKPLV-IQAM  410 (442)
T ss_dssp             SCCCHHHHHHHHHHHHHHHSTT--THHHHHHHHHHHHTTC------SSHHHHHHHHHHHHHHTSSSCHHHHHHHH-HTTH
T ss_pred             CCCcHHHHHHHHHHHHHHhccc--ccHHhHHHHHHHHhcC------CChHHHHHHHHHHHHHHhCCCHHHHHHHH-HHHH
Confidence             345667777777777654111  1112244445555544      3677888999999988865332 111111 2456


Q NP_000290.2     686 NNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       686 ~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      +.+...+.+. ++.++..++++|..++.
T Consensus       411 ~~l~~~l~d~-~~~vr~~a~~~l~~l~~  437 (442)
T 1F59_B          411 PTLIELMKDP-SVVVRDTAAWTVGRICE  437 (442)
T ss_dssp             HHHHHHTTCS-CSHHHHHHHHHHHHHHH
T ss_pred             HHHHHHhcCC-CHHHHHHHHHHHHHHHH
Confidence            6677777665 78899999999988764


No 252
>6XTE_A Importin-5, antipain; human karyopherin, PA-PB1 sub-complex nuclear; HET: FC0, OAR; 2.27A {Homo sapiens}
Probab=93.23  E-value=0.0025  Score=70.44  Aligned_cols=153  Identities=9%  Similarity=0.114  Sum_probs=85.8  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... .-..+++.+...+.+.++.++..++.++..++.. .
T Consensus       358 l~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  430 (1096)
T 6XTE_A          358 IKEHIMQMLQ-NPDWKYRHAGLMALSAIGEGCHQ-----QMEG-ILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFA  430 (1096)
T ss_dssp             HHHHHHHHHT-CSSHHHHHHHHHHHHHTHHHHTT-----TTTT-THHHHHHHHHHGGGCSSHHHHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhhHH-----HHHH-HHHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHhcc
Confidence            3444555555 35677788888888887764221     0111 1134566677777777888999999999998865 2


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSMLNNIINL--------CRSSA  696 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~giL~~Ll~L--------L~s~~  696 (747)
                      .. .......+++.+...+.+.     .+..++..++.+|..++...+. .....+ ..++..+...        +.+. 
T Consensus       431 ~~~~~~~~~~~~~~l~~~l~~~-----~~~~v~~~a~~~l~~l~~~~~~~~~~~~~-~~~~~~l~~~l~~~~~~~~~~~-  503 (1096)
T 6XTE_A          431 PGFQKKFHEKVIAALLQTMEDQ-----GNQRVQAHAAAALINFTEDCPKSLLIPYL-DNLVKHLHSIMVLKLQELIQKG-  503 (1096)
T ss_dssp             THHHHHHHHHHHHHHHHHHHTC-----SCHHHHHHHHHHHHHHHHTSCHHHHGGGH-HHHHHHHHHHHHHHHHHHHHTC-
T ss_pred             HHHHHHHHHHHHHHHHHHhccc-----CCHHHHHHHHHHHHHHhccCCHHhHHHHH-HHHHHHHHHHHHHHHHHHHHcC-
Confidence            11 1111233555566655541     2467788888888888764322 111111 1223333322        2222 


Q NP_000290.2     697 SPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       697 d~eVr~aAL~aLsnL~~~  714 (747)
                      +..++..++.++..++..
T Consensus       504 ~~~~~~~~~~~l~~l~~~  521 (1096)
T 6XTE_A          504 TKLVLEQVVTSIASVADT  521 (1096)
T ss_dssp             CCHHHHHHHHHHHHHHHH
T ss_pred             CHhHHHHHHHHHHHHHHH
Confidence            456677777777766643


No 253
>4HXT_A De Novo Protein OR329; Structural Genomics, PSI-Biology, Protein Structure; 1.95A {artificial gene}
Probab=93.20  E-value=0.0025  Score=56.21  Aligned_cols=134  Identities=25%  Similarity=0.298  Sum_probs=86.9  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++.+++...+.....+...++++.+...+.+.++.++..++.++..++..........
T Consensus        87 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  166 (252)
T 4HXT_A           87 GVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAI  166 (252)
T ss_dssp             HHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhhCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            44556666666677788888999988876543333333334567777777776677888889999988876543332333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++..... ...+.. ++++.+..++.
T Consensus       167 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  222 (252)
T 4HXT_A          167 VDAGGVEVLVKLLT-STDSEVQKEAARALANIASGPTSAIKAIVDAGGVEVLQKLLT  222 (252)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSBHHHHHHHHHTTHHHHHHHGGG
T ss_pred             HHCCHHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhc
Confidence            33456777777776 55677888889999888864322 222223 56666666654


No 254
>5IFE_C Splicing factor 3B subunit 5; pre-mRNA splicing, U2 snRNP, essential; 3.1A {Homo sapiens}
Probab=93.19  E-value=0.0029  Score=75.01  Aligned_cols=153  Identities=10%  Similarity=0.044  Sum_probs=93.2  Template_Neff=9.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.|...+. +.+..++..++.+|..++.....   . .... ....++..|...+.+.++.++..++.+|..++....
T Consensus       932 l~~~L~~~L~-~~~~~vR~~A~~~L~~l~~~~~~---~-~~~~-~~~~l~~~L~~~L~d~~~~vr~~al~aL~~l~~~~~ 1005 (1304)
T 5IFE_C          932 ICGTVLWRLN-NKSAKVRQQAADLISRTAVVMKT---C-QEEK-LMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIG 1005 (1304)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhccC---c-CHHH-HHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhhC
Confidence            4566666676 46678888999999988754221   0 0011 123456677777777777888888888888876521


Q NP_000290.2     628 L---HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       628 ~---~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      .   ...+ ..+++.|..++.+      .+..++..++.+|..++...+.....-.-..++..++..+.+. +..++..+
T Consensus      1006 ~~~l~~~l-~~ll~~L~~~L~~------~~~~Vr~~ai~~L~~i~~~~~~~~~~~~~~~il~~Ll~~l~~~-~~~vr~~a 1077 (1304)
T 5IFE_C         1006 MHKMTPPI-KDLLPRLTPILKN------RHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAH-KKAIRRAT 1077 (1304)
T ss_pred             hHHhcccH-HhHHHHHHHHhCC------CCHHHHHHHHHHHHHHHhcCcccCCHHHHHhhHHHHHHHccCC-CHHHHHHH
Confidence            1   1112 2456666677665      3577888899999888764322111000012344455555544 66788888


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.+|..++..
T Consensus      1078 ~~~L~~l~~~ 1087 (1304)
T 5IFE_C         1078 VNTFGYIAKA 1087 (1304)
T ss_pred             HHHHHHHHHH
Confidence            8888877653


No 255
>6AHD_1 Pre-mRNA-processing-splicing factor 8, Thioredoxin-like protein; Spliceosome, SPLICING; HET: IHP, GTP; 3.8A {Homo sapiens}
Probab=93.19  E-value=0.0029  Score=75.01  Aligned_cols=153  Identities=10%  Similarity=0.044  Sum_probs=93.2  Template_Neff=9.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.|...+. +.+..++..++.+|..++.....   . .... ....++..|...+.+.++.++..++.+|..++....
T Consensus       932 l~~~L~~~L~-~~~~~vR~~A~~~L~~l~~~~~~---~-~~~~-~~~~l~~~L~~~L~d~~~~vr~~al~aL~~l~~~~~ 1005 (1304)
T 6AHD_1          932 ICGTVLWRLN-NKSAKVRQQAADLISRTAVVMKT---C-QEEK-LMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIG 1005 (1304)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhccC---c-CHHH-HHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhhC
Confidence            4566666676 46678888999999988754221   0 0011 123456677777777777888888888888876521


Q NP_000290.2     628 L---HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       628 ~---~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      .   ...+ ..+++.|..++.+      .+..++..++.+|..++...+.....-.-..++..++..+.+. +..++..+
T Consensus      1006 ~~~l~~~l-~~ll~~L~~~L~~------~~~~Vr~~ai~~L~~i~~~~~~~~~~~~~~~il~~Ll~~l~~~-~~~vr~~a 1077 (1304)
T 6AHD_1         1006 MHKMTPPI-KDLLPRLTPILKN------RHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAH-KKAIRRAT 1077 (1304)
T ss_pred             hHHhcccH-HhHHHHHHHHhCC------CCHHHHHHHHHHHHHHHhcCcccCCHHHHHhhHHHHHHHccCC-CHHHHHHH
Confidence            1   1112 2456666677665      3577888899999888764322111000012344455555544 66788888


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.+|..++..
T Consensus      1078 ~~~L~~l~~~ 1087 (1304)
T 6AHD_1         1078 VNTFGYIAKA 1087 (1304)
T ss_pred             HHHHHHHHHH
Confidence            8888877653


No 256
>6QH5_B AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=93.12  E-value=0.0027  Score=64.56  Aligned_cols=146  Identities=10%  Similarity=-0.008  Sum_probs=87.6  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.++..+....++.++..++.+|..+.....       .    ....++.+...+.+.+..++..++.++..+.....
T Consensus       428 ~~~~l~~~l~~~~~~~vr~~a~~~l~~~~~~~~-------~----~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  496 (592)
T 6QH5_B          428 IIATLCENLDSLDEPDARAAMIWIVGEYAERID-------N----ADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKP  496 (592)
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHHHhCC-------C----hhhHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhCC
Confidence            556666666522456777788888887765311       0    13456667777777778899999999998876521


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      ..  +...+...+..++.+.     .++.++..+..++..+.... ......+. ..++.++..+.+. ++.++..++.+
T Consensus       497 ~~--~~~~l~~~l~~~~~~~-----~~~~vr~~a~~~l~~l~~~~-~~~~~~~~-~~~~~l~~~~~~~-~~~~~~~~~~~  566 (592)
T 6QH5_B          497 SE--TQELVQQVLSLATQDS-----DNPDLRDRGYIYWRLLSTDP-VTAKEVVL-SEKPLISEETDLI-EPTLLDELICH  566 (592)
T ss_pred             HH--hhhhhHHHHHHHcCCC-----CCHHHHHHHHHHHHHHhcCc-hhhHHHHH-hhHHHHHHHcCCC-CHHHHHHHHHH
Confidence            10  1111222222323331     25678888888888876542 21112221 2356666666555 67888888888


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      |..+...
T Consensus       567 l~~l~~~  573 (592)
T 6QH5_B          567 IGSLASV  573 (592)
T ss_pred             HHHHHHH
Confidence            8877653


No 257
>6EN4_C Splicing factor 3B subunit 3; Protein complex, splicing modulator, SPLICING; HET: BGZ; 3.08A {Homo sapiens}
Probab=92.93  E-value=0.0031  Score=67.35  Aligned_cols=154  Identities=10%  Similarity=0.023  Sum_probs=91.5  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....   . .... ....+++.+...+.+.++.++..++.++..++....
T Consensus       480 ~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~  553 (852)
T 6EN4_C          480 ICGTVLWRLN-NKSAKVRQQAADLISRTAVVMKT---C-QEEK-LMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIG  553 (852)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhChh---h-cCHH-HHHhHHHHHHHHccCCCHHHHHHHHHHHHHHHHhhC
Confidence            4556666666 46677888899999888764221   0 0001 123566777777777778888889999988876521


Q NP_000290.2     628 L--HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~--~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .  .......+++.+...+.+      .++.++..++.++..++...+...........+..++..+.+. +..++..++
T Consensus       554 ~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~vr~~a~  626 (852)
T 6EN4_C          554 MHKMTPPIKDLLPRLTPILKN------RHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAH-KKAIRRATV  626 (852)
T ss_pred             chhchhhHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhhCHHHCCHHHHHhcHHHHHHHhcCC-CHHHHHHHH
Confidence            1  111112355666666655      3567888888888888764322111000012344455555444 566777777


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .++..+...
T Consensus       627 ~~l~~l~~~  635 (852)
T 6EN4_C          627 NTFGYIAKA  635 (852)
T ss_pred             HHHHHHHHH
Confidence            777777643


No 258
>6SA6_A DARPin-Armadillo fusion A5; protein fusion, DARPin, Armadillo, shared; HET: EDO; 1.6A {synthetic construct}
Probab=92.89  E-value=0.0032  Score=61.05  Aligned_cols=112  Identities=26%  Similarity=0.312  Sum_probs=76.5  Template_Neff=12.400

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+...++.++..++.+|.+++.........+...++++.+..++...+..++..++.++..++.........+
T Consensus       284 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  363 (397)
T 6SA6_A          284 ALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAV  363 (397)
T ss_dssp             HHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCcHHHHHHHHHHHHHHhcCcHHHHHHHHhcChHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            45556666666667788888888888876544333334445677788888877777888899999998886434333334


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ...++++.+..++. ..++.++..++.++..++
T Consensus       364 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~  395 (397)
T 6SA6_A          364 KEAGALEKLEQLQS-HENEKIQKEAQEALEKLQ  395 (397)
T ss_dssp             HHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHH
T ss_pred             HHcCchHHHHHHHh-cccHHHHHHHHHHHHHHh
Confidence            44456777777776 456677777887777665


No 259
>6FT5_A A3_A3; alphaRep, artificial protein, chimera, bidomain; HET: GOL, SO4; 1.94A {synthetic construct}
Probab=92.89  E-value=0.0032  Score=60.70  Aligned_cols=91  Identities=14%  Similarity=0.155  Sum_probs=53.6  Template_Neff=12.800

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      ..++.+...+.+.+..++..++..+..+..           ...++.+...+.+.++.++..++..+..+..        
T Consensus        23 ~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~-----------~~~~~~l~~~l~~~~~~vr~~a~~~L~~~~~--------   83 (409)
T 6FT5_A           23 EKVEMYIKNLQDDSYYVRRAAAYALGKIGD-----------ERAVEPLIKALKDEDAWVRRAAADALGQIGD--------   83 (409)
T ss_pred             hHHHHHHHHhcCCCHHHHHHHHHHHHHhcC-----------cchHHHHHHHhcCCCHHHHHHHHHHHHHHcC--------
Confidence            445556666666667777777777766643           1234445555556666777777777766543        


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                         ...++.+...+. +.++.++..++.++..+.
T Consensus        84 ---~~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~  113 (409)
T 6FT5_A           84 ---ERAVEPLIKALK-DEDGWVRQSAAVALGQIG  113 (409)
T ss_pred             ---chhHHHHHHHhc-CCCHHHHHHHHHHHHhhC
Confidence               123344455554 445566666666666554


No 260
>3C5W_A PP2A A subunit, PP2A C; methylesterase, phosphatase, PP2A, HYDROLASE; 2.8A {Homo sapiens}
Probab=92.86  E-value=0.0032  Score=54.65  Aligned_cols=146  Identities=11%  Similarity=0.041  Sum_probs=96.0  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....       .. ....+++.+...+.+.++.++..++.++..+.....
T Consensus        86 ~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-------~~-~~~~~~~~l~~~~~~~~~~~r~~a~~~l~~l~~~~~  156 (232)
T 3C5W_A           86 LNSLCMAWLV-DHVYAIREAATSNLKKLVEKFGK-------EW-AHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCG  156 (232)
T ss_dssp             HHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHHCH-------HH-CCCCCHHHHHHGGGCSSHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHh-CCCHHHHHHHHHHHHHHHHHhCh-------hH-HHhcHHHHHHHHhCCCCHHHHHHHHHHHHHHHHHhC
Confidence            4566666776 46677888899998888764221       11 123566777777777778888899999988876521


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .. .....+++.+...+.+      .++.++..++.++..+....+.   ......+++.+..++.+. ++.++..++.+
T Consensus       157 ~~-~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~---~~~~~~~~~~l~~~~~~~-~~~vr~~a~~~  225 (232)
T 3C5W_A          157 QD-ITTKHMLPTVLRMAGD------PVANVRFNVAKSLQKIGPILDN---STLQSEVKPILEKLTQDQ-DVDVKYFAQEA  225 (232)
T ss_dssp             HH-HHHHHTHHHHHHGGGC------SSHHHHHHHHHHHHHHGGGSCH---HHCCCCCHHHHHHHHTCS-SHHHHHHHHHH
T ss_pred             hh-ccHhcHHHHHHHHhCC------CcHHHHHHHHHHHHHHHHHcCc---hHHHHHHHHHHHHHHhcC-CHHHHHHHHHH
Confidence            11 1122355666666665      3678888999999988764221   112234566777777765 77889989888


Q NP_000290.2     708 LSDMWS  713 (747)
Q Consensus       708 LsnL~~  713 (747)
                      |..++.
T Consensus       226 l~~l~~  231 (232)
T 3C5W_A          226 LTVLSL  231 (232)
T ss_dssp             HHHTTC
T ss_pred             HHHHhc
Confidence            887753


No 261
>4LAC_A Serine/threonine-protein phosphatase 2A activator (E.C.5.2.1.8); PP2A, PTPA, protein phosphatase, signaling; HET: AGS, MES; 2.82A {Homo sapiens}
Probab=92.86  E-value=0.0033  Score=56.30  Aligned_cols=110  Identities=11%  Similarity=0.093  Sum_probs=66.6  Template_Neff=12.800

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..+.++.|+..+. +.++.++..++.+|..+......      . . ....+++.+...+.+.++.++..++.+|..+..
T Consensus        31 ~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~------~-~-~~~~~~~~l~~~l~~~~~~vr~~~~~~l~~~~~  101 (258)
T 4LAC_A           31 SLYPIAVLIDELR-NEDVQLRLNSIKKLSTIALALGV------E-R-TRSELLPFIVELAEDAKWRVRLAIIEYMPLLAG  101 (258)
T ss_pred             cccHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHccCH------H-H-HHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHH
Confidence            3456777788887 46778888888888888754221      1 1 123456667777777777888888888887765


Q NP_000290.2     625 HPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       625 ~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      .... ......+++.+..++.+      .++.++..++.+|..++.
T Consensus       102 ~~~~-~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~  140 (258)
T 4LAC_A          102 QLGV-EYFDEKLNSLCMAWLVD------HVYAIREAATSNLKKLVE  140 (258)
T ss_pred             hCCC-hHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHH
Confidence            4111 00112234444455444      245666666666666654


No 262
>4FDD_A Transportin-1, RNA-binding protein FUS; HEAT repeats, Karyopherin, nuclear import; 2.3A {Homo sapiens}
Probab=92.57  E-value=0.0039  Score=65.83  Aligned_cols=150  Identities=10%  Similarity=0.046  Sum_probs=86.4  Template_Neff=13.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... ....+++.+...+.+.++.++..++.++..++.. .
T Consensus       360 ~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~v~~~~~~~l~~~~~~~~  432 (852)
T 4FDD_A          360 ILPLLKELLF-HHEWVVKESGILVLGAIAEGCMQ-----GMIP-YLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVV  432 (852)
T ss_dssp             HHHHHHHHHT-CSSHHHHHHHHHHHHHTTTTTHH-----HHGG-GHHHHHHHHHHHTTCSSHHHHHHHHHHHHHTHHHHH
T ss_pred             HHHHHHHHHh-CCChHHHHHHHHHHHHHHHHHHH-----hhHH-hHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHhc
Confidence            3444555555 35667777888888888764321     1111 1234666777777777788889999999888764 1


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. .......+++.+...+.+      .++.++..++.++..++........... ..++..+...+.+. +..++..++
T Consensus       433 ~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~-~~~~~~~~~  504 (852)
T 4FDD_A          433 SQPPDTYLKPLMTELLKRILD------SNKRVQEAACSAFATLEEEACTELVPYL-AYILDTLVFAFSKY-QHKNLLILY  504 (852)
T ss_dssp             HSCTTTTHHHHHHHHHHHHTC------SSHHHHHHHHHHHHHHHHHHGGGGGGGH-HHHHHHHHHHHHHC-CHHHHHHHH
T ss_pred             CCCCCcchHHHHHHHHHHHHc------CCHHHHHHHHHHHHHHHHHHHHhhHHHH-HHHHHHHHHHhhcc-CHHHHHHHH
Confidence            11 011112344555555554      2567888888888888764322111111 23455555555544 445566666


Q NP_000290.2     706 LLLSDMW  712 (747)
Q Consensus       706 ~aLsnL~  712 (747)
                      .+|..++
T Consensus       505 ~~l~~l~  511 (852)
T 4FDD_A          505 DAIGTLA  511 (852)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            6666665


No 263
>5NR4_A CLIP-associating protein 2; Microtubules, TOG domain, Tubulin, Structural; 1.198A {Homo sapiens}
Probab=92.57  E-value=0.004  Score=54.44  Aligned_cols=148  Identities=8%  Similarity=0.066  Sum_probs=97.5  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... ....+++.+...+.+.+..++..++.++..++....
T Consensus        53 ~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  125 (230)
T 5NR4_A           53 TVDALTGWVG-SSNYRVSLMGLEILSAFVDRLST-----RFKS-YVAMVIVALIDRMGDAKDKVRDEAQTLILKLMDQVA  125 (230)
T ss_dssp             HHHHHHHHHH-CSSHHHHHHHHHHHHHHHHHHGG-----GGGG-GHHHHHHHHHHHTTCSSHHHHHHHHHHHHHHHHHTS
T ss_pred             HHHHHHHHHc-CCCHHHHHHHHHHHHHHHHHhhH-----HHHH-HHHHHHHHHHHHhccCCHHHHHHHHHHHHHHHHcCC
Confidence            5566667776 46778888999999988764321     1111 123567777777777777888889999888875421


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .    ...+++.+...+.+      .++.++..++.++..++........  ....+++.+...+.+. ++.++..++.+
T Consensus       126 ~----~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~~~--~~~~~~~~l~~~l~~~-~~~vr~~a~~~  192 (230)
T 5NR4_A          126 P----PMYIWEQLASGFKH------KNFRSREGVCLCLIETLNIFGAQPL--VISKLIPHLCILFGDS-NSQVRDAAILA  192 (230)
T ss_dssp             C----HHHHHHHHGGGGGC------SCHHHHHHHHHHHHHHHHHHCSTTS--CHHHHHHHHHHHTTCS-SHHHHHHHHHH
T ss_pred             C----HHHHHHHHHhcCCC------CCHHHHHHHHHHHHHHHHHhCCCcc--cHHHHHHHHHHHHCCC-CHHHHHHHHHH
Confidence            1    11244555555554      3677888889998888764322211  1124567777777766 78899999999


Q NP_000290.2     708 LSDMWSSK  715 (747)
Q Consensus       708 LsnL~~~~  715 (747)
                      +..+....
T Consensus       193 l~~l~~~~  200 (230)
T 5NR4_A          193 IVEIYRHV  200 (230)
T ss_dssp             HHHHHHHH
T ss_pred             HHHHHHHH
Confidence            98887543


No 264
>3C5W_A PP2A A subunit, PP2A C; methylesterase, phosphatase, PP2A, HYDROLASE; 2.8A {Homo sapiens}
Probab=92.51  E-value=0.0041  Score=53.94  Aligned_cols=107  Identities=12%  Similarity=0.133  Sum_probs=62.9  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+. +.++.++..++..|..+......      . . ....+++.+...+.+.++.++..++.++..++....
T Consensus         8 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~------~-~-~~~~~~~~l~~~l~~~~~~vr~~~~~~l~~l~~~~~   78 (232)
T 3C5W_A            8 PIAVLIDELR-NEDVQLRLNSIKKLSTIALALGV------E-R-LSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLG   78 (232)
T ss_dssp             HHHHHHHHHT-CSSHHHHHHHHTTHHHHHHHHCS------S-H-CCCCCHHHHHHHTTCSSHHHHHHHHTTHHHHHHHHC
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHhCh------H-H-HHHhHHHHHHHHHhCCCHHHHHHHHHHHHHHHHhhC
Confidence            4566777776 46677888888888887754221      1 1 123556667777777777788888888887765411


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      .. .....+++.+...+.+      .++.++..++.++..++.
T Consensus        79 ~~-~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~  114 (232)
T 3C5W_A           79 VE-FFDEKLNSLCMAWLVD------HVYAIREAATSNLKKLVE  114 (232)
T ss_dssp             GG-GTTTTHHHHHHHHTTC------SSHHHHHHHHHHHHHHHH
T ss_pred             HH-HHHHHHHHHHHHHHhC------CCHHHHHHHHHHHHHHHH
Confidence            10 1111234444444444      245566666666666554


No 265
>6XU2_A Importin-5, antipain; human karyopherin, PA-PB1 sub-complex nuclear; HET: FC0, OAR; 2.834A {Homo sapiens}
Probab=92.50  E-value=0.0042  Score=68.79  Aligned_cols=152  Identities=9%  Similarity=0.112  Sum_probs=85.0  Template_Neff=12.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... .-..+++.+...+.+.++.++..++.++..++.. .
T Consensus       377 l~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  449 (1115)
T 6XU2_A          377 IKEHIMQMLQ-NPDWKYRHAGLMALSAIGEGCHQ-----QMEG-ILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFA  449 (1115)
T ss_dssp             HHHHHHHHHS-SSCSHHHHHHHHHHHHHHHHHHH-----HHTT-THHHHHHHHGGGGGCSSHHHHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhhHH-----HHHH-HHHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHhcc
Confidence            3444555555 35677788888888887764221     0111 1134566677777777888999999999988865 1


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSMLNNIINL--------CRSSA  696 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~giL~~Ll~L--------L~s~~  696 (747)
                      .. .......+++.+...+.+.     .+..++..++.+|..++...+. .....+ ..++..+...        +.+. 
T Consensus       450 ~~~~~~~~~~~~~~l~~~l~~~-----~~~~vr~~a~~~l~~l~~~~~~~~~~~~~-~~~~~~l~~~l~~~~~~~~~~~-  522 (1115)
T 6XU2_A          450 PGFQKKFHEKVIAALLQTMEDQ-----GNQRVQAHAAAALINFTEDCPKSLLIPYL-DNLVKHLHSIMVLKLQELIQKG-  522 (1115)
T ss_dssp             THHHHHHHHHHHHHHHHHHHTT-----CCHHHHHHHHHHHHHHHHTSCHHHHGGGH-HHHHHHHHHHHHHHHHHHHHTC-
T ss_pred             HHHHHHHHHHHHHHHHHHhccc-----CCHHHHHHHHHHHHHHhccCCHHhHHHHH-HHHHHHHHHHHHHHHHHHHHcC-
Confidence            11 1111223555566555431     2567788888888888764322 111111 1223333322        2222 


Q NP_000290.2     697 SPKAAEAARLLLSDMWS  713 (747)
Q Consensus       697 d~eVr~aAL~aLsnL~~  713 (747)
                      +..++..++.++..++.
T Consensus       523 ~~~~~~~~~~~l~~l~~  539 (1115)
T 6XU2_A          523 TKLVLEQVVTSIASVAD  539 (1115)
T ss_dssp             CCHHHHHHHHHHHHHHH
T ss_pred             CHhHHHHHHHHHHHHHH
Confidence            45566667777766654


No 266
>4LAC_A Serine/threonine-protein phosphatase 2A activator (E.C.5.2.1.8); PP2A, PTPA, protein phosphatase, signaling; HET: AGS, MES; 2.82A {Homo sapiens}
Probab=92.46  E-value=0.0043  Score=55.46  Aligned_cols=146  Identities=11%  Similarity=0.041  Sum_probs=96.3  Template_Neff=12.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+..++. +.++.++..++.+|..++.....       .. ....+++.+...+.+.+..++..++.++..+.....
T Consensus       112 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~-------~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  182 (258)
T 4LAC_A          112 LNSLCMAWLV-DHVYAIREAATSNLKKLVEKFGK-------EW-AHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCG  182 (258)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHcCCh-------hH-HHHhHHHHHHHHcCCCCHHHHHHHHHHHHHHHHcCC
Confidence            4566666776 46678888899999888764221       11 234567777777777778889999999888876521


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .. .....+++.+...+.+      .++.++..++.+|..+......   ......+++.+..++.+. ++.++..++.+
T Consensus       183 ~~-~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~---~~~~~~~~~~l~~~l~~~-~~~vr~~a~~~  251 (258)
T 4LAC_A          183 QD-ITTKHMLPTVLRMAGD------PVANVRFNVAKSLQKIGPILDN---STLQSEVKPILEKLTQDQ-DVDVKYFAQEA  251 (258)
T ss_pred             CC-ccHhhHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhCc---chhHHHHHHHHHHHHCCC-CHHHHHHHHHH
Confidence            11 1122355666666665      3678888999999888754221   112234566677777765 77888899888


Q NP_000290.2     708 LSDMWS  713 (747)
Q Consensus       708 LsnL~~  713 (747)
                      |..+..
T Consensus       252 l~~l~~  257 (258)
T 4LAC_A          252 LTVLSL  257 (258)
T ss_pred             HHHHHh
Confidence            887753


No 267
>6EN4_C Splicing factor 3B subunit 3; Protein complex, splicing modulator, SPLICING; HET: BGZ; 3.08A {Homo sapiens}
Probab=92.45  E-value=0.0043  Score=66.18  Aligned_cols=147  Identities=10%  Similarity=0.006  Sum_probs=89.0  Template_Neff=12.900

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.++..+. +.+..++..++.++..+....+.     ....+ -..+++.+...+.+.+..++..++.++..+....
T Consensus       675 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~  747 (852)
T 6EN4_C          675 TVLPALMNEYR-VPELNVQNGVLKSLSFLFEYIGE-----MGKDY-IYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGV  747 (852)
T ss_pred             hHHHHHHHHhC-CCCHHHHHHHHHHHHHHHhhCch-----hhHHH-HHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHcC
Confidence            35666777776 46677888899999888764321     01111 1356667777777777778888877777776541


Q NP_000290.2     627 -LLH-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       627 -e~~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                       ... ......+++.+...+.+      .++.++..++.++..+......       ...++.+...+.+. ++.++..+
T Consensus       748 ~~~~~~~~~~~~~~~l~~~~~~------~~~~~r~~~~~~l~~l~~~~~~-------~~~~~~l~~~l~~~-~~~vr~~a  813 (852)
T 6EN4_C          748 YGFGCEDSLNHLLNYVWPNVFE------TSPHVIQAVMGALEGLRVAIGP-------CRMLQYCLQGLFHP-ARKVRDVY  813 (852)
T ss_pred             ccCCcHHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhhCc-------cchHHHHHHHhCCC-cHHHHHHH
Confidence             110 00111233333333333      2567777888888777643211       23455566666655 77889999


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.++..+...
T Consensus       814 ~~~l~~l~~~  823 (852)
T 6EN4_C          814 WKIYNSIYIG  823 (852)
T ss_pred             HHHHHHHHhh
Confidence            9998888754


No 268
>1QBK_B STRUCTURE OF THE KARYOPHERIN BETA2-RAN; HEAT REPEATS, NUCLEAR TRANSPORT PROTEIN; HET: GNP; 3.0A {Homo sapiens} SCOP: a.118.1.1
Probab=92.44  E-value=0.0043  Score=66.06  Aligned_cols=151  Identities=10%  Similarity=0.047  Sum_probs=89.7  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... ....+++.+...+.+.++.++..++.++..++... 
T Consensus       398 ~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  470 (890)
T 1QBK_B          398 ILPLLKELLF-HHEWVVKESGILVLGAIAEGCMQ-----GMIP-YLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVV  470 (890)
T ss_pred             HHHHHHHHHc-CCCHHHHHHHHHHHHHHHHHhHh-----hhHh-hHHHHHHHHHHHhcCCChHHHHHHHHHHHHHHHHHc
Confidence            3445555555 35677888888888888764321     1111 12346677777777778889999999999887651 


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. .......+++.+...+.+      .++.++..++.++..++........... ..+++.+...+.+. +..++..++
T Consensus       471 ~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~-~~~~~~~~~  542 (890)
T 1QBK_B          471 SQPPDTYLKPLMTELLKRILD------SNKRVQEAACSAFATLEEEACTELVPYL-AYILDTLVFAFSKY-QHKNLLILY  542 (890)
T ss_pred             CCCCchhhHHHHHHHHHHHHC------CCHHHHHHHHHHHHHHHHHHHHhhHHHH-HHHHHHHHHHhhcc-CHHHHHHHH
Confidence            11 111112345555555554      3567888889998888764322111111 23455555555544 455666666


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .++..++.
T Consensus       543 ~~l~~l~~  550 (890)
T 1QBK_B          543 DAIGTLAD  550 (890)
T ss_pred             HHHHHHHH
Confidence            77666654


No 269
>6CRI_I Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=92.43  E-value=0.0043  Score=62.06  Aligned_cols=145  Identities=10%  Similarity=0.022  Sum_probs=87.2  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+....++.++..++.+|..+.....       .    ....++.+...+.+.++.++..++.+|..+.....
T Consensus       415 ~~~~l~~~l~~~~~~~~r~~a~~~l~~~~~~~~-------~----~~~~l~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  483 (570)
T 6CRI_I          415 VIATLCENLDSLDEPEARAAMIWIVGEYAERID-------N----ADELLESFLEGFHDKSTQVQLQLLTAIVKLFLKKP  483 (570)
T ss_dssp             THHHHTSSCTTCCCHHHHHHHHHHHHHTTTTST-------T----HHHHHHHHTTSGGGSCSHHHHHHHHHHHHHHHHCT
T ss_pred             HHHHHHHchhhCCCHHHHHHHHHHHHHHHHhcc-------C----HHHHHHHHHHccCCCCHHHHHHHHHHHHHHHhcCc
Confidence            456666666522456777788888887765311       0    13456667777777778889999999988876521


Q NP_000290.2     628 LHRVMGNQVFPEVTRL-LTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~L-L~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      . . +.. .+..++.. +.+.     .+..++..+..++..+.... ......+ ...++.++..+.+. ++.++..++.
T Consensus       484 ~-~-~~~-~~~~~l~~~~~~~-----~~~~vr~~a~~~~~~l~~~~-~~~~~~~-~~~~~~l~~~l~~~-~~~~~~~~~~  552 (570)
T 6CRI_I          484 T-E-TQE-LVQQVLSLATQDS-----DNPDLRDRGYIYWRLLSTDP-VAAKEVV-LAEKPLISEETDLI-EPTLLDELIC  552 (570)
T ss_dssp             T-T-THH-HHHHHHCCCCCSC-----CCHHHHHHHHHHHHHHHHCH-HHHHHHT-SCCCCCCCCCCCCC-CHHHHHHHHS
T ss_pred             H-H-HHH-HHHHHHHHHhcCC-----CCchHHHHHHHHHHHhcCCh-HHHHHHH-HccCCCCCccccCC-chhHHHHHHH
Confidence            1 0 111 12222222 3321     15678888888888776542 2111222 23466666666655 6788888888


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      +|..++..
T Consensus       553 ~l~~l~~~  560 (570)
T 6CRI_I          553 YIGTLASV  560 (570)
T ss_dssp             CSSBHHHH
T ss_pred             HhhcHHHH
Confidence            88887754


No 270
>2RU4_B Armadillo Repeat Protein, N-terminal fragment; solenoid repeat, Armadillo repeat motif; NMR {synthetic construct}
Probab=92.41  E-value=0.0045  Score=45.28  Aligned_cols=71  Identities=30%  Similarity=0.361  Sum_probs=42.5  Template_Neff=12.400

Q NP_000290.2     287 GGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       287 ~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ++++.+...+...+..++..+++++.+++.........+...+.+..+...+. ..++.++..++.++.+++
T Consensus        12 ~~~~~l~~~l~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~   82 (84)
T 2RU4_B           12 GALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQS-HENEKIQKEAQEALEKLQ   82 (84)
T ss_dssp             TSHHHHHHHTTCSCHHHHHHHHHHHHHHHTCSSSTTHHHHHHTCHHHHHHHTT-SSCHHHHHHHHHHHHHHC
T ss_pred             CcHHHHHHHhcCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHhc-CCCHHHHHHHHHHHHHHh
Confidence            45555666666556677788888888877653332223333445555665554 345566666777766654


No 271
>4L7M_A Putative uncharacterized protein; HEAT-repeats, Hypothetical, UNKNOWN FUNCTION; HET: MSE, GOL; 2.002A {Thermococcus onnurineus}
Probab=92.32  E-value=0.0047  Score=55.57  Aligned_cols=75  Identities=17%  Similarity=0.187  Sum_probs=52.1  Template_Neff=12.800

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      +.+.++.+...+. +.++.++..++.+|..+......   . .... .....++.|...+.+.++.++..++.+|..+..
T Consensus        35 ~~~~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~  108 (269)
T 4L7M_A           35 DKRALFLILELAG-EDDETTRLRAFVALGEILKRADS---D-LRMM-VLERHLDVFINALSQENEKVTIKALRALGYLVK  108 (269)
T ss_dssp             CHHHHHHHHHHTT-SSCHHHHHHHHHHHHHHHTTSCH---H-HHHH-HHHHHHHHHHHTCCSSSHHHHHHHHHHHHHHHT
T ss_pred             CcchHHHHHHHhC-CCCHHHHHHHHHHHHHHHhcCCH---H-HHHH-HHHhHHHHHHHHhcCCCHHHHHHHHHHHHHHHh
Confidence            4467778888887 46778888999999888764211   0 0111 123567777888887788888889998888876


Q NP_000290.2     625 H  625 (747)
Q Consensus       625 ~  625 (747)
                      .
T Consensus       109 ~  109 (269)
T 4L7M_A          109 D  109 (269)
T ss_dssp             T
T ss_pred             c
Confidence            3


No 272
>5WBJ_A Regulatory-associated protein of TOR 1,Eukaryotic; Raptor, TOS, PROTEIN BINDING; 3.0A {Arabidopsis thaliana}
Probab=92.23  E-value=0.0059  Score=72.68  Aligned_cols=100  Identities=11%  Similarity=0.096  Sum_probs=68.1  Template_Neff=8.700

Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLH-----------  629 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~-----------  629 (747)
                      ++.++..++.+|..|+...+.     ........++++.|+.+|.+.+++++..++.+|++++......           
T Consensus       612 ~~~lr~~a~~~L~~L~~~~~~-----~~~~~~~~~~~~~L~~lL~~~~~~VRaaal~aL~~li~~~~~~~~~~~~~~~~~  686 (1287)
T 5WBJ_A          612 EPLFLQWLCLCLGKLWEDFME-----AQIMGREANAFEKLAPLLSEPQPEVRAAAVFALGTLLDIGFDSNKSVVEDEFDD  686 (1287)
T ss_dssp             CHHHHHHHHHHHHHHHTTCHH-----HHHHHHHTTHHHHHGGGGGCSCHHHHHHHHHHHHHTCC------------CCCC
T ss_pred             CHHHHHHHHHHHHHHHhccHH-----HHHHHHHcCHHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCccccccccCCCCCH
Confidence            456667788888888765432     1233345678889999999889999999999999998762110           


Q NP_000290.2     630 ---RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       630 ---~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                         ..+..+++..|..++.+      .++.++..++.+|++++..
T Consensus       687 ~~~~~~~~~i~~~l~~~~~D------~S~~VR~e~~~aLs~~~~~  725 (1287)
T 5WBJ_A          687 DEKIRAEDAIIKSLLDVVSD------GSPLVRAEVAVALARFAFG  725 (1287)
T ss_dssp             CHHHHHHHHHHHHHHTTTTC------SCHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHccC------CCHHHHHHHHHHHHHHHHh
Confidence               00233455566666655      3678889999999888754


No 273
>5WBK_A Regulatory-associated protein of TOR 1,Ribosomal; Raptor, TOS, PROTEIN BINDING; 3.11A {Arabidopsis thaliana}
Probab=92.22  E-value=0.0059  Score=72.65  Aligned_cols=101  Identities=11%  Similarity=0.093  Sum_probs=68.3  Template_Neff=8.700

Q NP_000290.2     560 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLH----------  629 (747)
Q Consensus       560 ~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~----------  629 (747)
                      .++.++..++.+|..|+...+.     ........++++.|+.+|.+.+++++..++.+|+.++......          
T Consensus       611 ~~~~lr~~a~~~L~~L~~~~~~-----~~~~~~~~~~~~~L~~lL~~~~~~VRaaal~AL~~li~~~~~~~~~~~~~~~~  685 (1287)
T 5WBK_A          611 PEPLFLQWLCLCLGKLWEDFME-----AQIMGREANAFEKLAPLLSEPQPEVRAAAVFALGTLLDIGFDSNKSVVEDEFD  685 (1287)
T ss_dssp             -CHHHHHHHHHHHHHHHTTCHH-----HHHHHHTTTHHHHHGGGGGCSCHHHHHHHHHHHHHHCC------------CCC
T ss_pred             CCHHHHHHHHHHHHHHHcccHH-----HHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCccccccccCCCCC
Confidence            3456677788888888765432     1233345678889999999888999999999999998762110          


Q NP_000290.2     630 ----RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       630 ----~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                          ..+..+++..|..++.+      .++.++..++.+|++++..
T Consensus       686 ~~~~~~~~~~i~~~l~~~~~D------~s~~VR~e~~~als~~~~~  725 (1287)
T 5WBK_A          686 DDEKIRAEDAIIKSLLDVVSD------GSPLVRAEVAVALARFAFG  725 (1287)
T ss_dssp             CCHHHHHHHHHHHHHHTTTTC------SCHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHccC------CCHHHHHHHHHHHHHHHHh
Confidence                01233455566666655      3678888899999888754


No 274
>2QK2_A LP04448p; Mini spindles, Msps, XMAP215, Dis1; 2.1A {Drosophila melanogaster}
Probab=92.22  E-value=0.005  Score=54.55  Aligned_cols=145  Identities=9%  Similarity=0.135  Sum_probs=94.6  Template_Neff=12.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL-QSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL-~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      .++.+...+. +.++.++..++..|..+....+.     .... .-..+++.+...+ .+.++.++..++.+|..+... 
T Consensus        16 l~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~~~~   88 (242)
T 2QK2_A           16 MPKDFYDKLE-EKKWTLRKESLEVLEKLLTDHPK-----LENG-EYGALVSALKKVITKDSNVVLVAMAGKCLALLAKGL   88 (242)
T ss_dssp             SCTTHHHHHT-CSSHHHHHHHHHHHHHHHHHCSS-----BCCC-CCHHHHHHHHHHHHHCSCHHHHHHHHHHHHHHHHHH
T ss_pred             CCHHHHHHHh-ccchHHHHHHHHHHHHHHhhCcc-----cccc-hHHHHHHHHHHHHccCcHHHHHHHHHHHHHHHHHHh
Confidence            4566777777 47788888999999988764321     1111 1134667777777 777788999999999988865 


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      ... .... ..+++.+...+.+      .+..++..++.+|..+....+       ....++.+...+.+. ++.++..+
T Consensus        89 ~~~~~~~~-~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~~~-------~~~~~~~l~~~l~~~-~~~~r~~~  153 (242)
T 2QK2_A           89 AKRFSNYA-SACVPSLLEKFKE------KKPNVVTALREAIDAIYASTS-------LEAQQESIVESLSNK-NPSVKSET  153 (242)
T ss_dssp             GGGGHHHH-HHHHHHHHHGGGC------CCHHHHHHHHHHHHHHHTTSC-------HHHHHHHHHHHTTCS-CHHHHHHH
T ss_pred             hHhHHHHH-HhHHHHHHHHHhc------CCHHHHHHHHHHHHHHHHcCC-------HHHHHHHHHHHHcCC-CHHHHHHH
Confidence            211 1111 2356666666665      356788888888888875421       112455566666655 67778888


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.++..++..
T Consensus       154 ~~~l~~l~~~  163 (242)
T 2QK2_A          154 ALFIARALTR  163 (242)
T ss_dssp             HHHHHHHHTT
T ss_pred             HHHHHHHHHh
Confidence            8887777653


No 275
>3W3U_A Importin subunit beta-3; HEAT repeat, nuclear import, PROTEIN; 2.6A {Saccharomyces cerevisiae}
Probab=92.21  E-value=0.005  Score=67.54  Aligned_cols=115  Identities=14%  Similarity=0.059  Sum_probs=64.9  Template_Neff=13.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .+++.+...+.+.++.++..++.++..+...............+++.+...+. +.+..++..++.++..++........
T Consensus       397 ~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~~~~~~~~~  476 (1078)
T 3W3U_A          397 KILDMVIPLINDPHPRVQYGCCKVLGQISTAFSPFIQRTAHDRILPALISKLTSECTSRVQTHAAAALVAFSEFASKDIL  476 (1078)
T ss_dssp             HHHHHHGGGGGCSSHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHHHSSTTSCHHHHHHHHHHHHHHHTTCCHHHH
T ss_pred             HHHHHHHHHccCCCHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHcCCCCCHHHHHHHHHHHHHHHHhCChhhh
Confidence            34444455555566778888888888876543221111111234555555555 34566777788888777654322111


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ......++..+...+. ..++.++..++.++..++..
T Consensus       477 ~~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  512 (1078)
T 3W3U_A          477 EPYLDSLLTNLLVLLQ-SNKLYVQEQALTTIAFIAEA  512 (1078)
T ss_dssp             GGGHHHHHHHHHHHHT-CSSHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHH
Confidence            1111245555666665 44567778888888877754


No 276
>2IW3_B ELONGATION FACTOR 3A; ACETYLATION, ATP-BINDING, ELONGATION FACTOR, PROTEIN; HET: MSE, ADP, SO4; 2.4A {SACCHAROMYCES CEREVISIAE}
Probab=92.03  E-value=0.0058  Score=68.10  Aligned_cols=148  Identities=16%  Similarity=0.128  Sum_probs=74.2  Template_Neff=11.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.|..++. +.+..++..|+.+|..++.....       ..  ....++.++..+.+.+.  ...++..+..+.....
T Consensus       176 i~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~-------~~--~~~~~~~l~~~l~~~~~--~~~~~~~l~~~~~~~~  243 (986)
T 2IW3_B          176 LIPVLSETMW-DTKKEVKAAATAAMTKATETVDN-------KD--IERFIPSLIQCIADPTE--VPETVHLLGATTFVAE  243 (986)
T ss_dssp             HHHHHHHHTT-CSCHHHHHHHHHHHHHHGGGCCS-------ST--TGGGHHHHHHHHHCGGG--HHHHHHHHTTCCCCSC
T ss_pred             HHHHHHHhcC-cCCHHHHHHHHHHHHHHHHhcCc-------HH--HHHHHHHHHHHhcCccc--chHHHHHHHHchhhcc
Confidence            5566667776 45667777888888777653211       11  12344455555543322  2222323222222110


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK-QYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~-~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ........+++.+...+.+      .++.++..++.++..++........ ......+++.|+.++.+..++.++..++.
T Consensus       244 ~~~~~~~~~l~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~i~~~l~~~l~d~~d~~vr~~a~~  317 (986)
T 2IW3_B          244 VTPATLSIMVPLLSRGLNE------RETGIKRKSAVIIDNMCKLVEDPQVIAPFLGKLLPGLKSNFATIADPEAREVTLR  317 (986)
T ss_dssp             CCHHHHHHHHHHHHHHHTS------SSHHHHHHHHHHHHHHHTTCCCHHHHHHHHTTTHHHHHHHHHHCCCHHHHHHHHH
T ss_pred             cCHHHHHhHHHHHHHhccc------ccccccHHHHHHHHHHHHHhcCHhHHHHHHHHHHHHHHHhhcCCCCHHHHHHHHH
Confidence            0000011245555555554      3567778888888877754211100 00112356666666665423677777777


Q NP_000290.2     707 LLSDMWS  713 (747)
Q Consensus       707 aLsnL~~  713 (747)
                      +|..+..
T Consensus       318 ~l~~l~~  324 (986)
T 2IW3_B          318 ALKTLRR  324 (986)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            7777643


No 277
>4G3A_B CLIP-associating protein; TOG domain, HEAT repeat, MAP; HET: GOL; 1.994A {Drosophila melanogaster}
Probab=91.94  E-value=0.0059  Score=54.01  Aligned_cols=150  Identities=10%  Similarity=0.094  Sum_probs=93.1  Template_Neff=12.600

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.++..+. +.++.++..++..|..++.....   . .... ....+++.+...+.+.++.++..++.++..++...
T Consensus         7 ~~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~---~-~~~~-~~~~~~~~l~~~l~d~~~~v~~~a~~~l~~l~~~~   80 (237)
T 4G3A_B            7 SDLDGFIQQMP-KADMRVKVQLAEDLVTFLSDDTN---S-IVCT-DMGFLIDGLMPWLTGSHFKIAQKSLEAFSELIKRL   80 (237)
T ss_dssp             SSHHHHHHHST-TCCHHHHHHHHHHHHHHHHCTTS---C-CCCS-CHHHHHHHHGGGGSSSCHHHHHHHHHHHHHHHHHH
T ss_pred             chHHHHHHhcC-cCCHHHHHHHHHHHHHHhhCCCC---C-cccc-cHHHHHHHHHHHhcCCcHHHHHHHHHHHHHHHHHh
Confidence            35666777777 46778888999999888764221   0 0111 12345677777777778889999999999988652


Q NP_000290.2     627 L-LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNII-NLCRSSASPKAAEAA  704 (747)
Q Consensus       627 e-~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll-~LL~s~~d~eVr~aA  704 (747)
                      . ........+++.++..+.+      .+..++..++.+|..+........     ...++.+. .++.+. ++.++..+
T Consensus        81 ~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~~~~~~-----~~~~~~l~~~~l~~~-~~~~r~~a  148 (237)
T 4G3A_B           81 GSDFNAYTATVLPHVIDRLGD------SRDTVREKAQLLLRDLMEHRVLPP-----QALIDKLATSCFKHK-NAKVREEF  148 (237)
T ss_dssp             GGGGGGTHHHHHHHHHHHHTC------SCHHHHHHHHHHHHHHHHTTSSCH-----HHHHHHHHHHHTTCS-CHHHHHHH
T ss_pred             hhhHHHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHcCCCCH-----HHHHHHHHHHHhhCC-CHHHHHHH
Confidence            1 1111112356666666655      356788888888888875311111     12345555 555544 56677777


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.++..++..
T Consensus       149 ~~~l~~l~~~  158 (237)
T 4G3A_B          149 LQTIVNALHE  158 (237)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHH
Confidence            7777776644


No 278
>5EWP_B Uncharacterized protein; translocation and attachment of rhoptries; 1.8A {Plasmodium falciparum Santa Lucia}
Probab=91.92  E-value=0.0062  Score=55.67  Aligned_cols=176  Identities=16%  Similarity=0.152  Sum_probs=134.6  Template_Neff=11.800

Q NP_000290.2     528 CPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDAT----------------LEACAGALQNLTASK--GLMSSGMSQL  589 (747)
Q Consensus       528 ~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eV----------------r~~AL~aL~nLs~~s--~~~s~~~~~~  589 (747)
                      +-+++++++++.+..+++.|+++.|+.+|.. .+...                +..++++|.+++...  +.     ...
T Consensus         7 ~~~~~~~~~~~~~~~~~~~g~i~~L~~ll~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~-----~~~   80 (252)
T 5EWP_B            7 KLLSFTSNDILRFDKAYDENDVQEFVNLCSS-TCEIEKLEDRMHPWAADPKTIGALSATQLAILASKENEPH-----YKD   80 (252)
T ss_dssp             --CCCCCHHHHHHHHHHHTTCHHHHHHHTTC-CCBCCCC--CCCSSSCCCCBHHHHHHHHHHHHHTCTTCTH-----HHH
T ss_pred             HHHhccHHHHhhhHHHHhcCCHHHHHHHhcC-CChHHHHHHHhhhhhCCHHHHHHHHHHHHHHHhcCCCCHH-----HHH
Confidence            4456899999999999999999999999983 33222                236888888888652  21     244


Q NP_000290.2     590 IGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRN  667 (747)
Q Consensus       590 llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsn  667 (747)
                      .+.+.++++.|+.++...++.++..++++|.+++.. ... ..+...++++.++.++..      .++.++..++++|.+
T Consensus        81 ~~~~~g~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~  154 (252)
T 5EWP_B           81 AIREANGIAVFINLLKSHELDRVHAAVVALSFLSVDNVKNCICMFESGALPYLISGMKS------NIDGMKAACAQTCRN  154 (252)
T ss_dssp             HHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTTCHHHHHHHHHTTCHHHHHHHTTC------SCHHHHHHHHHHHHH
T ss_pred             HHHHcccHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHhhC------CCHHHHHHHHHHHHH
Confidence            445778999999999888888999999999999986 443 344556788888888875      367889999999999


Q NP_000290.2     668 LMASQPQLAKQYFSSSMLNNIINLCRSSASP-------KAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       668 La~~s~e~~~~Lve~giL~~Ll~LL~s~~d~-------eVr~aAL~aLsnL~~~~~  716 (747)
                      ++...+.....+.+.++++.|+.++... +.       .++..++.+|.+++...+
T Consensus       155 l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~~~~a~~~l~~l~~~~~  209 (252)
T 5EWP_B          155 IFVLDKKYKKEFLKLGGITQLVNLLELP-SNYDDSQPLYTQLEAIYHLEDFILNDG  209 (252)
T ss_dssp             HHTTCHHHHHHHHHTTHHHHHHHTTSCC-TTCCSCSCCHHHHHHHHHHHHHHEETT
T ss_pred             HHhcCHHHHHHHHHCChHHHHHHHhcCC-CCCCCCchHHHHHHHHHHHHHHHhcCC
Confidence            9875455666677778889999988765 33       378889999999987665


No 279
>4QMI_B Cytoskeleton-associated protein 5; PROTEIN BINDING, TOG domain; 1.9A {Homo sapiens}
Probab=91.92  E-value=0.006  Score=54.09  Aligned_cols=147  Identities=7%  Similarity=-0.004  Sum_probs=97.2  Template_Neff=12.600

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... .....++.++..+.+.+..++..++.++..+.....
T Consensus        60 ~~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  132 (240)
T 4QMI_B           60 LPTALKGRLN-DSNKILVQQTLNILQQLAVAMGP-----NIKQ-HVKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTG  132 (240)
T ss_dssp             HHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHHGG-----GGGG-GCCCCCHHHHHHTTCSSHHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHhcH-----HHHH-HHHHHHHHHHHHhhcCCHHHHHHHHHHHHHHHHHhC
Confidence            4566666676 46778888999999988764321     1111 123466777777777778888889999888875421


Q NP_000290.2     628 LHRVMGNQVF--PEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI--~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .     ..++  +.+...+.+      .++.++..++.+|..++...... ... -..+++.+...+.+. +..++..++
T Consensus       133 ~-----~~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~-~~~-~~~~~~~l~~~l~~~-~~~vr~~a~  198 (240)
T 4QMI_B          133 M-----KEWLEGEDLSEELKK------ENPFLRQELLGWLAEKLPTLRST-PTD-LILCVPHLYSCLEDR-NGDVRKKAQ  198 (240)
T ss_dssp             S-----HHHHSSSHHHHHHTS------CCHHHHHHHHHHHHHHGGGCSSC-CGG-GGGGHHHHHHHTTCS-SHHHHHHHH
T ss_pred             h-----hHhccHHHHHHHHhc------CCHHHHHHHHHHHHHHHHhCCCC-cHH-HHHHHHHHHHHHhcC-CHHHHHHHH
Confidence            1     1234  555666655      36788888999998877543221 111 124567777777766 788999999


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .++..+....
T Consensus       199 ~~l~~l~~~~  208 (240)
T 4QMI_B          199 DALPFFMMHL  208 (240)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHh
Confidence            9998887653


No 280
>4QMJ_A Cytoskeleton-associated protein 5; PROTEIN BINDING, TOG DOMAIN; 2.498A {Homo sapiens}
Probab=91.92  E-value=0.006  Score=54.09  Aligned_cols=147  Identities=7%  Similarity=-0.004  Sum_probs=97.2  Template_Neff=12.600

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... .....++.++..+.+.+..++..++.++..+.....
T Consensus        60 ~~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  132 (240)
T 4QMJ_A           60 LPTALKGRLN-DSNKILVQQTLNILQQLAVAMGP-----NIKQ-HVKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTG  132 (240)
T ss_dssp             HHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHHGG-----GGGG-GCCCCCHHHHHGGGCSSHHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHhcH-----HHHH-HHHHHHHHHHHHhhcCCHHHHHHHHHHHHHHHHHhC
Confidence            4566666676 46778888999999988764321     1111 123466777777777778888889999888875421


Q NP_000290.2     628 LHRVMGNQVF--PEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI--~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .     ..++  +.+...+.+      .++.++..++.+|..++...... ... -..+++.+...+.+. +..++..++
T Consensus       133 ~-----~~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~-~~~-~~~~~~~l~~~l~~~-~~~vr~~a~  198 (240)
T 4QMJ_A          133 M-----KEWLEGEDLSEELKK------ENPFLRQELLGWLAEKLPTLRST-PTD-LILCVPHLYSCLEDR-NGDVRKKAQ  198 (240)
T ss_dssp             S-----HHHHSSSHHHHHHHS------SCHHHHHHHHHHHHHHGGGCSCC-CGG-GGGGHHHHHHHTTCS-SHHHHHHHH
T ss_pred             h-----hHhccHHHHHHHHhc------CCHHHHHHHHHHHHHHHHhCCCC-cHH-HHHHHHHHHHHHhcC-CHHHHHHHH
Confidence            1     1234  555666655      36788888999998877543221 111 124567777777766 788999999


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .++..+....
T Consensus       199 ~~l~~l~~~~  208 (240)
T 4QMJ_A          199 DALPFFMMHL  208 (240)
T ss_dssp             HTHHHHHHHH
T ss_pred             HHHHHHHHHh
Confidence            9998887653


No 281
>5XAH_A Importin-4; Histone, Chromatin, Assembly, PROTEIN TRANSPORT; HET: MSE; 3.004A {Homo sapiens}
Probab=91.84  E-value=0.0062  Score=58.52  Aligned_cols=153  Identities=14%  Similarity=0.074  Sum_probs=87.5  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      +++.+...+. +.++.++..++.+|..++.....     ....+ -..+++.+...+. +.++.++..++.++..++...
T Consensus       235 ~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-----~~~~~-~~~i~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~  307 (416)
T 5XAH_A          235 LLPVLLSTAQ-EADPEVRSNAIFGMGVLAEHGGH-----PAQEH-FPKLLGLLFPLLARERHDRVRDNICGALARLLMAS  307 (416)
T ss_dssp             HHHHHHHHTS-CSSHHHHHHHHHHHHHHHHHHHH-----HHHTT-HHHHHHHHTTHHHHCCCHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHHHHhh-cCCHHHHHHHHHHHHHHHHhcCc-----hHHhh-HHHHHHHHHHHhccCCCHHHHHHHHHHHHHHHHhC
Confidence            4556666666 35677888888888888764321     11111 1346677777777 567788999999999888652


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA-SPKAAEAAR  705 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~-d~eVr~aAL  705 (747)
                      .... ....+++.+...+...    ......+. ++.++..+....+......+ ..+++.+...+.+.. ...++..++
T Consensus       308 ~~~~-~~~~~~~~l~~~l~~~----~~~~~~~~-~~~~l~~l~~~~~~~~~~~~-~~i~~~l~~~l~~~~~~~~~r~~~~  380 (416)
T 5XAH_A          308 PTRK-PEPQVLAALLHALPLK----EDLEEWVT-IGRLFSFLYQSSPDQVIDVA-PELLRICSLILADNKIPPDTKAALL  380 (416)
T ss_dssp             CSSC-CCHHHHHHHHHHCSCC----SCTTHHHH-HHHHHHHHHHHCSTTGGGSH-HHHHHTGGGTSSCTTSCHHHHHHHH
T ss_pred             CCCC-CHHHHHHHHHHhCCCC----CchhhHHH-HHHHHHHHHhcCchHHHhhH-HHHHHHHHHHHcCCCCCHHHHHHHH
Confidence            1110 1123455555555221    01344555 77777777764332211111 134555666555431 235778888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .++..+...
T Consensus       381 ~~l~~l~~~  389 (416)
T 5XAH_A          381 LLLTFLAKQ  389 (416)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHh
Confidence            888877643


No 282
>5XAH_C Importin-4; Histone, Chromatin, Assembly, PROTEIN TRANSPORT; HET: MSE; 3.004A {Homo sapiens}
Probab=91.84  E-value=0.0062  Score=58.52  Aligned_cols=153  Identities=14%  Similarity=0.074  Sum_probs=87.3  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      +++.+...+. +.++.++..++.+|..++.....     ....+ -..+++.+...+. +.++.++..++.++..++...
T Consensus       235 ~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-----~~~~~-~~~i~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~  307 (416)
T 5XAH_C          235 LLPVLLSTAQ-EADPEVRSNAIFGMGVLAEHGGH-----PAQEH-FPKLLGLLFPLLARERHDRVRDNICGALARLLMAS  307 (416)
T ss_dssp             HHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHSHH-----HHHTT-HHHHHHHHTHHHHHCCCHHHHHHHHHHHHHHHHTS
T ss_pred             HHHHHHHHhh-cCCHHHHHHHHHHHHHHHHhcCc-----hHHhh-HHHHHHHHHHHhccCCCHHHHHHHHHHHHHHHHhC
Confidence            4556666666 35677888888888888764321     11111 1346677777777 567788999999999888652


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA-SPKAAEAAR  705 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~-d~eVr~aAL  705 (747)
                      .... ....+++.+...+...    ......+. ++.++..+....+......+ ..+++.+...+.+.. ...++..++
T Consensus       308 ~~~~-~~~~~~~~l~~~l~~~----~~~~~~~~-~~~~l~~l~~~~~~~~~~~~-~~i~~~l~~~l~~~~~~~~~r~~~~  380 (416)
T 5XAH_C          308 PTRK-PEPQVLAALLHALPLK----EDLEEWVT-IGRLFSFLYQSSPDQVIDVA-PELLRICSLILADNKIPPDTKAALL  380 (416)
T ss_dssp             CC---CCHHHHHHHHHHCSCC----SCGGGHHH-HHHHHHHHHHHCHHHHTTTH-HHHHHHHHHHHSCTTSCHHHHHHHH
T ss_pred             CCCC-CHHHHHHHHHHhCCCC----CchhhHHH-HHHHHHHHHhcCchHHHhhH-HHHHHHHHHHHcCCCCCHHHHHHHH
Confidence            1110 1123455555555221    01344555 77777777764332211111 134555666555431 235778888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .++..+...
T Consensus       381 ~~l~~l~~~  389 (416)
T 5XAH_C          381 LLLTFLAKQ  389 (416)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHh
Confidence            888877643


No 283
>2QK1_A Protein STU2; stu2, Stu2p, XMAP215, Dis1, TOG; 1.7A {Saccharomyces cerevisiae}
Probab=91.81  E-value=0.0063  Score=53.79  Aligned_cols=152  Identities=9%  Similarity=0.052  Sum_probs=95.7  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQN-LTASKGLMSSGMSQ--LIGLKEKGLPQIARLL-QSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~n-Ls~~s~~~s~~~~~--~llie~giI~~Ll~LL-~s~d~eVr~~AL~aLsnLa  623 (747)
                      .++.+...+. +.++.++..++..|.. ++.....     ..  .. ....+++.+...+ .+.++.++..++.++..++
T Consensus        17 l~~~l~~~l~-~~~~~~r~~a~~~l~~~l~~~~~~-----~~~~~~-~~~~~~~~l~~~l~~d~~~~vr~~a~~~l~~l~   89 (249)
T 2QK1_A           17 LPKDFQERIT-SSKWKDRVEALEEFWDSVLSQTKK-----LKSTSQ-NYSNLLGIYGHIIQKDANIQAVALAAQSVELIC   89 (249)
T ss_dssp             SCTTHHHHHT-CSSHHHHHHHHHHHHHHTGGGCCC-----BCCTTC-CCHHHHHHHHHHHHHCSCHHHHHHHHHHHHHHH
T ss_pred             CCHHHHHHHh-CCCHHHHHHHHHHHHHHHHhcCCC-----cCCCCc-cHHHHHHHHHHHHhhCcHHHHHHHHHHHHHHHH
Confidence            4556666676 4677888899999998 7754221     01  01 1245677777888 7778889999999999888


Q NP_000290.2     624 RH-PL-LHR-VMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL-AKQYFSSSMLNNIINLCRSSASPK  699 (747)
Q Consensus       624 ~~-~e-~~~-ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~-~~~Lve~giL~~Ll~LL~s~~d~e  699 (747)
                      .. .. ... .....+++.++..+.+      .+..++..++.++..+....+.. ..... ..+++.+...+.+. ++.
T Consensus        90 ~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~~~~~~~~~~~~~~~-~~~~~~l~~~l~~~-~~~  161 (249)
T 2QK1_A           90 DKLKTPGFSKDYVSLVFTPLLDRTKE------KKPSVIEAIRKALLTICKYYDPLASSGRN-EDMLKDILEHMKHK-TPQ  161 (249)
T ss_dssp             HHHCTTTSCHHHHHHHHHHHHHGGGC------CCHHHHHHHHHHHHHHHHHSCTTCTTCTT-HHHHHHHHHHTTCS-SHH
T ss_pred             HHcCCCCCCHHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhChhcccCCH-HHHHHHHHHHhCCC-CHH
Confidence            65 22 111 1122355666666655      35678888888888887542210 00111 23566666666655 677


Q NP_000290.2     700 AAEAARLLLSDMWSS  714 (747)
Q Consensus       700 Vr~aAL~aLsnL~~~  714 (747)
                      ++..++.++..+...
T Consensus       162 vr~~~~~~l~~~~~~  176 (249)
T 2QK1_A          162 IRMECTQLFNASMKE  176 (249)
T ss_dssp             HHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHh
Confidence            888888888777654


