Mercurial > repos > iuc > hamronize_summarize
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planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hamronization commit b49fc153425676a82e77dec090676403112bcbe6
| author | iuc |
|---|---|
| date | Tue, 05 Mar 2024 19:47:21 +0000 |
| parents | ef76d74a7171 |
| children |
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#ariba_ref_name ref_name gene var_only flag reads cluster ref_len ref_base_assembled pc_ident ctg ctg_len ctg_cov known_var var_type var_seq_type known_var_change has_known_var ref_ctg_change ref_ctg_effect ref_start ref_end ref_nt ctg_start ctg_end ctg_nt smtls_total_depth smtls_nts smtls_nts_depth var_description free_text AAC_3__IId.3004623.EU022314.1.0_861.5344 AAC_3__IId.3004623.EU022314.1.0_861.5344 1 0 27 256 AAC_3__II- 861 861 99.88 AAC_3__II-.l15.c4.ctg.1 1547 37.8 . . . . . . . . . . . . . . . . . b'AAC(3)-IId is a plasmid-encoded aminoglycoside acetyltransferase in E. coli';AAC(3)-IId AAC_6___Ib4.3002577.AF445082.2788_3343.401 AAC_6___Ib4.3002577.AF445082.2788_3343.401 1 0 667 510 AAC_6___Ib+ 555 555 99.64 AAC_6___Ib+.l15.c30.ctg.1 619 128.1 0 . p . 0 W87R NONSYN 259 261 TGG 264 266 CGG 86;89;90 C,T,A;G;G 30,28,1;59;63 . AAC(6')-Ib4;b"AAC(6')-Ib4 is an aminoglycoside acetyltransferase in Serratia spp." AAC_6___Ib4.3002577.AF445082.2788_3343.401 AAC_6___Ib4.3002577.AF445082.2788_3343.401 1 0 667 510 AAC_6___Ib+ 555 555 99.64 AAC_6___Ib+.l15.c30.ctg.1 619 128.1 0 . p . 0 S102L NONSYN 304 306 TCA 309 311 TTA 92;92;92 T;T;A 70;70;71 . AAC(6')-Ib4;b"AAC(6')-Ib4 is an aminoglycoside acetyltransferase in Serratia spp." AAC_6___Ib4.3002577.AF445082.2788_3343.401 AAC_6___Ib4.3002577.AF445082.2788_3343.401 1 0 667 510 AAC_6___Ib+ 555 555 99.64 AAC_6___Ib+.l15.c30.ctg.1 619 128.1 0 HET . . . G490T . 490 490 G 495 495 G 139 G,T 57,46 . AAC(6')-Ib4;b"AAC(6')-Ib4 is an aminoglycoside acetyltransferase in Serratia spp." BRP_MBL_.3001205.KC503911.1.9883_10249.5446 BRP_MBL_.3001205.KC503911.1.9883_10249.5446 1 0 27 132 BRP_MBL_ 366 366 100.0 BRP_MBL_.l6.c4.ctg.1 1085 27.3 . . . . . . . . . . . . . . . . . BRP(MBL);b'A novel bleomycin resistance protein encoded by a metallo-beta-lactamase-associated ble gene. Expression of BRP(MBL) confers resistance to bleomycin and bleomycin-like antibiotics in Enterobacteriaceae and Acinetobacter, where it is co-expressed with an MBL and controlled by the same promoter region.' CRP.3000518.AP009048.1.4153663_4154296.4752 CRP.3000518.AP009048.1.4153663_4154296.4752 1 0 528 58 CRP 633 146 93.84 CRP.l15.c4.ctg.1 477 24.1 0 . p . 0 K29T NONSYN 85 87 AAG 414 416 ACG 14;14;13 A;C;G 10;10;10 . b'CRP is a global regulator that represses MdtEF multidrug efflux pump expression.';CRP CTX_M_15.3001878.AY044436.1435_2311.1430 CTX_M_15.3001878.AY044436.1435_2311.1430 1 0 27 274 CTX_M_- 876 876 100.0 CTX_M_-.l15.c4.ctg.1 1793 36.0 . . . . . . . . . . . . . . . . . CTX-M-15;b'CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family' DHA_7.3002136.HQ456945.0_1140.1865 DHA_7.3002136.HQ456945.0_1140.1865 1 0 16 170 DHA_- 1140 796 100.0 DHA_-.l15.c4.ctg.1 1350 29.8 . . . . . . . . . . . . . . . . . b'DHA-7 is a beta-lactamase found in the Enterobacteriaceae family';DHA-7 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 T72A SNP 72 72 T 86 86 A 506 A 125 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 T113G SNP 113 113 T 127 127 G 376 G 146 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 T135C SNP 135 135 T 149 149 C 343 C,T 116,40 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 T137A SNP 137 137 T 151 151 A 321 A,C 157,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A144G SNP 144 144 A 158 158 G 311 G,A 120,41 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A152G SNP 152 152 A 166 166 G 344 G 196 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C163A SNP 163 163 C 177 177 A 353 A 216 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 T174C SNP 174 174 T 188 188 C 364 C 229 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 G264C SNP 264 264 G 278 278 C 415 C,T,G 306,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C274T SNP 274 274 C 288 288 T 398 T,C 305,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 G285T SNP 285 285 G 299 299 T 394 T,C,A 299,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C302G SNP 302 302 C 316 316 G 406 G 303 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 G315. DEL 315 315 G 328 328 C 409 C,A,T 302,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 .317A INS 317 317 G 331 331 A 409 A,T 300,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A320G SNP 320 320 A 334 334 G 422 G,A 316,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C331T SNP 331 331 C 345 345 T 441 T,C 328,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C334T SNP 334 334 C 348 348 T 445 T,A,G,C 326,1,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A344C SNP 344 344 A 358 358 C 441 C,A 329,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C357T SNP 357 357 C 371 371 T 446 T,C,G,A 260,76,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 G363A SNP 363 363 G 377 377 A 452 A,C 339,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 T369A SNP 369 369 T 383 383 A 479 A,C 347,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 G543C SNP 543 543 G 556 556 C 574 C,A 407,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A547C SNP 547 547 A 560 560 C 572 C 407 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C550. DEL 550 550 C 562 562 G 577 G,A,T 412,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A613T SNP 613 613 A 625 625 T 657 T,C,A 504,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A626C SNP 626 626 A 638 638 C 634 C,T 474,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C853T SNP 853 853 C 865 865 T 658 T,G 473,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A877T SNP 877 877 A 889 889 T 668 T,C,G 501,2,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 G914A SNP 914 914 G 926 926 A 673 A 477 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 G924A SNP 924 924 G 936 936 A 624 A,G 450,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C1044A SNP 1044 1044 C 1056 1056 A 534 A,G 414,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 T1173. DEL 1173 1173 T 1184 1184 C 563 C,G 421,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C1178T SNP 1178 1178 C 1189 1189 T 575 T,C,A 438,2,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 T1211C SNP 1211 1211 T 1222 1222 C 583 C,G,A 441,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A1220G SNP 1220 1220 A 1231 1231 G 593 G,C,A,T 413,40,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 T1229C SNP 1229 1229 T 1240 1240 C 599 C,G,A 417,39,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 G1444A SNP 1444 1444 G 1455 1455 A 639 A,G,T 491,2,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 G1473A SNP 1473 1473 G 1484 1484 A 659 A,G,T 502,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 T1486A SNP 1486 1486 T 1497 1497 A 633 A,G,T 328,160,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A1503T SNP 1503 1503 A 1514 1514 T 634 T,A 487,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C1518T