Mercurial > repos > iuc > medaka_consensus_pipeline
changeset 13:72b5e9dda577 draft
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/medaka commit 52289bc7b99bfa8a3bda46cb35cea98399419dab"
| author | iuc |
|---|---|
| date | Thu, 18 Nov 2021 20:01:28 +0000 |
| parents | 0e9e7fcdd543 |
| children | cb34f00cc10f |
| files | convert_VCF_info_fields.py macros.xml medaka_consensus.xml test-data/basecalls.fastq test-data/basecalls.fastq.gz |
| diffstat | 5 files changed, 113 insertions(+), 558 deletions(-) [+] |
line wrap: on
line diff
--- a/convert_VCF_info_fields.py Fri Sep 17 20:23:12 2021 +0000 +++ b/convert_VCF_info_fields.py Thu Nov 18 20:01:28 2021 +0000 @@ -24,10 +24,10 @@ def parseInfoField(info): - info_fields = info.split(';') + info_fields = info.split(";") info_dict = OrderedDict() for info_field in info_fields: - code, val = info_field.split('=') + code, val = info_field.split("=") info_dict[code] = val return info_dict @@ -40,7 +40,7 @@ and multiple alternate alleles with simple ref, alt allele counterparts. """ - in_vcf = open(in_vcf_filepath, 'r') + in_vcf = open(in_vcf_filepath, "r") # medaka INFO fields that do not make sense after splitting of # multi-allelic records # DP will be overwritten with the value of DPSP because medaka tools @@ -48,8 +48,8 @@ # (https://github.com/nanoporetech/medaka/issues/192). # DPS, which is as unreliable as DP, gets skipped and the code # calculates the spanning reads equivalent DPSPS instead. - to_skip = {'SC', 'SR', 'AR', 'DP', 'DPSP', 'DPS'} - struct_meta_pat = re.compile('##(.+)=<ID=([^,]+)(,.+)?>') + to_skip = {"SC", "SR", "AR", "DP", "DPSP", "DPS"} + struct_meta_pat = re.compile("##(.+)=<ID=([^,]+)(,.+)?>") header_lines = [] contig_ids = set() contig_ids_simple = set() @@ -59,8 +59,8 @@ # - redundant contig information while True: line = in_vcf.readline() - if line[:2] != '##': - assert line.startswith('#CHROM') + if line[:2] != "##": + assert line.startswith("#CHROM") break if line in header_lines: # the annotate tool may generate lines already written by @@ -69,12 +69,12 @@ match = struct_meta_pat.match(line) if match: match_type, match_id, match_misc = match.groups() - if match_type == 'INFO': - if match_id == 'DPSP': - line = line.replace('DPSP', 'DP') + if match_type == "INFO": + if match_id == "DPSP": + line = line.replace("DPSP", "DP") elif match_id in to_skip: continue - elif match_type == 'contig': + elif match_type == "contig": contig_ids.add(match_id) if not match_misc: # the annotate tools writes its own contig info, @@ -87,7 +87,7 @@ # Lets check the above assumption about each ID-only contig line # having a more complete counterpart. assert not (contig_ids_simple - contig_ids) - header_lines.insert(1, '##convert_VCF_info_fields=0.2\n') + header_lines.insert(1, "##convert_VCF_info_fields=0.2\n") header_lines += [ '##INFO=<ID=DPSPS,Number=2,Type=Integer,Description="Depth of spanning reads by strand">\n', '##INFO=<ID=AF,Number=1,Type=Float,Description="Spanning Reads Allele Frequency">\n', @@ -96,47 +96,34 @@ '##INFO=<ID=SB,Number=1,Type=Integer,Description="Phred-scaled strand bias of spanning reads at this position">\n', '##INFO=<ID=DP4,Number=4,Type=Integer,Description="Counts for ref-forward bases, ref-reverse, alt-forward and alt-reverse bases in spanning reads">\n', '##INFO=<ID=AS,Number=4,Type=Integer,Description="Total alignment score to ref and alt allele of spanning reads by strand (ref fwd, ref rev, alt fwd, alt rev) aligned with parasail match 5, mismatch -4, open 5, extend 3">\n', - line + line, ] - with open(out_vcf_filepath, 'w') as out_vcf: + with open(out_vcf_filepath, "w") as out_vcf: out_vcf.writelines(header_lines) for line in in_vcf: - fields = line.split('\t') + fields = line.split("\t") info_dict = parseInfoField(fields[7]) - sr_list = [int(x) for x in info_dict["SR"].split(',')] - sc_list = [int(x) for x in info_dict["SC"].split(',')] + sr_list = [int(x) for x in info_dict["SR"].split(",")] + sc_list = [int(x) for x in info_dict["SC"].split(",")] if len(sr_list) != len(sc_list): - print( - 'WARNING - SR and SC are different lengths, ' - 'skipping variant' - ) + print("WARNING - SR and SC are different lengths, " "skipping variant") print(line.strip()) # Print the line for debugging purposes continue - variant_list = fields[4].split(',') - dpsp = int(info_dict['DPSP']) + variant_list = fields[4].split(",") + dpsp = int(info_dict["DPSP"]) ref_fwd, ref_rev = 0, 1 - dpspf, dpspr = (int(x) for x in info_dict['AR'].split(',')) + dpspf, dpspr = (int(x) for x in info_dict["AR"].split(",")) for i in range(0, len(sr_list), 2): dpspf += sr_list[i] dpspr += sr_list[i + 1] for j, i in enumerate(range(2, len(sr_list), 2)): - dp4 = ( - sr_list[ref_fwd], - sr_list[ref_rev], - sr_list[i], - sr_list[i + 1] - ) + dp4 = (sr_list[ref_fwd], sr_list[ref_rev], sr_list[i], sr_list[i + 1]) dp2x2 = [[dp4[0], dp4[1]], [dp4[2], dp4[3]]] _, p_val = scipy.stats.fisher_exact(dp2x2) sb = pval_to_phredqual(p_val) - as_ = ( - sc_list[ref_fwd], - sc_list[ref_rev], - sc_list[i], - sc_list[i + 1] - ) + as_ = (sc_list[ref_fwd], sc_list[ref_rev], sc_list[i], sc_list[i + 1]) info = [] for code in info_dict: @@ -145,31 +132,31 @@ val = info_dict[code] info.append("%s=%s" % (code, val)) - info.append('DP=%d' % dpsp) - info.append('DPSPS=%d,%d' % (dpspf, dpspr)) + info.append("DP=%d" % dpsp) + info.append("DPSPS=%d,%d" % (dpspf, dpspr)) if dpsp == 0: - info.append('AF=NaN') + info.append("AF=NaN") else: af = (dp4[2] + dp4[3]) / dpsp - info.append('AF=%.6f' % af) + info.append("AF=%.6f" % af) if dpspf == 0: - info.append('FAF=NaN') + info.append("FAF=NaN") else: faf = dp4[2] / dpspf - info.append('FAF=%.6f' % faf) + info.append("FAF=%.6f" % faf) if dpspr == 0: - info.append('RAF=NaN') + info.append("RAF=NaN") else: raf = dp4[3] / dpspr - info.append('RAF=%.6f' % raf) - info.append('SB=%d' % sb) - info.append('DP4=%d,%d,%d,%d' % dp4) - info.append('AS=%d,%d,%d,%d' % as_) - new_info = ';'.join(info) + info.append("RAF=%.6f" % raf) + info.append("SB=%d" % sb) + info.append("DP4=%d,%d,%d,%d" % dp4) + info.append("AS=%d,%d,%d,%d" % as_) + new_info = ";".join(info) fields[4] = variant_list[j] fields[7] = new_info - out_vcf.write('\t'.join(fields)) + out_vcf.write("\t".join(fields)) in_vcf.close()
--- a/macros.xml Fri Sep 17 20:23:12 2021 +0000 +++ b/macros.xml Thu Nov 18 20:01:28 2021 +0000 @@ -1,10 +1,10 @@ -<?xml version="1.0"?> <macros> - <token name="@TOOL_VERSION@">1.3.2</token> + <token name="@TOOL_VERSION@">1.4.4</token> + <token name="@VERSION_SUFFIX@">0</token> <token name="@PROFILE@">20.01</token> <xml name="bio_tools"> <xrefs> - <xref type="bio.tools">khmer</xref> + <xref type="bio.tools">medaka</xref> </xrefs> </xml> <xml name="requirements"> @@ -52,22 +52,51 @@ <param argument="@ARGUMENT@" type="integer" value="100" min="1" label="Set inference batch size"/> </xml> <xml name="model" token_argument="-m" token_label="Select model"> - <param argument="@ARGUMENT@" type="select" label="@LABEL@"> + <param argument="@ARGUMENT@" type="select" label="@LABEL@" help="For best results it is important to specify the correct model, + according to the basecaller used. Medaka models are named to indicate i) the pore type, ii) the sequencing device (MinION + or PromethION), iii) the basecaller variant, and iv) the basecaller version"> + <option value="r103_fast_g507">r103_fast_g507</option> + <option value="r103_fast_snp_g507">r103_fast_snp_g507</option> + <option value="r103_fast_variant_g507">r103_fast_variant_g507</option> + <option value="r103_hac_g507">r103_hac_g507</option> + <option value="r103_hac_snp_g507">r103_hac_snp_g507</option> + <option value="r103_hac_variant_g507">r103_hac_variant_g507</option> <option value="r103_min_high_g345">r103_min_high_g345</option> <option value="r103_min_high_g360">r103_min_high_g360</option> <option value="r103_prom_high_g360">r103_prom_high_g360</option> <option value="r103_prom_snp_g3210">r103_prom_snp_g3210</option> <option value="r103_prom_variant_g3210">r103_prom_variant_g3210</option> + <option value="r103_sup_g507">r103_sup_g507</option> + <option value="r103_sup_snp_g507">r103_sup_snp_g507</option> + <option value="r103_sup_variant_g507">r103_sup_variant_g507</option> + <option value="r104_e81_fast_g5015">r104_e81_fast_g5015</option> + <option value="r104_e81_hac_g5015">r104_e81_hac_g5015</option> + <option value="r104_e81_sup_g5015">r104_e81_sup_g5015</option> <option value="r10_min_high_g303">r10_min_high_g303</option> <option value="r10_min_high_g340">r10_min_high_g340</option> <option value="r941_min_fast_g303">r941_min_fast_g303</option> + <option value="r941_min_fast_g507">r941_min_fast_g507</option> + <option value="r941_min_fast_snp_g507">r941_min_fast_snp_g507</option> + <option value="r941_min_fast_variant_g507">r941_min_fast_variant_g507</option> + <option value="r941_min_hac_g507">r941_min_hac_g507</option> + <option value="r941_min_hac_snp_g507">r941_min_hac_snp_g507</option> + <option value="r941_min_hac_variant_g507">r941_min_hac_variant_g507</option> <option value="r941_min_high_g303">r941_min_high_g303</option> <option value="r941_min_high_g330">r941_min_high_g330</option> <option value="r941_min_high_g340_rle">r941_min_high_g340_rle</option> <option value="r941_min_high_g344">r941_min_high_g344</option> <option value="r941_min_high_g351">r941_min_high_g351</option> <option value="r941_min_high_g360" selected="true">r941_min_high_g360</option> + <option value="r941_min_sup_g507">r941_min_sup_g507</option> + <option value="r941_min_sup_snp_g507">r941_min_sup_snp_g507</option> + <option value="r941_min_sup_variant_g507">r941_min_sup_variant_g507</option> <option value="r941_prom_fast_g303">r941_prom_fast_g303</option> + <option value="r941_prom_fast_g507">r941_prom_fast_g507</option> + <option value="r941_prom_fast_snp_g507">r941_prom_fast_snp_g507</option> + <option value="r941_prom_fast_variant_g507">r941_prom_fast_variant_g507</option> + <option value="r941_prom_hac_g507">r941_prom_hac_g507</option> + <option value="r941_prom_hac_snp_g507">r941_prom_hac_snp_g507</option> + <option value="r941_prom_hac_variant_g507">r941_prom_hac_variant_g507</option> <option value="r941_prom_high_g303">r941_prom_high_g303</option> <option value="r941_prom_high_g330">r941_prom_high_g330</option> <option