No 284
>5H2V_A Importin subunit beta-3, Ubiquitin-like-specific protease; nuclear import, PROTEIN TRANSPORT-HYDROLASE complex; 2.8A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=91.79  E-value=0.0063  Score=66.66  Aligned_cols=114  Identities=16%  Similarity=0.088  Sum_probs=64.4  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+.++.++..++.++..+...............+++.+...+.+ .+..++..++.++..++.........
T Consensus       398 ~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~  477 (1078)
T 5H2V_A          398 ILDMVIPLINDPHPRVQYGCCNVLGQISTDFSPFIQRTAHDRILPALISKLTSECTSRVQTHAAAALVNFSEFASKDILE  477 (1078)
T ss_dssp             HHHHHGGGGGCSSHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHHTTSTTSCHHHHHHHHHHHHHHHTTCCHHHHG
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHHhhccHHHHHHHHHhHHHHHHHHcccCCCHHHHHHHHHHHHHHHhcCChhhHH
Confidence            34444445555566778888888887765432211101113455555555554 45677788888888777543221101


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      .....++..+...+. ..++.++..++.++..++..
T Consensus       478 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  512 (1078)
T 5H2V_A          478 PYLDSLLTNLLVLLQ-SNKLYVQEQALTTIAFIAEA  512 (1078)
T ss_dssp             GGHHHHHHHHHHHTT-CSSHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHh-CCCHHHHHHHHHHHHHHHHH
Confidence            111245555666654 44566778888888877654


No 285
>6OWT_A AP-2 complex subunit alpha, AP-2; AP, HIV, Nef, trafficking, Protein;{Rattus norvegicus}
Probab=91.69  E-value=0.0072  Score=67.72  Aligned_cols=142  Identities=13%  Similarity=0.056  Sum_probs=80.2  Template_Neff=11.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSD--VVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~e--Vr~~AL~aLsnLa~~  625 (747)
                      .++.++.++. +.+..++..++.++..+......          ....+++.+...+.+.+..  ++..++++|+.+...
T Consensus       442 ~~~~l~~~l~-~~~~~v~~~a~~~l~~i~~~~~~----------~~~~~~~~l~~~l~~~~~~~~v~~~a~~~L~~~~~~  510 (939)
T 6OWT_A          442 YVDTILNLIR-IAGDYVSEEVWYRVIQIVINRDD----------VQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNL  510 (939)
T ss_pred             HHHHHHHHhC-CCChhcCHHHHHHHHHHHhcCHH----------HHHhHHHHHHHHhcCCCCcHHHHHHHHHHHHHHHHh
Confidence            5666777776 35556777777777776643211          1234556666667654444  778888888877654


Q NP_000290.2     626 P-LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLC---RSSASPKAA  701 (747)
Q Consensus       626 ~-e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL---~s~~d~eVr  701 (747)
                      . .........++..|...+..      .+..++..++.+|..++...+..      ...+..++..+   .+. +.+++
T Consensus       511 ~~~~~~~~~~~~~~~L~~~l~~------~~~~vr~~al~aL~~l~~~~~~~------~~~i~~ll~~l~~~~~~-d~evr  577 (939)
T 6OWT_A          511 IAGDPRSSPLIQFNLLHSKFHL------CSVPTRALLLSTYIKFVNLFPEV------KATIQDVLRSDSQLKNA-DVELQ  577 (939)
T ss_pred             cCCCCCCCHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhChhh------HhHHHHHHHHhcccCCC-CHHHH
Confidence            1 11100111244455555554      25677888888888887643221      12334444433   333 66777


Q NP_000290.2     702 EAARLLLSDMWS  713 (747)
Q Consensus       702 ~aAL~aLsnL~~  713 (747)
                      ..++.++..+..
T Consensus       578 ~~a~~~l~~l~~  589 (939)
T 6OWT_A          578 QRAVEYLRLSTV  589 (939)
T ss_pred             HHHHHHHHHHcC
Confidence            777777766553


No 286
>2P8Q_A Importin beta-1 subunit, Snurportin-1; HEAT repeat, IBB-domain, Importin, Karyopherin; 2.35A {Homo sapiens} SCOP: a.118.1.1
Probab=91.69  E-value=0.0066  Score=64.52  Aligned_cols=160  Identities=8%  Similarity=0.007  Sum_probs=89.0  Template_Neff=13.100

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG--NSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~--d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.++..+..+.++.++..++.+|..++.....     ....+ -..+++.+...+.+.  ++.++..++.++..++..
T Consensus       650 ~~~~l~~~l~~~~~~~vr~~~~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~~~v~~~a~~~l~~l~~~  723 (876)
T 2P8Q_A          650 FKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQS-----NIIPF-CDEVMQLLLENLGNENVHRSVKPQILSVFGDIALA  723 (876)
T ss_dssp             HHHHHHHHHHCCSSHHHHHHHHHHHHHHHHHHGG-----GGHHH-HHHHHHHHHHHTSCSSSCTTHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHhccccHHHHHHHHHHHHHHHHHHhh-----cchHh-HHHHHHHHHHHHcCcCcccchHhHHHHHHHHHHHH
Confidence            3455555555225667888888888888754221     01111 135677777777766  678888999999888865


Q NP_000290.2     626 -PLL-HRVMGNQVFPEVTRLLTSHTG-----NTSNSEDILSSACYTVRNLMASQPQLAKQYFS-----SSMLNNIINLCR  693 (747)
Q Consensus       626 -~e~-~~ll~~giI~~Ll~LL~s~s~-----~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve-----~giL~~Ll~LL~  693 (747)
                       ... ..++ ..+++.+...+.....     ....+..++..++.++..++.........+..     ...++.++..+.
T Consensus       724 ~~~~~~~~~-~~~~~~l~~~l~~~~~~~~~~~~~~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~  802 (876)
T 2P8Q_A          724 IGGEFKKYL-EVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFID  802 (876)
T ss_dssp             HGGGGHHHH-HHHHHHHHHHHSCCCCTTCSTTHHHHHHHHHHHHHHHHHHHHHHSCSSCSCCCGGGGTGGGHHHHHHHHH
T ss_pred             hchhhHHHH-HHHHHHHHHHHHccCCCCchHHHHHHHHHHHHHHHHHHHHHHHHhcCcccCCCchhhHHHhHHHHHHHHH
Confidence             211 1111 2345555555443100     00014667888888888887621111111100     011444444443


Q NP_000290.2     694 ------SSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       694 ------s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                            +. +..++..++.++..++..-
T Consensus       803 ~~~~~~~~-~~~v~~~~~~~l~~l~~~~  829 (876)
T 2P8Q_A          803 HIAGDEDH-TDGVVACAAGLIGDLCTAF  829 (876)
T ss_dssp             HHHHSSCC-CHHHHHHHHHHHHHHHHHH
T ss_pred             HHhCCCCC-ChhHHHHHHHHHHHHHHHh
Confidence                  33 5778888888888877543


No 287
>5MFO_F YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: CA, EDO; 1.3A {synthetic construct}
Probab=91.65  E-value=0.0068  Score=51.30  Aligned_cols=157  Identities=18%  Similarity=0.285  Sum_probs=121.2  Template_Neff=13.100

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .+.++.++..+. +.++.++..++..|.+++...+.     ....+.+.++++.|..++.+.++.++..++++|.+++..
T Consensus         3 ~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~   76 (202)
T 5MFO_F            3 GSELPQMVQQLN-SPDQQELQSALRKLSQIASGGNE-----QIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASG   76 (202)
T ss_dssp             CTTHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHH-----HHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTS
T ss_pred             CchHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCChH-----HHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHhcC
Confidence            456788888887 47778888999999999875332     233445678899999999988889999999999999976


Q NP_000290.2     626 -PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       626 -~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                       ... ..+...++++.+..++.+      .++.++..++.+|.+++...+.....+.+.++++.+..++.+. +..++..
T Consensus        77 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~  149 (202)
T 5MFO_F           77 GNEQIQAVIDAGALPALVQLLSS------PNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSP-NEQILQE  149 (202)
T ss_dssp             CHHHHHHHHHTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCS-CHHHHHH
T ss_pred             CHHHHHHHHHCChHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCC-CHHHHHH
Confidence             333 334455678888888866      3678888999999999876455555556667888888888866 7888999


Q NP_000290.2     704 ARLLLSDMWSSK  715 (747)
Q Consensus       704 AL~aLsnL~~~~  715 (747)
                      ++.+|.+++...
T Consensus       150 ~~~~l~~l~~~~  161 (202)
T 5MFO_F          150 ALWALSNIASGG  161 (202)
T ss_dssp             HHHHHHHHTTSC
T ss_pred             HHHHHHHHhcCh
Confidence            999999998765


No 288
>5MFO_E YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: EDO, CA; 1.3A {synthetic construct}
Probab=91.58  E-value=0.007  Score=51.19  Aligned_cols=157  Identities=18%  Similarity=0.285  Sum_probs=120.0  Template_Neff=13.100

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .+.++.++..+. +.++.++..++..|.+++...+.     ....+.+.++++.|..++.+.++.++..++++|.+++..
T Consensus         3 ~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~   76 (202)
T 5MFO_E            3 GSELPQMVQQLN-SPDQQELQSALRKLSQIASGGNE-----QIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASG   76 (202)
T ss_dssp             --CHHHHHHHTT-CSSHHHHHHHHHHHHHHHTSCHH-----HHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTS
T ss_pred             CchHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCChH-----HHHHHHHCChHHHHHHHhhCCCHHHHHHHHHHHHHHhcC
Confidence            456788888887 47778888999999999875332     233445678899999999988889999999999999976


Q NP_000290.2     626 -PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       626 -~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                       +.. ..+...++++.+...+.+      .++.++..++.+|.+++...+.....+.+.++++.+..++.+. +..++..
T Consensus        77 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~  149 (202)
T 5MFO_E           77 GNEQIQAVIDAGALPALVQLLSS------PNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSP-NEQILQE  149 (202)
T ss_dssp             CHHHHHHHHHTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCS-CHHHHHH
T ss_pred             CHHHHHHHHHCChHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCC-CHHHHHH
Confidence             333 333455678888888866      3678888999999999876455555555667888888888876 7888999


Q NP_000290.2     704 ARLLLSDMWSSK  715 (747)
Q Consensus       704 AL~aLsnL~~~~  715 (747)
                      ++.+|.+++...
T Consensus       150 ~~~~l~~l~~~~  161 (202)
T 5MFO_E          150 ALWALSNIASGG  161 (202)
T ss_dssp             HHHHHHHHHTSC
T ss_pred             HHHHHHHHhcCH
Confidence            999999998765


No 289
>2QNA_A Importin subunit beta-1, Snurportin-1; Nuclear transport, import of spliceosomal; HET: SO4; 2.84A {Homo sapiens}
Probab=91.50  E-value=0.0073  Score=62.82  Aligned_cols=159  Identities=8%  Similarity=0.020  Sum_probs=86.8  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG--NSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~--d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+...+....++.++..++.++..++.....     ....+ -..+++.+...+.+.  ++.++..++.++..++..
T Consensus       525 ~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~-~~~i~~~l~~~l~~~~~~~~v~~~~~~~l~~l~~~  598 (762)
T 2QNA_A          525 FKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQS-----NIIPF-CDEVMQLLLENLGNENVHRSVKPQILSVFGDIALA  598 (762)
T ss_pred             HHHHHHHHhCCCCCHHHHHHHHHHHHHHHHHhHH-----cchHh-HHhHHHHHHHHHcCCCCCHHHHHHHHHHHHHHHHH
Confidence            4555665565224567788888888888754221     01111 135667777777765  567888899999888765


Q NP_000290.2     626 -PLL-HRVMGNQVFPEVTRLLTSHTGN-----TSNSEDILSSACYTVRNLMASQPQLAKQYFS-----SSMLNNIINLCR  693 (747)
Q Consensus       626 -~e~-~~ll~~giI~~Ll~LL~s~s~~-----~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve-----~giL~~Ll~LL~  693 (747)
                       ... ..++ ..+++.+...+......     ...+..++..++.++..++...+.....+..     ...++.++.++.
T Consensus       599 ~~~~~~~~~-~~i~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~l~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~  677 (762)
T 2QNA_A          599 IGGEFKKYL-EVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFID  677 (762)
T ss_pred             hhcchHHHH-HHHHHHHHHHHcCCCCCCCcccCCCCHHHHHHHHHHHHHHHHhCCCCCcCccccHHHHHhHHHHHHHHHH
Confidence             211 1111 23445555554421000     0014566778888888887642221111100     011344444443


Q NP_000290.2     694 ------SSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       694 ------s~~d~eVr~aAL~aLsnL~~~  714 (747)
                            +. +..++..++.+|..++..
T Consensus       678 ~~~~~~~~-~~~~~~~a~~~l~~l~~~  703 (762)
T 2QNA_A          678 HIAGDEDH-TDGVVACAAGLIGDLCTA  703 (762)
T ss_pred             HHcCCCCC-CHHHHHHHHHHHHHHHHH
Confidence                  22 467788888888887754


No 290
>6G4J_B Probable serine/threonine-protein kinase YabT (E.C.2.7.11.1); Bacterial Hanks-type protein kinase, complex; 1.599A {Bacillus subtilis (strain 168)}
Probab=91.47  E-value=0.008  Score=50.62  Aligned_cols=132  Identities=14%  Similarity=0.147  Sum_probs=85.5  Template_Neff=11.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      ..+.+++++. +.++.++..++..+..+..                ...++.+..++.+.++.++..++.++..+...  
T Consensus        15 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~----------------~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~--   75 (148)
T 6G4J_B           15 KVEMYIKNLQ-DDSAVVRDYAAAALGKIGD----------------ERAVEPLIKALKDEDEYVRQSAAWALGEIGDE--   75 (148)
T ss_pred             cHHHHHHHhc-CCCHHHHHHHHHHHHhhCC----------------HHHHHHHHHHhCCCCHHHHHHHHHHHHHhCCH--
Confidence            4566777777 4667777777777765532                12344556667677788888888888877542  


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                             ..++.+...+.+      .++.++..++.++..+...           ..++.+..++.+. ++.++..++.+
T Consensus        76 -------~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~vr~~a~~~  130 (148)
T 6G4J_B           76 -------RAVEPLIKALKD------EDPSVRLTAAEALGQIGGE-----------RVRAAMEKLAETG-TGFARKVAVNY  130 (148)
T ss_pred             -------HHHHHHHHHhcC------CCHHHHHHHHHHHHhhCCH-----------HHHHHHHHHhcCC-CHHHHHHHHHH
Confidence                   234455555554      3567888888888876531           2344555566555 67888999999


Q NP_000290.2     708 LSDMWSSKELQGVLRQ  723 (747)
Q Consensus       708 LsnL~~~~~~~~~~~~  723 (747)
                      |..+........-+++
T Consensus       131 L~~~~~~~~~~~~~~~  146 (148)
T 6G4J_B          131 LETHKSLISGGGGSGG  146 (148)
T ss_pred             HHhhCCCChHhccccc
Confidence            9888766555444443


No 291
>3W3W_A Importin subunit beta-3, Protein STE12; HEAT repeat, nuclear import, PROTEIN; 2.2A {Saccharomyces cerevisiae}
Probab=91.29  E-value=0.0081  Score=65.72  Aligned_cols=98  Identities=9%  Similarity=0.152  Sum_probs=58.6  Template_Neff=13.000

Q NP_000290.2     609 SDVVRSGASLLSNMSRHPL-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLN  686 (747)
Q Consensus       609 ~eVr~~AL~aLsnLa~~~e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~  686 (747)
                      ..++..++.++..++.... . .... ..+++.+...+.+      .++.++..++.+|..++...+...... ...+++
T Consensus       821 ~~~~~~~~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~------~~~~~r~~a~~~l~~l~~~~~~~~~~~-~~~~~~  892 (1078)
T 3W3W_A          821 EDLLDEINKSIAAVLKTTNGHYLKNL-ENIWPMINTFLLD------NEPILVIFALVVIGDLIQYGGEQTASM-KNAFIP  892 (1078)
T ss_dssp             HHHHHHHHHHHHHHHHHHTTTHHHHH-GGGHHHHHHHHC--------CHHHHHHHHHHHHHHHTC--CCCHHH-HHHHHH
T ss_pred             HHHHHHHHHHHHHHHHhcccchHHHH-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhcchhhHHH-HHhHHH
Confidence            3455666677776665411 1 1111 2345556666554      356788888899988876432221111 124567


Q NP_000290.2     687 NIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       687 ~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      .+...+.+. ++.++..++.+|..++...
T Consensus       893 ~l~~~l~~~-~~~vr~~a~~~l~~l~~~~  920 (1078)
T 3W3W_A          893 KVTECLISP-DARIRQAASYIIGVCAQYA  920 (1078)
T ss_dssp             HHHHHHTCS-CHHHHHHHHHHHHHHHHHS
T ss_pred             HHHHHhcCC-CHHHHHHHHHHHHHHHHHC
Confidence            777777766 7889999999998888653


No 292
>3ND2_A Importin subunit beta-1; importin, karyopherin, nuclear import, receptor; 2.4A {Saccharomyces cerevisiae}
Probab=91.23  E-value=0.0083  Score=63.25  Aligned_cols=152  Identities=13%  Similarity=0.136  Sum_probs=86.1  Template_Neff=13.300

Q NP_000290.2     548 AIRTYLNLMGKSKK-DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d-~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      .++.+...+.. .+ ..++..++.++..++.....     .... .-..+++.+...+.+.++.++..++.++..++.. 
T Consensus       598 ~~~~l~~~l~~-~~~~~v~~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~  670 (861)
T 3ND2_A          598 LMGLFFRLLEK-KDSAFIEDDVFYAISALAASLGK-----GFEK-YLETFSPYLLKALNQVDSPVSITAVGFIADISNSL  670 (861)
T ss_dssp             HHHHHHHHHHS-TTHHHHHHHHHHHHHHHHHHHGG-----GGGG-GHHHHHHHHHHHHTCTTSTHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHhc-CCCchhHHHHHHHHHHHHHHhhh-----hHHH-HHHhHHHHHHHHHcCCCchHHHHHHHHHHHHHHHc
Confidence            45555666652 33 55777888888887754221     0111 1235677777777777778888999999988865 


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASP------  698 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~------  698 (747)
                      +.. .... ..+++.+...+...    ..+..++..++.++..++...+....... ..+++.+...+... ..      
T Consensus       671 ~~~~~~~~-~~~~~~l~~~l~~~----~~~~~~r~~a~~~l~~l~~~~~~~~~~~~-~~i~~~l~~~l~~~-~~~~~~~~  743 (861)
T 3ND2_A          671 EEDFRRYS-DAMMNVLAQMISNP----NARRELKPAVLSVFGDIASNIGADFIPYL-NDIMALCVAAQNTK-PENGTLEA  743 (861)
T ss_dssp             TTSSHHHH-HHHHHHHHHHHHCT----TCCTTHHHHHHHHHHHHHHHHGGGGGGGH-HHHHHHHHHHHTCC-CSSSSHHH
T ss_pred             chhhHHhH-HHHHHHHHHHHhCc----chhhhhHHHHHHHHHHHHHHcchhcHHHH-HHHHHHHHHHHccC-CCCCCHHH
Confidence            211 1111 23555555555541    01467788888999888765332111111 23455555555433 21      


Q NP_000290.2     699 -----KAAEAARLLLSDMWS  713 (747)
Q Consensus       699 -----eVr~aAL~aLsnL~~  713 (747)
                           .++..++.++..++.
T Consensus       744 ~~~~~~~~~~~l~~l~~~~~  763 (861)
T 3ND2_A          744 LDYQIKVLEAVLDAYVGIVA  763 (861)
T ss_dssp             HHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHHH
Confidence                 455566666655443


No 293
>5OWU_A Importin subunit beta-1, Nucleoporin NUP1; nuclear transport, TRANSPORT PROTEIN; 2.0A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=91.23  E-value=0.0083  Score=63.25  Aligned_cols=152  Identities=13%  Similarity=0.136  Sum_probs=86.1  Template_Neff=13.300

Q NP_000290.2     548 AIRTYLNLMGKSKK-DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d-~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      .++.+...+.. .+ ..++..++.++..++.....     .... .-..+++.+...+.+.++.++..++.++..++.. 
T Consensus       598 ~~~~l~~~l~~-~~~~~v~~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~  670 (861)
T 5OWU_A          598 LMGLFFRLLEK-KDSAFIEDDVFYAISALAASLGK-----GFEK-YLETFSPYLLKALNQVDSPVSITAVGFIADISNSL  670 (861)
T ss_dssp             HHHHHHHHHHS-TTGGGTHHHHHHHHHHHHHHHGG-----GGGG-GHHHHHHHHHHHHHCTTSTHHHHHHHHHHHHHHHS
T ss_pred             HHHHHHHHHhc-CCCchhHHHHHHHHHHHHHHhhh-----hHHH-HHHhHHHHHHHHHcCCCchHHHHHHHHHHHHHHHc
Confidence            45555666652 33 55777888888887754221     0111 1235677777777777778888999999988865 


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASP------  698 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~------  698 (747)
                      +.. .... ..+++.+...+...    ..+..++..++.++..++...+....... ..+++.+...+... ..      
T Consensus       671 ~~~~~~~~-~~~~~~l~~~l~~~----~~~~~~r~~a~~~l~~l~~~~~~~~~~~~-~~i~~~l~~~l~~~-~~~~~~~~  743 (861)
T 5OWU_A          671 EEDFRRYS-DAMMNVLAQMISNP----NARRELKPAVLSVFGDIASNIGADFIPYL-NDIMALCVAAQNTK-PENGTLEA  743 (861)
T ss_dssp             GGGGHHHH-HHHHHHHHHHHTCT----TCCTTHHHHHHHHHHHHHHHHGGGGHHHH-HHHHHHHHHHHTCC-CSSSSHHH
T ss_pred             chhhHHhH-HHHHHHHHHHHhCc----chhhhhHHHHHHHHHHHHHHcchhcHHHH-HHHHHHHHHHHccC-CCCCCHHH
Confidence            211 1111 23555555555541    01467788888999888765332111111 23455555555433 21      


Q NP_000290.2     699 -----KAAEAARLLLSDMWS  713 (747)
Q Consensus       699 -----eVr~aAL~aLsnL~~  713 (747)
                           .++..++.++..++.
T Consensus       744 ~~~~~~~~~~~l~~l~~~~~  763 (861)
T 5OWU_A          744 LDYQIKVLEAVLDAYVGIVA  763 (861)
T ss_dssp             HHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHHH
Confidence                 455566666655443


No 294
>5DFZ_B Vacuolar protein sorting-associated protein 38; Vps34, Vps15, Vps30, Vps38, Autophagy; 4.4A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=90.97  E-value=0.011  Score=70.63  Aligned_cols=159  Identities=14%  Similarity=0.083  Sum_probs=104.1  Template_Neff=9.900

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATL-EACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL---QSGNSDVVRSGASLLSN  621 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr-~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL---~s~d~eVr~~AL~aLsn  621 (747)
                      ..+++.|+.+|. +.++.++ ..|+.+|..+......   ......+...++++.|+.+|   .+.++.++..++.+|..
T Consensus       463 ~~~i~~L~~~l~-d~~~~vR~~~a~~~L~~l~~~~~~---~~~~~~~~~~~~lp~Li~~L~~~~d~~~~vr~~aa~~l~~  538 (1460)
T 5DFZ_B          463 DRVVPYFVCCFE-DSDQDVQALSLLTLIQVLTSVRKL---NQLNENIFVDYLLPRLKRLLISNRQNTNYLRIVFANCLSD  538 (1460)
T ss_pred             ccchHHHHHHhc-CCCHHHHHHHHHHHHHHhcCCCCc---cCCccccCcCChHHHHHHHHHhccCCCHHHHHHHHHHHHH
Confidence            457888999998 5788888 8999999988764221   00011223467899999999   88889999999999998


Q NP_000290.2     622 MSRHP--L-----------L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNN  687 (747)
Q Consensus       622 La~~~--e-----------~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~  687 (747)
                      +....  .           . ...+..++++.+..++...-  ...++.++..|+.+|..|+......   .....+++.
T Consensus       539 ~~~~~~~~~l~~l~~~~~~~~~~~l~~~~~~~l~~ll~~~l--~d~~~~VR~~A~~aL~~l~~~~~~~---~~~~~~l~~  613 (1460)
T 5DFZ_B          539 LAIIINRFQEFTFAQHCNDNSSTKYSAKLIQSVEDLTVSFL--TDNDTYVKMALLQNILPLCKFFGRE---RTNDIILSH  613 (1460)
T ss_pred             HHHHcCHHHHHHHHHhcccChhHHHHcChHHHHHHHHHHHh--cCCCHHHHHHHHHHHHHHhcccccc---ccHHhHHHH
Confidence            85430  0           0 01122234444444433200  0036789999999999987542111   111356778


Q NP_000290.2     688 IINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       688 Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      |+.++.+. ++.+|..|+.+|..+...
T Consensus       614 Li~ll~d~-~~~VR~~a~~aL~~i~~~  639 (1460)
T 5DFZ_B          614 LITYLNDK-DPALRVSLIQTISGISIL  639 (1460)
T ss_pred             HHHHhcCC-CHHHHHHHHHHHHHHHhh
Confidence            88888776 788888888888888763


No 295
>3W3U_A Importin subunit beta-3; HEAT repeat, nuclear import, PROTEIN; 2.6A {Saccharomyces cerevisiae}
Probab=90.68  E-value=0.011  Score=64.69  Aligned_cols=157  Identities=9%  Similarity=0.025  Sum_probs=84.5  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.++..+..+.+..++..++.+|..++.....   . .... .-..+++.+...+.+.++.++..++.+|..++....
T Consensus       440 ~~~~l~~~l~~~~~~~vr~~a~~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~  514 (1078)
T 3W3U_A          440 ILPALISKLTSECTSRVQTHAAAALVAFSEFASK---D-ILEP-YLDSLLTNLLVLLQSNKLYVQEQALTTIAFIAEAAK  514 (1078)
T ss_dssp             HHHHHHHHSSTTSCHHHHHHHHHHHHHHHTTCCH---H-HHGG-GHHHHHHHHHHHHTCSSHHHHHHHHHHHHHHHHHHG
T ss_pred             HHHHHHHHcCCCCCHHHHHHHHHHHHHHHHhCCh---h-hhHH-HHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHhH
Confidence            4555666665224566777888888888764221   0 0111 123566677777777778888899999988876521


Q NP_000290.2     628 -LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR---SSASPKAAEA  703 (747)
Q Consensus       628 -~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~---s~~d~eVr~a  703 (747)
                       ........+++.+...+....   ..++.++..++.++..+................++.+..++.   +. +..++..
T Consensus       515 ~~~~~~~~~~~~~l~~~l~~~~---~~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~-~~~~~~~  590 (1078)
T 3W3U_A          515 NKFIKYYDTLMPLLLNVLKVNN---KDNSVLKGKCMECATLIGFAVGKEKFHEHSQELISILVALQNSDIDE-DDALRSY  590 (1078)
T ss_dssp             GGGGGGHHHHHHHHHHHHHCC-------HHHHHHHHHHHHHHHHHHCHHHHTTTHHHHHHHHHHHHTSSCCC-CHHHHHH
T ss_pred             HhHHHHHhhHHHHHHHHHhcCC---CCcchHHHHHHHHHHHHHHHHCHHHhHHHHHHHHHHHHHHhcCCCCC-CHHHHHH
Confidence             111111234555555554310   014567777888888776532111100011123444444444   23 4566777


Q NP_000290.2     704 ARLLLSDMWS  713 (747)
Q Consensus       704 AL~aLsnL~~  713 (747)
                      ++.++..++.
T Consensus       591 ~~~~l~~l~~  600 (1078)
T 3W3U_A          591 LEQSWSRICR  600 (1078)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHH
Confidence            7777766654


No 296
>1QGR_A IMPORTIN BETA SUBUNIT, IMPORTIN ALPHA-2; TRANSPORT RECEPTOR, NUCLEAR IMPORT, HEAT; 2.3A {Homo sapiens} SCOP: a.118.1.1
Probab=90.57  E-value=0.011  Score=62.78  Aligned_cols=113  Identities=11%  Similarity=0.140  Sum_probs=66.6  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL-E  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~-~  324 (747)
                      +++.+...+.+.++.++..++.++..++..............+++.+...+.+.+..++..++.++..++........ .
T Consensus       367 ~~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~  446 (876)
T 1QGR_A          367 VLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAIND  446 (876)
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHHHcCCHHhcHHHHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHHhCChhhcCC
Confidence            344444555556677788888888887764322111111234556666666666778888899998888764432110 1


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      .....+++.+...+. + ++.++..++.++..+...
T Consensus       447 ~~~~~~~~~l~~~l~-~-~~~v~~~a~~~l~~l~~~  480 (876)
T 1QGR_A          447 VYLAPLLQCLIEGLS-A-EPRVASNVCWAFSSLAEA  480 (876)
T ss_pred             chHHHHHHHHHHHhc-C-CHHHHHHHHHHHHHHHHH
Confidence            112245566666665 3 566777777777777653


No 297
>4QMH_A LP04448p; PROTEIN BINDING, TOG DOMAIN; 1.652A {Drosophila melanogaster}
Probab=90.39  E-value=0.012  Score=51.77  Aligned_cols=149  Identities=9%  Similarity=0.047  Sum_probs=95.9  Template_Neff=12.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... .-..+++.+...+.+.+..++..++.+|..++....
T Consensus        58 ~~~~l~~~l~-d~~~~v~~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  130 (241)
T 4QMH_A           58 LAPALAHRLV-DSNAKIAQTTLAICEQLATAMGA-----GCRN-HVRNLFPGFLHALGDNKSFVRAAALNCINSFGEKGG  130 (241)
T ss_dssp             HHHHHHHHHT-CSSHHHHHHHHHHHHHHHHHHGG-----GGGG-GHHHHHHHHHHHTTCSSHHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHHHHHc-CCCHHHHHHHHHHHHHHHHHhcH-----HHHH-HHHHHHHHHHHHhcCCcHHHHHHHHHHHHHHHHhcC
Confidence            4556666676 46778888999999988764221     1111 113566777777777777788888888888775421


Q NP_000290.2     628 LHRVMGNQVFPE--VTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK-QYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       628 ~~~ll~~giI~~--Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~-~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      .     ..+++.  +...+.+      .++.++..++.++..++...+.... ......+++.+...+.+. ++.++..+
T Consensus       131 ~-----~~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~vr~~a  198 (241)
T 4QMH_A          131 Y-----KEFFESEMIADALKG------GSPALKTELWAWLADKLPGLPPKSVSKEDIHSMVPHLYAHICDR-NADVRKNA  198 (241)
T ss_dssp             S-----GGGSSTTHHHHHHHT------CCHHHHHHHHHHHHHHGGGSCGGGSCHHHHHHHHHHHHHHTTCS-SHHHHHHH
T ss_pred             h-----HHhcCHHHHHHHHhC------CCHHHHHHHHHHHHHhccCCCcccCCHHHHHhHHHHHHHHHhCC-CHHHHHHH
Confidence            1     123333  5555554      3677888899999888764322110 011124567777777766 78899999


Q NP_000290.2     705 RLLLSDMWSSK  715 (747)
Q Consensus       705 L~aLsnL~~~~  715 (747)
                      +.++..+....
T Consensus       199 ~~~l~~l~~~~  209 (241)
T 4QMH_A          199 NEAVLGIMIHL  209 (241)
T ss_dssp             HHHHHHHHHHH
T ss_pred             HHHHHHHHHHh
Confidence            99998887543


No 298
>5A1V_E ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT; TRANSPORT PROTEIN, COPI, COATOMER, COATED; 21.0A {SACCHAROMYCES CEREVISIAE}
Probab=90.35  E-value=0.013  Score=64.93  Aligned_cols=102  Identities=12%  Similarity=0.008  Sum_probs=64.4  Template_Neff=10.900

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..++..+...+.+.+..++..+..++..+....+..      ..+++.+...+.+.+..++..++.++..+....     
T Consensus        67 ~~l~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~------~~i~~~l~~~L~~~~~~vr~~al~~L~~~~~~~-----  135 (874)
T 5A1V_E           67 TEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDV------IIVTSSLTKDMTGKEDNYRGPAVRALCQITDST-----  135 (874)
T ss_dssp             HHHHHHHHHGGGSCCHHHHHHHHHHHHHHHTSCSCG------GGHHHHHHHHHHSSSHHHHHHHHHHHHHHCCHH-----
T ss_pred             HHHHHHHHHHHcCCCHHHHHHHHHHHHHhcccCchH------hHHHHHHHHhcCCCChhhHHHHHHHHhhcCCHH-----
Confidence            345556666677777788888888887776532211      234555666666667778888888887664211     


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                        ....++..+...+. +.++.++..++.++..+..
T Consensus       136 --~~~~l~~~l~~~l~-d~~~~Vr~~a~~~l~~l~~  168 (874)
T 5A1V_E          136 --MLQAVERYMKQAIV-DKVPSVSSSALVSSLHLLK  168 (874)
T ss_dssp             --HHHHHHHHHHHHHT-CSSHHHHHHHHHHHHHHHH
T ss_pred             --HHHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHh
Confidence              01234455555665 5567788888888887765


No 299
>5NZR_G Coatomer subunit alpha, Coatomer subunit; COPI, coatomer, coated vesicles, Transport; 9.2A {Mus musculus}
Probab=90.35  E-value=0.013  Score=64.93  Aligned_cols=102  Identities=12%  Similarity=0.008  Sum_probs=64.4  Template_Neff=10.900

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..++..+...+.+.+..++..+..++..+....+..      ..+++.+...+.+.+..++..++.++..+....     
T Consensus        67 ~~l~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~------~~i~~~l~~~L~~~~~~vr~~al~~L~~~~~~~-----  135 (874)
T 5NZR_G           67 TEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDV------IIVTSSLTKDMTGKEDNYRGPAVRALCQITDST-----  135 (874)
T ss_pred             HHHHHHHHHHHcCCCHHHHHHHHHHHHHhcccCchH------hHHHHHHHHhcCCCChhhHHHHHHHHhhcCCHH-----
Confidence            345556666677777788888888887776532211      234555666666667778888888887664211     


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                        ....++..+...+. +.++.++..++.++..+..
T Consensus       136 --~~~~l~~~l~~~l~-d~~~~Vr~~a~~~l~~l~~  168 (874)
T 5NZR_G          136 --MLQAVERYMKQAIV-DKVPSVSSSALVSSLHLLK  168 (874)
T ss_pred             --HHHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHh
Confidence              01234455555665 5567788888888887765


No 300
>3W3W_A Importin subunit beta-3, Protein STE12; HEAT repeat, nuclear import, PROTEIN; 2.2A {Saccharomyces cerevisiae}
Probab=90.26  E-value=0.013  Score=64.05  Aligned_cols=157  Identities=10%  Similarity=0.054  Sum_probs=83.5  Template_Neff=13.000

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.++..+....++.++..++.+|..++.....   . .... .-..+++.+...+.+.++.++..++.++..++...
T Consensus       439 ~~~~~l~~~l~~~~~~~~r~~a~~~l~~l~~~~~~---~-~~~~-~~~~i~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~  513 (1078)
T 3W3W_A          439 RILPALISKLTSECTSRVQTHAAAALVNFSEFASK---D-ILEP-YLDSLLTNLLVLLQSNKLYVQEQALTTIAFIAEAA  513 (1078)
T ss_dssp             HHHHHHHHHTSTTSCHHHHHHHHHHHHHHHHTCCH---H-HHGG-GHHHHHHHHHHHHTCSSHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHcccCCCHHHHHHHHHHHHHHHhcCCh---h-hHHH-HHHHHHHHHHHHHhcCCHHHHHHHHHHHHHHHHHh
Confidence            35566666665224567778888888887764221   0 0011 11355666777777667788888999998887652


Q NP_000290.2     627 L-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP-QLAKQYFSSSMLNNIINLCR---SSASPKA  700 (747)
Q Consensus       627 e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~-e~~~~Lve~giL~~Ll~LL~---s~~d~eV  700 (747)
                      . . .... ..+++.+...+....   ..++.++..++.++..++.... ...... ...++..+...+.   +. +..+
T Consensus       514 ~~~~~~~~-~~~~~~l~~~l~~~~---~~~~~~~~~~~~~l~~l~~~~~~~~~~~~-~~~~~~~l~~~l~~~~~~-~~~v  587 (1078)
T 3W3W_A          514 KNKFIKYY-DTLMPLLLNVLKVNN---KDNSVLKGKCMECATLIGFAVGKEKFHEH-SQELISILVALQNSDIDE-DDAL  587 (1078)
T ss_dssp             GGGGGGGH-HHHHHHHHHHHHCC-------HHHHHHHHHHHHHHHHHHCHHHHTTT-HHHHHHHHHHHHTCC------HH
T ss_pred             HHhHHHHH-HhHHHHHHHHHHhCC---CCChHHHHHHHHHHHHHHHHHChhhhhHH-HHHHHHHHHHHhCCCCCC-chHH
Confidence            1 1 1111 234555555554310   0145677778888888765321 111111 1123444444444   23 4566


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..++..
T Consensus       588 ~~~~~~~l~~l~~~  601 (1078)
T 3W3W_A          588 RSYLEQSWSRICRI  601 (1078)
T ss_dssp             HHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH
Confidence            77777777666543


No 301
>5H2V_A Importin subunit beta-3, Ubiquitin-like-specific protease; nuclear import, PROTEIN TRANSPORT-HYDROLASE complex; 2.8A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=90.24  E-value=0.013  Score=64.03  Aligned_cols=158  Identities=9%  Similarity=0.045  Sum_probs=84.1  Template_Neff=13.000

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.++..+....++.++..++.+|..++.....   . .... .-..+++.+...+.+.++.++..++.++..++...
T Consensus       439 ~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~  513 (1078)
T 5H2V_A          439 RILPALISKLTSECTSRVQTHAAAALVNFSEFASK---D-ILEP-YLDSLLTNLLVLLQSNKLYVQEQALTTIAFIAEAA  513 (1078)
T ss_dssp             HHHHHHHHTTSTTSCHHHHHHHHHHHHHHHTTCCH---H-HHGG-GHHHHHHHHHHHTTCSSHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHcccCCCHHHHHHHHHHHHHHHhcCCh---h-hHHH-HHHHHHHHHHHHHhCCCHHHHHHHHHHHHHHHHHh
Confidence            35566666665224567778888888888764221   0 0011 12356666777777677788889999998887652


Q NP_000290.2     627 L-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR---SSASPKAA  701 (747)
Q Consensus       627 e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~---s~~d~eVr  701 (747)
                      . . .... ..+++.+...+....   ..++.++..++.++..++..............+++.+...+.   +. +..++
T Consensus       514 ~~~~~~~~-~~~~~~l~~~l~~~~---~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~-~~~v~  588 (1078)
T 5H2V_A          514 KNKFIKYY-DTLMPLLLNVLKVNN---KDNSVLKGKCMECATLIGFAVGKEKFHEHSQELISILVALQNSDIDE-DDALR  588 (1078)
T ss_dssp             GGGGGGGH-HHHHHHHHHHHTCC-------HHHHHHHHHHHHHHHHHHCHHHHTTTHHHHHHHHHHHHTCC------CHH
T ss_pred             HHHHHHHH-HhHHHHHHHHHHhCC---CCChHHHHHHHHHHHHHHHHHCchhhhHHHHHHHHHHHHHhCCCCCC-chHHH
Confidence            1 1 1111 234555555554310   014567778888888876532111000011123444444444   23 45666


Q NP_000290.2     702 EAARLLLSDMWSS  714 (747)
Q Consensus       702 ~aAL~aLsnL~~~  714 (747)
                      ..++.++..++..
T Consensus       589 ~~~~~~l~~l~~~  601 (1078)
T 5H2V_A          589 SYLEQSWSRICRI  601 (1078)
T ss_dssp             HHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHH
Confidence            7777777666543


No 302
>4NEE_G AP-2 complex subunit sigma, AP-2; clathrin Adaptor AP-2, HIV-1 Nef; 2.8841A {Rattus norvegicus}
Probab=90.08  E-value=0.014  Score=56.75  Aligned_cols=141  Identities=15%  Similarity=0.147  Sum_probs=95.0  Template_Neff=12.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++.++. ++++.++..++.+|..+....+.        .  ...+++.+...+.+.++.++..++.+++.+.....
T Consensus        77 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~al~~l~~~~~~~~  145 (398)
T 4NEE_G           77 GHMEAVNLLS-SNRYTEKQIGYLFISVLVNSNSE--------L--IRLINNAIKNDLASRNPTFMGLALHCIANVGSREM  145 (398)
T ss_dssp             CHHHHHHHHT-CSSHHHHHHHHHHHHHSCCCCHH--------H--HHHHHHHHHHHHHSCCHHHHHHHHHHHHHHCCHHH
T ss_pred             hHHHHHHHHc-CCCccHHHHHHHHHHHHcCCCHH--------H--HHHHHHHHHHHHhCCCHHHHHHHHHHHHhcCCHHH
Confidence            4566777777 46778888888888888764221        1  12356667777777888899999999988764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                           ...+++.+..++  .+      .++.++..++.+|..+....+..   +.....++.+...+.+. ++.++..++
T Consensus       146 -----~~~~~~~l~~~l~~~~------~~~~vr~~a~~~L~~l~~~~~~~---~~~~~~~~~l~~~l~~~-~~~vr~~a~  210 (398)
T 4NEE_G          146 -----AEAFAGEIPKILVAGD------TMDSVKQSAALCLLRLYRTSPDL---VPMGDWTSRVVHLLNDQ-HLGVVTAAT  210 (398)
T ss_dssp             -----HHHHTTHHHHHHHCSS------SCHHHHHHHHHHHHHHHHHCGGG---SCCSSHHHHHHGGGGCS-CHHHHHHHH
T ss_pred             -----HHHHHHhHHHHHhcCC------CCHHHHHHHHHHHHHHHHHChhh---ccccchHHHHHHHhcCC-CHHHHHHHH
Confidence                 112455566666  54      36788999999999987643221   11234567777777665 678888888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..+...
T Consensus       211 ~~l~~l~~~  219 (398)
T 4NEE_G          211 SLITTLAQK  219 (398)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHh
Confidence            888887764


No 303
>6MQ5_A CLIP-associating protein 1; Microtubule Plus End Binding, STRUCTURAL; HET: MSE; 2.146A {Homo sapiens}
Probab=89.98  E-value=0.015  Score=52.93  Aligned_cols=111  Identities=16%  Similarity=0.126  Sum_probs=61.3  Template_Neff=11.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQL----IGLKEKGLPQIA-RLLQSGNSDVVRSGASLLSNM  622 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~----llie~giI~~Ll-~LL~s~d~eVr~~AL~aLsnL  622 (747)
                      .++.++..+. +.++.++..++..|..++.....     ...    ......+++.+. .++.+.++.++..++.++..+
T Consensus         4 ~l~~l~~~l~-~~~~~~r~~a~~~L~~~~~~~~~-----~~~~~~~~~~~~~~~~~l~~~~l~d~~~~vr~~a~~~l~~l   77 (257)
T 6MQ5_A            4 RMESCLAQVL-QKDVGKRLQVGQELIDYFSDKQK-----SADLEHDQTMLDKLVDGLATSWVNSSNYKVVLLGMDILSAL   77 (257)
T ss_dssp             SHHHHHHHHH-CCCHHHHHHHHHHHHHHHHCTTT-----TTTTTTCHHHHHHHHHHCCCCCTTCSSHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHh-cCCHHHHHHHHHHHHHHHhcccc-----ccccccCHHHHHHHHHHHHHHHhcCCcHHHHHHHHHHHHHH
Confidence            3555666676 46778888888888888764321     010    001234555555 456667778888899988888


Q NP_000290.2     623 SRHP-LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       623 a~~~-e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      +... .........+++.++..+.+      .+..++..++.+|..+..
T Consensus        78 ~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~  120 (257)
T 6MQ5_A           78 VTRLQDRFKAQIGTVLPSLIDRLGD------AKDSVREQDQTLLLKIMD  120 (257)
T ss_dssp             HHHHGGGGHHHHHHHHHHHHHHTTC------SCHHHHHHHHHHHHHHHH
T ss_pred             HHHhHHHHHHHHHhHHHHHHHHhcC------CCHHHHHHHHHHHHHHHH
Confidence            7651 11000111244444444443      234455555555555543


No 304
>4UQI_B AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ENDOCYTOSIS, PROTEIN TRANSPORT, LIPID BINDING; HET: IHP; 2.79A {RATTUS NORVEGICUS}
Probab=89.98  E-value=0.015  Score=60.62  Aligned_cols=109  Identities=11%  Similarity=0.011  Sum_probs=67.1  Template_Neff=12.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+....+..........+++.+...+.+.+..++..++.++..+.......   
T Consensus       160 ~~~~~l~~~l~d~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~L~~l~~~~~~~---  236 (657)
T 4UQI_B          160 GFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDRE---  236 (657)
T ss_pred             chHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCChhhhhhhhhcHHHHHHHHhcCCCHHHHHHHHHHHHhhCCCCHHH---
Confidence            34556666666777788888888888887653321111112345566666666666677777888887776432211   


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                        ...+++.+...+. +.++.++..++.++..+..
T Consensus       237 --~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~  268 (657)
T 4UQI_B          237 --AQSICERVTPRLS-HANSAVVLSAVKVLMKFLE  268 (657)
T ss_pred             --HHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHh
Confidence              1234555556665 4566778888888877765


No 305
>4XRI_A Importin Beta; Transport Protein, Nuclear Transport, Transport; HET: GOL, SO4; 2.05A {Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)}
Probab=89.95  E-value=0.014  Score=61.52  Aligned_cols=159  Identities=9%  Similarity=0.055  Sum_probs=88.2  Template_Neff=13.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQS--GNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s--~d~eVr~~AL~aLsnLa~~  625 (747)
                      +++.+...+....+..++..++.++..++.....     ....+ -..+++.+...+.+  .+..++..++.++..++..
T Consensus       651 ~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~~~vr~~a~~~l~~l~~~  724 (882)
T 4XRI_A          651 FAPFLYNALGNQEEPSLCSMAIGLVSDVTRSLGE-----RSQPY-CDNFMNYLLGNLRSTTLANQFKPAILQCFGDIASA  724 (882)
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHhhh-----ccHhh-HHHHHHHHHHHHcCCCCCHHHHHHHHHHHHHHHHh
Confidence            4566666665214566777888888877654221     01111 13466677777766  5677888999999988865


Q NP_000290.2     626 -PLL-HRVMGNQVFPEVTRLLTSHTGN------TSNSEDILSSACYTVRNLMASQPQL-----AKQYFSSSMLNNIINLC  692 (747)
Q Consensus       626 -~e~-~~ll~~giI~~Ll~LL~s~s~~------~~~d~eVr~~Al~aLsnLa~~s~e~-----~~~Lve~giL~~Ll~LL  692 (747)
                       +.. ..++ ..+++.+...+......      ......++..++.++..++......     ...+. ..+++.+...+
T Consensus       725 ~~~~~~~~~-~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~-~~i~~~l~~~~  802 (882)
T 4XRI_A          725 IGGHFETYL-TIVAQVLQQAATITAGPDGSYEMIDYVISLREGIMDAWGGIIGAMKTSNKTNVLQPYV-ESIFALLNSIA  802 (882)
T ss_pred             CCcccHhHH-HHHHHHHHHHhcCCCCCCCCccccccCHHHHHHHHHHHHHHHHhcChhcchhhchhcH-HhHHHHHHHHh
Confidence             211 1111 22444444444321000      0003456667777777776532211     11111 23456666666


Q NP_000290.2     693 RSSAS--PKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       693 ~s~~d--~eVr~aAL~aLsnL~~~~  715 (747)
                      .+. +  ..++..++.++..++...
T Consensus       803 ~~~-~~~~~vr~~a~~~l~~l~~~~  826 (882)
T 4XRI_A          803 NDP-NRSEALMRASMGVIGDLADAY  826 (882)
T ss_pred             cCC-CCCHHHHHHHHHHHHHHHHHh
Confidence            654 4  788889999998887543


No 306
>4NEE_B AP-2 complex subunit sigma, AP-2; clathrin Adaptor AP-2, HIV-1 Nef; 2.8841A {Rattus norvegicus}
Probab=89.83  E-value=0.016  Score=56.57  Aligned_cols=141  Identities=15%  Similarity=0.147  Sum_probs=94.8  Template_Neff=11.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++.++. +++..++..++.+|..+....+.        .  ...+++.+...+.+.++.++..++.+|+.+.....
T Consensus        77 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~al~~l~~~~~~~~  145 (398)
T 4NEE_B           77 GHMEAVNLLS-SNRYTEKQIGYLFISVLVNSNSE--------L--IRLINNAIKNDLASRNPTFMGLALHCIANVGSREM  145 (398)
T ss_pred             hHHHHHHHhc-CCCHHHHHHHHHHHHHhcccCHH--------H--HHHHHHHHHHHhcCCCHHHHHHHHHHHHhhCCHHH
Confidence            4566777776 46778888888888888764221        1  12356667777777888899999999987764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                           ...+++.+..++  .+      .++.++..++.+|..+....+..   +.....++.+...+.+. ++.++..++
T Consensus       146 -----~~~~~~~l~~~l~~~~------~~~~vr~~a~~~L~~l~~~~~~~---~~~~~~~~~l~~~l~~~-~~~vr~~a~  210 (398)
T 4NEE_B          146 -----AEAFAGEIPKILVAGD------TMDSVKQSAALCLLRLYRTSPDL---VPMGDWTSRVVHLLNDQ-HLGVVTAAT  210 (398)
T ss_pred             -----HHHHHHHHHHHHcCCC------CCHHHHHHHHHHHHHHHHHChhH---hcHhhHHHHHHHHhcCC-CHHHHHHHH
Confidence                 112455566666  54      36788999999999987643221   11234567777777665 778888888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..+...
T Consensus       211 ~~l~~l~~~  219 (398)
T 4NEE_B          211 SLITTLAQK  219 (398)
T ss_pred             HHHHHHHHh
Confidence            888887764


No 307
>6EN4_C Splicing factor 3B subunit 3; Protein complex, splicing modulator, SPLICING; HET: BGZ; 3.08A {Homo sapiens}
Probab=89.78  E-value=0.015  Score=61.60  Aligned_cols=153  Identities=8%  Similarity=0.015  Sum_probs=85.9  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .+..+...+. +....++..++.++..+......   ...... ....+++.+...+.+. ..++..++.+|..++....
T Consensus       397 ~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~---~~~~~~-~~~~~~~~l~~~l~~~-~~~~~~a~~~l~~l~~~~~  470 (852)
T 6EN4_C          397 IISRIVDDLK-DEAEQYRKMVMETIEKIMGNLGA---ADIDHK-LEEQLIDGILYAFQEQ-TTEDSVMLNGFGTVVNALG  470 (852)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCCh---hhcCHH-HHHHHHHHHHHhcCCC-HHHHHHHHHHHHHHHHcCC
Confidence            3445555555 34556677777777777653221   000011 1123445555555433 4677888888888876521


Q NP_000290.2     628 -L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 -~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                       . .... ..+++.+...+.+      .++.++..++.++..++..............+++.+...+.+. +..++..++
T Consensus       471 ~~~~~~~-~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~  542 (852)
T 6EN4_C          471 KRVKPYL-PQICGTVLWRLNN------KSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEE-YPEVLGSIL  542 (852)
T ss_pred             hhhHHHH-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhChhhcCHHHHHhHHHHHHHHccCC-CHHHHHHHH
Confidence             1 1111 2345556666655      3678888999999988864322111112223566666666655 667788888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .++..++..
T Consensus       543 ~~l~~l~~~  551 (852)
T 6EN4_C          543 GALKAIVNV  551 (852)
T ss_pred             HHHHHHHHh
Confidence            888777654


No 308
>5A1V_E ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT; TRANSPORT PROTEIN, COPI, COATOMER, COATED; 21.0A {SACCHAROMYCES CEREVISIAE}
Probab=89.57  E-value=0.018  Score=63.83  Aligned_cols=141  Identities=10%  Similarity=0.100  Sum_probs=80.8  Template_Neff=10.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQS-GNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s-~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .++.|+.++.......++..++.++..++...+.          .....+..|...+.+ ..+.++..++++|+.+....
T Consensus       397 ~~~~L~~~L~~~~~~~vr~~a~~~l~~l~~~~~~----------~~~~~l~~L~~~l~~~~~~~~~~~a~~~L~~~~~~~  466 (874)
T 5A1V_E          397 LMNFLFTMLREEGGFEYKRAIVDCIISIIEENSE----------SKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKT  466 (874)
T ss_dssp             HHHHHHHHHHHHSSSSHHHHHHHHHHHHTTTTHH----------HHHHHHHHHHTSCSSSSCHHHHHHHHHHHHHHCCSS
T ss_pred             HHHHHHHHHhhcCCchhHHHHHHHHHHHHHHCHH----------HHHHHHHHHHHHHHhcCCHHHHHHHHHHhcccccCC
Confidence            4555666665222233566677777776653221          112345556666553 34566777777777665431


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ..    ...+++.+...+.+      .++.++..++.+|..+....+.     ....++..|..++.+. +..++..|..
T Consensus       467 ~~----~~~~l~~l~~~l~~------~~~~vr~~al~aL~~l~~~~~~-----~~~~i~~~L~~~l~d~-~~~vR~~A~~  530 (874)
T 5A1V_E          467 NN----PSKYIRFIYNRVVL------EHEEVRAGAVSALAKFGAQNEE-----MLPSILVLLKRCVMDD-DNEVRDRATF  530 (874)
T ss_dssp             SC----HHHHHHHHHHHHHT------SCHHHHHHHHHHHHHHHHHCGG-----GHHHHHHHHHSTTTSS-SSHHHHHHHH
T ss_pred             CC----HHHHHHHHHHhhcc------CCHHHHHHHHHHHHHHHhcCHH-----HHHHHHHHHHHHccCC-CHHHHHHHHH
Confidence            11    01244555555554      3567888888888888764221     1123455555666555 7788888888


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      ++..+...
T Consensus       531 ~l~~l~~~  538 (874)
T 5A1V_E          531 YLNVLEQK  538 (874)
T ss_dssp             HHHHHHTS
T ss_pred             HHHHHHHh
Confidence            88876654


No 309
>5NZR_G Coatomer subunit alpha, Coatomer subunit; COPI, coatomer, coated vesicles, Transport; 9.2A {Mus musculus}
Probab=89.57  E-value=0.018  Score=63.83  Aligned_cols=141  Identities=10%  Similarity=0.100  Sum_probs=80.8  Template_Neff=10.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQS-GNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s-~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .++.|+.++.......++..++.++..++...+.          .....+..|...+.+ ..+.++..++++|+.+....
T Consensus       397 ~~~~L~~~L~~~~~~~vr~~a~~~l~~l~~~~~~----------~~~~~l~~L~~~l~~~~~~~~~~~a~~~L~~~~~~~  466 (874)
T 5NZR_G          397 LMNFLFTMLREEGGFEYKRAIVDCIISIIEENSE----------SKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKT  466 (874)
T ss_pred             HHHHHHHHHhhcCCchhHHHHHHHHHHHHHHCHH----------HHHHHHHHHHHHHHhcCCHHHHHHHHHHhcccccCC
Confidence            4555666665222233566677777776653221          112345556666553 34566777777777665431


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ..    ...+++.+...+.+      .++.++..++.+|..+....+.     ....++..|..++.+. +..++..|..
T Consensus       467 ~~----~~~~l~~l~~~l~~------~~~~vr~~al~aL~~l~~~~~~-----~~~~i~~~L~~~l~d~-~~~vR~~A~~  530 (874)
T 5NZR_G          467 NN----PSKYIRFIYNRVVL------EHEEVRAGAVSALAKFGAQNEE-----MLPSILVLLKRCVMDD-DNEVRDRATF  530 (874)
T ss_pred             CC----HHHHHHHHHHhhcc------CCHHHHHHHHHHHHHHHhcCHH-----HHHHHHHHHHHHccCC-CHHHHHHHHH
Confidence            11    01244555555554      3567888888888888764221     1123455555666555 7788888888


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      ++..+...
T Consensus       531 ~l~~l~~~  538 (874)
T 5NZR_G          531 YLNVLEQK  538 (874)
T ss_pred             HHHHHHHh
Confidence            88876654


No 310
>6OWT_A AP-2 complex subunit alpha, AP-2; AP, HIV, Nef, trafficking, Protein;{Rattus norvegicus}
Probab=89.50  E-value=0.018  Score=64.23  Aligned_cols=98  Identities=19%  Similarity=0.075  Sum_probs=57.2  Template_Neff=11.000

Q NP_000290.2     250 AVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQN  329 (747)
Q Consensus       250 Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~  329 (747)
                      ++.++.+.+...+..+...+..+.......     ...++..+...+.+.++.++..++.++..+....       ....
T Consensus        79 l~~ll~s~~~~~r~~~~~~l~~l~~~~~~~-----~~~ii~~l~~~l~~~~~~vr~~Al~~l~~~~~~~-------~~~~  146 (939)
T 6OWT_A           79 AVNLLSSNRYTEKQIGYLFISVLVNSNSEL-----IRLINNAIKNDLASRNPTFMGLALHCIANVGSRE-------MAEA  146 (939)
T ss_pred             HHHHhcCCCHHHHHHHHHHHHHHccCChHH-----HHHHHHHHHHHhcCCCHHHHHHHHHHHHHhcCHH-------HHHH
Confidence            334455555566666666666655432211     1134455556666667778888888887765321       1123


Q NP_000290.2     330 GIREAVSLL--RRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       330 IL~~Ll~lL--~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ++..+...+  . +.++.++..++.++..+...
T Consensus       147 l~~~l~~~l~~~-~~~~~vR~~a~~~L~~l~~~  178 (939)
T 6OWT_A          147 FAGEIPKILVAG-DTMDSVKQSAALCLLRLYRT  178 (939)
T ss_pred             HHHHHHHHHcCC-CCCHHHHHHHHHHHHHHHHH
Confidence            444555555  4 45677888888888887763


No 311
>5KC2_B Phosphatidylinositol 3-kinase VPS34 (E.C.2.7.1.137), Serine/threonine-protein; autophagy, phosphatidylinositol 3-kinase (PtdIns3K), endocytosis; 28.0A {Saccharomyces cerevisiae}
Probab=89.34  E-value=0.021  Score=68.25  Aligned_cols=151  Identities=13%  Similarity=0.081  Sum_probs=101.4  Template_Neff=9.500

Q NP_000290.2     548 AI-RTYLNLMGKS-KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I-~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ++ +.|+.++. + .+..++..++..|..+....+.       .. ....+++.|...|.+.++.++..++.+|..++..
T Consensus       424 ~~~p~l~~ll~-~~~d~~~R~~al~~L~~~~~~~~~-------~~-~~~~i~p~l~~~l~d~~~~vr~~a~~~l~~l~~~  494 (1454)
T 5KC2_B          424 LFISYLSHSIR-SIVSTATKLKNLELLAVFAQFVSD-------EN-KIDRVVPYFVCCFEDSDQDVQALSLLTLIQVLTS  494 (1454)
T ss_pred             HhHHHHHHHhc-CCCCHHHHHHHHHHHHHHhhhCCH-------HH-HHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHH
Confidence            56 88999998 5 6777888888888887763221       11 2235688888888888999999999999999821


Q NP_000290.2     626 ----PLL-HRVMGNQVFPEVTRLL---TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQY------------------  679 (747)
Q Consensus       626 ----~e~-~~ll~~giI~~Ll~LL---~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~L------------------  679 (747)
                          +.. ...+..++++.|..++   .+      .+..++..|+.+|..|+.........+                  
T Consensus       495 ~~~~~~~~~~~~~~~~l~~L~~ll~~~~d------~~~~vR~~a~~~l~~la~~~~~~~~~~~~~~~~~~~~~~~~~i~~  568 (1454)
T 5KC2_B          495 VRKLNQLNENIFVDYLLPRLKRLLISNRQ------NTNYLRIVFANCLSDLAIIINRFQEFTFAQHCNDNSMDNNTEIME  568 (1454)
T ss_pred             hhcCHHHHHHHHHcCcHHHHHHHHcCCCC------CcHHHHHHHHHHHHHHhcCCCCcceEEhhHHhhhHHHHHHHHHHH
Confidence                111 2234456778888888   65      367888999999998875422111111                  


Q NP_000290.2     680 ----FSSSMLNNIINLCRS----SASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       680 ----ve~giL~~Ll~LL~s----~~d~eVr~aAL~aLsnL~~~  714 (747)
                          ...++++.|..++..    . ++.++..|+.+|..+...
T Consensus       569 ~~~~~~~~~~~~l~~ll~~~l~d~-~~~vr~~a~~~l~~l~~~  610 (1454)
T 5KC2_B          569 SSTKYSAKLIQSVEDLTVSFLTDN-DTYVKMALLQNILPLCKF  610 (1454)
T ss_pred             HHHHHHcCHHHHHHHHHHhhcCCC-CHHHHHHHHHHHHHHhcC
Confidence                123345556555554    4 677777787777777653


No 312
>2P8Q_A Importin beta-1 subunit, Snurportin-1; HEAT repeat, IBB-domain, Importin, Karyopherin; 2.35A {Homo sapiens} SCOP: a.118.1.1
Probab=89.29  E-value=0.018  Score=60.92  Aligned_cols=154  Identities=10%  Similarity=0.087  Sum_probs=87.1  Template_Neff=13.100

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.+|..++.....   . .... ....+++.+...+.+.++.++..++.++..++....
T Consensus       367 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~---~-~~~~-~~~~i~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  440 (876)
T 2P8Q_A          367 VLPFIKEHIK-NPDWRYRDAAVMAFGCILEGPEP---S-QLKP-LVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLP  440 (876)
T ss_dssp             HHHHHHHHTT-CSSHHHHHHHHHHHHHTSSSSCH---H-HHHH-HHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHHHHCG
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhCCCh---h-hcHH-HHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHHHCc
Confidence            3555666666 46677888888888888764221   0 0111 123456677777777778899999999999887521


Q NP_000290.2     628 LH---RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK----------QYFS---SSMLNNIINL  691 (747)
Q Consensus       628 ~~---~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~----------~Lve---~giL~~Ll~L  691 (747)
                      ..   ......+++.+...+.+       ++.++..++.++..++........          ..+.   ..++..+...
T Consensus       441 ~~~~~~~~~~~~~~~l~~~l~~-------~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~  513 (876)
T 2P8Q_A          441 EAAINDVYLAPLLQCLIEGLSA-------EPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLET  513 (876)
T ss_dssp             GGTSSTTTHHHHHHHHHHHTTS-------CHHHHHHHHHHHHHHHHHHHHHHTSSSSSSSCSCCTTGGGHHHHHHHHHHH
T ss_pred             HHhccchhHHHHHHHHHHHccC-------CHHHHHHHHHHHHHHHHHHHHHhccCCCCCCcchhhccHhHHHHHHHHHHH
Confidence            10   11112345555555543       356777888888887754221100          0000   1234444444


Q NP_000290.2     692 CRS--SASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       692 L~s--~~d~eVr~aAL~aLsnL~~~  714 (747)
                      +..  ..+..++..++.++..+...
T Consensus       514 l~~~~~~~~~~r~~~~~~l~~l~~~  538 (876)
T 2P8Q_A          514 TDRPDGHQNNLRSSAYESLMEIVKN  538 (876)
T ss_dssp             TTCTTTTGGGHHHHHHHHHHHHHHS
T ss_pred             hcCCCCCcchHHHHHHHHHHHHHHh
Confidence            431  11456777777777776643


No 313
>2QNA_A Importin subunit beta-1, Snurportin-1; Nuclear transport, import of spliceosomal; HET: SO4; 2.84A {Homo sapiens}
Probab=89.10  E-value=0.019  Score=59.41  Aligned_cols=115  Identities=18%  Similarity=0.151  Sum_probs=67.9  Template_Neff=13.200

Q NP_000290.2     245 LTIPKAVQYLSSQD--EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRS--PNQNVQQAAAGALRNLVFRSTT  320 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd--~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s--~d~eVr~~AL~aLs~La~~~~~  320 (747)
                      .+++.+...+.+.+  ..++..++.++..++...+..........+++.+...+.+  .++.++..++.++..++.....
T Consensus         3 ~l~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~vr~~a~~~l~~l~~~~~~   82 (762)
T 2QNA_A            3 ELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKA   82 (762)
T ss_pred             chHHHHHHHhcCCCCCHHHHHHHHHHHHHHHHhCCHhhcHHHHHhHHHHHHHHhcCCCCCHHHHHHHHHHHHHHHhcCCc
Confidence            34555666666555  6788888888888775432211111112345666666653  3577888888888888754332


Q NP_000290.2     321 NKL-ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       321 ~~~-~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ... ......+++.+...+. +.++.++..++.++..++..
T Consensus        83 ~~~~~~~~~~i~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~  122 (762)
T 2QNA_A           83 NFDKESERHFIMQVVCEATQ-CPDTRVRVAALQNLVKIMSL  122 (762)
T ss_pred             cCCcchhHHhHHHHHHHHhC-CCCHHHHHHHHHHHHHHHHh
Confidence            111 0111234555555665 45677888888888887763