SNP 1518 1518 C 1529 1529 T 623 T,C,G 483,1,2 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C1547T SNP 1547 1547 C 1558 1558 T 689 T,C 502,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A1713G SNP 1713 1713 A 1724 1724 G 675 G,A,C 499,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C1725. DEL 1725 1725 C 1735 1735 G 643 G,T 483,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A1727C SNP 1727 1727 A 1737 1737 C 640 C,A,G 475,1,2 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 T1729C SNP 1729 1729 T 1739 1739 C 638 C,T 477,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C1734G SNP 1734 1734 C 1744 1744 G 644 G,T,A 482,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 G1735A SNP 1735 1735 G 1745 1745 A 645 A,T 487,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A1745G SNP 1745 1745 A 1755 1755 G 659 G,A,T 497,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 T1747C SNP 1747 1747 T 1757 1757 C 650 C,T 490,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 .1866T INS 1866 1866 A 1877 1877 T 636 T 475 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 G1867C SNP 1867 1867 G 1878 1878 C 637 C,A,T 473,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 .1872G INS 1872 1872 A 1884 1884 G 651 G,A,C 476,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C1874A SNP 1874 1874 C 1886 1886 A 652 A 476 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 T2137C SNP 2137 2137 T 2149 2149 C 554 C,G 426,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A2154G SNP 2154 2154 A 2166 2166 G 581 G,T,A 435,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 G2162A SNP 2162 2162 G 2174 2174 A 590 A,G 443,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A2205G SNP 2205 2205 A 2217 2217 G 596 G 454 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A2211G SNP 2211 2211 A 2223 2223 G 605 G,C,A 456,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 T2213C SNP 2213 2213 T 2225 2225 C 625 C 462 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C2215G SNP 2215 2215 C 2227 2227 G 622 G,T 462,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 T2265C SNP 2265 2265 T 2277 2277 C 677 C,T,A 504,3,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 A2270C SNP 2270 2270 A 2282 2282 C 685 C,G 510,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 G2293A SNP 2293 2293 G 2305 2305 A 711 A,G 533,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C2339T SNP 2339 2339 C 2351 2351 T 733 T,C,G 520,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 . n . 0 C2636T SNP 2636 2636 C 2648 2648 T 644 T,G,C 463,1,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 1 SNP n G2032U 0 . . 2032 2032 G 2044 2044 G 671 G 470 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164:0:0:G2032U:.:b'Point mutation in the 23S rRNA of Escherichia coli shown to confer resistance to oxazolidinone type antibiotics' Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 1 SNP n G2032A 0 . . 2032 2032 G 2044 2044 G 671 G 470 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164:0:0:G2032A:.:b'Point mutation in the 23S rRNA of Escherichia coli shown to confer resistance to oxazolidinone type antibiotics' Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 1 SNP n G2032C 0 . . 2032 2032 G 2044 2044 G 671 G 470 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164:0:0:G2032C:.:b'Point mutation in the 23S rRNA of Escherichia coli shown to confer resistance to oxazolidinone type antibiotics' Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 1 SNP n G2447U 0 . . 2447 2447 G 2459 2459 G 681 G 498 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164:0:0:G2447U:.:b'Point mutation in the 23S rRNA of Escherichia coli shown to confer resistance to oxazolidinone type antibiotics' Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 HET . . . C1595T,A . 1595 1595 C 1606 1606 C 742 C,T,A 425,112,1 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 HET . . . T1506C . 1506 1506 T 1517 1517 T 634 T,C 427,58 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 HET . . . T102C . 102 102 T 116 116 T 433 T,C 116,28 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 HET . . . A104G . 104 104 A 118 118 A 433 A,G 117,28 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 HET . . . A136G . 136 136 G 150 150 A 322 A,G 118,40 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 HET . . . G1483A . 1483 1483 G 1494 1494 G 635 G,A 325,161 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 Escherichia_coli_23S.3004173.AE014075.1.237159_240063.4164 0 0 659 8302 Escherichia_coli_23S 2904 2792 97.1 Escherichia_coli_23S.l15.c17.ctg.1 2822 611.4 0 HET . . . T143C . 143 143 C 157 157 T 311 T,C 122,40 . Escherichia coli 23S rRNA with mutation conferring resistance to oxazolidinone antibiotics Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 1 1 667 624 Escherichia_coli_EF_Tu 1185 1185 96.12 Escherichia_coli_EF_Tu.l15.c30.ctg.1 1369 106.2 0 . p . 0 A43S NONSYN 127 129 GCT 293 295 TCT 128;129;129 T;C;T,C 91;91;71,20 . Escherichia coli EF-Tu mutants conferring resistance to Enacyloxin IIa Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 1 1 667 624 Escherichia_coli_EF_Tu 1185 1185 96.12 Escherichia_coli_EF_Tu.l15.c30.ctg.1 1369 106.2 0 . p . 0 L190I NONSYN 568 570 CTG 734 736 ATC 134;135;135 A,G;T;C 101,1;101;102 . Escherichia coli EF-Tu mutants conferring resistance to Enacyloxin IIa Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 1 1 667 624 Escherichia_coli_EF_Tu 1185 1185 96.12 Escherichia_coli_EF_Tu.l15.c30.ctg.1 1369 106.2 0 . p . 0 F195H NONSYN 583 585 TTC 749 751 CAC 137;137;140 C;A;C 102;101;105 . Escherichia coli EF-Tu mutants conferring resistance to Enacyloxin IIa Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 1 1 667 624 Escherichia_coli_EF_Tu 1185 1185 96.12 Escherichia_coli_EF_Tu.l15.c30.ctg.1 1369 106.2 0 . p . 0 S198T NONSYN 592 594 TCT 758 760 ACC 145;148;145 A;C;C 108;110;107 . Escherichia coli EF-Tu mutants conferring resistance to Enacyloxin IIa Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 1 1 667 624 Escherichia_coli_EF_Tu 1185 1185 96.12 Escherichia_coli_EF_Tu.l15.c30.ctg.1 1369 106.2 0 . p . 0 Q252A NONSYN 754 756 CAG 920 922 GCG 104;103;103 G;C;G 83;82;82 . Escherichia coli EF-Tu mutants conferring resistance to Enacyloxin IIa Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 1 1 667 624 Escherichia_coli_EF_Tu 1185 1185 96.12 Escherichia_coli_EF_Tu.l15.c30.ctg.1 1369 106.2 0 . p . 0 S254T NONSYN 760 762 TCT 926 928 ACC 102;102;109 A,T;C;C,T 81,1;82;81,1 . Escherichia coli EF-Tu mutants conferring resistance to Enacyloxin IIa Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 1 1 667 624 Escherichia_coli_EF_Tu 1185 1185 96.12 Escherichia_coli_EF_Tu.l15.c30.ctg.1 1369 106.2 0 . p . 0 K300N NONSYN 898 900 AAG 1064 1066 AAC 141;140;144 A;A,T,G;C,G 102;99,1,1;101,1 . Escherichia coli EF-Tu mutants conferring resistance to Enacyloxin IIa Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 1 1 667 624 Escherichia_coli_EF_Tu 1185 1185 96.12 Escherichia_coli_EF_Tu.l15.c30.ctg.1 1369 106.2 0 HET . . . T960C . 