value="r941_prom_high_g344">r941_prom_high_g344</option> @@ -76,6 +105,9 @@ <option value="r941_prom_snp_g303">r941_prom_snp_g303</option> <option value="r941_prom_snp_g322">r941_prom_snp_g322</option> <option value="r941_prom_snp_g360">r941_prom_snp_g360</option> + <option value="r941_prom_sup_g507">r941_prom_sup_g507</option> + <option value="r941_prom_sup_snp_g507">r941_prom_sup_snp_g507</option> + <option value="r941_prom_sup_variant_g507">r941_prom_sup_variant_g507</option> <option value="r941_prom_variant_g303">r941_prom_variant_g303</option> <option value="r941_prom_variant_g322">r941_prom_variant_g322</option> <option value="r941_prom_variant_g360">r941_prom_variant_g360</option> @@ -111,6 +143,28 @@ This task is performed using neural networks applied from a pileup of individual sequencing reads against a draft assembly. It outperforms graph-based methods operating on basecalled data, and can be competitive with state-of-the-art signal-based methods, whilst being much faster. ]]></token> + + <token name="@MODELS@"><![CDATA[ + +---- + +.. class:: infomark + +**Models** + +For best results it is important to specify the correct model, -m in the above, according to the basecaller used. Allowed values can be found by running medaka tools list\_models. + +Medaka models are named to indicate i) the pore type, ii) the sequencing device (MinION or PromethION), iii) the basecaller variant, and iv) the basecaller version, with the format: + + :: + + {pore}_{device}_{caller variant}_{caller version} + +For example the model named r941_min_fast_g303 should be used with data from MinION (or GridION) R9.4.1 flowcells using the fast Guppy basecaller version 3.0.3. By contrast the model +r941_prom_hac_g303 should be used with PromethION data and the high accuracy basecaller (termed "hac" in Guppy configuration files). Where a version of Guppy has been used without an exactly corresponding medaka model, the medaka model with the highest version equal to or less than the guppy version should be selected. + + ]]></token> + <token name="@REFERENCES@"><![CDATA[ More information are available in the `manual <https://nanoporetech.github.io/medaka/index.html>`_ and `github <https://github.com/nanoporetech/medaka>`_. ]]></token>
--- a/medaka_consensus.xml Fri Sep 17 20:23:12 2021 +0000 +++ b/medaka_consensus.xml Thu Nov 18 20:01:28 2021 +0000 @@ -1,4 +1,4 @@ -<tool id="medaka_consensus_pipeline" name="medaka consensus pipeline" version="@TOOL_VERSION@+galaxy0" profile="@PROFILE@"> +<tool id="medaka_consensus_pipeline" name="medaka consensus pipeline" version="@TOOL_VERSION@+galaxy@VERSION_SUFFIX@" profile="@PROFILE@"> <description>Assembly polishing via neural networks</description> <macros> <import>macros.xml</import> @@ -55,7 +55,7 @@ <tests> <!-- #1 default --> <test expect_num_outputs="3"> - <param name="i" value="basecalls.fastq"/> + <param name="i" value="basecalls.fastq.gz"/> <param name="d" value="assembly.fasta"/> <output name="out_consensus"> <assert_contents> @@ -71,13 +71,13 @@ </output> <output name="out_calls"> <assert_contents> - <has_size value="343197" delta="100"/> + <has_size value="343341" delta="100"/> </assert_contents> </output> </test> <!-- #2 --> <test expect_num_outputs="5"> - <param name="i" value="basecalls.fastq"/> + <param name="i" value="basecalls.fastq.gz"/> <param name="d" value="assembly.fasta"/> <param name="m" value="r941_min_fast_g303"/> <param name="b" value="99"/> @@ -95,7 +95,7 @@ </output> <output name="out_calls"> <assert_contents> - <has_size value="343197" delta="100"/> + <has_size value="343340" delta="100"/> </assert_contents> </output> <output name="out_log"> @@ -119,10 +119,18 @@ The *medaka_consensus* pipeline performs assembly polishing via neural networks. +---- + +.. class:: infomark + **Input** An *assembly* in .fasta format and *basecalls* in .fasta or .fastq format are required. See `Creating a Draft Assembly <https://nanoporetech.github.io/medaka/walkthrough.html#basecalling-and-draft-assembly>`_ for a detailed example of one method of obtaining these. +---- + +.. class:: infomark + **Output** - Consensus polished assembly (FASTA) @@ -132,6 +140,12 @@ - Variants: VCF of changes (VCF) - Polished: BED file of polished regions (BED) +@MODELS@ + +---- + +.. class:: infomark + **References** @REFERENCES@
--- a/test-data/basecalls.fastq Fri Sep 17 20:23:12 2021 +0000 +++ /dev/null Thu Jan 01 00:00:00 1970 +0000 @@ -1,500 +0,0 @@ -@215f1e0c-27d1-4446-bca5-cb0fd6a8c054 -TTGCAGTATCTGCGTCAGAATCGCATTCCAGCCGCAGGTGTTCAGCGGTGCGTACAATTACAGCATTATGTTAAATTTTATAATTGTCTTTAGTCATTGCGCTATGATTTGTAGGTGGAGTTGTTTCATATTTTGATATAAATTCTTTTATCTCACCAAACAGTCATCGTCAGTATCAATGGTTTTGTTCTTCATTGATATTACCTATTCTAGAATCTGATTCCTTGTACAACTAAGGTAAACTTGAACTTTGCTTTCTTTTCATTATTTGGGTAAGCGTAATGATGTAGGATCTAGGATATATCTATAATAATAATTCTTGTTCTTTTTTTATTTTATTGAATATGAATCAATACCTGTCTAAGCACACCTCTTTCTTACGCGTGAGCAATGGTTAGATGGATCTTCTGGCGGCCTTGCGCCATTCCTGTTTGTTC -+ -?B4-)&'%<ABC>:883110,;*-$/+%)(.(($$#%&$$#%14+6-/=1@5@A>GE@F@<B8B..0F>?AA13EJHTIDHBDAJB@BOM908=B;=>49/(?>>?>?@?(004?C57/9<B>DEEE@@@C?=>=<912+,*'1/1396;78+&$&,15(85::C@>BA>9(,</(B:;G?B;@K=<HF?JF5**+&&0/#%$;>BCB=(4<.=91<4@ADC9:AC$=9>555=3412;6;+=>?@>2$%+839@BH=CAOHFCI<.98<-0/*$%)0**()(')&$)$474)+/,'267432&&'&''''$%&'*')>?C3=;467===95489G:./5229,$$&$(&&$%%(''')+8%/0%.-%0$')&'*=566(-(685''57./4%)44+/*$$$'42:;6($$##$$$'-0(%67112$$'$())'7;: -@baf1c4f7-8f02-4c92-be5f-0431ca399c18 -GGTATTACTTCGTTCAGTTACGTATTGCTGCGCGCACTCTCTGTCGTCGGCAGCGTCAGATGTGTATAAGAGACAGCAAGACGATAGTTACCGGATAAGGCGCAGCGGTCGGGCTGAACAGGGGAGTTCGTGCACACAGCCCGAAGCTTGGAGCGAACGACCTACGCGAACCGAGATACCTACAGCGTGAGCTATGAAAGCGCCACGCTTCCCGAAGGAAAGGCGGACAGGTATCCGGTAAGCGGCAGGGTCGGAACAGGAGAGCGCACGAGGGAGCTTCCGGGGGAAACACACCTGGTATCTTTTTATAGTCCTGTCCGGGTTTCGCCACCTCTGGCAGGCGTCGATTTTTGTGATGCTCGTCAGAGCGGAATTTATGGAAACGCCTGCGGCGCTGGCTTCCTCCGATGCTGCTTTTTGCTCACATATTCTTTCCGACTTTATCCCCCGATTCTGTGGATAACCGTATTACCGCTGCAGGTGAGCTGACACGCTCGCCGCAGTCGAACGACCGAGAGCGTAGCGAGTCAGTGAGCGAGGAAGCGGAAGAGCGCCTATGTGACATTTTCTCCTTACGCTCTGTTGTGCCGTTCGGCATCCTGTCTGAGCGTTATCTCTCTGTGCTATTTTTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTGCAGCTTCTCACACATGGCAGCCTGTTCGTCAGCATCGGGTGCGTCCAGTTTTCGAGCAGCATTCAGGCTCTGACTTTTATGAATCCCGCCATGTTGGTACGGCTTTTCTTTCTTGTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTATGATTATATCGCGTACCACTTTTCGGCTGTTTGCTGCCGTTATTCTGCGCCGCTTGGCTTTTTGACGGGCATTTCTGTCAGACAACACTGTCACTGCCAAAAAACTGCCGTGCCTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTACAATTGTTATACCGCGCATACATGCACGCTATTACAATTGCCCTGGTCAGGAGCTTTGCCCCGACACCCATGTCCAGATACGGAGCCATGTTTTGCTGACAAAACGAAGTGGAAGTAATACGCGCAGGCGGGCTATCAGTCCCCTGTTCGTCTGACGGCAGAGAGAAGACCAGGAAATCAGAAAAAGGGCTGCTGAATGCGGCAAGACCGTTTCGGTTTTTACGGGCGGCAGCTCTCGGTAAGAAAGTTAACCCACTGACTGATGATCGGGTACTGAAAGAAGTTATGAGACTGGGAGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGAGTATGCGTTTGATCGCTATTACGGGTATCACGTGCCCTGTTATCAGACTTATGGCAGATTGGCTTCCCGGAGAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCCGGGGTAAACATCTTTTTTGCAGTGTCTGCGTCAGAATCGCGTTCAGCGCGTTTCAGCAGTGCGTACAATTACAGCATTATGTTAAATTTTATAGTGTCTTTAGTCATTTGCGCTATGATTTTGTAGGTGGAGTTGCTTCATATTTTTGATATAAAGTTCTTTTCCCATCTGCTAGAGCAGTCATCGTCAGTATCAATGGTTTGTTCTTCATTGATATGCCTATTCTAGAATCTGGTCCTTATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTCATTATTTGGGTAAGCGTAATCAGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTTTTATTTTATTGAATAGATCGTCTATATATCTAAACACCTCTTTCTTACACGCGTGAGCAATAGTTGGAGTCTTCTATTGCGCCATTCTTGTTTTTCCTGGCATGATAAAGAAGATATTTTTGTGCTTCCCGTTAATGGCTATTTCATTGTGCGAGCTTGGTGATAAATGTTAAGCTCATTTAATGTTGAAATTATCTGATCTTTCCGTGTCAGAAAAACGATTCCGTCGGCATCGATGATTAAGAATATACTTTCTTTTCCATTAAAGACTCTATGCTTTTAAATGCTCTAAGGGTTTGTTTTAGTTTGTCTTTCCATTTTATTTTTTCAACATAAACATCATTAATTCCTTCTATTTCAAGTAGATTTAGGAAGTGAAAATCATCATCACCCTCAACAAAAAATGACTTTTTTATAATCATTTATTTTCTCGGTTTCATTTATCTCACCTCCCAGCCATTTTCAACTGAAAAGGAAAATCATCCATGTTAAATTGCATTGCTGTAGGTTTTGGGAATTGCTTGTCTCTTCCCAGTCTTATGTAAGATATATCTTTCTTTTTCATCTAATTCGTTTATCGCACATATTACATCATGGCTGTGTGTTGTTGTAAATATTTGATTATTATTGGTTTTGCTGCTTCTATCAAAGCGTTGATCATATCTTTGATTACTGAGTAATGAATTCCATTTTCTATCTCATCAATGAGAATAATTGAGTCTTTTTGAACTAAGATTGAGCTAATGAAAGACAGCGCTCTGCTTACTCCTTCACCAAGCATTGATATTTCATTTAATTCACTTAGTCCTATATCTAAAAAAATCTCTTTGTTTTGATCTGTTGCTATTATTGCAATATCGTTAATTCTATTATCTATTCTTTTAGGTTGCCTATTATTTCATCTTTCTTTTGTGTTAGTAGTTTGACCGTTTTTATCGTTGCTTCTTTGTTTATGCTTCTTGATGTGGTTATTACCGCGCTGCGGTTTTGAACTCATATAGCTTACACACTTTTTAGTTTGTTTTATTTCTCCGTTTATTTCTTGTGCTTTTTGTGTTATTTTTATAGTAATCAATTCTTCTGGGGGTTCTTTTCCGTTCTGTGTTTCACTAACCTTAATCGTTAAAACATTCCCCTTTTCCTGAGAATAGGGTTTGTCGCAATGGAGGGTGTTTGATAATATTGACTCAACATTGGGGACACTGGCAGTTCACTTTATTGTTTATCATCGTTGAGTATTTTGTCATTACTTCAGCCTTTCATCTCTTATTGTTATGGACATTTCTTTGGATGTGTCCATGTTATAAAAATAGCTATCCCAAAATGAGTTTTCTTTATTTAAAGAGATGCTTCATTTTCTAAAGCTTTTACTTTTAACAGAGCTGCTGGGTTTTTACGTCATAAAATGAGAAATATCGCGTCTAATATCGATGTTTTTTACCAGTTGTTTTCGGATATTACATTCAAGTGTTTTTAGTTGTTTGAAGTTATGCTCTCGAAACGCTAAAAAATTTTAAGTGGATATCTTTTATCATGTTTAAACTTGCTCCATTTCTGTTTACGTTTACATAGTAATAATGTGTTTATTTATGCATCTATGCCACTGTCTCTTTTCTAGAAGTATAATCAAAATAATATTACTTTATAGTCCTGTTTGGATTGATTTTAACAGTTTGTCGGAGTTTCTTCTTGTGATTATTGTGT -+ 