No 314
>1IBR_B RAN  IMPORTIN BETA SUBUNIT; SMALL GTPASE  NUCLEAR TRANSPORT; HET: GNP; 2.3A {Homo sapiens} SCOP: a.118.1.1
Probab=89.10  E-value=0.019  Score=55.65  Aligned_cols=154  Identities=11%  Similarity=0.066  Sum_probs=94.9  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsnLa  623 (747)
                      .++.|...+. +.+  +.++..++.+|..+......   . .... ....+++.+...+.+.+  ..++..++.++..++
T Consensus       129 ~~~~l~~~l~-~~~~~~~~~~~~l~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~~~vr~~a~~~l~~l~  202 (462)
T 1IBR_B          129 LIPQLVANVT-NPNSTEHMKESTLEAIGYICQDIDP---E-QLQD-KSNEILTAIIQGMRKEEPSNNVKLAATNALLNSL  202 (462)
T ss_dssp             HHHHHHHHHH-CTTCCHHHHHHHHHHHHHHHHHSCG---G-GTGG-GHHHHHHHHHHHHSTTCCCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHhh-CCCCchHHHHHHHHHHHHHhhcCCH---H-HHHH-HHHHHHHHHHHHHhCCCCCHHHHHHHHHHHHHHH
Confidence            5666777776 344  67788888888888764221   0 0001 12456777788887766  889999999999887


Q NP_000290.2     624 RHPLL-H--RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       624 ~~~e~-~--~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      ..... .  ......+...+..++.+      .++.++..++.+|..+...............+++.+...+.+. ++.+
T Consensus       203 ~~~~~~~~~~~~~~~~~~~l~~~~~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v  275 (462)
T 1IBR_B          203 EFTKANFDKESERHFIMQVVCEATQC------PDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSD-IDEV  275 (462)
T ss_dssp             TTTHHHHTSHHHHHHHHHHHHHHTTC------SSHHHHHHHHHHHHHHHHHCGGGCTTTTTTTHHHHHHHHHHCS-SHHH
T ss_pred             HHHHHhCCCHHHHHHHHHHHhHHhcC------CCHHHHHHHHHHHHHHHHHHHHHHHHhccHHHHHHHHHHHhcC-CHHH
Confidence            65211 0  11222233334444433      3567888889999888764333222222222366667777665 7788


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..++..
T Consensus       276 ~~~a~~~l~~l~~~  289 (462)
T 1IBR_B          276 ALQGIEFWSNVCDE  289 (462)
T ss_dssp             HHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH
Confidence            88898888888764


No 315
>1QGR_A IMPORTIN BETA SUBUNIT, IMPORTIN ALPHA-2; TRANSPORT RECEPTOR, NUCLEAR IMPORT, HEAT; 2.3A {Homo sapiens} SCOP: a.118.1.1
Probab=88.89  E-value=0.021  Score=60.61  Aligned_cols=154  Identities=10%  Similarity=0.084  Sum_probs=87.2  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.+|..++.....   . .... .-..+++.+...+.+.++.++..++.++..++....
T Consensus       367 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  440 (876)
T 1QGR_A          367 VLPFIKEHIK-NPDWRYRDAAVMAFGCILEGPEP---S-QLKP-LVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLP  440 (876)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHcCCH---H-hcHH-HHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHHhCC
Confidence            3455556666 36677888888888888764221   0 0111 123456677777777788899999999999887521


Q NP_000290.2     628 L--H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK----------QYFS---SSMLNNIINL  691 (747)
Q Consensus       628 ~--~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~----------~Lve---~giL~~Ll~L  691 (747)
                      .  . ......+++.+...+.+       ++.++..++.++..++........          ..+.   ..++..+...
T Consensus       441 ~~~~~~~~~~~~~~~l~~~l~~-------~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~  513 (876)
T 1QGR_A          441 EAAINDVYLAPLLQCLIEGLSA-------EPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLET  513 (876)
T ss_pred             hhhcCCchHHHHHHHHHHHhcC-------CHHHHHHHHHHHHHHHHHhhhccCCCCCCCCCcchhhhhhHHHHHHHHHHH
Confidence            1  0 11112345555555543       356777888888887754221100          0000   1234444444


Q NP_000290.2     692 CRS--SASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       692 L~s--~~d~eVr~aAL~aLsnL~~~  714 (747)
                      +..  ..+..++..++.++..++..
T Consensus       514 l~~~~~~~~~~r~~~~~~l~~l~~~  538 (876)
T 1QGR_A          514 TDRPDGHQNNLRSSAYESLMEIVKN  538 (876)
T ss_pred             hcCCCCCCHHHHHHHHHHHHHHHHc
Confidence            431  11456777788877777643


No 316
>2DB0_A 253aa long hypothetical protein; HEAT repeats, helical structure, Structural; 2.2A {Pyrococcus horikoshii}
Probab=88.88  E-value=0.021  Score=50.55  Aligned_cols=141  Identities=13%  Similarity=0.132  Sum_probs=92.6  Template_Neff=12.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..+......        .  ....++.+...+.+.+..++..++.++..+.....
T Consensus       108 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~~~~~a~~~l~~~~~~~~  176 (253)
T 2DB0_A          108 MIPVLFANYR-IGDEKTKINVSYALEEIAKANPM--------L--MASIVRDFMSMLSSKNREDKLTALNFIEAMGENSF  176 (253)
T ss_dssp             HHHHHHHHSC-CCSHHHHHHHHHHHHHHHHHCHH--------H--HHHHHHHHHHHTSCSSHHHHHHHHHHHHTCCTTTH
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHCHH--------H--HHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHhhcH
Confidence            4566677776 46778888888888887653211        1  13456667777777778888888888887654311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .   .....++.+...+.+      .++.++..++.+|..+....+      .....++.+...+.+. ++.++..++.+
T Consensus       177 ~---~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~~~------~~~~~~~~l~~~l~~~-~~~vr~~a~~~  240 (253)
T 2DB0_A          177 K---YVNPFLPRIINLLHD------GDEIVRASAVEALVHLATLND------KLRKVVIKRLEELNDT-SSLVNKTVKEG  240 (253)
T ss_dssp             H---HHGGGHHHHHGGGGC------SSHHHHHHHHHHHHHHHTSCH------HHHHHHHHHHHHCCCS-CHHHHHHHHHH
T ss_pred             H---hHHhHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCH------HHHHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence            0   011345556666665      367888899999998875322      1123466666667665 67889999999


Q NP_000290.2     708 LSDMWSSK  715 (747)
Q Consensus       708 LsnL~~~~  715 (747)
                      |..+....
T Consensus       241 l~~l~~~~  248 (253)
T 2DB0_A          241 ISRLLLLE  248 (253)
T ss_dssp             HHHHHHC-
T ss_pred             HHHHHHHh
Confidence            98887644


No 317
>2DB0_B 253aa long hypothetical protein; HEAT repeats, helical structure, Structural; 2.2A {Pyrococcus horikoshii}
Probab=88.88  E-value=0.021  Score=50.55  Aligned_cols=141  Identities=13%  Similarity=0.132  Sum_probs=93.1  Template_Neff=12.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..+......        .  ....++.+...+.+.+..++..++.++..+.....
T Consensus       108 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~~~~~a~~~l~~~~~~~~  176 (253)
T 2DB0_B          108 MIPVLFANYR-IGDEKTKINVSYALEEIAKANPM--------L--MASIVRDFMSMLSSKNREDKLTALNFIEAMGENSF  176 (253)
T ss_dssp             HHHHHTTTCC-CCSHHHHHHHHHHHHHHHHHCHH--------H--HHHHHHHHHGGGGCSSHHHHHHHHHHHTTCCTTTH
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHCHH--------H--HHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHhhcH
Confidence            4566677776 46778888888888887653211        1  13456667777777778888888888887654311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .   .....++.+...+.+      .++.++..++.+|..+....+      .....++.+...+.+. ++.++..++.+
T Consensus       177 ~---~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~~~------~~~~~~~~l~~~l~~~-~~~vr~~a~~~  240 (253)
T 2DB0_B          177 K---YVNPFLPRIINLLHD------GDEIVRASAVEALVHLATLND------KLRKVVIKRLEELNDT-SSLVNKTVKEG  240 (253)
T ss_dssp             H---HHGGGHHHHHGGGGC------SCHHHHHHHHHHHHHHHHHCH------HHHHHHHHHHHTCCCS-CHHHHHHHHHH
T ss_pred             H---hHHhHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCH------HHHHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence            0   011345556666665      367888899999998875322      1123466666667665 67889999999


Q NP_000290.2     708 LSDMWSSK  715 (747)
Q Consensus       708 LsnL~~~~  715 (747)
                      |..+....
T Consensus       241 l~~l~~~~  248 (253)
T 2DB0_B          241 ISRLLLLE  248 (253)
T ss_dssp             HHHHHTTC
T ss_pred             HHHHHHHh
Confidence            98887644


No 318
>4K92_B CLIP-associating protein 1; HEAT-Repeat TOG domain, Regulator of; HET: MSE; 2.005A {Homo sapiens}
Probab=88.82  E-value=0.022  Score=52.46  Aligned_cols=148  Identities=16%  Similarity=0.091  Sum_probs=93.3  Template_Neff=11.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.+...+. +.+..++..++.+|..++.....     .... .-..+++.|+..+.+.+..++..++.+|..++....
T Consensus        90 l~~~l~~~l~-d~~~~v~~~a~~~l~~l~~~~~~-----~~~~-~~~~~l~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  162 (273)
T 4K92_B           90 LDGAFKLSAK-DLRSQVVREACITLGHLSSVLGN-----KFDH-GAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTH  162 (273)
T ss_dssp             THHHHHHHHT-CSCHHHHHHHHHHHHHHHHHHGG-----GGHH-HHHHHHHHHHTTTTCSSHHHHHHHHHHHHHHHHHCC
T ss_pred             HHHHHHHHHH-cHHHHHHHHHHHHHHHHHHHHHH-----HhHH-HHHHHHHHHHHHCccccHHHHHHHHHHHHHHHHhCC
Confidence            4556666666 46778888899988888764221     0111 123466677777777777788888888888775421


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .     ..+++.+...+.+      .++.++..++.+|..++...........-..+++.+...+.+. +..++..++.+
T Consensus       163 ~-----~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~i~~~l~~~l~d~-~~~vr~~a~~~  230 (273)
T 4K92_B          163 I-----PRLIPVITSNCTS------KSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDA-DSEARIEARKC  230 (273)
T ss_dssp             C-----TTHHHHHHGGGGC------SCHHHHHHHHHHHHHHHHHSCHHHHTTCHHHHHHHHHHHHTCS-SHHHHHHHHHH
T ss_pred             C-----chHHHHHHHHcCC------CCHHHHHHHHHHHHHHHHHcCchhHHHHHHHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence            1     1234455555554      3577888888888888764322100011123566666777666 78899999999


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      +..+...
T Consensus       231 l~~l~~~  237 (273)
T 4K92_B          231 YWGFHSH  237 (273)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            8887754


No 319
>6MQ7_B CLIP-associating protein 1; microtubule binding protein, STRUCTURAL PROTEIN; 1.78A {Homo sapiens}
Probab=88.82  E-value=0.022  Score=52.46  Aligned_cols=148  Identities=16%  Similarity=0.091  Sum_probs=93.3  Template_Neff=11.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.+...+. +.+..++..++.+|..++.....     .... .-..+++.|+..+.+.+..++..++.+|..++....
T Consensus        90 l~~~l~~~l~-d~~~~v~~~a~~~l~~l~~~~~~-----~~~~-~~~~~l~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  162 (273)
T 6MQ7_B           90 LDGAFKLSAK-DLRSQVVREACITLGHLSSVLGN-----KFDH-GAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTH  162 (273)
T ss_dssp             THHHHHHHHT-CSSHHHHHHHHHHHHHHHHHHGG-----GGHH-HHHHHHHHHHTTTTCSSHHHHHHHHHHHHHHHHHCC
T ss_pred             HHHHHHHHHH-cHHHHHHHHHHHHHHHHHHHHHH-----HhHH-HHHHHHHHHHHHCccccHHHHHHHHHHHHHHHHhCC
Confidence            4556666666 46778888899988888764221     0111 123466677777777777788888888888775421


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .     ..+++.+...+.+      .++.++..++.+|..++...........-..+++.+...+.+. +..++..++.+
T Consensus       163 ~-----~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~i~~~l~~~l~d~-~~~vr~~a~~~  230 (273)
T 6MQ7_B          163 I-----PRLIPVITSNCTS------KSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDA-DSEARIEARKC  230 (273)
T ss_dssp             C-----GGGHHHHHHGGGC------SCHHHHHHHHHHHHHHHHHSCGGGTTTCHHHHHHHHHHHHTCS-SHHHHHHHHHH
T ss_pred             C-----chHHHHHHHHcCC------CCHHHHHHHHHHHHHHHHHcCchhHHHHHHHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence            1     1234455555554      3577888888888888764322100011123566666777666 78899999999


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      +..+...
T Consensus       231 l~~l~~~  237 (273)
T 6MQ7_B          231 YWGFHSH  237 (273)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            8887754


No 320
>1GCJ_B IMPORTIN-BETA; HEAT REPEAT MOTIF, NUCLEAR PORE-TARGETING; HET: MSE; 2.6A {Mus musculus} SCOP: a.118.1.1
Probab=88.73  E-value=0.022  Score=55.37  Aligned_cols=154  Identities=12%  Similarity=0.095  Sum_probs=94.5  Template_Neff=12.800

Q NP_000290.2     548 AIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsnLa  623 (747)
                      .++.|+..+. +.+  +.++..++.+|..+......     .........+++.+...+.+.+  +.++..++.++..+.
T Consensus       135 ~~~~l~~~l~-~~~~~~~~~~~~l~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~vr~~a~~~l~~~~  208 (460)
T 1GCJ_B          135 LIPQLVANVT-NPNSTEHMKESTLEAIGYICQDIDP-----EQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSL  208 (460)
T ss_dssp             HHHHHHHHHH-CTTCCHHHHHHHHHHHHHHHHHSCH-----HHHGGGHHHHHHHHHHHHCTTCSCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHhh-CCCCcHHHHHHHHHHHHHHhhhCCH-----HHhHHHHHHHHHHHHHHHhCCCCCHHHHHHHHHHHHHHH
Confidence            4566777776 344  67788888888888764221     0000112356777777787665  889999999999887


Q NP_000290.2     624 RHPLL--H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       624 ~~~e~--~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      .....  . ......+...+..++.+      .+..++..++.+|..+....+......+...+++.+..++.+. ++.+
T Consensus       209 ~~~~~~~~~~~~~~~~~~~l~~~~~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v  281 (460)
T 1GCJ_B          209 EFTKANFDKESERHFIMQVVCEATQC------PDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSD-IDEV  281 (460)
T ss_dssp             TTCHHHHTSHHHHHHHHHHHHHHTTC------SSHHHHHHHHHHHHHHHTTCGGGGGGTCCCCCHHHHHHHHTCS-SHHH
T ss_pred             HHHHHhCCCHHHHHHHHHHHHHHhCC------CCHHHHHHHHHHHHHHHHHHHHHHHHhccHHHHHHHHHHhhCC-CHHH
Confidence            65111  1 11112233344444443      3567888889999888765333222222222366677777665 7788


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..++..
T Consensus       282 ~~~a~~~l~~l~~~  295 (460)
T 1GCJ_B          282 ALQGIEFWSNVCDE  295 (460)
T ss_dssp             HHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH
Confidence            88899988888764


No 321
>1F59_B IMPORTIN BETA-1/FXFG NUCLEOPORIN; Protein-protein complex, TRANSPORT PROTEIN RECEPTOR; 2.8A {Homo sapiens} SCOP: a.118.1.1
Probab=88.68  E-value=0.022  Score=54.84  Aligned_cols=154  Identities=11%  Similarity=0.067  Sum_probs=94.0  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsnLa  623 (747)
                      .++.+...+. +.+  +.++..++.+|..+......   . .... ....+++.+..++.+.+  ..++..++.++..++
T Consensus       129 ~~~~l~~~l~-~~~~~~~~~~~~l~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~~~vr~~a~~~l~~l~  202 (442)
T 1F59_B          129 LIPQLVANVT-NPNSTEHMKESTLEAIGYICQDIDP---E-QLQD-KSNEILTAIIQGMRKEEPSNNVKLAATNALLNSL  202 (442)
T ss_dssp             HHHHHHHHHH-CTTCCHHHHHHHHHHHHHHHHHSCG---G-GGGG-GHHHHHHHHHHTTSTTCCCHHHHHHHHHHHHHHS
T ss_pred             HHHHHHHHhh-CCCCcHHHHHHHHHHHHHHHhhCCH---H-HhHH-HHHHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHH
Confidence            5666777776 344  67788888888887754221   0 0001 12456777777777766  889999999999987


Q NP_000290.2     624 RHPLL--H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       624 ~~~e~--~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      .....  . ......+...+..++.+      .+..++..++.+|..++...+..........+++.+..++.+. ++.+
T Consensus       203 ~~~~~~~~~~~~~~~~~~~l~~~~~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v  275 (442)
T 1F59_B          203 EFTKANFDKESERHFIMQVVCEATQC------PDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSD-IDEV  275 (442)
T ss_dssp             TTCHHHHHSHHHHHHHHHHHHHHTTC------SSHHHHHHHHHHHHHHHHHTGGGGGGTCCCCCHHHHHHHHHSS-CHHH
T ss_pred             HHHHHcCCCHHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHHHHHHHHhccHHHHHHHHHHhcCC-cHHH
Confidence            65211  1 01112233333333333      3567888889999888765333322222222356666777655 7788


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..++..
T Consensus       276 ~~~a~~~l~~l~~~  289 (442)
T 1F59_B          276 ALQGIEFWSNVCDE  289 (442)
T ss_dssp             HHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhhH
Confidence            88899988888764


No 322
>1UKL_A Importin beta-1 subunit/Sterol regulatory element; Transcription factor, Nuclear transport factor; HET: MSE; 3.0A {Mus musculus} SCOP: a.118.1.1
Probab=88.63  E-value=0.022  Score=60.17  Aligned_cols=113  Identities=10%  Similarity=0.112  Sum_probs=64.3  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTN-KLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~-~~~  324 (747)
                      +++.+...+.+.++.++..++.++..+...............+++.+...+.+.+..++..++.++..++...... ...
T Consensus       367 ~~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~  446 (876)
T 1UKL_A          367 VLPFIKEHIKNPDWRYRDAAVMAFGSILEGPEPNQLKPLVIQAMPTLIELMKDPSVVVRDTTAWTVGRICELLPEAAIND  446 (876)
T ss_dssp             HHHHHHHHSSCSSHHHHHHHHHHHHTTSSSSCHHHHHHHHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHHHHCHHHHSCT
T ss_pred             HHHHHHHHccCCCHHHHHHHHHHHHHHHhCCChhhhHHHHHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHHChHHhcCc
Confidence            3344444455566778888888888876543211111112345566666666667788888888888887543321 001


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      .....+++.+...+. . ++.++..++.++..++..
T Consensus       447 ~~~~~~~~~l~~~l~-~-~~~~~~~~~~~l~~l~~~  480 (876)
T 1UKL_A          447 VYLAPLLQCLIEGLS-A-EPRVASNVCWAFSSLAEA  480 (876)
T ss_dssp             TTHHHHHHHHHHHTT-S-CHHHHHHHHHHHHHHHHH
T ss_pred             cchHHHHHHHHHHhc-C-ChhHHHHHHHHHHHHHHH
Confidence            111234555555554 3 456677777777776653


No 323
>1U6G_C Cullin homolog 1, RING-box protein; cullin repeat, heat repeat, ring; 3.1A {Homo sapiens} SCOP: a.118.1.2
Probab=88.22  E-value=0.025  Score=62.86  Aligned_cols=146  Identities=12%  Similarity=0.093  Sum_probs=89.7  Template_Neff=12.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+. . ++.++..++.++..+....+.   . .... .-..+++.+...+.+.++.++..++.+|+.+.....
T Consensus       891 ~~~~l~~~l~-~-~~~~r~~~~~~l~~i~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  963 (1230)
T 1U6G_C          891 YLPFVLQEIT-S-QPKRQYLLLHSLKEIISSASV---V-GLKP-YVENIWALLLKHCECAEEGTRNVVAECLGKLTLIDP  963 (1230)
T ss_dssp             HHHHHHHHHH-S-CGGGHHHHHHHHHHHHHSSCS---T-TTHH-HHHHHHHHHTTCCCCSSTTHHHHHHHHHHHHHHSSG
T ss_pred             HHHHHHHHHc-c-CchHHHHHHHHHHHHHhcccc---c-ccHH-hHHHHHHHHHHHcCCCChhHHHHHHHHHHHHHccCH
Confidence            4555555554 2 455666777777777653221   0 0001 113466677777777788899999999988876421


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                            ...++.+...+.+      .+..++..++.+|..+....+........ ..++.++..+.+. ++.++..++.+
T Consensus       964 ------~~~~~~l~~~l~~------~~~~~r~~~~~~l~~~~~~~~~~~~~~~~-~~~~~l~~~l~d~-~~~vr~~a~~~ 1029 (1230)
T 1U6G_C          964 ------ETLLPRLKGYLIS------GSSYARSSVVTAVKFTISDHPQPIDPLLK-NCIGDFLKTLEDP-DLNVRRVALVT 1029 (1230)
T ss_dssp             ------GGTHHHHTTTSSS------SCHHHHHHHHHHTGGGCCSSCCTHHHHHH-HHSTTTHHHHSSS-STHHHHHHHHH
T ss_pred             ------HhHHHHHHHHhhC------CCHHHHHHHHHHHHHHHcCCCCCccHHHH-HHHHHHHHHcCCC-CHHHHHHHHHH
Confidence                  1234555666654      25667788888888877643221111222 4567777777766 77888888888


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      +..+...
T Consensus      1030 l~~l~~~ 1036 (1230)
T 1U6G_C         1030 FNSAAHN 1036 (1230)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHhc
Confidence            8888754


No 324
>4MFU_A Beta-catenin-like protein 1; ARM repeats, GENE REGULATION; 2.744A {Homo sapiens}
Probab=88.09  E-value=0.031  Score=59.08  Aligned_cols=135  Identities=14%  Similarity=0.062  Sum_probs=91.1  Template_Neff=8.700

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDE---------SAKQQVYQLGGICKLVDLLRS------PNQNVQQAAAGA  310 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~---------~~~~~li~~~IL~~Ll~lL~s------~d~eVr~~AL~a  310 (747)
                      +++.|+.++.+.+..+...++.+|..++....         .....+...++++.++..+..      .+......++.+
T Consensus        69 ~i~~Lv~LL~~~n~~i~~~a~~~L~~Lt~~~~~~~~~~~~~~~~~~l~~~g~l~~Lv~~L~~~~e~~~~d~~~~~~al~~  148 (490)
T 4MFU_A           69 AVQSLLGLLGHDNTDVSIAVVDLLQELTDIDTLHESEEGAEVLIDALVDGQVVALLVQNLERLDESVKEEADGVHNTLAI  148 (490)
T ss_dssp             HHHHHHHHTSCSSHHHHHHHHHHHHHHHHGGGSSCCCHHHHHHHHHHHHTTHHHHHHHHHHHCCTTCHHHHHHHHHHHHH
T ss_pred             hHHHHHHHhCCCCHHHHHHHHHHHHHHcCcccccCChhhHHHHHHHHHhCCHHHHHHHHHHhccccccchHHHHHHHHHH
Confidence            45566677776667778888888888876432         122333445677777777764      456677888899


Q NP_000290.2     311 LRNLVFRSTTNKLETRRQNGIREAVSLLRRTG--NAEIQKQLTGLLWNLSST-DELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       311 Ls~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~--d~eVr~~AL~aLsnLas~-~~~~~~Lve-giLe~Lv~LL~~  381 (747)
                      |.+++...+.....+...++++.|+..+. ..  ...++..+..+|..++.. ......+.. ++++.|+.+|..
T Consensus       149 L~nL~~~~~~~~~~i~~~~~l~~Ll~~L~-~~~~~~~~k~~a~~~L~~L~~~~~~~~~~l~~~g~i~~Ll~lL~~  222 (490)
T 4MFU_A          149 VENMAEFRPEMCTEGAQQGLLQWLLKRLK-AKMPFDANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQLSV  222 (490)
T ss_dssp             HHHHHHHSTTHHHHHCCCCCHHHHHHHHH-CCSCCCHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHT
T ss_pred             HHHHhccCHHHHHHHHHCCHHHHHHHHHH-cCCCCHHHHHHHHHHHHHHHcCCHHHHHHHHhCchHHHHHHHHHh
Confidence            99888654333333444567888888886 33  467788899999999875 333444444 788888888863


No 325
>6CRI_I Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=87.58  E-value=0.03  Score=55.48  Aligned_cols=141  Identities=14%  Similarity=0.110  Sum_probs=94.1  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+. +.+..++..++.++..+....+.        .  ...+++.+...+.+.++.++..++.++..+.....
T Consensus        37 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  105 (570)
T 6CRI_I           37 LFPDVVNCMQ-TDNLELKKLVYLYLMNYAKSQPD--------M--AIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKI  105 (570)
T ss_dssp             GHHHHHHTCS-CSCHHHHHHHHHHHHHTTTTSTT--------G--GGTTHHHHHHHTSSSCHHHHHHHHHHHHHCCCTTT
T ss_pred             hHHHHHHhcc-CCCHHHHHHHHHHHHHHHccCHh--------H--HHHHHHHHHHHcCCCCHHHHHHHHHHHccCChhHH
Confidence            4555666676 46677888888888887754221        1  12345666777777788889999998888764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                           ...+++.+...+.+      .++.++..++.+|..+....+...   .....++.+...+.+. ++.++..++.+
T Consensus       106 -----~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~~~~~~---~~~~~~~~l~~~l~~~-~~~vr~~a~~~  170 (570)
T 6CRI_I          106 -----TEYLCEPLRKCLKD------EDPYVRKTAAVCVAKLHDINAQLV---EDQGFLDTLKDLISDS-NPMVVANAVAA  170 (570)
T ss_dssp             -----TTTSHHHHHHHHTC------SSHHHHHHHHHHHHHHHHHCHHHH---HHHTHHHHHHHHHTSS-SHHHHHHHHHH
T ss_pred             -----HHHHHHHHHHhcCC------CCHHHHHHHHHHHHHHHHhChhhh---hccchHHHHHHHhcCC-CHHHHHHHHHH
Confidence                 12345556666665      367888999999998876433221   1134567777777766 77888889998


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      |..+...
T Consensus       171 l~~~~~~  177 (570)
T 6CRI_I          171 LSEIAES  177 (570)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHhh
Confidence            8888765


No 326
>3QML_D 78 kDa glucose-regulated protein homolog; Armadillo like repeats, CHAPERONE-PROTEIN TRANSPORT; HET: PO4; 2.31A {Saccharomyces cerevisiae}
Probab=87.49  E-value=0.038  Score=55.35  Aligned_cols=165  Identities=6%  Similarity=-0.069  Sum_probs=100.7  Template_Neff=7.900

Q NP_000290.2     534 ETNPKGSGWLYHSDAIRTYLNLMGKS-KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEK--GLPQIA---RLLQ--  605 (747)
Q Consensus       534 ~~ni~~~~~lve~G~I~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~g--iI~~Ll---~LL~--  605 (747)
                      .+++.....+++.| ++.|+.++... ....++..|+++|+..+.+++.     ....+.+.+  +++.|+   ..|.  
T Consensus        56 ~hdid~a~~~~~~g-~~~L~~~l~~~~~~~~ir~~Aa~iigsa~qNNP~-----aq~~~~~~~~~~l~~Ll~~~~~L~~~  129 (315)
T 3QML_D           56 AHDYKHGYKIITHE-FALLANLSLNENLPLTLRELSTRVITSCLRNNPP-----VVEFINESFPNFKSKIMAALSNLNDS  129 (315)
T ss_dssp             HTSHHHHHHHHHHH-HHHHHHHHHCTTSCHHHHHHHHHHHHHHHTTCTT-----HHHHHHHHCTTHHHHHHHHHHHHHCC
T ss_pred             HccHHHHHHHHHch-HHHHHHHHhCCCCCHHHHHHHHHHHHHHHhhCHH-----HHHHHHHHCccHHHHHHHHHHhhccC
Confidence            34556666677888 88888888721 5678999999999999988764     344445555  677777   4443  


Q NP_000290.2     606 --SGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA------  676 (747)
Q Consensus       606 --s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~------  676 (747)
                        ..++.++..++.+|+.|+.+... ..+    ++..|..++...    ..+..++..++.++..+........      
T Consensus       130 ~~~~~~~v~~k~L~aLS~Lir~~~~~~~F----G~~~L~~~~~~~----~~~~~~~~K~l~ll~dl~~~~~~~~~~~~~~  201 (315)
T 3QML_D          130 NHRSSNILIKRYLSILNELPVTSEDLPIY----STVVLQNVYERN----NKDKQLQIKVLELISKILKADMYENDDTNLI  201 (315)
T ss_dssp             ---CTHHHHHHHHHHHHHSCCCGGGGGGS----CHHHHHHHHHTT----TTCHHHHHHHHHHHHHHHTTTC------CHH
T ss_pred             CCcCCHHHHHHHHHHHHhhcCCCccHhhh----cHHHHHHHHHhC----CCCHHHHHHHHHHHHHHHHhccccCCCcchH
Confidence              35677888999999999987322 222    456666666431    0135677788888888775432211      


Q NP_000290.2     677 --------KQYFSSSMLNNIINLCRSS-ASPKAAEAARLLLSDMW  712 (747)
Q Consensus       677 --------~~Lve~giL~~Ll~LL~s~-~d~eVr~aAL~aLsnL~  712 (747)
                              ......+.+..+...+... .+....+.++.+|..|.
T Consensus       202 ~~~~~~~~~~~~~~~~c~~l~~~L~~~~~d~~~~ek~l~~L~~L~  246 (315)
T 3QML_D          202 LFKRNAENWSSNLQEWANEFQEMVQNKSIDELHTRTFFDTLYNLK  246 (315)
T ss_dssp             HHHHHHHTTCSCCHHHHHHHHHHTTCTTSCHHHHHHHHHHHHHHH
T ss_pred             HhHhhccccchhHHHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHH
Confidence                    1111133445555555421 13455566666666554


No 327
>5IFE_C Splicing factor 3B subunit 5; pre-mRNA splicing, U2 snRNP, essential; 3.1A {Homo sapiens}
Probab=87.43  E-value=0.036  Score=65.15  Aligned_cols=154  Identities=8%  Similarity=0.029  Sum_probs=84.9  Template_Neff=9.800

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .++..++..+. +.+..++..++.+|..++.....  .. .... ....+++.+...+... ...+..++.+|..++...
T Consensus       848 ~il~~l~~~l~-d~~~~~r~~a~~~L~~l~~~~~~--~~-~~~~-~~~~li~~ll~~l~~~-~~~r~~al~~L~~l~~~~  921 (1304)
T 5IFE_C          848 EIISRIVDDLK-DEAEQYRKMVMETIEKIMGNLGA--AD-IDHK-LEEQLIDGILYAFQEQ-TTEDSVMLNGFGTVVNAL  921 (1304)
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhcCh--hh-hHHH-HHHHHHHHHHHHhcCC-HHHHHHHHHHHHHHHHhC
Confidence            34556666666 35556777788888777653211  00 0001 1123444455444432 356677788887777652


Q NP_000290.2     627 L-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       627 e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      . . ..++ ..++..+...+.+      .+..++..++.+|..++..............++..|...+.+. ++.++..+
T Consensus       922 ~~~~~~~l-~~l~~~L~~~L~~------~~~~vR~~A~~~L~~l~~~~~~~~~~~~~~~l~~~L~~~L~d~-~~~vr~~a  993 (1304)
T 5IFE_C          922 GKRVKPYL-PQICGTVLWRLNN------KSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEE-YPEVLGSI  993 (1304)
T ss_pred             HHHhHHHH-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhccCcCHHHHHHHHHHHHHHHhCCC-CHHHHHHH
Confidence            1 1 1111 2355556666655      3678888999999998764222111111123456666666654 56777778


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.+|..++..
T Consensus       994 l~aL~~l~~~ 1003 (1304)
T 5IFE_C          994 LGALKAIVNV 1003 (1304)
T ss_pred             HHHHHHHHHh
Confidence            7777776644


No 328
>6AHD_1 Pre-mRNA-processing-splicing factor 8, Thioredoxin-like protein; Spliceosome, SPLICING; HET: IHP, GTP; 3.8A {Homo sapiens}
Probab=87.43  E-value=0.036  Score=65.15  Aligned_cols=154  Identities=8%  Similarity=0.029  Sum_probs=84.9  Template_Neff=9.800

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .++..++..+. +.+..++..++.+|..++.....  .. .... ....+++.+...+... ...+..++.+|..++...
T Consensus       848 ~il~~l~~~l~-d~~~~~r~~a~~~L~~l~~~~~~--~~-~~~~-~~~~li~~ll~~l~~~-~~~r~~al~~L~~l~~~~  921 (1304)
T 6AHD_1          848 EIISRIVDDLK-DEAEQYRKMVMETIEKIMGNLGA--AD-IDHK-LEEQLIDGILYAFQEQ-TTEDSVMLNGFGTVVNAL  921 (1304)
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhcCh--hh-hHHH-HHHHHHHHHHHHhcCC-HHHHHHHHHHHHHHHHhC
Confidence            34556666666 35556777788888777653211  00 0001 1123444455444432 356677788887777652


Q NP_000290.2     627 L-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       627 e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      . . ..++ ..++..+...+.+      .+..++..++.+|..++..............++..|...+.+. ++.++..+
T Consensus       922 ~~~~~~~l-~~l~~~L~~~L~~------~~~~vR~~A~~~L~~l~~~~~~~~~~~~~~~l~~~L~~~L~d~-~~~vr~~a  993 (1304)
T 6AHD_1          922 GKRVKPYL-PQICGTVLWRLNN------KSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEE-YPEVLGSI  993 (1304)
T ss_pred             HHHhHHHH-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhccCcCHHHHHHHHHHHHHHHhCCC-CHHHHHHH
Confidence            1 1 1111 2355556666655      3678888999999998764222111111123456666666654 56777778


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.+|..++..
T Consensus       994 l~aL~~l~~~ 1003 (1304)
T 6AHD_1          994 LGALKAIVNV 1003 (1304)
T ss_pred             HHHHHHHHHh
Confidence            7777776644


No 329
>5MU7_A Coatomer subunit beta, Coatomer subunit; coatomer, COPI, beta COP, delta; 2.57A {Chaetomium thermophilum var. thermophilum DSM 1495}
Probab=87.43  E-value=0.031  Score=52.40  Aligned_cols=141  Identities=16%  Similarity=0.154  Sum_probs=92.9  Template_Neff=12.800

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL  628 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~  628 (747)
                      ++.++..+. +.++.++..++.+|..+....+.          .....++.+...+.+.+..++..++.+|..+......
T Consensus       190 ~~~l~~~l~-~~~~~~~~~a~~~l~~~~~~~~~----------~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~~  258 (373)
T 5MU7_A          190 LGTVFEGIP-NAEELLQLVEIEFIRKDALHNPQ----------NKPRYLRLIFDLLEANTSTVVYEAASSLTALTNNPVA  258 (373)
T ss_dssp             HHHTGGGGG-GSCHHHHHHHHHHHHHHHHHCGG----------GHHHHHHHHHHHTTCSSHHHHHHHHHHHHHHCCCHHH
T ss_pred             HHHHHhcCC-ChhHHHHHHHHHHHHHHhccCcc----------cHHHHHHHHHHHHhcCCHHHHHHHHHHHHHcCCCHHH
Confidence            455566666 35667777888888887653221          1234566777777777788888888888887743211


Q NP_000290.2     629 HRVMGNQVFPEVTRLLT-SHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       629 ~~ll~~giI~~Ll~LL~-s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                         . ..+++.+...+. +      .++.++..++.+|..+....+..    + ...++.+...+.+. ++.++..++.+
T Consensus       259 ---~-~~~~~~l~~~l~~~------~~~~vr~~a~~~l~~l~~~~~~~----~-~~~~~~l~~~l~~~-~~~vr~~a~~~  322 (373)
T 5MU7_A          259 ---V-KAAAGKFIELAIKE------ADNNVKLIVLDRVDQLRQKNEGI----L-DDLIMEILRVLSSP-DIDVRRKALEI  322 (373)
T ss_dssp             ---H-HHHHHHHHHHHHHC------CCHHHHHHHHHHHHHHHHHTTTT----T-GGGHHHHHHGGGSS-CHHHHHHHHHH
T ss_pred             ---H-HHHHHHHHHHHhhC------CChhHHHHHHHHHHHHHHhCHHH----H-HHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence               1 134556666665 4      36788889999999887643211    1 13566677777665 77889999999


Q NP_000290.2     708 LSDMWSSKE  716 (747)
Q Consensus       708 LsnL~~~~~  716 (747)
                      |..+.....
T Consensus       323 l~~~~~~~~  331 (373)
T 5MU7_A          323 ALEMVSSKN  331 (373)
T ss_dssp             HHTTCCTTT
T ss_pred             HHHHhcCCC
Confidence            998876544


No 330
>5VE8_B Kap123, Histone H3; Bidding yeast karyopherin, 23 HEAT; HET: MSE; 2.7A {Kluyveromyces lactis}
Probab=87.41  E-value=0.031  Score=61.14  Aligned_cols=154  Identities=11%  Similarity=0.104  Sum_probs=81.3  Template_Neff=12.900

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL-QSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL-~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      ++.+...+. ..++.++..++.++..++.....      ... ....+++.++..+ .+.++.++..++.++..++.. +
T Consensus       868 ~~~l~~~~~-~~~~~~r~~~~~~l~~l~~~~~~------~~~-~~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~~~~~  939 (1116)
T 5VE8_B          868 KPVILQLCQ-SKSKNKRSFAVGALSEIALGMRD------ENP-FIQELLEALIISLTNDKSLEVRCNASYGVGLLIEYSS  939 (1116)
T ss_dssp             HHHHHHHTT-CSCHHHHHHHHHHHHHHHHHHGG------GCT-THHHHHHHHHHHHHHCSCHHHHHHHHHHHHHHHHHCC
T ss_pred             HHHHHHHcC-CCCHHHHHHHHHHHHHHHHhCCC------Cch-hHHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHHhCC
Confidence            333444443 24556677777777777653221      111 1134555555553 345678889999999888865 2


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGN----------TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSS  695 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~----------~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~  695 (747)
                      .. ...+ ..+++.|...+......          ......++..++.+|+.+....+...   ....+++.++..+...
T Consensus       940 ~~~~~~~-~~il~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~---~~~~~l~~~~~~l~~~ 1015 (1116)
T 5VE8_B          940 FDVSAIY-SPVLKSLYEILSVADEKNLATEDDEATKEIVDRTFSNVCGCVARMILKHQNLV---PLEHTIPALLSHLPFN 1015 (1116)
T ss_dssp             SCCHHHH-HHHHHHHHHHHHHHHHHC-----CHHHHHHHHHHHHHHHHHHHHHHHHCGGGS---CHHHHHHHHHTTCSCS
T ss_pred             cchhhhH-HHHHHHHHHHhcchhHhccCCCCchhhHHHHHHHHHHHHHHHHHHHHHCcccC---CHHHHHHHHHhcCCCC
Confidence            11 1111 23555566555431000          00245667788888888876533211   1123455555555322


Q NP_000290.2     696 ASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       696 ~d~eVr~aAL~aLsnL~~~  714 (747)
                      .+...+..++.+|..+...
T Consensus      1016 ~~~~~~~~~~~~l~~l~~~ 1034 (1116)
T 5VE8_B         1016 TAFEEYDPIFKLFLKLFQE 1034 (1116)
T ss_dssp             SCGGGHHHHHHHHHHHHHT
T ss_pred             CchhhhHHHHHHHHHHHHh
Confidence            1455666677777766543


No 331
>2IX8_A ELONGATION FACTOR 3A; NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, PHOSPHORYLATION, ELONGATION; 6.0A {SACCHAROMYCES CEREVISIAE}
Probab=87.28  E-value=0.034  Score=61.28  Aligned_cols=150  Identities=9%  Similarity=0.007  Sum_probs=99.4  Template_Neff=11.800

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.|...+. +.++.++..++.+|..+......     .... ....+++.|...+.+.++.++..|+.+|..++...
T Consensus        48 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~  120 (976)
T 2IX8_A           48 HFFGELAKGIK-DKKTAANAMQAVAHIANQSNLSP-----SVEP-YIVQLVPAICTNAGNKDKEIQSVASETLISIVNAV  120 (976)
T ss_dssp             HHHHHHHHHHT-STTTHHHHHHHHHHHSCTTTCCT-----TTHH-HHHTTHHHHHHHTTCSSHHHHHHHHHHHHHHHHHS
T ss_pred             HHHHHHHHHcc-CHHHHHHHHHHHHHHHHHhccCc-----ccHH-HHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHHhc
Confidence            45677777777 46677888888888888753221     0111 12356777777888888889999999999887652


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLL-TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL-~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      ....  ...+++.|...+ .+      .++.++..++.+|..++...+....... ..+++.+..++.+. +..++..++
T Consensus       121 ~~~~--~~~~l~~l~~~l~~~------~~~~vr~~al~~L~~l~~~~~~~~~~~~-~~~~~~l~~~l~d~-~~~vr~~a~  190 (976)
T 2IX8_A          121 NPVA--IKALLPHLTNAIVET------NKWQEKIAILAAFSAMVDAAKDQVALRM-PELIPVLSETMWDT-KKEVKAAAT  190 (976)
T ss_dssp             CGGG--HHHHHHHHHHHHHHC------CCHHHHHHHHHHHHHHHHHSHHHHHHHH-HHHHHHHHHHTTCS-CHHHHHHHH
T ss_pred             CHHH--HHHHHHHHHHHHhhc------CCHHHHHHHHHHHHHHHHHHHHhHHhhc-hhHHHHHHHhhcCC-CHHHHHHHH
Confidence            1111  123556666666 33      3567888899999988864322211111 24677777777766 788899999


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .+|..+..
T Consensus       191 ~~l~~l~~  198 (976)
T 2IX8_A          191 AAMTKATE  198 (976)
T ss_dssp             HHHHHHST
T ss_pred             HHHHHHHH
Confidence            99888876


No 332
>3WOY_A CLIP-associating protein 2; HEAT Repeat, Microtubule binding, Tubulin; 2.1A {Homo sapiens}
Probab=87.26  E-value=0.034  Score=50.12  Aligned_cols=147  Identities=14%  Similarity=0.116  Sum_probs=92.3  Template_Neff=11.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.+..++..++.++..++.....     ....+ -..+++.+...+.+....++..+..++..++....
T Consensus        78 l~~~l~~~l~-d~~~~v~~~a~~~l~~l~~~~~~-----~~~~~-~~~l~~~l~~~l~~~~~~vr~~a~~~l~~i~~~~~  150 (251)
T 3WOY_A           78 LDGALKLSAK-DLRSQVVREACITVAHLSTVLGN-----KFDHG-AEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTH  150 (251)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHHCc-----ccHHH-HHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHcCC
Confidence            4555666666 46678888899999888764321     01111 13456667777766677788888888888875421


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL-AKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~-~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      .     ..+++.+...+.+      .++.++..++.++..++...... .... -..+++.+...+.+. +..++..++.
T Consensus       151 ~-----~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~-~~~i~~~l~~~l~d~-~~~vr~~a~~  217 (251)
T 3WOY_A          151 V-----PRLIPLITSNCTS------KSVPVRRRSFEFLDLLLQEWQTHSLERH-AAVLVETIKKGIHDA-DAEARVEARK  217 (251)
T ss_pred             H-----hhHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHHCHHhhHHh-HHHHHHHHHHHhcCC-CHHHHHHHHH
Confidence            1     1244455555554      35677888888888887542211 1111 123566677777766 7889999999


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      ++..+...
T Consensus       218 ~l~~l~~~  225 (251)
T 3WOY_A          218 TYMGLRNH  225 (251)
T ss_pred             HHHHHHHH
Confidence            88887754


No 333
>5DN7_A Protein FAM179B; TOG domain, STRUCTURAL PROTEIN; 2.2A {Mus musculus}
Probab=87.22  E-value=0.035  Score=51.97  Aligned_cols=146  Identities=10%  Similarity=0.046  Sum_probs=94.2  Template_Neff=11.400

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.+|..++.....     .... .-..+++.|...+.+.+..++..++.+|..+.....
T Consensus        67 l~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~-----~~~~-~~~~l~~~l~~~l~d~~~~vr~~a~~~l~~l~~~~~  139 (293)
T 5DN7_A           67 FISLLYNLLD-DSNFKVVHGTLQVLHLLVIRLGE-----QVQQ-FLGPVIAASVKVLADNKLVIKQEYMKIFLKLMKEVG  139 (293)
T ss_dssp             HHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHHGG-----GGGG-GHHHHHHHHHHGGGCCCHHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHHHH-----HHHH-HHHHHHHHHHHHhcCCcHHHHHHHHHHHHHHHHHHC
Confidence            4555666666 46778888889888888764221     0111 113467777777777778888889998888875311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .     ..+++.+...+.+      .++.++..++.++..+........  ..-..+++.+...+.+. +..++..++.+
T Consensus       140 ~-----~~~~~~l~~~l~~------~~~~vr~~al~~l~~l~~~~~~~~--~~~~~~~~~l~~~l~d~-~~~vr~~a~~~  205 (293)
T 5DN7_A          140 P-----QRVLSLLLENLKH------KHSRVREEVVNICICSLLTYPSED--FDLPKLSFDLAPALVDS-KRRVRQAALEA  205 (293)
T ss_dssp             H-----HHHHHHHHGGGGC------SCHHHHHHHHHHHHHHHHHSCGGG--SCHHHHHHHHGGGGGCS-SHHHHHHHHHH
T ss_pred             H-----HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhCCccc--CCHHHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence            1     1244555555554      367788888888888876432211  11124566677777766 78888889888


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      +..+...
T Consensus       206 l~~l~~~  212 (293)
T 5DN7_A          206 FAVLASS  212 (293)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            8887653


No 334
>4HM9_A Beta-catenin-like protein 1; all alpha-helical, armadillo repeats, PROTEIN; 3.1001A {Homo sapiens}
Probab=87.21  E-value=0.04  Score=59.57  Aligned_cols=135  Identities=14%  Similarity=0.062  Sum_probs=91.1  Template_Neff=8.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDE---------SAKQQVYQLGGICKLVDLLRS------PNQNVQQAAAGA  310 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~---------~~~~~li~~~IL~~Ll~lL~s------~d~eVr~~AL~a  310 (747)
                      .++.|+.++.+.+..+...++.+|..+.....         .....+...++++.|+..+..      .+...+..++.+
T Consensus       147 ~i~~Lv~LL~~~n~di~~~a~~~L~~Lt~~~~~~~~~~~~~~l~~~l~e~g~l~~Lv~~L~~l~e~~~~d~~~~~~al~i  226 (568)
T 4HM9_A          147 AVQSLLGLLGHDNTDVSIAVVDLLQELTDIDTLHESEEGAEVLIDALVDGQVVALLVQNLERLDESVKEEADGVHNTLAI  226 (568)
T ss_dssp             HHHHHHHGGGCSSHHHHHHHHHHHHHHTCHHHHTTCHHHHHHHHHHHHHTTHHHHHHHHHTTCCTTSHHHHHHHHHHHHH
T ss_pred             hHHHHHHHhCCCCHHHHHHHHHHHHHHhCCccccCChhhHHHHHHHHHhCCHHHHHHHHHhcccccccchHHHHHHHHHH
Confidence            45566677776667788888888888875432         112333445677777777765      455677888999


Q NP_000290.2     311 LRNLVFRSTTNKLETRRQNGIREAVSLLRRTG--NAEIQKQLTGLLWNLSST-DELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       311 Ls~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~--d~eVr~~AL~aLsnLas~-~~~~~~Lve-giLe~Lv~LL~~  381 (747)
                      |.+++...+.....+...+++..|+.++. ..  ....+..+..+|..|+.. ......+.. ++++.|+.+|..
T Consensus       227 L~nL~~~~~~~~~~i~~~g~l~~Ll~lL~-~~~~~~~~k~~AaeiL~~L~~~~~~~r~~l~~~g~I~~LL~lL~~  300 (568)
T 4HM9_A          227 VENMAEFRPEMCTEGAQQGLLQWLLKRLK-AKMPFDANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQLSV  300 (568)
T ss_dssp             HHHHHHHCGGGHHHHCCCCCHHHHHHHHH-SSCCCCHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHGG
T ss_pred             HHHHhccCHHHHHHHHHCCHHHHHHHHHH-cCCCCHHHHHHHHHHHHHHHcCCHHHHHHHHhCchHHHHHHHHHh
Confidence            99888653332223344567888888886 33  456788899999999875 344444444 888989988864


No 335
>6S47_Bi 60S ribosomal protein L2-A, 60S; New1, ABCF, Ribosomal Protein, Recycling; HET: ATP; 3.28A {Saccharomyces cerevisiae}
Probab=87.16  E-value=0.035  Score=61.24  Aligned_cols=155  Identities=12%  Similarity=0.055  Sum_probs=101.1  Template_Neff=11.700

Q NP_000290.2     546 SDAIRTYLNLMGKS-KKDATLEACAGALQNLTASK-GLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       546 ~G~I~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s-~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      .++++.|..++. + .++.++..++.+|..++... ..   . ....+. ..+++.|...+.+.++.++..++.+|..++
T Consensus        42 ~~il~~l~~~l~-~~~~~~vr~~a~~~L~~l~~~~~~~---~-~~~~~~-~~~~~~l~~~l~~~~~~vr~~a~~~L~~l~  115 (972)
T 6S47_Bi          42 WKIVDVLSKFIK-PKNPSLVRESAMLIISNIAQFFSGK---P-PQEAYL-LPFFNVALDCISDKENTVKRAAQHAIDSLL  115 (972)
T ss_pred             ccHHHHHHHHcC-CCCCHHHHHHHHHHHHHHHhcCCCh---h-hcHHHH-HHHHHHHHHHhCCCCHHHHHHHHHHHHHHH
Confidence            346777777777 4 56778888999998887643 10   0 001111 236777778888778889999999999887


Q NP_000290.2     624 RHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       624 ~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                      ..... ......+++.|..++.+.     .++.++..++.+|+.++..............+++.|+..+.+. ++.++..
T Consensus       116 ~~~~~-~~~~~~~~~~l~~~l~~~-----~~~~vr~~a~~~l~~i~~~~~~~~~~~~~~~~~~~l~~~l~d~-~~~vr~~  188 (972)
T 6S47_Bi         116 NCFPM-EALTCFVLPTILDYLSSG-----AKWQAKMAALSVVDRIREDSANDLLELTFKDAVPVLTDVATDF-KPELAKQ  188 (972)
T ss_pred             hcCCH-HhhHhchHHHHHHHcCCC-----CCHHHHHHHHHHHHHHHhhCCHHHHHHHHHHHHHHHHHHhcCC-CHHHHHH
Confidence            65111 111113566677776652     1278889999999998554322211112234677777788766 7889999


Q NP_000290.2     704 ARLLLSDMWS  713 (747)
Q Consensus       704 AL~aLsnL~~  713 (747)
                      ++.+|..+..
T Consensus       189 a~~~L~~l~~  198 (972)
T 6S47_Bi         189 GYKTLLDYVS  198 (972)
T ss_pred             HHHHHHHHHH
Confidence            9999988775


No 336
>6QH5_B AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=87.12  E-value=0.034  Score=55.81  Aligned_cols=142  Identities=13%  Similarity=0.105  Sum_probs=94.9  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+. ++++.++..++.+|..+....+.        .  ...+++.+...+.+.++.++..++.+|..+.....
T Consensus        50 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  118 (592)
T 6QH5_B           50 LFPDVVNCMQ-TDNLELKKLVYLYLMNYAKSQPD--------M--AIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKI  118 (592)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCHH--------H--HHHHHHHHHHHccCCCHHHHHHHHHHHHHHcchhh
Confidence            4555666666 46677888888888887654221        1  13456667777778888899999999888765311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                           ...+++.+...+.+      .++.++..++.+|..+....+..   ......++.+...+.+. ++.++..++.+
T Consensus       119 -----~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~---~~~~~~~~~l~~~l~d~-~~~vr~~a~~~  183 (592)
T 6QH5_B          119 -----TEYLCEPLRKCLKD------EDPYVRKTAAVCVAKLHDINAQM---VEDQGFLDSLRDLIADS-NPMVVANAVAA  183 (592)
T ss_pred             -----HHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCchh---hcCccHHHHHHHHhCCC-CHHHHHHHHHH
Confidence                 12345556666655      36788899999999887643221   12234567777777765 77888889888


Q NP_000290.2     708 LSDMWSSK  715 (747)
Q Consensus       708 LsnL~~~~  715 (747)
                      |..+....
T Consensus       184 l~~~~~~~  191 (592)
T 6QH5_B          184 LSEISESH  191 (592)
T ss_pred             HHHHHhcC
Confidence            88887654


No 337
>5A1V_G ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT; TRANSPORT PROTEIN, COPI, COATOMER, COATED; 21.0A {SACCHAROMYCES CEREVISIAE}
Probab=87.07  E-value=0.037  Score=61.89  Aligned_cols=105  Identities=19%  Similarity=0.265  Sum_probs=67.3  Template_Neff=10.900

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL-QSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL-~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ..++.|..++. +.++.++..|+.+|..+.....         .  ....+..++..+ .+.+..++..++.+|..+...
T Consensus       259 ~~~~~L~~~l~-~~~~~vr~~a~~~L~~l~~~~~---------~--~~~~~~~l~~~l~~~~~~~vr~~al~~L~~l~~~  326 (968)
T 5A1V_G          259 RFIRCIYNLLQ-SSSPAVKYEAAGTLVTLSSAPT---------A--IKAAAQCYIDLIIKESDNNVKLIVLDRLVELKEH  326 (968)
T ss_dssp             HHHHHHHHSCC-SSSCSSCCTTHHHHTGGGCSTH---------H--HHHHHHHHHHHHHCCCCCCTTCCCCSCSSSSCSC
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHhCCCHH---------H--HHHHHHHHHHHHHhcCChHHHHHHHHHHHHHhhC
Confidence            35666777777 4667788888888887765311         0  123455566666 566778888999999988753


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      +.....+ ..+++.+...+.+      .+..++..++.+|..+..
T Consensus       327 ~~~~~~~-~~~~~~l~~~l~~------~~~~vr~~al~~L~~l~~  364 (968)
T 5A1V_G          327 PAHERVL-QDLVMDILRVLST------PDLEVRKKTLQLALDLVS  364 (968)
T ss_dssp             CSSCSSC-SHHHHHHTSCSSS------SCHHHHHHHHHHHHHHSS
T ss_pred             cchHHHH-HHHHHHHHHHhCC------CCHHHHHHHHHHHHHHcC
Confidence            2211111 2345556666655      356788888888888765


No 338
>3TJZ_B ADP-ribosylation factor 1, Coatomer subunit; protein trafficking, Golgi membrane, protein; HET: GNP; 2.9A {Saccharomyces cerevisiae}
Probab=86.96  E-value=0.036  Score=52.53  Aligned_cols=16  Identities=25%  Similarity=-0.029  Sum_probs=8.2  Template_Neff=12.100

Q NP_000290.2     697 SPKAAEAARLLLSDMW  712 (747)
Q Consensus       697 d~eVr~aAL~aLsnL~  712 (747)
                      ++.++..++.+|..+.
T Consensus       225 ~~~~~~~~~~~l~~~~  240 (355)
T 3TJZ_B          225 SPFAYCMMIRVASRQL  240 (355)
T ss_pred             CHHHHHHHHHHHHHhC
Confidence            4445555555555544


No 339
>2IW3_B ELONGATION FACTOR 3A; ACETYLATION, ATP-BINDING, ELONGATION FACTOR, PROTEIN; HET: MSE, ADP, SO4; 2.4A {SACCHAROMYCES CEREVISIAE}
Probab=86.93  E-value=0.037  Score=61.15  Aligned_cols=151  Identities=9%  Similarity=0.010  Sum_probs=98.6  Template_Neff=11.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.|+..+. +.++.++..++.++..+......     .... ....+++.+...+.+.++.++..++.+|..++...
T Consensus        54 ~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~d~~~~vr~~a~~~L~~l~~~~  126 (986)
T 2IW3_B           54 HFFGELAKGIK-DKKTAANAMQAVAHIANQSNLSP-----SVEP-YIVQLVPAICTNAGNKDKEIQSVASETLISIVNAV  126 (986)
T ss_dssp             HHHHHHHHHHT-STTTHHHHHHHHHHHSCTTTCCT-----TTHH-HHHTTHHHHHHHTTCSSHHHHHHHHHHHHHHHHHS
T ss_pred             HHHHHHHHhhc-CHHHHHHHHHHHHHHHHhccCCc-----chHH-HHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHHhc
Confidence            35666777776 35566676777777766643221     1111 12356777788888788889999999999887652


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLL-TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL-~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      ....  ...+++.+...+ .+      .++.++..++.+|..++...+....... ..+++.|..++.+. +..++..|+
T Consensus       127 ~~~~--~~~~l~~l~~~l~~~------~~~~vr~~al~~l~~l~~~~~~~~~~~~-~~i~~~l~~~l~d~-~~~vr~~a~  196 (986)
T 2IW3_B          127 NPVA--IKALLPHLTNAIVET------NKWQEKIAILAAFSAMVDAAKDQVALRM-PELIPVLSETMWDT-KKEVKAAAT  196 (986)
T ss_dssp             CGGG--HHHHHHHHHHHHHHC------CCHHHHHHHHHHHHHHHHHSHHHHHHHH-HHHHHHHHHHTTCS-CHHHHHHHH
T ss_pred             CHHH--HHHHHHHHHHHHhhc------CCHHHHHHHHHHHHHHHHHCHHHHHhhH-HHHHHHHHHhcCcC-CHHHHHHHH
Confidence            2111  224566677777 44      3678889999999988865332221111 34677788888766 778999999


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..++..
T Consensus       197 ~~l~~l~~~  205 (986)
T 2IW3_B          197 AAMTKATET  205 (986)
T ss_dssp             HHHHHHGGG
T ss_pred             HHHHHHHHh
Confidence            999888764


No 340
>5NZR_B Coatomer subunit alpha, Coatomer subunit; COPI, coatomer, coated vesicles, Transport; 9.2A {Mus musculus}
Probab=86.79  E-value=0.04  Score=61.63  Aligned_cols=105  Identities=19%  Similarity=0.265  Sum_probs=67.8  Template_Neff=10.900

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL-QSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL-~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ..++.|..++. +.++.++..|+.+|..+.....         .  ....+..++..+ .+.+..++..++.+|..+...
T Consensus       259 ~~~~~L~~~l~-~~~~~vr~~a~~~L~~l~~~~~---------~--~~~~~~~l~~~l~~~~~~~vr~~al~~L~~l~~~  326 (968)
T 5NZR_B          259 RFIRCIYNLLQ-SSSPAVKYEAAGTLVTLSSAPT---------A--IKAAAQCYIDLIIKESDNNVKLIVLDRLVELKEH  326 (968)
T ss_dssp             HHHHHHHHHTS-CCSHHHHHHHHHHHHHHCCCHH---------H--HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHTCC
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHhCCCHH---------H--HHHHHHHHHHHHHhcCChHHHHHHHHHHHHHhhC
Confidence            35667777777 4667788888888887765311         0  123455566666 566788899999999988753


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      ......+ ..+++.+...+.+      .+..++..++.+|..+..
T Consensus       327 ~~~~~~~-~~~~~~l~~~l~~------~~~~vr~~al~~L~~l~~  364 (968)
T 5NZR_B          327 PAHERVL-QDLVMDILRVLST------PDLEVRKKTLQLALDLVS  364 (968)
T ss_dssp             TTCCHHH-HHHHHHHHHGGGS------CCHHHHHHHHHHHHTTCS
T ss_pred             cchHHHH-HHHHHHHHHHhCC------CCHHHHHHHHHHHHHHcC
Confidence            2211111 2345556666655      356788888888888765


No 341
>4P6Z_B BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=86.78  E-value=0.037  Score=55.91  Aligned_cols=142  Identities=14%  Similarity=0.108  Sum_probs=93.4  Template_Neff=12.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+. +.++.++..++.+|..+....+.        .  ...+++.+...+.+.++.++..|+.+|..+.....
T Consensus        66 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  134 (600)
T 4P6Z_B           66 LFPDVVNCMQ-TDNLELKKLVYLYLMNYAKSQPD--------M--AIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKI  134 (600)
T ss_pred             hHHHHHHhcc-CCCHHHHHHHHHHHHHhccCCHh--------H--HHHHHHHHHHHccCCCHHHHHHHHHHHhcCCchHH
Confidence            4455666666 46677888888888877653221        1  12355666667777788888889888888764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                           ...+++.+...+.+      .++.++..++.+|..+....+..   +....+++.+...+.+. ++.++..++.+
T Consensus       135 -----~~~~~~~l~~~l~~------~~~~vr~~a~~~L~~l~~~~~~~---~~~~~~~~~l~~~l~~~-~~~vr~~a~~~  199 (600)
T 4P6Z_B          135 -----TEYLCEPLRKCLKD------EDPYVRKTAAVCVAKLHDINAQL---VEDQGFLDTLKDLISDS-NPMVVANAVAA  199 (600)
T ss_pred             -----HHHHHHHHHHhcCC------CCHHHHHHHHHHHHHHHhhChHH---hhccChHHHHHHHhcCC-CHHHHHHHHHH
Confidence                 12345556666655      36788899999999887643221   11234567777777766 77888999998


Q NP_000290.2     708 LSDMWSSK  715 (747)
Q Consensus       708 LsnL~~~~  715 (747)
                      |..+....
T Consensus       200 l~~l~~~~  207 (600)
T 4P6Z_B          200 LSEIAESH  207 (600)
T ss_pred             HHHHHhhC
Confidence            88887653


No 342
>5VCH_A Kap123; Bidding yeast karyopherin, 23 HEAT; HET: MSE; 2.35A {Kluyveromyces lactis}
Probab=86.69  E-value=0.038  Score=60.48  Aligned_cols=153  Identities=11%  Similarity=0.110  Sum_probs=80.3  Template_Neff=12.900

Q NP_000290.2     550 RTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL-QSGNSDVVRSGASLLSNMSRH-PL  627 (747)
Q Consensus       550 ~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL-~s~d~eVr~~AL~aLsnLa~~-~e  627 (747)
                      +.+...+. +.++.++..++.++..++.....      ... ....+++.++..+ .+.++.++..++.++..+... +.
T Consensus       869 ~~l~~~~~-~~~~~~r~~~~~~l~~l~~~~~~------~~~-~~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~~~~~~  940 (1116)
T 5VCH_A          869 PVILQLCQ-SKSKNKRSFAVGALSEIALGMRD------ENP-FIQELLEALIISLTNDKSLEVRCNASYGVGLLIEYSSF  940 (1116)
T ss_dssp             HHHHHHTT-CSCHHHHHHHHHHHHHHHHHHGG------GCT-THHHHHHHHHHHHHHCSCHHHHHHHHHHHHHHHHHCCS
T ss_pred             HHHHHHcC-CCCHHHHHHHHHHHHHHHHhCCC------Cch-hHHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHHhCCc
Confidence            33444443 24456677777777777653221      111 1134555555553 345678888999999888765 21


Q NP_000290.2     628 L-HRVMGNQVFPEVTRLLTSHTGN----------TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA  696 (747)
Q Consensus       628 ~-~~ll~~giI~~Ll~LL~s~s~~----------~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~  696 (747)
                      . ...+ ..+++.+...+......          ......++..++.+|+.+....+...   .-..+++.++..+....
T Consensus       941 ~~~~~~-~~il~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~---~~~~~l~~~~~~l~~~~ 1016 (1116)
T 5VCH_A          941 DVSAIY-SPVLKSLYEILSVADEKNLATEDDEATKEIVDRTFSNVCGCVARMILKHQNLV---PLEHTIPALLSHLPFNT 1016 (1116)
T ss_dssp             CCHHHH-HHHHHHHHHHHHHHHHHHHSCSSCHHHHHHHHHHHHHHHHHHHHHHHHCGGGS---CHHHHHHHHHTTCSCSS
T ss_pred             chhhhH-HHHHHHHHHHhcchhHhccCCCCchhhHHHHHHHHHHHHHHHHHHHHHCcccC---CHHHHHHHHHhcCCCCC
Confidence            1 1111 23555565555421000          00245667788888888876533211   11234555555553221


Q NP_000290.2     697 SPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       697 d~eVr~aAL~aLsnL~~~  714 (747)
                      +...+..++.+|..+...
T Consensus      1017 ~~~~~~~~~~~l~~l~~~ 1034 (1116)
T 5VCH_A         1017 AFEEYDPIFKLFLKLFQE 1034 (1116)
T ss_dssp             CGGGHHHHHHHHHHHHHT
T ss_pred             chhhhHHHHHHHHHHHHh
Confidence            455666677777666653


No 343
>6BCU_A mTOR, Target of rapamycin complex; PIKK, TRANSFERASE; HET: ATP, GTP; 3.43A {Homo sapiens}
Probab=86.66  E-value=0.04  Score=67.95  Aligned_cols=131  Identities=8%  Similarity=0.114  Sum_probs=72.7  Template_Neff=11.600