960 960 T 1126 1126 T 120 T,C 44,50 . Escherichia coli EF-Tu mutants conferring resistance to Enacyloxin IIa Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 Escherichia_coli_EF_Tu.3003370.U00096.3.3470144_3471329.5280 1 1 667 624 Escherichia_coli_EF_Tu 1185 1185 96.12 Escherichia_coli_EF_Tu.l15.c30.ctg.1 1369 106.2 0 HET . . . T78A . 78 78 T 244 244 T 110 T,A 67,9 . Escherichia coli EF-Tu mutants conferring resistance to Enacyloxin IIa Escherichia_coli_PtsI.3003899.HG738867.2416338_2418066.3675 Escherichia_coli_PtsI.3003899.HG738867.2416338_2418066.3675 1 1 528 182 Escherichia_coli_PtsI 1728 921 91.64 Escherichia_coli_PtsI.l15.c4.ctg.2 1312 23.5 0 . p . 0 I360V NONSYN 1078 1080 ATC 274 276 GTG 10;10;10 G;T;G 7;7;7 . Escherichia coli PtsI with mutation conferring resistance to fosfomycin Escherichia_coli_PtsI.3003899.HG738867.2416338_2418066.3675 Escherichia_coli_PtsI.3003899.HG738867.2416338_2418066.3675 1 1 528 182 Escherichia_coli_PtsI 1728 921 91.64 Escherichia_coli_PtsI.l15.c4.ctg.2 1312 23.5 0 . p . 0 R367K NONSYN 1099 1101 AGA 295 297 AAA 13;13;13 A;A;A 9;9;9 . Escherichia coli PtsI with mutation conferring resistance to fosfomycin Escherichia_coli_PtsI.3003899.HG738867.2416338_2418066.3675 Escherichia_coli_PtsI.3003899.HG738867.2416338_2418066.3675 1 1 528 182 Escherichia_coli_PtsI 1728 921 91.64 Escherichia_coli_PtsI.l15.c4.ctg.2 1312 23.5 0 . p . 0 L374V NONSYN 1120 1122 CTC 316 318 GTT 13;13;13 G;T;T 8;8;9 . Escherichia coli PtsI with mutation conferring resistance to fosfomycin Escherichia_coli_PtsI.3003899.HG738867.2416338_2418066.3675 Escherichia_coli_PtsI.3003899.HG738867.2416338_2418066.3675 1 1 528 182 Escherichia_coli_PtsI 1728 921 91.64 Escherichia_coli_PtsI.l15.c4.ctg.2 1312 23.5 0 . p . 0 R403K NONSYN 1207 1209 CGC 403 405 AAG 17;17;17 A;A;G 10;10;10 . Escherichia coli PtsI with mutation conferring resistance to fosfomycin FosA6.3004111.KU254579.1.59421_59841.4755 FosA6.3004111.KU254579.1.59421_59841.4755 1 0 539 196 FosA-_1 420 420 98.81 FosA-_1.l15.c4.ctg.1 1646 27.2 0 . p . 0 I91V NONSYN 271 273 ATC 808 810 GTC 47;48;49 G;T;C 36;38;39 . b'fosA6 is a plasmid-encoded enzyme that confers resistance to fosfomycin in Escherichia coli by breaking the epoxide ring of the molecule.';FosA6 FosA6.3004111.KU254579.1.59421_59841.4755 FosA6.3004111.KU254579.1.59421_59841.4755 1 0 539 196 FosA-_1 420 420 98.81 FosA-_1.l15.c4.ctg.1 1646 27.2 0 . p . 0 Q130P NONSYN 388 390 CAG 925 927 CCG 79;79;80 C;C;G 60;60;61 . b'fosA6 is a plasmid-encoded enzyme that confers resistance to fosfomycin in Escherichia coli by breaking the epoxide ring of the molecule.';FosA6 FosA6.3004111.KU254579.1.59421_59841.4755 FosA6.3004111.KU254579.1.59421_59841.4755 1 0 539 196 FosA-_1 420 420 98.81 FosA-_1.l15.c4.ctg.1 1646 27.2 0 . p . 0 D138E NONSYN 412 414 GAT 949 951 GAA 74;74;74 G;A;A 56;56;57 . b'fosA6 is a plasmid-encoded enzyme that confers resistance to fosfomycin in Escherichia coli by breaking the epoxide ring of the molecule.';FosA6 H_NS.3000676.BA000007.3.1737690_1738104.5476 H_NS.3000676.BA000007.3.1737690_1738104.5476 1 0 16 44 H_NS 414 111 93.69 H_NS.l15.c4.ctg.1 379 20.6 . . . . . . . . . . . . . . . . . H-NS;b'H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE, mdtE, and emrK as well as nearby genes of many RND-type multidrug exporters.' Klebsiella_mutant_PhoP.3003585.FO834906.1.2325636_2326308.4715 Klebsiella_mutant_PhoP.3003585.FO834906.1.2325636_2326308.4715 1 1 27 328 Klebsiella_mutant_PhoP 672 672 100.0 Klebsiella_mutant_PhoP.l6.c4.ctg.1 1493 48.2 1 SNP p D191Y 0 . . 571 573 GAC 889 891 GAC 104;104;102 G;A;C 77;77;76 Klebsiella_mutant_PhoP.3003585.FO834906.1.2325636_2326308.4715:1:1:D191Y:.:b'A mutant phoP activates pmrHFIJKLM expression responsible for L-aminoarabinose synthesis and polymyxin resistance, by way of alteration of negative charge' Klebsiella mutant PhoP conferring antibiotic resistance to colistin Klebsiella_pneumoniae_KpnE.3004580.AP006725.1.2483889_2484252.5313 Klebsiella_pneumoniae_KpnE.3004580.AP006725.1.2483889_2484252.5313 1 0 539 320 Klebsiella_pneumoniae_KpnE 363 363 99.45 Klebsiella_pneumoniae_KpnE.l15.c4.ctg.1 1236 56.7 0 . p . 0 Q112K NONSYN 334 336 CAG 736 738 AAG 119;119;119 A;A;G 95;95;95 . b'KpnE subunit of KpnEF resembles EbrAB from E. coli. Mutation in KpnEF resulted in increased susceptibility to cefepime, ceftriaxon, colistin, erythromycin, rifampin, tetracycline, and streptomycin as well as enhanced sensitivity toward sodium dodecyl sulfate, deoxycholate, dyes, benzalkonium chloride, chlorhexidine, and triclosan';Klebsiella pneumoniae KpnE Klebsiella_pneumoniae_KpnF.3004583.AP006725.1.2484238_2484568.5312 Klebsiella_pneumoniae_KpnF.3004583.AP006725.1.2484238_2484568.5312 1 0 27 280 Klebsiella_pneumoniae_KpnF 330 330 100.0 Klebsiella_pneumoniae_KpnF.l15.c4.ctg.1 1352 45.9 . . . . . . . . . . . . . . . . . b'KpnF subunit of KpnEF resembles EbrAB from E. coli. Mutation in KpnEF resulted in increased susceptibility to cefepime, ceftriaxon, colistin, erythromycin, rifampin, tetracycline, and streptomycin as well as enhanced sensitivity toward sodium dodecyl sulfate, deoxycholate, dyes, benzalkonium chloride, chlorhexidine, and triclosan.';Klebsiella pneumoniae KpnF Klebsiella_pneumoniae_KpnG.3004588.ACWO01000051.1.22092_23265.5311 Klebsiella_pneumoniae_KpnG.3004588.ACWO01000051.1.22092_23265.5311 1 0 539 510 Klebsiella_pneumoniae_KpnG 1173 1173 99.32 Klebsiella_pneumoniae_KpnG.l15.c4.ctg.1 1780 66.3 0 . p . 0 S137A NONSYN 409 411 TCC 813 815 GCC 77;77;77 G;C;C 61;61;61 . Klebsiella pneumoniae KpnG;b'KpnG consists of ~390 residues and resembles EmrA of E. coli. Disruption of the pump components KpnG-KpnH signficantly decrease resistance to azithromycin, ceftazidime, ciprofloxacin, ertapenem, erythromycin, gentamicin, imipenem, ticarcillin, norfloxacin, polymyxin-B, piperacillin, spectinomycin, tobramycin, and streptomycin' Klebsiella_pneumoniae_OmpK35.3003966.NC_016845.1.1904307_1904991.5852 Klebsiella_pneumoniae_OmpK35.3003966.NC_016845.1.1904307_1904991.5852 1 0 27 404 Klebsiella_pneumoniae_OmpK35 684 684 100.0 Klebsiella_pneumoniae_OmpK35.l15.c4.ctg.1 1394 66.2 . . . . . . . . . . . . . . . . . b'Klebsiella pneumoniae outer membrane porin protein. In beta-lactam-resistant Klebsiella, this porin is often deleted, limiting diffusion of the antibiotic into the cell. Klebsiella strains expressing OmpK35 are often beta-lactam sensitive even in the presence of beta-lactamases because of an inefficient mechanism.';Klebsiella pneumoniae OmpK35 Klebsiella_pneumoniae_OmpK36.3003968.NC_016845.1.3727881_3728985.5853 Klebsiella_pneumoniae_OmpK36.3003968.NC_016845.1.3727881_3728985.5853 1 0 539 584 Klebsiella_pneumoniae_OmpK36 1104 1104 99.82 Klebsiella_pneumoniae_OmpK36.l15.c4.ctg.1 1845 74.2 0 . p . 0 K195E NONSYN 583 585 AAA 1061 1063 GAA 88;88;88 G;A;A 62;63;62 . Klebsiella pneumoniae OmpK36;b'Klebsiella pneumoniae outer membrane porin protein. In beta-lactam-resistant Klebsiella, this porin is often deleted, limiting diffusion of the antibiotic into the cell. Klebsiella strains expressing OmpK36 are often beta-lactam sensitive even in the presence of beta-lactamases because of an inefficient mechanism.' Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 1 0 539 526 Klebsiella_pneumoniae_OmpK37 1125 1125 95.5 Klebsiella_pneumoniae_OmpK37.l6.c4.ctg.1 1846 66.2 0 . p . 0 I70M NONSYN 208 210 ATT 459 461 ATG 88;88;88 A;T;G 58;58;58 . b'Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36, which did not allow penetration by certain beta-lactams. Also, when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35.';Klebsiella pneumoniae OmpK37 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 1 0 539 526 Klebsiella_pneumoniae_OmpK37 1125 1125 95.5 Klebsiella_pneumoniae_OmpK37.l6.c4.ctg.1 1846 66.2 0 . p . 0 I128M NONSYN 382 384 ATT 633 635 ATG 58;58;57 A;T;G,T 51;51;49,1 . b'Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36, which did not allow penetration by certain beta-lactams. Also, when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35.';Klebsiella pneumoniae OmpK37 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 1 0 539 526 Klebsiella_pneumoniae_OmpK37 1125 1125 95.5 Klebsiella_pneumoniae_OmpK37.l6.c4.ctg.1 1846 66.2 0 . p . 0 N230G NONSYN 688 690 AAC 939 941 GGC 46;46;46 G;G;C 39;39;38 . b'Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36, which did not allow penetration by certain beta-lactams. Also, when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35.';Klebsiella pneumoniae OmpK37 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 1 0 539 526 Klebsiella_pneumoniae_OmpK37 1125 1125 95.5 Klebsiella_pneumoniae_OmpK37.l6.c4.ctg.1 1846 66.2 0 . p . 0 Q232fs FSHIFT 694 694 C 945 945 C 46 C 39 . b'Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36, which did not allow penetration by certain beta-lactams. Also, when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35.';Klebsiella pneumoniae OmpK37 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 1 0 539 526 Klebsiella_pneumoniae_OmpK37 1125 1125 95.5 Klebsiella_pneumoniae_OmpK37.l6.c4.ctg.1 1846 66.2 0 . p . 0 . MULTIPLE 697 699 ATG 953 956 CTAT 49;47;50;51 C;T;A;T 42;40;43;44 . b'Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36, which did not allow penetration by certain beta-lactams. Also, when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35.';Klebsiella pneumoniae OmpK37 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 1 0 539 526 Klebsiella_pneumoniae_OmpK37 1125 1125 95.5 Klebsiella_pneumoniae_OmpK37.l6.c4.ctg.1 1846 66.2 0 . p . 0 Q235H NONSYN 703 705 CAG 960 962 CAC 47;45;45 C;A;C 39;38;38 . b'Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36, which did not allow penetration by certain beta-lactams. Also, when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35.';Klebsiella pneumoniae OmpK37 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 1 0 539 526 Klebsiella_pneumoniae_OmpK37 1125 1125 95.5 Klebsiella_pneumoniae_OmpK37.l6.c4.ctg.1 1846 66.2 0 . p . 0 T236fs FSHIFT 706 706 A 963 963 A 45 A 37 . b'Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36, which did not allow penetration by certain beta-lactams. Also, when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35.';Klebsiella pneumoniae OmpK37 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 1 0 539 526 Klebsiella_pneumoniae_OmpK37 1125 1125 95.5 Klebsiella_pneumoniae_OmpK37.l6.c4.ctg.1 1846 66.2 0 . p . 0 A238_R239insI INS 712 712 G 971 971 A 48 A 38 . b'Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36, which did not allow penetration by certain beta-lactams. Also, when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35.';Klebsiella pneumoniae OmpK37 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 1 0 539 526 Klebsiella_pneumoniae_OmpK37 1125 1125 95.5 Klebsiella_pneumoniae_OmpK37.l6.c4.ctg.1 1846 66.2 0 . p . 0 . MULTIPLE 715 717 CGC 977 980 CAAA 48;48;48;48 C;A;A;A 38;37;37;37 . b'Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36, which did not allow penetration by certain beta-lactams. Also, when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35.';Klebsiella pneumoniae OmpK37 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 1 0 539 526 Klebsiella_pneumoniae_OmpK37 1125 1125 95.5 Klebsiella_pneumoniae_OmpK37.l6.c4.ctg.1 1846 66.2 0 . p . 0 E244D NONSYN 730 732 GAA 993 995 GAC 55;55;54 G;A;C,A 38;39;36,4 . b'Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36, which did not allow penetration by certain beta-lactams. Also, when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35.';Klebsiella pneumoniae OmpK37 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 1 0 539 526 Klebsiella_pneumoniae_OmpK37 1125 1125 95.5 Klebsiella_pneumoniae_OmpK37.l6.c4.ctg.1 1846 66.2 0 . p . 0 G273_N274insLY INS 817 817 G 1080 1080 G 50 G 40 . b'Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36, which did not allow penetration by certain beta-lactams. Also, when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35.';Klebsiella pneumoniae OmpK37 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 1 0 539 526 Klebsiella_pneumoniae_OmpK37 1125 1125 95.5 Klebsiella_pneumoniae_OmpK37.l6.c4.ctg.1 1846 66.2 0 . p . 0 . INDELS 820 822 AAT 1090 1095 GCAGTA 52;52;53;56;56;56 G,A;C;A;G;T;A 42,1;43;42;46;46;46 . b'Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36, which did not allow penetration by certain beta-lactams. Also, when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35.';Klebsiella pneumoniae OmpK37 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 1 0 539 526 Klebsiella_pneumoniae_OmpK37 1125 1125 95.5 Klebsiella_pneumoniae_OmpK37.l6.c4.ctg.1 1846 66.2 0 . p . 0 . MULTIPLE 823 825 GAC 1098 1101 AACG 56;56;57;57 A;A;C;G 46;46;47;45 . b'Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36, which did not allow penetration by certain beta-lactams. Also, when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35.';Klebsiella pneumoniae OmpK37 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 Klebsiella_pneumoniae_OmpK37.3004122.AJ011502.1.300_1425.4406 1 0 539 526 Klebsiella_pneumoniae_OmpK37 1125 1125 95.5 Klebsiella_pneumoniae_OmpK37.l6.c4.ctg.1 1846 66.2 0 . p . 0 . MULTIPLE 829 831 GTG 1108 1112 GTATC 58;58;58;58;59 G;T;A;T;C 48;48;48;47;49 . b'Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36, which did not allow penetration by certain beta-lactams. Also, when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35.';Klebsiella pneumoniae OmpK37 NDM_1.3000589.FN396876.2406_3219.4450 NDM_1.3000589.FN396876.2406_3219.4450 1 0 27 186 NDM_- 813 813 100.0 NDM_-.l15.c4.ctg.1 1601 27.2 . . . . . . . . . . . . . . . . . NDM-1;b'NDM-1 is a metallo-beta-lactamase isolated from Klebsiella pneumoniae with nearly complete resistance to all beta-lactam antibiotics.' OXA_1.3001396.JN420336.1.1399_2230.4668 OXA_1.3001396.JN420336.1.1399_2230.4668 1 0 27 188 OXA_-_3 831 831 100.0 OXA_-_3.l15.c4.ctg.1 1942 22.5 . . . . . . . . . . . . . . . . . b'OXA-1 is a beta-lactamase found in E. coli';OXA-1 SHV_182.3001364.KP050489.0_861.2124 SHV_182.3001364.KP050489.0_861.2124 1 0 539 376 SHV_- 861 861 99.88 SHV_-.l15.c4.ctg.1 2154 41.0 0 . p . 0 T102S NONSYN 304 306 ACG 805 807 TCG 52;52;52 T;C;G 43;43;43 . SHV-182;b'From the Lahey list of beta-lactamases.' acrA.3004041.AJ318073.1.793_1990.3994 acrA.3004041.AJ318073.1.793_1990.3994 1 0 539 534 acrA 1197 1197 97.74 acrA.l15.c4.ctg.1 2009 61.7 0 . p . 