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-CGTTGTACTTCGTTCAGTTACGTACTGCGCGCGCCTCTCTGTCGTCGGCAGCGTCAGATCATAGAGGCAGATGATCGGGTACGAAAGAAGTTATGAAGATGGGGAGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGATGTCGAGAGGACAGGAGTATGCGCAGAGTGCTGATCCCTTCAATACGGAGTATCCACCGTTACCCTGTTATCCGGACTTACGCCTGGCAGATTAGCTTCCCGGAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCAGGCGAAAACAGTCTGACGCATCCTTCCTGTTTTCCCGGGTAAAAACATCTCTTTTGCAGTGTCTGCGTCAGAATCGCGTTCAGCGCGTTTCAACCCGGTCGCATTACAATTACAGCATTATGCCCAAATTTTATAATTATCTTTGGTCATTTGCGCTATGATTTTTGACAGGTGGAGTTGTTTCATATTTTTGATATAAATTCTTTATCTCACTGAAGCAGTCATCGTCGAAGTATCAATGGTTTTGTTCTTCATTGATATGCCTATTCTAGAATCTGATTCCTTATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTCATTATTTGGGTAGCCGTAATCAGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTTATTTTATTGAATAGATCGTCTATATATCTAAACACCTCTTTCTTACGCGTGAGCAATGGTTAGATCTTCTGTGCGCCATTCTTGTTTTTTCTGGCATGATAAAGAAAGATATTTTGTGCTTCCGTTAATGGCTATTTCGTCATGCGAGCTTGGTGATGAAATGTTAGGCTCATTTAATGTTGAAATTATCGAATACCGTGTCAGAAAACGATTCGTCAAGCATCGATGATTAAGTATATATTTTCATTAAAAGACTCTATGCTTTTAAATGCTCTAGGGTTTGTTTTAGTTTGTCTTTCCATTTATTTTTCAACATAAACATCATTAATTCCTTCTATTTCAAGTGGTGCAAGGAGGTGAAAATCATCATCACCCTCCTTGAAATGACTTTTTATAATCATTTATTTTCTCAGTTTCATTTATCTCACCCCAGCCGAACAACTGAAAAAGAAAAATCATCCATGTTAAATTGCATTGCTGTAGGTTTTTGAGATTCTTGTCTCTTCCCAGTCTTATGTAAGAATATATCTTTCTTTTTTCATCTAATTCGTTATCCCTTTTATATTATCAGCTGTGTGTTGTTGTAAATGTTTGATTATTATTATTGGTTTTGCTGCTTCTGTCAAGCGTTGATCCTTATCTTTGATTACTGAGTAATGAATTCCATTTCTATCTCATCAATGAGAATAATTGAGTCTTTTTGAACTAAGATTGAGCTAATGAAAGATAGCGCTCTGGCACTCTTCACCAAGCATTGATGTTTCATTTAATTCCCACTTAGTCCTATATCTAAAAAATCTCTTTGTTTGATCTGTTGCTATTATTGCAATATCGTTAATTCTATTATCTATTCTTTTTAGGTTGCCTATTATTTCATCTTTTCTTTTGTGTTAGTAGTTTTGATACGTTTTTATCGTTACTTCTTTGTTTATGTTTCTTGATGTGGTTATTATCGCTGCGGTTTTTTGAATTCATATAGCTTACCTTTTTAGTTTGTTTTATTTCTCCGTTTATTTCTTGTGCTTTTTGTGTTATTTTATAGTAATCAATTCTTCTGGGAGGTTCTTTTCCGTTCTGTGTTTCACTAACCTTAATCATTAAAACATTCCCTTTCCTGAGAGCCGAGGGTTTGTCGCAATGGAGGGTGTTTGATAATACGACTCAACATTTGAGGACACGCTTGATTCACTTTATTATTATTATCTATCGTTGAGTATTTTTGTGTTACTTCCTGACCTTTCATCTCTTATTGTTTATGGACATTTCTTTGGATGTGTCCATGTTATAAAATAGCTATCCCAAAATGAGTTTTCTTTATTTAAAAGGGTGCGTTCAGCTTTTGCTTTTAACGAGCTGCTGGAGTTTTTTACGTCATAAAATGAAAATATCGCGTCTAATATCGATGTTTTCCCAAAGTTGTTTTTCGGATATTACATTAAGTGTTTTAGTTGTTTGAAGTTATGCTCTCGAAACACTTAAAATTTTTAAGTGGATATCTTTTATCATGTTTAAACTTGCTCTCCATTTCTGTTTACGTTTACATAGTATTAATAATGTGTTTATTTATGCATCACTATGCCACTGTTTCTTTTCTAGAAGTATAATCAAAATATTACTTTATAGTCCTGTTTGGATTGATTTTAACCAGTTTGTCAGGTTTCTTCTTGTGATTATTGTGTTCTGGTCGTAATCTCTAAACTGAAAACGAAAAACCACCTGGGGAGGTGGTTTGATCGAAGGTTAAGTCAGTTGGGGAACTGCTTAACCCGGGTAACTGTCTTGTGCGAGACAGAGTCACCAAACTGTCCTTTCAGTGTAGCTGTAGTCAGGCCATCACTTCAAGTACTCTCTTGAACCTCTCGCACATCGACTTTTACCAATGGCTGCTGCCAGTGGCGCTTTTGTCGTGTCTTACCGGGTTGGACTCAAGACGATAGTTACCGGATAAGGCGCAGCGGTCGGGCTGAACAGGGGTTCGTGCACACAGCCCAGCTTGGAGCGAACGACCTACACCGAACCGAGATACCTACAGCGTGAGCTATGAAAGCGCCACGCTTCCCGAAGGGAGAAGGCGGACAGGTATCCGGTAAGCAGCGGGGTCGGAACGGGAGAGCGCACGAAGAGGCTTCGGAAACACCTGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTCTGGCTTGAGCGTCGATTTTTTGTGATGCTCGTCAGGGGGCGGAGCCTGTGGAAAAACGCCTGCGGCACTATTCCTCCGGTGCTTTGCTGCTCACATATTCTTTCCGACTTTATCCCCCGATTCTGTGGATAACCATGTTACCTGTCTCTTATACACATCTCGAGCCACGAGACCAGAG 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-GGCGTTGTACTTTGATTCCAGTTACGTATTGCTGCGCGCGCACTCTCTGGTCTCGTGGGCTCAGGATGTGTATAAAGAGACAGGTTCAATCCTGACGGCGAAGAAGACCAGGAAATCAGAAAAAGGGCTGCTGAATGCGGCAAGACCGTTTCGGTTTACGGGCGGCAGCTCTCGGTAAAGAAGATTAACTCTTCGACTGGAAGTGATCGGTACTGAAAAGTTATGAGACTGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGAGGCGATGTCGGGGACAGGGGGGGTATGCGGAGTGCTGATCCTAATGCAGATATCACCAGTACGCCCTGTTAAATCAGACTTATGGCGGATCGCTTCCCGGAGAGAAAACGCTGGCGTCGAAAGGCGGACGGTGCGCTGAATTTTCCATCAGCTCGAGTGATCACCATTCGCTTTCATGCATGGCTATGCAGCGAGCTGGCAATCTGACGCATCCTTCCTGTTTTCCCGGGTGAACATCTCTTTTGCGGTGTCTGCGTCAGAATCGCGTTCAACGCGTTTCAGCAGTGCGATACAATTACAACGATATGTTAAATTTTTATAATTGTCTTTGATCATTGCTATATGATTTTTGTAGGTGGGTTGTTTCATCATTTTTAGTGTAAATTCTTTTATCTCACTGAAGCAGTCATCGTCAGTATCAATGGTTTTGTTCTTCCATTGATATACCTATTCTAGATCTGATTCCTTATTACAATAAGGTAAACTTGAACTTTGCTCTTTTCATTATTTGGGTAAGCGTAATCAGGATCTAAGGATGTAATAATAGATTCTTGTTCTTCTATTTTATTGAATAAGATCGTCTATATATCTAAACACCTCTTTCTTACACGCGTGAGCAATGGTTAAGATCTCCTATTGCCCATTCTTGTTTTCCTGGCATGATAAAGGAAAGATATTTTTATTGCTTCCGTTAAATATTTCTATTTCATTATGCAGGCTTGGTGATGAAATCATTAAGCTCATTTTTAATGTTGAAATTATCCGATCTTTCCGTGTCAGAAGAAGAAAACATTGAATTCATCGGCATCAGTGATTAAGAATATACTTTCTTTTTCGTTAAAGACTCTATGCTTTTAAATGCTCTAGGGTTTGTTTAGTTTTGTCTTCCACGTTTTTATTTTTTCAACATACGTCGTTATAGTTCATTCTGTTTTCCAGTGGTTATATGTAGAGAGTGCTATGAAATCGTCATCACCCTCAGCGAGAATGACTTTTTATGAGAAATCATGTTTTATTTTCTATATATGCTATCTCGGTTTCATTGTCTCACCTCGTCATTTTTCAGCTGTGGAAGAGTCAAGATCGTCCGTGTTAAGAGTTGCGTTGTAGCTTTCCGCCTTTGTTTCGGTTAGTTACGGGATTCTCTAAGCGCTTACGTGTCTGGCGCATTTACCCATTTAGGTCTTATTTGTTTGCGTTACGCTGC 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-CGGTATGCTTCGTCGGTTACGTATTGCTGCGCGCGCACTCTCTCTGGTCTCGTGGGCTCGGGATGTGTATAAGAGACAGGAGGTGCTGATCGCTATTACGGAGTATCCACCGTGCCCTGTTAATCAGACTTATGGCAGATTAGCTTCCCGGAGAAAAGCTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCAGAAAACGATCCTGACGCATCCTTCCTGTTTTCCCGGGGTAAAACATCTCTTTTGCGGTGCGTCTGCGTCAGAATCGCCCATTCAGCGTATCGTTCAGCGGTGCATTGAATACAGCATTATGTTAAATTTATAATTGATCTTTGATCATTACGCTATGATTTTGTAGGTGGAGTTGTTTCATATTTTGATATAAATTCTTTTATCTCACTGAAGCAGTCATCGTCAGTATCAATGGTTTTGTTCTTCATTGATAATACCTATTCTAGAATCTGATTCCTTATTACAATAAGGTAAACTTGAGCTTTTGCTTTCTTTTCATTATTTGGGTAAGCGCAATCAGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTATTTTATTGAATAGATCGTCTATATATCTAAGCACCTCTTTCTTACACGCGTGAGCAATGAAGTTAAGTCTTCTATTGCGCCATTCTTGTTTTTCCTGGCATGATAAAGAAAAGATATTTTGTGCGCTTCCGTTAATGGCTATTTCATTATGCGAGCTTGGTGATGAAATGTTAAGCTCATTTAATGTTGAAATTATCGATCTTTCCGTCAGAAAACGATTCGTCGGCATCGATGATTAAGAATATACTCTTTTCATTAAAAGACTCTATGTACCAAATGCTCTAAGGGGTTTATTTTAGTTTTGTCTTTCCATTTATTTTTCAACATAAACATCATTAATTCCTTCTATTTCAAGTAGATTACCAAAGAAGTGAAAATCATCATCACCCTCAACGAAAATGACTTTTTATAATCATTTATTTTTCTCGGTTTCATTTATCTCTCACCTCCCAGCCATTTTCAGCTGAAAAAGAAAAATCATCCATGTTAAATTGCATTGCTGTAGGTTTTGAGATTCTTGTCTCTTCCCAGTCTTATCTTAGATATATCTTTCTTTTTCATCTAATTCGTTTATCGCACATATTACATGTGGCTGTGTGTTGTTGTAAATATTTGATTATTATTGGTTTTTGCTGCTTCTATCAAAGCGTTGATCATATCTTTGATTACTGAGTAATAGATCCATTTTCTATCTCATCAATGAGAATAATTGAGTCTTTGAACTAAGATTGAGCTAATGAAAGACAGCGCTCTGCTTACTCCTTCACCAAGCATTGATATTTCATTTAATTCACTTAGTCTATATCTTAAAAAAATCTCTTTGTTTTGATCTGTTGCTATTGTGCAATATCGTTAATTCTATTATCCTATTCTTTTTAGGTTACCTATTATTTCATCTTTTCTTTTTTTGTGTTAGTAGTTTTATTACGTTTTTTTATCGTTGCTTCACTTTGTTTTATGTTTCTTGATGTGGTTATTATCGCTGCGGTTTTGAATTCATACTTAGCTTACCTTTTTAGTTTGTTTTATTTCTCCGTTTATTTCTTGTGCTTTTGTGTTATTTTTATAGTAATCAATTCTTCTGGGGGTTCTTTTTCCGTTCTGTGTTTCACTAACCTTAATCATTAAACATTCCCCTTTTCCTGAGAGCCGAGGGTTTGTCGCAATGGAGGGGTGTTTGATAATATTGACTCAACATTGAGGACACGCTTGATTCGCTTTGTGTGTTATCCTGTCTCTTATACACATCTCCGAGCCCACGAGACCAGAG 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-GTTGTACTTCGTTCCAGTTACGTATTGCTGCGCACTCTCTGGTCGTGGGCTCCGGAGTGTGTATAAGAGACAGGCCTTTGTCCGGTAATTCGAGCTTGCTGACAGGACAGGATGTACAATTGTTATACCGCGCGCAATACGCTATTACAATTGCCCTGGTCGGGGCTTTGCCCCGACACCCATGTCGAATGCTGGAGCCATGTTTTGCCAGAGCAAAACGAAGTGGAAGTAATACGCGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACGGCGAAGACCAAAATCAGAAAAGGGCTGCTGAATGCGGCAAGACCGTTCCGGTTTTTTACGGGCGGCAGCTCTCGGTAAGAAAGTTAACTCACGGCTGATGATCGAATTTGAAAGAAGTTATGAGACTGGGGGCGTTACAGAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGAGTATGCGGAGGTGCTGATCGCTATTACGGGTATCACCGTGCCCTGTTATCCAGACCTATGGCAGATTAGCTTCCCGGAGAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATGGCTATGCAGCGAGCTGAAAACGATCCTGACACATCCTTCCTGTTTTCCCGGGGTAAAACATCTCTTTTGCGGTGTCTGCGTCAGAATCGCGTTCAGCGCGTTTCAGCGGTGCGTACAATTACAGCATTATGTTAAATTTTATAATTGTCTTTAGTCATTGCGCTATGATTTTGTAGGTAGAGTTGTTTCATATTTTTTGATATAAATTCTTTTATCTCACTGAAGCGAAGTCATCGTCAGTATCAATGGTTTTGTTCTTCATTGATATGCCTATTCTAGAATCTGATTCACTTATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTCGTTATTTGGGTAAGCGTAATCAGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTTATTTTATTGAATAGATCGTCTATATATCTAAACACCTCTTTCTTACACGCGTGAGCAATGGTTAGATCTCTTCTATTCGCCATTCTTGTTTTTCCTGGCATGATAAGAAAAGATATTTTTGTGCTTCCGTTAATGGCTATTTCATTATGCGAGCTTGGTGGTGATGAAATGTTAAGCTCATTTAATGTTGGAATTATCGATCTTTCCGTGTCAGAAAACGATTCGTCAGCATCGATGATTAGAATATACTTTCTTTTCATTAAAAGACTCTATGCTTTTAAATGCTCTAAGGGTTTGTTTTAGTTTTGTCTTTCCATTGTTTTTCAACATAAACATCATTAATCCCTTCTATTTCAAGTAGATTGCAAAGGAAGTGAAAATCATCATCACCCTCAACAGAAAATGACTTTTTTATAATCATTTATTTTTCTCAGTTTCATTTATCTCCTCCCAACTAATTTTCAACTGAAAAAGAAAAATCATCCATGTTAAGTGCATTGCTGTAGGTTTTTGAGATTCCTTGTCTCTTCCCAGTCTTATGTAAGATATATCTTTTCTTTTTTCATCTAATTCGTTTATCGCACATATTACATCATGGCTGTGTGTTGTTGTAAATATTTGATTATTATTGGTTTTATGCTTCTATCAAAGCGTTGATCCTTATCTTTGATTACTGAGTAATGAATTCCATTTTCTATCTCATCAATGAGAATAATTGAGTCTTTTGAACTTCAAGATTGAGCTAATGAAAGACAGCGCTCTGCTTACTCCTTCACCAAGCATTGATATTTCATTTAATTCACTTAGTCCCTATATCTAAAAAAATCTCTTTGTTTGATCTGTTGCTATTATTGCAATATCGTTAATTCTATTATCTATTCTTTTAGGTTGCCTATTATTTCATCTTTTCTTTTGTGTTAGTAGTTTTGATACGTTTTTATCGTTGCTTCTTGTTTATGTTTCTTGATGTGATTTATTATCGCTGCGGTTTTTGAATTCATATAGCTTACCTTTTTAAGTTTTGTTTATTTCTCCGTTTATTTCTTGTGCTTTTTGTGTTATTTTTATAGTAATCAATTCTTCTGGGGGGTTCTTTTCCGTTCTGTGTTTCACTAACCTTAATCATTAAAACATTCCCCTTTTCTGGGAGCCGAGGGTTTGTCGCAATGGAGGGGTGTTTGATAATATTGACTCCAACATTGGGGACACGCTTGATTCACTTTGTGTGTTATCTATCGTTGAGTATTTTTATTGTTACTTCTGACCTTTCATCTCTTATTGTTATGGACATTTCTTTGGATGTGTCCATGTTATAAAAATAGCTATCCCAAAATGAGTTTTCTTTATTTAGAAGAGATGCTTCATTTCTAAAGCTTTTTACTTTTAACAGAGCTGCTGGGTTTTACGTCCTTAAAATGAAAATATCGCGTCTAATATCGATGTTTTCCCAAAGTTCAATTTTCCGGATATTACATTAAGTTTTTTAGTTGTTTGAGAGTTATGCTCTCGAAACATAAAATTTTAAGTGGATATCTTTATCATGTTTAAACTTGCTCTCCATTTCTGTTTACGTTTACATAGTAATAATGTGTCTATTTATGCATCACTATGCCACTGTTTCTTTTCACAAGTATAATCAAAATAATATTACTTTATAGTCCTGTTTGGATTGATTTTAACCAGTTTGTCGGAGTTTCTTCTTGTGATTATTGAGTTCTGGTCGTAATCTCCTAAACTGAAAACAGAAAAAACCACCTGGGGAGAGGTGGTTTGATCCAGAAAAGGTTAAGTCAGTTGGGGAACTGCTTAGCAGGTAACTGTCTTGGTGCGGGCAAGGTCACCAAACTGTCCTTTCAGTGTAGCTGTAGTCGACCATCACTTCAAGTACTCTCTTGAACCTCTCGCACATCGACTTTACCAATGGCTGCTGCCAGGTGGCGCTTTTGTCGTGTCTTACCGGGTTGGACTCAAGACGATAGCTGTCTCTTATACACATCTCCGAGCCACGAGACCAA 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e5531a0-6e40-43d8-87b8-3a7c8acbd3d8 -GTTGTACTTCGTTCGGTTACGTATTGCTGTACAGTCGAAGGTTAAAGTCAGTTGGGGAACTACTTAACCAGGTAACTGTCTTGTGCGAGACGAGTCACCAAAACTATTATCCTTTCAGTGTAGCTGTAGTCCAGGCCATCACTTCAAAGTACTCTCTTGAACCTCTCGCACATCGACTTTTACCAATGGCTGCTGCCAGTGGCGCTTTGTCGTGTCTTACCGGGTTGGACTCAAGACGATAGTTGCGGATAAGGCGCAGCGGTCGGGCTCGAACGGGGGAGTTCGATACACACAGCGCCAGCTTGGAGCGACGAACGACCTACACCGAACCGAGATACCTACAGCGTGAGCTATCGAAGCGCCACGCTTCCCGAAGGGAGAAAGGCGGACAAGGTATCCAGGTAAAGCGGCGAGGTCAGGAACAGGAGAGCGCACGGGGAGCTTCAGGAAACCTGGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTCTGGCTTGAGCGTCGATTTTTTGTGATGCTCGTCAGGGCGGAGCCTATGGAAAAAACGCCTGCGGCGCTGGCTTCCCTCCGGTGCTTTGCTTTTTGCTCATGTTCTTTCCGACTTTATCCCCAGGATTCTGTGGATAACCGTATTACCGCTTTTAATTGAGCTGACACCGCTCGCCGCAGTCCAGACGACGAGCGTAGCCCAGTCAGTGAAGCGAGGAAGCGGAAGAGCGCAACATTTTCTCCTTACGCTCTGTTGTGCCGTTCGGCATCCTGTCTGAGCGTTATCTCTGCTATTTTCTACTTCAAAGCGTGTCTATGATTGCTGTTCTGGAGTTCTTCGCGAGTTCGTGCACGGCTTCTCACACATGGCAGCCTGTTCGTCAGCATCAGGTGCATCCCAGTTTTCGAGCAGCGTCAGGCTCCTGACTTTTTATGAATCCGCCATTGTTAATTACGGCTTGCTGCTGCTTGTTCATCTTTCGTTTTCTCCGTTCTATCTGTCATCTGCGTTTGTGTGATTATATCGCATACCCGCTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGAAGCGCGGCGGGCATTTCTGTCGAACAACACTGTCACTGCCAAAAAACTGCCGTGCCTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGGCCTGGTGTTATACCGCGCATACATGCGCTATTACAATTGCCCTGGTCAGAACTTTGCCCCGACACCCATGTCAGATACAGAGCCATGTTTATGACAAAACTGAAATTGATAATACGCGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACGGCGAAGAAGACCAGGAAATCAGAAAAGGGCTGCTAGATGCAGCAAGACCGTTTCCGGTTTTTACGGGCGGCAGCTCTCGATAAAAGGTCACTCACTGACTGATGATCGGAGTACTGAAGAAGTTATGAGACTGGGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCAGGGACAGGAGTATGCGGAGGTGCTGATCGCTATTGCGAATTATCCACCGTGCCTGTTATCCAGACTTATGGCAGATTAGCTTCGAGGAGAGAAAACTGTGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCCTTTCATGCATAGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCCGGGTAAAACATCTCTTTTTGCAGTGTCTGCGTCAGAATCGCGTTCAGCGTGTTTCAATAAATTTTTGATACAATTACAGCATTATGTTAAATTTTATAATTGTCTTTTGATATTGCGCTATGATTGTAGGTGGAGTTGTTTCATATTTTTGATACAATTAACATCTCACTGAAGCAGTCATCGTCAGTATCAATGGTTTTGTTTTCTTCATTGATATGCCTATTCTAGAATCTGATTCCTTATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTCATTATTTGGGTAAGCGTAATCGGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTTATTTTATTGAATAGATCGTCTATATATATCTAAACACCTCTTTCTTACACGCGTGAGCAATGAGTTAGATCTTCTATTGCGCCATTCTTGTTTTCCTGGCATGATAAAGAAAGATATTTTGTGCTTCCGTTAGCGGCTATTTCATTGCGAGCTTGGTGATGAAATGTTAAAGCTCATTTAATGTTGAAATTATCGGTGCTTTCCGTGTCGAAAACGATTCCGTCGGCGCATCGATGATTAAAATATACTTTCTTTTTCATTAAAGACTCTATTCTTTTAAATGCTCTAGGGTTTGTTTTAGTTTTTGTCTTTCCATTTATTTTTTCAACATAAACATCATTAATTCCTTCTATTTCAAGTAGATTGCAAAGGAAGTGAAAATCATCCTCACCCTCAACGAAAATGACTTTTTTATAATCATTTATTTTCTCGGTTTCATTTATCTCACCTCCCAGCCATTTCAACTGAAAAGAAAAATCATCCATGTTAAATTGCATTGCTGTAGGTTTTGATTCCTTGTCTCTTCCCAGTCTTATGTAAGATATATCTTTTCTTTTTCATCTAATTCGTTTATCGCATATTACATCATGGCTGTGTGTTGTTGCTTAAATATTGATTATTATTGGTTTTGCTGCTTCTATCAAAGCGTTGATCCTTATCTTTGATTAGGTAATGAATTCCATTTTCTATCTCATCAATGAGAATAATTGAGTCTTTTGGAGCTACAGATTGAGCTAATGAAAGACAGTAACTCTGCTTACTCCCTTCTGCTTGTTGATATTTCATTTAATTCACTTAGTCCTATATCTAAAAAAATCTCTTTGTTTTGATCTGTTGCTATTATTACAATATCGTTAATTCTATTATCTATTCTTTTTAAGGTTGCCTATTATTCATCTTTTCTTTTTGTGTTAGTAGGTTTTGATGCGGTTTTTTATCGTTGCTTCTTTGTTTATGTTTCTTGATGTGGTTATTATCACTGGGTTTTTGAATTCATATAACACCTTTTTTAGTTTGTTTTATTTCTCCGTTTATTTCTTGTGCTTTTTATTGTTATTTTTATAGTAATCAATTCTTCTGGGGGTTCTTTTTCCGTTCATGTTTCACTAACCTTAATCATTAAAACACTCCCCTTTTCCTGAAGCCGAGGTTTGTCGCAATGGAGGGTGTTTGATAATATTGACTCAACATTGAGGGGACACGCTTGATTCACTTTGTGTGTTATCTATCGTTGAGTATTTTTGTATTACTTCTGACCTTTCATCCTGTCTCTTATACACATCTGACGCTGCCGACGACAGAGAGCGCGCGCAGCAATACGTAACTT 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-GTTGTACTTCGTTCAGTTACGTATTCTGCGCGCGCACTCTCTGGTCTCGTGGGCTCGGAGATGTACAGGAGACAGCTCACACATGGCAACCTGTTCGTCAGCATCAGGTGCGTCCAGTTTTCGAGCAACGTCAGAACTCTGACTTTTTGAATCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTCGTTTTCTCCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTGACGGGCATTTCTGTCAGACAACACTGTCACTGCCAAAAAACTGCCATTACCTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTGCAATTTGTTATACCGCGCATACATGCACGCTATTACAATTGCCCTGGTCAGGGCTTTGCCCGACACCCATGTCAGATACGGAGCCATGTTTTGTGACAAAACGAAGTGCATAGATGGTACGCGCAGGCGGGCTATCAGTCACGCCCTGTTCGTCTGACGGCAGAAGAAGACCAGGAAATCCAGAAAAGGACTGCTGAATGCGGCAAGACCGTTTCAGTTTTTTACGGGCAGCGGCTCTCGGTAAGAAAAGTTAACTCACTGACTGATGATCGGGTACTGAAGAGAGTTATGAGACTGGGGGCGTTACAGAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGGAGTATGCAGGAGGTGCTGATCCGCTATTACAGGTATCCACCCGTGCCTGTTACCTCAGACTTATAGCGGATTAGCTTCCCGGAGAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCGGGTAAAACATCTTTTTGCGGTGTCTGCGTCAGAATCGCGTTCAGCGCGCGTTTCAGCGGTGCGATACAATTAACACAGCATTATGTTAAATTTTATAATTGTCTTTAGTGTTGCGCTATGATTTTGTAGGTGGAGTTGTTTCATATTTTTGATATAAATTCTTTTATCTCACTGAAGCAGTCATCGTCAGTATCAATGGTTTTGTTCTTCATTGATATGCCTATTCTAGAATCTGATTCCTTATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTTCATTATTTGGGTAAGCGTAATCAGGATTACAAGGATGTAATAATAGATTCTTGTTCTTTTATTTTATTGAATAGATCGTCTATATATCTAAACACCTCTTTCTTACACGCGTGAGCAATGGTTAGATCTTCTATTGCGCCATTCTTGTTTTCCTGGCATGATAAAGAAAGATATTTCTGTGCTTCCGTTAATGGCTATTTCATTATGCGAGCTTGGTGATGAAATGTTAAGCTCATTTAATGTTGAAATTATCGATCTTTCCGTGTCAGAAAACGATTCGTCGGCATCGATGATTAAGAATATACTTTCTTTTTCATTAAAAGACTCTATGCTTTTAAATGCTCTAAGAGTTTGTTTTAGTTTTGTCTTTCCATTTATTTTTCAACATAAACATCATTAATTCCTTCTATTTCAAGTAGATTGCAAAGGAAGTGAAAATCATCATCACCCTCAACGAAAATGACTTTTTTATAATCATTTTATTTTTCTCGGTTTCATTTATCTCACCTCCCAGCCATTTCAACTGAAAGAAAAATCATCCATGTTAAATTGCATTGCTGTAGGTTTTGAGATTCCTTGTCTCTTCCCAGTCTTGTAAGATATATCTTTCTTTTTCATCTAATTCGTTTATCGCACATATTACAGCATCATGGCTGTGTGTTGTTGTAAATATTTGATTATTATTGGTTTTTTGCTACTTCTATCAAGCGTTGATCATATCTTTGATTACTGAGTAATGAATTCCATTTTCTATCATCAATGAGAATAATTGAGTCTTTTTGAACTAGATTGAGCTAATGAAAGACAGCGCTCTGCTTACTCCTTCACCAAGCATTGATATTTCATTTTAATTCACTTAATTCCTATATCCTAAAAAAATCTCTTTGTTTTGATCTGTTGCTATTATTGCAATATCGTTAATTCTATTATCTATTCTTTTTAGGTTGCCTATTATTTCATCTTTTCTTTTGTGTTAGTAGTTTGATACGTTTTTATCGTTGCTTCTTTGTTTATGTTTCTTGATGTGGTTATTATCGCTGCGGTTTTGAATTCATATAGCTTACCTTTTTAGTTTGTTTTTATTTCTCGATTTATTTCTTGTGCTTTTTTGTTATTTTTTATAGTAATCAATTCTTCTGGGGGGTTCTTTTCCGTTCTGTGTTTCACTAACCTTAATCATTAAAACATTCCCCCTTTTCCTGAGAGCCGAGGGGTTTGTCGCAATGGAGGGTGTTTGATAATATTGACTCAACATTGGGGACACGCTTGATTCACTTTGTGTGTTATCTATCGTTGAGTATTTTTGTGTTACTTCTGACCTTTCATCTCTTATTGTTATGGACATTTCTTTGGATGTGTCCATGTTATAAAAATAGCTATCCCAAAATGAGTTTTCTTTATTTAAAGAGATGCTTCATTTCTAAAGCTTTTTACTTTTAACAGAGCTGCTGGGTTTTTACGTCATAAAGTAAATATCGCGTCCTATCGATGTTTTCCCAAAGTTATTTTTTTCCGGATATTACATTAAGTGTTTTTAGTTGTTTTGAGAGATTATGCTCTCGAAACACTTAAAATTTTTAAGTGGATATCTTTTATCATGTTTAAACTTGCTCTCATTTCTGTTTACGTTTACATAGTAATAATGTGTTTATTTATGCATCACATACCACTGTTTCTTTTCGATATAATCAAAATAATATTACTTTATAGTCCTGTTGGATTGATTTTAACCAGTTTGTCGGAGTTTCTTCTTGTGATTATTGTGTTCTGGTCGTAATCTCCTAAACTGAAAACGAAAAAACCACCTGGGTGGTTTGATCGAAGGTTAAGTCAGTAAGAACTGCTTAACCAGGTAACTATCCTTGTGCGAGACGAGTCACCAAAACTGTGTCGCTTTCAGTGTAGCTGTAGTCAAATACATCCGCTGAAGTACTCTCTTGAACCTCTCGCACATCGACTTTTACCAATGGCTGCTGCCAGTGGCGCTTTGTCGTGTCTTACAGAGTTGGACTCAAGACGGTAGTTACCGGATAAGGCGCAGCGGTCGATGAACAGGGGGTTCGTGCACACAGCCCAGCTTGGAGCGAACGACCTACACCGAACCGAGATACCTACAGCGTGAGCTATGAAAGCGCCCTTTTGAGGAGAAAAAGGCGGACAGGTATCATTAGCTGTACTTGGGGTCGGACAGGAGGCGCACGAGGAGCTTCCGGAAACGCCTGAGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTCTGGCTTGAGCGATGGATTTTGTGATGCTCGCCAGAGGCGGAGCCTATGGAAAAACGCCTGCAGCGCTGGCTCCGGTGCTTTGCTTTTTTGCTCACATGTTCTTTCCGACTTTATCCCCGATTCTGTGGATAACCCATTATTACCGCTTTTTGAGTGAGCTGACACCGCTCGCCGCGGTCGAACGACCAGGCGTAGCGAGTCGGTGAGCGAGGAAGCGGAAGAGCGCCATATGTGACAGTATTTTACTCCTTACGCTCTGTTGTGCCGTTCGGCATCCTGTCCTGAGCGTTATCTCTCTGTGCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTGCAGCTTCTCACACATCTGTCTCTTATACATCTCCGAGCCGGACGAGTGCGCGCGCAGCAGTACGTAACT 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-@2553ffaa-728f-411b-9ec6-79d07c5bfd70 -GTTGTACTTCGTTCAGTTACGTATTGCTGCGCGCGCACTCTGTCGTCAGCGGCGTCAGATGTCGTATAAGAGACAGGACGCATCCTTTTTCCCGAGGTAAACATCTCTTTTTGCAGTGTCTGCGTCAGAATCGCGTTCAGCGCCGTTTCAGCGGTGCATTACAATTACATAGCATTATGTTAAATTTTATAATTGTCTTTAGTCATTGCGCTATGATTTTGTAGGTGGAGTTGTTTCATATTTTTGATATAAATTCTTTTATCTCACTGGAAGCAGTCATCGTCAGTATCAATGGTTTTGCAATTTCTTCATTGATATACCTATTCTAGAATCTGATTCCTTATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTCATTATTTGGTGTATAATCAGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTTATTTTATTGAATAGATCGTCTATGTATCTAAACACCTCTTTCTTACACGCGTGAGCAATGGTTAGATCTTCTATTGCGCCATTCTTGTTTTCCTGGCATGATAAAGAAAAGATATTTTTGTATTACTTCCGTTAATGGCTATTTCATTGCCGAGCTTGGTGATAAATGTTAAGCTCATTTAATATCGATCTTTCCGTGTCGAAAAACAAAGAATAACAATAGAAAGATCAATGTACTCGTGTGAAAGAGACATTTAATATATGAACGATCTGTTCGATAAATAATAGTGAATCTGTTTGGCAAGCAAAATGAGCATATCGGTGAATCATCTCCATAGCATAAAATTTAACATAATGCTGTGGTGTACGCACCGCTGAACGCCTTTGAACCTCACAAACGCGAACTTCCTGATGTTTTTGCAAGAAGGAAGGATGCGTCAGGATTTTCAGCTCGCTGCATAGCTATGCATGAAGAAGCGAATGGTGATCACTTT -+ -*((''((--./0*-&5?=2==8636932*-%$&%''.25**(:?2/.$:<$.A2.>59520&&$59>-./+,**+0@A@0+B33<711122:'-$+3756<@?=CB?FEKCC=1*?@>:;..A,&E=A:@<B,?<C:1@,8,$355A..),5)-=.3$$)0<898/%&%"%,,'&(;<>B@@A@RML?9DCE4NB>@QMF.1=?<?F=)>=FF<=;?JYNB;89?C?@:;=A:ACJE-'';611/-*%'&*-..4.6446<<>)<56645872+%/6?C<;545-8951:++0(.@@J?'/'(&3</:15155ABA=77DCB9=<=>;;3:3-6?AIA67</$$';:/(*.236AGBEC9:::7@>@AFA55@C?458ICC@F@5=>:&(,$#%19:5=6;;E;;;:<4;E>9;6<@AB9@596;;DE:AB=GDGA:@AIA:=;@0;:6:72;8:=.0*****'/1229:578?FC;2436)0,'345//?833846CB44@;=C?>4,18@A>;;@IGFPJ>@?OH+,0))1&)&&8=><'((('27::>:98.(%%%&&/0467'+434?6;?=8=@=8$$&$$)78<@@?,/2&&)(*3+,@A>@;??42762**58:<:@44@@?$)/F73+%$$$$#&##$%%-(&&$(('($''%%),+('$&('')($*#%$&&%%%&'&$$(($'**(1,*%%*%)260$13('(*')&.'('+-,$%''5)-,-,&')()$)'(*(,$$.856/+-#$#%##$$&#$%#&%$#$%$'#%$+,01+*)%$$&%$$-($#$+$$&./3,9;11/%%$$&$&#$&+),&*+'&'''(&$'%%&"%&(/$$'*++,-,)#(%&&&&&0*,(%+%%++*)(-3&'*6-1-0<;=43>?=20,8=:@8;?755.-%)%'%'&.2*,550**$$%** -@1195f795-0d1a-4d0c-8024-bd9aae7aa4d0 -GTTGTACTTCGTTCAGTTACGTATTGCTGCGCGCGCACTCTCTGTCGTCGGCAGCGTCAGATGTGTATAAAGAGACAGTTATGAGACTGGGGCGTTACAGAAAAACTCTTTATCGACAGCAAGCGTGTCGGGGACAGGAGTATGCGGAAGTGCTTACAGTCGCTGTGCGGAGTATCACCGTGCCCTGTTATCAGACTTAGCAGATTAAGCTTCCCGGAGAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGAGCTGAAAACGATCCTGACGCATCCTTCACCTGTTTTCCCGAGGTAAAACATCTCTTTTTGCAGTGTCTGCGTCAGAATCGCGTTCAGCGCGTTTCAGCGGTACGTACAATTACAGCATTATGTTAAATTTTATAATTGTCTTTAGTCATTGCGCTATGATTTTGTAGGTGGAGTTGTTTCATATTTTTGATATAAATTCTTTTATCTCACTGAAGCAGTCATCGTCAGTATCAATGGTTTGTTCTTCATTGATACCTATTCTAGAATCTGATTCACTTATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTCATTATTTGGGTCGCGTAATCAGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTTATTTTATTGAATAGATCTATATATCTAAACACCTCTTTCTTACGCGTGAGCAATAGTTGATCTTCTATTGCGCCATTCTTGTTTTTCCTGGCACTTGATAAAGAAAGATATTTTTGTGCTTCCGTTAATGGCTATTTCCCTATGCGAGCTTGGTGATGAAATGTTAAGCTCATTCAATGTTGAAATTATCGATCTTTCCGTGTCAGAAAACGGTCGTCAACATCGATGATTAAGAATATATACTTTCTTTTTCATTAAAAGACTCTATGCTTTTAAATGCTCTAAGGGTTTGTTTAGTTTTGTCTTTCCATTTATTTTTCAACATAAACATCATTAATTCCTTCTATTTCAAGTAGATTGCAAAGGAAATTAGAAATCATCATCACCCTCAACGAAAATGACTTTTTATATCATTTATTTTTCTCGGTTTCATTTATCTCACCTCCCAGCCATTTTCAACTGAAAAAGAAAAATCATCCATGTTAAATTGCATTGCTGTGGGTTTTGAGATTCCTTGTCTCTTCCCAGTCTTATGTAAGATATATCTTTCTTTTTTCATCTAATTCGTTTATCGCACATATTACATCATGGCTGTGTTGTCGTAAATATTTGATTATTATTGGTTTTGCTGCTTCTATCAAAGCGTTGATCGCTATCTTTGATTACTGAGTAATGAATTCCATTTTCTATCTCATCATGAGAATAATTGGAGTCTTTTTGAACTAAGATTGAGCTAATGAAAGACAGCGCTCTGCTTACTCCTTCACCAAGCATTGATATTTCCATTTAATTCACTTAGTCCTATATCTAAAAAAATCTCTTTGTTTTGATCTGTTGCTATTATTGCAATATCATTGTTCTATTATCTATTCTTTTTAGGTTGCCTATTATTTCATCTTTTCTTTTTTGTGTTAGTAGTTTTGATACGTTTTTATCGTTGCTTCTTTGTTTATGTTTCTTGATGTGGTTATTATCGCTGCGGTTTGAATTCATATAGCTTACCTTTTTAGTTTGTTTATTTCTCCGTTTATTTCTTGTGCTTTTTGTGTTATTTTTATAGTAATCAATTCTTCTGAAGTTCTTTTTCCGTTCTGTGTTTCACTAACCTTAATCATTAAAACATTCCCTTTTCCTGAGAGCCGAGGGTTTGTCGCAATGGAGGGGTGTTTGATAATATTGACTCAACATTGAGGGGGACACGCTTGATTCACTTTGTGTGTTATCTATCGTTGAGTATTTTTGTGTTACTTCTGACCTTTCATCTCTTATTGTTATGGACATTTCTTTGGATGTGTCCATGTTATAAAAATAGCTATCCCAAAATGAGTTTTCTTTATTTAAAGAGATGCTTCATTTCTAAAGCTTTTACTTTTAACAGAGCTGCGGTTTTTTACGTCATAAAATGAAAATGTCGCGTCTAATATCGATGTTTTCCCAAAGTTATTTTCCGGATATTACATTAAGTGTTTTGGTTGTTTGAGAGTTGTATATAAACATAAAATTTTTAAGTGGATATCTTTTATCATGTTTAAACTTGCTCTCCATTTCTGTTTTACGTTTTACATAGTAATAATGTGTTTATTTGCATCACTATGCCACTGTTTCTTTTCTAGAAGTATAATCAAAATAATATTACTTTATAGTCCTGTTTGGATTGATTTTAACCAGTTTGTCGGAGTTTCTTCTTGTGATTATTGTGTTCTGGTCGCTTAATCTCTAAACTGAAAACGAAAAAAAACCACCTGGGAGGGTGGTTTGATCGAAGAGTTAAGTCAGTTGGGGAACTGCTTAACCAATTGTAACTTTGTCTTGTGCAGAGACGGAGTCACCAAAACTGTCCTTTCAGTGTAGCTGTGGTGAATACATCTTCATTGCTCTCTTGAACCTCTCGCACATCGACTTTTACCAATGGCTGCTGCCAGTGGCGCTTTGTCGTGTCTTACCGGGTTGGACTCAAGACGATGGTTACCGGATAAGGCGCAGCGGGGTCGGAGCTGAACAGGGGGTTCGTGCACACAGCCCAGCTTGGAGCGAACGACCTACACCGAACCGAGATACCACAGCGTGAGCTATGAGAAAGCGCCACGCTTCCCGAGAGGAAGAAGGCGGACAGGTATCCGGTAAGCGGCAAGTCGGAACAGGAGAGCTGCTGAGGAGCTTCCGGAAACACCTGGTATCTTTATAGTCCTGTCGGGTTTCGCCACTCTGGCTTGAGCGTCGATTTTGTGATTGCTCGTCAAGGGGCCGGAGCCTATGGAAAAACGCCTGCGGCGCTGGCTTCCTCCGGTGCTTTGCTTTTGCTCACATGTTCTTTCGACTTTATCCCCCGATTCTGTGGATAACCGTATTACCGCTTTTGAGTGAGCTGACACCGCTCGCCGAGTCAGACGACCGAGCGTAGCGAGTCAGGTGAGCGAGGAAGCCCGGAAGAAACACTGCTGTGACATTTTCTCCTTGCGCTCTGTTGTGCCGTTCGGCATCCTGTCCTAAGCGTTATCTCTCTGTGCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTGCAGCTTCTCACATGGCAACCTGTTCGTCAGCATCGGGTGCGTCCAGTTTTTCGAAACAGCGTCAGGCCTGTCTCTTATACACATCTGACGCTGCCGACGACAGAGTGCGCGCGCAGCAATGCGTAAC -+ -&$)35611269G1-$49>;508346>AGE2A-614/*)+)/0;?:B>>F2;FDE@=<2(,()$$$+4:67%=9:B1)@574715D:=>:<4BEEH=@AA<7DABC@?7=?B>B@>7-$,,%(-47I=47).;:E09/=(>99%-A6;%(-64%%'+*(+'<89=':'<.3,5>60=8=;AIDA@CB;GD+'C45C<A4*/..2*22*+'56917E5;B>(,<5HIBDB;?77CG:130@B%.