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-L  627 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e  627 (747)
                      ++.|...+.+.....++..++.+|..++.....     ....+ -..+++.+...+.+.++.++..++.+|+.++... .
T Consensus       952 ~~~l~~~l~~~~~~~~~~~a~~~l~~i~~~~~~-----~~~~~-l~~l~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~ 1025 (2549)
T 6BCU_A          952 MVALMRIFRDQSLSHHHTMVVQAITFIFKSLGL-----KCVQF-LPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKS 1025 (2549)
T ss_dssp             HHHHHHHCSSTTHHHHHHHHHHHHHHHHHHHTT-----GGGGG-HHHHHHHHHHHHHHSCHHHHHHHHHHHHHHHHHHGG
T ss_pred             HHHHHHHHcCCChHHHHHHHHHHHHHHHHHcCc-----chHHh-HHHHHHHHHHHHhcCCHHHHHHHHHHHHHHHHHHHH
Confidence            555666665222345777888888888764321     11111 2456777778887777788888999998887541 1


Q NP_000290.2     628 L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS  694 (747)
Q Consensus       628 ~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s  694 (747)
                      . ..+. ..+++.+..++..       ...++..++.+|..++........... ..+++.++..+.+
T Consensus      1026 ~~~~~~-~~i~~~l~~~~~~-------~~~v~~~~~~~l~~l~~~~~~~~~~~~-~~l~~~l~~~l~~ 1084 (2549)
T 6BCU_A         1026 HIRPYM-DEIVTLMREFWVM-------NTSIQSTIILLIEQIVVALGGEFKLYL-PQLIPHMLRVFMH 1084 (2549)
T ss_dssp             GGGGGH-HHHHHHHHHTCCS-------CHHHHHHHHHHHHHHHHHHGGGGGGTH-HHHHHHHHHHHHS
T ss_pred             hcHHhH-HHHHHHHHHHHhc-------CHHHHHHHHHHHHHHHHHhcHhhHhHH-HHHHHHHHHHHhc
Confidence            1 1111 2234444444433       244677788888887654222111111 2345555555543


No 344
>6BCX_B mTOR, Target of rapamycin complex; PIKK, TRANSFERASE; HET: ATP; 3.0A {Homo sapiens}
Probab=86.66  E-value=0.04  Score=67.95  Aligned_cols=131  Identities=8%  Similarity=0.114  Sum_probs=72.7  Template_Neff=11.600

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-L  627 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e  627 (747)
                      ++.|...+.+.....++..++.+|..++.....     ....+ -..+++.+...+.+.++.++..++.+|+.++... .
T Consensus       952 ~~~l~~~l~~~~~~~~~~~a~~~l~~i~~~~~~-----~~~~~-l~~l~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~ 1025 (2549)
T 6BCX_B          952 MVALMRIFRDQSLSHHHTMVVQAITFIFKSLGL-----KCVQF-LPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKS 1025 (2549)
T ss_pred             HHHHHHHHcCCChHHHHHHHHHHHHHHHHHcCc-----chHHh-HHHHHHHHHHHHhcCCHHHHHHHHHHHHHHHHHHHH
Confidence            555666665222345777888888888764321     11111 2456777778887777788888999998887541 1


Q NP_000290.2     628 L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS  694 (747)
Q Consensus       628 ~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s  694 (747)
                      . ..+. ..+++.+..++..       ...++..++.+|..++........... ..+++.++..+.+
T Consensus      1026 ~~~~~~-~~i~~~l~~~~~~-------~~~v~~~~~~~l~~l~~~~~~~~~~~~-~~l~~~l~~~l~~ 1084 (2549)
T 6BCX_B         1026 HIRPYM-DEIVTLMREFWVM-------NTSIQSTIILLIEQIVVALGGEFKLYL-PQLIPHMLRVFMH 1084 (2549)
T ss_pred             hcHHhH-HHHHHHHHHHHhc-------CHHHHHHHHHHHHHHHHHhcHhhHhHH-HHHHHHHHHHHhc
Confidence            1 1111 2234444444433       244677788888887654222111111 2345555555543


No 345
>5IFE_C Splicing factor 3B subunit 5; pre-mRNA splicing, U2 snRNP, essential; 3.1A {Homo sapiens}
Probab=86.43  E-value=0.045  Score=64.20  Aligned_cols=110  Identities=15%  Similarity=0.148  Sum_probs=59.4  Template_Neff=9.800

Q NP_000290.2     249 KAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQ  328 (747)
Q Consensus       249 ~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~  328 (747)
                      .+...+.+.+..++..++.+|..++..........+...++..+...+.+.+..++..++.+|..++.............
T Consensus       935 ~L~~~L~~~~~~vR~~A~~~L~~l~~~~~~~~~~~~~~~l~~~L~~~L~d~~~~vr~~al~aL~~l~~~~~~~~l~~~l~ 1014 (1304)
T 5IFE_C          935 TVLWRLNNKSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIK 1014 (1304)
T ss_pred             HHHHHhcCCCHHHHHHHHHHHHHHHHhccCcCHHHHHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhhChHHhcccHH
Confidence            33344445566777778888877765322111111112345556666665566777777777777764432111001112


Q NP_000290.2     329 NGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       329 ~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      .+++.+...+. ..+..++..++.++..++.
T Consensus      1015 ~ll~~L~~~L~-~~~~~Vr~~ai~~L~~i~~ 1044 (1304)
T 5IFE_C         1015 DLLPRLTPILK-NRHEKVQENCIDLVGRIAD 1044 (1304)
T ss_pred             hHHHHHHHHhC-CCCHHHHHHHHHHHHHHHh
Confidence            35555666665 4455667777777776665


No 346
>6AHD_1 Pre-mRNA-processing-splicing factor 8, Thioredoxin-like protein; Spliceosome, SPLICING; HET: IHP, GTP; 3.8A {Homo sapiens}
Probab=86.43  E-value=0.045  Score=64.20  Aligned_cols=110  Identities=15%  Similarity=0.148  Sum_probs=59.4  Template_Neff=9.800

Q NP_000290.2     249 KAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQ  328 (747)
Q Consensus       249 ~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~  328 (747)
                      .+...+.+.+..++..++.+|..++..........+...++..+...+.+.+..++..++.+|..++.............
T Consensus       935 ~L~~~L~~~~~~vR~~A~~~L~~l~~~~~~~~~~~~~~~l~~~L~~~L~d~~~~vr~~al~aL~~l~~~~~~~~l~~~l~ 1014 (1304)
T 6AHD_1          935 TVLWRLNNKSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIK 1014 (1304)
T ss_pred             HHHHHhcCCCHHHHHHHHHHHHHHHHhccCcCHHHHHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhhChHHhcccHH
Confidence            33344445566777778888877765322111111112345556666665566777777777777764432111001112


Q NP_000290.2     329 NGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       329 ~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      .+++.+...+. ..+..++..++.++..++.
T Consensus      1015 ~ll~~L~~~L~-~~~~~Vr~~ai~~L~~i~~ 1044 (1304)
T 6AHD_1         1015 DLLPRLTPILK-NRHEKVQENCIDLVGRIAD 1044 (1304)
T ss_pred             hHHHHHHHHhC-CCCHHHHHHHHHHHHHHHh
Confidence            35555666665 4455667777777776665


No 347
>6LTJ_L Histone H3.2, Histone H4, Histone; Chromatin remodeler, Complex, GENE REGULATION; 3.7A {Xenopus laevis}
Probab=86.40  E-value=0.056  Score=63.52  Aligned_cols=152  Identities=14%  Similarity=0.061  Sum_probs=89.3  Template_Neff=5.100

Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-----NSD----------VVRSGASLLSNMSRHPL  627 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-----d~e----------Vr~~AL~aLsnLa~~~e  627 (747)
                      .+++.++.+|.+|+....-  .. ....+ ...++..|+.++...     ++.          .+..|+.+|+.|+..+.
T Consensus      1065 ~LRenaLviLaNIAg~LdL--s~-~~e~I-~~~ild~LLhwlv~~sa~a~Dp~~~~~~~~~lSp~~lALEaLsKLsv~d~ 1140 (1295)
T 6LTJ_L         1065 MLRENTLVTLANISGQLDL--SP-YPESI-CLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDN 1140 (1295)
T ss_dssp             HHHHHHHHHHHHHGGGCCC--SS-SCHHH-HHHHHHHHHHHHHCCSSSSSSCCTTSCTTCCCCHHHHHHHHHHHHHTSHH
T ss_pred             HHHHHHHHHHHHHHcccCC--CC-CChHh-HHHHHHHHHHHHcCcChhcCChhhccCCCCCCCHHHHHHHHHHHHhCCCc
Confidence            4566788888888764220  00 01111 112455555554321     111          12348899999987643


Q NP_000290.2     628 LH-RVMG-------NQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK-QYFSSSMLNNIINLCRSSA--  696 (747)
Q Consensus       628 ~~-~ll~-------~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~-~Lve~giL~~Ll~LL~s~~--  696 (747)
                      +. .++.       ..++..|+.+|...     .+..+++.++.+|.+|+........ ...+.+.+..|+.+|+...  
T Consensus      1141 N~dlLlat~p~srle~Ll~~LV~lL~~~-----ed~~lrE~AL~lL~~Ls~~~~~~ar~ia~~~g~I~~LV~fLE~~~~~ 1215 (1295)
T 6LTJ_L         1141 NVDLILATPPFSRLEKLYSTMVRFLSDR-----KNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAA 1215 (1295)
T ss_dssp             HHHHHHTSSCHHHHHHHHHHHHHHHHHC-----SSHHHHHHHHHHHHHHHHHCHHHHHHHHTSTTHHHHHHHHHHHHHHH
T ss_pred             hHHHHHhCCCHHHHHHHHHHHHHHhcCC-----CCHHHHHHHHHHHHHHHcCCHHHHHHHHHhcCHHHHHHHHHHHHHHH
Confidence            32 2222       23566677777652     2456788999999999875433322 3334567888888876430  


Q NP_000290.2     697 ---------------------SPKAAEAARLLLSDMWSSKELQGVLRQ  723 (747)
Q Consensus       697 ---------------------d~eVr~aAL~aLsnL~~~~~~~~~~~~  723 (747)
                                           ...+++.|+.+|..|+...+-...+.+
T Consensus      1216 ~~~~~~~~~~~~~~npe~~gtS~~m~rRAA~aL~~La~vp~NR~~F~~ 1263 (1295)
T 6LTJ_L         1216 TQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTL 1263 (1295)
T ss_dssp             HHHCC--------------CCCSHHHHHHHHHHHHHHTTSSSHHHHTT
T ss_pred             HHHHHHHHHHHHhhCCCCCCCCHHHHHHHHHHHHHHhcChhhHHHHHH
Confidence                                 134567788899999887777776665


No 348
>6CRI_R Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=86.18  E-value=0.043  Score=55.49  Aligned_cols=139  Identities=17%  Similarity=0.118  Sum_probs=92.2  Template_Neff=12.500

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .+..++..+. +.+..++..++.+|..+....+.        .  ...+++.+...+.+.++.++..++.+|..+.....
T Consensus        63 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  131 (585)
T 6CRI_R           63 GQLECLKLIA-SQKFTDKRIGYLGAMLLLDERQD--------V--HLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEM  131 (585)
T ss_pred             HHHHHHHHHh-CCCchHHHHHHHHHHHhCCCChH--------H--HHHHHHHHHHHhcCCCHHHHHHHHHHHHhhCCHHH
Confidence            3455666776 46777888888888887754221        1  12345666777777778888888888887764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                           ...+++.+...+.+      .++.++..++.+|..+....+...     ...++.+...+.+. ++.++..++.+
T Consensus       132 -----~~~~~~~l~~~l~~------~~~~vr~~a~~~L~~~~~~~~~~~-----~~~~~~l~~~l~~~-~~~vr~~a~~~  194 (585)
T 6CRI_R          132 -----CRDLAGEVEKLLKT------SNSYLRKKAALCAVHVIRKVPELM-----EMFLPATKNLLNEK-NHGVLHTSVVL  194 (585)
T ss_pred             -----HHHHHHHHHHHHhC------CChHHHHHHHHHHHHHHHHCHHHH-----HHHHHHHHHHHcCC-CHHHHHHHHHH
Confidence                 11345556666665      367888899999998876432221     24566777777665 77888888888


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      |..+...
T Consensus       195 l~~l~~~  201 (585)
T 6CRI_R          195 LTEMCER  201 (585)
T ss_pred             HHHHHHh
Confidence            8887643


No 349
>5DFZ_B Vacuolar protein sorting-associated protein 38; Vps34, Vps15, Vps30, Vps38, Autophagy; 4.4A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=85.86  E-value=0.051  Score=64.44  Aligned_cols=292  Identities=12%  Similarity=0.004  Sum_probs=157.7  Template_Neff=9.900

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQ-AIGAYYIQHTCFQDESA--KQQVYQLGGICKLVDLL---RSPNQNVQQAAAGALRNLVFRS  318 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr-~sAL~aLsnLs~~~~~~--~~~li~~~IL~~Ll~lL---~s~d~eVr~~AL~aLs~La~~~  318 (747)
                      .+++.|+..+.+.+..++ ..++..|..+.......  ........+++.|+.++   .+.++.++..+..+|..+....
T Consensus       464 ~~i~~L~~~l~d~~~~vR~~~a~~~L~~l~~~~~~~~~~~~~~~~~~lp~Li~~L~~~~d~~~~vr~~aa~~l~~~~~~~  543 (1460)
T 5DFZ_B          464 RVVPYFVCCFEDSDQDVQALSLLTLIQVLTSVRKLNQLNENIFVDYLLPRLKRLLISNRQNTNYLRIVFANCLSDLAIII  543 (1460)
T ss_pred             cchHHHHHHhcCCCHHHHHHHHHHHHHHhcCCCCccCCccccCcCChHHHHHHHHHhccCCCHHHHHHHHHHHHHHHHHc
Confidence            455667777777788889 89999998886543211  11223345678888888   7777888888888887774321


Q NP_000290.2     319 TTN------------KLETRRQNGIREAVSL----LRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIP  382 (747)
Q Consensus       319 ~~~------------~~~ll~~~IL~~Ll~l----L~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL~~~  382 (747)
                      ...            .........++.+..+    +. +.++.++..++.+|..+........ ....+++.|+.+|..+
T Consensus       544 ~~~~l~~l~~~~~~~~~~~l~~~~~~~l~~ll~~~l~-d~~~~VR~~A~~aL~~l~~~~~~~~-~~~~~l~~Li~ll~d~  621 (1460)
T 5DFZ_B          544 NRFQEFTFAQHCNDNSSTKYSAKLIQSVEDLTVSFLT-DNDTYVKMALLQNILPLCKFFGRER-TNDIILSHLITYLNDK  621 (1460)
T ss_pred             CHHHHHHHHHhcccChhHHHHcChHHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHhccccccc-cHHhHHHHHHHHhcCC
Confidence            100            0001111223333333    33 4567889999999988876422111 1135666677766321


Q NP_000290.2     383 FSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCV  462 (747)
Q Consensus       383 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  462 (747)
                                      +++|-.+|..+|.+--.      .++               ....+   ..++..|...+.   
T Consensus       622 ----------------~~~VR~~a~~aL~~i~~------~~~---------------~~~~~---~~~i~~L~~~l~---  658 (1460)
T 5DFZ_B          622 ----------------DPALRVSLIQTISGISI------LLG---------------TVTLE---QYILPLLIQTIT---  658 (1460)
T ss_pred             ----------------CHHHHHHHHHHHHHHHh------hcC---------------chhhc---hhHHHHHHHHhc---
Confidence                            35555566666543110      000               00000   011222222111   


Q NP_000290.2     463 AASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGW  542 (747)
Q Consensus       463 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~  542 (747)
                            |..                .+|  |     .+|-.+.      +.+..                 ..+..  . 
T Consensus       659 ------d~~----------------~~v--R-----~~a~~aL------~~~~~-----------------~~~~~--~-  683 (1460)
T 5DFZ_B          659 ------DSE----------------ELV--V-----ISVLQSL------KSLFK-----------------TGLIR--K-  683 (1460)
T ss_pred             ------CCC----------------HHH--H-----HHHHHHH------HHhcC-----------------Ccchh--h-
Confidence                  110                000  0     0111111      00000                 00000  0 


Q NP_000290.2     543 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNM  622 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnL  622 (747)
                      ....++++.|..++. +.++.++..|+.+|..+......      . . ....+++.|+.+|.++++.++..|+.+|..+
T Consensus       684 ~~~~~~i~~l~~~l~-d~~~~VR~~A~~al~~l~~~~~~------~-~-~~~~~l~~L~~~l~d~~~~vr~~a~~aL~~~  754 (1460)
T 5DFZ_B          684 KYYIDISKTTSPLLL-HPNNWIRQFTLMIIIEIINKLSK------A-E-VYCILYPIIRPFFEFDVEFNFKSMISCCKQP  754 (1460)
T ss_pred             cccchhHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHhCC------H-H-HHHHHHHHHHHHhcCCCHHHHHHHHHHhCCC
Confidence            001246778888888 57889999999999988764221      1 1 1246788899999999999999999999998


Q NP_000290.2     623 SRHPLLH----RVMGNQVFPEVTRLLT  645 (747)
Q Consensus       623 a~~~e~~----~ll~~giI~~Ll~LL~  645 (747)
                      .......    ..+..+.+..+..++.
T Consensus       755 ~~~~~~~~~~~~~~~~~~~~~~~~~~~  781 (1460)
T 5DFZ_B          755 VSRSVYNLLCSWSVRASKSLFWKKIIT  781 (1460)
T ss_pred             CCHHHHHHHHHHHHHhchhHHHHHHHH
Confidence            7763331    2244455555555554


No 350
>2QNA_A Importin subunit beta-1, Snurportin-1; Nuclear transport, import of spliceosomal; HET: SO4; 2.84A {Homo sapiens}
Probab=85.76  E-value=0.046  Score=56.33  Aligned_cols=154  Identities=11%  Similarity=0.064  Sum_probs=95.8  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQS--GNSDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s--~d~eVr~~AL~aLsnLa  623 (747)
                      .++.|+..+. +.+  ..++..++.+|..++...+.   . .... ....+++.+...+.+  .++.++..++.+|..++
T Consensus         4 l~~~l~~~l~-~~~~~~~~~~~a~~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~~~vr~~a~~~l~~l~   77 (762)
T 2QNA_A            4 LIPQLVANVT-NPNSTEHMKESTLEAIGYICQDIDP---E-QLQD-KSNEILTAIIQGMRKEEPSNNVKLAATNALLNSL   77 (762)
T ss_pred             hHHHHHHHhc-CCCCCHHHHHHHHHHHHHHHHhCCH---h-hcHH-HHHhHHHHHHHHhcCCCCCHHHHHHHHHHHHHHH
Confidence            4566777776 344  67888899999888764221   0 0111 113456677777764  35788999999999988


Q NP_000290.2     624 RHP-LL-H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       624 ~~~-e~-~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      ... .. . ......+++.+...+.+      .++.++..++.+|..++..............+++.+...+.+. ++.+
T Consensus        78 ~~~~~~~~~~~~~~~i~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~l~~~l~~~~~~~-~~~v  150 (762)
T 2QNA_A           78 EFTKANFDKESERHFIMQVVCEATQC------PDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSD-IDEV  150 (762)
T ss_pred             hcCCccCCcchhHHhHHHHHHHHhCC------CCHHHHHHHHHHHHHHHHhCchhhHHhhHHhHHHHHHHHcCCC-CHHH
Confidence            652 11 1 01122345555566654      3678888999999988764332222222223566666677655 7788


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..+...
T Consensus       151 ~~~a~~~l~~l~~~  164 (762)
T 2QNA_A          151 ALQGIEFWSNVCDE  164 (762)
T ss_pred             HHHHHHHHHHHHhc
Confidence            88888888887754


No 351
>3WOZ_C CLIP-associating protein 2; HEAT Repeat, Microtubule binding, Tubulin; HET: MSE; 2.2A {Mus musculus}
Probab=85.74  E-value=0.049  Score=48.60  Aligned_cols=154  Identities=11%  Similarity=0.036  Sum_probs=91.0  Template_Neff=11.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      ..++.++..+. +.++..|..++..|..++.....   . ....  -..++..+...+.+.+..++..++.++..++.. 
T Consensus         5 ~~~~~~~~~l~-~~~w~~R~~al~~l~~~~~~~~~---~-~~~~--~~~i~~~l~~~l~d~~~~v~~~al~~l~~l~~~~   77 (232)
T 3WOZ_C            5 EDVAEVLNRCA-SSNWSERKEGLLGLQNLLKNQRT---L-SRIE--LKRLCEIFTRMFADPHGKVFSMFLETLVDFIQVH   77 (232)
T ss_dssp             CCHHHHHHHHT-CSSHHHHHHHHHHHHHHHHTTCC---C-CHHH--HHHHHHHHHHHTTCCCHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHh-CCCHHHHHHHHHHHHHHHhcCcc---c-CHHH--HHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHc
Confidence            45666777777 47888899999999888864221   0 0111  135666777777777888999999999988865 


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      ..........+++.++..+.+.     ....++..+..+|..+....+.  ..++ ..+++.+...+.+. ++.++..++
T Consensus        78 ~~~~~~~~~~ll~~ll~~l~d~-----~~~~vr~~a~~~l~~i~~~~~~--~~~~-~~l~~~l~~~~~~~-~~~~r~~~l  148 (232)
T 3WOZ_C           78 KDDLQDWLFVLLTQLLKKMGAD-----LLGSVQAKVQKALDITRESFPN--DLQF-NILMRFTVDQTQTP-SLKVKVAIL  148 (232)
T ss_dssp             GGGCTTTHHHHHHHHHHHTTTT-----CCHHHHHHHHHHHHHHHHHSCH--HHHH-HHHHHHHTCTTCCC-CHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHHHHhccc-----cCHHHHHHHHHHHHHHHHHCCc--chHH-HHHHHHhhccccCC-CHHHHHHHH
Confidence            2111111123555566555441     1456788888888887543211  1111 12233333344433 567777777


Q NP_000290.2     706 LLLSDMWSSKE  716 (747)
Q Consensus       706 ~aLsnL~~~~~  716 (747)
                      .++..++...+
T Consensus       149 ~~l~~l~~~~~  159 (232)
T 3WOZ_C          149 KYIETLAKQMD  159 (232)
T ss_dssp             HHHHHHHTTSC
T ss_pred             HHHHHHHHhcC
Confidence            77777665533


No 352
>3WOZ_D CLIP-associating protein 2; HEAT Repeat, Microtubule binding, Tubulin; HET: MSE; 2.2A {Mus musculus}
Probab=85.74  E-value=0.049  Score=48.60  Aligned_cols=154  Identities=11%  Similarity=0.036  Sum_probs=91.0  Template_Neff=11.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      ..++.++..+. +.++..|..++..|..++.....   . ....  -..++..+...+.+.+..++..++.++..++.. 
T Consensus         5 ~~~~~~~~~l~-~~~w~~R~~al~~l~~~~~~~~~---~-~~~~--~~~i~~~l~~~l~d~~~~v~~~al~~l~~l~~~~   77 (232)
T 3WOZ_D            5 EDVAEVLNRCA-SSNWSERKEGLLGLQNLLKNQRT---L-SRIE--LKRLCEIFTRMFADPHGKVFSMFLETLVDFIQVH   77 (232)
T ss_dssp             CCHHHHHHHHH-CSCHHHHHHHHHHHHHHHHTTCC---C-CHHH--HHHHHHHHHHHTTCCCHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHh-CCCHHHHHHHHHHHHHHHhcCcc---c-CHHH--HHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHc
Confidence            45666777777 47888899999999888864221   0 0111  135666777777777888999999999988865 


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      ..........+++.++..+.+.     ....++..+..+|..+....+.  ..++ ..+++.+...+.+. ++.++..++
T Consensus        78 ~~~~~~~~~~ll~~ll~~l~d~-----~~~~vr~~a~~~l~~i~~~~~~--~~~~-~~l~~~l~~~~~~~-~~~~r~~~l  148 (232)
T 3WOZ_D           78 KDDLQDWLFVLLTQLLKKMGAD-----LLGSVQAKVQKALDITRESFPN--DLQF-NILMRFTVDQTQTP-SLKVKVAIL  148 (232)
T ss_dssp             GGGCGGGHHHHHHHHHHHTTSC-----CCHHHHHHHHHHHHHHHHHSCH--HHHH-HHHHHHHTCSSCCC-CHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHHHHhccc-----cCHHHHHHHHHHHHHHHHHCCc--chHH-HHHHHHhhccccCC-CHHHHHHHH
Confidence            2111111123555566555441     1456788888888887543211  1111 12233333344433 567777777


Q NP_000290.2     706 LLLSDMWSSKE  716 (747)
Q Consensus       706 ~aLsnL~~~~~  716 (747)
                      .++..++...+
T Consensus       149 ~~l~~l~~~~~  159 (232)
T 3WOZ_D          149 KYIETLAKQMD  159 (232)
T ss_dssp             HHHHHHHTTCC
T ss_pred             HHHHHHHHhcC
Confidence            77777665533


No 353
>5DCQ_C artificial repeat proteins (alphaREP3), Fibronectin-binding; adhesin, artificial repeat proteins, complex; HET: FMT; 1.83A {synthetic construct}
Probab=85.49  E-value=0.051  Score=45.36  Aligned_cols=47  Identities=15%  Similarity=0.166  Sum_probs=25.2  Template_Neff=12.100

Q NP_000290.2     654 SEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMW  712 (747)
Q Consensus       654 d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~  712 (747)
                      ++.++..++.+|..+...           ..++.+..++.+. +..++..++.++..+.
T Consensus       120 ~~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~  166 (170)
T 5DCQ_C          120 DSDVRRTAAYALGEIGGE-----------RVRAAMEKLAETG-TGFARKVAVNYLETHK  166 (170)
T ss_dssp             SHHHHHHHHHHHHHHCHH-----------HHHHHHHHHHHHC-CHHHHHHHHHHHHTC-
T ss_pred             CHHHHHHHHHHHHHhchH-----------HHHHHHHHHHHcC-ChHHHHHHHHHHHhcc
Confidence            455666666666555431           1344444555544 5566666766666543


No 354
>4L7M_A Putative uncharacterized protein; HEAT-repeats, Hypothetical, UNKNOWN FUNCTION; HET: MSE, GOL; 2.002A {Thermococcus onnurineus}
Probab=85.26  E-value=0.051  Score=48.13  Aligned_cols=143  Identities=17%  Similarity=0.105  Sum_probs=85.7  Template_Neff=12.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..+...  .          .....++.+..++.+.++.++..++.++..++....
T Consensus       120 ~~~~l~~~l~-~~~~~~~~~a~~~l~~~~~~--~----------~~~~~~~~l~~~l~~~~~~~r~~~~~~l~~l~~~~~  186 (269)
T 4L7M_A          120 AAKTLVSLLE-SPDDMMRIETIDVLSKLQPL--E----------DSKLVRTYINELVVSPDLYTKVAGFCLFLNMLNSSA  186 (269)
T ss_dssp             HHHHHHHHTT-SCCHHHHHHHHHHHTTCCBS--C----------CCHHHHHHHHHHHHCSSHHHHHHHHHHHHHHGGGCS
T ss_pred             HHHHHHHHcC-CCCHHHHHHHHHHHHhcCCh--h----------HhhchHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCC
Confidence            4556666666 35666777777777665321  0          123566777777877778889999999998875311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP-QLAKQYFSSSMLNNIINLCRS--SASPKAAEAA  704 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~-e~~~~Lve~giL~~Ll~LL~s--~~d~eVr~aA  704 (747)
                      ..... ..+++.+...+.+      .++.++..++.+|..+..... .......  +.+..++..+.+  . ++.++..+
T Consensus       187 ~~~~~-~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~~--~~~~~l~~~l~~~~~-~~~vr~~a  256 (269)
T 4L7M_A          187 DSGHL-TLILDEIPSLLQN------DNEFIVELALDVLEKALSFPLLENVKIEL--LKISRIVDGLVYREG-APIIRLKA  256 (269)
T ss_dssp             SCCCG-GGTTTTHHHHHTC------SCHHHHHHHHHHHHHHTTSCCCSCCHHHH--HHHHHHHHHHTTCSS-CHHHHHHH
T ss_pred             CcchH-HHHHHHHHHHHcC------CCHHHHHHHHHHHHHHcCCccHHHHHHHH--HHHHHHHhhccCCCC-CHHHHHHH
Confidence            11111 1245556666665      367888899999988875411 1111111  233344444443  3 67788888


Q NP_000290.2     705 RLLLSDMWS  713 (747)
Q Consensus       705 L~aLsnL~~  713 (747)
                      +.+|..+..
T Consensus       257 ~~~l~~l~~  265 (269)
T 4L7M_A          257 KKVSDLIDS  265 (269)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHH
Confidence            888877653


No 355
>4P6Z_B BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=85.10  E-value=0.053  Score=54.64  Aligned_cols=109  Identities=13%  Similarity=0.033  Sum_probs=65.8  Template_Neff=12.700

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+....+..........+++.+...+.+.+..++..++.++..+.......   
T Consensus       176 ~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~~~~~~~~~---  252 (600)
T 4P6Z_B          176 GFLDTLKDLISDSNPMVVANAVAALSEIAESHPSSNLLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDRE---  252 (600)
T ss_pred             ChHHHHHHHhcCCCHHHHHHHHHHHHHHHhhCCCcchhccCHHHHHHHHHHhhcCCHHHHHHHHHHHHHhCCCCHHH---
Confidence            35566666676777788888888888887643321111112245555666666556667777777777766432211   


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                        ...++..+...+. +.++.++..++.++..+..
T Consensus       253 --~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~  284 (600)
T 4P6Z_B          253 --AQSICERVTPRLS-HANSAVVLSAVKVLMKFME  284 (600)
T ss_pred             --HHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHH
Confidence              1234555555565 4566777788888777765


No 356
>5MU7_A Coatomer subunit beta, Coatomer subunit; coatomer, COPI, beta COP, delta; 2.57A {Chaetomium thermophilum var. thermophilum DSM 1495}
Probab=85.09  E-value=0.053  Score=50.69  Aligned_cols=101  Identities=9%  Similarity=0.074  Sum_probs=54.4  Template_Neff=12.800

Q NP_000290.2     598 PQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK  677 (747)
Q Consensus       598 ~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~  677 (747)
                      +.+...+.+.++.++..++.+|..+......   ....+++.+...+.+      .+..++..++.+|..+... ..   
T Consensus       191 ~~l~~~l~~~~~~~~~~a~~~l~~~~~~~~~---~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~-~~---  257 (373)
T 5MU7_A          191 GTVFEGIPNAEELLQLVEIEFIRKDALHNPQ---NKPRYLRLIFDLLEA------NTSTVVYEAASSLTALTNN-PV---  257 (373)
T ss_dssp             HHTGGGGGGSCHHHHHHHHHHHHHHHHHCGG---GHHHHHHHHHHHTTC------SSHHHHHHHHHHHHHHCCC-HH---
T ss_pred             HHHHhcCCChhHHHHHHHHHHHHHHhccCcc---cHHHHHHHHHHHHhc------CCHHHHHHHHHHHHHcCCC-HH---
Confidence            3344444444444444455444444332100   012344555555544      2556677777777776542 11   


Q NP_000290.2     678 QYFSSSMLNNIINLCR-SSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       678 ~Lve~giL~~Ll~LL~-s~~d~eVr~aAL~aLsnL~~~  714 (747)
                       .. ...++.+...+. +. ++.++..++.+|..+...
T Consensus       258 -~~-~~~~~~l~~~l~~~~-~~~vr~~a~~~l~~l~~~  292 (373)
T 5MU7_A          258 -AV-KAAAGKFIELAIKEA-DNNVKLIVLDRVDQLRQK  292 (373)
T ss_dssp             -HH-HHHHHHHHHHHHHCC-CHHHHHHHHHHHHHHHHH
T ss_pred             -HH-HHHHHHHHHHHhhCC-ChhHHHHHHHHHHHHHHh
Confidence             11 135666777776 44 778888888888888865


No 357
>4UQI_B AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ENDOCYTOSIS, PROTEIN TRANSPORT, LIPID BINDING; HET: IHP; 2.79A {RATTUS NORVEGICUS}
Probab=84.97  E-value=0.056  Score=55.88  Aligned_cols=142  Identities=13%  Similarity=0.105  Sum_probs=95.5  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+. ++++.++..++.++..+....+.        .  ...+++.+...+.+.++.++..++.+++.+.....
T Consensus        50 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  118 (657)
T 4UQI_B           50 LFPDVVNCMQ-TDNLELKKLVYLYLMNYAKSQPD--------M--AIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKI  118 (657)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCHh--------H--HHHHHHHHHHHhcCCCHHHHHHHHHHHhhcCCchh
Confidence            4555666676 46677888888888887764221        1  13456667777777788889999999988864311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                           ...+++.+...+.+      .++.++..++.+|..+....+..   +....+++.+..++.+. ++.++..++.+
T Consensus       119 -----~~~l~~~l~~~l~~------~~~~vr~~a~~~L~~l~~~~~~~---~~~~~~~~~l~~~l~d~-~~~vr~~a~~~  183 (657)
T 4UQI_B          119 -----TEYLCEPLRKCLKD------EDPYVRKTAAVCVAKLHDINAQM---VEDQGFLDSLRDLIADS-NPMVVANAVAA  183 (657)
T ss_pred             -----HHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCHHH---hcCcchHHHHHHHhcCC-CHHHHHHHHHH
Confidence                 12345556666655      36788899999999887643221   12234567777777766 77889999999


Q NP_000290.2     708 LSDMWSSK  715 (747)
Q Consensus       708 LsnL~~~~  715 (747)
                      |..+....
T Consensus       184 l~~l~~~~  191 (657)
T 4UQI_B          184 LSEISESH  191 (657)
T ss_pred             HHHHHhcC
Confidence            88887654


No 358
>6MZE_Z Tubulin alpha-1A chain, Tubulin beta; Microtubule, Tubulin, Tubulin polymerization, Heat; HET: MG, GTP, GDP; 3.6A {Sus scrofa}
Probab=84.94  E-value=0.055  Score=53.37  Aligned_cols=149  Identities=8%  Similarity=0.061  Sum_probs=96.3  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLM-GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       548 ~I~~LL~LL-~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      +++.+...+ . +.++.++..++.++..++.....   . .... ....+++.+...+.+.+..++..++.+|..++...
T Consensus       340 ~~~~l~~~l~~-d~~~~v~~~a~~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~  413 (536)
T 6MZE_Z          340 YLRVLANVIQK-DANVQAVTIAANSVQLLCNSLRS---N-FTRS-YGAIVLVPLLERTKEKKPSVNEAICSALDAVATYC  413 (536)
T ss_dssp             THHHHHHHHHH-CSCHHHHHHHHHHHHHHHHHTTT---C-CSSH-HHHHHHHHHHHHTTCCCHHHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHHhc-CchHHHHHHHHHHHHHHHHHccc---c-ccHH-HHHHHHHHHHHHhhccCHHHHHHHHHHHHHHHHhc
Confidence            556666776 5 46778888999999988764221   0 0101 12356677777777777788888988888887542


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA-------KQYFSSSMLNNIINLCRSSASPK  699 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~-------~~Lve~giL~~Ll~LL~s~~d~e  699 (747)
                      ..     ..+++.+...+.+      .++.++..++.+|..+........       ... ...+++.+...+.+. +..
T Consensus       414 ~~-----~~~~~~l~~~l~~------~~~~vr~~~l~~l~~~~~~~~~~~~~~~~~~~~~-~~~i~~~l~~~l~~~-~~~  480 (536)
T 6MZE_Z          414 GF-----DDCLEETLNYMKH------KTPQVRIECTKFLTRMLQGWKSDGPLQNQLLFKL-LPEVTTAVLKIVNDT-QPT  480 (536)
T ss_dssp             TT-----SSHHHHHHHHHTC------SSHHHHHHHHHHHHHHHHTCCCCSSSCCHHHHTC-CCCCCHHHHHHHTCS-SHH
T ss_pred             CH-----HHHHHHHHHHHcc------CCHHHHHHHHHHHHHHHhcCCCCCchhhHHHHHH-HHHHHHHHHHHHcCC-CHH
Confidence            11     1244555555554      367788889999888876432210       011 123566677777765 778


Q NP_000290.2     700 AAEAARLLLSDMWSSK  715 (747)
Q Consensus       700 Vr~aAL~aLsnL~~~~  715 (747)
                      ++..++.++..+....
T Consensus       481 vr~~a~~~l~~l~~~~  496 (536)
T 6MZE_Z          481 TRNTGFECFATLMKLV  496 (536)
T ss_dssp             HHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHH
Confidence            9999999999888654


No 359
>4MFU_A Beta-catenin-like protein 1; ARM repeats, GENE REGULATION; 2.744A {Homo sapiens}
Probab=84.81  E-value=0.067  Score=56.37  Aligned_cols=117  Identities=12%  Similarity=0.116  Sum_probs=82.7  Template_Neff=8.700

Q NP_000290.2     610 DVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP---------QLAKQY  679 (747)
Q Consensus       610 eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~---------e~~~~L  679 (747)
                      .....++.+|.+|+..+.. ..++..++++.|+.+|.+      .+..+...++.+|.+|+....         .....+
T Consensus        42 ~~L~~ai~~L~~La~~p~~~~~lv~~g~i~~Lv~LL~~------~n~~i~~~a~~~L~~Lt~~~~~~~~~~~~~~~~~~l  115 (490)
T 4MFU_A           42 LDLNDIIQEMHVVATMPDLYHLLVELNAVQSLLGLLGH------DNTDVSIAVVDLLQELTDIDTLHESEEGAEVLIDAL  115 (490)
T ss_dssp             HHHHHHHHHHHTTTTSCCCTHHHHHTTHHHHHHHHTSC------SSHHHHHHHHHHHHHHHHGGGSSCCCHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHhcCHHHHHHHHHCChHHHHHHHhCC------CCHHHHHHHHHHHHHHcCcccccCChhhHHHHHHHH
Confidence            3445678888888876544 455667889999999976      356788899999999987532         235566


Q NP_000290.2     680 FSSSMLNNIINLCRS------SASPKAAEAARLLLSDMWSSK-ELQGVLRQQGFDRNMLGT  733 (747)
Q Consensus       680 ve~giL~~Ll~LL~s------~~d~eVr~aAL~aLsnL~~~~-~~~~~~~~~~~~~~~~~~  733 (747)
                      .+.++++.|+.+|..      . +...+..++.+|.+|+... +....+.+.|+-..++..
T Consensus       116 ~~~g~l~~Lv~~L~~~~e~~~~-d~~~~~~al~~L~nL~~~~~~~~~~i~~~~~l~~Ll~~  175 (490)
T 4MFU_A          116 VDGQVVALLVQNLERLDESVKE-EADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKR  175 (490)
T ss_dssp             HHTTHHHHHHHHHHHCCTTCHH-HHHHHHHHHHHHHHHHHHSTTHHHHHCCCCCHHHHHHH
T ss_pred             HhCCHHHHHHHHHHhccccccc-hHHHHHHHHHHHHHHhccCHHHHHHHHHCCHHHHHHHH
Confidence            677888889888875      3 5677889999999998754 444445555554444433


No 360
>5N3U_B Phycocyanobilin lyase subunit alpha (E.C.4.-.-.-); phycobilisome, chromophorylation, phycocyanin, lyase; 1.89A {Nostoc sp. PCC 7120}
Probab=84.57  E-value=0.06  Score=46.12  Aligned_cols=135  Identities=14%  Similarity=0.143  Sum_probs=82.4  Template_Neff=12.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      +.++.|...+. +.++.++..++.+|..+..                 ..++.+...+.+.++.++..++.+|..+... 
T Consensus        32 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~-----------------~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~-   92 (208)
T 5N3U_B           32 AAIPTLIAVFG-YNNPTAAAIASTALVQLGE-----------------VAVPQLLTQIDDYNYGARAYSIRTLAAIADP-   92 (208)
T ss_dssp             GGHHHHHHHTT-SCCHHHHHHHHHHHHHHGG-----------------GGHHHHHHCCCTTCHHHHHHHHHHHHHHCCG-
T ss_pred             hhHHHHHHHhC-CCCHHHHHHHHHHHHHhCc-----------------chHHHHHHHhhCCCHHHHHHHHHHHHHhcCc-
Confidence            45666777776 3566677777776655432                 1334455666667778888888888776522 


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA-KQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~-~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                              ..++.+...+...     .++.++..++.+|..+........ ........++.+..++.+. ++.++..++
T Consensus        93 --------~~~~~l~~~l~~~-----~~~~vr~~a~~~l~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~vr~~a~  158 (208)
T 5N3U_B           93 --------RALDVLIDAAATD-----FAPSVRRAAAKGLGNLHWHKLEFPDNQTAPKKALETLLFISQDA-EWSIRYAAI  158 (208)
T ss_dssp             --------GGHHHHHHHHHHC-----CCHHHHHHHHHHHTTSCGGGSCTTHHHHHHHHHHHHHHHHTTCS-SHHHHHHHH
T ss_pred             --------chHHHHHHHHccC-----CCHHHHHHHHHHHHhhhccCCCCCCCccCChHHHHHHHHHhcCC-CHHHHHHHH
Confidence                    2344555555431     256788888888888864221111 1111123566666777665 677888888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..+...
T Consensus       159 ~~l~~~~~~  167 (208)
T 5N3U_B          159 VGLQGLVNI  167 (208)
T ss_dssp             HHHHHGGGC
T ss_pred             HHHHHHcCC
Confidence            888887764


No 361
>6QH5_B AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=84.43  E-value=0.06  Score=53.82  Aligned_cols=145  Identities=12%  Similarity=0.031  Sum_probs=94.1  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.+|..+....+.        ......+++.+...+.+.++.++..++.+|..+.....
T Consensus       122 ~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~--------~~~~~~~~~~l~~~l~d~~~~vr~~a~~~l~~~~~~~~  192 (592)
T 6QH5_B          122 LCEPLRKCLK-DEDPYVRKTAAVCVAKLHDINAQ--------MVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHP  192 (592)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCch--------hhcCccHHHHHHHHhCCCCHHHHHHHHHHHHHHHhcCC
Confidence            4566667776 46788889999999988764221        11224677788888888888899999999998886521


Q NP_000290.2     628 --LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 --~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                        ........+++.+...+.+      .++.++..++.+|..+....+..     ....++.+...+.+. ++.++..++
T Consensus       193 ~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~~~~~~~~~-----~~~~~~~l~~~l~~~-~~~vr~~a~  260 (592)
T 6QH5_B          193 NSNLLDLNPQNINKLLTALNE------CTEWGQIFILDCLSNYNPKDDRE-----AQSICERVTPRLSHA-NSAVVLSAV  260 (592)
T ss_pred             hhhhHhHHhhHHHHHHHHhcC------CCHHHHHHHHHHHHHHhcCCHHH-----HHHHHHHHHHHhcCC-CHHHHHHHH
Confidence              1111122355566666654      25677778888888877542221     112455555666655 677888888


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .++..+..
T Consensus       261 ~~l~~l~~  268 (592)
T 6QH5_B          261 KVLMKFLE  268 (592)
T ss_pred             HHHHHHHh
Confidence            88877763


No 362
>2DB0_A 253aa long hypothetical protein; HEAT repeats, helical structure, Structural; 2.2A {Pyrococcus horikoshii}
Probab=84.35  E-value=0.062  Score=47.21  Aligned_cols=104  Identities=10%  Similarity=0.179  Sum_probs=59.0  Template_Neff=12.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~  625 (747)
                      ..++.|+..+. +.++.++..++.+|..+......        .  ...+++.+...+.+. ++.++..++.+|..+...
T Consensus        32 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~~~~~  100 (253)
T 2DB0_A           32 SVLKKLIELLD-DDLWTVVKNAISIIMVIAKTRED--------L--YEPMLKKLFSLLKKSEAIPLTQEIAKAFGQMAKE  100 (253)
T ss_dssp             HHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTTCGG--------G--HHHHHHHHHHHHHHCCSHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHcc-CCCHHHHHHHHHHHHHHHhhCHH--------H--HHHHHHHHHHHHhcCCChhHHHHHHHHHHHHHHh
Confidence            45666777776 46677888888888777643110        0  122445566666666 677888888888777643


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      ...  .+ ...++.+...+.+      .++.++..++.++..+..
T Consensus       101 ~~~--~~-~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~  136 (253)
T 2DB0_A          101 KPE--LV-KSMIPVLFANYRI------GDEKTKINVSYALEEIAK  136 (253)
T ss_dssp             CHH--HH-HHHHHHHHHHSCC------CSHHHHHHHHHHHHHHHH
T ss_pred             CHH--HH-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHH
Confidence            110  00 1133444444444      245556666666665544


No 363
>2DB0_B 253aa long hypothetical protein; HEAT repeats, helical structure, Structural; 2.2A {Pyrococcus horikoshii}
Probab=84.35  E-value=0.062  Score=47.21  Aligned_cols=104  Identities=10%  Similarity=0.179  Sum_probs=59.0  Template_Neff=12.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~  625 (747)
                      ..++.|+..+. +.++.++..++.+|..+......        .  ...+++.+...+.+. ++.++..++.+|..+...
T Consensus        32 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~~~~~  100 (253)
T 2DB0_B           32 SVLKKLIELLD-DDLWTVVKNAISIIMVIAKTRED--------L--YEPMLKKLFSLLKKSEAIPLTQEIAKAFGQMAKE  100 (253)
T ss_dssp             HHHHHHHHHTT-CSSHHHHHHHHHHHHHHGGGCGG--------G--HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHcc-CCCHHHHHHHHHHHHHHHhhCHH--------H--HHHHHHHHHHHHhcCCChhHHHHHHHHHHHHHHh
Confidence            45666777776 46677888888888777643110        0  122445566666666 677888888888777643


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      ...  .+ ...++.+...+.+      .++.++..++.++..+..
T Consensus       101 ~~~--~~-~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~  136 (253)
T 2DB0_B          101 KPE--LV-KSMIPVLFANYRI------GDEKTKINVSYALEEIAK  136 (253)
T ss_dssp             CHH--HH-HHHHHHHTTTCCC------CSHHHHHHHHHHHHHHHH
T ss_pred             CHH--HH-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHH
Confidence            110  00 1133444444444      245556666666665544


No 364
>2JKT_A AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ALTERNATIVE SPLICING, PHOSPHOPROTEIN, PHOSPHORYLATION, PROTEIN; HET: SEP, SO4; 3.4A {MUS MUSCULUS}
Probab=84.21  E-value=0.064  Score=54.84  Aligned_cols=140  Identities=15%  Similarity=0.148  Sum_probs=93.7  Template_Neff=12.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++.++. ++++.++..++.++..+......        .  ...+++.+...+.+.++.++..++.+|..+.....
T Consensus        75 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~al~~l~~~~~~~~  143 (623)
T 2JKT_A           75 GHMEAVNLLS-SNRYTEKQIGYLFISVLVNSNSE--------L--IRLINNAIKNDLASRNPTFMGLALHCIANVGSREM  143 (623)
T ss_dssp             CHHHHHHHTT-CSCHHHHHHHHHHHHHSCCCCHH--------H--HHHHHHHHHHHHHTTCHHHHHHHHHHHHHHCCHHH
T ss_pred             HHHHHHHHHc-CCCccHHHHHHHHHHHhcCCCHH--------H--HHHHHHHHHHHHhCCCHHHHHHHHHHHHhhCCHHH
Confidence            4566777777 46778888888888887653221        1  12355667777777788899999999988764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                           ...+++.+...+  .+      .++.++..++.+|..+....+..   +.....++.+..++.+. ++.++..++
T Consensus       144 -----~~~l~~~l~~~l~~~~------~~~~vr~~a~~~L~~~~~~~~~~---~~~~~~~~~l~~~l~~~-~~~vr~~a~  208 (623)
T 2JKT_A          144 -----AEAFAGEIPKILVAGD------TMDSVKQSAALCLLRLYRTSPDL---VPMGDWTSRVVHLLNDQ-HLGVVTAAT  208 (623)
T ss_dssp             -----HHHHTTHHHHHHHCTT------SCHHHHHHHHHHHHHHHHHCTTT---CCCCTHHHHHHGGGGCS-SHHHHHHHH
T ss_pred             -----HHHHHHhHHHHHHcCC------CCHHHHHHHHHHHHHHHHHChhh---cCccchHHHHHHHhcCC-CHHHHHHHH
Confidence                 112445556666  44      36788999999999887642221   11234567777777766 778888888


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .+|..+..
T Consensus       209 ~~l~~l~~  216 (623)
T 2JKT_A          209 SLITTLAQ  216 (623)
T ss_dssp             HHHHHHHT
T ss_pred             HHHHHHHH
Confidence            88888775


No 365
>3LTJ_A AlphaRep-4; protein engineering, HEAT-like repeat, PROTEIN; 1.8A {synthetic}
Probab=84.11  E-value=0.065  Score=45.71  Aligned_cols=28  Identities=11%  Similarity=0.126  Sum_probs=18.0  Template_Neff=12.300

Q NP_000290.2     685 LNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       685 L~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      ++.+...+.+. +..++..++.++..+..
T Consensus       140 ~~~l~~~l~~~-~~~v~~~a~~~l~~~~~  167 (201)
T 3LTJ_A          140 VEPLIKALKDE-DGWVRQSAADALGEIGG  167 (201)
T ss_dssp             HHHHHHHTTCS-SHHHHHHHHHHHHHHCS
T ss_pred             HHHHHHHHhCC-ChHHHHHHHHHHHHhCc
Confidence            44455555544 56777778888777664


No 366
>4P6Z_B BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=84.10  E-value=0.065  Score=53.98  Aligned_cols=145  Identities=12%  Similarity=0.047  Sum_probs=94.3  Template_Neff=12.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      .++.+...+. +.++.++..++.+|..+....+.        .+....+++.+...+.+.++.++..++.+|..+.... 
T Consensus       138 ~~~~l~~~l~-~~~~~vr~~a~~~L~~l~~~~~~--------~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  208 (600)
T 4P6Z_B          138 LCEPLRKCLK-DEDPYVRKTAAVCVAKLHDINAQ--------LVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESHP  208 (600)
T ss_pred             HHHHHHHhcC-CCCHHHHHHHHHHHHHHHhhChH--------HhhccChHHHHHHHhcCCCHHHHHHHHHHHHHHHhhCC
Confidence            4566677776 46778888999999988764321        1112457778888888888899999999999888652 


Q NP_000290.2     627 L-LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e-~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      . ........+++.+...+.+      .+..++..++.+|..+....+..     ....++.+...+.+. +..++..++
T Consensus       209 ~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~~~~~~~~~-----~~~~~~~l~~~l~~~-~~~vr~~a~  276 (600)
T 4P6Z_B          209 SSNLLDLNPQSINKLLTALNE------CTEWGQIFILDCLANYMPKDDRE-----AQSICERVTPRLSHA-NSAVVLSAV  276 (600)
T ss_pred             CcchhccCHHHHHHHHHHhhc------CCHHHHHHHHHHHHHhCCCCHHH-----HHHHHHHHHHHhcCC-CHHHHHHHH
Confidence            1 1111122355556666654      25677778888888876542221     123455566666655 677788888


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .++..+..
T Consensus       277 ~~l~~l~~  284 (600)
T 4P6Z_B          277 KVLMKFME  284 (600)
T ss_pred             HHHHHHHH
Confidence            88777764


No 367
>6QH7_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: SEP; 3.4A {Rattus norvegicus}
Probab=84.02  E-value=0.067  Score=54.81  Aligned_cols=140  Identities=15%  Similarity=0.148  Sum_probs=93.1  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++.++. ++++.++..++.++..+......        .  ...+++.+...+.+.++.++..++.+|..+.....
T Consensus        75 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~al~~l~~~~~~~~  143 (621)
T 6QH7_A           75 GHMEAVNLLS-SNRYTEKQIGYLFISVLVNSNSE--------L--IRLINNAIKNDLASRNPTFMGLALHCIANVGSREM  143 (621)
T ss_dssp             CHHHHHHHTT-CSSHHHHHHHHHHHHHSCCCCHH--------H--HHHHHHHHHHHHHSCCHHHHHHHHHHHHHHCCHHH
T ss_pred             HHHHHHHHHc-CCCccHHHHHHHHHHHHcCCCHH--------H--HHHHHHHHHHHHhcCCHHHHHHHHHHHHhhCCHHH
Confidence            4556667776 46777888888888887754221        1  12345666677777788899999999988764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                           ...+++.+...+  .+      .++.++..++.+|..+....+..   +.....++.+..++.+. ++.++..++
T Consensus       144 -----~~~l~~~l~~~l~~~~------~~~~vr~~a~~~L~~~~~~~~~~---~~~~~~~~~l~~~l~~~-~~~vr~~a~  208 (621)
T 6QH7_A          144 -----AEAFAGEIPKILVAGD------TMDSVKQSAALCLLRLYRTSPDL---VPMGDWTSRVVHLLNDQ-HLGVVTAAT  208 (621)
T ss_dssp             -----HHHHTTHHHHHHTTSC------CCHHHHHHHHHHHHHHHHHCGGG---CCCCTTHHHHHHGGGCS-SHHHHHHHH
T ss_pred             -----HHHHHhhHHHHHHcCC------CCHHHHHHHHHHHHHHHHHChhh---cCccchHHHHHHHhcCC-CHHHHHHHH
Confidence                 112445556666  44      36788999999999887643221   11234567777777765 778888888


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .+|..+..
T Consensus       209 ~~l~~l~~  216 (621)
T 6QH7_A          209 SLITTLAQ  216 (621)
T ss_dssp             HHHHHHHT
T ss_pred             HHHHHHHH
Confidence            88888775


No 368
>6CRI_R Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=83.93  E-value=0.067  Score=53.93  Aligned_cols=67  Identities=18%  Similarity=0.165  Sum_probs=49.2  Template_Neff=12.500

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      +++.+...+. +.++.++..++.+|..+....+.        .  ...+++.|...+.+.++.++..++.+|..+...
T Consensus       135 ~~~~l~~~l~-~~~~~vr~~a~~~L~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  201 (585)
T 6CRI_R          135 LAGEVEKLLK-TSNSYLRKKAALCAVHVIRKVPE--------L--MEMFLPATKNLLNEKNHGVLHTSVVLLTEMCER  201 (585)
T ss_pred             HHHHHHHHHh-CCChHHHHHHHHHHHHHHHHCHH--------H--HHHHHHHHHHHHcCCCHHHHHHHHHHHHHHHHh
Confidence            4566777777 46778888999999888764221        1  135677788888878888999999999888754


No 369
>4UQI_B AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ENDOCYTOSIS, PROTEIN TRANSPORT, LIPID BINDING; HET: IHP; 2.79A {RATTUS NORVEGICUS}
Probab=83.87  E-value=0.069  Score=55.16  Aligned_cols=145  Identities=12%  Similarity=0.031  Sum_probs=94.3  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.+|..+....+.        .+....+++.+..++.+.++.++..++.+|..+.....
T Consensus       122 l~~~l~~~l~-~~~~~vr~~a~~~L~~l~~~~~~--------~~~~~~~~~~l~~~l~d~~~~vr~~a~~~l~~l~~~~~  192 (657)
T 4UQI_B          122 LCEPLRKCLK-DEDPYVRKTAAVCVAKLHDINAQ--------MVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHP  192 (657)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCHH--------HhcCcchHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCC
Confidence            4566667776 46778888999999988764321        11224677788888888888899999999999887521


Q NP_000290.2     628 --LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 --~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                        ........+++.+...+.+      .++.++..++.+|..+.......     ...+++.+...+.+. +..++..++
T Consensus       193 ~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~L~~l~~~~~~~-----~~~~~~~l~~~l~~~-~~~vr~~a~  260 (657)
T 4UQI_B          193 NSNLLDLNPQNINKLLTALNE------CTEWGQIFILDCLSNYNPKDDRE-----AQSICERVTPRLSHA-NSAVVLSAV  260 (657)
T ss_pred             hhhhhhhhhcHHHHHHHHhcC------CCHHHHHHHHHHHHhhCCCCHHH-----HHHHHHHHHHHhcCC-CHHHHHHHH
Confidence              1111123355666666655      35677888888888887542221     112455566666555 667777777


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .++..+..
T Consensus       261 ~~l~~l~~  268 (657)
T 4UQI_B          261 KVLMKFLE  268 (657)
T ss_pred             HHHHHHHh
Confidence            77777663


No 370
>5XAH_A Importin-4; Histone, Chromatin, Assembly, PROTEIN TRANSPORT; HET: MSE; 3.004A {Homo sapiens}
Probab=83.55  E-value=0.071  Score=50.49  Aligned_cols=142  Identities=14%  Similarity=0.108  Sum_probs=83.6  Template_Neff=12.900

Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRHP-LLHRVMGNQVFP  638 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~~-e~~~ll~~giI~  638 (747)
                      ++.++..++.++..++.....   . ....+ -..+++.+...+.+. +..++..++.++..++... .........+++
T Consensus       163 ~~~v~~~a~~~l~~l~~~~~~---~-~~~~~-~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~  237 (416)
T 5XAH_A          163 DAMLLEHAGEAIPALAAAAGG---D-SFAPF-FAGFLPLLVCKTKQGCTVAEKSFAVGTLAETIQGLGAASAQFVSRLLP  237 (416)
T ss_dssp             HHHHHHHHHHHHHHHHHHHTS---T-TTHHH-HHHHHHHHHHTTSSSSCHHHHHHHHHHHHHHHHHHGGGGGGGHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHhCc---c-chHHH-HHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHH
Confidence            455667778888777654210   0 01111 133556666666543 3567778888888877541 111111123566


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR-SSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~-s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      .+...+.+      .++.++..++.+|..++...+......+ ..+++.+...+. +. ++.++..++.++..++...
T Consensus       238 ~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~-~~i~~~l~~~l~~~~-~~~v~~~a~~~l~~l~~~~  307 (416)
T 5XAH_A          238 VLLSTAQE------ADPEVRSNAIFGMGVLAEHGGHPAQEHF-PKLLGLLFPLLARER-HDRVRDNICGALARLLMAS  307 (416)
T ss_dssp             HHHHHTSC------SSHHHHHHHHHHHHHHHHHHHHHHHTTH-HHHHHHHTTHHHHCC-CHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHhhc------CCHHHHHHHHHHHHHHHHhcCchHHhhH-HHHHHHHHHHhccCC-CHHHHHHHHHHHHHHHHhC
Confidence            66666655      3678889999999998865332222222 235666777776 44 6778888888888877543


No 371
>5XAH_C Importin-4; Histone, Chromatin, Assembly, PROTEIN TRANSPORT; HET: MSE; 3.004A {Homo sapiens}
Probab=83.55  E-value=0.071  Score=50.49  Aligned_cols=142  Identities=14%  Similarity=0.108  Sum_probs=83.6  Template_Neff=12.900

Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRHP-LLHRVMGNQVFP  638 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~~-e~~~ll~~giI~  638 (747)
                      ++.++..++.++..++.....   . ....+ -..+++.+...+.+. +..++..++.++..++... .........+++
T Consensus       163 ~~~v~~~a~~~l~~l~~~~~~---~-~~~~~-~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~  237 (416)
T 5XAH_C          163 DAMLLEHAGEAIPALAAAAGG---D-SFAPF-FAGFLPLLVCKTKQGCTVAEKSFAVGTLAETIQGLGAASAQFVSRLLP  237 (416)
T ss_dssp             HHHHHHHHHTHHHHHHHHHTS---T-TTHHH-HHHHHHHHHHTTSTTSCHHHHHHHHHHHHHHHHHHGGGGGGGHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHhCc---c-chHHH-HHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHH
Confidence            455667778888777654210   0 01111 133556666666543 3567778888888877541 111111123566


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR-SSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~-s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      .+...+.+      .++.++..++.+|..++...+......+ ..+++.+...+. +. ++.++..++.++..++...
T Consensus       238 ~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~-~~i~~~l~~~l~~~~-~~~v~~~a~~~l~~l~~~~  307 (416)
T 5XAH_C          238 VLLSTAQE------ADPEVRSNAIFGMGVLAEHGGHPAQEHF-PKLLGLLFPLLARER-HDRVRDNICGALARLLMAS  307 (416)
T ss_dssp             HHHHHTTC------SSHHHHHHHHHHHHHHHHHSHHHHHTTH-HHHHHHHTHHHHHCC-CHHHHHHHHHHHHHHHHTS
T ss_pred             HHHHHhhc------CCHHHHHHHHHHHHHHHHhcCchHHhhH-HHHHHHHHHHhccCC-CHHHHHHHHHHHHHHHHhC
Confidence            66666655      3678889999999998865332222222 235666777776 44 6778888888888877543


No 372
>5FRS_A SISTER CHROMATID COHESION PROTEIN PDS5; COHESIN, DNA REPLICATION, SISTER CHROMATID; 4.073A {SACCHAROMYCES CEREVISIAE}
Probab=83.54  E-value=0.08  Score=57.55  Aligned_cols=149  Identities=7%  Similarity=0.080  Sum_probs=99.5  Template_Neff=9.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      +++.|...+. +.++.++..|+.+|..+....+.   . .... ....+++.++..+.+.++.++..++.++..+... +
T Consensus       282 vl~~L~~~l~-~~~~~vR~~A~~~L~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~d~~~~vR~~a~~~l~~~~~~~~  355 (703)
T 5FRS_A          282 VIGFIYHELS-SENELFRKEATKLIGQILTSYSD---L-NFVS-THSDTFKAWISKIADISPDVRVEWTESIPQIIATRE  355 (703)
T ss_pred             hHHHHHHHhc-CCCHHHHHHHHHHHHHHhCCCCc---c-cHHH-HchhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHhCH
Confidence            5666666676 46778899999999988764221   0 0011 1245667777777778889999999999988764 2


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ..    ...+++.+...+.+      .++.++..|+.+|+.+.....  .........++.+...+.+. +..++..|+.
T Consensus       356 ~~----~~~i~~~l~~~l~D------~d~~VR~~A~~~L~~~~~~~~--~~~~~~~~~l~~l~~~l~d~-~~~VR~~A~~  422 (703)
T 5FRS_A          356 DI----SKELNQALAKTFID------SDPRVRRTSVMIFNKVPVTEI--WKNITNKAIYTSLLHLAREK-HKEVRELCIN  422 (703)
T ss_pred             HH----HHHHHHHHHHHhcC------CCHHHHHHHHHHHHhhcccCc--cccCCCcccHHHHHHHhcCC-CHHHHHHHHH
Confidence            11    22356666666666      478999999999998865321  00111234567777777766 7789999999


Q NP_000290.2     707 LLSDMWSSK  715 (747)
Q Consensus       707 aLsnL~~~~  715 (747)
                      +|..+....
T Consensus       423 ~L~~l~~~~  431 (703)
T 5FRS_A          423 TMAKFYSNS  431 (703)
T ss_pred             HHHHHHHhC
Confidence            888777543


No 373
>4HM9_A Beta-catenin-like protein 1; all alpha-helical, armadillo repeats, PROTEIN; 3.1001A {Homo sapiens}
Probab=83.50  E-value=0.087  Score=56.79  Aligned_cols=136  Identities=13%  Similarity=0.067  Sum_probs=87.4  Template_Neff=8.100

Q NP_000290.2     246 TIPKAVQYLSS------QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP--NQNVQQAAAGALRNLVFR  317 (747)
Q Consensus       246 iL~~Ll~lL~s------sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~--d~eVr~~AL~aLs~La~~  317 (747)
                      +++.|+..+..      .+...+..++.+|.+++...+.....+...++++.|+.++...  ....+..+..+|..++..
T Consensus       198 ~l~~Lv~~L~~l~e~~~~d~~~~~~al~iL~nL~~~~~~~~~~i~~~g~l~~Ll~lL~~~~~~~~~k~~AaeiL~~L~~~  277 (568)
T 4HM9_A          198 VVALLVQNLERLDESVKEEADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILLQD  277 (568)
T ss_dssp             HHHHHHHHHTTCCTTSHHHHHHHHHHHHHHHHHHHHCGGGHHHHCCCCCHHHHHHHHHSSCCCCHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHHhcccccccchHHHHHHHHHHHHHHhccCHHHHHHHHHCCHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcC
Confidence            44555555554      4556778888999988865433333344456788888888764  466788889999988865


Q NP_000290.2     318 STTNKLETRRQNGIREAVSLLRR-----TG---NAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       318 ~~~~~~~ll~~~IL~~Ll~lL~s-----s~---d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~  381 (747)
                      .......+...+.++.|+.++..     ..   .......++.+|..++........++. ++++.|+.+|+.
T Consensus       278 ~~~~r~~l~~~g~I~~LL~lL~~y~~~d~~~~~e~e~~en~~~aL~~L~~~~~~r~~f~~~~gv~lLv~lL~~  350 (568)
T 4HM9_A          278 NDENRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLRE  350 (568)
T ss_dssp             CHHHHHHHHHTTHHHHHHHHHGGGTTSCCSSSHHHHHHHHHHHHHHHHTTSTHHHHHHHHTTHHHHHHHHHHH
T ss_pred             CHHHHHHHHhCchHHHHHHHHHhhhccCCCCHHHHHHHHHHHHHHHHHhCCHHHHHHHHHCChHHHHHHHHhC
Confidence            44444444445677777777731     11   123444557788887766555555555 778888888875