0 F92S NONSYN 274 276 TTC 820 822 TCC 77;77;77 T;C;C 63;63;62 . b'AcrA is a subunit of the AcrAB multidrug efflux system that in K. pneumoniae, which is encoded by the acrRAB operon.';Klebsiella pneumoniae acrA acrA.3004041.AJ318073.1.793_1990.3994 acrA.3004041.AJ318073.1.793_1990.3994 1 0 539 534 acrA 1197 1197 97.74 acrA.l15.c4.ctg.1 2009 61.7 0 . p . 0 G103A NONSYN 307 309 GGC 853 855 GCC 66;66;66 G;C;C 54;54;54 . b'AcrA is a subunit of the AcrAB multidrug efflux system that in K. pneumoniae, which is encoded by the acrRAB operon.';Klebsiella pneumoniae acrA acrA.3004041.AJ318073.1.793_1990.3994 acrA.3004041.AJ318073.1.793_1990.3994 1 0 539 534 acrA 1197 1197 97.74 acrA.l15.c4.ctg.1 2009 61.7 0 . p . 0 Q136K NONSYN 406 408 CAA 952 954 AAA 55;55;57 A;A;A 42;42;44 . b'AcrA is a subunit of the AcrAB multidrug efflux system that in K. pneumoniae, which is encoded by the acrRAB operon.';Klebsiella pneumoniae acrA acrA.3004041.AJ318073.1.793_1990.3994 acrA.3004041.AJ318073.1.793_1990.3994 1 0 539 534 acrA 1197 1197 97.74 acrA.l15.c4.ctg.1 2009 61.7 0 . p . 0 P145T NONSYN 433 435 CCC 979 981 ACC 54;54;53 A;C;C 39;38;35 . b'AcrA is a subunit of the AcrAB multidrug efflux system that in K. pneumoniae, which is encoded by the acrRAB operon.';Klebsiella pneumoniae acrA acrA.3004041.AJ318073.1.793_1990.3994 acrA.3004041.AJ318073.1.793_1990.3994 1 0 539 534 acrA 1197 1197 97.74 acrA.l15.c4.ctg.1 2009 61.7 0 . p . 0 N153S NONSYN 457 459 AAC 1003 1005 AGC 49;49;49 A;G;C 39;39;39 . b'AcrA is a subunit of the AcrAB multidrug efflux system that in K. pneumoniae, which is encoded by the acrRAB operon.';Klebsiella pneumoniae acrA acrA.3004041.AJ318073.1.793_1990.3994 acrA.3004041.AJ318073.1.793_1990.3994 1 0 539 534 acrA 1197 1197 97.74 acrA.l15.c4.ctg.1 2009 61.7 0 . p . 0 T162A NONSYN 484 486 ACT 1030 1032 GCG 48;48;48 G;C;G,A 38;38;36,1 . b'AcrA is a subunit of the AcrAB multidrug efflux system that in K. pneumoniae, which is encoded by the acrRAB operon.';Klebsiella pneumoniae acrA acrA.3004041.AJ318073.1.793_1990.3994 acrA.3004041.AJ318073.1.793_1990.3994 1 0 539 534 acrA 1197 1197 97.74 acrA.l15.c4.ctg.1 2009 61.7 0 . p . 0 Q175fs FSHIFT 523 523 C 1068 1068 C 42 C 33 . b'AcrA is a subunit of the AcrAB multidrug efflux system that in K. pneumoniae, which is encoded by the acrRAB operon.';Klebsiella pneumoniae acrA acrA.3004041.AJ318073.1.793_1990.3994 acrA.3004041.AJ318073.1.793_1990.3994 1 0 539 534 acrA 1197 1197 97.74 acrA.l15.c4.ctg.1 2009 61.7 0 . p . 0 L179R NONSYN 535 537 CTC 1079 1081 CGC 42;42;42 C;G;C 33;32;31 . b'AcrA is a subunit of the AcrAB multidrug efflux system that in K. pneumoniae, which is encoded by the acrRAB operon.';Klebsiella pneumoniae acrA acrA.3004041.AJ318073.1.793_1990.3994 acrA.3004041.AJ318073.1.793_1990.3994 1 0 539 534 acrA 1197 1197 97.74 acrA.l15.c4.ctg.1 2009 61.7 0 . p . 0 . MULTIPLE 554 555 CG 1097 1098 TT 42;42 T;T 33;32 . b'AcrA is a subunit of the AcrAB multidrug efflux system that in K. pneumoniae, which is encoded by the acrRAB operon.';Klebsiella pneumoniae acrA acrA.3004041.AJ318073.1.793_1990.3994 acrA.3004041.AJ318073.1.793_1990.3994 1 0 539 534 acrA 1197 1197 97.74 acrA.l15.c4.ctg.1 2009 61.7 0 . p . 0 P189T NONSYN 565 567 CCC 1108 1110 ACC 39;40;40 A;C;C 31;32;32 . b'AcrA is a subunit of the AcrAB multidrug efflux system that in K. pneumoniae, which is encoded by the acrRAB operon.';Klebsiella pneumoniae acrA acrA.3004041.AJ318073.1.793_1990.3994 acrA.3004041.AJ318073.1.793_1990.3994 1 0 539 534 acrA 1197 1197 97.74 acrA.l15.c4.ctg.1 2009 61.7 0 . p . 0 V210L NONSYN 628 630 GTG 1171 1173 CTG 47;47;46 C;T;G 34;33;33 . b'AcrA is a subunit of the AcrAB multidrug efflux system that in K. pneumoniae, which is encoded by the acrRAB operon.';Klebsiella pneumoniae acrA acrA.3004041.AJ318073.1.793_1990.3994 acrA.3004041.AJ318073.1.793_1990.3994 1 0 539 534 acrA 1197 1197 97.74 acrA.l15.c4.ctg.1 2009 61.7 0 . p . 0 A234G NONSYN 700 702 GCC 1243 1245 GGC 54;54;58 G;G;C 39;37;40 . b'AcrA is a subunit of the AcrAB multidrug efflux system that in K. pneumoniae, which is encoded by the acrRAB operon.';Klebsiella pneumoniae acrA acrA.3004042.DQ679966.299_1493.3995 acrA.3004042.DQ679966.299_1493.3995 1 0 528 44 acrA_1 1194 159 91.19 acrA_1.l15.c4.ctg.1 355 20.0 0 . p . 0 Q36H NONSYN 106 108 CAG 302 304 CAC 3;3;3 C;A;C 3;3;3 . Enterobacter cloacae acrA;b'AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. cloacae.' acrA.3004042.DQ679966.299_1493.3995 acrA.3004042.DQ679966.299_1493.3995 1 0 528 44 acrA_1 1194 159 91.19 acrA_1.l15.c4.ctg.1 355 20.0 0 . p . 0 A37M NONSYN 109 111 GCG 305 307 ATG 3;3;3 A;T;G 3;3;3 . Enterobacter cloacae acrA;b'AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. cloacae.' acrA.3004042.DQ679966.299_1493.3995 acrA.3004042.DQ679966.299_1493.3995 1 0 528 44 acrA_1 1194 159 91.19 acrA_1.l15.c4.ctg.1 355 20.0 0 . p . 0 V42I NONSYN 124 126 GTT 320 322 ATT 3;3;3 A;T;T 3;3;3 . Enterobacter cloacae acrA;b'AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. cloacae.' acrA.3004042.DQ679966.299_1493.3995 acrA.3004042.DQ679966.299_1493.3995 1 0 528 44 acrA_1 1194 159 91.19 acrA_1.l15.c4.ctg.1 355 20.0 0 . p . 0 E48A NONSYN 142 144 GAA 338 340 GCA 3;3;3 G;C;A 3;3;3 . Enterobacter cloacae acrA;b'AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. cloacae.' acrR.3003373.CP000647.489264_489915.2069 acrR.3003373.CP000647.489264_489915.2069 1 1 27 398 acrR 651 651 99.85 acrR.l6.c4.ctg.1 1331 65.8 1 SNP p M109I 0 . . 325 327 ATG 652 654 ATG 69;69;69 A;T;G 57;54;57 acrR.3003373.CP000647.489264_489915.2069:1:1:M109I:.:b'AcrR is a repressor of the AcrAB-TolC multidrug efflux complex. AcrR mutations result in high level antibiotic resistance.' Klebsiella pneumoniae acrR with mutation conferring multidrug antibiotic resistance acrR.3003373.CP000647.489264_489915.2069 acrR.3003373.CP000647.489264_489915.2069 1 1 27 398 acrR 651 651 99.85 acrR.l6.c4.ctg.1 1331 65.8 1 SNP p Y114F 0 . . 340 342 TAT 667 669 TAT 61;61;66 T;A;T 52;52;56 acrR.3003373.CP000647.489264_489915.2069:1:1:Y114F:.:b'AcrR is a repressor of the AcrAB-TolC multidrug efflux complex. AcrR mutations result in high level antibiotic resistance.' Klebsiella pneumoniae acrR with mutation conferring multidrug antibiotic resistance acrR.3003373.CP000647.489264_489915.2069 acrR.3003373.CP000647.489264_489915.2069 1 1 27 398 acrR 651 651 99.85 acrR.l6.c4.ctg.1 1331 65.8 1 SNP p V165I 0 . . 493 495 GTG 820 822 GTG 69;69;70 G;T;G 58;57;58 acrR.3003373.CP000647.489264_489915.2069:1:1:V165I:.:b'AcrR is a repressor of the AcrAB-TolC multidrug efflux complex. AcrR mutations result in high level antibiotic resistance.' Klebsiella pneumoniae acrR with mutation conferring multidrug antibiotic resistance catB3.3002676.JX101693.1.58200_58833.5450 catB3.3002676.JX101693.1.58200_58833.5450 1 0 16 134 catB3 633 442 100.0 catB3.l15.c4.ctg.1 939 31.5 . . . . . . . . . . . . . . . . . catB3;b'catB3 is a plasmid or chromosome-encoded variant of the cat gene found in Salmonella typhimurium, Acinetobacter baumannii and Escherichia coli' fabG.3004049.U00096.3.1150669_1151404.5523 fabG.3004049.U00096.3.1150669_1151404.5523 1 1 528 42 fabG 735 556 92.27 fabG.l15.c4.ctg.1 765 12.3 0 . p . 