><45.,2,+/0112*;:.;9<=@8FC93=538CB=A:89?<;5;5</2.=::43.,,C95-&*/.-...-**33**,)+&))1733;501%33=@9:NC&-%$$$&7899>=8@ACCIFLI?4-),:.67A?C@;2&'(07@//*2,8399-21.27-&./$*4199BE@FEC<322;@89=;749:CF@=>;953***,?<=OHCD<<>245'*33<3:99>BPA:>79@A)+/6=E>DC-A+;8EFFD=<8B?DAC%BCAGHOKF=?B<@<5;35>B@><7<<:9/:%(E@:B443.3HEE6?C?ED@?CA=:/%3078:<?@A<5=;<=?AC3B0+,1?@A:?=628.)69EEH>DFF?@FDRLQI:9HIB=CBNH</EG<CCL7;>1*/-58BB;9.@=834/((//1+44?GEADAE<DGBA?HBDA;@EF@?BCSK=NG>;D:''02+50*7:957/<>A=@353--.0''(&(''+/42<>9.))295&)<@C<A==CC65111++9?OD<B>@>E?BD<?A:&&,??ABEE,?1.5EJHGDJEC;@;=?@479HE67A;A<94@>@$&+&:33361AJMJBEBA>?A?@J9:GDAAAAD;150&:<=?HE?<DKDC;6>:@=?CCE8:AL/*C44=8:84$%)'/74#$;BBA00ACCCD-.>8G>?1%&436<A<<;::CD;@C?@2(&9>@:748@>DCCBABH<<7;<9??E3?@BJAHFA:>>AKEE;<B<@35/;=@9;9NKBB>@:$$>A>A@;C>AB>A:>7;=9EBADE=FCDA??=,-4>?IG4,).6,,4/.*1B>>=;8/&759:/8C??=@GKGKEF@--=EB<3*.4<<FHD=@>A?C90='-@C9>?CA@>=<@@><:;@K1>.55**=L;C31-;;9@:0',<EFD=<7@=?BC91IJ56++748459=99:2$(=>:HA?<<=BC697:=;;>=GB89>89;?HB@>=889/EDD5?:;=>A22?NIG=@4-A0GGDF8;MJH=:B;<=>=::9:=>E@A;EAGCE5G<MLE<>@D?CA??DD@??BE>>?;CF=>KHRL9<=@>AA:63/AGH>EE>D=73-0$#(8=@KIA<5A>66.?7?ECEDAAA@A:;65:LJBAC;=B=820,%/$3'83)*)+%%8<=@C@JIE@BDAB?@;ABE777?3:;<<;.678/).-)'-=A?=AA;9<6:=@74%;==&=FEED?D@>?A&(<?DF@@KB@;898**8:=C=/?8:<FKKJGE:2=4=>=F:BBC>CB=DD6BD<@CCA9007;@331-+-$$,,56;/';?=:5>BBD<EBCB93<@CD7>=@:AA7?@PD?<A<=KF8DEMJEH>CC?;00<D<BBPDB<?7@;NDXMID=?;CD;89;?JEI5;>@9BBA@I=NKJHJAF?B49<ABE@A@AH@D-4<?B<;=G60.,95D-889B=AEDGEC>ACDIBA>2'78D=H8>=FFAHHEH;;E=D>5568875:5>D;HEUOGC4D.-+-&&+,3@CH;:--&&(+99;9JHB&6=@;?88088:A/47100,.,3AC=DEGECEJ;DDMG?@>?CHE7:EGEB;<>>:8<>EKLE7-@*333>>?A-86?BA??<837++**230)$*7(&$$6/,%,.13=@=<:8679:5D2:;:@AC,98;6B@<=@BD9:;A6.-4??:AJG>3..))11/094@CA?9:=@B?CD5ID<GH;FFDF>@A@EEDL@KB?>@CA?<<228865BB@ABGBF>5>29?@55>=EEBF?=:GHFQF<OIABDCC=>0&'&&.-(;9?>AC8;.@C83<<<<256::>=<?(?%9697)$,06=JFB;7=8=@4>140<823?98''&2$23<;=9:<;60,,>:@?E?'00=>093'&/2;;*/8>E<8=,#%36<@@8A:9=<:$);?:AA31+*,//5&)***,39<?*<896>>ESMH<?>D@BBFA:<A>?ACBE@>>CACFHCBPD<C7<A8>>BB?E22ABFA?>:<>7=65DAA6@@C8@B@B=6AA9/@>;&7?:96;?3/7>=86@@CEB>DAJA>.>,76@IJD>A<:99=D8779@14:=AB59@?>::@G@EEF.1.82**:>KD@CDDB@@?B866&*&4:9==C://0+>CDE3&,0(59@>>>/+%8%"%(4;41+:+353-4<8I?<7++CJMFFB9DC598658-1(((=<>JICD92723*,&;(58:431*=A?13?6@>:<9%%'((&2%&#)%+(($$+;'*))/&6)1%%..08'(,72;10ACDD==><&&6037@<=G=;4?9975#%(00412B<;>9/,+#%'4886;:??<;7294+()0:>CA8?=@EB><655,,?@C'28.,&&&0.96987''+;9661F>;<L?6BD89CHD@BCEDA:<CA:215%'01/;E>B@<CF=4/+120&()+82@+4$->=BAC92?321?;963@39:683;1ED><G332.1'7:**-*=>DA:49--=227<9<31B?/0/'-.3;=ECAB?81666,,(/;EFKDE=:8:<'50.**++.%3,10*=<DHA1%$$;<66D430%%/6(,,&()4=;A>D-5*46/%0003*),)<6'2@>;(+25*,/1&-0-%)5/6@DEAEDGF;<9351?02EEFG@552-$*C8BG=>=??GE@:A@<?AC6/+2)%&$%,4+'=$%5-+)%7'+%+3317;7853).1?::;</6+2:)(-,,$%(128-9(073./1A7///.3>?>E(=844>9414)3+(:;81:9:=3-+8?CFDCD>DG>?=A676@9==738.,/0-,/(/545;=CB3.6>A76A?ADF445+/.%#*8<B><1AFF@@B-2'0,*$(-7;1-0.-.0149'=?240/&-'$$%&1)(*';AAB;@@C?,7*2+-''&(+.25ID377779=1<18A@//6;;2261$&+9;@B=9<;$6?73865C>?@TG@91114'7884CBF?=;?@B@.BCEEC<:8163ACCBEBED08,,99>-*A70*8>BDACA*334:=@,.AAECD6>;=C<@G:3D,2:@=97$$;99BDJC6=.'.*4:6>;?6/;><;B@>D?DIF??960H95E5>5400/->><D7;3.-1+::3<?)?BH1/.544--',+''* -@eeef3ccf-2188-4382-8399-a9442bbbf40a -CGCTTCGTTCCGGTTACGTATTGCTGCGCGCGCCTCTCTGTCGTCGGCAGCGTCAGATGTGTATAAGAGACAGGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCCGGGGTAAAACATCTCTTTTTGCAGTGTCTGCGTCAAAATCGTTAGCGTTTCAACCCGGTGCGTACAATTACAGCATTATGTTAAATTTTATAATTGTCTTTAGTCATTGCGCTATGATTTTGTAGGTGGAGTTGTTTCATATTTTGATATAAATTCTTTTATCTCACTGAGCTTGATCATCGACAGTATCAATGGTTTCTTCATTGATATGCCTATTCTAGAATCTGATTCCTTATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTCATTATTTGGGTAAGCGTAATCAGGATCTAAGGATGTAATAATGATTCTTGTTCTTTTATTTTATTGAATAGATCGTCTATATATCGCTTCCTCTTTCTTACACGCGTGAGCAATGATTAGATCTTCTATTGCGCCATTCTTGTTTTTCCTGGCATGATAAAGAAAAGATATTTTTGTGCTTCCGTTAATGGCTATTTCATTATGCGAGCTTGGTGATGAAATGTTAAGCTCATTTAATGTTGAAATTATCGATCTTTCAGTAATAAAGGAAACGATTAAATAAGCATCAGATAAATAAAAAATATATATCATATTTAAGAGACTATTATTCTTTTTCAAATATAGTTGTTTGGTTTTGTGCTTCCATTTATTTTTCAACATAAACATCATTAATTCCTTCTATTTCAAGTAGATTGCAAAGGAAAGTGAAAATCATCATCACCCTCAACGAAAATGACTTTTTATAATCATTTGTTTTCTCAGTTTCATTTATCTCACCTCCCAGCCATTTTCAACTGAAAGAAAAATCATCCATGTTAAATTGCATTGCTGTAGGTTTTGAGATTCCTTGTCTCTTCCCAGTCTTATGTAAGATATATCTTTTCTTTTTCATCTAATTCGTTTATCGCATATTACATCATGGCTGTGTGTTGTTGTAAATATTTGATTATTATTGGTTTTGCTGCTCTATCAAAGCGTTGATCATATCTTTGATTACTGAGTAATGAATTCCATTTTCTATCTCATCAATGAGAATAATTGGTACTTTTTGAACTAAGATTGAGCTAATGAAAGACAGCGCTCTGCTTACTCCTTCACCAAACATTGATATTTCATTTGAATTCATGATCCTATATCTAAAAAAATCTCTTTGTTTGATCTGTTGCTATTATTGCAATATCGTTAATTCTATTATCTATTCTTTTTAGGTTGCTATTATTTCATCTTTTCTTTTTGTGTTAGTAGTTTTGATACGTTTTTATCGTTGCTTCTTTGTTTATGTTTCTTGATGTGGATTTATTATCGCTGCGGTTTTGAATTCATATAGCTTACCTTTTTTAGTTTTTGTTTTATTTCTCCGTTTATTTCTTGTGCTTTTGTGTTATTTTATAGTAATCAATTCTTCTGGGGGTTCTTTTTCCGTTCTGTGTTTCACTAACGTAATCATTAAAAACATTCCCCTTTTCCTGAGAGCCGAGGGTTTGTCGCAATGGAGGGGTGTTTGATAATATTGACTCAACATTTATTGAGGACACGCTTGAGGATTCACTTTTATTGTGTTATCTATCGTTGAGTATTTTTGTGACACTTCTGACCTTTCATCTCTTATTGTTATGGACATTTCTTTGGATGTGTCCATGTTATAAAAATAGCTATCCCAAAATGAGTTTTCTTTATTTAAAGAGATGCTTCATTTCTAAAACTTTTACTTTTAACAGAGCTGCTGGGTTTTACGTCATAAAATGAAAATGTCGCGTCTAATATCGATGTTTTCCCAAAGTTGTTTTTCCGGATATTACATTAAGTGTTTTTAGTTGTTTGAGAGTTATGCTCTCGAAACACTTAAAATTTTTAAGTGGATATCTTTTATCATGTTCTTTTGTTTCCTCCCATTTCTGTTTACGTTTACATAGTAATAATGTGTTTATTTATGCATCACTATGCCACTGTTTCTTTTCTAGAGTATAATCAAAATAATATTACTTTATAGTCCTGTTTGGATTGATTTTAACCAGTTTGTCGGAGTTTCTTCTTGCTGATTATTGTGTTCTGGTCGTAATCTCTAAACTGAAAACGAAAAAACCACCTGGGGAGGGTGGTTTGATCGAAGTTAAGTCAGTTGGAGAACTGTAACCAGGTAACTGTCTTGTGCCAGGACGAGTCACCAAAACTGTCCTTTCAGTGTAGCTGTAGTCAGGCCATCGCTAAGTACTCTCTTGAACCTCTCACGCACATCGACTTTTACCAATGGCTGCTGCCAGTGGCGCTTTGTCGTGTCTTACCGGGTTGGACTCAGAGACGATAGTTACCGGATAAGGCGCAGCGGTCGGGCTGAACAGGGGGTTCGTGCACAGCCCAGCTTAAGAGCGAACGACCTACACCGAACCGAGATACCTACAGCGTGAGCTATGAAGCGCCACGCTTCCCGAAGGAGAAAGGCGGACGGGTATCCGGTAAGCGGCGCAGGGTCGGAACAGGAGAGCGCACCAGGGGAGCTTCCGGAAACACCTGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTCTGAAACTTGAGCGTCGATTTTGTGATGCTCGTCAGGGGGCGGAGCCTATGGAAAAACGCCTGCGGCGCTGGCTTCCTCCGGTGCTTTGCTTTTTGCTCACGTATTTCTTTCCGACTTTATCCCCCGATTCTTCAGCGGATAACCGTATTACCGCTTTTGAGTGAGCTGACTTGCCGCTCGCCGCAGTCAGACGACCGAGCGTAGCGAGTCAGTGAGCGAGGGAAGCGGAAGAGAGCGCCTTATGTGACATTTTCTCCTTACGCTCTGTTGTGCCGTTCGGCATCCTGTCCTGAGCGTTATCTCTCTATTATATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTGCAGCTTCCACACATGGCAGCCTGTTCGTCAGCGCATCGGGTGCGTCAGTTTTCGAGCAGCGTCAGGCTCCTGACTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTGACGGGCATTTCTGTCGAACAACACTGTCACTGCCAAAAAACTGCCGTGCCTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTGCAGATTGTTATACCGCGCATACACATGCGCTATTACAATTGCCCTGGTCAAGAGGCTTTGCCCCGACACCCATGTCAGATACGGAGCCATGTTTTATGACAAAACGAAGTGGAAGTAATACGCGCAGGCAGGCTATCAGTCGCCCTGTTCGTCTGACGGCAGAAGACCAGGAAATCAGAAAAGGGCTGCTGAATGCGGCAAGACCGTTTCCGGTTTTACGGGCGGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCGGGTACTGAAAGAAGTTATGAGACTGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGAACTAGGGGAGTATGCGGAGGTGCTGATCGCTATTACGGAGTATCACCGATACCCTGTTATCCAGACTTATAGCAGATTAGCTTCCCGGAGAAAACTGTCCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAAACAGTCTGACGCATCCTTCCTGTTTTCCCGGGGTAACTCTCTTTTGCGGTGTCTGCGTCAGAATCGCGTTCAGCGCGTTTCAACGGTGCGTACAATTACAGCATTATATTTAAATTTATAATTGTCTTTAGTCATTTGCGCTATGATTTTGTAGGTGGAGTTGTTTCATATTGCGGTACTTTGATTCTTTTTATCTCACTGAAGCAGTCATCGTCAGTATCAATGGTTTGTTCTTCATCTGTCTCTTATACACATCTGACACAACGACGACAGAGAGTGCGCGCGCAACAATACGTAAC 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-CGGTAGCCTTCGTTCGGTTACGTATTGCTGCGCGCACTCTCTGAGTCTCGTGGGCTCGGAGATGTGTATAAGAGACAGGTGCTATTTTCTACTTCAAAGCGTGTCCTGGATGCTGTTCTGGAGTTCGTTCTGCGAGAGTTCGTGCAGCTTCTCACACATGGCAGCCTGTTCGTCAGCATCAGGTGCGTCCAGTTTTTCGAGCAGCGTCGGGCTCTGACTTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTTGTTCATCTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTTGTGTGATTATATCGCGTACCACTTTTCGACTGTTTGCTGCCCGTTATTCTGCCGCTTTGGCTTTCTGACAGGCATTTGTCAGACAACACTGTCACTGCCAAAAACTGCCGTGCCTTTATCCCGGTAATTCGAGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCATACATGCACGCTATTACAATTGCCCTGGTCAGGGCTTTGCCCCATGACTTACCCATGTCAGATACGGAGCCATGTTTTATGACAAAACGAAGTGGAAGTAATACGCGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACAGCAGAGAAGAAGACCGGGAAATCAGAAGAACTGCTGAATGCAGCAGAGACCGTTCCGGTTTACGGGCGGCAGCTCTCGGTAAAGTTAACTCACTGACTGATGATCGGGTACTGAAAGAAGTTATGAGACTGGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGAGTATACGCGGAGGTGCTGATCGCTATTACAGGTATCACCGTACCTATTATCAGACTTATAGCAGATTAGCTTCCCGGAGAAAACTGTCAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAACGATCCTGGCCGCATCCTTCCTGTTTTCGAGGTAAAACATCTCTTTTTGCAGTGTCTGCGTCAGAATCGCGTTCAGCGCGTTTCAGCGGTGCGTACAATTACAGCATTATGTTAAATTTTATAATTGTCTTTAGTCATTGCGCTATGATTTTGTAGGTGGAGTTGTTTCATATTTTGATATAAATTCTTTTATCTCACTGAAGCAGTCATCGTCAGTATCAATGGTTTGTTCTTCATTGATATGCCTATTCTAGAATCTGATTCCTTATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTCATTATTTGGGTAAGCGTAATCAGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTTATTTTATTGAATAGATCGTCTATATATCTAAACACCTCTTTCTTACACGCGTGAGCAATGGTTAAGATCTTCTATTGCGCCATTCTTGTTTTCTGGCATGATAAAGAAAGATATTTTGTACTTCCGTTAATGGCTATTTCATTATGCGAGCTTGGTGAGTAAATGTTAAGCTCATTTAATGTTGAAATTATCGATCTTTCCGTGTCGAAAACGATTCGTCGGCATCGATGATTAGAATATACTTTCTTTTTCATTAAAAGACTCTATACTTTTAAATGCCTCTAAGGGAGTTTTGTTTAGTTTTGTCTTTCCATTTTATTTTTCAACATAAACATCATTAATTCCTTCTATTTCCAAGTAGATTGCAGGAAGTGAAAATCATCATCACCCTCAACGAAAATGGCTTTTTATAATCATTTATTTTTCTCGGTTTCATTGTCTACCTCCCAGCCATTTTCAACTGAAAAGAAAATCATCCATGTTAAATTGCATTGCTGTAGGTTTTTGAGATTCCTTGTCTCTTCCCAGTCTTATGTAAGATATATCTTTTCTTTTTTCATCTAATTCGTTTATCGCACATATTACATCATGGCTGTGTGTTGTTGTAAATATTTGATTGGCTATTGGTTTTGCTGCTTTAATAAAGCGTTGATCATATCTTTGATTACTGAGTAATGAATTCCATTTCTATCTCATCAATGAGAATAATTGAGTCTTTTGAACTAAGATTGAGCTAATGAAAAGACATCTGCCTCCTTCACAAGCATTGATATTTCATTTAATTCACTTAGTCCTATATCTAAAAAATCTCTTTGTTTTGATCTGTTGCTATTATTGCAATATCAGTTAATTCTATTATCTATTCTTTTTAGGTTGCCTATTATTTCATCTTTTCTTTTTTTTGTGTTAGTAGTTTTGGTGTTTTTTGTCGTTGCTTCTTTGTTTATGTTTCTTGATGTGGTTGTATCGCTGCGGTTTTGAGATTCATATAACACAACTTTTTTAGTTTGTTTTATTTCTCAGTTTATTTCTTGTGCTTTTGTATTATTGTTTTATAGTAATCATCAGCTTTAGGGGGTTCTTTCCGTTCTGTGTTTCTACGCTAGCAACGCTTAATCATTAAAACATTCCCGCTTTTCCACCTGAAACCGAGGGTTTGTCGCAATGGAGGGTGTTTGATAATATTGACTCAACATTGGGGACACGCTTGATTCACTTTGTGTGTTATCTATCGTTGAGTATTTTTGTGTTACTTCTGACCTTTCATCTCTTATTGTTATGGACATTCCTTTGGATGTGTCCATGTTATAAAAATAGCTATCCCAAAATGAGTTTTTCTTTATTTAAAGAAGATGCTTCATTTCTAAAGCTTTTTACTTTTAACGCAGAGCTGCTGGGTTTTACGTCATAAAATGAAAATATCGCGTCTAATATCATGTTTTCCCAAGGAGTTGTTTTTCCGGATATTACATTAAGTGTTTTAGTTGTTTGAGAGTTATGCTCTCTCGAAACATAAAATTTTAAGTGGATATCTTTATCAATAATTAACTTACTCTCATTTCTGTTTACGTTTACATAGTGCTCAACAACACCTTTAGCATGCATCACTATACCACTGTTTCTTTTCTAGAAGTATGATCAAAATATGTGCTTTACATAGTCCTGTTTGGATTGATTTAACCAGTTTGTCGGAGTCTTCTTGTGATTATTATTGTATTCTGTGGTCGTAATCTCCCTAGAAACTGAAAACAGAGAACTACACCTGCAGGCTCTGTGGTTGATCGAGAAAAGGATGCAGGCTGCAAGTCAGTACT 