No 374
>5FRP_A SISTER CHROMATID COHESION PROTEIN PDS5; CELL CYCLE, CELL DIVISION, COHESIN; 2.895A {SACCHAROMYCES CEREVISIAE}
Probab=83.43  E-value=0.082  Score=57.48  Aligned_cols=149  Identities=7%  Similarity=0.080  Sum_probs=99.6  Template_Neff=9.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      +++.|...+. +.++.++..|+.+|..+....+.   . .... ....+++.++..+.+.++.++..++.++..+... +
T Consensus       282 vl~~L~~~l~-~~~~~vR~~A~~~L~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~d~~~~vR~~a~~~l~~~~~~~~  355 (703)
T 5FRP_A          282 VIGFIYHELS-SENELFRKEATKLIGQILTSYSD---L-NFVS-THSDTFKAWISKIADISPDVRVEWTESIPQIIATRE  355 (703)
T ss_dssp             THHHHHHHHT-CSSHHHHHHHHHHHHHHTTSCCS---S-CHHH-HTHHHHHHHHGGGGCSSHHHHHHHHHTHHHHHHHCC
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCCC---c-CHHH-HCHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHcCH
Confidence            5666666676 46778899999999988764221   0 0011 1245667777777778889999999999988764 2


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ..    ...+++.+...+.+      .++.++..|+.+|+.+.....  .........++.+...+.+. +..++..|+.
T Consensus       356 ~~----~~~i~~~l~~~l~D------~d~~VR~~A~~~L~~~~~~~~--~~~~~~~~~l~~l~~~l~d~-~~~VR~~A~~  422 (703)
T 5FRP_A          356 DI----SKELNQALAKTFID------SDPRVRRTSVMIFNKVPVTEI--WKNITNKAIYTSLLHLAREK-HKEVRELCIN  422 (703)
T ss_dssp             SC----SSHHHHHHHHHTTC------SSHHHHHHHHHHHHHSCHHHH--HHHCCCHHHHHHHHHGGGBS-CHHHHHHHHH
T ss_pred             HH----HHHHHHHHHHHhcC------CCHHHHHHHHHHHhhcChhHH--hhcCCchHHHHHHHHHHhcC-CHHHHHHHHH
Confidence            11    22356666677666      478999999999998865311  00111234567777777766 7789999999


Q NP_000290.2     707 LLSDMWSSK  715 (747)
Q Consensus       707 aLsnL~~~~  715 (747)
                      +|..+....
T Consensus       423 ~L~~l~~~~  431 (703)
T 5FRP_A          423 TMAKFYSNS  431 (703)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHH
Confidence            888777543


No 375
>5GM6_G Prp8, Brr2, Snu114, Rse1, Cus1; spliceosome, RNA splicing, Bact, Catalytically; HET: GTP, ADP, ZN; 3.5A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=83.42  E-value=0.077  Score=58.66  Aligned_cols=69  Identities=9%  Similarity=-0.111  Sum_probs=31.7  Template_Neff=11.400

Q NP_000290.2     248 PKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVF  316 (747)
Q Consensus       248 ~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~  316 (747)
                      +.+...+.+.++.++..++.++..+...............+++.+...+.+.+..++..++.++..++.
T Consensus       603 ~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~l~~~l~~~l~~~~~~v~~~a~~~l~~l~~  671 (971)
T 5GM6_G          603 STILNHLKHKTPLVRQHAADLCAILIPVIKNCHEFEMLNKLNIILYESLGEVYPEVLGSIINAMYCITS  671 (971)
T ss_pred             HHHHHHhcCCCHHHHHHHHHHHHHHHHHHhhcchHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHh
Confidence            333344444455566666665555543211111100111234444444444445566666666666554


No 376
>5ZWM_1 Pre-mRNA-splicing factor 8, U4/U6 small; spliceosome, assembly, pre-B complex, U1; HET: GTP; 3.4A {Saccharomyces cerevisiae S288c}
Probab=83.42  E-value=0.077  Score=58.66  Aligned_cols=69  Identities=9%  Similarity=-0.111  Sum_probs=31.7  Template_Neff=11.400

Q NP_000290.2     248 PKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVF  316 (747)
Q Consensus       248 ~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~  316 (747)
                      +.+...+.+.++.++..++.++..+...............+++.+...+.+.+..++..++.++..++.
T Consensus       603 ~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~l~~~l~~~l~~~~~~v~~~a~~~l~~l~~  671 (971)
T 5ZWM_1          603 STILNHLKHKTPLVRQHAADLCAILIPVIKNCHEFEMLNKLNIILYESLGEVYPEVLGSIINAMYCITS  671 (971)
T ss_dssp             HHHHHHTTCSSHHHHHHHHHHHHHHHHHHHHTTCHHHHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHhcCCCHHHHHHHHHHHHHHHHHHhhcchHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHh
Confidence            333344444455566666665555543211111100111234444444444445566666666666554


No 377
>3TJZ_B ADP-ribosylation factor 1, Coatomer subunit; protein trafficking, Golgi membrane, protein; HET: GNP; 2.9A {Saccharomyces cerevisiae}
Probab=83.38  E-value=0.075  Score=50.15  Aligned_cols=102  Identities=16%  Similarity=0.082  Sum_probs=56.5  Template_Neff=12.100

Q NP_000290.2     596 GLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL  675 (747)
Q Consensus       596 iI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~  675 (747)
                      .++.+..++.+.+..++..++.+|..+......   ....+++.+..++.+      .++.++..++.+|..+....+..
T Consensus       251 ~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~---~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~  321 (355)
T 3TJZ_B          251 LFDFIESCLRNKHEMVVYEAASAIVNLPGCSAK---ELAPAVSVLQLFCSS------PKAALRYAAVRTLNKVAMKHPSA  321 (355)
T ss_pred             HHHHHHHHhCCCCHHHHHHHHHHHHHHccCCHH---HHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHcCHHH
Confidence            445555556555666666666666666543100   001233444444444      25667777778877776532211


Q NP_000290.2     676 AKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMW  712 (747)
Q Consensus       676 ~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~  712 (747)
                      .     ...++.+..++.+. +..++..|+.+|..+.
T Consensus       322 ~-----~~~~~~l~~~l~~~-~~~vr~~a~~~L~~l~  352 (355)
T 3TJZ_B          322 V-----TACNLDLENLVTDA-NRSIATLAITTLLKTG  352 (355)
T ss_pred             H-----HHHHHHHHHHhcCC-CHHHHHHHHHHHHHhh
Confidence            1     12335566666655 6677888888777764


No 378
>6CRI_R Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=83.30  E-value=0.075  Score=53.54  Aligned_cols=101  Identities=12%  Similarity=0.040  Sum_probs=51.9  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++..+..+....       ....+++.+...+.+.++.++..++.++..+....+...   
T Consensus       100 ~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~-------~~~~~~~~l~~~l~~~~~~vr~~a~~~L~~~~~~~~~~~---  169 (585)
T 6CRI_R          100 MTNCIKNDLNHSTQFVQGLALCTLGCMGSSE-------MCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELM---  169 (585)
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHhhCCHH-------HHHHHHHHHHHHHhCCChHHHHHHHHHHHHHHHHCHHHH---
Confidence            4444444555555566666666665554211       011234445555555556666666666666654322111   


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                        ..+++.+...+. +.++.++..++.++..+..
T Consensus       170 --~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~  200 (585)
T 6CRI_R          170 --EMFLPATKNLLN-EKNHGVLHTSVVLLTEMCE  200 (585)
T ss_pred             --HHHHHHHHHHHc-CCCHHHHHHHHHHHHHHHH
Confidence              234445555554 4455666666666666654


No 379
>6U62_A Regulatory-associated protein of mTOR, Ras-related; signaling complex, GTPase, lysosome, SIGNALING; HET: GDP, GTP;{Homo sapiens}
Probab=83.02  E-value=0.095  Score=62.46  Aligned_cols=159  Identities=10%  Similarity=0.013  Sum_probs=98.7  Template_Neff=8.000

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSN  621 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsn  621 (747)
                      ...|+++.++++|++ ...+.+...+.+...++.-+..     ....+++.+....++.+|....  +..+..++.+|+.
T Consensus       468 l~~gifp~~~~ll~~-~~~~~~~~l~~iw~kil~~d~~-----~~~~l~~~~~~~~f~~~l~~~~~~~~~~~~~afiLa~  541 (1392)
T 6U62_A          468 LSVGIFPYVLKLLQS-SARELRPLLVFIWAKILAVDSS-----CQADLVKDNGHKYFLSVLADPYMPAEHRTMTAFILAV  541 (1392)
T ss_dssp             HHHTCHHHHHHGGGC-CCSTTHHHHHHHHHHHHTTCGG-----GHHHHHHTTTHHHHHHHHHSTTSCSSSHHHHHHHHHH
T ss_pred             HHcCcHHHHHHHHHc-cchhhHHHHHHHHHHHHhhCch-----hHHHHHhccchHHHHHhhcCCCCChhHHHHHHHHHHH
Confidence            466778888888873 4445554445555555443221     1222234444555666665432  2244566667777


Q NP_000290.2     622 MSRH-PLLH-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPK  699 (747)
Q Consensus       622 La~~-~e~~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~e  699 (747)
                      ++.. .... .....+++..+...|..      .++.++..++-+|+.|....+..+...+..+....|..++.+. .++
T Consensus       542 ~~~~~~~~q~~~~~~~~~~~~~~~l~~------~~~~~r~W~~l~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~d~-~pe  614 (1392)
T 6U62_A          542 IVNSYHTGQEACLQGNLIAICLEQLND------PHPLLRQWVAICLGRIWQNFDSARWCGVRDSAHEKLYSLLSDP-IPE  614 (1392)
T ss_dssp             HSTTCHHHHHHHHHTTHHHHHHTSTTC------SCHHHHHHHHHHHHHHSSSCHHHHHHHHTTTHHHHSGGGGGCS-STT
T ss_pred             HHhhCcchHHHHHhchHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCHHHHHHhhcccHHHHHHHHhcCC-CHH
Confidence            7754 2222 22233455666666654      3688899999999999876555555555555667788888877 899


Q NP_000290.2     700 AAEAARLLLSDMWSSK  715 (747)
Q Consensus       700 Vr~aAL~aLsnL~~~~  715 (747)
                      ||.+|+.+|+.++...
T Consensus       615 VRaaav~aL~~~i~~~  630 (1392)
T 6U62_A          615 VRCAAVFALGTFVGNS  630 (1392)
T ss_dssp             HHHHHHHHHHHHSCCT
T ss_pred             HHHHHHHHHHHhhCCC
Confidence            9999999998887553


No 380
>6BCX_W mTOR, Target of rapamycin complex; PIKK, TRANSFERASE; HET: ATP; 3.0A {Homo sapiens}
Probab=82.82  E-value=0.098  Score=62.11  Aligned_cols=159  Identities=10%  Similarity=0.013  Sum_probs=98.0  Template_Neff=7.900

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSN  621 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsn  621 (747)
                      ...|+++.++++|++ ...+.+...+.+...++.-+..     ....+++.+....++.+|....  +..+..++.+|+.
T Consensus       476 l~~gifp~~~~ll~~-~~~~~~~~l~~iw~kil~~d~~-----~~~~l~~~~~~~~f~~~l~~~~~~~~~~~~~a~iLa~  549 (1343)
T 6BCX_W          476 LSVGIFPYVLKLLQS-SARELRPLLVFIWAKILAVDSS-----CQADLVKDNGHKYFLSVLADPYMPAEHRTMTAFILAV  549 (1343)
T ss_dssp             HHHTCHHHHHHGGGC-CCGGGHHHHHHHHHHHHHHCGG-----GHHHHHHTTHHHHHHHHHTCTTSCHHHHHHHHHHHHH
T ss_pred             HHcCcHHHHHHHHHc-cchhhHHHHHHHHHHHHhhCcc-----hHHHHHhccchhHHHHhhcCCCCChhHHHHHHHHHHH
Confidence            356778888888873 4444544444455555443221     1222234444555666665432  2234566667777


Q NP_000290.2     622 MSRH-PLLH-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPK  699 (747)
Q Consensus       622 La~~-~e~~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~e  699 (747)
                      ++.. .... .....+++..+...|..      .++.++..++-+|+.|....+..+...+..+....+..++.+. .++
T Consensus       550 ~~~~~~~~q~~~~~~~~~~~~~~~l~~------~~~~~r~W~~l~l~~l~~~~~~~~~~~~~~~~~~~~~~~l~d~-~pe  622 (1343)
T 6BCX_W          550 IVNSYHTGQEACLQGNLIAICLEQLND------PHPLLRQWVAICLGRIWQNFDSARWCGVRDSAHEKLYSLLSDP-IPE  622 (1343)
T ss_dssp             HSTTCHHHHHHHHHTTHHHHHHHTTTC------SCHHHHHHHHHHHHHHTTTCHHHHHHHHHHTHHHHHGGGGGCS-SHH
T ss_pred             HHhhCchhHHHHHhchHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCHHHHHHhhcccHHHHHHHHhcCC-CHH
Confidence            7654 2222 22333456666666654      3688899999999999876555555555555667788888877 899


Q NP_000290.2     700 AAEAARLLLSDMWSSK  715 (747)
Q Consensus       700 Vr~aAL~aLsnL~~~~  715 (747)
                      ||.+++.+|+.++...
T Consensus       623 vRaa~v~aL~~~i~~~  638 (1343)
T 6BCX_W          623 VRCAAVFALGTFVGNS  638 (1343)
T ss_dssp             HHHHHHHHHHHHHTTC
T ss_pred             HHHHHHHHHHHhhCCC
Confidence            9999999998887653


No 381
>4QMH_A LP04448p; PROTEIN BINDING, TOG DOMAIN; 1.652A {Drosophila melanogaster}
Probab=82.76  E-value=0.081  Score=45.96  Aligned_cols=114  Identities=8%  Similarity=0.065  Sum_probs=67.9  Template_Neff=12.700

Q NP_000290.2     595 KGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ  674 (747)
Q Consensus       595 giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e  674 (747)
                      .+++.+...+.+.++.++..++.+|..+.............+++.+...+.+      .++.++..++.++..++.....
T Consensus        17 ~l~~~l~~~l~~~~~~~r~~a~~~l~~~~~~~~~~~~~~~~~~~~l~~~l~d------~~~~v~~~a~~~l~~l~~~~~~   90 (241)
T 4QMH_A           17 QITEALLKEMSDKDWKTRNEGLTKLQAIISEARLIKPSIGDLAPALAHRLVD------SNAKIAQTTLAICEQLATAMGA   90 (241)
T ss_dssp             GSCHHHHHHHTCSSHHHHHHHHHHHHHHHHHHCSBCSCCTTHHHHHHHHHTC------SSHHHHHHHHHHHHHHHHHHGG
T ss_pred             HhhHHHHHhcCCccHHHHHHHHHHHHHHHHhCCcCcccHHHHHHHHHHHHcC------CCHHHHHHHHHHHHHHHHHhcH
Confidence            3455566666677778888888888888764211110112345555666655      3678888888888888764322


Q NP_000290.2     675 LAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       675 ~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      ...... ..+++.+...+.+. +..++..++.+|..+.....
T Consensus        91 ~~~~~~-~~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~~~~~  130 (241)
T 4QMH_A           91 GCRNHV-RNLFPGFLHALGDN-KSFVRAAALNCINSFGEKGG  130 (241)
T ss_dssp             GGGGGH-HHHHHHHHHHTTCS-SHHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHH-HHHHHHHHHHhcCC-cHHHHHHHHHHHHHHHHhcC
Confidence            111111 23455666666554 55677777777777665443


No 382
>6QH5_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=82.76  E-value=0.083  Score=54.05  Aligned_cols=140  Identities=15%  Similarity=0.148  Sum_probs=92.9  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+. +.+..++..++.++..+......        .  ...+++.+...+.+.++.++..++.+|..+.....
T Consensus        75 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~al~~l~~~~~~~~  143 (621)
T 6QH5_A           75 GHMEAVNLLS-SNRYTEKQIGYLFISVLVNSNSE--------L--IRLINNAIKNDLASRNPTFMGLALHCIANVGSREM  143 (621)
T ss_pred             hHHHHHHHhc-CCCHHHHHHHHHHHHHHhhcCHH--------H--HHHHHHHHHHHhcCCCHHHHHHHHHHHHHhcCHHH
Confidence            4556667776 46677888888888887653221        1  12355666777777788899999999888764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                           ...+++.+...+  .+      .++.++..++.+|..+....+..   +.....++.+..++.+. ++.++..++
T Consensus       144 -----~~~l~~~l~~~l~~~~------~~~~vr~~a~~~L~~l~~~~~~~---~~~~~~~~~l~~~l~~~-~~~vr~~a~  208 (621)
T 6QH5_A          144 -----AEAFAGEIPKILVAGD------TMDSVKQSAALCLLRLYRTSPDL---VPMGDWTSRVVHLLNDQ-HLGVVTAAT  208 (621)
T ss_pred             -----HHHHHHHHHHHhcCCC------CCHHHHHHHHHHHHHHHHhChHH---ccHHHHHHHHHHHhcCC-CHHHHHHHH
Confidence                 112445555666  44      36788999999999887642221   11234567777777766 778888888


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .+|..+..
T Consensus       209 ~~L~~l~~  216 (621)
T 6QH5_A          209 SLITTLAQ  216 (621)
T ss_pred             HHHHHHHH
Confidence            88888775


No 383
>6EMK_C Serine/threonine-protein kinase TOR2 (E.C.2.7.1.67,2.7.11.1), Target; target of rapamycin, torc2, FRB; 8.0A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=82.75  E-value=0.086  Score=64.86  Aligned_cols=71  Identities=13%  Similarity=0.124  Sum_probs=44.6  Template_Neff=11.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLE-ACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~-~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      +++.|+..+. +.+..++. .++.+|..++.....     ....+ -..+++.+...+.+.+..++..++.+|..++..
T Consensus       922 ~~~~L~~~l~-d~~~~v~~~~a~~~L~~i~~~~~~-----~~~~~-l~~l~~~l~~~l~~~~~~vr~~~~~~L~~l~~~  993 (2474)
T 6EMK_C          922 VIHNLMKILN-DPSLSIHHTAAIQAIMHIFQNLGL-----RCVSF-LDQIIPGIILVMRSCPPSQLDFYFQQLGSLISI  993 (2474)
T ss_dssp             TTCCCCCCTT-CCCCCCCCCCCTTTCCCCCCCCCC-----CCCCC-SSTTCCCCCCCCCCCCHHHHCCCCCCTTTCCCC
T ss_pred             HHHHHHHHHc-CCchHHHHHHHHHHHHHHHHHcch-----hhHHh-HhhHHHHHHHHHhhCCHHHHHHHHHHHHHHHHH
Confidence            4566667776 34555555 778888887764221     01111 134566677777666677888888888888764


No 384
>5MU7_A Coatomer subunit beta, Coatomer subunit; coatomer, COPI, beta COP, delta; 2.57A {Chaetomium thermophilum var. thermophilum DSM 1495}
Probab=82.68  E-value=0.082  Score=49.28  Aligned_cols=71  Identities=11%  Similarity=-0.055  Sum_probs=38.3  Template_Neff=12.800

Q NP_000290.2     548 AIRTYLNLM-GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       548 ~I~~LL~LL-~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      .++.++..+ . ++++.++..++.+|..+......   . .... .....++.+...+.+.++.++..++.+|..+..
T Consensus        39 ~~~~l~~~l~~-~~~~~~r~~a~~~l~~~~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~  110 (373)
T 5MU7_A           39 LLMHIIRFVMP-SKSKPLKKLLYFYYEICPKLDSQ---G-KLKQ-EFILVCNGIRNDLQHPNEYIRGNTLRFLCKLRE  110 (373)
T ss_dssp             GHHHHHHHTTT-CCCHHHHHHHHHHHHHSCCBCTT---S-CBCT-HHHHHHHHHHHHTTCSSHHHHHHHHHHHTTCCC
T ss_pred             HHHHHHHHHcC-CCChhhHHHHHHHHHhccccCCc---c-hHHH-HHHHHHHHHHHHccCCCHHHHHHHHHHHHhccC
Confidence            345555553 4 35666777777777776542111   0 0000 012345556666666666777777777766543


No 385
>6CRI_I Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=82.65  E-value=0.081  Score=52.06  Aligned_cols=145  Identities=12%  Similarity=0.047  Sum_probs=93.3  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      .++.+...+. +.++.++..++.+|..+......        .....++++.+...+.+.++.++..++.+|..+.... 
T Consensus       109 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~--------~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  179 (570)
T 6CRI_I          109 LCEPLRKCLK-DEDPYVRKTAAVCVAKLHDINAQ--------LVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESHP  179 (570)
T ss_dssp             SHHHHHHHHT-CSSHHHHHHHHHHHHHHHHHCHH--------HHHHHTHHHHHHHHHTSSSHHHHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHhcC-CCCHHHHHHHHHHHHHHHHhChh--------hhhccchHHHHHHHhcCCCHHHHHHHHHHHHHHHhhCC
Confidence            4556667776 46778888999999988764321        1112456778888888888899999999999888652 


Q NP_000290.2     627 L-LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e-~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      . ........+++.+...+.+      .++.++..++.+|..+.......     ....++.+...+.+. ++.++..++
T Consensus       180 ~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~~~~~~~~~-----~~~~~~~l~~~l~~~-~~~vr~~a~  247 (570)
T 6CRI_I          180 SSNLLDLNPQSINKLLTALNE------CTEWGQIFILDCLANYMPKDDRE-----AQSICERVTPRLSHA-NSAVVLSAV  247 (570)
T ss_dssp             STTCCCCCHHHHHHHHHHHTT------SCHHHHHHHHHHTTTCCCSSHHH-----HHHHHHHHGGGGGBS-CHHHHHHHH
T ss_pred             CcchhccCHHHHHHHHHHhhc------CCHHHHHHHHHHHHHhCCCCHHH-----HHHHHHHHHHHhcCC-CHHHHHHHH
Confidence            1 1111112355555555554      25677778888888877542211     112455556666655 677788888


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .++..+..
T Consensus       248 ~~l~~l~~  255 (570)
T 6CRI_I          248 KVLMKFME  255 (570)
T ss_dssp             HHHHHHTT
T ss_pred             HHHHHHHH
Confidence            87777764


No 386
>4QMI_B Cytoskeleton-associated protein 5; PROTEIN BINDING, TOG domain; 1.9A {Homo sapiens}
Probab=82.55  E-value=0.084  Score=45.96  Aligned_cols=112  Identities=11%  Similarity=0.091  Sum_probs=68.9  Template_Neff=12.600

Q NP_000290.2     595 KGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP  673 (747)
Q Consensus       595 giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~  673 (747)
                      .+++.+...+.+.++.++..++.++..+...... ...+ ..+++.+...+.+      .++.++..++.++..++...+
T Consensus        19 ~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~~~~~~~~~~-~~~~~~l~~~l~d------~~~~vr~~a~~~l~~l~~~~~   91 (240)
T 4QMI_B           19 KITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNI-GELPTALKGRLND------SNKILVQQTLNILQQLAVAMG   91 (240)
T ss_dssp             GSCHHHHHHHTCSSHHHHHHHHHHHHHHHHHHCSBCSCC-TTHHHHHHHHTTC------SSHHHHHHHHHHHHHHHHHHG
T ss_pred             hccHHHHHHhcCCCHHHHHHHHHHHHHHHcCchHhccch-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhc
Confidence            3455666667777788888888888888765211 1111 2345556666655      367888888888888876532


Q NP_000290.2     674 QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       674 e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ....... ...++.++..+.+. +..++..++.++..+....
T Consensus        92 ~~~~~~~-~~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~~~~  131 (240)
T 4QMI_B           92 PNIKQHV-KNLGIPIITVLGDS-KNNVRAAALATVNAWAEQT  131 (240)
T ss_dssp             GGGGGGC-CCCCHHHHHHTTCS-SHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHH-HHHHHHHHHHhhcC-CHHHHHHHHHHHHHHHHHh
Confidence            2111111 23456666666655 5667777777777776553


No 387
>4QMJ_A Cytoskeleton-associated protein 5; PROTEIN BINDING, TOG DOMAIN; 2.498A {Homo sapiens}
Probab=82.55  E-value=0.084  Score=45.96  Aligned_cols=112  Identities=11%  Similarity=0.091  Sum_probs=68.9  Template_Neff=12.600

Q NP_000290.2     595 KGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP  673 (747)
Q Consensus       595 giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~  673 (747)
                      .+++.+...+.+.++.++..++.++..+...... ...+ ..+++.+...+.+      .++.++..++.++..++...+
T Consensus        19 ~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~~~~~~~~~~-~~~~~~l~~~l~d------~~~~vr~~a~~~l~~l~~~~~   91 (240)
T 4QMJ_A           19 KITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNI-GELPTALKGRLND------SNKILVQQTLNILQQLAVAMG   91 (240)
T ss_dssp             TSCHHHHHHHTCSSHHHHHHHHHHHHHHHHHHSSBCSCC-TTHHHHHHHHTTC------SSHHHHHHHHHHHHHHHHHHG
T ss_pred             hccHHHHHHhcCCCHHHHHHHHHHHHHHHcCchHhccch-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhc
Confidence            3455666667777788888888888888765211 1111 2345556666655      367888888888888876532


Q NP_000290.2     674 QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       674 e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ....... ...++.++..+.+. +..++..++.++..+....
T Consensus        92 ~~~~~~~-~~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~~~~  131 (240)
T 4QMJ_A           92 PNIKQHV-KNLGIPIITVLGDS-KNNVRAAALATVNAWAEQT  131 (240)
T ss_dssp             GGGGGGC-CCCCHHHHHGGGCS-SHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHH-HHHHHHHHHHhhcC-CHHHHHHHHHHHHHHHHHh
Confidence            2111111 23456666666655 5667777777777776553


No 388
>6MZG_E Tubulin alpha-1A chain, Tubulin beta; Microtubule, Tubulin, Tubulin polymerization, Heat; HET: GTP, GDP; 3.208A {Sus scrofa}
Probab=82.53  E-value=0.084  Score=52.43  Aligned_cols=147  Identities=12%  Similarity=0.077  Sum_probs=92.8  Template_Neff=12.700

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQ--LIGLKEKGLPQIARLL-QSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~--~llie~giI~~Ll~LL-~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ++.+...+. +.++.++..++..|..++.....   . ..  .. .-..+++.+...+ .+.++.++..++.++..++..
T Consensus       315 ~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~---~-~~~~~~-~~~~i~~~l~~~l~~d~~~~v~~~a~~~l~~l~~~  388 (554)
T 6MZG_E          315 PADFQTRIS-STKWKDRVEALEEIHNNVLKPVK---K-LAHKNQ-DYSDYLRVLANVIQKDANVQAVTIAANSVQLLCNS  388 (554)
T ss_dssp             CSTTTTTTT-CSCHHHHHHHHHHCCCCCCTTCS---C-BCCSSC-CTHHHHHHHHHHHHHCSCHHHHHHHHHHHHHHHHH
T ss_pred             CHHHHHHhc-CCCHHHHHHHHHHHHHhhhcchh---H-HhccCC-cHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHH
Confidence            344666666 46677888899999888764221   0 00  01 1135677777777 777888999999999988865


Q NP_000290.2     626 P-LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       626 ~-e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                      . .. .......+++.+...+.+      .+..++..++.+|..++....       ...+++.+...+.+. ++.++..
T Consensus       389 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~-------~~~~~~~l~~~l~~~-~~~vr~~  454 (554)
T 6MZG_E          389 LRSNFTRSYGAIVLVPLLERTKE------KKPSVNEAICSALDAVATYCG-------FDDCLEETLNYMKHK-TPQVRIE  454 (554)
T ss_dssp             STTCCSSHHHHHHHHHHHHGGGC------CCHHHHHHHHHHHHHHHTTSS-------SSSHHHHHHHHHTCS-CHHHHHH
T ss_pred             hhccccHHHHHhhHHHHHHHhhh------ccHHHHHHHHHHHHHHHHHcC-------HHHHHHHHHHHhcCC-CHHHHHH
Confidence            1 11 101112356666666655      256788888888888876421       123455666666554 6778888


Q NP_000290.2     704 ARLLLSDMWSSK  715 (747)
Q Consensus       704 AL~aLsnL~~~~  715 (747)
                      ++.+|..++...
T Consensus       455 ~~~~l~~l~~~~  466 (554)
T 6MZG_E          455 CTKFLTRMLQGW  466 (554)
T ss_dssp             HHHHHHHHHHTC
T ss_pred             HHHHHHHHHccC
Confidence            888888776543


No 389
>1B3U_A PROTEIN PHOSPHATASE PP2A, 65 KD; SCAFFOLD PROTEIN, PP2A, PHOSPHORYLATION, HEAT; 2.3A {Homo sapiens} SCOP: a.118.1.2
Probab=82.32  E-value=0.085  Score=51.84  Aligned_cols=147  Identities=13%  Similarity=0.119  Sum_probs=94.4  Template_Neff=13.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.+...+. +.++.++..++.+|..+......       .. ....+++.+...+.+.++.++..++.++..+....
T Consensus       164 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-------~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~  234 (588)
T 1B3U_A          164 ELRQYFRNLCS-DDTPMVRRAAASKLGEFAKVLEL-------DN-VKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLL  234 (588)
T ss_dssp             HHHHHHHHHHT-CSCHHHHHHHHHHHHHHHHTSCH-------HH-CCCCCHHHHHHHHTCSCHHHHTTHHHHHHHHHHHS
T ss_pred             HHHHHHHHHcc-CCCHHHHHHHHHHHHHHHHHcCh-------hh-hhhhhHHHHHHHhcCCCHHHHHHHHHHHHHHHHhC
Confidence            35566667776 46778888898888888763221       11 12456677777777778888999999888887641


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ... .....+++.+..++.+      .++.++..++.++..+....+.   .......++.+...+.+. ++.++..++.
T Consensus       235 ~~~-~~~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~~~~~~~~---~~~~~~~~~~l~~~l~~~-~~~~r~~a~~  303 (588)
T 1B3U_A          235 PQE-DLEALVMPTLRQAAED------KSWRVRYMVADKFTELQKAVGP---EITKTDLVPAFQNLMKDC-EAEVRAAASH  303 (588)
T ss_dssp             CHH-HHHHHTHHHHHHHHTC------SSHHHHHHHHHTHHHHHHHHCH---HHCCCCCHHHHHHHHTCS-SHHHHHHHHH
T ss_pred             CHH-HHHHHHHHHHHHHHhC------CCHHHHHHHHhhHHHHHHHHCC---CCCHHhHHHHHHHHhccC-HHHHHHHHHH
Confidence            111 1112345556666655      3677888888888888754221   111224566666666655 6778888888


Q NP_000290.2     707 LLSDMWS  713 (747)
Q Consensus       707 aLsnL~~  713 (747)
                      ++..+..
T Consensus       304 ~l~~l~~  310 (588)
T 1B3U_A          304 KVKEFCE  310 (588)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            8877765


No 390
>2OF3_A ZYG-9; Multifunctional macromolecule, Kinetochore, microtubule, XMAP215; 1.9A {Caenorhabditis elegans}
Probab=81.96  E-value=0.098  Score=48.11  Aligned_cols=150  Identities=9%  Similarity=-0.036  Sum_probs=91.9  Template_Neff=11.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....  .........-..+++.++..+.+.+..++..+..+|..+.....
T Consensus        88 l~~~l~~~l~-d~~~~v~~~a~~~l~~l~~~~~~--~~~~~~~~~~~~ll~~l~~~l~d~~~~vr~~a~~~l~~l~~~~~  164 (266)
T 2OF3_A           88 LLKWCTLRFF-ETNPAALIKVLELCKVIVELIRD--TETPMSQEEVSAFVPYLLLKTGEAKDNMRTSVRDIVNVLSDVVG  164 (266)
T ss_dssp             HHHHHHHHTT-SCCHHHHHHHHHHHHHHHHHHHH--TTCCCCHHHHHHHHHHHHHGGGCSSHHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHHHHHh-CCCHHHHHHHHHHHHHHHHHHHh--CCCCCCHHHHHhHHHHHHHHhCCCcHHHHHHHHHHHHHHHHhhC
Confidence            3455555666 46677888888888888764221  00000000013456677777777777788888888887765421


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .     ..+++.+...+.+      .++.++..++.+|..+...........  ..+++.+...+.+. ++.++..++.+
T Consensus       165 ~-----~~~~~~l~~~l~~------~~~~~r~~~l~~l~~~~~~~~~~~~~~--~~ii~~l~~~l~d~-~~~VR~~a~~~  230 (266)
T 2OF3_A          165 P-----LKMTPMLLDALKS------KNARQRSECLLVIEYYITNAGISPLKS--LSVEKTVAPFVGDK-DVNVRNAAINV  230 (266)
T ss_dssp             H-----HHHHHHHHHGGGC------SCHHHHHHHHHHHHHHHHHHCSGGGGG--GCHHHHHGGGGGCS-SHHHHHHHHHH
T ss_pred             H-----HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhCCccccc--ChHHHHHHHHHcCC-CHHHHHHHHHH
Confidence            1     1234445555544      357778888888888775432211111  34667777777766 78899999999


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      +..+...
T Consensus       231 l~~l~~~  237 (266)
T 2OF3_A          231 LVACFKF  237 (266)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            8888754


No 391
>4I5L_D PP2A A alpha subunit (9-589); EF Hand, Phosphatase, CDC6 (Substrate); HET: FGA, ACB, DAL, MLI, PEG, 1ZN, MAA; 2.43A {Microcystis aeruginosa}
Probab=81.77  E-value=0.092  Score=51.50  Aligned_cols=147  Identities=13%  Similarity=0.130  Sum_probs=94.5  Template_Neff=13.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.+...+. +.++.++..++.+|..+......      . . ....+++.+...+.+.++.++..++.++..+....
T Consensus       160 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~------~-~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~  230 (584)
T 4I5L_D          160 ELRQYFRNLCS-DDTPMVRRAAASKLGEFAKVLEL------D-N-VKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLL  230 (584)
T ss_dssp             HHHHHHHHHHT-CSSHHHHHHHHHHHHHHHTTSCH------H-H-CCCCCHHHHHHHTTCSCHHHHTTHHHHHHHHHHHS
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHcCh------h-h-hhcchHHHHHHHhCCCCHHHHHHHHHHHHHHHHhC
Confidence            34566667776 46778888899888888764221      1 1 12456677777787778888999999988887641


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ... .....+++.+..++.+      .++.++..++.++..+....+.   .......++.+...+.+. ++.++..++.
T Consensus       231 ~~~-~~~~~~~~~l~~~l~~------~~~~vr~~~~~~l~~l~~~~~~---~~~~~~~~~~l~~~l~~~-~~~vr~~a~~  299 (584)
T 4I5L_D          231 PQE-DLEALVMPTLRQAAED------KSWRVRYMVADKFTELQKAVGP---EITKTDLVPAFQNLMKDC-EAEVRAAASH  299 (584)
T ss_dssp             CTT-THHHHTHHHHHHHHTC------SSHHHHHHHHHTHHHHHHHHHH---HHCCCCCHHHHHHHHTCS-SHHHHHHHHT
T ss_pred             CHH-HHHHHHHHHHHHHhhC------CCHHHHHHHHHHHHHHHHHHCC---CCChhhHHHHHHHHhcCC-cHHHHHHHHH
Confidence            111 1112345556666655      3677888888888888754221   111224566666666655 6778888888


Q NP_000290.2     707 LLSDMWS  713 (747)
Q Consensus       707 aLsnL~~  713 (747)
                      ++..+..
T Consensus       300 ~l~~l~~  306 (584)
T 4I5L_D          300 KVKEFCE  306 (584)
T ss_dssp             THHHHHH
T ss_pred             HHHHHHH
Confidence            8887765


No 392
>4Y5J_A Mini spindles TOG3; XMAP215, TOG, microtubule polymerization; 2.303A {Drosophila melanogaster}
Probab=81.72  E-value=0.097  Score=46.19  Aligned_cols=71  Identities=13%  Similarity=0.043  Sum_probs=45.8  Template_Neff=12.300

Q NP_000290.2     548 AIRT-YLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIA---RLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~-LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll---~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      .++. ++..+. +.++.++..++..|..++.....     .... ....+++.+.   ..+.+.++.++..++.++..++
T Consensus        15 ~l~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~-----~~~~-~~~~l~~~l~~l~~~l~d~~~~v~~~a~~~l~~l~   87 (248)
T 4Y5J_A           15 ILPAEILNGLV-DSNWKNRLAAVEQLLGEISGFDA-----KQAG-ISQILIRTISGRKPGLKEMNFQVLKFKLDIIRSVA   87 (248)
T ss_dssp             CCCHHHHHHHH-CSSHHHHHHHHHHHHHHGGGSCT-----TSTT-HHHHHHHHHHSSSSGGGCSSHHHHHHHHHHHHHHH
T ss_pred             hcCHHHHHhhc-CcCHHHHHHHHHHHHHHHccCch-----hccc-hHHHHHHHHhcCCCchhhccHHHHHHHHHHHHHHH
Confidence            4555 777776 46778888899999888764221     0111 1123444444   5666667788888888888887


Q NP_000290.2     624 RH  625 (747)
Q Consensus       624 ~~  625 (747)
                      ..
T Consensus        88 ~~   89 (248)
T 4Y5J_A           88 EN   89 (248)
T ss_dssp             HH
T ss_pred             Hh
Confidence            54


No 393
>4P6Z_G BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=81.57  E-value=0.1  Score=53.70  Aligned_cols=137  Identities=17%  Similarity=0.119  Sum_probs=87.9  Template_Neff=12.000

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL  628 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~  628 (747)
                      +..++.++. +.+..++..++.+|..+....+.        .  ...+++.+...+.+.++.++..++.+|..+..... 
T Consensus        81 ~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~-  148 (627)
T 4P6Z_G           81 QLECLKLIA-SQKFTDKRIGYLGAMLLLDERQD--------V--HLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEM-  148 (627)
T ss_dssp             HHHHHHHHT-SSSHHHHHHHHHHHHHHCCTTSC--------C--HHHHHHHHHHHHTCSSHHHHHHHHHHHHHHCCHHH-
T ss_pred             HHHHHHHHc-CCCCchhHHHHHHHHHHCCCChH--------H--HHHHHHHHHHHhhCCCHHHHHHHHHHHHhcCCHHH-
Confidence            344556666 46677777888888777653221        1  12345566666777778888888888887764211 


Q NP_000290.2     629 HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       629 ~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                          ...+++.+..++.+      .++.++..++.+|..+....+...     ..+++.|...+.+. ++.++..++.++
T Consensus       149 ----~~~~~~~l~~~l~~------~~~~vr~~a~~~L~~l~~~~~~~~-----~~~~~~l~~~l~~~-~~~vr~~a~~~l  212 (627)
T 4P6Z_G          149 ----CRDLAGEVEKLLKT------SNSYLRKKAALCAVHVIRKVPELM-----EMFLPATKNLLNEK-NHGVLHTSVVLL  212 (627)
T ss_dssp             ----HHHHHHHHHHHHTC------SCHHHHHHHHHHHHHHHHHCSGGG-----GGGHHHHTTCTTCC-CHHHHHHHHHHH
T ss_pred             ----HHHHHHHHHHHhhC------CCHHHHHHHHHHHHHHHHHCHHHH-----HHHHHHHHHHHhCC-CHHHHHHHHHHH
Confidence                12345666666665      367888889999988876433221     24566677777655 677888888888


Q NP_000290.2     709 SDMWS  713 (747)
Q Consensus       709 snL~~  713 (747)
                      ..+..
T Consensus       213 ~~~~~  217 (627)
T 4P6Z_G          213 TEMCE  217 (627)
T ss_dssp             HHHHH
T ss_pred             HHHHH
Confidence            77754


No 394
>5KC2_B Phosphatidylinositol 3-kinase VPS34 (E.C.2.7.1.137), Serine/threonine-protein; autophagy, phosphatidylinositol 3-kinase (PtdIns3K), endocytosis; 28.0A {Saccharomyces cerevisiae}
Probab=81.46  E-value=0.11  Score=61.49  Aligned_cols=126  Identities=13%  Similarity=0.064  Sum_probs=72.5  Template_Neff=9.500

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETR  326 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll  326 (747)
                      ++.|..++.+.++.++..++.+|..+....  ....+.. ..++.|+.++.+.++.++..++.+|..+..........+.
T Consensus       621 l~~L~~~l~d~~~~vR~~a~~al~~l~~~~--~~~~~~~-~~lp~L~~lL~d~~~~vr~~al~aL~~L~~~~~~~~~~~~  697 (1454)
T 5KC2_B          621 LSHLITYLNDKDPALRVSLIQTISGISILL--GTVTLEQ-YILPLLIQTITDSEELVVISVLQSLKSLFKTGLIRKKYYI  697 (1454)
T ss_pred             HHHHHHHccCCCHHHHHHHHHHHHHHHHhh--HHHHHHH-cCHHHHHHHhcCCCHHHHHHHHHHHHHHhhCCHHHHHHHH
Confidence            444555555566667777777776666432  1112222 2266777777776777788888888877653322222221


Q NP_000290.2     327 RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRV  379 (747)
Q Consensus       327 ~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL  379 (747)
                        ..++.+..++. +.++.++..+..+|..|+...... .....+++.|+.+|
T Consensus       698 --~~l~~l~~~l~-~~~~~vr~~a~~~L~~l~~~~~~~-~~~~~~~~~L~~~L  746 (1454)
T 5KC2_B          698 --DISKTTSPLLL-HPNNWIRQFTLMIIIEIINKLSKA-EVYCILYPIIRPFF  746 (1454)
T ss_pred             --HHHHHHHHHHC-CCCHHHHHHHHHHHHHHhcCCCCH-HHHcChHHHHHHHh
Confidence              25556666665 457778888888888877643221 11134555555555


No 395
>6MZG_E Tubulin alpha-1A chain, Tubulin beta; Microtubule, Tubulin, Tubulin polymerization, Heat; HET: GTP, GDP; 3.208A {Sus scrofa}
Probab=81.15  E-value=0.1  Score=51.71  Aligned_cols=151  Identities=11%  Similarity=0.102  Sum_probs=93.6  Template_Neff=12.700

Q NP_000290.2     550 RTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR-LLQSGNSDVVRSGASLLSNMSRHPLL  628 (747)
Q Consensus       550 ~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~-LL~s~d~eVr~~AL~aLsnLa~~~e~  628 (747)
                      +.+...+. +.++.++..++.+|..++..... ........ ....+++.++. ++.+.++.++..++.+|..++.....
T Consensus        57 ~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~-~~~~~~~~-~~~~~l~~l~~~~~~~~~~~vr~~a~~~L~~l~~~~~~  133 (554)
T 6MZG_E           57 ELFASYIV-DSNVVAQENAIIALHTLLEYISQ-VPNVSTSK-LRLQWIPPLVEKGLSSSRAATKAKATDCIMLLTQSDTS  133 (554)
T ss_dssp             HHHHHHTT-CSSHHHHHHHHHHHHHHHHHTCS-SSCCTHHH-HHHHHHHHHCCCCCSCSCHHHHHHHHHHHHHHHHTSSS
T ss_pred             HHHHHhcC-CccHHHHHHHHHHHHHHHHHHhc-CCCCCcHH-HHHhcHHHHHHHhccCCcHHHHHHHHHHHHHHHhcccc
Confidence            55666776 47788899999999988764221 00000001 11345666666 45666788889999999888754111


Q NP_000290.2     629 HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK---QYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       629 ~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~---~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                          ...+++.+...+.+      .++.++..++.+|..++........   ......+++.+...+.+. ++.++..++
T Consensus       134 ----~~~~~~~l~~~l~~------~~~~vr~~~~~~l~~l~~~~~~~~~~~~~~~~~~i~~~l~~~l~~~-~~~vr~~a~  202 (554)
T 6MZG_E          134 ----IQQTVNLMLPSLSN------KLPRLVSSCVKCLATIIEEFGFINVSDINILLSEILEPLPKLSSHA-DRNVRSETM  202 (554)
T ss_dssp             ----SHHHHHHHSGGGGC------SCHHHHHHHHHHHHHHHHHTCSCSCSCHHHHHHHHHSSHHHHTTCS-SHHHHHHHH
T ss_pred             ----HHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhCCCccccccccHHHHHHHHHHHhhcC-CHHHHHHHH
Confidence                11244555555554      3677888899999888764221110   001234567777777766 788999999


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..+...
T Consensus       203 ~~l~~l~~~  211 (554)
T 6MZG_E          203 NLILQIYKW  211 (554)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHH
Confidence            998888754


No 396
>6MZE_Z Tubulin alpha-1A chain, Tubulin beta; Microtubule, Tubulin, Tubulin polymerization, Heat; HET: MG, GTP, GDP; 3.6A {Sus scrofa}
Probab=81.14  E-value=0.1  Score=51.20  Aligned_cols=108  Identities=11%  Similarity=0.069  Sum_probs=63.0  Template_Neff=12.900

Q NP_000290.2     600 IARLLQSGNSDVVRSGASLLSNMSRHPL-LHR---VMGNQVFPEVTRLL-TSHTGNTSNSEDILSSACYTVRNLMASQPQ  674 (747)
Q Consensus       600 Ll~LL~s~d~eVr~~AL~aLsnLa~~~e-~~~---ll~~giI~~Ll~LL-~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e  674 (747)
                      +...+.+.+..++..++.+|..++.... ...   .....+++.+...+ .+      .++.++..++.++..++.....
T Consensus       300 l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~d------~~~~v~~~a~~~l~~l~~~~~~  373 (536)
T 6MZE_Z          300 FQTRISSTKWKDRVEALEEIHNNVLKPVKKLAHKNQDYSDYLRVLANVIQKD------ANVQAVTIAANSVQLLCNSLRS  373 (536)
T ss_dssp             GHHHHSCSSHHHHHHHHHHCCCCCCSSCSCBCCTTCCCTTTHHHHHHHHHHC------SCHHHHHHHHHHHHHHHHHTTT
T ss_pred             HHHHhhcCCHHHHHHHHHHHHHHhhccchhhccCCCCHHHHHHHHHHHHhcC------chHHHHHHHHHHHHHHHHHccc
Confidence            4455555667778888888888775411 100   11123556666666 54      3678888899999888764322


Q NP_000290.2     675 LAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       675 ~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      .........+++.++..+.+. +..++..++.+|..++..
T Consensus       374 ~~~~~~~~~~~~~l~~~l~~~-~~~vr~~a~~~l~~l~~~  412 (536)
T 6MZE_Z          374 NFTRSYGAIVLVPLLERTKEK-KPSVNEAICSALDAVATY  412 (536)
T ss_dssp             CCSSHHHHHHHHHHHHHTTCC-CHHHHHHHHHHHHHHHHT
T ss_pred             cccHHHHHHHHHHHHHHhhcc-CHHHHHHHHHHHHHHHHh
Confidence            111011123455666666554 566777777777776654


No 397
>6RXU_UJ Periodic tryptophan protein 2-like protein; ribosome, ribosome biogenesis, rRNA; HET: GTP; 3.5A {Chaetomium thermophilum}
Probab=80.93  E-value=0.12  Score=62.49  Aligned_cols=152  Identities=9%  Similarity=0.051  Sum_probs=85.8  Template_Neff=9.700

Q NP_000290.2     548 AIRTYLNLMGKS-----KKDATLEACAGALQNLTASKGLMSSGMSQ--LIGLKEKGLPQIARLLQSG--------NSDVV  612 (747)
Q Consensus       548 ~I~~LL~LL~ss-----~d~eVr~~AL~aL~nLs~~s~~~s~~~~~--~llie~giI~~Ll~LL~s~--------d~eVr  612 (747)
                      +++.++..+...     .+..++..++.+|..++.....   ....  ..  -..+++.|...+...        ...++
T Consensus      1625 il~~ll~~L~~~~~~~~~~~~v~~~~l~~L~~l~~~~~~---~~~~~~~~--~~~ll~~L~~~L~~~~~~~~~~~~~~v~ 1699 (1802)
T 6RXU_UJ        1625 IVDASVKALKAVDFAVPEERNLWKRVLCTLAKCFEHDQD---GFWQAPAH--FGAVAPVLVEQFLRAEGQVTATNVNDVI 1699 (1802)
T ss_pred             HHHHHHHHHhcCCCCCCCCHHHHHHHHHHHHHHHHHhCh---hhhcChhH--HHHHHHHHHHHHhCCCCCCCccccHHHH
Confidence            345555555521     2456777788888877764221   0000  11  134556666666532        23567


Q NP_000290.2     613 RSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLC  692 (747)
Q Consensus       613 ~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL  692 (747)
                      ..++.+++.++.......+. ..+++.++..+.+      .++.++..++.++..++.........+. ..+++.+...+
T Consensus      1700 ~~ai~~L~~l~~~~~~~~~~-~~l~~~ll~~l~~------~~~~vR~~al~~L~~l~~~~g~~~~~~l-~~ii~~L~elL 1771 (1802)
T 6RXU_UJ        1700 QDVVPAVVELAAAVESQEHY-KEINTALLKHLRN------GSPGVRLAVVKCQQAITAKLGEDWLHLL-PEMLPYISELQ 1771 (1802)
T ss_pred             HHHHHHHHHHHHHhCCchHH-HhHHHHHHHHcCC------CCHHHHHHHHHHHHHHHHHHcHhhHHhH-HHHHHHHHHHh
Confidence            77888888877531111111 1234445555544      3567888999999988765332222222 24567777777


Q NP_000290.2     693 RSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       693 ~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      ++. ++.++..+..++..+..
T Consensus      1772 eD~-d~~V~~~a~~~l~~l~~ 1791 (1802)
T 6RXU_UJ        1772 DDD-DEVVERENRRWIVGIEE 1791 (1802)
T ss_pred             cCC-CHHHHHHHHHHHHHHHH
Confidence            766 77788888777776654


No 398
>5FVM_B SERINE/THREONINE-PROTEIN KINASE TOR2, TARGET OF; TRANSFERASE, CRYO-EM, TOR, LST8, MTOR; 6.7A {KLUYVEROMYCES MARXIANUS}
Probab=80.75  E-value=0.12  Score=63.47  Aligned_cols=147  Identities=12%  Similarity=0.092  Sum_probs=75.7  Template_Neff=11.500

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.+...+. +  ..++..++.++..++.....     ....+ -..+++.++..+.+.+..++..++.++..+.....
T Consensus      1008 i~~~l~~~l~-~--~~vr~~a~~~l~~l~~~~~~-----~~~~~-~~~ll~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~ 1078 (2471)
T 5FVM_B         1008 IVDVISEFFP-V--LKLQLTIISVIESLSRALEG-----EFNPH-LPTILSLFLDVLEKDQSNKKVVSVRILKSLVVFGP 1078 (2471)
T ss_dssp             HHHTTC------------CTHHHHHHHHHTTSSC-----CHHHH-HHHHHHHHHHHHC----CCHHHHHHHHHHHHHHCS
T ss_pred             HHHHHHHHcc-c--hhHHHHHHHHHHHHHHHccc-----ChHHH-HHHHHHHHHHHHccCCCCcHHHHHHHHHHHHHHhh
Confidence            3444555444 1  45666778888877754221     01111 23566777777776666677777777776654321


Q NP_000290.2     628 L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       628 ~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      . ...+ ..+++.+...+.+      .++.++..++.+|..++.....  .. ....++..++..+.+. ++.++..++.
T Consensus      1079 ~~~~~l-~~il~~l~~~l~~------~~~~vr~~al~~l~~l~~~~~~--~~-~~~~i~~~l~~~l~~~-~~~vr~~a~~ 1147 (2471)
T 5FVM_B         1079 HLEEYV-HLVLPTIIKLSEF------SSGNLKKAAIITIGRLSKNVNA--LE-MSSRIVQALVRVLNTS-ETEYVKATMN 1147 (2471)
T ss_dssp             SCCCHH-HHHHHHHHTTC---------CCHHHHHHHHHHHHHHHC-CC--HH-HHHHHHHHHHHHCC---CTHHHHHHHH
T ss_pred             hHHHHH-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhhCCh--HH-HHHHHHHHHHHHHcCC-ChHHHHHHHH
Confidence            1 1111 2355666666655      2567888888888888754221  11 1124566666777655 6677888888


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      +|..++..
T Consensus      1148 ~l~~l~~~ 1155 (2471)
T 5FVM_B         1148 TLSLLLLQ 1155 (2471)
T ss_dssp             HHHHHHHC
T ss_pred             HHHHHHHH
Confidence            88777643


No 399
>6GWC_C Tubulin alpha chain, Tubulin beta; microtubule, ARTIFICIAL PROTEIN, ALPHAREP, cytoskeleton; HET: GTP, MES, PGE; 2.6A {Ovis aries}
Probab=80.69  E-value=0.11  Score=45.32  Aligned_cols=49  Identities=8%  Similarity=0.093  Sum_probs=29.6  Template_Neff=12.200

Q NP_000290.2     654 SEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       654 d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.++..++.+|..+...           ..++.+..++.+. ++.++..++.++..+...
T Consensus       120 ~~~~r~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~~~  168 (232)
T 6GWC_C          120 DTTVRRIAATALGKIGDE-----------RAVEPLIKALKDE-DAAVRLTAARALGEIGDE  168 (232)
T ss_pred             CHHHHHHHHHHHHHhccc-----------chHHHHHHHhcCC-CHHHHHHHHHHHHHhCCh
Confidence            455556666666555321           2344455566655 677888888888877653


No 400
>1OYZ_A X-RAY STRUCTURE OF YB61_HAEIN NORTHEAST; STRUCTURAL GENOMICS, PSI, Protein Structure; 2.1A {Escherichia coli} SCOP: a.118.1.16
Probab=80.56  E-value=0.11  Score=46.13  Aligned_cols=64  Identities=13%  Similarity=0.063  Sum_probs=32.1  Template_Neff=12.700

Q NP_000290.2     549 IRTYLN-LMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       549 I~~LL~-LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      ++.+.. ++. +.++.++..++.+|..+....+.          .....++.+...+.+.++.++..++.+|..+.
T Consensus        92 ~~~l~~~~l~-~~~~~vr~~a~~~l~~~~~~~~~----------~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~~~  156 (280)
T 1OYZ_A           92 FNILNNMALN-DKSACVRATAIESTAQRCKKNPI----------YSPKIVEQSQITAFDKSTNVRRATAFAISVIN  156 (280)
T ss_dssp             HHHHHHHHHH-CSCHHHHHHHHHHHHHHHHHCGG----------GHHHHHHHHHHHTTCSCHHHHHHHHHHHHTC-
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCcc----------cChhHHHHHHHHhcCCCHHHHHHHHHHHHhhc
Confidence            344444 444 34556666666666665532110          11233445555555555666666666665544


No 401
>6GX7_F Tubulin alpha chain, Tubulin beta; microtubule, ALPHAREP, CELL CYCLE, COPN; HET: MES, PGE, SO4, GOL, GTP; 3.19A {Ovis aries}
Probab=80.46  E-value=0.12  Score=44.09  Aligned_cols=122  Identities=14%  Similarity=0.214  Sum_probs=55.9  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++..+..+..                ...++.+..++.+.++.++..++.++..+...  
T Consensus        46 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~----------------~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~--  106 (201)
T 6GX7_F           46 AVEPLIKALK-DEDPWVRREAAGALGQIGD----------------ERAVEPLIKALKDEDRYVRRIAARALGKIGDE--  106 (201)
T ss_dssp             GHHHHHHHTT-CSSHHHHHHHHHHHHHHTC----------------GGGHHHHHHHTTCSSHHHHHHHHHHHHHHTCG--
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHCC----------------HHHHHHHHHHhcCCCHHHHHHHHHHHhhcCCh--
Confidence            3444555554 2445555555555544321                11233344445555555666666666555421  


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                             ..++.+...+.+      .++.++..++.++..+...           ..++.+..++.+. +..++..++.+
T Consensus       107 -------~~~~~l~~~l~~------~~~~v~~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~vr~~a~~~  161 (201)
T 6GX7_F          107 -------RAVEPLIKALKD------EDWQVREDAAKALGQIGDE-----------RAVEPLIKALKDE-DTTVRLEAALA  161 (201)
T ss_dssp             -------GGHHHHHHHTTC------SSHHHHHHHHHHHHHHTCG-----------GGHHHHHHHTTCS-SHHHHHHHHHH
T ss_pred             -------hhHHHHHHHhhc------CCHHHHHHHHHHHHHhCCH-----------HHHHHHHHHHhCC-CHHHHHHHHHH
Confidence                   122333333433      2345555555555554321           1233333444433 45555566666


Q NP_000290.2     708 LSDMWS  713 (747)
Q Consensus       708 LsnL~~  713 (747)
                      +..+..
T Consensus       162 l~~~~~  167 (201)
T 6GX7_F          162 LGKIGG  167 (201)
T ss_dssp             HHHHCS
T ss_pred             HHhhcc
Confidence            555543


No 402
>2NYL_A Protein phosphatase 2, regulatory subunit; HEAT repeat, HYDROLASE-HYDROLASE INHIBITOR COMPLEX; HET: DAL, MSE, ACB, 1ZN, DAM, FGA; 3.8A {Homo sapiens} SCOP: a.118.1.2
Probab=80.40  E-value=0.11  Score=50.67  Aligned_cols=147  Identities=13%  Similarity=0.119  Sum_probs=93.6  Template_Neff=13.500

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.+..++. +.++.++..++.++..+......       .. ....+++.+...+.+.++.++..++.++..+....
T Consensus       158 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-------~~-~~~~~~~~l~~~~~~~~~~~r~~a~~~l~~l~~~~  228 (582)
T 2NYL_A          158 ELRQYFRNLCS-DDTPMVRRAAASKLGEFAKVLEL-------DN-VKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLL  228 (582)
T ss_dssp             HHHHHHHHHHS-CSCHHHHHHHHHHHHHHHTTSCH-------HH-CCCCCHHHHHHHTSCSCHHHHHHHHHHHHHHHHHS
T ss_pred             HHHHHHHHHcc-CCCHHHHHHHHHHHHHHHHHcCh-------hh-hHhhHHHHHHHHhhCCCHHHHHHHHHHHHHHHHHC
Confidence            35566667776 46778888899988888763221       11 12456677777777777888888988888887641


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ... .....+++.+...+.+      .++.++..++.++..+....+.   .......++.+...+.+. ++.++..++.
T Consensus       229 ~~~-~~~~~~~~~l~~~l~~------~~~~vr~~~~~~l~~~~~~~~~---~~~~~~~~~~l~~~l~~~-~~~v~~~a~~  297 (582)
T 2NYL_A          229 PQE-DLEALVMPTLRQAAED------KSWRVRYMVADKFTELQKAVGP---EITKTDLVPAFQNLMKDC-EAEVRAAASH  297 (582)
T ss_dssp             CHH-HHTTTTHHHHHHHHHC------SSHHHHHHHHHTHHHHHHHHCS---HHCCCCCHHHHHHHHTCS-SHHHHHHHHT
T ss_pred             CHH-HHHHHHHHHHHHHhcC------CCHHHHHHHHHhHHHHHHHHCC---CCCHhhhHHHHHHHhcCC-hHHHHHHHHH
Confidence            111 1112345556666655      3677888888888888754221   111223566666666655 6778888888


Q NP_000290.2     707 LLSDMWS  713 (747)
Q Consensus       707 aLsnL~~  713 (747)
                      ++..+..
T Consensus       298 ~l~~~~~  304 (582)
T 2NYL_A          298 KVKEFCE  304 (582)
T ss_dssp             THHHHHH
T ss_pred             HHHHHHH
Confidence            8877765


No 403
>5VJC_B Protein mini spindles; TOG, HEAT Repeat, Tubulin, CELL; 2.0A {Drosophila melanogaster}
Probab=80.32  E-value=0.12  Score=47.18  Aligned_cols=72  Identities=13%  Similarity=0.027  Sum_probs=44.4  Template_Neff=11.500

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .+.+.+...+. +.++.++..++..|..++.....     ...... ..++..+...+.+.++.++..++.++..++..
T Consensus        50 ~~~~~l~~~l~-~~~~~~r~~a~~~L~~~~~~~~~-----~~~~~~-~~l~~~l~~~l~d~~~~vr~~a~~~l~~l~~~  121 (271)
T 5VJC_B           50 NVNKALIANMF-HDDFRYHLKVIEQLSEDLAGNSK-----ALVCNL-DLILKWLTLRFYDTNPSVLIKGLEYLVQVFQV  121 (271)
T ss_dssp             TCCHHHHHHHT-CSCHHHHHHHHHHHHHHTTTCHH-----HHHHTH-HHHHHHHHHHTTSSCHHHHHHHHHHHHHHHHH
T ss_pred             cCCHHHHHhcc-CCCHHHHHHHHHHHHHHHhcCHH-----HHHHHH-HHHHHHHHHHHhCCCHHHHHHHHHHHHHHHHH
Confidence            34566777776 46777888888888888764321     011111 23344455555566777888888888877654


No 404
>6RXV_UJ Periodic tryptophan protein 2-like protein; ribosome, ribosome biogenesis, rRNA; HET: GTP; 4.0A {Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)}
Probab=80.28  E-value=0.13  Score=62.13  Aligned_cols=152  Identities=9%  Similarity=0.051  Sum_probs=86.0  Template_Neff=9.700

Q NP_000290.2     548 AIRTYLNLMGKS-----KKDATLEACAGALQNLTASKGLMSSGMSQ--LIGLKEKGLPQIARLLQSG--------NSDVV  612 (747)
Q Consensus       548 ~I~~LL~LL~ss-----~d~eVr~~AL~aL~nLs~~s~~~s~~~~~--~llie~giI~~Ll~LL~s~--------d~eVr  612 (747)
                      +++.++..+...     .+..++..++.+|..++.....   ....  ..  -..+++.|...+...        ...++
T Consensus      1625 il~~ll~~L~~~~~~~~~~~~v~~~al~~L~~l~~~~~~---~~~~~~~~--~~~il~~L~~~L~~~~~~~~~~~~~~v~ 1699 (1802)
T 6RXV_UJ        1625 IVDASVKALKAVDFAVPEERNLWKRVLCTLAKCFEHDQD---GFWQAPAH--FGAVAPVLVEQFLRAEGQVTATNVNDVI 1699 (1802)
T ss_pred             HHHHHHHHHHhcCCCChHHHHHHHHHHHHHHHHHhcCCC---CcccChhH--HHhHHHHHHHHHHhhcCCCCCccHHHHH
Confidence            345555555521     2456777788888877764221   0000  11  134556666666532        23567


Q NP_000290.2     613 RSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLC  692 (747)
Q Consensus       613 ~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL  692 (747)
                      ..++.+++.++.......+. ..+++.++..+.+      .++.++..++.++..++.........+. ..+++.+...+
T Consensus      1700 ~~ai~~L~~l~~~~~~~~~~-~~l~~~ll~~l~~------~~~~vR~~al~~L~~l~~~~g~~~~~~l-~eii~~L~elL 1771 (1802)
T 6RXV_UJ        1700 QDVVPAVVELAAAVESQEHY-KEINTALLKHLRN------GSPGVRLAVVKCQQAITAKLGEDWLHLL-PEMLPYISELQ 1771 (1802)
T ss_pred             HHHHHHHHHHHHHcCCHHHH-HHHHHHHHHHccC------CCHHHHHHHHHHHHHHHHHHCHhHHhhh-hHHHHHHHHHh
Confidence            77888888877531111111 1234445555544      3567888999999988765332222222 24567777777


Q NP_000290.2     693 RSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       693 ~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      ++. ++.++..+..++..+..
T Consensus      1772 eD~-d~~V~~~a~~~l~~l~~ 1791 (1802)
T 6RXV_UJ        1772 DDD-DEVVERENRRWIVGIEE 1791 (1802)
T ss_pred             cCC-CHHHHHHHHHHHHHHHH
Confidence            766 77788888777776654


No 405
>4I5L_D PP2A A alpha subunit (9-589); EF Hand, Phosphatase, CDC6 (Substrate); HET: FGA, ACB, DAL, MLI, PEG, 1ZN, MAA; 2.43A {Microcystis aeruginosa}
Probab=80.24  E-value=0.11  Score=50.76  Aligned_cols=109  Identities=15%  Similarity=0.189  Sum_probs=68.2  Template_Neff=13.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      ..++.+...+. +.++.++..++.++..+......       .. ....+++.+...+.+.++.++..++.++..+... 
T Consensus       238 ~~~~~l~~~l~-~~~~~vr~~~~~~l~~l~~~~~~-------~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~  308 (584)
T 4I5L_D          238 LVMPTLRQAAE-DKSWRVRYMVADKFTELQKAVGP-------EI-TKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENL  308 (584)
T ss_dssp             HTHHHHHHHHT-CSSHHHHHHHHHTHHHHHHHHHH-------HH-CCCCCHHHHHHHHTCSSHHHHHHHHTTHHHHHHTS
T ss_pred             HHHHHHHHHhh-CCCHHHHHHHHHHHHHHHHHHCC-------CC-ChhhHHHHHHHHhcCCcHHHHHHHHHHHHHHHHhc
Confidence            35566666776 46778888888888887754221       11 1245667777778777788899999999888764 


Q NP_000290.2     626 PLL-H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       626 ~e~-~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      ... . ......+++.+...+.+      .+..++..++.++..+..
T Consensus       309 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~~~~~l~~l~~  349 (584)
T 4I5L_D          309 SADCRENVIMSQILPCIKELVSD------ANQHVKSALASVIMGLSP  349 (584)
T ss_dssp             CTTTHHHHCCCCCHHHHHHHHTC------SCHHHHHHHHTTGGGGHH
T ss_pred             CccchhhHHHHhHHHHHHHHccC------CCHHHHHHHHHHHHHHHH
Confidence            111 1 11123355555555554      245666777777766654


No 406
>1IBR_B RAN  IMPORTIN BETA SUBUNIT; SMALL GTPASE  NUCLEAR TRANSPORT; HET: GNP; 2.3A {Homo sapiens} SCOP: a.118.1.1
Probab=80.23  E-value=0.12  Score=49.62  Aligned_cols=156  Identities=10%  Similarity=0.042  Sum_probs=86.8  Template_Neff=12.900