0 N2S NONSYN 4 6 AAT 213 215 AGT 11;13;13 A;G;T 8;9;9 . Escherichia coli fabG mutations conferring resistance to triclosan fabG.3004049.U00096.3.1150669_1151404.5523 fabG.3004049.U00096.3.1150669_1151404.5523 1 1 528 42 fabG 735 556 92.27 fabG.l15.c4.ctg.1 765 12.3 0 . p . 0 A26V NONSYN 76 78 GCA 285 287 GTC 14;15;15 G;T;C 10;10;10 . Escherichia coli fabG mutations conferring resistance to triclosan fabG.3004049.U00096.3.1150669_1151404.5523 fabG.3004049.U00096.3.1150669_1151404.5523 1 1 528 42 fabG 735 556 92.27 fabG.l15.c4.ctg.1 765 12.3 0 . p . 0 N40S NONSYN 118 120 AAT 327 329 AGC 17;17;17 A;G;C 12;11;12 . Escherichia coli fabG mutations conferring resistance to triclosan fabG.3004049.U00096.3.1150669_1151404.5523 fabG.3004049.U00096.3.1150669_1151404.5523 1 1 528 42 fabG 735 556 92.27 fabG.l15.c4.ctg.1 765 12.3 0 . p . 0 K72N NONSYN 214 216 AAA 423 425 AAT 17;17;17 A;A;T 12;12;12 . Escherichia coli fabG mutations conferring resistance to triclosan fabG.3004049.U00096.3.1150669_1151404.5523 fabG.3004049.U00096.3.1150669_1151404.5523 1 1 528 42 fabG 735 556 92.27 fabG.l15.c4.ctg.1 765 12.3 0 . p . 0 I73V NONSYN 217 219 ATT 426 428 GTG 17;17;17 G;T;G 12;12;12 . Escherichia coli fabG mutations conferring resistance to triclosan fabG.3004049.U00096.3.1150669_1151404.5523 fabG.3004049.U00096.3.1150669_1151404.5523 1 1 528 42 fabG 735 556 92.27 fabG.l15.c4.ctg.1 765 12.3 0 . p . 0 E101D NONSYN 301 303 GAA 510 512 GAC 20;20;20 G;A;C 13;13;13 . Escherichia coli fabG mutations conferring resistance to triclosan fabG.3004049.U00096.3.1150669_1151404.5523 fabG.3004049.U00096.3.1150669_1151404.5523 1 1 528 42 fabG 735 556 92.27 fabG.l15.c4.ctg.1 765 12.3 0 . p . 0 G146A NONSYN 436 438 GGC 645 647 GCG 10;10;10 G;C;G 8;8;8 . Escherichia coli fabG mutations conferring resistance to triclosan fabG.3004049.U00096.3.1150669_1151404.5523 fabG.3004049.U00096.3.1150669_1151404.5523 1 1 528 42 fabG 735 556 92.27 fabG.l15.c4.ctg.1 765 12.3 1 SNP p Y151V 0 . . 451 453 TAC 660 662 TAC 10;10;9 T;A;C 8;8;7 fabG.3004049.U00096.3.1150669_1151404.5523:1:1:Y151V:.:b'fabG is a 3-oxoacyl-acyl carrier protein reductase involved in lipid metabolism and fatty acid biosynthesis.The bacterial biocide Triclosan blocks the final reduction step in fatty acid elongation, inhibiting biosynthesis. Point mutations in fabG can confer resistance to Triclosan.' Escherichia coli fabG mutations conferring resistance to triclosan gyrA.3003940.AE005674.2.2352231_2354859.5265 gyrA.3003940.AE005674.2.2352231_2354859.5265 1 1 528 192 gyrA_9 2628 398 92.71 gyrA_9.l6.c17.ctg.2 724 40.9 0 . p . 0 S19N NONSYN 55 57 AGC 379 381 AAC 102;100;99 A;A;C 68;67;67 . Shigella flexneri gyrA conferring resistance to fluoroquinolones gyrA.3003940.AE005674.2.2352231_2354859.5265 gyrA.3003940.AE005674.2.2352231_2354859.5265 1 1 528 192 gyrA_9 2628 398 92.71 gyrA_9.l6.c17.ctg.2 724 40.9 0 . p . 0 S83F NONSYN 247 249 TCG 571 573 TTC 16;16;16 T;T;C 14;14;15 . Shigella flexneri gyrA conferring resistance to fluoroquinolones gyrA.3003940.AE005674.2.2352231_2354859.5265 gyrA.3003940.AE005674.2.2352231_2354859.5265 1 1 528 192 gyrA_9 2628 398 92.71 gyrA_9.l6.c17.ctg.2 724 40.9 0 . p . 0 D87A NONSYN 259 261 GAC 583 585 GCC 16;16;16 G;C;C 15;15;15 . Shigella flexneri gyrA conferring resistance to fluoroquinolones gyrA.3003940.AE005674.2.2352231_2354859.5265 gyrA.3003940.AE005674.2.2352231_2354859.5265 1 1 528 192 gyrA_9 2628 398 92.71 gyrA_9.l6.c17.ctg.2 724 40.9 1 SNP p N57K 0 . . 169 171 AAT 493 495 AAT 43;42;42 A;A;T,G 30;29;28,1 gyrA.3003940.AE005674.2.2352231_2354859.5265:1:1:N57K:.:b'Point mutations in Shigella flexneri gyrA observed to confer resistance to fluoroquinolone antibiotics.' Shigella flexneri gyrA conferring resistance to fluoroquinolones gyrA.3004334.AE006468.2.2373709_2376346.5394 gyrA.3004334.AE006468.2.2373709_2376346.5394 1 1 528 210 gyrA_8 2637 344 92.44 gyrA_8.l15.c4.ctg.2 345 6.7 0 . p . 0 N628D NONSYN 1882 1884 AAC 163 165 GAT 8;8;8 G;A;T 4;4;4 . Salmonella enterica gyrA with mutation conferring resistance to triclosan gyrA.3004334.AE006468.2.2373709_2376346.5394 gyrA.3004334.AE006468.2.2373709_2376346.5394 1 1 528 210 gyrA_8 2637 344 92.44 gyrA_8.l15.c4.ctg.2 345 6.7 0 . p . 0 D678E NONSYN 2032 2034 GAC 313 315 GAA 3;3;3 G;A;A 3;3;3 . Salmonella enterica gyrA with mutation conferring resistance to triclosan oqxA.3003922.EU370913.1.46651_47827.5460 oqxA.3003922.EU370913.1.46651_47827.5460 1 0 27 474 oqxA 1176 1176 99.23 oqxA.l6.c4.ctg.1 2013 55.6 . . . . . . . . . . . . . . . . . oqxA;b'RND efflux pump conferring resistance to fluoroquinolone' oqxB.3003923.EU370913.1.47850_51003.5462 oqxB.3003923.EU370913.1.47850_51003.5462 1 0 539 944 oqxB 3153 3153 98.86 oqxB.l15.c4.ctg.1 4068 57.2 0 . p . 0 G148N NONSYN 442 444 GGC 956 958 AAC 56;56;57 A;A;C 45;45;46 . oqxB;b'RND efflux pump conferring resistance to fluoroquinolone' oqxB.3003923.EU370913.1.47850_51003.5462 oqxB.3003923.EU370913.1.47850_51003.5462 1 0 539 944 oqxB 3153 3153 98.86 oqxB.l15.c4.ctg.1 4068 57.2 0 . p . 0 G540S NONSYN 1618 1620 GGC 2132 2134 AGC 62;62;62 A;G;C 45;45;45 . oqxB;b'RND efflux pump conferring resistance to fluoroquinolone' oqxB.3003923.EU370913.1.47850_51003.5462 oqxB.3003923.EU370913.1.47850_51003.5462 1 0 539 944 oqxB 3153 3153 98.86 oqxB.l15.c4.ctg.1 4068 57.2 0 . p . 0 D749E NONSYN 2245 2247 GAT 2759 2761 GAG 64;64;64 G;A;G,C 49;47;49,1 . oqxB;b'RND efflux pump conferring resistance to fluoroquinolone' oqxB.3003923.EU370913.1.47850_51003.5462 oqxB.3003923.EU370913.1.47850_51003.5462 1 0 539 944 oqxB 3153 3153 98.86 oqxB.l15.c4.ctg.1 4068 57.2 0 . p . 0 Y783F NONSYN 2347 2349 TAC 2861 2863 TTC 55;55;54 T;T,G;C 45;43,1;43 . oqxB;b'RND efflux pump conferring resistance to fluoroquinolone' oqxB.3003923.EU370913.1.47850_51003.5462 oqxB.3003923.EU370913.1.47850_51003.5462 1 0 539 944 oqxB 3153 3153 98.86 oqxB.l15.c4.ctg.1 4068 57.2 0 . p . 0 P1049L NONSYN 3145 3147 CCC 3659 3661 CTC 12;12;11 C;T;C 11;10;10 . oqxB;b'RND efflux pump conferring resistance to fluoroquinolone' ramR.3003380.CP000647.1.622039_622621.4572 ramR.3003380.CP000647.1.622039_622621.4572 1 1 27 392 ramR_1 582 582 100.0 ramR_1.l15.c4.ctg.1 1721 53.5 1 SNP p K5E 0 . . 13 15 AAG 455 457 AAG 139;139;140 A;A;G 102;100;101 ramR.3003380.CP000647.1.622039_622621.4572:1:1:K5E:.:b'RamR is a repressor that regulates RamA expression. Mutations lead to the upregulation of AcrAB, which is positively regulated by RamA.' Klebsiella pneumoniae ramR mutants ramR.3003380.CP000647.1.622039_622621.4572 ramR.3003380.CP000647.1.622039_622621.4572 1 1 27 392 ramR_1 582 582 100.0 ramR_1.l15.c4.ctg.1 1721 53.5 1 SNP p A16D 0 . . 46 48 GCT 488 490 GCT 154;154;154 G;C;T 106;107;106 ramR.3003380.CP000647.1.622039_622621.4572:1:1:A16D:.:b'RamR is a repressor that regulates RamA expression. Mutations lead to the upregulation of AcrAB, which is positively regulated by RamA.' Klebsiella pneumoniae ramR mutants ramR.3003380.CP000647.1.622039_622621.4572 ramR.3003380.CP000647.1.622039_622621.4572 1 1 27 392 ramR_1 582 582 100.0 ramR_1.l15.c4.ctg.1 1721 53.5 1 SNP p A19V 0 . . 55 57 GCG 497 499 GCG 147;147;147 G,T;C;G 106,1;107;106 ramR.3003380.CP000647.1.622039_622621.4572:1:1:A19V:.:b'RamR is a repressor that regulates RamA expression. Mutations lead to the upregulation of AcrAB, which is positively regulated by RamA.' Klebsiella pneumoniae ramR mutants ramR.3003380.CP000647.1.622039_622621.4572 ramR.3003380.CP000647.1.622039_622621.4572 1 1 27 392 ramR_1 582 582 100.0 ramR_1.l15.c4.ctg.1 1721 53.5 1 SNP p T43M 0 . . 127 129 ACG 569 571 ACG 120;115;115 A;C,T;G 94;91,1;93 ramR.3003380.CP000647.1.622039_622621.4572:1:1:T43M:.:b'RamR is a repressor that regulates RamA expression. Mutations lead to the upregulation of AcrAB, which is positively regulated by RamA.' Klebsiella pneumoniae ramR mutants ramR.3003380.CP000647.1.622039_622621.4572 ramR.3003380.CP000647.1.622039_622621.4572 1 1 27 392 ramR_1 582 582 100.0 ramR_1.l15.c4.ctg.1 1721 53.5 1 SNP p I88N 0 . . 262 264 ATC 704 706 ATC 92;90;90 A;T;C 71;72;71 ramR.3003380.CP000647.1.622039_622621.4572:1:1:I88N:.:b'RamR is a repressor that regulates RamA expression. Mutations lead to the upregulation of AcrAB, which is positively regulated by RamA.' Klebsiella pneumoniae ramR mutants ramR.3003380.CP000647.1.622039_622621.4572 ramR.3003380.CP000647.1.622039_622621.4572 1 1 27 392 ramR_1 582 582 100.0 ramR_1.l15.c4.ctg.1 1721 53.5 1 SNP p G96D 0 . . 286 288 GGC 728 730 GGC 85;85;82 G;G;C 66;65;65 ramR.3003380.CP000647.1.622039_622621.4572:1:1:G96D:.:b'RamR is a repressor that regulates RamA expression. Mutations lead to the upregulation of AcrAB, which is positively regulated by RamA.' Klebsiella pneumoniae ramR mutants ramR.3003380.CP000647.1.622039_622621.4572 ramR.3003380.CP000647.1.622039_622621.4572 1 1 27 392 ramR_1 582 582 100.0 ramR_1.l15.c4.ctg.1 1721 53.5 1 SNP p T162I 0 . . 484 486 ACC 926 928 ACC 118;118;118 A;C;C 84;84;83 ramR.3003380.CP000647.1.622039_622621.4572:1:1:T162I:.:b'RamR is a repressor that regulates RamA expression. Mutations lead to the upregulation of AcrAB, which is positively regulated by RamA.' Klebsiella pneumoniae ramR mutants rmtC.3000861.KJ476816.1.79_925.3396 rmtC.3000861.KJ476816.1.79_925.3396 1 0 27 254 rmtC 846 846 100.0 rmtC.l15.c17.ctg.1 1579 36.8 . . . . . . . . . . . . . . . . . b'RmtC is a rRNA methyltransferase found in Proteus mirabilis with high level resistance to similar to aminoglycosides, with the exception of non-4,6-disubstituted deoxystreptamines (streptomycin and neomycin). It has also been isolated in Salmonella enterica ser. Virchow. It is hypothesized to methylate G1405, like related methyltransferases RmtA, RmtB, and ArmA.';rmtC rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 608 94.08 rpoB.l15.c4.ctg.1 1275 30.1 0 . p . 0 Q83K NONSYN 247 249 CAG 912 914 AAA 55;54;54 A;A;A 41;41;41 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 608 94.08 rpoB.l15.c4.ctg.1 1275 30.1 1 SNP p V146F 0 . . 436 438 GTT 1101 1103 GTT 13;12;12 G;T;T 13;12;12 rpoB.3003288.BA000007.3.4990267_4994296.5493:1:1:V146F:.:b'Point mutations that occurs in Escherichia coli rpoB resulting in resistance to rifampicin' Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 V242I NONSYN 724 726 GTG 16 18 ATT 2;2;2 A;T;T 2;2;2 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 V282I NONSYN 844 846 GTC 136 138 ATC 3;3;3 A;T;C 3;3;3 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 L284H NONSYN 850 852 CTG 142 144 CAT 3;3;3 C;A;T 3;3;3 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 V297A NONSYN 889 891 GTT 181 183 GCG 3;3;3 G;C;G 3;3;3 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 S305A NONSYN 913 915 TCT 205 207 GCG 5;5;5 G;C;G 5;5;5 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 A312P NONSYN 934 936 GCA 226 228 CCG 6;6;6 C;C;G 5;6;6 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 L351V NONSYN 1051 1053 TTA 343 345 GTA 7;7;7 G;T;A 7;7;7 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 E412D NONSYN 1234 1236 GAA 526 528 GAC 26;26;25 G;A;C 22;22;22 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 D427E NONSYN 1279 1281 GAT 571 573 GAA 30;30;30 G;A;A 27;27;27 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 D596N NONSYN 1786 1788 GAC 1078 1080 AAC 60;63;64 A;A;C 46;48;50 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 E626N NONSYN 1876 1878 GAA 1168 1170 AAC 63;63;63 A;A;C 48;48;48 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 V723T NONSYN 2167 2169 GTC 1459 1461 ACC 53;53;52 A;C;C 43;42;42 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 V777I NONSYN 2329 2331 GTT 1621 1623 ATT 24;24;24 A;T;T 16;18;16 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 R976Y NONSYN 2926 2928 CGT 2218 2220 TAC 22;21;21 T;A;C 18;17;17 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 A981S NONSYN 2941 2943 GCC 2233 2235 TCC 23;23;23 T;C;C 18;18;18 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 Y1087H NONSYN 3259 3261 TAC 2551 2553 CAC 16;16;16 C;A;C 11;11;11 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 E1089A NONSYN 3265 3267 GAA 2557 2559 GCT 17;17;17 G;C;T 12;12;12 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 S1162N NONSYN 3484 3486 AGT 2776 2778 AAT 30;30;32 A;A;T 21;20;21 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 M1170L NONSYN 3508 3510 ATG 2800 2802 CTG 34;34;34 C;T;G 22;24;22 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 K1200Q NONSYN 3598 3600 AAA 2890 2892 CAG 37;37;37 C;A;G 27;27;26 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 R1211T NONSYN 3631 3633 CGC 2923 2925 ACC 36;33;33 A;C;C 27;25;25 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 0 . p . 0 Y1213F NONSYN 3637 3639 TAC 2929 2931 TTT 34;34;35 T;T;T 25;25;25 . Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 1 SNP p Q513L 0 . . 1537 1539 CAG 829 831 CAG 77;77;77 C;A;G 56;56;56 rpoB.3003288.BA000007.3.4990267_4994296.5493:1:1:Q513L:.:b'Point mutations that occurs in Escherichia coli rpoB resulting in resistance to rifampicin' Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 1 SNP p Q513P 0 . . 1537 1539 CAG 829 831 CAG 77;77;77 C;A;G 56;56;56 rpoB.3003288.BA000007.3.4990267_4994296.5493:1:1:Q513P:.:b'Point mutations that occurs in Escherichia coli rpoB resulting in resistance to rifampicin' Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 1 SNP p H526Y 0 . . 1576 1578 CAC 868 870 CAC 84;83;83 C;A,G;C 59;58,1;59 rpoB.3003288.BA000007.3.4990267_4994296.5493:1:1:H526Y:.:b'Point mutations that occurs in Escherichia coli rpoB resulting in resistance to rifampicin' Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 1 SNP p R529C 0 . . 1585 1587 CGT 877 879 CGT 85;86;86 C;G;T 60;61;61 rpoB.3003288.BA000007.3.4990267_4994296.5493:1:1:R529C:.:b'Point mutations that occurs in Escherichia coli rpoB resulting in resistance to rifampicin' Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 1 SNP p R529S 0 . . 1585 1587 CGT 877 879 CGT 85;86;86 C;G;T 60;61;61 rpoB.3003288.BA000007.3.4990267_4994296.5493:1:1:R529S:.:b'Point mutations that occurs in Escherichia coli rpoB resulting in resistance to rifampicin' Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 1 SNP p S531F 0 . . 