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d6bdcab-ef5c-4ff8-a928-23066fb4e887 -GATGTGCTTCGTTCAGTTACGTATTGCTGCGCGCACTCTCTGGTCTCTGGGCTCGGAGATGTGTGTATAGAGACGCTGTTATCAGACTTATGGCAGATTAGCTTCCCGGAGAAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAAGTGATCACCATTCATCATGCATAGCTATGCGGGCAGACTGCGAAAACGATCCTGACTCCTTCCTGTTTTCCGGGGTAAAACATCTCTTTTTGCGGTGTCTGCGTCAGAAATTCAGCGCGTTTCAGCGGTGCGTACAATTACAGCATTATGTTAAATTTTGTATTGTCTTTGTAGTCATTTACTTCTATGATTTTGTAGGTGGAGTTGTTTCATATTTTGATATAAATTCTTTTATCTCACTGAAGCAGTCATCGTCAGTATCAATGGTTTTGTTCTTCATTGATATGCCTATTCAGAATCTGATTCCTTATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTTCATTATTTGGGTAAGCGTAATCCAGGATCTAGAATAGGCATATCAGTGAAAAAGGCGCTCCTGACCAGTGAAGAGGCCATATCTGACCTATTCTGCTGCCATCAGCAAT -+ -$$%%%&013/7>4+'.386@D8338>?HB2;15%%0+2(91<>;>8:-*,--.2&*'--<4/4'2-.,4&%%*,&12551)$>,,/,,,AE??>==?6/.'''-8>B03<+,,-=CA@<A@<A98=<17581:*0<BC66@AA<>;;/09:6470999-%171+98==8<;6#'36;AC;7:689<<89%*./(&$++$-+--<-;=>55:4;*%&%*%/454@CAHA/318?G?4599=9?DEA@?EA@5?(0@B>CE?<3.,%&%$%%+95?2.49;?=416:55?4-18<>CDBF<0?-;--2;>ABC998:=;&$.)-/:89=:=$$)(18022*%%(0'867%%A9555317::8;-0586??,7.;A;=GE@>?<948>?@>EBA<<=?>./546/A7=7B;9<A648;&*E+&>@</>=DENF;C@=79;::<;:91/.,(,%%(#025<370=<=7/503=<>9<+,2:89<358;9FJD@CCCJB?=66:=</68KC@;;;7-.07-021%&(5:<99%%4.99;566;9517((44+(()-&*''$$$$#++)166(,'('#$&'/%$$)$&*()$+(+5**%#%$&$&#&$$*(%')(%$#&$%# -@ba3e1438-5606-4371-aab8-b41abb82649a -TTGCGGTGTCTGCGTCAGAATCGCGTTCAGCGCGTTTCAGCAGTGCGTACAATTACAACATTGTAAATTTTATAATTGTCTTTAGTCATTGCGCTATATTGATTTTGTAGGAACGGAGTTGTTTCATATTTTTGATATAAATTCTTTTCTCACTGAAACAGTCATCGTCAGTATCAATGGTTTTGTTCTTCATTAATACTGTTATCACAGAATCTGATTCCTTAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTCATTATTTGGGTAAGCGTAATCAGGATCTAAGGATACAATAATAGATTCTTGTTCTTTTATTTATTGAATAGATCGTCTATATATCTAAACACCTCTTTCTTACACGTGAGCAATGAAGTTAGATCTTCTATTGCGCCATTCTTGTTTTTCCTGGCATGATAAAGAAAAGATATTTTGTGCTTCCGTTAATGGCTATTTCATTATGCGAGCTTGGTACGTGAAATGTTAAGCTCATTTAATGTTGAAATTATCGATCTTTCCGTGTCAGAAAACGATTCGTCGGCATCGATGATTAAAAATATACTTTCTTTTTCATTAAAAGACTCTATGCTTTTAAATACTCTAAGGGTTTGTTTAGTTTTGTCTTTCCATTTTATTTTTTCAACACTAAGCTTATCCATTAATTCCTTCCTATTTCAAGTAGATTGCAAAGGAAGTGAAAATCATCATCACCCTCAACGAAAATGACTTTTTATAATCATTTATTTTCTCGGTTTCATTTATCACCTCCAGCCATTTTCAACTGAAAAAGAAAAATCATCCATGTTAAATTGCATTGCTGTGAGTTTTTGAGATTCCTTGTCTCTTCCCAGTCTTATGTAAGATATATCTTTCTTTTTCATCTAATTCGTTTATCGCACATATTACATCATGGCTGTCTGTTGTTGTAAATATTTGATTATTATTGGTTTTTGCTGCTTCTATCAAAGCGTTGATCATATCTTTGATTACCGGAAGTAATGAATTCATTTTCTATCTCATCAATGAGAATAATTGAGTCTTTTTGAACTAAGATTGAGCTAATGAAAGACAGCGCTCTTCCTTTACTCCTTCACCAAACATTGATATTTCATTTAATTCACTTAGTCCTATATCTAAAAAAATCTTTCTTTGTTTTGATCTGTTGTTGCTATTATTGCAATATCGTTAATTCTATTATCTATTCTTTTAGGTTGCCTATTATTTCATCTTTTCTTTTGTGTTAGTAGTTTGTTACGTTTATCGTTGCTTCTTTGTTTATGTTTCTTGATGTGGTTATTATCGCTGCGGTTTGAATTCACTATAAGCTTACCTTTTTTAGTTTGTTTTATTTCTCCGTTTATTTCTTGTGCTTTTTGTGTTATTTTATAGTAATCAATTCTTCAGGGGGTTCTTTTCCGTTCTGTGTTTCACTAACC 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-GTTATTACTTCGTTCCGGTTACGTATTGCTGCGCGCGCACTCTCATCGTCAGCAGCGTCAGATGTGTATAAGAGAGACAGTTCAGGGGAAACACCTGGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTCTGGCTTGAGCGTCGATTTTTGTGATGCTGCTCGTCGGGGGCGGAGCCTATGGGCGCCTGCGGCGCTGGCCCTCGGTGCTTTGCTTTTTTGCTCACATGTTCTTTCCGACTTTATCCCCCGATTCTGTGGATAACCGTATTAAGCTTTTGAGTGAGCTGACACCGCTCGCACCGGTCGAACGACCGAGCGTAGCGAGTCAGTGAGGAAGCGGAAGAGCGCCTTATGTGACATTTCTCCTTACGCTCTGTTGTGCCGTTCGGCATCCTGTCCTGAGCGTTATCTCTCTGTGCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTGCAGCTTCTCACACATGGCAACCTGTTCGTCAGCATCGGGTGCGTCAGTTTTTCCGAGCAGCGTCAGGCTCTGACTTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTTCGTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTTGACGGGCATTTCTGTCAGACAACACTGTCACTGCCAAAAAACTGCCGTGCCTTTGTCCGGTAATTCAGGCTTGCTGACAGGACAGGATGTACGAATTGTTATACCGCGCATACATGCACGCTATTACAATTTGCCTGGTCAGGCTTTGCCCCGACGCCTTACATGTCAGATACGGGCCATGTTTTATGACAAAACGAAGTGGAGTAATACGCGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACGGCAGAAGACCAGGAAATCAGAAAAAGGGCTGAATGCGGCAGACCGTTTCCGGTTTTTTACGGGCGGCAGCTCTCGGTAAGAGAAGTTAACTCACTGACTGATGATCGGGTACTGAAAGAAGTTATGAGACTGGGGCGTTACAGAAAAACTCTTTATCGACGGCAAACGTGTCGGGGACAGGGAGTATGCGGAGGTGCTGATCGCTATTACGGAGTATCACCGTGCCTGTTATCAGACTTATGGCAGATTAGCTTCCGGAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAACGATCTGACGCATCCCTTCCTGTTTTCCGGGGTAAAACATCTCTTTTTGCGGTGTACTGCGTCAGAATCGCGCTCAGCGCGTTTCAGCGGTGCGTACAATTACAGCGATATGTTAAATTTTATAATTGTCTTTAGTCATTTGCGCTATGATTTTGTAGGTGGAGTTGTTTCATATTTTTGATATAAATTCTTTTTATCTCACTGAAGCAGTCATCGTCAGTATCAATGGTTTGTTCTTCATTGATATGCCTATTCCTAAGAATCTGATTCATATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTTTCATTATTTGGGTAAGCGTAATCAGGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTTATTTTTATTGAATAGATCGTCTATATATCTAAACACCTCTTTCTTACACGCGTGAGCAATGATTGGGAATCTTCTATTGCGCCATTCTTGTTCCTGGCATGATAAAGAAAGATATTTTTGTTTCCGTTAATGGCTATTGTTATGCGAGCTTAGTGATGGAAATGTTAAGCTCATTTAATGTTGAAATTATCGATCTTTCCGTGTCAGAAAACGATTCGTCGGCATCGATGATTAAGAATATACTTTCTTTTTCATTAAAAGACTCTATGCTTTTAAATGCTCTAAGGGTTTGTTTTAGTTTTGTCTTTCCATTTATTTTTTCAACATAAACATCATTAATTCCTTCTATTTCAAGTAGATTGCAAAGGAAGTGAAATCATCATCACCCTCAACGAAAATGACTTTTTTATAATCATTTATTTTCTCGGTTTCATTTATCTCACCTCCAGCCATTTCAACTGAAAAAGAAAAATCATCCATGTTAAATTGCATTGCTGCTTTTTGAGATTCCTTGTCTCTTCCCAGTCTTATGTAAGATATATCTTTTCTTTTTTCATCTAATTCGTTTATCGCACATATTACATCATGGCTGTGTGTTGTTGTAAATATTTGATTATTATTGGTTTTGCTGCTTCTATCAAAGCGTTGATCATATCTTTGATTACTGAGTAATGAATTCATTTTCTATCTCATCAATGAGAATAATTGAGTCTTTTTGAACTAAGATTGAGCTAATGAAAGACAGCGCTTCTCTGCTTACTCCTTCACCAAACATTGATATTTCATTTAATTCACTTAGTCCTATATCTAAAAAAATCTCTTTGTTTTGATCTGTTGCTATTATTGCAATATCATTAATTCTATTATCTATTCTTTTAGGTTGCCTATTATTTCATCTTTTTCTTTTTTGTGTTAGTAGTTTTTGATACGTTTTTATCGTTGCTTCTTTGTTTATGTTTCTTGATGTGGTTATTATCGCTGCGGTTTGAATTCATATAGCTTACCTTTTTTAGTTTGTTTTATTTCTCCGTTTATTTCTTGTGCTTTTTGTGTTATTTTATAGTAATCAATTCTTCTGGAGGTTCTTTTTCCGTTCTGTGTTTCACTAACCTTAATCATTAAAACATTCCCCTTTTCCTGAGAGCCGAGGGGTTTGTCATAAATGGAGGGTGTTTGATAATATTGACTCAACATTGAGGACACGCTTGATTCACTTTGTGTGTTATCTATCGTTGAGTATTTTTGTGTTACTTCTGACCTTTCATCTCTTATTGTTATGGACATTTCTTTGGATGTGTCCATGTTATAAAAATAGCTATCCCAAAATGAGTTTCTTTATTTAAAAGAGATGCTTCATTTCTAAAGCTTTTTACTTTTAACAGAGCTGCTGGGTTTTTACGTCATAAAATGAAAATATCGCGTCTAATATCGATGTTTTCCCAAAGTTGTTTTTCGGATATTACATTAAGTGTTTTTAGTTGTTGAGAGTTATGCTCTCGAAACACTTAAAATTTTAAGTGGATATCTTTTATCGTAATGTTTAAACTTACTCCATTCTGTTTACGTTTACATAGTAATAATGTGTTTATTTATGCATCACTATGCCACTGTTTCTTTTCTAGAAGTATAATCAAAATAATATTACTTTATAGTCCTGTTTGGATTGATTTTAGCTCCAGTTTGTCGGAGTTTCTTCTTGTGATTATTGTGTTCTGGTCGTAATCTCCTAAACTGAAAACAGAAAAAACCACCTGGGGAGGTGGTTTGATCGAAGGTTAAGTCAGTTGGGGAACTGCTTAGCAGGTAACTGTCTTGTGCGAGACGAGTCACCAAAACTGTCCTTTCAGTGTAGCTGCTTAGTCAGGCCATCACTTCAAGTACTCTCTTGAACCTCTCGCATCGACTTTTACCAATGGCTGCTGCCAGTGGCGCTTTGTCGTGTCTTACCGGGTTGGACTCAAGACGATAGTTACCGGATAAGGCGCAGCGGTCCGGGCTGAACGGGGGGTTCGTGCACACAGCCAGCTTGGAGCAGCCGGCCTACACCGAACTCGAAGGTCTACAGCGTGAGCTATGAAAGCGCCACGCTTCCCGAAGGAGAAAGGCGGACAGGTATCCGAGGCGGTAAGCGGCGGGGTCGGAACAGGAGAGCGCACGAGGGGGCTTCAGGGCTGTCTCTTATACATCTCCGAGCCCACGGGGCCAGAAGACCTGCGCGCATAACCGAATACTTGCGGCCAAC 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-TGTTGCTGATTCGGTACGTATTGCTGCGCACTTTTCCTCTCTGTCGGCAGCGTCAGATCTATAAGAGACAGCGCTGTGGGTATCTCGGTTCGGTGTAGGTCGTTCGCTCCAGCCTGGGCTGTGCGAACCCCCGTTCAGCAAACCGCTGCACTTATCCGGTAACTATCGTCTTGATTAACCCGGTAAGGTACGACGCCAGCGCCACTGGCAGCAGTATTGGTAAAGTCGAATGTGCGAGGGGTTCAAAGTACCCGAAGTGATAGCCCACAATACAATACACTGAAAGGACAGTTTTGGTGACTCGTCTCGCTACGAATTGATTACCTGAATTGGCGCAGTTCCCAACTGACGACTTAACCTTCGATCAAGCTCCCACCCCTCCCCCAGGTGGTTTTCGTTTTCAGTTTAGGAGATTACGACAGAACAATAATCTAAGAAAACTCGACAAACTGGTTAAAAATCAATCAACAGGACTATAAAGTAATATTATTTTGATTTTCACTTCTAGAAAAGGAACACAGTGGCATAGTGATGCGTAGAAATAAACACATTATTACTATAAACGTAAATGAAATGGAGAGCAAGTTTAAACATGATAAAAGATATATCCACTTAAAAAATTTTAGAATTTTTCCGAAACTTTTATAACTCTCAATCAACTTCTAAAAACACTTAATGTAATATCCGGAAAAAACTGCTCTGAAGGACATCGATATTAGACGCGATATTTTCATTTTATGACGTAAAAACCCAGCAGCTCTGTTAAAAGTAAAGCTTTAGAAATGAAGCATCTCTTTAAATAAAGAAAACTCATTTGGGATAGCTATTTTTTATAACATGGACACATCAAAAGAAATGTCCATAACAATAGAGATGAAAGGTCAAGTAACACAAAAATGTAACGATATAGATAACACACAAAGTGAATCAAGCGTGTCCCTCAATGTTGAGTCAATATTATCAAACACCTCATTGCGACAAACCCTCGACTCTCAGGAAAAGAGAGTGCAATGATTAAGGTTAGTGAAACACAAGAACGGAAAAGAACCCCCAGAAGAATTGATTACTATAAAAATAACACAAAAAGCACAAAGAAATAAACGGAGAAATAAAACAAACTAAAAAGGTAAGCTATGAATTCAAAGCCGCAGCGATAATAACCACATCAAACATAAACAAGAAGCAGCTTGAATAAAAAGCAGTAATAAACTAACACAAAGAAAGATGAAATAATAGGCAACCTAAAAAGAATAGATAATAGAATTAACGATATTGCAATAATAGCAACAGATCAAAACAAAGAGATTTTTTAGATATGGGTTAAGTGGAATTAAATGAAATATCAATGCTTGGTGAAGGAGTAAGCAGAGCGCTGTCTTTCATTAGCTCAATCTCTTAGTTCAAAAAAAGACTTCAATTATTCTCGTAATTAGATAGAAATGTGGAATTATTACTCAGTAATCAAAGATATATGATCAACGCTTTGATGAAGCAGCAAAAACCAATAATAATCAAATATTTACAACAACACATATGATGTAATATGTGCAGAATAAACGAATTAGATGAAAAAAGAAAAGATATATCTTACATGGGAAGGGGCAGAATCTCAACCTACCTTAGTAAATTTATGGATGATTTTTTCTTTTTCAGTTGAAAATGGCTGGGGAGGGTGAGATAAATGAAACCGAAAAATAAATGATTATAAAAAAGTCATTTTCGTTGAGGGTGATGATGATTTTCCTTTACGTCTACTTGAAATAGAAGGAATTAATGATGTTTATGTTGAAAAAATAAATGGAAGAACAAAGCGAAAACAAACCCTTAGAGCATTTAAAAGCTTTGAGTCTTTTAATGAAAAAGAAAGTATATTCTTAATCATCGTCTAGACAGAATCGTTTTCTGACACGGAAAAGATCGATAATTCAACATTAAATGAGCTTAACATTTCATCATAAACTCATATAATGAAATAGCCATTAACGGAAGCACAAAAAATATCTTTCTTTATCATACGGAAAAAACAAGAATGGCGCAATAGAAGATCTAATCATTGCTCACGATATCAAGAAAGAGGTGTTTAGATATATAGACGATCTATTCAATAAAATAAAGAACAAGAATCTGTATTACATCGACAGATCCTGATTACGCTTGCAAATAATCGGAAAGAAAGCAAAAGTTCAGGTTTGGTTTGTAATAAGGAGTCAGATCGAATAGGCATATCAATGAAGAACAAAACCATTGATACTGACGATGACTACTTCAGTGAGATAAAAGAATTTATATCAAAAGTATGAAACAACTCCACCTACAAATCATAGCGCAATGACTAAAGACAATTATAAAATTTAACATAATGCGTAATTAGCGCACCGCTGGCTTGCGCTGAACGCGATTCTGACGCGAACACCGCAAAAGAAGTGTTTTACCCGGGAAAACAGGGAAGGATCACGTCAGGATCGTTTTCAGCTCGCTACGCATAGCTATGCAACAAGCAATGGTGATCACTTTGGGAGCTTACAGTGTTCGTCTGTTTTCGACAGTTTTCTCTCCGAGGAGCTAATCACCGCGTCTGGATAAACAGGGCACGGTGATACTCCGTAATAGCGATCTTTCTTTTTCCTGTACAACACGCTTGCCGTCGATAAAGAGTTTTTCTGCTTAACGCCCCAGTCTCATAACTTCTTTCAGTACCCGATCATCAGTCAGTGGAGTTAACTTTCTTACCGAAGAGCTGCCGCCCGTAAAAACGGAAACGGTCTTGCCGCATTCAGCAACCCCTTTTCTGATTTTCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCAACTGATAACCGCCTGCGTATTACTTCCACTTCGTTTGTCGCAAAACATGGCTCGTATCTGACACTTGCTTGTAGGTGTCAGGGCAAAGAAACCCCTGACCAGAACGAATGTAATAGCGTGTGTGCGCGTTGCCATAGCCGCACATCTAATCAGCAAACTCGATACCGACAAAGAGCACGGCGGATTTTGGCGGTGACAGTGTTGTCTGACAAATACCGTCAAAAAGCCAAGCGGCAAACAACGGCTTATCCGCCGGTCGAAAAGTGGTACGCGGTGATATATAATGCACAACACGAGATGACAGACAAGACGGAGAAAGCGAAAAAGATGAACAAGCAACGGCAAATGACGCTCAACATGGCAGGGTTCGCAAGAGATCAGAGCCTGACGCTGCTCGAAAAACTGGACGCACCGGTGACGAACAGGCTTTGTTGTGTGGAAGCTTCACTTTTTTGAACTCATGAAGAACTCAGAACAGCATCAGACACGCGCTTTGATAGAAAAAATAGCACAGAGAGATAACGCTCAGGACAGGATGCCGAACAGCTAACCAGACGTAAGGAGAAAATGTCTGCAAGGCATCTTCGCCTCAGCTCACTGACTCGCTACGCTCGGTCGTTCGACTGCGGCGAGCGGTGTCGAAAACACTCAAAGCGGTAATACGGTTTATCCACAAATCCGGGGGATAAAGTCGAGGAAGAACATGTGAGCAAAAAACCAAGCACCGGAGAAAGCCAACGCGGGCGTTTTCCCATAGGCTCCGCCCCCTGACGAGCATCACAAAAATCGACGCTCAAGCCCAGAAATTTGGCGAAACCCGACTGGGACTATAAAATGCAGGTGTTTCCCCTGGAAGCTCCCTCCGCTCTCCTGTTTCCGACCCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGCGTAGGCTGTCTTATACACATCTGACGCTACCGACGACAGGGGGTGCGCGCGCAACAATACAAA -+ -$,$%$$&%$.,2#%730*-&&'/.2/4,2&''(((&))&-7',7*)+0,1.9;8.0%44-28)*-*(??@:=.,23*',7?3,*$95:D,>1:;:0(5@=BCE@B78=$)&&.&.96?21'&%,(&*67988@D=1)2?69::;77FA>3456@;=D)/956<??:A::=0*%&#%**':9%*.%'(&#%))&#$%&(&621>88813'%+,&##%)-*00*+'%))%$((&,/--%'=ABGD@01%%*))0)$%$38*(%$42*)&)$&%%&#$%)+**%((6%/:./'5;<<7%)2-/0>:42;29'*/&&$$$%&&$4<4;;29$&&-(,))((+05*,+$%)')&#&$/009:<>?>686/7&'%,,%-)*,56(.::73(&0.:9<BAF7204;9797;CE711./,,'(&,/,+1))).3307/(<%$'$/30*3)77?:CC39;9<A?;9<A>7?>604/-+*54<<BF@9;35;>CBCA91346/+',+(%$$"$%#$&&2.4&5<74,)+'*;/(&/1,.?ACB(54)5&0/6=9;5+&68?@,,0*+*%'$(710*00(%')87:-//))-78:<BG>ACEB>@?>9BE;(*(%$/71177002GMA--66;>75/1-25=<<$)0-(('((((03002;1(/%%#"&&"$&#&/2870/<666=?83...24128+124>:4*"###%%%&&&%('$6289<9446373;9;:A;9./BA97<>>4-/)&&&056?>;>;9;//<DDB92146CE?(+6@B7,;;92/-04)+)0A:9217(58748<;;784'5DED=C96==>;<=B>>;==CFCSG>8<878<9:<>B<@A@86JN:'.=9C;;))>.A<=;CB*.&61;*+,:&5;58%&%23-+10-/,2.&%#))*,-,**58;;143/0*++,(%.3,/*-()/64?6458)/3+/$%0/*')(7;<>?=;40;=??=6876:23834436457A<+$#$$*-(+4(38/0($.%'$&%%*-.422;7$'$<?:8175;D90;7%'.-.99<7=?2&=DFEEA/80<10+=>DBAHD;<:==AD@C@<0.*22EJ;77'14544&&,00/0328/15',49;?BJ77?@7749:*(%''.'*(-,2)595CA:AB=&(('.++,((4-/)&/++7=736$*35:99<6745%.($'#$#$$'&(%391--$*%(.%'&.1,'-788=:>?2(8/('>654GA:22*$$$$')'&+>@I;'7<A<<>A947.;*47(*788=C>9BC;:DC@>C<F::+,-1,;67:<?,7A@*)'69DDLC;8(2::95*0/$%*,&/$&'7?>88(%%&0(&59</220-/1%&,*(0))();67).,0*).))=955?=0/$$(+')(1//-8259866<7,@@<;/++(&'(-&(((,8<<=;-%'#&#%'),*&#,+,&&)$&&)-(%%*(%5/(-(.33<56&.=60%2?B1*B;>?:@DGB@=/&%3-+9&2786::45?=952-58:;;<8;=<;<66..5.///+'$%88711,+,--('0*%$%&&515-+&+'(.**C799;M?9&)D<3(+>:5./:=>=5;//')239012*)$$&94637///1/.(/((.&)$)&362+/).1,(('0CCHB9@;GC8/*32575/><5(.31&*311()-5;6:<;890+1+;2,*%%/?<?924(/)('+A<?A@9207:C?FHRE877<B9@8:?:9@9:510&(&'),*-'$$(9>B?5557+2B@?=DK==BC?@;>76(04@ECABB&)5)BVBEE=<<:6(,==&&50;:3&&$(//(3367@G?=<A8:=<A?3.78551&&%#''05934@@?A>AEKA>1)??74>?@AA?A==<<7:))%#'&%$$%(%$',1225=JCAAL6+&&0448'&(.26312*,/17))2116786.*)(//.%('036?9*)7'&)*'035%"%(22/-.=56/-33/-222279?@2>;6?=@=FC<;;:@;A=E@?870%$$&-3,5I@B69*,*@C:59;225/4((3/./58374-2+,0(00.%%##'$$$'''29,(&0/9:=>A===BA7;7<81.<<6@==>;?=>><?<D;EH.*1;:23+2@774&/((+.-'&*%&''&)+054558@B>8**3$)-02-&''##'&)&&'&&(,>A:22=/,%7>54.&,%00%#36123)*.$,.&.%$$(*995448:A?9;89:436()/278;-'')(/62667:@>A=>=:892+24)21+334&>7@AC,(,5693)$%$$--,+"%$&%)(&$%'*87;1519F:?@A9B14.09:BDD=8755BE54A=797;=D@B/E>AB89;)6()(+%&$)))-'''&.899--326---($&1+65@C??E@A1E3>;BB>%%+;BDF?@==/($%%$.0<>@6,*??&/7069,*%4*&+15?622*.(*;4@D:5,.48=*14+376,-./9..-(+$##'%#%$#%%'&/(-467@H@;C<:<<:')($,,,,1(%2<>7)228@@C<<PG=;21/;8<>6;B5-22,($&$&*+72,.#&(%%&&&)69=?89-.*/*-/%&9:ABC900967/.%/-+38%%,+$%).$%$%0)/%#%$&%&&(-'(((&5:;<?AAB@A.3-<5<NHA;**)/2>A:9B>><><<>AD%?8945?;EFE;7=B>=<=@CAE/,/)*.40.8%&16==76&&+3131+,-,,(((39:178ACD?6:89,&(''(./,1.32572&*.(.144*-%+$$556..49:=4:0)+3+%/6<=?HF?IB>G@EB=?A;?63-+-(&300%$'.,0.-*,/0,,+--*''+,+%''(&*011259<;(%(%$&9::<9,+#$$$)#$*+9)0-;0//4%$**)((6/;1+)&.('0')$'+)&1.54/@>5664)'+&**&'())**)'))%$#%'+*&+$&$$$$#(###$-'/*&-(%$(,)&.-.&842&'359;:<0/0.'%'3/0105%.%887*&()%*019.);=BCD9<D4<4946*%$&%'%$35<7-586,,(3'))$((&++1%-)))(##&()*%**)$$$$$',%'($#%&%')+'#')*,+,%%*(((')$*%#%&0%'62437$%#('(,0+&--'-%&0/,$.ECB?@988,9()+$'2'**+.+%%*-;78:;=10,#&&/'('%&$%%)')1)(&',23++(%$&,,+,('0000/&&6:;845011#&(/,3.+,1&'&(()&$)-'$&*$&$$+$$&%%&)*++++210/1*$#$.,22;<-@@@<<)<'?+'6))34$3($(&((+-,6$$//-(:>8@1?=<994$*5:4&+D>@C2-2?4/*7;9?97-(&$&&$$&&&*+#$&,,'&'(,,)-/8>90)*$%&12+69$**%*3&%&$()166?>?1IDCD6//825<5'A@C=BAM6:56587A49722.>)2:1,2-,++%01:=>AB>6<.-31161>(-0*56006+8%%%%%8&-::?C=DC43.-.$'(*1()12&'(,/+2443.-0&&'$%-96@?<>99%(%142105**$%339><AC<>>14466>=37155;86-A;74/.71/@88HJ;;/$174;-,/*%&'&'$$$%&&&+=/37//ECEC80.$$(+5876A<11/(%#+.*,&)198892)(&&#$+<:5736&623?4<4<@A@;>:<<;2.&$$4557774:=.-($&44669:83567>D9;8B>B7:(+,79<7::*10&%-/705>((8,89:*(%$$+(*39;,%+0423237F4.=/=<:770&06>A;6+('/'('.%&-1&169;-.:9840($*) -@04a11cd4-a588-4369-a396-ffe54819e518 -GTAATACTTCGTTCAGTTACGTATTGCTGCGCGCGCACTCTCTGTCGTCAGCAGCGCGTCAGATGTAATATAAAGAGAACAGGTCGTTCGACTGCGGCGAGCGGTGTCAGCTCGCTCAAAAGCATTAATACGATTATCCACAGAATCGGGGATAAAGTCGGAAAGAACATGTGAGCAAAGCAAAGCACCGGAGGAAACCAGCGCCGCAGACGTTTGCACCCATAGGCTCCGCCCCCTGACGAGCATCACAAAAATCGACGCTCAAGCCAGAGGTAAGCGAAACCCGACAGGACTATAAAGAGATACCAGGTGTTTCCTGAGCTCCCTCGTGCGCTCTCTGTTCGACCCTGCCGCTACCGGATACCTGTCCGCCTTTCTCCCTTCGGGAAGCTGGCGCTTTCTCGTAGCTCACGCTGCTTGGGTATCTCGGTTCGGTGTAGATCGTTCCTCCAAGCTGGGCTGTGTGCACGAACCCCAGATCAGCCGAAACCGCTGCGCCTTGTCCGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACAAAGCGCCACTGGCGGCAGCCATTGGTAAAAGTCGAGTGTGCGAGAGGTCAAGAAGTACTTGAAGTGATGGCCTGACTACAGCTACACTGAAAGGACAGTTTTGGTGACTCGTCTCGCACAAGACAGTTACCTGGTTAAGCAGTTCCCAACTGACTTAACCTTCGATCAAACCACCTCCCCAGGTGGTTTTCGTTATTTCAGTTTAGGGAGATTGACCAGAACACAATAATCACAAGAAGAAACTCCGACAAACTGGTTAAAATCAATCAAACAGGACTATAAAGTAATATTATTTTGATTATACTTCTAGAGAGAAACAGTGGCATAGTGATGCATAAATAAACACATTATCACTATGTAAACGTAAACAGAAATGGAGAGCAAGTTTAAACATGATAAAGAGATATCATAAAAATTTTAAGTGTTTCCGAAACATAACTCTCAGAGCAACTAAAAACACTTAATGTAATATCCGGAAAAAACAACTTTAGGAAAACATCGTTTGATATTAGACGCGATATTTTCATTTTATGACGTAAAAAACCCAGCAGCTCTGTTAAAGTAAAAAGCTTTAGAAATGAAGCATCTCTTTTAAATAAAGAAAACTCATTTGGGATAGCTATTTTTATAACATGGACACATCCAAAGAAAATGTCCATAACAATAGAGATGAAAGGTCAAGTAACACAAAAATACTCAACGATAGATAACACACAAAGTGAATCAAGCGTGTCCCTCAATGTTGAGTCAATATTATCAAACACCCCTCCATTGCGACAAACCCTCGGCTCTCTCAGGAAAAGGGAATGTTTTAATGATTAAGGTTAGTAGAAACACAGAACGGAAAAAGAAGAACCCCCAGAAGGGTGATTACTATAAAATAACACAAAAGCACAAAGAAATAAACGGAGAAATAAAACAAACTAAAAAGGTAAGCTATATGAATTCAAAGCCACCCAGCGATAATAACCACATCAAGAAACATAAACAAAGAAACAACGATAAAAAACGTATCAAAACTACTAACACAAAAAAGAAAAGATGAAATAATAGGCAACCTAAAAAGAATAGATAATAGAATTAACGATATTGCAATAATAACCCAGCAGATCAAAACAAAGAGATTTTTAGATATAGGACTAAGTGAATTCAAATGAAATATCAATGCTTGGTGAAGGAGTAAGCAGGCGCTGTCTTTCATTAGCTCAATCTTAGTTTAAAGACTCAATTATTCTCATTGATGAGATGAAAATGGAATTCATTACTCAGTAATCAAAGATATAAGTCAGCACTTTGATAGAAGCAGCAAAACCAATAATAATCAAATATTTACAACAACACACAGCCATGATGTAATATGTGCGATAAACGAATTAAGATGAAAAAAGAAAAAGATATATCTTACATAAGACTAGGAAGAACAAGGAATCTCAAAAACCTACAGCAATGCAATTTAACATGGATGATTTTCTTTTCAGTTAGAAAATGGCTGAGAGGTGAGATAAATGAAACCGAGAAAAATAAATGATTATAAAAAGTCATTTTCGTTGAGGTGATGATGATTTTCACTTCCTTTGCAATCTACTTGAAATAGAAGGAATTAATGATGTTTATGTTGAAAAAATAAAATGGAAGGAAACTAAAACAAACCCTTACAGAGCATTTAAAAGCATAGAGTCTTTTAATGAAAAGAAAGTATATTCTTAATCATCGATGCCGACGAATGTTTCTGACACGGAAAGATCGATAATTCAACATTAAATAGGCTTAACATTTCATCACCAAGCTCGCATAATGAAATATTGCGTAACGGAAGCACAAAAATATCTTCTTTATCATGCCAGGAAAAAACAAAGAATAGCGCAATAGAAGATCTAATCATTGCTCACGCGTAATAAGAAAGAGGTGTTTAGATATATAGACGATCTATTCAATAAAATAAAAGAACAAGAATCTATTATTACATCCTTAGATCCTGATTACGCTTGCAAATAATGAAAAGAAAGCAAAGTTCAAGTTTACCTTAGTTGTAATAAGGAATCAGATTCTAGAATAGGCATATCAATGAAGAACAAAACCATTGATACTGACGATGACTGCTTCAGTGAGATAAAAGAATTTATATCAAAAGTATGAAACAACTCCACCTACAAAATCATAGCGCAATGACTAAAGACGAATTATAAAATTTAACATAATGCTGTAATTGTACGCACCGCTGAAACGCGCTGAACGCGATTCTGACGCAGACACGCAAAAGAGATGTTTTACCCCGGGAAAACAGGAAGGATGCGTCGAGATCGTTTTCAGCGCTCACTGTAGCTATGCATGAAAGCGAATGGTGATCAGCACGGGAGCTTACGTTGTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCGGGAAGCTAATCTGCCATAAAGTCTGGATAACAGGGCACGGTGATACTCCGTAATAGCTGATCAGCACCTCCGCATACTCCCTGTCCCCGACGCTTGCCGTCGATGATTTTCTGTAACGCCCCCAGTCCTCATAACTTCTTTCTGTACCCGATCATCAGTCAGTGGGGTTAACTTTCTTACCGAGAGCTGCCGCCCCGTAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCGCTTTTCTGATTTCCTGGTCTTCTTCTGCCGTCAGATGAACAGGGCAGGCTGATAGCCCGCCTGCGCGTATTACTTCCACTTCGTTTTGTCATAAAACATGGCTCCGTATCTGACATGGTGTCGGGGCGAAAGCCCTGATAGGGCAATTGTAATAGCGTGCATGTATGCGCGGTATAACAATTGCACATCCTGTCCTGTCAGCAAGCTCGAATTACCGACGAGAACTGCGGCAGTTTTTTGGCAGTGACAGTGTTGTCTGACAGAAATGCCGTCAAAAAGCCAAGCGGCAGAATAACGGCAGCAAAACAGTCGAAAAAGTGGTACGCGATATAATCACACCTGCATCTCGCCCCCTTACACATCTGACGCTGCCGACGACAGAGTGCGCGCGCAACAATACGTAAC -+ 