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLM------------SSGMSQ----LIGLKEKGLPQIARLLQSG-----  607 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~------------s~~~~~----~llie~giI~~Ll~LL~s~-----  607 (747)
                      ++.+...+. +.++.++..++.++..++......            ......    .. .-..+++.+...+.+.     
T Consensus       261 ~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~l~~~l~~~l~~~~~~~~  338 (462)
T 1IBR_B          261 FAITIEAMK-SDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKG-ALQYLVPILTQTLTKQDENDD  338 (462)
T ss_dssp             HHHHHHHHH-CSSHHHHHHHHHHHHHHHHHHHHHHHHHCCTTCSSSCSSCCCCCHHHH-HHHHHHHHHHHHTTCCCSSCC
T ss_pred             HHHHHHHHh-cCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCcchhhHHhHHH-HHHHHHHHHHHhcccCCCCCC
Confidence            555666666 356777778888888776531000            000000    00 0123344444444433     


Q NP_000290.2     608 --NSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSM  684 (747)
Q Consensus       608 --d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~gi  684 (747)
                        +..++..+..++..++.....  .....+++.+...+.+      .++.++..++.++..++...+. ...... ..+
T Consensus       339 ~~~~~~r~~a~~~l~~l~~~~~~--~~~~~~~~~l~~~l~~------~~~~~r~~al~~l~~l~~~~~~~~~~~~~-~~~  409 (462)
T 1IBR_B          339 DDDWNPCKAAGVCLMLLATCCED--DIVPHVLPFIKEHIKN------PDWRYRDAAVMAFGCILEGPEPSQLKPLV-IQA  409 (462)
T ss_dssp             TTCCSHHHHHHHHHHHHHHHTTT--THHHHHHHHHHHHTTC------SSHHHHHHHHHHHHHTSSSSCTTTTCTTT-TTH
T ss_pred             CCCCCHHHHHHHHHHHHHHhccC--ccHHhHHHHHHHhccC------CCHHHHHHHHHHHHHHHhCCCHHHHHHHH-HHH
Confidence              445667777777777654111  0111234444455544      3677888999999988764332 111111 235


Q NP_000290.2     685 LNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       685 L~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      ++.+...+.+. ++.++..++.++..++....
T Consensus       410 ~~~l~~~l~d~-~~~vr~~a~~~l~~l~~~~~  440 (462)
T 1IBR_B          410 MPTLIELMKDP-SVVVRDTAAWTVGRICELLP  440 (462)
T ss_dssp             HHHHHHGGGCS-CHHHHHHHHHHHHHHHHHGG
T ss_pred             HHHHHHHcCCC-CHHHHHHHHHHHHHHHHhCh
Confidence            66677777665 78899999999998876443


No 407
>1B3U_A PROTEIN PHOSPHATASE PP2A, 65 KD; SCAFFOLD PROTEIN, PP2A, PHOSPHORYLATION, HEAT; 2.3A {Homo sapiens} SCOP: a.118.1.2
Probab=80.14  E-value=0.12  Score=50.76  Aligned_cols=109  Identities=15%  Similarity=0.181  Sum_probs=67.7  Template_Neff=13.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.+..++. +.++.++..++.++..+......       .. ....+++.+...+.+.++.++..++.++..+....
T Consensus       242 ~~~~~l~~~l~-~~~~~~r~~~~~~l~~~~~~~~~-------~~-~~~~~~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~  312 (588)
T 1B3U_A          242 LVMPTLRQAAE-DKSWRVRYMVADKFTELQKAVGP-------EI-TKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENL  312 (588)
T ss_dssp             HTHHHHHHHHT-CSSHHHHHHHHHTHHHHHHHHCH-------HH-CCCCCHHHHHHHHTCSSHHHHHHHHHHHHHHHHTS
T ss_pred             HHHHHHHHHHh-CCCHHHHHHHHhhHHHHHHHHCC-------CC-CHHhHHHHHHHHhccCHHHHHHHHHHHHHHHHHhC
Confidence            35566666776 46777888888888888754221       11 12456677777777777888889999988887641


Q NP_000290.2     627 -LL-H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       627 -e~-~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                       .. . ......+++.+...+.+      .+..++..++.++..+..
T Consensus       313 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~~~~~l~~l~~  353 (588)
T 1B3U_A          313 SADCRENVIMSQILPCIKELVSD------ANQHVKSALASVIMGLSP  353 (588)
T ss_dssp             CTTTHHHHCCCCCHHHHHHHHTC------SCHHHHHHHHTTGGGGHH
T ss_pred             CcchhhhhhHHhHHHHHHHHhcC------CCHHHHHHHHHHHHHHHH
Confidence             11 1 11113345555555554      245666667777666654


No 408
>4P6Z_G BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=80.03  E-value=0.13  Score=52.92  Aligned_cols=67  Identities=18%  Similarity=0.165  Sum_probs=48.8  Template_Neff=12.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      +++.+..++. +.++.++..++.+|..+....+.        .  ...+++.|...+.+.++.++..++.++..++..
T Consensus       152 ~~~~l~~~l~-~~~~~vr~~a~~~L~~l~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~  218 (627)
T 4P6Z_G          152 LAGEVEKLLK-TSNSYLRKKAALCAVHVIRKVPE--------L--MEMFLPATKNLLNEKNHGVLHTSVVLLTEMCER  218 (627)
T ss_dssp             HHHHHHHHHT-CSCHHHHHHHHHHHHHHHHHCSG--------G--GGGGHHHHTTCTTCCCHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHhh-CCCHHHHHHHHHHHHHHHHHCHH--------H--HHHHHHHHHHHHhCCCHHHHHHHHHHHHHHHHh
Confidence            4666777777 46778888899999888764221        1  135677777888777888888898888888654


No 409
>5NR4_A CLIP-associating protein 2; Microtubules, TOG domain, Tubulin, Structural; 1.198A {Homo sapiens}
Probab=79.96  E-value=0.12  Score=44.07  Aligned_cols=109  Identities=12%  Similarity=0.062  Sum_probs=69.2  Template_Neff=12.900

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.++.++..++.++..+........... ...+++.+...+.+.+..++..++.++..+......   
T Consensus        51 ~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~~---  126 (230)
T 5NR4_A           51 GKTVDALTGWVGSSNYRVSLMGLEILSAFVDRLSTRFKSY-VAMVIVALIDRMGDAKDKVRDEAQTLILKLMDQVAP---  126 (230)
T ss_dssp             HHHHHHHHHHHHCSSHHHHHHHHHHHHHHHHHHGGGGGGG-HHHHHHHHHHHTTCSSHHHHHHHHHHHHHHHHHTSC---
T ss_pred             HHHHHHHHHHHcCCCHHHHHHHHHHHHHHHHHhhHHHHHH-HHHHHHHHHHHhccCCHHHHHHHHHHHHHHHHcCCC---
Confidence            3455666666666778888889999888876543221111 134566666666666677788888888777653210   


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                         ...+++.+...+. +.++.++..++.++..++..
T Consensus       127 ---~~~~~~~l~~~l~-~~~~~~r~~~~~~l~~l~~~  159 (230)
T 5NR4_A          127 ---PMYIWEQLASGFK-HKNFRSREGVCLCLIETLNI  159 (230)
T ss_dssp             ---HHHHHHHHGGGGG-CSCHHHHHHHHHHHHHHHHH
T ss_pred             ---HHHHHHHHHhcCC-CCCHHHHHHHHHHHHHHHHH
Confidence               1234555555665 45667888888888877753


No 410
>2P8Q_A Importin beta-1 subunit, Snurportin-1; HEAT repeat, IBB-domain, Importin, Karyopherin; 2.35A {Homo sapiens} SCOP: a.118.1.1
Probab=79.89  E-value=0.12  Score=54.05  Aligned_cols=154  Identities=11%  Similarity=0.064  Sum_probs=92.1  Template_Neff=13.100

Q NP_000290.2     548 AIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsnLa  623 (747)
                      .++.|...+. +.+  +.++..++.+|..++.....   . .... ....+++.+...+.+.+  +.++..++.++..++
T Consensus       129 l~~~l~~~l~-~~~~~~~~~~~~~~~l~~l~~~~~~---~-~~~~-~~~~l~~~l~~~l~~~~~~~~vr~~a~~~l~~l~  202 (876)
T 2P8Q_A          129 LIPQLVANVT-NPNSTEHMKESTLEAIGYICQDIDP---E-QLQD-KSNEILTAIIQGMRKEEPSNNVKLAATNALLNSL  202 (876)
T ss_dssp             HHHHHHHHHH-CTTCCHHHHHHHHHHHHHHHHHSCT---T-SSST-THHHHHHHHHHHHCTTCSCHHHHHHHHHHHHHHG
T ss_pred             HHHHHHHHhh-CCCCCHHHHHHHHHHHHHHHHhcCH---H-HHHH-HHHHHHHHHHHHHhCCCCCHHHHHHHHHHHHHHH
Confidence            4566666666 344  56777888888877754221   0 0011 12456677777777665  788888999998887


Q NP_000290.2     624 RH-PLL-H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       624 ~~-~e~-~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      .. ... . ......+++.+...+.+      .++.++..++.+|..+...............+++.+...+.+. ++.+
T Consensus       203 ~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~~~~~~~~~~~~~l~~~l~~~l~~~-~~~v  275 (876)
T 2P8Q_A          203 EFTKANFDKESERHFIMQVVCEATQC------PDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSD-IDEV  275 (876)
T ss_dssp             GGCHHHHTCHHHHHHHHHHHHHHTTC------SSHHHHHHHHHHHHHHHHHCGGGTHHHCCCCCHHHHHHHHTCS-SHHH
T ss_pred             HHchhhccCHHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhcHHHHHHhhhHHHHHHHHHHhcCC-hHHH
Confidence            64 111 1 11122344455555544      3567888899999888764332222112223566666667655 6778


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..+...
T Consensus       276 ~~~a~~~l~~l~~~  289 (876)
T 2P8Q_A          276 ALQGIEFWSNVCDE  289 (876)
T ss_dssp             HHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH
Confidence            88888888777653


No 411
>4I5L_D PP2A A alpha subunit (9-589); EF Hand, Phosphatase, CDC6 (Substrate); HET: FGA, ACB, DAL, MLI, PEG, 1ZN, MAA; 2.43A {Microcystis aeruginosa}
Probab=79.88  E-value=0.12  Score=50.59  Aligned_cols=147  Identities=14%  Similarity=0.094  Sum_probs=80.2  Template_Neff=13.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.+...+. +.++.++..++.++..+......      ..  .....++.+...+.+.++.++..++.++..+....
T Consensus       320 ~~~~~l~~~l~-~~~~~vr~~~~~~l~~l~~~~~~------~~--~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~  390 (584)
T 4I5L_D          320 QILPCIKELVS-DANQHVKSALASVIMGLSPILGK------DN--TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVI  390 (584)
T ss_dssp             CCHHHHHHHHT-CSCHHHHHHHHTTGGGGHHHHHH------HH--CCCCCHHHHHHHHTCSCHHHHHHHHTCCHHHHHHS
T ss_pred             hHHHHHHHHcc-CCCHHHHHHHHHHHHHHHHHhCC------cc--hHHHHHHHHHHHhcCCCHHHHHHHHHcHHHHHHHc
Confidence            45666666776 35667777888888777653211      11  12345666677777777778888888887776541


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      .... ....+++.+...+.+      .+..++..++.++..+....+.   ......+++.+..++.+. ++.++..++.
T Consensus       391 ~~~~-~~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~---~~~~~~~~~~l~~~l~~~-~~~vr~~a~~  459 (584)
T 4I5L_D          391 GIRQ-LSQSLLPAIVELAED------AKWRVRLAIIEYMPLLAGQLGV---EFFDEKLNSLCMAWLVDH-VYAIREAATS  459 (584)
T ss_dssp             CHHH-HHHHHHHHHHHHHTC------SSHHHHHHHHHHHHHHHHHHCH---HHCCCCCHHHHHHHTTCS-SHHHHHHHHH
T ss_pred             ChHH-HHHhHHHHHHHHHHh------CCHHHHHHHHHHHHHHHHhcCh---HHhHHHHHHHHHHHHcCC-HHHHHHHHHH
Confidence            1111 112244445555544      2456666677777666543111   111112344444555444 5556666666


Q NP_000290.2     707 LLSDMWS  713 (747)
Q Consensus       707 aLsnL~~  713 (747)
                      +|..+..
T Consensus       460 ~l~~l~~  466 (584)
T 4I5L_D          460 NLKKLVE  466 (584)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            6666554


No 412
>1QGR_A IMPORTIN BETA SUBUNIT, IMPORTIN ALPHA-2; TRANSPORT RECEPTOR, NUCLEAR IMPORT, HEAT; 2.3A {Homo sapiens} SCOP: a.118.1.1
Probab=79.85  E-value=0.12  Score=54.15  Aligned_cols=154  Identities=11%  Similarity=0.065  Sum_probs=92.3  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsnLa  623 (747)
                      .++.|...+. +.+  +.++..++.+|..++.....   . .... ....+++.+...+.+.+  +.++..++.+|..++
T Consensus       129 ~~~~l~~~l~-~~~~~~~~~~~~l~~l~~l~~~~~~---~-~~~~-~~~~l~~~l~~~l~~~~~~~~vr~~a~~~l~~l~  202 (876)
T 1QGR_A          129 LIPQLVANVT-NPNSTEHMKESTLEAIGYICQDIDP---E-QLQD-KSNEILTAIIQGMRKEEPSNNVKLAATNALLNSL  202 (876)
T ss_pred             HHHHHHHHHc-CCCCCHHHHHHHHHHHHHHHhhCCH---H-HHHH-HHHHHHHHHHHHhcCCCCCHHHHHHHHHHHHHHH
Confidence            4556666666 344  56777888888877754221   0 0111 12356677777777655  788888999998887


Q NP_000290.2     624 RHP-LL-H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       624 ~~~-e~-~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      ... .. . ......+++.+...+.+      .++.++..++.+|..++..............+++.+...+.+. ++.+
T Consensus       203 ~~~~~~~~~~~~~~~i~~~l~~~~~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~l~~~l~~~l~~~-~~~v  275 (876)
T 1QGR_A          203 EFTKANFDKESERHFIMQVVCEATQC------PDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSD-IDEV  275 (876)
T ss_pred             hhCCcccCChHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhCHHHhhHhhHHhHHHHHHHHhCCC-CHHH
Confidence            652 11 1 11122344455555544      3577888899999888765332222111223566666667655 6778


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..++..
T Consensus       276 ~~~a~~~l~~l~~~  289 (876)
T 1QGR_A          276 ALQGIEFWSNVCDE  289 (876)
T ss_pred             HHHHHHHHHHHHHH
Confidence            88888888777654


No 413
>1B3U_A PROTEIN PHOSPHATASE PP2A, 65 KD; SCAFFOLD PROTEIN, PP2A, PHOSPHORYLATION, HEAT; 2.3A {Homo sapiens} SCOP: a.118.1.2
Probab=79.78  E-value=0.12  Score=50.60  Aligned_cols=146  Identities=14%  Similarity=0.095  Sum_probs=76.6  Template_Neff=13.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.+...+. +.++.++..++.++..+......      . . .....++.+...+.+.++.++..++.++..+....
T Consensus       324 ~~~~~l~~~l~-~~~~~vr~~~~~~l~~l~~~~~~------~-~-~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~  394 (588)
T 1B3U_A          324 QILPCIKELVS-DANQHVKSALASVIMGLSPILGK------D-N-TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVI  394 (588)
T ss_dssp             CCHHHHHHHHT-CSCHHHHHHHHTTGGGGHHHHCH------H-H-CCCCCHHHHHHHHTCSCHHHHHHHHTTCHHHHHHS
T ss_pred             hHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHHCc------c-c-hHHhHHHHHHHHhcCCCHHHHHHHHhchHHHHHhc
Confidence            45566666676 35667777888888777653211      1 1 11345666677777777778888888887776541


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      .... ....+++.+...+.+      .+..++..++.++..+....+.   ......+++.+..++.+. +..++..++.
T Consensus       395 ~~~~-~~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~---~~~~~~~~~~l~~~l~~~-~~~vr~~a~~  463 (588)
T 1B3U_A          395 GIRQ-LSQSLLPAIVELAED------AKWRVRLAIIEYMPLLAGQLGV---EFFDEKLNSLCMAWLVDH-VYAIREAATS  463 (588)
T ss_dssp             CHHH-HHHHHHHHHHHHHTC------SSHHHHHHHHHHHHHHHHHHCG---GGCCHHHHHHHHHGGGCS-SHHHHHHHHH
T ss_pred             CHHH-HHHHHHHHHHHHHhc------CCHHHHHHHHHHHHHHHHhcCh---HHhHHHHHHHHHHHhcCC-hHHHHHHHHH
Confidence            1111 111234444444444      2455666666666666542111   111112333444444433 4455555555


Q NP_000290.2     707 LLSDMW  712 (747)
Q Consensus       707 aLsnL~  712 (747)
                      +|..+.
T Consensus       464 ~l~~l~  469 (588)
T 1B3U_A          464 NLKKLV  469 (588)
T ss_dssp             HHHHHH
T ss_pred             HHHHHH
Confidence            555544


No 414
>6MZE_Z Tubulin alpha-1A chain, Tubulin beta; Microtubule, Tubulin, Tubulin polymerization, Heat; HET: MG, GTP, GDP; 3.6A {Sus scrofa}
Probab=79.70  E-value=0.13  Score=50.52  Aligned_cols=152  Identities=11%  Similarity=0.094  Sum_probs=94.5  Template_Neff=12.900

Q NP_000290.2     550 RTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR-LLQSGNSDVVRSGASLLSNMSRHPLL  628 (747)
Q Consensus       550 ~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~-LL~s~d~eVr~~AL~aLsnLa~~~e~  628 (747)
                      +.+...+. +.++.++..++.+|..++..... ........ ....+++.|+. ++.+.++.++..++.+|..+......
T Consensus        57 ~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~-~~~~~~~~-~~~~~l~~l~~~~~~~~~~~vr~~a~~~l~~l~~~~~~  133 (536)
T 6MZE_Z           57 ELFASYIV-DSNVVAQENAIIALHTLLEYISQ-VPNVSTSK-LRLQWIPPLVEKGLSSSRAATKAKATDCIMLLTQSDTS  133 (536)
T ss_dssp             HHHHHHHS-CSSHHHHHHHHHHHHHHHHHTSS-SCCTTHHH-HHHHHHHHHCCCCCSCSCHHHHHHHHHHHHHHHHHSSS
T ss_pred             HHHHHHhc-CchHHHHHHHHHHHHHHHHHhcc-CCCCCcHH-HHHhhHHHHHHhhccCCCHHHHHHHHHHHHHHhccCcc
Confidence            55666676 47788899999999888754211 00000011 12345666776 56667788899999999888764111


Q NP_000290.2     629 HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK---QYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       629 ~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~---~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                          ...+++.+...+.+      .++.++..++.+|..++........   ......+++.+...+.+. ++.++..++
T Consensus       134 ----~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~vr~~a~  202 (536)
T 6MZE_Z          134 ----IQQTVNLMLPSLSN------KLPRLVSSCVKCLATIIEEFGFINVSDINILLSEILEPLPKLSSHA-DRNVRSETM  202 (536)
T ss_dssp             ----SHHHHHHHSGGGGC------SCHHHHHHHHHHHHHHHHTTCSCSCTTHHHHHHHHHTTHHHHHTCS-SHHHHHHHH
T ss_pred             ----HHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhCCCcccccccchHHHHHHHHHHhcCC-CHHHHHHHH
Confidence                11244555555554      3678888899999888764222110   001234567777777766 788999999


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .++..+....
T Consensus       203 ~~l~~l~~~~  212 (536)
T 6MZE_Z          203 NLILQIYKWF  212 (536)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHH
Confidence            9988887543


No 415
>5F0N_A cohesin subunit Pds5, KLTH0D07062p; heat repeat cohesin subunit, cell; 3.2A {Lachancea thermotolerans}
Probab=79.14  E-value=0.17  Score=59.20  Aligned_cols=150  Identities=8%  Similarity=0.095  Sum_probs=100.7  Template_Neff=8.200

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.|...|. +++..+|..|+.+|+.+....+.  .. ...  .....++.++..+.+.++.++..++.++..+....
T Consensus       271 ~vlp~L~~~L~-~~d~~vR~~Av~~Lg~l~~~~~~--~~-l~~--~~~~l~~~ll~rl~D~~~~VR~~av~~L~~i~~~~  344 (1175)
T 5F0N_A          271 SVTGLLYQLLC-SDNELFRESATKCVSKMLGTHSL--IN-FAV--AHSDTYKIWLSKMADISPHVRQAWVSEIPSILMSR  344 (1175)
T ss_dssp             GGHHHHHHHTT-CSSHHHHHHHHHHHHHHHTSCCS--SC-HHH--HTHHHHHHHHGGGSCSCHHHHHHHHTTHHHHHHHC
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHHHccccc--cc-HHH--HcHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHcC
Confidence            36777888887 47788999999999988753210  00 011  12346667777788888999999999999887641


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ..   ....+++.|...+.+      .++.++..++.+|..+.....  .........++.|...+.+. ++.+|..|+.
T Consensus       345 ~~---l~~~ii~~L~~~L~D------~d~~VR~~av~~L~~l~~~~~--~~~~~~~~ll~~L~~~l~D~-~~~VR~~A~~  412 (1175)
T 5F0N_A          345 SD---LSDDISKGLAKALID------SDHTVRLSAIQTFHEVPVKRL--WECLPNAAVFAGLVHLTRET-RRDLRDECID  412 (1175)
T ss_dssp             SS---CHHHHHHHHHHHHTC------SSHHHHHHHHGGGTSSCHHHH--HHHCCCHHHHHHHHTTTTCC-SHHHHHHHHH
T ss_pred             hh---hHHHHHHHHHHHhCC------CCHHHHHHHHHHHHhhhhhhh--hhcCCchHHHHHHHHHHhcC-CHHHHHHHHH
Confidence            11   112355666666766      378899999999988764311  01111134567777777776 7889999999


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      +|+.+...
T Consensus       413 aL~~l~~~  420 (1175)
T 5F0N_A          413 AVARIYTE  420 (1175)
T ss_dssp             HHHHHHHH
T ss_pred             HHHHHHHH
Confidence            98887754


No 416
>4NEE_G AP-2 complex subunit sigma, AP-2; clathrin Adaptor AP-2, HIV-1 Nef; 2.8841A {Rattus norvegicus}
Probab=78.80  E-value=0.15  Score=48.94  Aligned_cols=115  Identities=12%  Similarity=0.097  Sum_probs=71.6  Template_Neff=12.000

Q NP_000290.2     548 AIRTYLNLM--GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL--~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+..++  . +.++.++..++.+|..+....+.        .+....+++.|...+.+.++.++..++.+|..+...
T Consensus       149 ~~~~l~~~l~~~-~~~~~vr~~a~~~L~~l~~~~~~--------~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  219 (398)
T 4NEE_G          149 FAGEIPKILVAG-DTMDSVKQSAALCLLRLYRTSPD--------LVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQK  219 (398)
T ss_dssp             HTTHHHHHHHCS-SSCHHHHHHHHHHHHHHHHHCGG--------GSCCSSHHHHHHGGGGCSCHHHHHHHHHHHHHHHHH
T ss_pred             HHHhHHHHHhcC-CCCHHHHHHHHHHHHHHHHHChh--------hccccchHHHHHHHhcCCCHHHHHHHHHHHHHHHHh
Confidence            455666777  6 46778888999999988764221        111245677788888777888999999999988865


Q NP_000290.2     626 PL-LHRVMGNQVFPEVTRLLTSHTG-------NTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       626 ~e-~~~ll~~giI~~Ll~LL~s~s~-------~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                      .. ........+++.+..++.+...       ....++.++..++.+|..+...
T Consensus       220 ~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~~~~~  273 (398)
T 4NEE_G          220 NPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPP  273 (398)
T ss_dssp             CGGGGTHHHHHHHHHHHHHHHCCTTTTGGGEETTEESHHHHHHHHHHHTTSCSC
T ss_pred             CHHHHHHHHHHHHHHHHHHHhcCCcCcccccccCCCCHHHHHHHHHHHHhCCCC
Confidence            21 1111112345555555543000       0001456777888888887754


No 417
>3W3U_A Importin subunit beta-3; HEAT repeat, nuclear import, PROTEIN; 2.6A {Saccharomyces cerevisiae}
Probab=78.75  E-value=0.14  Score=55.16  Aligned_cols=158  Identities=8%  Similarity=0.034  Sum_probs=93.7  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....     ..... ...+++.|...+.+.++.++..++.+|+.++....
T Consensus       849 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  921 (1078)
T 3W3U_A          849 IWPMINTFLL-DNEPILVIFALVVIGDLIQYGGE-----QTASM-KNAFIPKVTECLISPDARIRQAASYIIGVCAQYAP  921 (1078)
T ss_dssp             GHHHHHHHHT-SSCHHHHHHHHHHHHHHHHHHGG-----GCHHH-HHHHHHHHHHHHTCSCHHHHHHHHHHHHHHHHHSC
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhcch-----hhHHH-HHhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHCc
Confidence            3444555555 35667777888888887754221     01111 23567777888888888999999999999887621


Q NP_000290.2     628 -LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       628 -~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                       ........+++.|...+.........+..++..++.+|..+....+....  ....+++.++..+....++.++..++.
T Consensus       922 ~~~~~~~~~~l~~l~~~l~~~~~~~~~~~~vr~~a~~~l~~l~~~~~~~~~--~~~~~~~~l~~~l~~~~~~~~~~~~~~  999 (1078)
T 3W3U_A          922 STYADVCIPTLDTLVQIVDFPGSKLEENRSSTENASAAIAKILYAYNSNIP--NVDTYTANWFKTLPTITDKEAASFNYQ  999 (1078)
T ss_dssp             TTTHHHHHHHHHHHHHHTC-CCTTSHHHHHHHHHHHHHHHHHHHHC--------CCHHHHHHHTTCCCCSCHHHHHHHHH
T ss_pred             cccHHhHHHHHHHHHHHHhCCCcccccccchHHHHHHHHHHHHHHcccCCC--ChhHHHHHHHHhCCcCCCHHHHHHHHH
Confidence             11111134566666666510000003678899999999998875332211  122456666666632226677888888


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      +|..++..
T Consensus      1000 ~l~~l~~~ 1007 (1078)
T 3W3U_A         1000 FLSQLIEN 1007 (1078)
T ss_dssp             HHHHHHHT
T ss_pred             HHHHHHHc
Confidence            88877754


No 418
>4NEE_B AP-2 complex subunit sigma, AP-2; clathrin Adaptor AP-2, HIV-1 Nef; 2.8841A {Rattus norvegicus}
Probab=78.75  E-value=0.15  Score=49.03  Aligned_cols=115  Identities=12%  Similarity=0.097  Sum_probs=71.5  Template_Neff=11.900

Q NP_000290.2     548 AIRTYLNLM--GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL--~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+..++  . +.++.++..++.+|..+....+.        .+....+++.|...+.+.++.++..++.+|..+...
T Consensus       149 ~~~~l~~~l~~~-~~~~~vr~~a~~~L~~l~~~~~~--------~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  219 (398)
T 4NEE_B          149 FAGEIPKILVAG-DTMDSVKQSAALCLLRLYRTSPD--------LVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQK  219 (398)
T ss_pred             HHHHHHHHHcCC-CCCHHHHHHHHHHHHHHHHHChh--------HhcHhhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHh
Confidence            455666777  6 46778888999999988764221        111245677788888777888999999999988865


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTG-------NTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~-------~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                      ... .......+++.+..++.+...       ....++.++..++.+|..+...
T Consensus       220 ~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~~~~~  273 (398)
T 4NEE_B          220 NPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPP  273 (398)
T ss_pred             CHHHhHHHHHHHHHHHHHHHcCCCCCCccccccCCCCHHHHHHHHHHHHhhccC
Confidence            211 111112345555555543000       0001456777888888887754


No 419
>3DAD_A FH1/FH2 domain-containing protein 1; Formin, FHOD1, GTPase-binding domain, ubiquitin-superfold; 2.3A {Homo sapiens}
Probab=78.49  E-value=0.18  Score=50.49  Aligned_cols=154  Identities=13%  Similarity=0.081  Sum_probs=94.1  Template_Neff=8.200

Q NP_000290.2     565 LEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVM-GNQVFPEVTR  642 (747)
Q Consensus       565 r~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll-~~giI~~Ll~  642 (747)
                      ...++..|..++.....     ....|++.+++..|+.++...+......++.+|..|...... ..++ ....+..|..
T Consensus       135 l~~~L~~L~~~l~~d~~-----wv~eFi~~~Gl~~L~~~l~~~~~~~~~~~L~cl~~Lm~~~~G~~~v~~~~~~i~~l~~  209 (339)
T 3DAD_A          135 LRRSLFSLKQIFQEDKD-----LVPEFVHSEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSDTIQWLYT  209 (339)
T ss_dssp             HHHHHHHHHHHHHTCTT-----HHHHHHHTTHHHHHHHHHTTSCHHHHHHHHHHHHHHTTSHHHHHHHHHCHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhCCcc-----HHHHHHHCCHHHHHHHHHHHccHHHHHHHHHHHHHHHhCHHHHHHHHhCHHHHHHHHH
Confidence            34566666666521121     345557788999999999876666777888888888776222 2222 2346677777


Q NP_000290.2     643 LLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFS----------SSMLNNIINLCRSS--ASPKAAEAARLLLSD  710 (747)
Q Consensus       643 LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve----------~giL~~Ll~LL~s~--~d~eVr~aAL~aLsn  710 (747)
                      .+.+      ....++..++.+|..++...+.....+.+          ...+..++..+...  .+.+++..++.++..
T Consensus       210 ~l~s------~~~~v~~~al~iL~~l~~~~~~g~~~Vl~al~~~~~~~~~~~f~~lv~~L~~~~~~d~e~~~~~L~LINa  283 (339)
T 3DAD_A          210 LCAS------LSRLVVKTALKLLLVFVEYSENNAPLFIRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTVTLINK  283 (339)
T ss_dssp             GGGC------SCHHHHHHHHHHHHHHHHHCGGGHHHHHHHHHHHHHHHCCCTTHHHHHHHTTTTSCCHHHHHHHHHHHHH
T ss_pred             HhcC------CCHHHHHHHHHHHHHHHhcCCCcHHHHHHHHHhHHHhhCCCCHHHHHHHHHhhCCCCHHHHHHHHHHHHH
Confidence            7765      35678888888888887654333222222          23466677777642  156677777777777


Q NP_000290.2     711 MWSSKE-------LQGVLRQQGFDRN  729 (747)
Q Consensus       711 L~~~~~-------~~~~~~~~~~~~~  729 (747)
                      |+....       +..-|.+.|+..-
T Consensus       284 Ll~~~~d~~~R~~lr~~L~~~Gi~~i  309 (339)
T 3DAD_A          284 TLAALPDQDSFYDVTDALEQQGMEAL  309 (339)
T ss_dssp             HHHHCSSHHHHHHHHHHHHHTTHHHH
T ss_pred             HHHcCCCHHHHHHHHHHHHHCChHHH
Confidence            664433       3344555665443


No 420
>5VJC_A Protein mini spindles; TOG, HEAT Repeat, Tubulin, CELL; 2.0A {Drosophila melanogaster}
Probab=78.36  E-value=0.16  Score=46.47  Aligned_cols=73  Identities=11%  Similarity=0.004  Sum_probs=44.8  Template_Neff=11.400

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ....+.+...+. +.++.++..++..|..++.....     ..... -..++..+...+.+.++.++..++.++..++..
T Consensus        49 ~~~~~~l~~~l~-~~~~~~r~~a~~~L~~~~~~~~~-----~~~~~-~~~l~~~l~~~l~d~~~~v~~~a~~~l~~l~~~  121 (271)
T 5VJC_A           49 ANVNKALIANMF-HDDFRYHLKVIEQLSEDLAGNSK-----ALVCN-LDLILKWLTLRFYDTNPSVLIKGLEYLVQVFQV  121 (271)
T ss_dssp             TTCCHHHHHHHT-CSSHHHHHHHHHHHHHHTTTCHH-----HHHHT-HHHHHHHHHHHTSSCCHHHHHHHHHHHHHHHHH
T ss_pred             hcCCHHHHHhcc-CCCHHHHHHHHHHHHHHHhcChH-----HHHHH-HHHHHHHHHHHHhCCCHHHHHHHHHHHHHHHHH
Confidence            334566777776 46778888888888888764321     01111 123344444555566777888888888877654


No 421
>5WBJ_A Regulatory-associated protein of TOR 1,Eukaryotic; Raptor, TOS, PROTEIN BINDING; 3.0A {Arabidopsis thaliana}
Probab=78.29  E-value=0.18  Score=59.27  Aligned_cols=156  Identities=10%  Similarity=0.095  Sum_probs=112.5  Template_Neff=8.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      .++.+++.|.+   +..+..|+..|..++.....     ....+...++++.++.+|.+..++++..++.++++++.. +
T Consensus       467 qLp~~lq~L~s---~~~r~rAL~~L~~~ld~~~~-----~~~~~~~~gi~p~ll~lL~s~~~~lr~~a~~i~a~i~~~d~  538 (1287)
T 5WBJ_A          467 QLPIVLQVLLS---QCHRFRALVLLGRFLDMGSW-----AVDLALSVGIFPYVLKLLQTTTNELRQILVFIWTKILALDK  538 (1287)
T ss_dssp             CHHHHHHHTTS---STTHHHHHHHHHHHHTTCHH-----HHHHHHHHTCHHHHHHGGGCCCHHHHHHHHHHHHHHHHHCG
T ss_pred             HHHHHHHHHcC---HHHHHHHHHHHHHHHhcCHH-----HHHHHHHCCcHHHHHHHHcCCCHHHHHHHHHHHHHHHccCH
Confidence            46666777752   23677899999998874332     234445679999999999988889999999999999876 3


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR-------SSASP  698 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~-------s~~d~  698 (747)
                      .. ..++..+.+..|+.+|....    ..+.++..++.+|+.++...+.....+...+++..+...+.       +. ++
T Consensus       539 ~~q~~l~~~~~l~~ll~~L~~~~----~~~~~r~~a~~~Ls~l~~~~~~~~~~~~~~~~l~~l~~~L~~~~~~~~~~-~~  613 (1287)
T 5WBJ_A          539 SCQIDLVKDGGHTYFIRFLDSSG----AFPEQRAMAAFVLAVIVDGHRRGQEACLEANLIGVCLGHLEASRPSDPQP-EP  613 (1287)
T ss_dssp             GGHHHHHHTTCHHHHHHHHHCSS----CCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHCC----------CH
T ss_pred             HHHHHHHHcCCeeeEEEeecCCC----CCHHHHHHHHHHHHHHHcCCHhHHHHHHHCcHHHHHHHHHHhcCCCCCCC-CH
Confidence            33 34455667888888886420    23556778899999998765555555555577788877776       34 67


Q NP_000290.2     699 KAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       699 eVr~aAL~aLsnL~~~~~  716 (747)
                      .++..++.+|..|+...+
T Consensus       614 ~lr~~a~~~L~~L~~~~~  631 (1287)
T 5WBJ_A          614 LFLQWLCLCLGKLWEDFM  631 (1287)
T ss_dssp             HHHHHHHHHHHHHHTTCH
T ss_pred             HHHHHHHHHHHHHHhccH
Confidence            889999999999986654


No 422
>5WBK_A Regulatory-associated protein of TOR 1,Ribosomal; Raptor, TOS, PROTEIN BINDING; 3.11A {Arabidopsis thaliana}
Probab=78.26  E-value=0.18  Score=59.26  Aligned_cols=156  Identities=10%  Similarity=0.095  Sum_probs=112.8  Template_Neff=8.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      .++.+++.|.+   +..+..|+..|..++.....     ....+...++++.|+.+|.+..++++..++.++++++.. +
T Consensus       467 ~Lp~~lq~L~s---~~~r~rAL~~L~~~ld~~~~-----a~~~~l~~Gi~p~ll~lL~s~~~~lr~~a~~i~a~i~~~d~  538 (1287)
T 5WBK_A          467 QLPIVLQVLLS---QCHRFRALVLLGRFLDMGSW-----AVDLALSVGIFPYVLKLLQTTTNELRQILVFIWTKILALDK  538 (1287)
T ss_dssp             SHHHHHHHHTS---GGGHHHHHHHHHHHHTTCHH-----HHHHHHHHTCHHHHHHGGGCCCHHHHHHHHHHHHHHHHHCG
T ss_pred             HHHHHHHHHcC---HHHHHHHHHHHHHHHhcCHH-----HHHHHHHCCcHHHHHHHHcCCCHHHHHHHHHHHHHHHccCH
Confidence            46666777752   23677899999998874332     233445679999999999988889999999999999876 3


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR-------SSASP  698 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~-------s~~d~  698 (747)
                      .. ..++..+.+..|+.+|....    ..+.++..++.+|+.++...+.....+.+.+++..+...|.       +. ++
T Consensus       539 ~~q~~l~~~~~l~~ll~~L~~~~----~~~~~r~~a~~~Ls~l~~~~~~~~~~~~~~~~l~~l~~~L~~~~~~~~~~-~~  613 (1287)
T 5WBK_A          539 SCQIDLVKDGGHTYFIRFLDSSG----AFPEQRAMAAFVLAVIVDGHRRGQEACLEANLIGVCLGHLEASRPSDPQP-EP  613 (1287)
T ss_dssp             GGHHHHHHTTTHHHHHHHHHSSC----CCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHCC----------CH
T ss_pred             HHHHHHHHcCCeeeEEEeecCCC----CCHHHHHHHHHHHHHHHcCCHhHHHHHHHCcHHHHHHHHHHhcCCCCCCC-CH
Confidence            33 34455667788888886420    23556778889999998765555555555577888877776       34 68


Q NP_000290.2     699 KAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       699 eVr~aAL~aLsnL~~~~~  716 (747)
                      .++..++.+|..|+....
T Consensus       614 ~lr~~a~~~L~~L~~~~~  631 (1287)
T 5WBK_A          614 LFLQWLCLCLGKLWEDFM  631 (1287)
T ss_dssp             HHHHHHHHHHHHHHTTCH
T ss_pred             HHHHHHHHHHHHHHcccH
Confidence            889999999999986654


No 423
>6EN4_C Splicing factor 3B subunit 3; Protein complex, splicing modulator, SPLICING; HET: BGZ; 3.08A {Homo sapiens}
Probab=78.21  E-value=0.15  Score=53.32  Aligned_cols=154  Identities=10%  Similarity=0.027  Sum_probs=92.8  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKK-DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d-~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .++.+...+.+ .+ +.++..++.+|..+....+.     .... .-..+++.+...+.+.++.++..++.++..+....
T Consensus       192 ~~~~l~~~l~~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~i~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~  264 (852)
T 6EN4_C          192 LLPFLKAVCKS-KKSWQARHTGIKIVQQIAILMGC-----AILP-HLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAA  264 (852)
T ss_pred             HHHHHHHHHcC-CCCHHHHHHHHHHHHHHHhhCch-----hhcc-cHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHHcC
Confidence            34445555552 33 67888888888888754321     1111 12345677777777778889999999998887652


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. .......+++.+...+.+      ....++..++.+|..++...+..........+++.+...+.+. ++.++..++
T Consensus       265 ~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~vr~~a~  337 (852)
T 6EN4_C          265 TPYGIESFDSVLKPLWKGIRQ------HRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSP-DEEMKKIVL  337 (852)
T ss_pred             CHHHHHHHHHHHHHHHHHHhc------CCHHHHHHHHHHHHHHHhcCCHHHhHHHHHHHHHHHHHHhcCC-CHHHHHHHH
Confidence            11 111112345666666654      2456777888888887764222111111124566666666655 677888888


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .++..++...
T Consensus       338 ~~l~~l~~~~  347 (852)
T 6EN4_C          338 KVVKQCCGTD  347 (852)
T ss_pred             HHHHHHhhcC
Confidence            8888877543


No 424
>5F0O_A cohesin subunit Pds5, KLTH0D07062p, KLTH0G16610p; heat repeat cohesin subunit, cell; 3.5A {Lachancea thermotolerans}
Probab=78.20  E-value=0.18  Score=58.49  Aligned_cols=150  Identities=8%  Similarity=0.096  Sum_probs=99.5  Template_Neff=8.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.|...|. +.++.+|..|+.+|+.+......  .. ....  ....++.++..+.+.++.++..++.++..+....
T Consensus       280 ~vlp~L~~~L~-~~d~~vR~~Av~~Lg~l~~~~~~--~~-l~~~--~~~l~~~ll~rl~D~~~~VR~~av~~l~~i~~~~  353 (1133)
T 5F0O_A          280 SVTGLLYQLLC-SDNELFRESATKCVSKMLGTHSL--IN-FAVA--HSDTYKIWLSKMADISPHVRQAWVSEIPSILMSR  353 (1133)
T ss_dssp             TSTTTTTTTTS-CSSHHHHHHHHHHHHHHHHSCCS--ST-TTTT--THHHHHHHHHTTSCSCHHHHHHHTTSHHHHHTTC
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHHHccccc--cc-HHHH--cHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHhcC
Confidence            35677778887 47788899999999998653210  00 0111  1345666777778888999999999998887641


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ..   ....+++.|...+.+      .++.++..++.+|+.+.....  .........++.|...+.+. ++.+|..|+.
T Consensus       354 ~~---l~~~ii~~L~~~L~D------~d~~VR~~av~~L~~l~~~~~--~~~~~~~~ll~~L~~~l~D~-~~~VR~~A~~  421 (1133)
T 5F0O_A          354 SD---LSDDISKGLAKALID------SDHTVRLSAIQTFHEVPVKRL--WECLPNAAVFAGLVHLTRET-RRDLRDECID  421 (1133)
T ss_dssp             ST---THHHHHHHHHHTTSC------SSHHHHHHHHTHHHHSCHHHH--HHHCCCHHHHHHHHHGGGBS-SHHHHHHHHH
T ss_pred             hh---HHHHHHHHHHHHhCC------CCHHHHHHHHHHHhhcchhcH--hhcCCchHHHHHHHHHHhcC-CHHHHHHHHH
Confidence            11   112355666666766      478899999999988764311  01111134567777777766 7888999999


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      +|+.+...
T Consensus       422 aL~~l~~~  429 (1133)
T 5F0O_A          422 AVARIYTE  429 (1133)
T ss_dssp             HHHHHHHH
T ss_pred             HHHHHHHH
Confidence            88887754


No 425
>2NYL_A Protein phosphatase 2, regulatory subunit; HEAT repeat, HYDROLASE-HYDROLASE INHIBITOR COMPLEX; HET: DAL, MSE, ACB, 1ZN, DAM, FGA; 3.8A {Homo sapiens} SCOP: a.118.1.2
Probab=77.79  E-value=0.16  Score=49.54  Aligned_cols=109  Identities=15%  Similarity=0.189  Sum_probs=67.0  Template_Neff=13.500

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      ..++.+...+. +.++.++..++.++..+......       .. ....+++.+...+.+.++.++..++.++..+... 
T Consensus       236 ~~~~~l~~~l~-~~~~~vr~~~~~~l~~~~~~~~~-------~~-~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~~~~~~  306 (582)
T 2NYL_A          236 LVMPTLRQAAE-DKSWRVRYMVADKFTELQKAVGP-------EI-TKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENL  306 (582)
T ss_dssp             TTHHHHHHHHH-CSSHHHHHHHHHTHHHHHHHHCS-------HH-CCCCCHHHHHHHHTCSSHHHHHHHHTTHHHHHHTS
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHhHHHHHHHHCC-------CC-CHhhhHHHHHHHhcCChHHHHHHHHHHHHHHHHhC
Confidence            35566666676 46777888888888887754221       11 1245667777777777788888999998888764 


Q NP_000290.2     626 PLL-H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       626 ~e~-~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      ... . ......+++.+...+.+      .++.++..++.++..+..
T Consensus       307 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~~~~~l~~l~~  347 (582)
T 2NYL_A          307 SADCRENVIMSQILPCIKELVSD------ANQHVKSALASVIMGLSP  347 (582)
T ss_dssp             CTTTHHHHCCCCCHHHHHHHHTC------SCHHHHHHHHHHGGGGHH
T ss_pred             CCcchHHHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHH
Confidence            111 1 11112345555555554      245666667777666654


No 426
>3W3W_A Importin subunit beta-3, Protein STE12; HEAT repeat, nuclear import, PROTEIN; 2.2A {Saccharomyces cerevisiae}
Probab=77.60  E-value=0.16  Score=54.65  Aligned_cols=157  Identities=9%  Similarity=0.079  Sum_probs=90.3  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      +++.+...+. +.++.++..++.+|..++...+.     .... ....+++.|...+.+.++.++..++.+|+.++.. +
T Consensus       849 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  921 (1078)
T 3W3W_A          849 IWPMINTFLL-DNEPILVIFALVVIGDLIQYGGE-----QTAS-MKNAFIPKVTECLISPDARIRQAASYIIGVCAQYAP  921 (1078)
T ss_dssp             GHHHHHHHHC---CHHHHHHHHHHHHHHHTC--C-----CCHH-HHHHHHHHHHHHHTCSCHHHHHHHHHHHHHHHHHSS
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhcch-----hhHH-HHHhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHCc
Confidence            3445555555 35667777888888888764221     1111 1245677778888888889999999999999876 2


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. ...+ ..+++.+...+.........+..++..++.+|..+....+....  ....+++.++..+....+..++..++
T Consensus       922 ~~~~~~~-~~~l~~l~~~l~~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~--~~~~~~~~l~~~l~~~~~~~~~~~~~  998 (1078)
T 3W3W_A          922 STYADVC-IPTLDTLVQIVDFPGSKLEENRSSTENASAAIAKILYAYNSNIP--NVDTYTANWFKTLPTITDKEAASFNY  998 (1078)
T ss_dssp             TTTHHHH-HHHHHHHHHHTC--CCSSGGGHHHHHHHHHHHHHHHHHTTTSCC----CHHHHHHHTTCCCCSCHHHHHHHH
T ss_pred             cchHhhH-HHHHHHHHHHHhCCCCcchhchhhHHHHHHHHHHHHHHcccCCC--chhHHHHHHHHhCCccCCHHHHHHHH
Confidence            21 1112 34666677766521000003567888899999988765332111  12235566666664222567788888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..+...
T Consensus       999 ~~l~~l~~~ 1007 (1078)
T 3W3W_A          999 QFLSQLIEN 1007 (1078)
T ss_dssp             HHHHC----
T ss_pred             HHHHHHHHc
Confidence            888777654


No 427
>4LAC_A Serine/threonine-protein phosphatase 2A activator (E.C.5.2.1.8); PP2A, PTPA, protein phosphatase, signaling; HET: AGS, MES; 2.82A {Homo sapiens}
Probab=77.52  E-value=0.17  Score=44.16  Aligned_cols=115  Identities=13%  Similarity=-0.025  Sum_probs=73.8  Template_Neff=12.800

Q NP_000290.2     239 DIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS  318 (747)
Q Consensus       239 ~~~~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~  318 (747)
                      ........++.+...+.+.++.++..++..+..+.......   .....+++.+...+.+.++.++..++.++..+....
T Consensus        27 ~~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~---~~~~~~~~~l~~~l~~~~~~vr~~~~~~l~~~~~~~  103 (258)
T 4LAC_A           27 CESMSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVE---RTRSELLPFIVELAEDAKWRVRLAIIEYMPLLAGQL  103 (258)
T ss_pred             CCCccccHHHHHHHHhcCCCHHHHHHHHHHHHHHHHccCHH---HHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHhC
Confidence            33334456666777777777888888888888877543211   112345566666676777788888888888776543


Q NP_000290.2     319 TTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       319 ~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ..   ......+++.+...+. +.++.++..++.++..+...
T Consensus       104 ~~---~~~~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~  141 (258)
T 4LAC_A          104 GV---EYFDEKLNSLCMAWLV-DHVYAIREAATSNLKKLVEK  141 (258)
T ss_pred             CC---hHHHHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHc
Confidence            22   1112245556666665 55677888888888887754


No 428
>6FT5_A A3_A3; alphaRep, artificial protein, chimera, bidomain; HET: GOL, SO4; 1.94A {synthetic construct}
Probab=77.46  E-value=0.17  Score=47.66  Aligned_cols=60  Identities=17%  Similarity=0.244  Sum_probs=30.0  Template_Neff=12.800

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      ..++.+...+. +.++.++..++.+|..+...                ..++.+...+.+.++.++..++.++..+.
T Consensus        54 ~~~~~l~~~l~-~~~~~vr~~a~~~L~~~~~~----------------~~~~~l~~~l~~~~~~vr~~a~~~l~~~~  113 (409)
T 6FT5_A           54 RAVEPLIKALK-DEDAWVRRAAADALGQIGDE----------------RAVEPLIKALKDEDGWVRQSAAVALGQIG  113 (409)
T ss_pred             chHHHHHHHhc-CCCHHHHHHHHHHHHHHcCc----------------hhHHHHHHHhcCCCHHHHHHHHHHHHhhC
Confidence            34455555555 34555555666655554321                12233444444555556666666555544


No 429
>1F59_B IMPORTIN BETA-1/FXFG NUCLEOPORIN; Protein-protein complex, TRANSPORT PROTEIN RECEPTOR; 2.8A {Homo sapiens} SCOP: a.118.1.1
Probab=77.42  E-value=0.17  Score=48.11  Aligned_cols=158  Identities=12%  Similarity=0.047  Sum_probs=88.7  Template_Neff=12.900

Q NP_000290.2     547 DAIRTYLNLMGKS-KKDATLEACAGALQNLTASKGLMSS-------GMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASL  618 (747)
Q Consensus       547 G~I~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s~~~s~-------~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~a  618 (747)
                      +.+..++.++.+. .++.++..|+.+|.++...... ..       ......-....+++.|+..+.+.... +..++.+
T Consensus        35 ~~~~~l~~~l~~~~~~~~~r~~a~~~l~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~l~~~l~~~l~~~~~~-r~~~~~~  112 (442)
T 1F59_B           35 TFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDP-DIKAQYQQRWLAIDANARREVKNYVLHTLGTETYR-PSSASQC  112 (442)
T ss_dssp             HHHHHHHHHTTCTTSCHHHHHHHHHHHHTTTCCSSH-HHHHHHHHHHHTSCHHHHHHHHHHHHHHTTCCSSS-SCHHHHH
T ss_pred             HHHHHHHHHHhCCCCCHHHHHHHHHHHHHHhhcCCH-HHHHHHHHHHhhCCHHHHHHHHHHHHHHHCCCCCc-hhHHHHH
Confidence            4556667776521 3566777788888887643110 00       00000001234555566666544333 7778888


Q NP_000290.2     619 LSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNS--EDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA  696 (747)
Q Consensus       619 LsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d--~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~  696 (747)
                      ++.++...... .....+++.+...+.+      .+  +.++..++.+|..+...............+++.+..++.+. 
T Consensus       113 l~~l~~~~~~~-~~~~~~~~~l~~~l~~------~~~~~~~~~~~l~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-  184 (442)
T 1F59_B          113 VAGIACAEIPV-NQWPELIPQLVANVTN------PNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKE-  184 (442)
T ss_dssp             HHHHHHHHGGG-TCCTTHHHHHHHHHHC------TTCCHHHHHHHHHHHHHHHHHSCGGGGGGGHHHHHHHHHHTTSTT-
T ss_pred             HHHHHHhcCCc-chhchHHHHHHHHhhC------CCCcHHHHHHHHHHHHHHHhhCCHHHhHHHHHHHHHHHHHHHhcC-
Confidence            88777541110 0112356666666665      23  67888888998888764221111111124566777777655 


Q NP_000290.2     697 S--PKAAEAARLLLSDMWSS  714 (747)
Q Consensus       697 d--~eVr~aAL~aLsnL~~~  714 (747)
                      +  ..++..++.++..++..
T Consensus       185 ~~~~~vr~~a~~~l~~l~~~  204 (442)
T 1F59_B          185 EPSNNVKLAATNALLNSLEF  204 (442)
T ss_dssp             CCCHHHHHHHHHHHHHHSTT
T ss_pred             CCCHHHHHHHHHHHHHHHHH
Confidence            4  78889999988888654


No 430
>2NYL_A Protein phosphatase 2, regulatory subunit; HEAT repeat, HYDROLASE-HYDROLASE INHIBITOR COMPLEX; HET: DAL, MSE, ACB, 1ZN, DAM, FGA; 3.8A {Homo sapiens} SCOP: a.118.1.2
Probab=77.33  E-value=0.16  Score=49.36  Aligned_cols=70  Identities=17%  Similarity=0.113  Sum_probs=41.5  Template_Neff=13.500

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ..++.+...+. +.++.++..++.++..+......      . . .....++.+...+.+.++.++..++.++..+...
T Consensus       318 ~~~~~l~~~l~-~~~~~vr~~~~~~l~~l~~~~~~------~-~-~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~  387 (582)
T 2NYL_A          318 QILPCIKELVS-DANQHVKSALASVIMGLSPILGK------D-N-TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEV  387 (582)
T ss_dssp             CCHHHHHHHHT-CSCHHHHHHHHHHGGGGHHHHHH------H-H-CCCCCHHHHHHHHHCSSHHHHHHHHTTHHHHTTT
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHhCC------c-c-chhhHHHHHHHHhcCCCHHHHHHHHHhHHHHHHh
Confidence            34556666666 35666777777777776653211      1 1 1134556666666666667777777777766643


No 431
>5FVM_B SERINE/THREONINE-PROTEIN KINASE TOR2, TARGET OF; TRANSFERASE, CRYO-EM, TOR, LST8, MTOR; 6.7A {KLUYVEROMYCES MARXIANUS}
Probab=77.24  E-value=0.18  Score=61.64  Aligned_cols=71  Identities=11%  Similarity=0.111  Sum_probs=39.6  Template_Neff=11.500

Q NP_000290.2     548 AIRTYLNLMGKSKKD-ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~-eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ++..+..++.. ... .++..++.++..++.....     ....+ -..+++.+...+.+.++.++..++.+|..++..
T Consensus       925 ~~~~l~~~l~~-~~~~~~~~~~~~~l~~i~~~~~~-----~~~~~-l~~l~~~l~~~l~~~~~~vr~~a~~~L~~l~~~  996 (2471)
T 5FVM_B          925 VIGVLMKILKD-PSLSIHHSTVIQAIMHIFQTMGL-----RCVIF-LKQIIPGFILVMHTCPPSLLELYFQQLSVLISI  996 (2471)
T ss_dssp             HHHHHHHHHHC----CCHHHHHHHHHHHHHHHC-----------C-HHHHHHHHHHHHC--CHHHHHHHHHHHHHHTTS
T ss_pred             HHHHHHHHHcC-ccchHHHHHHHHHHHHHHHHccc-----hhHHH-HhHHHHHHHHHHhhCCHHHHHHHHHHHHHHHHH
Confidence            34556666652 322 2666777788777653221     01111 134566677777766778888888888888764


No 432
>3LTJ_A AlphaRep-4; protein engineering, HEAT-like repeat, PROTEIN; 1.8A {synthetic}
Probab=77.21  E-value=0.18  Score=42.73  Aligned_cols=121  Identities=12%  Similarity=0.121  Sum_probs=68.3  Template_Neff=12.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..+...                ..++.+...+.+.++.++..++.++..+...  
T Consensus        77 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~----------------~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~--  137 (201)
T 3LTJ_A           77 AVEPLIKALK-DEDGWVRQSAAVALGQIGDE----------------RAVEPLIKALKDEDWFVRIAAAFALGEIGDE--  137 (201)
T ss_dssp             GHHHHHHHTT-CSSHHHHHHHHHHHHHHCCG----------------GGHHHHHHHTTCSSHHHHHHHHHHHHHHTCG--
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHhCCH----------------HHHHHHHHHHhCCCHHHHHHHHHHHHHHCCH--
Confidence            3445555565 35566666666666655421                1233444555566667777777776665431  


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                             ..++.+...+.+      .++.++..++.++..+...           .....+..++.+. ++.++..++.+
T Consensus       138 -------~~~~~l~~~l~~------~~~~v~~~a~~~l~~~~~~-----------~~~~~l~~~~~~~-~~~vr~~a~~~  192 (201)
T 3LTJ_A          138 -------RAVEPLIKALKD------EDGWVRQSAADALGEIGGE-----------RVRAAMEKLAETG-TGFARKVAVNY  192 (201)
T ss_dssp             -------GGHHHHHHHTTC------SSHHHHHHHHHHHHHHCSH-----------HHHHHHHHHHHHC-CHHHHHHHHHH
T ss_pred             -------HHHHHHHHHHhC------CChHHHHHHHHHHHHhCcH-----------HHHHHHHHHHHcC-CHHHHHHHHHH
Confidence                   133444455544      2456677777777665431           2334455555555 67778888877


Q NP_000290.2     708 LSDMW  712 (747)
Q Consensus       708 LsnL~  712 (747)
                      |.++.
T Consensus       193 l~~~~  197 (201)
T 3LTJ_A          193 LETHK  197 (201)
T ss_dssp             HHHCC
T ss_pred             HHhhh
Confidence            77654


No 433
>5JO8_A CEP104; centriolar protein, TOG domain, CEP104; 1.4A {Gallus gallus}
Probab=77.19  E-value=0.18  Score=46.55  Aligned_cols=155  Identities=14%  Similarity=0.100  Sum_probs=90.5  Template_Neff=11.100

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLM---SSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~---s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      .++.+...+. +.++.++..++.++..++......   ... .... .-..+++.|+..+.+.+..++..+..+|..++.
T Consensus        87 l~~~l~~~l~-d~~~~v~~~a~~~l~~l~~~~~~~~~~~~~-~~~~-~~~~~l~~ll~~l~d~~~~vr~~a~~~l~~l~~  163 (279)
T 5JO8_A           87 AIFLVRRAIK-DIVSSVFQASLKLLKMIITQYVPKHKLGKL-ETSH-CVEKTLPGLLSRTGDSSSRLRIVAAKFIQEMAL  163 (279)
T ss_dssp             HHHHHHHHTT-CSSHHHHHHHHHHHHHCCCCCHHHHTCCHH-HHHH-HHHHHHHHHHHHTTCSSHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHcC-CCHHHHHHHHHHHHHHHHHHhcccccCChH-HHHH-HHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHc
Confidence            3445555666 466778888888888877542000   000 0111 113466777777777778888999999888875


Q NP_000290.2     625 HPLLHRVMGNQVFP-EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       625 ~~e~~~ll~~giI~-~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                      .....   ...++. .+...+...     .++.++..++.+|..++..............+++.+...+.+. ++.++..
T Consensus       164 ~~~~~---~~~~~~~~l~~~l~~~-----~~~~~r~~~l~~l~~l~~~~~~~~~~~~~~~i~~~l~~~l~d~-~~~VR~~  234 (279)
T 5JO8_A          164 WSEVK---PLQIVPVHLVQLLKPN-----SPTHLAMSRVELVECLLKEMGTENSGFTISNVMKFATGALEHR-VYEVRDV  234 (279)
T ss_dssp             STTTG---GGCCHHHHHTSCCCTT-----SCHHHHHHHHHHHHHHHHHHCSSSSSCCHHHHHHHHHHHTTCS-CHHHHHH
T ss_pred             CCCCC---hhHhHHHHHhhcCCCC-----CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHhcCC-CHHHHHH
Confidence            42110   011222 222333331     1566777888888887764322211111224567777777766 8899999


Q NP_000290.2     704 ARLLLSDMWSS  714 (747)
Q Consensus       704 AL~aLsnL~~~  714 (747)
                      +..++..+...
T Consensus       235 a~~~l~~l~~~  245 (279)
T 5JO8_A          235 ALRIIFGMYRK  245 (279)
T ss_dssp             HHHHHHHHHHH
T ss_pred             HHHHHHHHHHH
Confidence            99988887643


No 434
>4P6Z_G BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=77.19  E-value=0.18  Score=51.67  Aligned_cols=101  Identities=12%  Similarity=0.040  Sum_probs=52.0  Template_Neff=12.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++..+..+....       ....+++.+...+.+.++.++..++.++..+....+...   
T Consensus       117 ~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~-------~~~~~~~~l~~~l~~~~~~vr~~a~~~L~~l~~~~~~~~---  186 (627)
T 4P6Z_G          117 MTNCIKNDLNHSTQFVQGLALCTLGCMGSSE-------MCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELM---  186 (627)
T ss_dssp             HHHHHHHHHTCSSHHHHHHHHHHHHHHCCHH-------HHHHHHHHHHHHHTCSCHHHHHHHHHHHHHHHHHCSGGG---
T ss_pred             HHHHHHHHhhCCCHHHHHHHHHHHHhcCCHH-------HHHHHHHHHHHHhhCCCHHHHHHHHHHHHHHHHHCHHHH---
Confidence            3444444444555556666666665554211       011334455555555566666666666666654322111   


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                        ..+++.+...+. +.++.++..++.++..+..
T Consensus       187 --~~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~  217 (627)
T 4P6Z_G          187 --EMFLPATKNLLN-EKNHGVLHTSVVLLTEMCE  217 (627)
T ss_dssp             --GGGHHHHTTCTT-CCCHHHHHHHHHHHHHHHH
T ss_pred             --HHHHHHHHHHHh-CCCHHHHHHHHHHHHHHHH
Confidence              234445555554 4455666666666666654


No 435
>1GCJ_B IMPORTIN-BETA; HEAT REPEAT MOTIF, NUCLEAR PORE-TARGETING; HET: MSE; 2.6A {Mus musculus} SCOP: a.118.1.1
Probab=77.16  E-value=0.17  Score=48.43  Aligned_cols=154  Identities=10%  Similarity=0.066  Sum_probs=84.6  Template_Neff=12.800

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLM--------S----SGMSQ----LIGLKEKGLPQIARLLQSG-----  607 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~--------s----~~~~~----~llie~giI~~Ll~LL~s~-----  607 (747)
                      ++.+..++. +.++.++..++.++..++......        .    .....    .. .-..+++.+...+...     
T Consensus       267 ~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~l~~~l~~~l~~~~~~~~  344 (460)
T 1GCJ_B          267 FAITIEAMK-SDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKG-ALQYLVPILTQTLTKQDENDD  344 (460)
T ss_dssp             HHHHHHHHT-CSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSCCSSCCCCHHHH-HHHHHHHHHHHHGGGCCSSSC
T ss_pred             HHHHHHHhh-CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCcchhhhhhHhH-HHHHHHHHHHHHHhcCCCCCC
Confidence            555666666 356777778888888776531000        0    00000    00 0122344444444322     


Q NP_000290.2     608 --NSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL-AKQYFSSSM  684 (747)
Q Consensus       608 --d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~-~~~Lve~gi  684 (747)
                        +..++..+..++..++..... ..+ ..+++.+...+.+      .++.++..++.+|..+....... ....+ ..+
T Consensus       345 ~~~~~~~~~a~~~l~~l~~~~~~-~~~-~~~~~~l~~~l~~------~~~~~r~~a~~~l~~l~~~~~~~~~~~~~-~~~  415 (460)
T 1GCJ_B          345 DDDWNPCKAAGVCLMLLSTCCED-DIV-PHVLPFIKEHIKN------PDWRYRDAAVMAFGSILEGPEPNQLKPLV-IQA  415 (460)
T ss_dssp             TTSCCHHHHHHHHHHHHHHHHGG-GHH-HHHHHHHHHHTTC------SSHHHHHHHHHHHHHTSSSSCHHHHHHHH-HHH
T ss_pred             CCCCcHHHHHHHHHHHHHhhCcc-ccH-HHHHHHHHHHhcC------CChHHHHHHHHHHHHHHcCCChhhHHHHH-HHH
Confidence              345666677777776654110 111 1234444444444      36778889999999988653321 11111 245


Q NP_000290.2     685 LNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       685 L~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.+...+.+. ++.++..++++|..++..
T Consensus       416 ~~~l~~~l~~~-~~~vr~~a~~~l~~l~~~  444 (460)
T 1GCJ_B          416 MPTLIELMKDP-SVVVRDTTAWTVGRICEL  444 (460)
T ss_dssp             HHHHHHHTTCS-CHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHhCCC-CHHHHHHHHHHHHHHHHh
Confidence            66667777666 788999999999988754


No 436
>6GWC_C Tubulin alpha chain, Tubulin beta; microtubule, ARTIFICIAL PROTEIN, ALPHAREP, cytoskeleton; HET: GTP, MES, PGE; 2.6A {Ovis aries}
Probab=76.89  E-value=0.18  Score=43.85  Aligned_cols=121  Identities=12%  Similarity=0.169  Sum_probs=73.3  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+..++. +.++.++..++.+|..+...                ..++.+..++.+.++.++..++.++..+...  
T Consensus       108 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~----------------~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~--  168 (232)
T 6GWC_C          108 AVEPLIKALK-DEDTTVRRIAATALGKIGDE----------------RAVEPLIKALKDEDAAVRLTAARALGEIGDE--  168 (232)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHhccc----------------chHHHHHHHhcCCCHHHHHHHHHHHHHhCCh--
Confidence            3455666665 35667777777777665431                1233455566666777888888777766431  