1591 1593 TCC 883 885 TCC 89;87;86 T;C;C,T 62;61;59,1 rpoB.3003288.BA000007.3.4990267_4994296.5493:1:1:S531F:.:b'Point mutations that occurs in Escherichia coli rpoB resulting in resistance to rifampicin' Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 1 SNP p L533P 0 . . 1597 1599 CTC 889 891 CTC 87;87;87 C;T;C 61;59;61 rpoB.3003288.BA000007.3.4990267_4994296.5493:1:1:L533P:.:b'Point mutations that occurs in Escherichia coli rpoB resulting in resistance to rifampicin' Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 1 SNP p P564L 0 . . 1690 1692 CCT 982 984 CCT 67;67;67 C;C;T 51;51;53 rpoB.3003288.BA000007.3.4990267_4994296.5493:1:1:P564L:.:b'Point mutations that occurs in Escherichia coli rpoB resulting in resistance to rifampicin' Escherichia coli rpoB mutants conferring resistance to rifampicin rpoB.3003288.BA000007.3.4990267_4994296.5493 rpoB.3003288.BA000007.3.4990267_4994296.5493 1 1 513 678 rpoB 4029 3321 93.44 rpoB.l15.c4.ctg.2 3739 33.7 1 SNP p R687H 0 . . 2059 2061 CGT 1351 1353 CGT 58;58;58 C;G;T 50;49;49 rpoB.3003288.BA000007.3.4990267_4994296.5493:1:1:R687H:.:b'Point mutations that occurs in Escherichia coli rpoB resulting in resistance to rifampicin' Escherichia coli rpoB mutants conferring resistance to rifampicin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 G179A SNP 179 179 G 266 266 A 723 A 525 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 C191T SNP 191 191 C 278 278 T 724 T,C 512,2 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 C254T SNP 254 254 C 341 341 T 666 T,C 513,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 C302T SNP 302 302 C 389 389 T 670 T 521 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 A406G SNP 406 406 A 493 493 G 713 G,C 536,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 A410G SNP 410 410 A 497 497 G 699 G,A,T 341,190,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 T412C SNP 412 412 T 499 499 C 706 C 533 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 C672T SNP 672 672 C 759 759 T 749 T,C 548,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 G720A SNP 720 720 G 807 807 A 693 A,T,G 519,4,2 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 A722C SNP 722 722 A 809 809 C 689 C 528 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 A893T SNP 893 893 A 980 980 T 679 T 519 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 T1069C SNP 1069 1069 T 1156 1156 C 819 C 590 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 C1074A SNP 1074 1074 C 1161 1161 A 820 A 590 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 A1086T SNP 1086 1086 A 1173 1173 T 813 T 584 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 C1087T SNP 1087 1087 C 1174 1174 T 805 T,C 384,193 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 A1091G SNP 1091 1091 A 1178 1178 G 811 G,T,A 572,2,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 A1112G SNP 1112 1112 A 1199 1199 G 796 G,A 571,2 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 T1138C SNP 1138 1138 T 1225 1225 C 733 C,T 554,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 T1273A SNP 1273 1273 T 1360 1360 A 584 A 454 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 T1288C SNP 1288 1288 T 1375 1375 C 565 C 443 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 A1293T SNP 1293 1293 A 1380 1380 T 571 T,C 449,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 A1296T SNP 1296 1296 A 1383 1383 T 569 T,A,C 402,43,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 A1328T SNP 1328 1328 A 1415 1415 T 584 T,A 464,2 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 T1347A SNP 1347 1347 T 1434 1434 A 588 A,C,T 456,1,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 G1363A SNP 1363 1363 G 1450 1450 A 605 A,G 154,301 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 C1379T SNP 1379 1379 C 1466 1466 T 716 T 550 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 A1443G SNP 1443 1443 A 1530 1530 G 857 G,T 611,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 G1451C SNP 1451 1451 G 1538 1538 C 851 C 610 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 A1454G SNP 1454 1454 A 1541 1541 G 846 G,C 605,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 C1457. DEL 1457 1457 C 1543 1543 G 831 G,T,A 600,1,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 G1466. DEL 1466 1466 G 1551 1551 T 820 T,A 604,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 C1470T SNP 1470 1470 C 1555 1555 T 822 T 605 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 C1471G SNP 1471 1471 C 1556 1556 G 823 G,C 605,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 T1474C SNP 1474 1474 T 1559 1559 C 821 C,G 598,2 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 . n . 0 T1480C SNP 1480 1480 T 1565 1565 C 820 C 590 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 1 SNP n C1065U 0 . . 1065 1065 C 1152 1152 C 819 C,T 591,1 rrsD.3003512.AE006468.3570463_3572006.3227:0:0:C1065U:.:b'Point mutations in the helix 34 region of the rrsD 16S rRNA gene of Salmonella enterica serovar Typhimurium can confer resistance to spectinomycin' Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 1 SNP n C1192U 0 . . 1192 1192 C 1279 1279 C 713 C 523 rrsD.3003512.AE006468.3570463_3572006.3227:0:0:C1192U:.:b'Point mutations in the helix 34 region of the rrsD 16S rRNA gene of Salmonella enterica serovar Typhimurium can confer resistance to spectinomycin' Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 HET . . . T526A . 526 526 T 613 613 T 821 T,A 441,136 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 HET . . . C527G,T,A . 527 527 C 614 614 C 821 C,G,T,A 434,138,1,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 HET . . . C559T . 559 559 C 646 646 C 781 C,T 510,63 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 HET . . . C1071A,T,G . 1071 1071 C 1158 1158 C 806 C,A,T,G 240,342,1,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 HET . . . C1072T . 1072 1072 T 1159 1159 C 807 C,T 310,274 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 HET . . . A1073G,T . 1073 1073 G 1160 1160 A 807 A,G,T 310,269,2 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 HET . . . G1234A . 1234 1234 G 1321 1321 G 654 G,A 418,54 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 HET . . . G536C . 536 536 G 623 623 G 826 G,C 440,134 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 HET . . . G409T,A,C . 409 409 T 496 496 G 699 G,T,A,C 462,72,1,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 HET . . . A537T . 537 537 A 624 624 A 826 A,T 444,136 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 HET . . . G926A,T . 926 926 G 1013 1013 G 698 G,A,T 474,65,2 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin rrsD.3003512.AE006468.3570463_3572006.3227 rrsD.3003512.AE006468.3570463_3572006.3227 0 0 659 6088 rrsB+ 1544 1544 97.22 rrsB+.l15.c17.ctg.1 1693 765.7 0 HET . . . A1089C,T,G . 1089 1089 A 1176 1176 A 807 A,C,T,G 312,194,74,1 . Salmonella enterica 16S rRNA (rrsD) mutation conferring resistance to spectinomycin sul1.3000410.JF969163.1053_1893.340 sul1.3000410.JF969163.1053_1893.340 1 0 27 360 sul1 840 840 99.88 sul1.l15.c17.ctg.1 1783 43.9 . . . . . . . . . . . . . . . . . b'Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons.';sul1