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                             ..++.+...+.+      .++.++..++.+|..+...           ..+..+..++.+. ++.++..++.+
T Consensus       169 -------~~~~~l~~~l~~------~~~~v~~~a~~~l~~~~~~-----------~~~~~l~~~~~~~-~~~v~~~a~~~  223 (232)
T 6GWC_C          169 -------RAVEPLIKALKD------EDAYVRRAAAQALGKIGGE-----------RVRAAMEKLAETG-TGFARKVAVNY  223 (232)
T ss_pred             -------hHHHHHHHHhcC------CCHHHHHHHHHHHHHhCcC-----------chHHHHHHHHhCC-CHHHHHHHHHH
Confidence                   234445555554      2567777788887776542           2344455555554 66777778777


Q NP_000290.2     708 LSDMW  712 (747)
Q Consensus       708 LsnL~  712 (747)
                      |..+.
T Consensus       224 l~~~~  228 (232)
T 6GWC_C          224 LETHK  228 (232)
T ss_pred             HHHHH
Confidence            77654


No 437
>3QML_D 78 kDa glucose-regulated protein homolog; Armadillo like repeats, CHAPERONE-PROTEIN TRANSPORT; HET: PO4; 2.31A {Saccharomyces cerevisiae}
Probab=76.82  E-value=0.22  Score=49.40  Aligned_cols=104  Identities=8%  Similarity=0.064  Sum_probs=73.8  Template_Neff=7.900

Q NP_000290.2     609 SDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSS--ML  685 (747)
Q Consensus       609 ~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~g--iL  685 (747)
                      ...+..++.-|..++..-++ ..+...+ +..|+.++...    .....++..|+++|+..+.+++.....+.+.+  ++
T Consensus        42 ~~~~~~aLd~L~dl~hdid~a~~~~~~g-~~~L~~~l~~~----~~~~~ir~~Aa~iigsa~qNNP~aq~~~~~~~~~~l  116 (315)
T 3QML_D           42 IARLEDSFDRIMEFAHDYKHGYKIITHE-FALLANLSLNE----NLPLTLRELSTRVITSCLRNNPPVVEFINESFPNFK  116 (315)
T ss_dssp             HHHHHHHHHHHHHHHTSHHHHHHHHHHH-HHHHHHHHHCT----TSCHHHHHHHHHHHHHHHTTCTTHHHHHHHHCTTHH
T ss_pred             HHHHHHHHHHHHHHHccHHHHHHHHHch-HHHHHHHHhCC----CCCHHHHHHHHHHHHHHHhhCHHHHHHHHHHCccHH
Confidence            34455566666666655333 3455566 77777776541    02578999999999999999988888888766  67


Q NP_000290.2     686 NNII---NLCRS---SASPKAAEAARLLLSDMWSSKEL  717 (747)
Q Consensus       686 ~~Ll---~LL~s---~~d~eVr~aAL~aLsnL~~~~~~  717 (747)
                      +.|+   ..+..   ..++.++..++.+|+.++.+.+.
T Consensus       117 ~~Ll~~~~~L~~~~~~~~~~v~~k~L~aLS~Lir~~~~  154 (315)
T 3QML_D          117 SKIMAALSNLNDSNHRSSNILIKRYLSILNELPVTSED  154 (315)
T ss_dssp             HHHHHHHHHHHCC---CTHHHHHHHHHHHHHSCCCGGG
T ss_pred             HHHHHHHHhhccCCCcCCHHHHHHHHHHHHhhcCCCcc
Confidence            7777   44443   22678889999999999988765


No 438
>4G3A_B CLIP-associating protein; TOG domain, HEAT repeat, MAP; HET: GOL; 1.994A {Drosophila melanogaster}
Probab=76.80  E-value=0.18  Score=43.50  Aligned_cols=113  Identities=13%  Similarity=0.037  Sum_probs=64.2  Template_Neff=12.600

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.++.++..++..+..++..............+++.+...+.+.++.++..++.++..++........
T Consensus         6 ~~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~d~~~~v~~~a~~~l~~l~~~~~~~~~   85 (237)
T 4G3A_B            6 PSDLDGFIQQMPKADMRVKVQLAEDLVTFLSDDTNSIVCTDMGFLIDGLMPWLTGSHFKIAQKSLEAFSELIKRLGSDFN   85 (237)
T ss_dssp             CSSHHHHHHHSTTCCHHHHHHHHHHHHHHHHCTTSCCCCSCHHHHHHHHGGGGSSSCHHHHHHHHHHHHHHHHHHGGGGG
T ss_pred             cchHHHHHHhcCcCCHHHHHHHHHHHHHHhhCCCCCcccccHHHHHHHHHHHhcCCcHHHHHHHHHHHHHHHHHhhhhHH
Confidence            34455566666677778888888888887764321111111123556666667667778888888888887754332111


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      .. ...+++.+...+. +.+..++..++.++..+.
T Consensus        86 ~~-~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~  118 (237)
T 4G3A_B           86 AY-TATVLPHVIDRLG-DSRDTVREKAQLLLRDLM  118 (237)
T ss_dssp             GT-HHHHHHHHHHHHT-CSCHHHHHHHHHHHHHHH
T ss_pred             HH-HHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHH
Confidence            11 1234455555554 334445555555555544


No 439
>6IDX_A Engulfment and cell motility protein; Adhesion GPCRs, CELL ADHESION; 1.699A {Homo sapiens}
Probab=76.77  E-value=0.22  Score=52.79  Aligned_cols=157  Identities=13%  Similarity=0.168  Sum_probs=98.0  Template_Neff=8.400

Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG------NSDVVRSGASLLSNMSRHP-LL-HRVMGN  634 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~------d~eVr~~AL~aLsnLa~~~-e~-~~ll~~  634 (747)
                      ..+..++.-|..++.. ..     ....|++.+++..|+.++...      +......++.+|..+.... .. ..+. .
T Consensus       102 ~~~~~~L~~L~~~~~d-~~-----f~~EFi~~~Gl~~L~~~l~~~~~~~~~~~~~l~~~L~al~~lM~~~~~g~~~l~-~  174 (524)
T 6IDX_A          102 ETRLDAMKELAKLSAD-VT-----FATEFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVS-I  174 (524)
T ss_pred             HHHHHHHHHHHHHhcC-hh-----HHHHHHHcChHHHHHHHHHhCCCCCCCChhHHHHHHHHHHHHHhcCcccHhhch-H
Confidence            3444566666666653 22     345557788999999988863      4466777888888888764 32 2222 3


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ..+..|..++...    ..+..+...++.+|..++...+.....+.....+..|+..|... +..++..++.++..|...
T Consensus       175 ~~i~~l~~~l~~~----~~~~~v~~~aL~iL~~l~~~~~~~~~~v~~~~~f~~Lv~~L~~~-d~~~q~~~L~LINaLl~~  249 (524)
T 6IDX_A          175 TFIKQIAGYVSQP----MVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVS-NQEIQTYAIALINALFLK  249 (524)
T ss_pred             HHHHHHHHHhCCC----CCChhHHHHHHHHHHHHHhcCHHHHHHHHcCCCHHHHHHHHccC-CHHHHHHHHHHHHHHHhc
Confidence            4667777777542    00237888899999888775433333222222377788888765 677778887777777654


Q NP_000290.2     715 K------ELQGVLRQQGFDRNML  731 (747)
Q Consensus       715 ~------~~~~~~~~~~~~~~~~  731 (747)
                      .      ++..-|...|+..-..
T Consensus       250 ~~~~~~~~i~~~L~~~gi~~~i~  272 (524)
T 6IDX_A          250 APEDKRQDMANAFAQKHLRSIIL  272 (524)
T ss_pred             CCcccHHHHHHHHHHcCHHHHHH
Confidence            4      3444555666655433


No 440
>6IE1_A Engulfment and cell motility protein; Adhesion GPCR, BAI1-ELMO2 Complex, cell; HET: GOL; 2.48A {Homo sapiens}
Probab=76.77  E-value=0.22  Score=52.79  Aligned_cols=157  Identities=13%  Similarity=0.168  Sum_probs=98.0  Template_Neff=8.400

Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG------NSDVVRSGASLLSNMSRHP-LL-HRVMGN  634 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~------d~eVr~~AL~aLsnLa~~~-e~-~~ll~~  634 (747)
                      ..+..++.-|..++.. ..     ....|++.+++..|+.++...      +......++.+|..+.... .. ..+. .
T Consensus       102 ~~~~~~L~~L~~~~~d-~~-----f~~EFi~~~Gl~~L~~~l~~~~~~~~~~~~~l~~~L~al~~lM~~~~~g~~~l~-~  174 (524)
T 6IE1_A          102 ETRLDAMKELAKLSAD-VT-----FATEFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVS-I  174 (524)
T ss_pred             HHHHHHHHHHHHHhcC-hh-----HHHHHHHcChHHHHHHHHHhCCCCCCCChhHHHHHHHHHHHHHhcCcccHhhch-H
Confidence            3444566666666653 22     345557788999999988863      4466777888888888764 32 2222 3


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ..+..|..++...    ..+..+...++.+|..++...+.....+.....+..|+..|... +..++..++.++..|...
T Consensus       175 ~~i~~l~~~l~~~----~~~~~v~~~aL~iL~~l~~~~~~~~~~v~~~~~f~~Lv~~L~~~-d~~~q~~~L~LINaLl~~  249 (524)
T 6IE1_A          175 TFIKQIAGYVSQP----MVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVS-NQEIQTYAIALINALFLK  249 (524)
T ss_pred             HHHHHHHHHhCCC----CCChhHHHHHHHHHHHHHhcCHHHHHHHHcCCCHHHHHHHHccC-CHHHHHHHHHHHHHHHhc
Confidence            4667777777542    00237888899999888775433333222222377788888765 677778887777777654


Q NP_000290.2     715 K------ELQGVLRQQGFDRNML  731 (747)
Q Consensus       715 ~------~~~~~~~~~~~~~~~~  731 (747)
                      .      ++..-|...|+..-..
T Consensus       250 ~~~~~~~~i~~~L~~~gi~~~i~  272 (524)
T 6IE1_A          250 APEDKRQDMANAFAQKHLRSIIL  272 (524)
T ss_pred             CCcccHHHHHHHHHHcCHHHHHH
Confidence            4      3444555666655433


No 441
>5H2V_A Importin subunit beta-3, Ubiquitin-like-specific protease; nuclear import, PROTEIN TRANSPORT-HYDROLASE complex; 2.8A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=76.57  E-value=0.18  Score=54.22  Aligned_cols=157  Identities=9%  Similarity=0.079  Sum_probs=92.1  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      +++.+...+. +.++.++..++.++..++.....     .... ....+++.|...+.+.++.++..++.+|+.++.. +
T Consensus       849 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  921 (1078)
T 5H2V_A          849 IWPMINTFLL-DNEPILVIFALVVIGDLIQYGGE-----QTAS-MKNAFIPKVTECLISPDARIRQAASYIIGVCAQYAP  921 (1078)
T ss_dssp             GHHHHHHHHH-SSSHHHHHHHHHHHHHHHHHHTT-----TTTT-THHHHHHHHHHHHTCSCHHHHHHHHHHHHHHHHHCT
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhcch-----hhHH-HHHhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHCc
Confidence            3445555555 35667777888888887754221     1111 1245677778888888889999999999999876 2


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. ...+ ..+++.+...+.........+..++..++.+|..+....+....  ....+++.++..+....+..++..++
T Consensus       922 ~~~~~~~-~~~l~~l~~~l~~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~--~~~~~~~~l~~~l~~~~~~~~~~~~~  998 (1078)
T 5H2V_A          922 STYADVC-IPTLDTLVQIVDFPGSKLEENRSSTENASAAIAKILYAYNSNIP--NVDTYTANWFKTLPTITDKEAASFNY  998 (1078)
T ss_dssp             TTTHHHH-TTTHHHHHHHTC--CCSSTTTHHHHHHHHHHHHHHHHHC---------CHHHHHHHTTCCCCSCHHHHHHHH
T ss_pred             cchHHhH-HHHHHHHHHHHhCCCCccccccchHHHHHHHHHHHHHHcccCCC--ChhHHHHHHHHhCCccCCHHHHHHHH
Confidence            21 1111 34666677766521000003567888899999888764322111  11234556666664222567777888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..+...
T Consensus       999 ~~l~~l~~~ 1007 (1078)
T 5H2V_A          999 QFLSQLIEN 1007 (1078)
T ss_dssp             HHHHHHHC-
T ss_pred             HHHHHHHHc
Confidence            888777654


No 442
>1TE4_A conserved protein MTH187; MTH187, Methanobacterium thermoautotrophicum, structural proteomics; NMR {Methanothermobacter thermautotrophicus} SCOP: a.118.1.16
Probab=76.51  E-value=0.19  Score=39.52  Aligned_cols=118  Identities=13%  Similarity=0.147  Sum_probs=65.1  Template_Neff=12.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      ..+.+...+. +.++.++..++..|..+..                 ..++.+...+.+.++.++..++.++..+...  
T Consensus        13 ~~~~~~~~l~-~~~~~~r~~a~~~l~~~~~-----------------~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~~--   72 (131)
T 1TE4_A           13 GLVPRGSHMA-DENKWVRRDVSTALSRMGD-----------------EAFEPLLESLSNEDWRIRGAAAWIIGNFQDE--   72 (131)
T ss_dssp             --------CC-SSCCCSSSSCCSSTTSCSS-----------------TTHHHHHHGGGCSCHHHHHHHHHHHGGGCSH--
T ss_pred             CccccHHHhc-CCCHHHHHHHHHHHHHhcH-----------------HHHHHHHHHhcCCCHHHHHHHHHHHHcCCCh--
Confidence            3455666666 4666777777766654421                 1234455556666777888888888776532  


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                             ..++.|...+.+      .++.++..++.+|..+...           ..++.+...+.+. +..++..++.+
T Consensus        73 -------~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~vr~~a~~~  127 (131)
T 1TE4_A           73 -------RAVEPLIKLLED------DSGFVRSGAARSLEQIGGE-----------RVRAAMEKLAETG-TGFARKVAVNY  127 (131)
T ss_dssp             -------HHHHHHHHHHHH------CCTHHHHHHHHHHHHHCSH-----------HHHHHHHHHTTSC-CTHHHHHHHHH
T ss_pred             -------hhHHHHHHHhcC------CCHHHHHHHHHHHHHhCCH-----------HHHHHHHHHHcCC-CHHHHHHHHHH
Confidence                   133444455544      2567777788888776531           1344455555544 56677766666


Q NP_000290.2     708 LSD  710 (747)
Q Consensus       708 Lsn  710 (747)
                      +..
T Consensus       128 l~~  130 (131)
T 1TE4_A          128 LET  130 (131)
T ss_dssp             GGG
T ss_pred             Hhc
Confidence            543


No 443
>6S47_Bi 60S ribosomal protein L2-A, 60S; New1, ABCF, Ribosomal Protein, Recycling; HET: ATP; 3.28A {Saccharomyces cerevisiae}
Probab=76.45  E-value=0.2  Score=54.82  Aligned_cols=155  Identities=15%  Similarity=0.167  Sum_probs=91.4  Template_Neff=11.700

Q NP_000290.2     548 AIRTYLNLMGKSKK-DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d-~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      +++.|..++.. .+ +.++..++.+|..++.....     .........+++.|+.++.+.++.++..|+.+|..++.. 
T Consensus       127 ~~~~l~~~l~~-~~~~~vr~~a~~~l~~i~~~~~~-----~~~~~~~~~~~~~l~~~l~d~~~~vr~~a~~~L~~l~~~~  200 (972)
T 6S47_Bi         127 VLPTILDYLSS-GAKWQAKMAALSVVDRIREDSAN-----DLLELTFKDAVPVLTDVATDFKPELAKQGYKTLLDYVSIL  200 (972)
T ss_pred             hHHHHHHHcCC-CCCHHHHHHHHHHHHHHHhhCCH-----HHHHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHh
Confidence            46667777763 44 67888889998888543221     111112345777788888888888899999988888753 


Q NP_000290.2     626 PL-L-H----RV---MG--------------------------NQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       626 ~e-~-~----~l---l~--------------------------~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      .. . .    .+   +.                          ..+++.+...+.+.    ..+..++..++++|..++.
T Consensus       201 ~~~~~~~~~~~l~~~l~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~----~~~~~vr~~a~~~l~~l~~  276 (972)
T 6S47_Bi         201 DNLDLSPRYKLIVDTLQDPSKVPESVKSLSSVTFVAEVTEPSLSLLVPILNRSLNLS----SSSQEQLRQTVIVVENLTR  276 (972)
T ss_pred             CcHHHHHHHHHHHHHcCChHHHHHHHHHHHHhhCCCCCCcccHHHHHHHHHHHHhCC----CCCHHHHHHHHHHHHHHHH
Confidence            10 0 0    00   00                          00223333333220    0245677788888888875


Q NP_000290.2     671 --SQPQLAKQYFSSSMLNNIINLC-RSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       671 --~s~e~~~~Lve~giL~~Ll~LL-~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                        ........+ ...+++.|+..+ .+. +..++..|+.+|..++..
T Consensus       277 ~~~~~~~~~~~-~~~i~~~L~~~l~~d~-~~~vr~~a~~~l~~l~~~  321 (972)
T 6S47_Bi         277 LVNNRNEIESF-IPLLLPGIQKVVDTAS-LPEVRELAEKALNVLKED  321 (972)
T ss_pred             hcCChhHcHhh-HHHHHHHHHHHHhcCC-CHHHHHHHHHHHHHHhhh
Confidence              211111111 124566777777 555 778899999999998876


No 444
>1OYZ_A X-RAY STRUCTURE OF YB61_HAEIN NORTHEAST; STRUCTURAL GENOMICS, PSI, Protein Structure; 2.1A {Escherichia coli} SCOP: a.118.1.16
Probab=76.37  E-value=0.19  Score=44.51  Aligned_cols=96  Identities=7%  Similarity=0.086  Sum_probs=47.9  Template_Neff=12.700

Q NP_000290.2     596 GLPQIAR-LLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ  674 (747)
Q Consensus       596 iI~~Ll~-LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e  674 (747)
                      .++.+.. ++.+.++.++..++.+|..+......   .....++.+...+.+      .++.++..++.+|..+..    
T Consensus        91 ~~~~l~~~~l~~~~~~vr~~a~~~l~~~~~~~~~---~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~~~~----  157 (280)
T 1OYZ_A           91 VFNILNNMALNDKSACVRATAIESTAQRCKKNPI---YSPKIVEQSQITAFD------KSTNVRRATAFAISVIND----  157 (280)
T ss_dssp             HHHHHHHHHHHCSCHHHHHHHHHHHHHHHHHCGG---GHHHHHHHHHHHTTC------SCHHHHHHHHHHHHTC------
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCcc---cChhHHHHHHHHhcC------CCHHHHHHHHHHHHhhcc----
Confidence            3444444 44444555555555555554432100   112244455555544      245566666666655442    


Q NP_000290.2     675 LAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMW  712 (747)
Q Consensus       675 ~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~  712 (747)
                             ...++.+..++.+. ++.++..++.++..+.
T Consensus       158 -------~~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~  187 (280)
T 1OYZ_A          158 -------KATIPLLINLLKDP-NGDVRNWAAFAININK  187 (280)
T ss_dssp             --------CCHHHHHHHHTCS-SHHHHHHHHHHHHHHT
T ss_pred             -------hhhHHHHHHHHcCC-CHHHHHHHHHHHHhhc
Confidence                   12345555666655 6677777777777543


No 445
>5NR4_A CLIP-associating protein 2; Microtubules, TOG domain, Tubulin, Structural; 1.198A {Homo sapiens}
Probab=76.18  E-value=0.19  Score=42.69  Aligned_cols=111  Identities=10%  Similarity=0.045  Sum_probs=61.9  Template_Neff=12.900

Q NP_000290.2     595 KGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HR---V--MGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNL  668 (747)
Q Consensus       595 giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~---l--l~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnL  668 (747)
                      ..++.+...+.+.+..++..++..|..+...... ..   .  ....+++.+...+.+      .++.++..++.++..+
T Consensus         6 ~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l   79 (230)
T 5NR4_A            6 RSMEYFCAQVQQKDVGGRLQVGQELLLYLGAPGAISDLEEDLGRLGKTVDALTGWVGS------SNYRVSLMGLEILSAF   79 (230)
T ss_dssp             CCHHHHHHHTTCSCGGGHHHHHHHHHHHHHC-----CTTSCHHHHHHHHHHHHHHHHC------SSHHHHHHHHHHHHHH
T ss_pred             hhHHHHHHHHhCCChhHHHHHHHHHHHHhcCCcccCchHHHHHHHHHHHHHHHHHHcC------CCHHHHHHHHHHHHHH
Confidence            3455566666667778888888888888765211 10   0  012345555666654      3677888888888888


Q NP_000290.2     669 MASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       669 a~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      +...+....... ..+++.++..+.+. +..++..++.++..++.
T Consensus        80 ~~~~~~~~~~~~-~~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~~  122 (230)
T 5NR4_A           80 VDRLSTRFKSYV-AMVIVALIDRMGDA-KDKVRDEAQTLILKLMD  122 (230)
T ss_dssp             HHHHGGGGGGGH-HHHHHHHHHHTTCS-SHHHHHHHHHHHHHHHH
T ss_pred             HHHhhHHHHHHH-HHHHHHHHHHhccC-CHHHHHHHHHHHHHHHH
Confidence            764322111111 23445555555544 45566666666665553


No 446
>5A1V_E ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT; TRANSPORT PROTEIN, COPI, COATOMER, COATED; 21.0A {SACCHAROMYCES CEREVISIAE}
Probab=75.90  E-value=0.22  Score=54.55  Aligned_cols=137  Identities=11%  Similarity=0.073  Sum_probs=78.0  Template_Neff=10.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.|+.++. +.+..++..++.++..+....+.          . ..+++.|...+.+.++.++..++.+|..+.....
T Consensus        69 l~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~----------~-~~i~~~l~~~L~~~~~~vr~~al~~L~~~~~~~~  136 (874)
T 5A1V_E           69 AFFAMTKLFQ-SNDPTLRRMCYLTIKEMSCIAED----------V-IIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTM  136 (874)
T ss_dssp             HHHHHHHGGG-SCCHHHHHHHHHHHHHHHTSCSC----------G-GGHHHHHHHHHHSSSHHHHHHHHHHHHHHCCHHH
T ss_pred             HHHHHHHHHc-CCCHHHHHHHHHHHHHhcccCch----------H-hHHHHHHHHhcCCCChhhHHHHHHHHhhcCCHHH
Confidence            4555666666 36667777777777776653211          1 2345566666666677777777777776643210


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                           ...+++.+...+.+      .++.++..++.++..+....+...     ...++.+...+.+. ++.++..++.+
T Consensus       137 -----~~~l~~~l~~~l~d------~~~~Vr~~a~~~l~~l~~~~~~~~-----~~~~~~l~~~l~~~-~~~vr~~a~~~  199 (874)
T 5A1V_E          137 -----LQAVERYMKQAIVD------KVPSVSSSALVSSLHLLKCSFDVV-----KRWVNEAQEAASSD-NIMVQYHALGL  199 (874)
T ss_dssp             -----HHHHHHHHHHHHTC------SSHHHHHHHHHHHHHHHHHCHHHH-----HHTHHHHHHHHTCC-SHHHHHHHHHH
T ss_pred             -----HHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCHHHH-----HHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence                 01234444455544      256677777777777765322111     13445555555544 56667777766


Q NP_000290.2     708 LSDMWS  713 (747)
Q Consensus       708 LsnL~~  713 (747)
                      |..+..
T Consensus       200 L~~l~~  205 (874)
T 5A1V_E          200 LYHVRK  205 (874)
T ss_dssp             HHHHHC
T ss_pred             HHHHHh
Confidence            666654


No 447
>5NZR_G Coatomer subunit alpha, Coatomer subunit; COPI, coatomer, coated vesicles, Transport; 9.2A {Mus musculus}
Probab=75.90  E-value=0.22  Score=54.55  Aligned_cols=137  Identities=11%  Similarity=0.073  Sum_probs=78.0  Template_Neff=10.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.|+.++. +.+..++..++.++..+....+.          . ..+++.|...+.+.++.++..++.+|..+.....
T Consensus        69 l~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~----------~-~~i~~~l~~~L~~~~~~vr~~al~~L~~~~~~~~  136 (874)
T 5NZR_G           69 AFFAMTKLFQ-SNDPTLRRMCYLTIKEMSCIAED----------V-IIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTM  136 (874)
T ss_pred             HHHHHHHHHc-CCCHHHHHHHHHHHHHhcccCch----------H-hHHHHHHHHhcCCCChhhHHHHHHHHhhcCCHHH
Confidence            4555666666 36667777777777776653211          1 2345566666666677777777777776643210


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                           ...+++.+...+.+      .++.++..++.++..+....+...     ...++.+...+.+. ++.++..++.+
T Consensus       137 -----~~~l~~~l~~~l~d------~~~~Vr~~a~~~l~~l~~~~~~~~-----~~~~~~l~~~l~~~-~~~vr~~a~~~  199 (874)
T 5NZR_G          137 -----LQAVERYMKQAIVD------KVPSVSSSALVSSLHLLKCSFDVV-----KRWVNEAQEAASSD-NIMVQYHALGL  199 (874)
T ss_pred             -----HHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCHHHH-----HHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence                 01234444455544      256677777777777765322111     13445555555544 56667777766


Q NP_000290.2     708 LSDMWS  713 (747)
Q Consensus       708 LsnL~~  713 (747)
                      |..+..
T Consensus       200 L~~l~~  205 (874)
T 5NZR_G          200 LYHVRK  205 (874)
T ss_pred             HHHHHh
Confidence            666654


No 448
>6HWP_A A3_bGFPD; alphaRep, artificial protein, chimera, bidomain; 2.547A {synthetic construct}
Probab=75.54  E-value=0.21  Score=46.83  Aligned_cols=49  Identities=8%  Similarity=0.078  Sum_probs=32.0  Template_Neff=12.900

Q NP_000290.2     654 SEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       654 d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.++..++.++..+..           ...++.+..++.+. ++.++..++.++..+...
T Consensus       129 ~~~vr~~~~~~l~~~~~-----------~~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~~~  177 (409)
T 6HWP_A          129 DWFVRIAAAFALGEIGD-----------ERAVEPLIKALKDE-DGWVRQSAADALGEIGGE  177 (409)
T ss_dssp             SHHHHHHHHHHHHHHTC-----------GGGHHHHHHGGGCS-SHHHHHHHHHHHHHHCCH
T ss_pred             CHHHHHHHHHHHHHhCC-----------hhhHHHHHHHhcCC-CHHHHHHHHHHHHHhcch
Confidence            45666666666666543           12345566666655 678888888888887754


No 449
>3W3U_A Importin subunit beta-3; HEAT repeat, nuclear import, PROTEIN; 2.6A {Saccharomyces cerevisiae}
Probab=75.50  E-value=0.21  Score=53.79  Aligned_cols=152  Identities=16%  Similarity=0.150  Sum_probs=91.0  Template_Neff=13.000

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PL  627 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e  627 (747)
                      ++.+...+. +.++.++..++.+|..++.....     .... .-..+++.+...+.+.++.++..++.++..++.. ..
T Consensus       358 ~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~  430 (1078)
T 3W3U_A          358 FQYLQQMIT-STEWRERFAAMMALSSAAAGCAD-----VLIG-EIPKILDMVIPLINDPHPRVQYGCCKVLGQISTAFSP  430 (1078)
T ss_dssp             HHHHHHHTT-CSSHHHHHHHHHHHHHHTTTTHH-----HHTT-SHHHHHHHHGGGGGCSSHHHHHHHHHHHHHHHHHTTT
T ss_pred             HHHHHHHhc-CCCHHHHHHHHHHHHHHHHccHH-----HHHh-hHHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHHccH
Confidence            344445554 35677888888888888764321     0111 1135666677777777888999999999998865 11


Q NP_000290.2     628 L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      . .......+++.+...+...     .+..++..++.+|..++..... ..... -..++..+...+.+. ++.++..++
T Consensus       431 ~~~~~~~~~~~~~l~~~l~~~-----~~~~vr~~a~~~l~~l~~~~~~~~~~~~-~~~~~~~l~~~l~~~-~~~~~~~~~  503 (1078)
T 3W3U_A          431 FIQRTAHDRILPALISKLTSE-----CTSRVQTHAAAALVAFSEFASKDILEPY-LDSLLTNLLVLLQSN-KLYVQEQAL  503 (1078)
T ss_dssp             HHHHHHHHHHHHHHHHHSSTT-----SCHHHHHHHHHHHHHHHTTCCHHHHGGG-HHHHHHHHHHHHTCS-SHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHcCCC-----CCHHHHHHHHHHHHHHHHhCChhhhHHH-HHHHHHHHHHHhcCC-CHHHHHHHH
Confidence            1 1111123555566655521     2567788888888888764221 11111 123556666666655 667777788


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..++..
T Consensus       504 ~~l~~l~~~  512 (1078)
T 3W3U_A          504 TTIAFIAEA  512 (1078)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHH
Confidence            887776643


No 450
>4QMI_B Cytoskeleton-associated protein 5; PROTEIN BINDING, TOG domain; 1.9A {Homo sapiens}
Probab=75.47  E-value=0.21  Score=43.16  Aligned_cols=107  Identities=13%  Similarity=0.065  Sum_probs=67.9  Template_Neff=12.600

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+........... ...+++.+...+.+.+..++..++.++..+.....     
T Consensus        59 ~~~~~l~~~l~d~~~~vr~~a~~~l~~l~~~~~~~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~-----  132 (240)
T 4QMI_B           59 ELPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQH-VKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTG-----  132 (240)
T ss_dssp             THHHHHHHHTTCSSHHHHHHHHHHHHHHHHHHGGGGGGG-CCCCCHHHHHHTTCSSHHHHHHHHHHHHHHHHHHC-----
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHhcHHHHHH-HHHHHHHHHHHhhcCCHHHHHHHHHHHHHHHHHhC-----
Confidence            344555556666777888888888888876533221111 12355666666666667788888888877765422     


Q NP_000290.2     325 TRRQNGI--REAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL--~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                        ...++  +.+...+. +.++.++..++.++..++..
T Consensus       133 --~~~~~~~~~l~~~l~-~~~~~~r~~~~~~l~~l~~~  167 (240)
T 4QMI_B          133 --MKEWLEGEDLSEELK-KENPFLRQELLGWLAEKLPT  167 (240)
T ss_dssp             --SHHHHSSSHHHHHHT-SCCHHHHHHHHHHHHHHGGG
T ss_pred             --hhHhccHHHHHHHHh-cCCHHHHHHHHHHHHHHHHh
Confidence              11244  55566665 55677888888888877653


No 451
>4QMJ_A Cytoskeleton-associated protein 5; PROTEIN BINDING, TOG DOMAIN; 2.498A {Homo sapiens}
Probab=75.47  E-value=0.21  Score=43.16  Aligned_cols=107  Identities=13%  Similarity=0.065  Sum_probs=67.9  Template_Neff=12.600

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+........... ...+++.+...+.+.+..++..++.++..+.....     
T Consensus        59 ~~~~~l~~~l~d~~~~vr~~a~~~l~~l~~~~~~~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~-----  132 (240)
T 4QMJ_A           59 ELPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQH-VKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTG-----  132 (240)
T ss_dssp             THHHHHHHHTTCSSHHHHHHHHHHHHHHHHHHGGGGGGG-CCCCCHHHHHGGGCSSHHHHHHHHHHHHHHHHHHC-----
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHhcHHHHHH-HHHHHHHHHHHhhcCCHHHHHHHHHHHHHHHHHhC-----
Confidence            344555556666777888888888888876533221111 12355666666666667788888888877765422     


Q NP_000290.2     325 TRRQNGI--REAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL--~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                        ...++  +.+...+. +.++.++..++.++..++..
T Consensus       133 --~~~~~~~~~l~~~l~-~~~~~~r~~~~~~l~~l~~~  167 (240)
T 4QMJ_A          133 --MKEWLEGEDLSEELK-KENPFLRQELLGWLAEKLPT  167 (240)
T ss_dssp             --SHHHHSSSHHHHHHH-SSCHHHHHHHHHHHHHHGGG
T ss_pred             --hhHhccHHHHHHHHh-cCCHHHHHHHHHHHHHHHHh
Confidence              11244  55566665 55677888888888877653


No 452
>2IX8_A ELONGATION FACTOR 3A; NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, PHOSPHORYLATION, ELONGATION; 6.0A {SACCHAROMYCES CEREVISIAE}
Probab=75.43  E-value=0.22  Score=54.34  Aligned_cols=153  Identities=11%  Similarity=0.112  Sum_probs=91.2  Template_Neff=11.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      .++.|+..+..+.++.++..++.+|..++.....     .... .-..+++.|..++.+.+..++..|+.+|..++... 
T Consensus       128 ~l~~l~~~l~~~~~~~vr~~al~~L~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~d~~~~vr~~a~~~l~~l~~~~~  201 (976)
T 2IX8_A          128 LLPHLTNAIVETNKWQEKIAILAAFSAMVDAAKD-----QVAL-RMPELIPVLSETMWDTKKEVKAAATAAMTKATETVD  201 (976)
T ss_dssp             HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHSHH-----HHHH-HHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHSTTCC
T ss_pred             HHHHHHHHHhhcCCHHHHHHHHHHHHHHHHHHHH-----hHHh-hchhHHHHHHHhhcCCCHHHHHHHHHHHHHHHHhcC
Confidence            4556666662135667778888888888754221     1111 12356777778887778888888888888877531 


Q NP_000290.2     627 -LL-H----RVMG-----------------------------NQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       627 -e~-~----~ll~-----------------------------~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                       .. .    .++.                             ..+++.+...+.+      .++.++..++.+|..++..
T Consensus       202 ~~~~~~~~~~l~~~l~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~l~~l~~~l~~------~~~~vr~~a~~~L~~l~~~  275 (976)
T 2IX8_A          202 NKDIERFIPSLIQCIADPTEVPETVHLLGATTFVAEVTPATLSIMVPLLSRGLNE------RETGIKRKSAVIIDNMCKL  275 (976)
T ss_dssp             SSTTCCCHHHHHHHHHCGGGHHHHHHHCSCTTCCSCCCHHHHHHHHHHHHHHHTS------SSHHHHHHHHHHHHHHHTT
T ss_pred             cHHHHHHHHHHHHHhcCCCCchHHHHHHHHhhhhccCCchhHHHHHHHHHccCCC------CChhHHHHHHHHHHHHHHH
Confidence             00 0    0000                             0233344444443      3567888888888888764


Q NP_000290.2     672 QPQLAK-QYFSSSMLNNIINLCRSSAS-PKAAEAARLLLSDMWS  713 (747)
Q Consensus       672 s~e~~~-~Lve~giL~~Ll~LL~s~~d-~eVr~aAL~aLsnL~~  713 (747)
                      .+.... .-....+++.|...+.+. + +.++..++.+|..++.
T Consensus       276 ~~~~~~~~~~~~~~~~~l~~~l~d~-~~~~vr~~a~~~l~~l~~  318 (976)
T 2IX8_A          276 VEDPQVIAPFLGKLLPGLKSNFATI-ADPEAREVTLRALKTLRR  318 (976)
T ss_dssp             CCCHHHHHHHHTTTHHHHHHHHHHC-CCHHHHHHHHHHHHHHHH
T ss_pred             cCCHHHHHHHHHHHHHHHHHhcCCC-CCHHHHHHHHHHHHHHHH
Confidence            211110 001123566677777665 5 7888899999988865


No 453
>5XAH_A Importin-4; Histone, Chromatin, Assembly, PROTEIN TRANSPORT; HET: MSE; 3.004A {Homo sapiens}
Probab=75.38  E-value=0.21  Score=46.90  Aligned_cols=162  Identities=12%  Similarity=0.072  Sum_probs=86.9  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSG--------MSQLIGLKEKGLPQIARLLQS-GNSDVVRSGASL  618 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~--------~~~~llie~giI~~Ll~LL~s-~d~eVr~~AL~a  618 (747)
                      +++.++..+. +.++.++..++.+|..++..... ...        ..... .-..+++.+...+.+ .++.++..++.+
T Consensus        33 i~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-~~~~~~~~~~~~~~~~-~~~~~~~~l~~~l~~~~~~~~~~~~~~~  109 (416)
T 5XAH_A           33 VFEEVFKLLE-CPHLNVRKAAHEALGQFCCALHK-ACQSCPSEPNTAALQA-ALARVVPSYMQAVNRERERQVVMAVLEA  109 (416)
T ss_dssp             HHHHHHGGGS-CSCHHHHHHHHHHHHHHHHHHHH-HHTTSCCHHHHHHHHH-HHHHHHHHHHHHHTTCCCHHHHHHHHHH
T ss_pred             HHHHHHHHcC-CCCHHHHHHHHHHHHHHHHHHHH-HhccCCCCCCcHHHHH-HHHHHHHHHHHHHhhccHHHHHHHHHHH
Confidence            4566667776 46778888999999888764211 000        00000 112455666666655 567788889999


Q NP_000290.2     619 LSNMSRHPLLH-R---VMGNQVFPEVTRLLTSHTG--------------NTSNSEDILSSACYTVRNLMASQ-PQLAKQY  679 (747)
Q Consensus       619 LsnLa~~~e~~-~---ll~~giI~~Ll~LL~s~s~--------------~~~~d~eVr~~Al~aLsnLa~~s-~e~~~~L  679 (747)
                      |..++...... .   .....+++.+...+.....              ....++.++..++.++..++... +.....+
T Consensus       110 l~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~  189 (416)
T 5XAH_A          110 LTGVLRSCGTLTLKPPGRLAELCGVLKAVLQRKTACQDTDEEEEEEDDDQAEYDAMLLEHAGEAIPALAAAAGGDSFAPF  189 (416)
T ss_dssp             HHHHHHHTTHHHHCSTTHHHHHHHHHHHHHTTCSTTC-------------CHHHHHHHHHHHHHHHHHHHHHTSTTTHHH
T ss_pred             HHHHHHHhcccccCCccHHHHHHHHHHHHHhccchhcCCCcccccccccHHHHHHHHHHHHHHHHHHHHHHhCccchHHH
Confidence            98887652111 0   1112345555555543100              00004567778888888887642 1111111


Q NP_000290.2     680 FSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       680 ve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      + ..+++.+...+....+..++..++.++..++.
T Consensus       190 ~-~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~  222 (416)
T 5XAH_A          190 F-AGFLPLLVCKTKQGCTVAEKSFAVGTLAETIQ  222 (416)
T ss_dssp             H-HHHHHHHHHTTSSSSCHHHHHHHHHHHHHHHH
T ss_pred             H-HHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHH
Confidence            1 13455555555433135666777777776664


No 454
>5XAH_C Importin-4; Histone, Chromatin, Assembly, PROTEIN TRANSPORT; HET: MSE; 3.004A {Homo sapiens}
Probab=75.38  E-value=0.21  Score=46.90  Aligned_cols=162  Identities=12%  Similarity=0.072  Sum_probs=86.9  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSG--------MSQLIGLKEKGLPQIARLLQS-GNSDVVRSGASL  618 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~--------~~~~llie~giI~~Ll~LL~s-~d~eVr~~AL~a  618 (747)
                      +++.++..+. +.++.++..++.+|..++..... ...        ..... .-..+++.+...+.+ .++.++..++.+
T Consensus        33 i~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-~~~~~~~~~~~~~~~~-~~~~~~~~l~~~l~~~~~~~~~~~~~~~  109 (416)
T 5XAH_C           33 VFEEVFKLLE-CPHLNVRKAAHEALGQFCCALHK-ACQSCPSEPNTAALQA-ALARVVPSYMQAVNRERERQVVMAVLEA  109 (416)
T ss_dssp             HHHHHHHGGG-SSCHHHHHHHHHHHHHHHHHHHH-HHHHSCCHHHHHHHHH-HHHHHHHHHHHHHHHCCCHHHHHHHHHH
T ss_pred             HHHHHHHHcC-CCCHHHHHHHHHHHHHHHHHHHH-HhccCCCCCCcHHHHH-HHHHHHHHHHHHHhhccHHHHHHHHHHH
Confidence            4566667776 46778888999999888764211 000        00000 112455666666655 567788889999


Q NP_000290.2     619 LSNMSRHPLLH-R---VMGNQVFPEVTRLLTSHTG--------------NTSNSEDILSSACYTVRNLMASQ-PQLAKQY  679 (747)
Q Consensus       619 LsnLa~~~e~~-~---ll~~giI~~Ll~LL~s~s~--------------~~~~d~eVr~~Al~aLsnLa~~s-~e~~~~L  679 (747)
                      |..++...... .   .....+++.+...+.....              ....++.++..++.++..++... +.....+
T Consensus       110 l~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~  189 (416)
T 5XAH_C          110 LTGVLRSCGTLTLKPPGRLAELCGVLKAVLQRKTACQDTDEEEEEEDDDQAEYDAMLLEHAGEAIPALAAAAGGDSFAPF  189 (416)
T ss_dssp             HHHHHHHHGGGGSCSTTHHHHHHHHHHHHHHTCSTTTC-----------CTTHHHHHHHHHHTHHHHHHHHHTSTTTHHH
T ss_pred             HHHHHHHhcccccCCccHHHHHHHHHHHHHhccchhcCCCcccccccccHHHHHHHHHHHHHHHHHHHHHHhCccchHHH
Confidence            98887652111 0   1112345555555543100              00004567778888888887642 1111111


Q NP_000290.2     680 FSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       680 ve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      + ..+++.+...+....+..++..++.++..++.
T Consensus       190 ~-~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~  222 (416)
T 5XAH_C          190 F-AGFLPLLVCKTKQGCTVAEKSFAVGTLAETIQ  222 (416)
T ss_dssp             H-HHHHHHHHHTTSTTSCHHHHHHHHHHHHHHHH
T ss_pred             H-HHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHH
Confidence            1 13455555555433135666777777776664


No 455
>5H2V_A Importin subunit beta-3, Ubiquitin-like-specific protease; nuclear import, PROTEIN TRANSPORT-HYDROLASE complex; 2.8A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=75.07  E-value=0.22  Score=53.62  Aligned_cols=154  Identities=16%  Similarity=0.115  Sum_probs=91.6  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      .++.+...+. +.++.++..++.+|..++.....     .... .-..+++.+...+.+.++.++..++.++..++... 
T Consensus       357 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  429 (1078)
T 5H2V_A          357 LFQYLQQMIT-STEWRERFAAMMALSSAAEGCAD-----VLIG-EIPKILDMVIPLINDPHPRVQYGCCNVLGQISTDFS  429 (1078)
T ss_dssp             HHHHHHHHTT-CSCHHHHHHHHHHHHHHTTTTHH-----HHTT-SHHHHHHHHGGGGGCSSHHHHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhccHH-----HHHh-hHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHhhcc
Confidence            4555555565 35677888888888888764321     1111 11356666777777777889999999999988652 


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. .......+++.+...+.+.     .++.++..++.+|..++...........-..++..+...+.+. ++.++..++
T Consensus       430 ~~~~~~~~~~~~~~l~~~l~~~-----~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~  503 (1078)
T 5H2V_A          430 PFIQRTAHDRILPALISKLTSE-----CTSRVQTHAAAALVNFSEFASKDILEPYLDSLLTNLLVLLQSN-KLYVQEQAL  503 (1078)
T ss_dssp             THHHHHHHHHHHHHHHHTTSTT-----SCHHHHHHHHHHHHHHHTTCCHHHHGGGHHHHHHHHHHHTTCS-SHHHHHHHH
T ss_pred             HHHHHHHHHhHHHHHHHHcccC-----CCHHHHHHHHHHHHHHHhcCChhhHHHHHHHHHHHHHHHHhCC-CHHHHHHHH
Confidence            11 1111123555555555431     2567788888888888764321110011123455666666554 567777777


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .++..++..
T Consensus       504 ~~l~~l~~~  512 (1078)
T 5H2V_A          504 TTIAFIAEA  512 (1078)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHH
Confidence            777776653


No 456
>6OWT_A AP-2 complex subunit alpha, AP-2; AP, HIV, Nef, trafficking, Protein;{Rattus norvegicus}
Probab=74.95  E-value=0.24  Score=54.59  Aligned_cols=140  Identities=16%  Similarity=0.153  Sum_probs=90.7  Template_Neff=11.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.++.++. +.+...+..+..++..+......          ....++..|...+.+.++.++..|+.+|+++.....
T Consensus        75 ~~~~l~~ll~-s~~~~~r~~~~~~l~~l~~~~~~----------~~~~ii~~l~~~l~~~~~~vr~~Al~~l~~~~~~~~  143 (939)
T 6OWT_A           75 GHMEAVNLLS-SNRYTEKQIGYLFISVLVNSNSE----------LIRLINNAIKNDLASRNPTFMGLALHCIANVGSREM  143 (939)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHccCChH----------HHHHHHHHHHHHhcCCCHHHHHHHHHHHHHhcCHHH
Confidence            3455666776 46667777777777777653221          112456667777777888899999999888764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                           ...+++.+..++  .+      .++.++..++.+|..+....+...   .....++.|..++.+. +..++..++
T Consensus       144 -----~~~l~~~l~~~l~~~~------~~~~vR~~a~~~L~~l~~~~~~~~---~~~~~~~~l~~lL~d~-~~~vr~~a~  208 (939)
T 6OWT_A          144 -----AEAFAGEIPKILVAGD------TMDSVKQSAALCLLRLYRTSPDLV---PMGDWTSRVVHLLNDQ-HLGVVTAAT  208 (939)
T ss_pred             -----HHHHHHHHHHHHcCCC------CCHHHHHHHHHHHHHHHHHCchhc---ChhhHHHHHHHHhcCC-CHHHHHHHH
Confidence                 112444555555  33      367889999999999876433221   1234567777777765 677888888


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .+|..+..
T Consensus       209 ~~L~~l~~  216 (939)
T 6OWT_A          209 SLITTLAQ  216 (939)
T ss_pred             HHHHHHHH
Confidence            88877765


No 457
>4G3A_B CLIP-associating protein; TOG domain, HEAT repeat, MAP; HET: GOL; 1.994A {Drosophila melanogaster}
Probab=74.93  E-value=0.22  Score=42.89  Aligned_cols=107  Identities=15%  Similarity=0.166  Sum_probs=71.3  Template_Neff=12.600

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIA-RLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll-~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .++.++..+. +.+..++..++.+|..+......          ....+++.+. .++.+.++.++..++.++..++...
T Consensus        91 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~----------~~~~~~~~l~~~~l~~~~~~~r~~a~~~l~~l~~~~  159 (237)
T 4G3A_B           91 VLPHVIDRLG-DSRDTVREKAQLLLRDLMEHRVL----------PPQALIDKLATSCFKHKNAKVREEFLQTIVNALHEY  159 (237)
T ss_dssp             HHHHHHHHHT-CSCHHHHHHHHHHHHHHHHTTSS----------CHHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHcCCC----------CHHHHHHHHHHHHhhCCCHHHHHHHHHHHHHHHHHh
Confidence            5666777776 35667788888888888753111          0123556666 6777777888999999998887652


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                      .........+++.+...+.+      .++.++..++.++..+...
T Consensus       160 ~~~~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~  198 (237)
T 4G3A_B          160 GTQQLSVRVYIPPVCALLGD------PTVNVREAAIQTLVEIYKH  198 (237)
T ss_dssp             HHHHCCCGGGHHHHHHHTTC------SSHHHHHHHHHHHHHHHHH
T ss_pred             CCccccHHHHHHHHHHHHCC------CCHHHHHHHHHHHHHHHHH
Confidence            11111113456667777765      3678899999999988764


No 458
>4XL5_C Green fluorescent protein, bGFP-A; AlphaRep Scaffold, Complex, EGFP, PROTEIN; HET: CRO; 2.0A {Aequorea victoria}
Probab=74.58  E-value=0.23  Score=43.80  Aligned_cols=121  Identities=12%  Similarity=0.165  Sum_probs=73.5  Template_Neff=12.400

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..+...                ..++.+...+.+.++.++..++.+|..+...  
T Consensus       139 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~----------------~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~~--  199 (263)
T 4XL5_C          139 AVEPLIKALK-DEDPWVRLTAARALGQIGDE----------------RAVEPLIKALKDEDASVRKAAAVALGQIGDE--  199 (263)
T ss_dssp             GHHHHHHHTT-CSSHHHHHHHHHHHHHHCCG----------------GGHHHHHHHTTCSSHHHHHHHHHHHHHHCCG--
T ss_pred             hHHHHHHHhh-CCCHHHHHHHHHHHHhhCCH----------------HHHHHHHHHhcCCCHHHHHHHHHHHHHhCCh--
Confidence            4455666666 35667777777777655431                2234455566666677788888877766431  


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                             ..++.+..++.+      .+..++..++.+|..+...           ...+.+..++.+. ++.++..++.+
T Consensus       200 -------~~~~~l~~~l~~------~~~~~~~~a~~~l~~~~~~-----------~~~~~l~~~~~~~-~~~vr~~a~~~  254 (263)
T 4XL5_C          200 -------RAVEPLIKALKD------EDEYVRQRAASALGKIGGE-----------RVRAAMEKLAEPA-PGFARKVAVNY  254 (263)
T ss_dssp             -------GGHHHHHHHTTC------SSHHHHHHHHHHHHHHCHH-----------HHHHHHHHHTTTC-CHHHHHHHHHH
T ss_pred             -------hhHHHHHHHhcC------CCHHHHHHHHHHHHhhCcH-----------HHHHHHHHHhcCC-CcHHHHHHHHH
Confidence                   234455555554      2566777888888776542           2334444555544 66788888888


Q NP_000290.2     708 LSDMW  712 (747)
Q Consensus       708 LsnL~  712 (747)
                      |..+.
T Consensus       255 l~~~~  259 (263)
T 4XL5_C          255 LETHK  259 (263)
T ss_dssp             HHHCC
T ss_pred             HHHHH
Confidence            77654


No 459
>4FDD_A Transportin-1, RNA-binding protein FUS; HEAT repeats, Karyopherin, nuclear import; 2.3A {Homo sapiens}
Probab=74.48  E-value=0.23  Score=51.35  Aligned_cols=155  Identities=9%  Similarity=0.106  Sum_probs=92.6  Template_Neff=13.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIG--LKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~ll--ie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+...+. +.++.++..++.+|..+......   ......+  .-..+++.+...+.+.++.++..++.+|..++..
T Consensus       129 ~~~~l~~~l~-~~~~~~~~~al~~l~~l~~~~~~---~~~~~~~~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  204 (852)
T 4FDD_A          129 LLPKLCSLLD-SEDYNTCEGAFGALQKICEDSAE---ILDSDVLDRPLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIIS  204 (852)
T ss_dssp             HHHHHHHHHS-CSSHHHHHHHHHHHHHHHHHHTT---HHHHCSSSSCHHHHHHHHTTTTTCSSHHHHHHHHHHHHTTTTT
T ss_pred             HHHHHHHHHc-CCCHHHHHHHHHHHHHHHHHHHh---hcchhhccHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHH
Confidence            3455555565 35667777888888877753210   0000000  1134566677777777788899999999888765


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      ... .......+++.+...+.+      .++.++..++.++..+....+....... ..+++.+...+.+. ++.++..+
T Consensus       205 ~~~~~~~~~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~-~~~v~~~a  276 (852)
T 4FDD_A          205 RTQALMLHIDSFIENLFALAGD------EEPEVRKNVCRALVMLLEVRMDRLLPHM-HNIVEYMLQRTQDQ-DENVALEA  276 (852)
T ss_dssp             TCHHHHTSHHHHHHHHHHHHTC------CCHHHHHHHHHHHHHHHHHCHHHHGGGH-HHHHHHHHHHHTCS-SHHHHHHH
T ss_pred             hHHHHHHhHHHHHHHHHHHcCC------CCHHHHHHHHHHHHHHHHHcHHHHHHhH-HHHHHHHHHhcCCC-CHHHHHHH
Confidence            211 111112355556666654      3567888899999888765332211111 23456666666655 67788888


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.+|..++..
T Consensus       277 ~~~l~~l~~~  286 (852)
T 4FDD_A          277 CEFWLTLAEQ  286 (852)
T ss_dssp             HHHHHHHTTS
T ss_pred             HHHHHHHhcC
Confidence            8888887754


No 460
>4D4Z_A DEOXYHYPUSINE HYDROXYLASE (E.C.1.14.99.29); OXIDOREDUCTASE, EIF-5A, HYPUSINE; HET: B3P, GOL; 1.7A {HOMO SAPIENS}
Probab=74.40  E-value=0.23  Score=44.22  Aligned_cols=124  Identities=11%  Similarity=0.101  Sum_probs=69.5  Template_Neff=12.700

Q NP_000290.2     546 SDAIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      ...++.|...+. +.+  +.++..++.+|..+..                ...++.+...+.+.++.++..++.+|..+.
T Consensus         9 ~~~~~~l~~~l~-~~~~~~~~r~~a~~~l~~~~~----------------~~~~~~l~~~l~~~~~~~r~~a~~~l~~~~   71 (294)
T 4D4Z_A            9 EQEVDAIGQTLV-DPKQPLQARFRALFTLRGLGG----------------PGAIAWISQAFDDDSALLKHELAYCLGQMQ   71 (294)
T ss_dssp             HHHHHHHHHHHH-CTTSCHHHHHHHHHHHHHHCS----------------HHHHHHHHHGGGCSCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHHc-CCCCCHHHHHHHHHHHHhhcC----------------hhHHHHHHHHhCCCCHHHHHHHHHHHHhcC
Confidence            345666777776 344  4577777777766532                123445556666667777888877777664


Q NP_000290.2     624 RHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       624 ~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                      ..         ..++.+..++.+.    ..++.++..++.+|..+...           ..++.+...+.+. ++.++..
T Consensus        72 ~~---------~~~~~l~~~l~~~----~~~~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~v~~~  126 (294)
T 4D4Z_A           72 DA---------RAIPMLVDVLQDT----RQEPMVRHEAGEALGAIGDP-----------EVLEILKQYSSDP-VIEVAET  126 (294)
T ss_dssp             CG---------GGHHHHHHHHHCT----TSCHHHHHHHHHHHHHHCCG-----------GGHHHHHHHTTCS-SHHHHHH
T ss_pred             Cc---------chHHHHHHHhhCC----CCCHHHHHHHHHHHHHhCCH-----------HHHHHHHHHccCC-CchHHHH
Confidence            31         2334455555441    01456777777777766431           1233444445444 5556666


Q NP_000290.2     704 ARLLLSDM  711 (747)
Q Consensus       704 AL~aLsnL  711 (747)
                      ++.++..+
T Consensus       127 a~~~l~~~  134 (294)
T 4D4Z_A          127 CQLAVRRL  134 (294)
T ss_dssp             HHHHHHHH
T ss_pred             HHHHHHHH
Confidence            65555544


No 461
>4D50_A DEOXYHYPUSINE HYDROXYLASE (E.C.1.14.99.29); OXIDOREDUCTASE; HET: GAI; 1.7A {HOMO SAPIENS}
Probab=74.40  E-value=0.23  Score=44.22  Aligned_cols=124  Identities=11%  Similarity=0.101  Sum_probs=69.5  Template_Neff=12.700

Q NP_000290.2     546 SDAIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      ...++.|...+. +.+  +.++..++.+|..+..                ...++.+...+.+.++.++..++.+|..+.
T Consensus         9 ~~~~~~l~~~l~-~~~~~~~~r~~a~~~l~~~~~----------------~~~~~~l~~~l~~~~~~~r~~a~~~l~~~~   71 (294)
T 4D50_A            9 EQEVDAIGQTLV-DPKQPLQARFRALFTLRGLGG----------------PGAIAWISQAFDDDSALLKHELAYCLGQMQ   71 (294)
T ss_dssp             HHHHHHHHHHHH-CTTSCHHHHHHHHHHHHHHCS----------------HHHHHHHHHGGGSSCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHHc-CCCCCHHHHHHHHHHHHhhcC----------------hhHHHHHHHHhCCCCHHHHHHHHHHHHhcC
Confidence            345666777776 344  4577777777766532                123445556666667777888877777664


Q NP_000290.2     624 RHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       624 ~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                      ..         ..++.+..++.+.    ..++.++..++.+|..+...           ..++.+...+.+. ++.++..
T Consensus        72 ~~---------~~~~~l~~~l~~~----~~~~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~v~~~  126 (294)
T 4D50_A           72 DA---------RAIPMLVDVLQDT----RQEPMVRHEAGEALGAIGDP-----------EVLEILKQYSSDP-VIEVAET  126 (294)
T ss_dssp             CG---------GGHHHHHHHHHCT----TSCHHHHHHHHHHHHHHCCG-----------GGHHHHHHHTTCS-SHHHHHH
T ss_pred             Cc---------chHHHHHHHhhCC----CCCHHHHHHHHHHHHHhCCH-----------HHHHHHHHHccCC-CchHHHH
Confidence            31         2334455555441    01456777777777766431           1233444445444 5556666


Q NP_000290.2     704 ARLLLSDM  711 (747)
Q Consensus       704 AL~aLsnL  711 (747)
                      ++.++..+
T Consensus       127 a~~~l~~~  134 (294)
T 4D50_A          127 CQLAVRRL  134 (294)
T ss_dssp             HHHHHHHH
T ss_pred             HHHHHHHH
Confidence            65555544


No 462
>6QH5_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=74.19  E-value=0.24  Score=50.25  Aligned_cols=69  Identities=16%  Similarity=0.194  Sum_probs=49.1  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLM--GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL--~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+...+  . +.++.++..++.+|..+....+.        .......++.+..++.+.++.++..++.+|..+...
T Consensus       147 l~~~l~~~l~~~-~~~~~vr~~a~~~L~~l~~~~~~--------~~~~~~~~~~l~~~l~~~~~~vr~~a~~~L~~l~~~  217 (621)
T 6QH5_A          147 FAGEIPKILVAG-DTMDSVKQSAALCLLRLYRTSPD--------LVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQK  217 (621)
T ss_pred             HHHHHHHHhcCC-CCCHHHHHHHHHHHHHHHHhChH--------HccHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHh
Confidence            355566666  5 46778888999999988764221        111245677788888888888999999999888764


No 463
>5LPH_B Centrosomal protein of 104 kDa; TOG domain, HEAT repeat, Tubulin; HET: MSE; 2.25A {Homo sapiens}
Probab=74.03  E-value=0.26  Score=45.88  Aligned_cols=155  Identities=10%  Similarity=0.057  Sum_probs=88.9  Template_Neff=10.900

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLM---SSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~---s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ++.+...+. +.+..++..++.++..++......   ... .... .-..+++.|+..+.+.++.++..+..+|..++..
T Consensus        94 ~~~l~~~l~-d~~~~v~~~a~~~l~~l~~~~~~~~~~~~~-~~~~-~l~~ll~~ll~~l~d~~~~vr~~a~~~l~~l~~~  170 (288)
T 5LPH_B           94 VFLVRRAIK-DIVTSVFQASLKLLKMIITQYIPKHKLSKL-ETAH-CVERTIPVLLTRTGDSSARLRVTAANFIQEMALF  170 (288)
T ss_pred             HHHHHHHhC-CCCHHHHHHHHHHHHHHHHHHcccCCCCHH-HHHH-HHHHHHHHHHHHhCCCcHHHHHHHHHHHHHHHcC
Confidence            444555565 466778888888888776532000   000 0011 1234667777777777788888899888888765


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .....  ...++..+...+...     .++.++..++.+|..++...........-..+++.+...+.+. +..+|..+.
T Consensus       171 ~~~~~--~~~v~~~l~~~l~~~-----~~~~~~~~~l~~l~~l~~~~~~~~~~~~~~~i~~~l~~~l~~~-~~~VR~~a~  242 (288)
T 5LPH_B          171 KEVKS--LQIIPSYLVQPLKAN-----SSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHR-VYEVRETAV  242 (288)
T ss_pred             CCCCc--hhhHHHHHhhccccC-----CCHHHHHHHHHHHHHHHHHHCCCCCCccHHHHHHHHHHHhCCC-CHHHHHHHH
Confidence            21100  011223332333321     2466777788888877654322111111224567777777766 789999999


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .++..+...
T Consensus       243 ~~l~~l~~~  251 (288)
T 5LPH_B          243 RIILDMYRQ  251 (288)
T ss_pred             HHHHHHHHH
Confidence            998887653


No 464
>1QBK_B STRUCTURE OF THE KARYOPHERIN BETA2-RAN; HEAT REPEATS, NUCLEAR TRANSPORT PROTEIN; HET: GNP; 3.0A {Homo sapiens} SCOP: a.118.1.1
Probab=73.90  E-value=0.24  Score=51.58  Aligned_cols=156  Identities=9%  Similarity=0.104  Sum_probs=93.2  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLI--GLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~l--lie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+...+. +.++.++..++.+|..++.....   ......  -.-..+++.+...+.+.++.++..++.+|..+...
T Consensus       129 ~~~~l~~~l~-~~~~~~~~~al~~l~~l~~~~~~---~~~~~~~~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  204 (890)
T 1QBK_B          129 LLPKLCSLLD-SEDYNTCEGAFGALQKICEDSAE---ILDSDVLDRPLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIIS  204 (890)
T ss_pred             HHHHHHHHhc-CCChhHHHHHHHHHHHHHHHHHH---hcchhhccHhHHhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHH
Confidence            4555666665 35667777888888887754221   000000  01134566677777777788899999999988765


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      ... .......+++.+...+.+      .+..++..++.+|..++...+....... ..+++.+...+.+. ++.++..+
T Consensus       205 ~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~-~~~v~~~a  276 (890)
T 1QBK_B          205 RTQALMLHIDSFTENLFALAGD------EEPEVRKNVCRALVMLLEVRMDRLLPHM-HNIVEYMLQRTQDQ-DENVALEA  276 (890)
T ss_pred             hcHHHHHcHHHHHHHHHHHcCC------CCHHHHHHHHHHHHHHHHhCHHHHHHhH-HHHHHHHHHHhcCC-CHHHHHHH
Confidence            211 111112345555555554      2567788888888888765332221111 23456666666655 67788888


Q NP_000290.2     705 RLLLSDMWSSK  715 (747)
Q Consensus       705 L~aLsnL~~~~  715 (747)
                      +.++..+....
T Consensus       277 ~~~l~~l~~~~  287 (890)
T 1QBK_B          277 CEFWLTLAEQP  287 (890)
T ss_pred             HHHHHHHhcCh
Confidence            88888887653


No 465
>3W3W_A Importin subunit beta-3, Protein STE12; HEAT repeat, nuclear import, PROTEIN; 2.2A {Saccharomyces cerevisiae}
Probab=73.86  E-value=0.24  Score=53.17  Aligned_cols=153  Identities=16%  Similarity=0.154  Sum_probs=90.7  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      .++.+...+. +.++.++..++.+|..++.....     .... .-..+++.+...+.+.++.++..++.++..++.. .
T Consensus       357 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  429 (1078)
T 3W3W_A          357 LFQYLQQMIT-STEWRERFAAMMALSSAAEGCAD-----VLIG-EIPKILDMVIPLINDPHPRVQYGCCNVLGQISTDFS  429 (1078)
T ss_dssp             HHHHHHHHHT-CSCHHHHHHHHHHHHHHTTTTHH-----HHTT-CHHHHHHHHGGGGGCSSHHHHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhccHH-----HHHh-hHHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHhcc
Confidence            4455555555 35677888888888888764221     1111 1135666677777777788999999999998865 1


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      .. .......+++.+...+.+.     .+..++..++.+|..++..... ..... -..++..+...+.+. +..++..+
T Consensus       430 ~~~~~~~~~~~~~~l~~~l~~~-----~~~~~r~~a~~~l~~l~~~~~~~~~~~~-~~~i~~~l~~~l~~~-~~~~~~~~  502 (1078)
T 3W3W_A          430 PFIQRTAHDRILPALISKLTSE-----CTSRVQTHAAAALVNFSEFASKDILEPY-LDSLLTNLLVLLQSN-KLYVQEQA  502 (1078)
T ss_dssp             THHHHHHHHHHHHHHHHHTSTT-----SCHHHHHHHHHHHHHHHHTCCHHHHGGG-HHHHHHHHHHHHTCS-SHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHcccC-----CCHHHHHHHHHHHHHHHhcCChhhHHHH-HHHHHHHHHHHHhcC-CHHHHHHH
Confidence            11 1011123555555555431     2567788888888888764321 11111 123455666666544 56677777


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.++..++..
T Consensus       503 ~~~l~~l~~~  512 (1078)
T 3W3W_A          503 LTTIAFIAEA  512 (1078)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHH
Confidence            7777776643


No 466
>1IBR_B RAN  IMPORTIN BETA SUBUNIT; SMALL GTPASE  NUCLEAR TRANSPORT; HET: GNP; 2.3A {Homo sapiens} SCOP: a.118.1.1
Probab=73.63  E-value=0.25  Score=47.09  Aligned_cols=158  Identities=12%  Similarity=0.052  Sum_probs=89.8  Template_Neff=12.900

Q NP_000290.2     547 DAIRTYLNLMGKS-KKDATLEACAGALQNLTASKGLMSS------G-MSQLIGLKEKGLPQIARLLQSGNSDVVRSGASL  618 (747)
Q Consensus       547 G~I~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s~~~s~------~-~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~a  618 (747)
                      +.++.++.++.+. .++.++..|+.+|.++...... ..      . .....-....+.+.++..+.+. +.++..++.+
T Consensus        35 ~~~~~l~~~l~~~~~~~~vr~~a~~~l~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~i~~~l~~~l~~~-~~~~~~~~~~  112 (462)
T 1IBR_B           35 TFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDP-DIKAQYQQRWLAIDANARREVKNYVLQTLGTE-TYRPSSASQC  112 (462)
T ss_dssp             HHHHHHHHHHHCTTSCHHHHHHHHHHHHHHHCCSSH-HHHHHHHHHHHTSCHHHHHHHHHHHHHHTTCC-CSSSCSHHHH
T ss_pred             HHHHHHHHHHhCCCCCHHHHHHHHHHHHHHhhcCCH-HHHHHHHHhHhcCCHHHHHHHHHHHHHHHCCC-CCChhHHHHH
Confidence            4566677777621 3567888888888887653210 00      0 0000001123445555555442 3457777788


Q NP_000290.2     619 LSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNS--EDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA  696 (747)
Q Consensus       619 LsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d--~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~  696 (747)
                      ++.++...... .....+++.+...+.+      .+  +.++..++.+|..+...............+++.+...+.+. 
T Consensus       113 l~~l~~~~~~~-~~~~~~~~~l~~~l~~------~~~~~~~~~~~l~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-  184 (462)
T 1IBR_B          113 VAGIACAEIPV-NQWPELIPQLVANVTN------PNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKE-  184 (462)
T ss_dssp             HHHHHHHHGGG-TCCTTHHHHHHHHHHC------TTCCHHHHHHHHHHHHHHHHHSCGGGTGGGHHHHHHHHHHHHSTT-
T ss_pred             HHHHHhhcCCh-hhcccHHHHHHHHhhC------CCCchHHHHHHHHHHHHHhhcCCHHHHHHHHHHHHHHHHHHHhCC-
Confidence            88777541110 0112356666666665      23  67888899999888764322111111224567777777765 


Q NP_000290.2     697 S--PKAAEAARLLLSDMWSS  714 (747)
Q Consensus       697 d--~eVr~aAL~aLsnL~~~  714 (747)
                      +  ..++..++.++..++..
T Consensus       185 ~~~~~vr~~a~~~l~~l~~~  204 (462)
T 1IBR_B          185 EPSNNVKLAATNALLNSLEF  204 (462)
T ss_dssp             CCCHHHHHHHHHHHHHHTTT
T ss_pred             CCCHHHHHHHHHHHHHHHHH
Confidence            4  78889999999888654


No 467
>5VCH_A Kap123; Bidding yeast karyopherin, 23 HEAT; HET: MSE; 2.35A {Kluyveromyces lactis}
Probab=73.42  E-value=0.26  Score=53.37  Aligned_cols=153  Identities=15%  Similarity=0.124  Sum_probs=92.7  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      .++.+...+. +.++.++..++.+|..++.....     ..... -..+++.+...+.+.++.++..++.++..++... 
T Consensus       361 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  433 (1116)
T 5VCH_A          361 IIEHLPTMLS-SSNPFERRSILLAISVLVTGSPD-----YTLSQ-FDKIIPATVTGLKDSEAVVQLAALKCIVQLSTNLQ  433 (1116)
T ss_dssp             HHHHHHHHHH-CSCHHHHHHHHHHHHHHTTTCHH-----HHHHT-HHHHHHHHHHHHTCSSHHHHHHHHHHHHHHHHHSH
T ss_pred             HHHHHHHHhh-CCCHHHHHHHHHHHHHHHhcCHH-----HHHHh-HHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHhcH
Confidence            4555566665 35677788888888888764321     11111 1356677777777777889999999999888652 


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSMLNNIINLCRS-SASPKAAEAA  704 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~giL~~Ll~LL~s-~~d~eVr~aA  704 (747)
                      .........+++.+...+...     .+..++..++.+|..++..... ...... ..+++.+...+.+ . ++.++..+
T Consensus       434 ~~~~~~~~~~~~~l~~~l~~~-----~~~~v~~~a~~~l~~l~~~~~~~~~~~~~-~~~~~~l~~~l~~~~-~~~~~~~~  506 (1116)
T 5VCH_A          434 DEVARYHEQYLPLVIDIIDSA-----KHVVIYKYATLALDGLLEFIAHNDIIKYL-DPLMNKLFQMLETQQ-SPKLRAAI  506 (1116)
T ss_dssp             HHHHTTHHHHHHHHHHHHHTC-----CSHHHHHHHHHHHHHHHHTSCHHHHHHHH-HHHHHHHHHHHHHCC-CHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHhccC-----CCHHHHHHHHHHHHHHHhhCCHhhHHHHH-HHHHHHHHHHHhcCC-CHHHHHHH
Confidence            111111123555566665541     2567788888888888764222 111111 2356666666665 3 56777778


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.++..++..
T Consensus       507 ~~~l~~l~~~  516 (1116)
T 5VCH_A          507 VSAIGSCAFA  516 (1116)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHH
Confidence            8888777653


No 468
>6QH7_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: SEP; 3.4A {Rattus norvegicus}
Probab=73.36  E-value=0.26  Score=49.97  Aligned_cols=69  Identities=16%  Similarity=0.194  Sum_probs=49.2  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLM--GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL--~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+...+  . +.++.++..++.+|..+....+.        .......++.|..++.+.++.++..++.+|..+...
T Consensus       147 l~~~l~~~l~~~-~~~~~vr~~a~~~L~~~~~~~~~--------~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  217 (621)
T 6QH7_A          147 FAGEIPKILVAG-DTMDSVKQSAALCLLRLYRTSPD--------LVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQK  217 (621)
T ss_dssp             HTTHHHHHHTTS-CCCHHHHHHHHHHHHHHHHHCGG--------GCCCCTTHHHHHHGGGCSSHHHHHHHHHHHHHHHTT
T ss_pred             HHhhHHHHHHcC-CCCHHHHHHHHHHHHHHHHHChh--------hcCccchHHHHHHHhcCCCHHHHHHHHHHHHHHHHh
Confidence            455566666  5 46778888999999988764221        111245677788888888888999999999888764


No 469
>2JKT_A AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ALTERNATIVE SPLICING, PHOSPHOPROTEIN, PHOSPHORYLATION, PROTEIN; HET: SEP, SO4; 3.4A {MUS MUSCULUS}
Probab=73.28  E-value=0.27  Score=49.85  Aligned_cols=69  Identities=16%  Similarity=0.194  Sum_probs=49.0  Template_Neff=12.300

Q NP_000290.2     548 AIRTYLNLM--GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL--~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+...+  . +.++.++..++.+|..+....+.        .......++.|..++.+.++.++..++.+|..+...
T Consensus       147 l~~~l~~~l~~~-~~~~~vr~~a~~~L~~~~~~~~~--------~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  217 (623)
T 2JKT_A          147 FAGEIPKILVAG-DTMDSVKQSAALCLLRLYRTSPD--------LVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQK  217 (623)
T ss_dssp             HTTHHHHHHHCT-TSCHHHHHHHHHHHHHHHHHCTT--------TCCCCTHHHHHHGGGGCSSHHHHHHHHHHHHHHHTT
T ss_pred             HHHhHHHHHHcC-CCCHHHHHHHHHHHHHHHHHChh--------hcCccchHHHHHHHhcCCCHHHHHHHHHHHHHHHHH
Confidence            345566666  5 46778888999999888764221        111245677888888888888999999999888764


No 470
>1GCJ_B IMPORTIN-BETA; HEAT REPEAT MOTIF, NUCLEAR PORE-TARGETING; HET: MSE; 2.6A {Mus musculus} SCOP: a.118.1.1
Probab=73.02  E-value=0.27  Score=46.99  Aligned_cols=158  Identities=12%  Similarity=0.055  Sum_probs=87.6  Template_Neff=12.800

Q NP_000290.2     547 DAIRTYLNLMGKS-KKDATLEACAGALQNLTASKGLMSS------G-MSQLIGLKEKGLPQIARLLQSGNSDVVRSGASL  618 (747)
Q Consensus       547 G~I~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s~~~s~------~-~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~a  618 (747)
                      +.+..++..+.++ .+..++..|+.+|.++...... ..      . .....-....+.+.|+..+.+. ..++..++.+
T Consensus        41 ~~~~~l~~~l~~~~~~~~~r~~a~~~l~~~~~~~~~-~~~~~~~~~~~~l~~~~~~~l~~~l~~~l~~~-~~~r~~~~~~  118 (460)
T 1GCJ_B           41 TFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDP-DIKAQYQQRWLAIDANARREVKNYVLQTLGTE-TYRPSSASQC  118 (460)
T ss_dssp             HHHHHHHHHHSCTTSCHHHHHHHHHHHHTTTCCSSH-HHHHHHHHHHHHSCHHHHHHHHHHHHHHTTCC-CSSSCHHHHH
T ss_pred             HHHHHHHHHHhCCCCCHHHHHHHHHHHHHhccCCCH-HHHHHHHHHHHhCCHHHHHHHHHHHHHHHcCC-CCChhHHHHH
Confidence            3455666666521 2456777777888876643110 00      0 0000001233455566666543 3477778888


Q NP_000290.2     619 LSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNS--EDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA  696 (747)
Q Consensus       619 LsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d--~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~  696 (747)
                      +..++...... .....+++.+...+.+      .+  +.++..++.+|..+...............+++.+...+.+. 
T Consensus       119 l~~l~~~~~~~-~~~~~~~~~l~~~l~~------~~~~~~~~~~~l~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-  190 (460)
T 1GCJ_B          119 VAGIACAEIPV-SQWPELIPQLVANVTN------PNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKE-  190 (460)
T ss_dssp             HHHHHHHHGGG-TCCTTHHHHHHHHHHC------TTCCHHHHHHHHHHHHHHHHHSCHHHHGGGHHHHHHHHHHHHCTT-
T ss_pred             HHHHHHHhCCc-cccchHHHHHHHHhhC------CCCcHHHHHHHHHHHHHHhhhCCHHHhHHHHHHHHHHHHHHHhCC-
Confidence            88777541111 0112356666666665      23  67888899999888764221111111224566777777655 


Q NP_000290.2     697 S--PKAAEAARLLLSDMWSS  714 (747)
Q Consensus       697 d--~eVr~aAL~aLsnL~~~  714 (747)
                      +  ..++..++.++..+...
T Consensus       191 ~~~~~vr~~a~~~l~~~~~~  210 (460)
T 1GCJ_B          191 EPSNNVKLAATNALLNSLEF  210 (460)
T ss_dssp             CSCHHHHHHHHHHHHHHTTT
T ss_pred             CCCHHHHHHHHHHHHHHHHH
Confidence            4  78888888888887653


No 471
>1OYZ_A X-RAY STRUCTURE OF YB61_HAEIN NORTHEAST; STRUCTURAL GENOMICS, PSI, Protein Structure; 2.1A {Escherichia coli} SCOP: a.118.1.16
Probab=72.96  E-value=0.27  Score=43.42  Aligned_cols=121  Identities=14%  Similarity=0.056  Sum_probs=74.4  Template_Neff=12.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.+...+. +.++.++..++.++..+....              ...++.+...+.+.++.++..++.+|..+... 
T Consensus       159 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~--------------~~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~~-  222 (280)
T 1OYZ_A          159 ATIPLLINLLK-DPNGDVRNWAAFAININKYDN--------------SDIRDCFVEMLQDKNEEVRIEAIIGLSYRKDK-  222 (280)
T ss_dssp             CCHHHHHHHHT-CSSHHHHHHHHHHHHHHTCCC--------------HHHHHHHHHHTTCSCHHHHHHHHHHHHHTTCG-
T ss_pred             hhHHHHHHHHc-CCCHHHHHHHHHHHHhhcCCC--------------hHHHHHHHHHhcCCCHHHHHHHHHHHhccCCh-
Confidence            34566677776 356677777777776553321              13455566667777778888888888776532 


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                              ..++.+...+.+        +.++..++.+|..+...           ..++.|...+.+..++.++..++.
T Consensus       223 --------~~~~~l~~~l~~--------~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~~~~~vr~~a~~  275 (280)
T 1OYZ_A          223 --------RVLSVLCDELKK--------NTVYDDIIEAAGELGDK-----------TLLPVLDTMLYKFDDNEIITSAID  275 (280)
T ss_dssp             --------GGHHHHHHHHTS--------SSCCHHHHHHHHHHCCG-----------GGHHHHHHHHTTSSCCHHHHHHHH
T ss_pred             --------hHHHHHHHHhCC--------ccHHHHHHHHHHHhcch-----------hHHHHHHHHHhcCCCHHHHHHHHH
Confidence                    234444455543        25677777777776531           245566666665226677888877


Q NP_000290.2     707 LLSD  710 (747)
Q Consensus       707 aLsn  710 (747)
                      +|..
T Consensus       276 ~l~~  279 (280)
T 1OYZ_A          276 KLKR  279 (280)
T ss_dssp             HHTC
T ss_pred             HHhc
Confidence            7764


No 472
>2JKT_A AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ALTERNATIVE SPLICING, PHOSPHOPROTEIN, PHOSPHORYLATION, PROTEIN; HET: SEP, SO4; 3.4A {MUS MUSCULUS}
Probab=72.80  E-value=0.28  Score=49.69  Aligned_cols=67  Identities=12%  Similarity=0.101  Sum_probs=35.9  Template_Neff=12.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-s~d~eVr~~AL~aLsnLa  623 (747)
                      .++.+..++. +.+..++..++.+|..+......      ...  -...++.++..+. +.++.++..++.+|..+.
T Consensus       330 ~~~~l~~~l~-~~~~~vr~~a~~~L~~l~~~~~~------~~~--~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~  397 (623)
T 2JKT_A          330 ACNQLGQFLQ-HRETNLRYLALESMCTLASSEFS------HEA--VKTHIETVINALKTERDVSVRQRAVDLLYAMC  397 (623)
T ss_dssp             HHHHHHHHHH-SSCSHHHHHHHHHHHHHTTCSSS------CSG--GGGGHHHHHHHHHHCCSHHHHHHHHHHHHTTC
T ss_pred             HHHHHHHHhh-CCCchHHHHHHHHHHHHHcCcCC------HHH--HHHHHHHHHHHHhcCCCHHHHHHHHHHHHHhc
Confidence            3455556665 35566677777777766643210      011  1123445555555 555666666666666653


No 473
>5VE8_B Kap123, Histone H3; Bidding yeast karyopherin, 23 HEAT; HET: MSE; 2.7A {Kluyveromyces lactis}
Probab=72.66  E-value=0.27  Score=53.10  Aligned_cols=153  Identities=15%  Similarity=0.129  Sum_probs=92.5  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.+|..++.....     ..... -..+++.+...+.+.++.++..++.++..++....
T Consensus       361 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  433 (1116)
T 5VE8_B          361 IIEHLPTMLS-SSNPFERRSILLAISVLVTGSPD-----YTLSQ-FDKIIPATVTGLKDSEAVVQLAALKCIVQLSTNLQ  433 (1116)
T ss_dssp             HHHTHHHHHH-CSCHHHHHHHHHHHHHHHHHCHH-----HHHHT-HHHHHHHHHHHHTCSSHHHHHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHhh-CCCHHHHHHHHHHHHHHHhCCHH-----HHHHh-HHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHhcH
Confidence            4555555665 35677788888888888764321     11111 13566777777777788899999999999886521


Q NP_000290.2     628 -LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSMLNNIINLCRS-SASPKAAEAA  704 (747)
Q Consensus       628 -~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~giL~~Ll~LL~s-~~d~eVr~aA  704 (747)
                       ........+++.+...+...     .+..++..++.+|..++...+. ...... ..+++.+...+.+ . ++.++..+
T Consensus       434 ~~~~~~~~~~~~~l~~~l~~~-----~~~~v~~~a~~~l~~l~~~~~~~~~~~~~-~~~~~~l~~~l~~~~-~~~~~~~~  506 (1116)
T 5VE8_B          434 DEVARYHEQYLPLVIDIIDSA-----KHVVIYKYATLALDGLLEFIAHNDIIKYL-DPLMNKLFQMLETQQ-SPKLRAAI  506 (1116)
T ss_dssp             HHHHTTHHHHHHHHHHHHHTC-----CSHHHHHHHHHHHHHHHHTSCHHHHHHHH-HHHHHHHHHHHHHCC-CHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHhccC-----CCHHHHHHHHHHHHHHHhhcCHhhHHHHH-HHHHHHHHHHHhcCC-CHHHHHHH
Confidence             11111123555666665541     2567788888888888764222 111111 2356666666665 3 56777778


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.++..++..
T Consensus       507 ~~~l~~l~~~  516 (1116)
T 5VE8_B          507 VSAIGSCAFA  516 (1116)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHH
Confidence            8888777653


No 474
>4ZV6_A AlphaRep-7, Octarellin V.1; synthetic gene, artificial protein, Rossmann-like; 2.22A {synthetic construct}
Probab=71.73  E-value=0.3  Score=43.65  Aligned_cols=29  Identities=17%  Similarity=0.240  Sum_probs=18.6  Template_Neff=12.500

Q NP_000290.2     685 LNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       685 L~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.+...+.+. ++.++..++.++..+...
T Consensus       140 ~~~l~~~l~~~-~~~~r~~a~~~l~~~~~~  168 (294)
T 4ZV6_A          140 VEPLIKALKDE-DPYVRMAAAYALGKIGDE  168 (294)
T ss_pred             HHHHHHHhCCC-CHHHHHHHHHHHhhhCCH
Confidence            34455555554 667788888888776543


No 475
>6BZX_A alpha-Rep, Octarellin V.1; protein design, artificial protein, DE; 3.107A {synthetic construct}
Probab=71.39  E-value=0.31  Score=43.56  Aligned_cols=29  Identities=17%  Similarity=0.240  Sum_probs=18.5  Template_Neff=12.500

Q NP_000290.2     685 LNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       685 L~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.+...+.+. ++.++..++.++..+...
T Consensus       140 ~~~l~~~l~~~-~~~~r~~a~~~l~~~~~~  168 (294)
T 6BZX_A          140 VEPLIKALKDE-DPYVRMAAAYALGKIGDE  168 (294)
T ss_dssp             HHHHHHHTTCS-SHHHHHHHHHHHHHHTCG
T ss_pred             HHHHHHHhcCC-CHHHHHHHHHHHHHHcch
Confidence            34455555554 667788888887776543


No 476
>5IFE_C Splicing factor 3B subunit 5; pre-mRNA splicing, U2 snRNP, essential; 3.1A {Homo sapiens}
Probab=70.42  E-value=0.38  Score=55.84  Aligned_cols=154  Identities=9%  Similarity=0.047  Sum_probs=91.7  Template_Neff=9.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      +++.|...+.+..++.++..++.+|..++.....     .... .-..+++.|...+.+.+..++..++.+|..++... 
T Consensus       644 ll~~L~~~l~s~~~~~~r~~al~~L~~l~~~~~~-----~~~~-~l~~ll~~L~~~L~d~~~~VR~~a~~~L~~l~~~~~  717 (1304)
T 5IFE_C          644 LLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGC-----AILP-HLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAAT  717 (1304)
T ss_pred             HHHHHHHHHcCCCCHHHHHHHHHHHHHHHHHhhh-----hchh-hHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhCC
Confidence            4455555555222367788888888888753221     0111 11345666777777777889999999999988652 


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. ...+ ..+++.|+..+.+      ....++..++.+|..++..............++..|...+.+. +..++..++
T Consensus       718 ~~~~~~~-~~ll~~Ll~~l~~------~~~~v~~~~l~aL~~l~~~~~~~~~~~~~~~ll~~L~~~l~~~-~~~vr~~al  789 (1304)
T 5IFE_C          718 PYGIESF-DSVLKPLWKGIRQ------HRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSP-DEEMKKIVL  789 (1304)
T ss_pred             HHHHHHH-HHHHHHHHHHHhc------CCHHHHHHHHHHHHHHHHhcCHHHhhhHHHHHHHHHHHHhCCC-CHHHHHHHH
Confidence            11 1111 2345666666654      2456677788888877653221111111124566666777655 677888888


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .+|..++...
T Consensus       790 ~~L~~l~~~~  799 (1304)
T 5IFE_C          790 KVVKQCCGTD  799 (1304)
T ss_pred             HHHHHHHhcc
Confidence            8888877543


No 477
>6AHD_1 Pre-mRNA-processing-splicing factor 8, Thioredoxin-like protein; Spliceosome, SPLICING; HET: IHP, GTP; 3.8A {Homo sapiens}
Probab=70.42  E-value=0.38  Score=55.84  Aligned_cols=154  Identities=9%  Similarity=0.047  Sum_probs=91.7  Template_Neff=9.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      +++.|...+.+..++.++..++.+|..++.....     .... .-..+++.|...+.+.+..++..++.+|..++... 
T Consensus       644 ll~~L~~~l~s~~~~~~r~~al~~L~~l~~~~~~-----~~~~-~l~~ll~~L~~~L~d~~~~VR~~a~~~L~~l~~~~~  717 (1304)
T 6AHD_1          644 LLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGC-----AILP-HLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAAT  717 (1304)
T ss_pred             HHHHHHHHHcCCCCHHHHHHHHHHHHHHHHHhhh-----hchh-hHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhCC
Confidence            4455555555222367788888888888753221     0111 11345666777777777889999999999988652 


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. ...+ ..+++.|+..+.+      ....++..++.+|..++..............++..|...+.+. +..++..++
T Consensus       718 ~~~~~~~-~~ll~~Ll~~l~~------~~~~v~~~~l~aL~~l~~~~~~~~~~~~~~~ll~~L~~~l~~~-~~~vr~~al  789 (1304)
T 6AHD_1          718 PYGIESF-DSVLKPLWKGIRQ------HRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSP-DEEMKKIVL  789 (1304)
T ss_pred             HHHHHHH-HHHHHHHHHHHhc------CCHHHHHHHHHHHHHHHHhcCHHHhhhHHHHHHHHHHHHhCCC-CHHHHHHHH
Confidence            11 1111 2345666666654      2456677788888877653221111111124566666777655 677888888


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .+|..++...
T Consensus       790 ~~L~~l~~~~  799 (1304)
T 6AHD_1          790 KVVKQCCGTD  799 (1304)
T ss_pred             HHHHHHHhcc
Confidence            8888877543


No 478
>2QK2_A LP04448p; Mini spindles, Msps, XMAP215, Dis1; 2.1A {Drosophila melanogaster}
Probab=70.35  E-value=0.34  Score=41.59  Aligned_cols=113  Identities=7%  Similarity=-0.008  Sum_probs=66.2  Template_Neff=12.700

Q NP_000290.2     243 SGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLL-RSPNQNVQQAAAGALRNLVFRSTTN  321 (747)
Q Consensus       243 ~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL-~s~d~eVr~~AL~aLs~La~~~~~~  321 (747)
                      ...+++.+...+.+.++.++..++..+..+....+....... ..+++.+...+ .+.++.++..++.++..+.......
T Consensus        13 ~~~l~~~l~~~l~~~~~~~r~~a~~~l~~~~~~~~~~~~~~~-~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~~~~~~~   91 (242)
T 2QK2_A           13 LSKMPKDFYDKLEEKKWTLRKESLEVLEKLLTDHPKLENGEY-GALVSALKKVITKDSNVVLVAMAGKCLALLAKGLAKR   91 (242)
T ss_dssp             GGGSCTTHHHHHTCSSHHHHHHHHHHHHHHHHHCSSBCCCCC-HHHHHHHHHHHHHCSCHHHHHHHHHHHHHHHHHHGGG
T ss_pred             hhhCCHHHHHHHhccchHHHHHHHHHHHHHHhhCcccccchH-HHHHHHHHHHHccCcHHHHHHHHHHHHHHHHHHhhHh
Confidence            344555666667777788888999988888764332111111 23566666667 6667788888888888877543322


Q NP_000290.2     322 KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       322 ~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      .... ...+++.+...+. +.+..++..+..++..+.
T Consensus        92 ~~~~-~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~  126 (242)
T 2QK2_A           92 FSNY-ASACVPSLLEKFK-EKKPNVVTALREAIDAIY  126 (242)
T ss_dssp             GHHH-HHHHHHHHHHGGG-CCCHHHHHHHHHHHHHHH
T ss_pred             HHHH-HHhHHHHHHHHHh-cCCHHHHHHHHHHHHHHH
Confidence            1111 1234555555554 334455555555555544


No 479
>6MZG_E Tubulin alpha-1A chain, Tubulin beta; Microtubule, Tubulin, Tubulin polymerization, Heat; HET: GTP, GDP; 3.208A {Sus scrofa}
Probab=70.02  E-value=0.35  Score=47.53  Aligned_cols=71  Identities=15%  Similarity=0.238  Sum_probs=44.3  Template_Neff=12.700

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQ---LIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~---~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ++.++..+. +.++.++..++.+|..++.....   . ..   .. ....+++.+..++.+.++.++..++.+|..+...
T Consensus       138 ~~~l~~~l~-~~~~~vr~~~~~~l~~l~~~~~~---~-~~~~~~~-~~~~i~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  211 (554)
T 6MZG_E          138 VNLMLPSLS-NKLPRLVSSCVKCLATIIEEFGF---I-NVSDINI-LLSEILEPLPKLSSHADRNVRSETMNLILQIYKW  211 (554)
T ss_dssp             HHHHSGGGG-CSCHHHHHHHHHHHHHHHHHTCS---C-SCSCHHH-HHHHHHSSHHHHTTCSSHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHhc-CCCHHHHHHHHHHHHHHHHHhCC---C-ccccccc-cHHHHHHHHHHHhhcCCHHHHHHHHHHHHHHHHH
Confidence            444555555 35667777888888877653221   0 00   00 1235667777777777788888888888877654


No 480
>6QH7_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: SEP; 3.4A {Rattus norvegicus}
Probab=69.91  E-value=0.36  Score=48.86  Aligned_cols=100  Identities=18%  Similarity=0.054  Sum_probs=56.7  Template_Neff=12.200

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETR  326 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll  326 (747)
                      ++.+...+.+.++.++..++.++..+........     ..++..+...+.+.++.++..++.++..+....       .
T Consensus        76 ~~~l~~~l~~~~~~~r~~a~~~l~~~~~~~~~~~-----~~~~~~l~~~l~~~~~~vr~~al~~l~~~~~~~-------~  143 (621)
T 6QH7_A           76 HMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELI-----RLINNAIKNDLASRNPTFMGLALHCIANVGSRE-------M  143 (621)
T ss_dssp             HHHHHHHTTCSSHHHHHHHHHHHHHSCCCCHHHH-----HHHHHHHHHHHHSCCHHHHHHHHHHHHHHCCHH-------H
T ss_pred             HHHHHHHHcCCCccHHHHHHHHHHHHcCCCHHHH-----HHHHHHHHHHHhcCCHHHHHHHHHHHHhhCCHH-------H
Confidence            3344455555666677777777776654322111     123444555555666777777777777665321       0


Q NP_000290.2     327 RQNGIREAVSLL--RRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       327 ~~~IL~~Ll~lL--~ss~d~eVr~~AL~aLsnLas  359 (747)
                      ...++..+...+  . +.++.++..++.++..+..
T Consensus       144 ~~~l~~~l~~~l~~~-~~~~~vr~~a~~~L~~~~~  177 (621)
T 6QH7_A          144 AEAFAGEIPKILVAG-DTMDSVKQSAALCLLRLYR  177 (621)
T ss_dssp             HHHHTTHHHHHHTTS-CCCHHHHHHHHHHHHHHHH
T ss_pred             HHHHHhhHHHHHHcC-CCCHHHHHHHHHHHHHHHH
Confidence            113444455555  4 4566777788888777765


No 481
>1UKL_A Importin beta-1 subunit/Sterol regulatory element; Transcription factor, Nuclear transport factor; HET: MSE; 3.0A {Mus musculus} SCOP: a.118.1.1
Probab=69.90  E-value=0.35  Score=50.26  Aligned_cols=154  Identities=11%  Similarity=0.064  Sum_probs=87.3  Template_Neff=13.100

Q NP_000290.2     548 AIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsnLa  623 (747)
                      .++.+...+. +.+  +.++..++.+|..+......   . .... ....+++.+...+.+.+  +.++..++.++..+.
T Consensus       129 l~~~l~~~l~-~~~~~~~~~~~al~~l~~l~~~~~~---~-~~~~-~~~~l~~~l~~~l~~~~~~~~vr~~a~~~l~~~~  202 (876)
T 1UKL_A          129 LIPQLVANVT-NPNSTEHMKESTLEAIGYICQDIDP---E-QLQD-KSNEILTAIIQGMRKEEPSNNVKLAATNALLNSL  202 (876)
T ss_dssp             SHHHHHHHHH-STTCCHHHHHHHHHHHHHHHHHSCS---T-TTSS-SCHHHHHHHHHTTSTTCSCHHHHHHHHHHHHHHG
T ss_pred             HHHHHHHHhh-CCCCCHHHHHHHHHHHHHHhccCCH---H-HHHH-HHHHHHHHHHHHHhCCCCCHHHHHHHHHHHHHHH
Confidence            3455555565 233  56777788888777653221   0 0001 12346666777776655  778888888888876


Q NP_000290.2     624 RH-PLL-H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       624 ~~-~e~-~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      .. ... . ......++..+..++.+      .++.++..++.+|..+....+..........+++.+...+.+. ++.+
T Consensus       203 ~~~~~~~~~~~~~~~~~~~l~~~~~~------~~~~~r~~a~~~l~~l~~~~~~~~~~~~~~~l~~~l~~~l~~~-~~~v  275 (876)
T 1UKL_A          203 EFTKANFDKESERHFIMQVVCEATQC------PDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSD-IDEV  275 (876)
T ss_dssp             GGCHHHHHSHHHHHHHHHHHHHHTTS------SCHHHHHHHHHHHHHHHTTCGGGGHHHCCCCCHHHHHHHHHCS-CHHH
T ss_pred             HHhHHhcCCHHHHHHHHHHHHHHhCC------CCHHHHHHHHHHHHHHHHHHHHHhHHhchHHHHHHHHHHhhCC-CHHH
Confidence            54 111 0 01112233334444443      3577888899999888765333222122223456666666655 6778


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..+...
T Consensus       276 ~~~a~~~l~~l~~~  289 (876)
T 1UKL_A          276 ALQGIEFWSNVCDE  289 (876)
T ss_dssp             HHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH
Confidence            88888888777653


No 482
>6EMK_C Serine/threonine-protein kinase TOR2 (E.C.2.7.1.67,2.7.11.1), Target; target of rapamycin, torc2, FRB; 8.0A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=69.88  E-value=0.38  Score=58.82  Aligned_cols=136  Identities=10%  Similarity=0.088  Sum_probs=72.9  Template_Neff=11.300

Q NP_000290.2     562 DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEV  640 (747)
Q Consensus       562 ~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~L  640 (747)
                      +.++..++.+|..++.....   . ....  -..+++.|...+.+....++..+..++..+...... ...+ ..+++.+
T Consensus      1016 ~~vr~~a~~~l~~l~~~~~~---~-~~~~--~~~ll~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~l-~~i~~~l 1088 (2474)
T 6EMK_C         1016 IKLQITIISVIESISKALEG---E-FKRF--VPETLTFFLDILENDQSNKRIVPIRILKSLVTFGPNLEDYS-HLIMPIV 1088 (2474)
T ss_dssp             CCCCCCCSSCCCCCCSSCSC---C-SCCC--CCCCCTTHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCC-CCCTTHH
T ss_pred             hHHHHHHHHHHHHHHHHhhH---h-HHHH--HHHHHHHHHHHHhcCCCCCcchHHHHHHHHHHhhhhHHHHH-HHHHHHH
Confidence            34555666666666543221   0 0111  134556666666655445555555565555533111 1111 2244555


Q NP_000290.2     641 TRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       641 l~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      +..+..      .++.++..++.+|..++.....  .. ....++..+...+.+. ++.++..++.+|..++..
T Consensus      1089 ~~~l~~------~~~~vr~~a~~~l~~l~~~~~~--~~-~~~~i~~~l~~~l~~~-~~~vr~~a~~~l~~l~~~ 1152 (2474)
T 6EMK_C         1089 VRMTEY------SAGSLKKISIITLGRLAKNINL--SE-MSSRIVQALVRILNNG-DRELTKATMNTLSLLLLQ 1152 (2474)
T ss_dssp             HHCCCC------CCCCCTTTTTCCCCCCCCCCCC--CC-CCCCCCCCCCSCCCCC-CCCSSHHHHTTTCCGGGC
T ss_pred             HHHhcC------CCccHHHHHHHHHHHHHHhCCh--HH-HHHHHHHHHHHHHhcC-CHHHHHHHHHHHHHHHHH
Confidence            555554      2567888888888888754221  11 1123566666666654 667788888888777653


No 483
>4XL5_C Green fluorescent protein, bGFP-A; AlphaRep Scaffold, Complex, EGFP, PROTEIN; HET: CRO; 2.0A {Aequorea victoria}
Probab=69.87  E-value=0.36  Score=42.43  Aligned_cols=49  Identities=10%  Similarity=0.082  Sum_probs=29.3  Template_Neff=12.400

Q NP_000290.2     654 SEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       654 d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.++..++.++..+..           ...++.+..++.+. ++.++..++.++..+...
T Consensus       120 ~~~~~~~a~~~l~~~~~-----------~~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~~~  168 (263)
T 4XL5_C          120 DPWVRLTAARALGEIGD-----------ERAVEPLIKALKDE-DPWVRLTAARALGQIGDE  168 (263)
T ss_dssp             SHHHHHHHHHHHHHHCC-----------GGGHHHHHHHTTCS-SHHHHHHHHHHHHHHCCG
T ss_pred             CHHHHHHHHHHHHHHCC-----------hhhHHHHHHHhhCC-CHHHHHHHHHHHHhhCCH
Confidence            34455555555554432           12345555666655 678888888888877653


No 484
>4D4Z_A DEOXYHYPUSINE HYDROXYLASE (E.C.1.14.99.29); OXIDOREDUCTASE, EIF-5A, HYPUSINE; HET: B3P, GOL; 1.7A {HOMO SAPIENS}
Probab=69.81  E-value=0.36  Score=42.88  Aligned_cols=127  Identities=10%  Similarity=0.093  Sum_probs=78.7  Template_Neff=12.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDA--TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~e--Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++.|...+. +.+..  ++..++.+|..+..                ...++.+...+.+.++.++..++.+|..+..
T Consensus       161 ~~~~~l~~~l~-~~~~~~~~r~~a~~~l~~~~~----------------~~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~  223 (294)
T 4D4Z_A          161 RDVGRLREALL-DESRPLFERYRAMFALRNAGG----------------EEAALALAEGLHCGSALFRHEVGYVLGQLQH  223 (294)
T ss_dssp             CCHHHHHHHHH-CTTSCHHHHHHHHHHHHHHCH----------------HHHHHHHHHGGGSSCHHHHHHHHHHHHHHCC
T ss_pred             HHHHHHHHHHH-hCCCCHHHHHHHHHHHHHcCC----------------HHHHHHHHHHhcCCCHHHHHHHHHHHHhcCC
Confidence            34566667776 34433  66677777665532                1234455666667777888888888877653


Q NP_000290.2     625 HPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       625 ~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      .         ..++.+...+.+.    ..++.++..++.+|+.+...           ..++.|..++.+. ++.++..+
T Consensus       224 ~---------~~~~~l~~~l~~~----~~~~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~vr~~a  278 (294)
T 4D4Z_A          224 E---------AAVPQLAAALARC----TENPMVRHECAEALGAIARP-----------ACLAALQAHADDP-ERVVRESC  278 (294)
T ss_dssp             G---------GGHHHHHHHHHCT----TSCHHHHHHHHHHHHHHCCH-----------HHHHHHHHHTTCS-SHHHHHHH
T ss_pred             h---------hHHHHHHHHHHhC----CCCHHHHHHHHHHHHHhccH-----------HHHHHHHHHhcCC-ChHHHHHH
Confidence            2         2344455555520    02567888888888876531           2455666667655 67788888


Q NP_000290.2     705 RLLLSDMWSSK  715 (747)
Q Consensus       705 L~aLsnL~~~~  715 (747)
                      +.+|..+....
T Consensus       279 ~~~l~~~~~~~  289 (294)
T 4D4Z_A          279 EVALDMYEHET  289 (294)
T ss_dssp             HHHHHHHHHC-
T ss_pred             HHHHHHHHhhc
Confidence            88888776443


No 485
>4D50_A DEOXYHYPUSINE HYDROXYLASE (E.C.1.14.99.29); OXIDOREDUCTASE; HET: GAI; 1.7A {HOMO SAPIENS}
Probab=69.81  E-value=0.36  Score=42.88  Aligned_cols=127  Identities=10%  Similarity=0.093  Sum_probs=79.0  Template_Neff=12.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDA--TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~e--Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++.|...+. +.+..  ++..++.+|..+..                ...++.+...+.+.++.++..++.+|..+..
T Consensus       161 ~~~~~l~~~l~-~~~~~~~~r~~a~~~l~~~~~----------------~~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~  223 (294)
T 4D50_A          161 RDVGRLREALL-DESRPLFERYRAMFALRNAGG----------------EEAALALAEGLHCGSALFRHEVGYVLGQLQH  223 (294)
T ss_dssp             CCHHHHHHHHH-CTTSCHHHHHHHHHHHHHHCS----------------HHHHHHHHHGGGSSCHHHHHHHHHHHHHHCC
T ss_pred             HHHHHHHHHHH-hCCCCHHHHHHHHHHHHHcCC----------------HHHHHHHHHHhcCCCHHHHHHHHHHHHhcCC
Confidence            34566667776 34433  66677777665532                1234455666667777888888888877653


Q NP_000290.2     625 HPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       625 ~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      .         ..++.+...+.+.    ..++.++..++.+|+.+...           ..++.|..++.+. ++.++..+
T Consensus       224 ~---------~~~~~l~~~l~~~----~~~~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~vr~~a  278 (294)
T 4D50_A          224 E---------AAVPQLAAALARC----TENPMVRHECAEALGAIARP-----------ACLAALQAHADDP-ERVVRESC  278 (294)
T ss_dssp             G---------GGHHHHHHHHHCT----TSCHHHHHHHHHHHHHHCCH-----------HHHHHHHHTTTCS-CHHHHHHH
T ss_pred             h---------hHHHHHHHHHHhC----CCCHHHHHHHHHHHHHhccH-----------HHHHHHHHHhcCC-ChHHHHHH
Confidence            2         2344455555520    02567888888888876531           2455666667655 67788888


Q NP_000290.2     705 RLLLSDMWSSK  715 (747)
Q Consensus       705 L~aLsnL~~~~  715 (747)
                      +.+|..+....
T Consensus       279 ~~~l~~~~~~~  289 (294)
T 4D50_A          279 EVALDMYEHET  289 (294)
T ss_dssp             HHHHHHHHHHH
T ss_pred             HHHHHHHHhhc
Confidence            88888776443


No 486
>6QH5_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=69.69  E-value=0.37  Score=48.79  Aligned_cols=67  Identities=12%  Similarity=0.101  Sum_probs=37.3  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-s~d~eVr~~AL~aLsnLa  623 (747)
                      .++.+..++. +.++.++..++.+|..+......      ...  -...++.+...+. +.++.++..++.+|..+.
T Consensus       330 ~~~~l~~~l~-~~~~~vr~~a~~~L~~l~~~~~~------~~~--~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~  397 (621)
T 6QH5_A          330 ACNQLGQFLQ-HRETNLRYLALESMCTLASSEFS------HEA--VKTHIETVINALKTERDVSVRQRAVDLLYAMC  397 (621)
T ss_pred             HHHHHHHHHh-CCCHHHHHHHHHHHHHHHhcCCC------hhH--HHHHHHHHHHHHhcCCCHHHHHHHHHHHHHhc
Confidence            4555666665 35666777777777777653110      111  1224445555555 555666666666666653


No 487
>4XL5_C Green fluorescent protein, bGFP-A; AlphaRep Scaffold, Complex, EGFP, PROTEIN; HET: CRO; 2.0A {Aequorea victoria}
Probab=69.51  E-value=0.37  Score=42.33  Aligned_cols=88  Identities=10%  Similarity=0.162  Sum_probs=47.9  Template_Neff=12.400

Q NP_000290.2     600 IARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQY  679 (747)
Q Consensus       600 Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~L  679 (747)
                      +..++.+.++.++..++.++..+..         ...++.+...+.+      .++.++..++.+|..+..         
T Consensus       143 l~~~l~~~~~~vr~~a~~~l~~~~~---------~~~~~~l~~~l~~------~~~~~r~~a~~~l~~~~~---------  198 (263)
T 4XL5_C          143 LIKALKDEDPWVRLTAARALGQIGD---------ERAVEPLIKALKD------EDASVRKAAAVALGQIGD---------  198 (263)
T ss_dssp             HHHHTTCSSHHHHHHHHHHHHHHCC---------GGGHHHHHHHTTC------SSHHHHHHHHHHHHHHCC---------
T ss_pred             HHHHhhCCCHHHHHHHHHHHHhhCC---------HHHHHHHHHHhcC------CCHHHHHHHHHHHHHhCC---------
Confidence            3344444444555555555444432         1223344444444      245566667666666542         


Q NP_000290.2     680 FSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       680 ve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                        ...++.+..++.+. +..++..++.++..+...
T Consensus       199 --~~~~~~l~~~l~~~-~~~~~~~a~~~l~~~~~~  230 (263)
T 4XL5_C          199 --ERAVEPLIKALKDE-DEYVRQRAASALGKIGGE  230 (263)
T ss_dssp             --GGGHHHHHHHTTCS-SHHHHHHHHHHHHHHCHH
T ss_pred             --hhhHHHHHHHhcCC-CHHHHHHHHHHHHhhCcH
Confidence              12345566666655 677888888888887753


No 488
>6LTJ_L Histone H3.2, Histone H4, Histone; Chromatin remodeler, Complex, GENE REGULATION; 3.7A {Xenopus laevis}
Probab=69.20  E-value=0.52  Score=55.12  Aligned_cols=106  Identities=11%  Similarity=0.124  Sum_probs=60.8  Template_Neff=5.100

Q NP_000290.2     609 SDVVRSGASLLSNMSRHPLL---HRVMGNQVFPEVTRLLTSHTGNTSNSE----------DILSSACYTVRNLMASQPQL  675 (747)
Q Consensus       609 ~eVr~~AL~aLsnLa~~~e~---~~ll~~giI~~Ll~LL~s~s~~~~~d~----------eVr~~Al~aLsnLa~~s~e~  675 (747)
                      ..+++.++.+|.||+...+.   ...+...++..|+.++...... ..++          ..+..|+.+|+.|+.. +.+
T Consensus      1064 ~~LRenaLviLaNIAg~LdLs~~~e~I~~~ild~LLhwlv~~sa~-a~Dp~~~~~~~~~lSp~~lALEaLsKLsv~-d~N 1141 (1295)
T 6LTJ_L         1064 EMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAE-AQDPFSTLGPNAVLSPQRLVLETLSKLSIQ-DNN 1141 (1295)
T ss_dssp             HHHHHHHHHHHHHHGGGCCCSSSCHHHHHHHHHHHHHHHHCCSSS-SSSCCTTSCTTCCCCHHHHHHHHHHHHHTS-HHH
T ss_pred             HHHHHHHHHHHHHHHcccCCCCCChHhHHHHHHHHHHHHcCcChh-cCChhhccCCCCCCCHHHHHHHHHHHHhCC-Cch
Confidence            35667788889998876221   1111112455555544321000 0011          1234589999999874 555


Q NP_000290.2     676 AKQYFSSS-------MLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       676 ~~~Lve~g-------iL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      ...++...       ++..|+.+|....+..+++.++.+|.+|+...+
T Consensus      1142 ~dlLlat~p~srle~Ll~~LV~lL~~~ed~~lrE~AL~lL~~Ls~~~~ 1189 (1295)
T 6LTJ_L         1142 VDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDS 1189 (1295)
T ss_dssp             HHHHHTSSCHHHHHHHHHHHHHHHHHCSSHHHHHHHHHHHHHHHHHCH
T ss_pred             HHHHHhCCCHHHHHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHcCCH
Confidence            55555433       566667777644245678899999999987543


No 489
>5WLC_LM rpS18_uS13, rpS4_eS4, rpS5_uS7, rpS6_eS6, rpS7_eS7; Ribosome assembly, RIBOSOME; 3.8A {Saccharomyces cerevisiae BY4741}
Probab=69.09  E-value=0.44  Score=57.42  Aligned_cols=153  Identities=6%  Similarity=-0.058  Sum_probs=85.4  Template_Neff=9.300

Q NP_000290.2     548 AIRTYLNLMGKS-----KKDATLEACAGALQNLTASKGLMSSGMSQL-IGLKEKGLPQIARLLQSGNSDVVRSGASLLSN  621 (747)
Q Consensus       548 ~I~~LL~LL~ss-----~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~-llie~giI~~Ll~LL~s~d~eVr~~AL~aLsn  621 (747)
                      +++.++..+...     .+..++..++.+|..++.....   ..... .. -..+++.|...+......++..++.++..
T Consensus      1597 ll~~l~~~L~~~~~~~~~~~~v~~~al~~L~~l~~~~~~---~~~~~~~~-~~~il~~L~~~L~~~~~~v~~~al~~L~~ 1672 (1769)
T 5WLC_LM        1597 LLEPVDMLLKRFISKDMENVNLRRLVINSLTSSLKFDRD---EYWKSTSR-FELISVSLVNQLSNIENSIGKYLVKAIGA 1672 (1769)
T ss_pred             HHHHHHHHHHHhcCCchhcHHHHHHHHHHHHHHHhhCCc---ccccCHhH-HHHHHHHHHHHHHccchHHHHHHHHHHHH
Confidence            455555555421     1356677888888887764221   00000 11 13456666666666556677778888888


Q NP_000290.2     622 MSRH-PLLHRVMGNQVFPEVTRLLTSHTGNTSN-SEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPK  699 (747)
Q Consensus       622 La~~-~e~~~ll~~giI~~Ll~LL~s~s~~~~~-d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~e  699 (747)
                      ++.. ....... ..+.+.++..+.+      . +..++..++.++..+..........+. ..+++.+.+.+.+. ++.
T Consensus      1673 L~~~~~~~~~~~-~~l~~~ll~~l~~------~~~~~vR~~al~~L~~l~~~~g~~~~~~l-~~il~~L~e~Led~-~~~ 1743 (1769)
T 5WLC_LM        1673 LASNNSGVDEHN-QILNKLIVEHMKA------SCSSNEKLWAIRAMKLIYSKIGESWLVLL-PQLVPVIAELLEDD-DEE 1743 (1769)
T ss_pred             HHHhccCChHHH-HHHHHHHHHHhcC------CCCHHHHHHHHHHHHHHHHHHChhHHHhH-hHHHHHHHHHccCC-CHH
Confidence            7653 1111111 1133344444433      2 567788888898888765332211111 24567777777765 677


Q NP_000290.2     700 AAEAA-RLLLSDMWS  713 (747)
Q Consensus       700 Vr~aA-L~aLsnL~~  713 (747)
                      ++..+ ..++..+..
T Consensus      1744 Vr~~a~~~~l~~L~~ 1758 (1769)
T 5WLC_LM        1744 IEREVRTGLVKVVEN 1758 (1769)
T ss_pred             HHHHHHHHHHHHHHH
Confidence            88888 777776654


No 490
>5YVI_A Transportin-1, RNA-binding protein FUS; Importin family, PROTEIN TRANSPORT, PROTEIN; 2.9A {Homo sapiens}
Probab=69.07  E-value=0.37  Score=49.71  Aligned_cols=155  Identities=9%  Similarity=0.106  Sum_probs=91.1  Template_Neff=13.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIG--LKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~ll--ie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+...+. +.++.++..++.+|..++.....   ......+  .-..+++.+...+.+.++.++..++.+|..++..
T Consensus       131 ~~~~l~~~l~-~~~~~~~~~~l~~l~~l~~~~~~---~~~~~~~~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  206 (868)
T 5YVI_A          131 LLPKLCSLLD-SEDYNTCEGAFGALQKICEDSAE---ILDSDVLDRPLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIIS  206 (868)
T ss_dssp             HHHHHHHHHT-CSSHHHHHHHHHHHHHHHHHHTT---CSCC--CCSTHHHHHHHHGGGGGCSSHHHHHHHHHHHHTTTTT
T ss_pred             HHHHHHHHhc-CCChHHHHHHHHHHHHHHHHHhh---hcchhhccHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHh
Confidence            4555666665 35667777888888887754211   0000000  0134566677777777788888999999888765


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      ... .......+++.+...+.+      .+..++..++.+|..++........... ..+++.+...+.+. ++.++..+
T Consensus       207 ~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~-~~~v~~~~  278 (868)
T 5YVI_A          207 RTQALMLHIDSFIENLFALAGD------EEPEVRKNVCRALVMLLEVRMDRLLPHM-HNIVEYMLQRTQDQ-DENVALEA  278 (868)
T ss_dssp             TCHHHHTTHHHHHHHHHHTTTC------SSHHHHHHHHHHHHHHHHHCHHHHGGGH-HHHHHHHHHHHTCS-SHHHHHHH
T ss_pred             chHHHHHhHHHHHHHHHHHcCC------CCHHHHHHHHHHHHHHHHHcHHHHHHhH-HHHHHHHHHHccCC-CHHHHHHH
Confidence            211 111112345555555544      2567788888888888764322111111 23456666666655 67788888


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.++..++..
T Consensus       279 ~~~l~~l~~~  288 (868)
T 5YVI_A          279 CEFWLTLAEQ  288 (868)
T ss_dssp             HHHHHHHHHS
T ss_pred             HHHHHHHhcC
Confidence            8888887764


No 491
>3VWA_A Cytoplasmic export protein 1; tRNA, nuclear export, HEAT repeat; 2.2A {Saccharomyces cerevisiae}
Probab=68.93  E-value=0.42  Score=49.31  Aligned_cols=111  Identities=9%  Similarity=0.051  Sum_probs=80.6  Template_Neff=10.600

Q NP_000290.2     594 EKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP  673 (747)
Q Consensus       594 ~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~  673 (747)
                      ..+++.+..++.+.++.++..++..|..++.... .......+++.+...+.+      .+..++..++.+|..++...+
T Consensus       340 ~~~~~~l~~ll~~~~~~vR~~~~~~l~~~~~~~~-~~~~~~~~~~~l~~~l~d------~~~~vr~~a~~~l~~l~~~~~  412 (560)
T 3VWA_A          340 VGFNDLITQSFKLPDRQVRFLLLIYLPKLIGPLS-KSEISSRIYPHFIQGLTD------SDATLRLQTLKTIPCIVSCLT  412 (560)
T ss_dssp             TTHHHHHHHHHHCCCHHHHHHHHHHHHHHBTTBC-HHHCCCCCHHHHHHGGGC------SSHHHHHHHHHHHHHHGGGCC
T ss_pred             cchHHHHHHHcCCCCHHHHHHHHHhHHHHhccCC-HHHHHhchHHHHHHHhcC------CCHHHHHHHHHHHHHHHhhCC
Confidence            4577888888888888999999999888876411 112234567777777766      367889999999999886432


Q NP_000290.2     674 QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       674 e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ..   .....+++.+..++.+. ++.++..++.+|..++...
T Consensus       413 ~~---~~~~~ll~~l~~~l~d~-~~~vR~~a~~~l~~i~~~~  450 (560)
T 3VWA_A          413 ER---QLNNELLRFLAKTQVDS-DVEIRTWTVIIISKISTIL  450 (560)
T ss_dssp             HH---CCCCCCHHHHHHHTTCS-SHHHHHHHHHHHHHHGGGS
T ss_pred             HH---HHHHHHHHHHHHHcCCC-CHHHHHHHHHHHHHHHHHh
Confidence            11   22345677888888766 7899999999999887544


No 492
>3VWA_B Cytoplasmic export protein 1; tRNA, nuclear export, HEAT repeat; HET: MSE; 2.2A {Saccharomyces cerevisiae}
Probab=68.86  E-value=0.42  Score=49.21  Aligned_cols=111  Identities=9%  Similarity=0.062  Sum_probs=80.6  Template_Neff=10.700

Q NP_000290.2     594 EKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP  673 (747)
Q Consensus       594 ~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~  673 (747)
                      ..+++.+..++.+.++.++..++..|..++.... .......+++.++..+.+      .++.++..++.+|..++...+
T Consensus       340 ~~~~~~l~~l~~~~~~~vr~~~~~~l~~~~~~~~-~~~~~~~~l~~l~~~l~d------~~~~vr~~a~~~l~~l~~~~~  412 (560)
T 3VWA_B          340 VGFNDLITQSFKLPDRQVRFLLLIYLPKLIGPLS-KSEISSRIYPHFIQGLTD------SDATLRLQTLKTIPCIVSCLT  412 (560)
T ss_dssp             TTHHHHHHHHHHCCCHHHHHHHHHHHHHHBTTBC-HHHCCCCCHHHHHHGGGC------SCHHHHHHHHHHHHHHGGGSC
T ss_pred             cchHHHHHHHcCCCcHHHHHHHHHhHHHHhhhCC-HHHHhhchHHHHHHHhcC------CCHHHHHHHHHHHHHHHhhCC
Confidence            4577888888888888899999998888876421 112234567777777776      368899999999999886422


Q NP_000290.2     674 QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       674 e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      .   ......+++.|..++.+. ++.++..++.+|..++...
T Consensus       413 ~---~~~~~~ll~~l~~~l~d~-~~~vR~~a~~~l~~i~~~~  450 (560)
T 3VWA_B          413 E---RQLNNELLRFLAKTQVDS-DVEIRTWTVIIISKISTIL  450 (560)
T ss_dssp             H---HCCCCCHHHHHHHHTTCS-SHHHHHHHHHHHHHHHTTS
T ss_pred             H---HHHHHHHHHHHHHHcCCC-CHHHHHHHHHHHHHHHHHh
Confidence            1   122335678888888776 7899999999999887643


No 493
>3C5W_A PP2A A subunit, PP2A C; methylesterase, phosphatase, PP2A, HYDROLASE; 2.8A {Homo sapiens}
Probab=68.82  E-value=0.38  Score=40.27  Aligned_cols=109  Identities=12%  Similarity=0.007  Sum_probs=69.9  Template_Neff=13.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      ..++.+...+.+.++.++..++..+..+.......   .....+++.+...+.+.++.++..++.++..+.......   
T Consensus         7 ~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~~~---~~~~~~~~~l~~~l~~~~~~vr~~~~~~l~~l~~~~~~~---   80 (232)
T 3C5W_A            7 YPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVE---RLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVE---   80 (232)
T ss_dssp             SHHHHHHHHHTCSSHHHHHHHHTTHHHHHHHHCSS---HCCCCCHHHHHHHTTCSSHHHHHHHHTTHHHHHHHHCGG---
T ss_pred             cHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHhChH---HHHHhHHHHHHHHHhCCCHHHHHHHHHHHHHHHHhhCHH---
Confidence            44556666777777888888888888876543211   112345666666677777788888888888776543211   


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      .....+++.+...+. +.++.++..++.++..+...
T Consensus        81 ~~~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~  115 (232)
T 3C5W_A           81 FFDEKLNSLCMAWLV-DHVYAIREAATSNLKKLVEK  115 (232)
T ss_dssp             GTTTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHh-CCCHHHHHHHHHHHHHHHHH
Confidence            112235555666665 45677888888888877754


No 494
>4K92_B CLIP-associating protein 1; HEAT-Repeat TOG domain, Regulator of; HET: MSE; 2.005A {Homo sapiens}
Probab=68.63  E-value=0.41  Score=43.13  Aligned_cols=109  Identities=12%  Similarity=0.075  Sum_probs=66.8  Template_Neff=11.700

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.++..+.+.+..++..++.++..+.....       ...+++.+...+.+.++.++..++.++..++........
T Consensus       129 ~~~l~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~-------~~~~~~~l~~~l~~~~~~~r~~~~~~l~~l~~~~~~~~~  201 (273)
T 4K92_B          129 EAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTH-------IPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSL  201 (273)
T ss_dssp             HHHHHHHHTTTTCSSHHHHHHHHHHHHHHHHHCC-------CTTHHHHHHGGGGCSCHHHHHHHHHHHHHHHHHSCHHHH
T ss_pred             HHHHHHHHHHCccccHHHHHHHHHHHHHHHHhCC-------CchHHHHHHHHcCCCCHHHHHHHHHHHHHHHHHcCchhH
Confidence            3445555555555566677777777777765321       123455555666666677888888888877754322100


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ......+++.+...+. +.+..++..++.++..+...
T Consensus       202 ~~~~~~i~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~  237 (273)
T 4K92_B          202 ERHISVLAETIKKGIH-DADSEARIEARKCYWGFHSH  237 (273)
T ss_dssp             TTCHHHHHHHHHHHHT-CSSHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHH
Confidence            1112345566666665 55778888888888888764


No 495
>6MQ7_B CLIP-associating protein 1; microtubule binding protein, STRUCTURAL PROTEIN; 1.78A {Homo sapiens}
Probab=68.63  E-value=0.41  Score=43.13  Aligned_cols=109  Identities=12%  Similarity=0.075  Sum_probs=66.8  Template_Neff=11.700

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.++..+.+.+..++..++.++..+.....       ...+++.+...+.+.++.++..++.++..++........
T Consensus       129 ~~~l~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~-------~~~~~~~l~~~l~~~~~~~r~~~~~~l~~l~~~~~~~~~  201 (273)
T 6MQ7_B          129 EAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTH-------IPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSL  201 (273)
T ss_dssp             HHHHHHHHTTTTCSSHHHHHHHHHHHHHHHHHCC-------CGGGHHHHHHGGGCSCHHHHHHHHHHHHHHHHHSCGGGT
T ss_pred             HHHHHHHHHHCccccHHHHHHHHHHHHHHHHhCC-------CchHHHHHHHHcCCCCHHHHHHHHHHHHHHHHHcCchhH
Confidence            3445555555555566677777777777765321       123455555666666677888888888877754322100


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ......+++.+...+. +.+..++..++.++..+...
T Consensus       202 ~~~~~~i~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~  237 (273)
T 6MQ7_B          202 ERHISVLAETIKKGIH-DADSEARIEARKCYWGFHSH  237 (273)
T ss_dssp             TTCHHHHHHHHHHHHT-CSSHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHH
Confidence            1112345566666665 55778888888888888764


No 496
>4LAC_A Serine/threonine-protein phosphatase 2A activator (E.C.5.2.1.8); PP2A, PTPA, protein phosphatase, signaling; HET: AGS, MES; 2.82A {Homo sapiens}
Probab=68.25  E-value=0.41  Score=41.40  Aligned_cols=109  Identities=7%  Similarity=-0.006  Sum_probs=68.9  Template_Neff=12.800

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+......   ......+++.+...+.+.+..++..++.++..+.......   
T Consensus       111 ~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~~---~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~---  184 (258)
T 4LAC_A          111 KLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGK---EWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQD---  184 (258)
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHHHcCCh---hHHHHhHHHHHHHHcCCCCHHHHHHHHHHHHHHHHcCCCC---
Confidence            3455556666666778888888888887654322   1112345566666666667778888888888776543221   


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      .....+++.+...+. +.++.++..++.++..+...
T Consensus       185 ~~~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~  219 (258)
T 4LAC_A          185 ITTKHMLPTVLRMAG-DPVANVRFNVAKSLQKIGPI  219 (258)
T ss_pred             ccHhhHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHH
Confidence            112345566666665 55677888888888887653


No 497
>6MQ5_A CLIP-associating protein 1; Microtubule Plus End Binding, STRUCTURAL; HET: MSE; 2.146A {Homo sapiens}
Probab=68.04  E-value=0.43  Score=42.33  Aligned_cols=108  Identities=10%  Similarity=0.048  Sum_probs=65.9  Template_Neff=11.900

Q NP_000290.2     245 LTIPKAV-QYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll-~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .++..+. .++.+.++.++..++.++..+........... ...+++.+...+.+.+..++..+..++..+......   
T Consensus        49 ~~~~~l~~~~l~d~~~~vr~~a~~~l~~l~~~~~~~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~---  124 (257)
T 6MQ5_A           49 KLVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQ-IGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQAAN---  124 (257)
T ss_dssp             HHHHHCCCCCTTCSSHHHHHHHHHHHHHHHHHHGGGGHHH-HHHHHHHHHHHTTCSCHHHHHHHHHHHHHHHHHTSC---
T ss_pred             HHHHHHHHHHhcCCcHHHHHHHHHHHHHHHHHhHHHHHHH-HHhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHccC---
Confidence            3444444 44556677788888888888876433221111 134566666666666677788888888777643211   


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                         ...+++.+...+. ..++.++..++.++..+...
T Consensus       125 ---~~~~~~~l~~~l~-~~~~~~r~~~l~~l~~l~~~  157 (257)
T 6MQ5_A          125 ---PQYVWDRMLGGFK-HKNFRTREGICLCLIATLNA  157 (257)
T ss_dssp             ---HHHHHHTTGGGGG-BSSHHHHHHHHHHHHHHHHH
T ss_pred             ---hHHHHHHHhhhcC-CCCHHHHHHHHHHHHHHHHH
Confidence               1234555555564 45677888888888877653


No 498
>2QK1_A Protein STU2; stu2, Stu2p, XMAP215, Dis1, TOG; 1.7A {Saccharomyces cerevisiae}
Probab=67.88  E-value=0.42  Score=40.93  Aligned_cols=116  Identities=3%  Similarity=-0.016  Sum_probs=68.4  Template_Neff=12.900

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTN--  321 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~--  321 (747)
                      ..+++.+...+.+.+..++..++.++..+...............+++.+...+.+.++.++..++.++..++......  
T Consensus       103 ~~~~~~l~~~l~~~~~~v~~~a~~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~vr~~~~~~l~~~~~~~~~~~~  182 (249)
T 2QK1_A          103 SLVFTPLLDRTKEKKPSVIEAIRKALLTICKYYDPLASSGRNEDMLKDILEHMKHKTPQIRMECTQLFNASMKEEKDGYS  182 (249)
T ss_dssp             HHHHHHHHHGGGCCCHHHHHHHHHHHHHHHHHSCTTCTTCTTHHHHHHHHHHTTCSSHHHHHHHHHHHHHHHHHCCSCSH
T ss_pred             HHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHhChhcccCCHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhccccch
Confidence            345556666666666777888888888776543210000111245566666666667778888888888776543310  


Q NP_000290.2     322 -KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       322 -~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                       ........+++.+...+. +.++.++..++.++..+...
T Consensus       183 ~~~~~~~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~  221 (249)
T 2QK1_A          183 TLQRYLKDEVVPIVIQIVN-DTQPAIRTIGFESFAILIKI  221 (249)
T ss_dssp             HHHHHCCCCCHHHHHHHHT-CSSHHHHHHHHHHHHHHHHH
T ss_pred             hhhHHHHHHHHHHHHHHHc-CCCHHHHHHHHHHHHHHHHH
Confidence             000111235555666665 55677888888888877653


No 499
>4D4Z_A DEOXYHYPUSINE HYDROXYLASE (E.C.1.14.99.29); OXIDOREDUCTASE, EIF-5A, HYPUSINE; HET: B3P, GOL; 1.7A {HOMO SAPIENS}
Probab=67.63  E-value=0.43  Score=42.31  Aligned_cols=60  Identities=10%  Similarity=0.123  Sum_probs=34.5  Template_Neff=12.700

Q NP_000290.2     547 DAIRTYLNLMGKSK--KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       547 G~I~~LL~LL~ss~--d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      ..++.|...+. +.  ++.++..++.+|..+...                ..++.+...+.+.++.++..++.+|..+.
T Consensus        74 ~~~~~l~~~l~-~~~~~~~vr~~a~~~l~~~~~~----------------~~~~~l~~~l~~~~~~v~~~a~~~l~~~~  135 (294)
T 4D4Z_A           74 RAIPMLVDVLQ-DTRQEPMVRHEAGEALGAIGDP----------------EVLEILKQYSSDPVIEVAETCQLAVRRLE  135 (294)
T ss_dssp             GGHHHHHHHHH-CTTSCHHHHHHHHHHHHHHCCG----------------GGHHHHHHHTTCSSHHHHHHHHHHHHHHH
T ss_pred             chHHHHHHHhh-CCCCCHHHHHHHHHHHHHhCCH----------------HHHHHHHHHccCCCchHHHHHHHHHHHHH
Confidence            34556666666 34  566777777776655421                12334455555556666666666666553


No 500
>4D50_A DEOXYHYPUSINE HYDROXYLASE (E.C.1.14.99.29); OXIDOREDUCTASE; HET: GAI; 1.7A {HOMO SAPIENS}
Probab=67.63  E-value=0.43  Score=42.31  Aligned_cols=60  Identities=10%  Similarity=0.123  Sum_probs=34.5  Template_Neff=12.700

Q NP_000290.2     547 DAIRTYLNLMGKSK--KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       547 G~I~~LL~LL~ss~--d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      ..++.|...+. +.  ++.++..++.+|..+...                ..++.+...+.+.++.++..++.+|..+.
T Consensus        74 ~~~~~l~~~l~-~~~~~~~vr~~a~~~l~~~~~~----------------~~~~~l~~~l~~~~~~v~~~a~~~l~~~~  135 (294)
T 4D50_A           74 RAIPMLVDVLQ-DTRQEPMVRHEAGEALGAIGDP----------------EVLEILKQYSSDPVIEVAETCQLAVRRLE  135 (294)
T ss_dssp             GGHHHHHHHHH-CTTSCHHHHHHHHHHHHHHCCG----------------GGHHHHHHHTTCSSHHHHHHHHHHHHHHH
T ss_pred             chHHHHHHHhh-CCCCCHHHHHHHHHHHHHhCCH----------------HHHHHHHHHccCCCchHHHHHHHHHHHHH
Confidence            34556666666 34  566777777776655421                12334455555556666666666666553