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-CGTTGTACTTCGTTCAGTTACGTATTGCTACGCGCGCACTCTCTGTCGTCGGCAGCGTCAGATATTATAAGAGACAGTGATACTCCGTAATAGCGATCAGCACCTCCGCATACTCCCTGTCCCGACACGCTTGCCGTCGATAAAGAGTTTTTTCTGTAACGCCCCAGTCCTCGCCAACTTCTTTCGGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTACCGAGAGCTGCCGCCCGTAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCTTTTTTCTGATTTCCTGGTCGCTATTATAACACCGTCAGACGAACAGGGCACGACTGATAACGCCGCCTGCGCAGTATTATATCCCACTTCGTTTGTCGCCAAACATGGCTCCATGCTATCTGACACATGGGTGTCCAGGGCAAAGCCCGACCAGGGCAGTGTAATAGCGTGCATGTATGCGCGAGGCATAACAATTGCACATCCTACTCTGTCAGCAAGCTCGAATTACCGACAAAGGCACGGCAGTTTTTGGCAGTGACTTAGTGTTGTCTGACAGAAATGCCCGTCAAAAGCCAAGCGGCAGAATAACGGCAACAAAACAGTCGAAAAGTGGTACGCGATATAATCACACAACGCAGATGACAGACAGAACGGAGAAAAACGAAAAAGATGAACGAACGCGGCAGCAAGCCGGCGATCAACATGGCGGGATTCGCCAAAAAGTCAGAGCCTGACGCTGCTCGAAAAACTGGACGCACCGATGCTGACGAACGGGCTGCCGTATTGAAGCTGCACGAACTCGCAGAAGAACTCCAGAACAGCATCCAGACACGCTTTGAAGTAGAAAATAGCACGGAGAGATAACGCTCAGGACAAGGATGCCGAACAGCACAACAGAGCGTAAGGAAAATGTCACATAAGGCGCTCTTCGCTTCCTCGCTCGCGACTCGCTACGCTCGGTCGTTCGACTGCGGCAGAGGCGGTGTGGCTTCACTCAAAGCGGTAATACGGTTATCCACAGAATCAGCAGGATAAAGTCGGAAAGAACATGTGAGCAAAAAGAAGCAAAGCACCGGAGGAAGCCAGCGCCGCAGGCGCGTTTGCCATAGGCTCCGCCCCCTGACGAAACATCACAAAAATCGACGCTCAAGCCAGAGGTGGCGAAACCCGACAGGACTATAAAGATGTGCAGGTGTTTCCCCCTGGGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCCGGTTCGGTGTAGGTCGTTCGCTCAAGCTGGGCGCTATTGTGCACGAACCCCGTTCAGCCCGACTAACTGCGCCTTATCCGGTAACTATCGTCTTGAGTCCAACCCGGTAGAGACACGACCAAAGCGCCACTGGCGGCAGCCATTGGTAAAAGTCGATGTGCAGGAGTTCAAGAGAGTACTTGAGTGATGGCCTGACTACAGCTACACTGAAAGGACAGTTTTGGTGACTCGTCTCGCACAGACAGGATTACCTGGTTAAGCAGTTCCCCAGCGGCAACCTTCGATCAAACCACCTCCCCAGGTGGTTTTCGTTTTCAGTTTGGGAGATTACGACCAGAACACAATAATCACAAGAAGAAACTCCGACAAACTGGTTAAAATCAATCAAACAGGACTATAAAAATATTATTTGATTATACTTCTAAGAAAAGAAACAGTGGCATAGTGATGCATAGAACAAACACATTATTACTATGTAAACGTAAACAGAATGGAGAGCAAGTTTAAACATGATAAAGATATCACTTAAAAAATTTTTAAAGTGTACAAGAGAAACATAACTCTCAAACAACTAAAAAACACTTAATGTAATATCCGGAAAAAACAACTTTGGGAAAACATCGATAGACGCGATATTTTCATTTTATGACGTAAAAAACCCAGCAGCTCTGTTAAAAAAGTAAAAAGCTTTAGAAATGAAGCATCTCTTTTAAATAAAGAAAACTCATTTTGGGATAGCTATTTTATAACATGGACACATCAAAGAAATGTCCATAACAATAAGAGATGAAAGGTCAGAAGTAACACAAAAATACTCAACGATAGATAACACACAAAGTAGTCAAGCGTGTCCCTCAATGTTGAGTCAATATTATCAAACACCCCTCCATTGCGACAAACCCTCGGCTCTCAGGAAAAGGATGTTTTAATGATTAAGGTTAATTGAAACACAAGAACGGAAGAACCCCCAAGAAGAATTGTTACTATAAAATAACACAAAAGCACAAGAAATAAACGGAGAAATAAAACAAACTAAAGAATTAAAGCTATATGAGATTCAAAACCGCAGCGATAACCACATCAAGAAACACTAAACAAAAACGGCAACGATAAAAAAACGTATCAAAACTACTAACACAAAAAGAAAAGATGAAATAATAGGCAACCTAAAAAGAGATAGATAATAGAATTAACGTGTTGCAATAATAGCAACAGATCAAAACAAAGAAGTTTTAGATATGGGACTAAGTGAATTAAATGAAATATCAATGCTTGGTGAAGAGGTAAGCAAACGCTGTCTTTCATTAGCTCAATCTTAGTTCAAAAGACTCAATTATTCTCATTGATGAGATAGAAAATGGAATTCATTATAGTAATCAAAGATATAATCAACGCTTTGATAAAAACAGCAAAAACCAATAATAATCAAATATTTACAGCAACACACAGCCATGATGTAATATGTGCGATAAACGAATTAGATGAAAAAAAAGAAAAAGTGCATATCTTACATAAGACTGGGAAGAACAAGGAATCTCTCAAAAACCTACAGCAGACGTATTAGTTTAACATGGATGATTTTTCTTTTTCAGTTGAAAATGGCTGTAGGATGAGATAAATGAAACCGAGAAAAATAAATGATTATAAAAAGATCATTTTCGTTGAGGAATTGATGATGAGATTTTCACTTCCTTTGCAATCTACTTGAAATAGAAGGAGTGTATGATGTTTATGTTGAAAAAATAAATGGAAAGACAAAACTAAAACAAACCCTTAAGAGCATTTAAAAAAGCATAGAGTCTTTTAATGAAAAGGAAAGTATATTATACTTAATCATCGATGCCGACGAATCGTTTCTGACACGGAAAGATCCGATAATTTCAACATTAAATGAGCTTAACATTTCATCACCAAGCTCGCACACAATGAAATAGCCATTGACGAAGCACAAAAATATCTTTCTTTATCATGCCCGGGAAAAAACAAAGAATGGCGCAATGAAGATCACAATGTTGCTCACGCGTGTAAGAAAGAGGTGTTTAGATATATAGACGATCTATTCAATAAAATAAAGAACAAGAATCTATTATTACATCCTTAGATCCTGATTACGCTTACCCAAATAATGAAAAGAAAGCAAAAGAGTTCAAGTTTACCTTAGTTGTAATAAGGAATCAGATTCTAGAATAGGCATATCAATGAAGAACAAAACCATTGATACTGACGATGACTTTGCTTCAGTGAGATAAAAAAAATTTATATCAAAAATATGAAACAACTCACCTACAAAATCACTTAGCGCAATGACTAAAGACAGTTACTCGTTTAACATAATGCTGTGGTGTACGCACCGCTGAAGCTTAACGCTGAACGCGATTCTGACGCAGACACCGCAAAGAATGTTTACGGGAAAACAGGAAGGATGCGTCAGGATCGTTTTCAGCTCGCTGCATATATGCATGAAAGCGAATGGTGATCGCCTGGGAGCTTACGATTGTTCATACCGTCTGTTTTCGACAGTTTTTCTCTCCGGGAAGCTAATCTGCCATAGTCTGGATAACAGGGCACGGTGATACTCCTGTCTCTTATACACATCTCCGAGCCCACGAGACCAGAGAGTGCGCGCGCAGCAATTACGTAAC 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-GTTGTACTTCGTTCGAGTTTACGTATTGCTGCGCGCGCACTCTCTGGCGTCAACGGCGTGAATATTATAAGAGGCAATCATTACTCGAGTAATCAAAGATATGATCAACGCTTTGATAGAAGCAAAAACAATAATCAAATATTTACAACAACACAGCCATGATGTAATATGTGCGATAAACGAATTAGATGAAAAAAAGAAAAGATATATCTTATAAGACTGGGAAGAAGACAAGGAATCTCAAAAACCTACAGCAATGCAATTTAACATGGATGATTTTCTTTTTCAGTTGAAAATGGCTGGGAGGTGAGATAAATGAAACCGAGAAAAATAAATGATTATAAAAAAAGTCATTTTCGTTGAGGGTGATGATGATTTTCACTTCCTTTGCAAATCTACTTGAAATAGAAGGAATTAATGATGTTTATGTTGAAAAAATAAATGGAAAGACAAAACTAAAACAAACCCTTAGAGCATTTAAAGCATAGAGTCTTTTTAATGAAAAAGAAAGTATATTCTTAATCATCGATGCCGACGAATCGTTTTCTGACACGGAAAGATCGATAATTTCAACATTAAATGAGCTTAACATTTCATCACCAAGCTCGCATAATGGAAATATACATTAACGGAAGCACAAAAATATCTTTCTTTATCATGCCAGGAAAAAACAAAGAATGGCGCAATAGAAGATCTAATCATTGCTCACGCGTGTATCAAGAAGAGGTGTTTAGATATATAGACGATCTATTCAATAAAATAAAGAACAAGAATCTATTATTACATCCCTTTAGATCCTGATTACGCTTACCCAAATAATGAAAAGAAAGCAAAAGTTCAAGTTTACCTTAGTTGTAATAAGGAATCAGATTCTAGAATTAGGCATATCAATGAAGAACAAAACCATTGATACTGACGATGACTGCTTCAATTGAATAAAAGGAATTTATATCAAAATATGAAACAACTCCACCTACAAAATCATAGCGCAATGACTAAAGACAATTATAAAATTTAACATAATGCTGTAGTGTACGCACCGCTGAAACGCGCTGAACGCGATTCTGACGCAGACACCGCAAAGAGATGTTTTACCCCGGGAAAACAGGAAGGTTACGTCAGGATCGTTTCATCGCTGCAACTATACATGAAAGCGAATGGTGATCACTTTGGGAGCTTACGGTGTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCGGAAGCTAATCTGCCATAAGTCTGGATAACGGAGCACGGTGATACTCCGTAATAGCGATCAGCACCTCCACCCATACTCCTGTCCCCGACACGCTTGCCGTCGATAAAGTTTTTTCTGTAACGCCCCAGTCTCTTAACTTCTTTCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTACCGAAGAGCTGCCGCCCGTAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCTTTTTCTGATTTCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATAACCCGCCTGCGCGTATTACTTCCACTTCGTTTGTCATAAACGCTGGCTCCGTATCTGACATGGGTGTCGGGGCAAAGCCTGATGGAACGGTGTAATGGCGTGCATGTATGCGCGGTATAGCAATTTGCACATCCTGTCCTGTCAGCAAGCTCGAATTACCGACAAAGGCACGGCAGGTTTTTGGCAGTGACAGTGTTGTCTGACAGATGCCCGTCAAAAAATGACGGCAGAATAACGGCAACAAAACAGTCGAAAAGTGGTACATGATAGAAATCACACAACGCAGATGACAGACAGAACGGAGAAAACGAAAAGATGAACAAGCAGCAGCAAGCCGTACTCAACATGGCAGGATTCGCAAAAAGTCAGAGCCTGACGCTGCTCGAAAAACTGGACGCACCCGATGCTGACGAACAGGCTGCCATGTGTGAAGCTACACGAACTCATGAAGAACTCCAGAACAGCATCCAGACACGCTTTGGAAGTAGAAAATAGCACAGAGAGATAACGCTCAGGACAGGATGCCGAACGGCACAAGCAAACGTAAGGAGAAAATGTCACATAAGGCGCTCTTCCGCTTCCTCGCTCACTGACTCGCGCTACGCTCGGTCGTTCGACTGCGGCGAGCGGTGTCCAGCTCACTCAAAAGCAGTAATACGGTTATCCACAGAATCGGGGGATAAAGTCGGAAAGGACATGTGAGCAAAAAGCAAAGCACCGGAGGAAGCCAGCGCCGCAGGCGTTTTCCATAGGCTCCGCCCCCTGACGAGCATCACAAAAATCGACGCTCAAGCCAGAGGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGTGTTTCCCCTGGGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCTTCGGGAAGCGTGGCGCTTTTCTCATGGCTCACGCTGTAGGTATCTCGGTTCGGTGTAGGTCGTTCGCTCAAGCTGGCTAGCTGACCGCACGAACCCCCCGTTCAACCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACAAAGCGCCACTGGCAGCAGCCATTGGTAAAAGTCGATGTGCAAGAGAGTTCAAGAGAGTACTTGAGGTGATGGCCTGACCACAGCTACACTGAAAGGACAGTTTTGGTGACCGTCTCGCACAAGACAGTTACCTGATTAAGCAGTTCCCCAACTGACTTAACCTTCGATCAAACCACCTCCCCAGGTGGTTTTCGTTTTCAGTTTAGGAGATTACGACAGAACACAATAATCACAAGAAGAAACTCCGACAAACTGGTTAAAATCAATCAAACAGGACTATAAAGTAATATTATTTTGATTATACTTCTAGAAAAGAAACAGTGGCATAGTGATGCATAAATAAACACATTATTACTATGTAAACGTAAACAGAAATGGAGAGAGCAAGTTTAAACATGATAAAAGATATCCACTTAAAAATTTTTAAGTGTTTCGAAACATAACTCTCAAACAACTAAAAACACTTAATGTAATATCCGGAAAAAACAACTTTGGGAAAACATCGATATTGGAGCGCGATATTTCATTTATGACGTAAAAAAACCAGCAGCTCTGTTAAAGTAAAAGCTTTAGAAATGAAGCATCTCTTTTAAATAAAGAAAACTCATTTTTGGGATAGCTATTTTTTATAACATGGACACATCCAAAGAAATGTCCATAACAATAAGAGATGAAGGTCAAGAAGTAACACAAAAATACTCAACTTGATAGATAACACACAAAGTGAATCAGACGTGTCCCTCAATGTTGAGTCAATGTTATCAAACACCCCTCCCATTTGCGACAAACCCTCGGCTCTCAGGAAAAGGGGAGGAAATATTTTGATTAAGGTTAGTGAAACACAGAACGGAAAAAGAACCCCCCAAGAAGAATTGATTACTATAAAAATAACACAAAAAGCACAAAAATAAACGGAGAAATAAAACAAACTAATTAAGCTATGAATTCAAAACCGCAGCGATAATAACCACATCCAAGAAACGCATAAACAAAGAAGCAACGATAAAAAACGTATCAAAACTACTAACACAAAAAGAAAAAGATGAAATAATAGGCAACCTAAAAAGAATAGATAATAGAATTAACGATATTGCAATAATAGCAACAGATCAAAACAAAGAGATTTTTAGATATAGGACTAAGTGGGTAAATGAAATATCAATGCTTGGTGAAGAATAAGCAGAGCGCTTTATCTTTCGATAGCTCAATCTTGGTTAAAAAAGACTCAATTATTCTCATTGATGAGATAGAAAATGGAATTCATTACTCAGTAATCAAAGATATGATCAACTTTGATAGAAGCAGCAAAACCAATAATAATCAAATATTTACAACAACACACAGCCATGATGTAATATGTGCGATAAACGAACTAGATGAAAAAGAAAAAGATATATCTTACATAAGACTGGGGAAGAGCAAGGGAATCTCCAAAACCTACAGCAATGCAATTTAACATGGATGATTTTTCTTTTCAGTTGAAAATGGCTGGGAGAGGTGAGATAAATGAAACCGAAAAATAAATGATTATAAAAAGTCATTTTCGTTGGGGAGTGATGATGATTTTCACTTCCTTTGCAATCTACTTGAAATAGAAGGAATTAATGATGTTTATGTTGAAAAAATAAATGGAAAGACAAAACTAAAACAAACCCTTAGAGCATTTAAAAGCATAGAAAGTCTTTTAATGAAAAAGAAAGTATATTCTTAATCATCGATGCCGACGAATCGTTTTCTGACACGGAAAGATCGATAATTTCAACATTAAATGAGCTTAACATTTCATCACCAAGCTCGCATAATGAAATAGCCATTAACGGAAGCACAAAAATATCTTTCTTTATCATGCCAGGAAAAAACAAGAATGGCGCAATGAGATCTCTAATCATTGCTCACGCGTATAAGAAGAGGTGTTTAGATATGCAGACGATCTATTCAATAAAATAAAAGAACAAGAATCTATTATTACATCCTTAGATCACAATTACGCTTACCCAAATAATGAAAAGAAAGCAAAAGTTCAAGTTTACCTTAGTTGTAATAAGGAATCAGATTCTAGAATGAGCATATCAATGAAGAACAAAACCATTGATACTGACGATGACTGCTTCAATTGAGATAAAAGAATTTATATCAAAAATATGAAACAACTCCACCTACAAAATCATAGCGTGACTAAAGATAGTTATAAAATTTAACATAATGCCCTTAATTGTACGCACCGCTGAAAAACGCGCTGAACGCGATTCTGACGCAGACACCGCAAAAGAGATGTTTTGCAGGGAAAACAGGAAGGATGCGTCAGGAATCAGTTTTCAGCTTCGCTGCATAGCTATGCGTGAAAGCGATGGTCACTTTGGGAACTTACGGTGTCGCACCGTCTGTTTTCGACAGTTTTCTCTCCGGGAAACTAATCTGCCATAAGTCTGGATACTGTCTCTTGCCACATCTCCGAGCCCACGAGACCAGAGTGCGCGCGCAGCAATGCGTAAC 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-@67a7d9ec-7322-4ef3-bd72-77f9057efb25 -TCATTACTCGAGTAATCAAAGATATGATCAACGCTTTGATAGAAGCAAAAACAATAATCAAATATTTACAACAACACAGCCATGATGTAATATGTGCGATAAACGAATTAGATGAAAAAAAGAAAAGATATATCTTATAAGACTGGGAAGAAGACAAGGAATCTCAAAAACCTACAGCAATGCAATTTAACATGGATGATTTTCTTTTTCAGTTGAAAATGGCTGGGAGGTGAGATAAATGAAACCGAGAAAAATAAATGATTATAAAAAAAGTCATTTTCGTTGAGGGTGATGATGATTTTCACTTCCTTTGCAAATCTACTTGAAATAGAAGGAATTAATGATGTTTATGTTGAAAAAATAAATGGAAAGACAAAACTAAAACAAACCCTTAGAGCATTTAAAGCATAGAGTCTTTTTAATGAAAAAGAAAGTATATTCTTAATCATCGATGCCGACGAATCGTTTTCTGACACGGAAAGATCGATAATTTCAACATTAAATGAGCTTAACATTTCATCACCAAGCTCGCATAATGGAAATATACATTAACGGAAGCACAAAAATATCTTTCTTTATCATGCCAGGAAAAAACAAAGAATGGCGCAATAGAAGATCTAATCATTGCTCACGCGTGTATCAAGAAGAGGTGTTTAGATATATAGACGATCTATTCAATAAAATAAAGAACAAGAATCTATTATTACATCCCTTTAGATCCTGATTACGCTTACCCAAATAATGAAAAGAAAGCAAAAGTTCAAGTTTACCTTAGTTGTAATAAGGAATCAGATTCTAGAATTAGGCATATCAATGAAGAACAAAACCATTGATACTGACGATGACTGCTTCAATTGAATAAAAGGAATTTATATCAAAATATGAAACAACTCCACCTACAAAATCATAGCGCAATGACTAAAGACAATTATAAAATTTAACATAATGCTGTAGTGTACGCACCGCTGAAACGCGCTGAACGCGATTCTGACGCAGACACCGCAA 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e0998300-6336-4a3d-bb92-51572c44c417 -GTTGTACTTCGTTCCGGTTACGTATTGCTGCGCGCGCGCTCTCTGTCGTCGGCAGCGTCAGATGTGTATAAGAACTTAGGATAACCGTATTACCGCTTTTGAGTGAGCTGACACCGCTCACGCCGCAGTCGAACGACCGAGCGTAGCAGTCAGTGACAGGAAGCGGAAAAGAAGCCCGCCATATGTGACATTTTCTCCTTACGCTCTGTTGTGTCGTTCGGCATCCTGTCCTGAGCGTTATCTCTGTGCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGGAGTTCTTCTGCGGGGGACAGTACAGCTTCTCACACATAGCAGCCTGTTCGTCAGCATCAGGTGCGTCCAGTTTTTCGAGCAGCGTCAGGCTCTGACTTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACACTTTTCGACTGTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTGACGGGCATTTCTGTCAGACAACACTGTCACTGCCAAAAAACTGCCGCGCCTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCATACATGCACGCTATTACAATTGCCCTGGTCAGGGCTTTGCCCCAGGCTTTCACCCATGTCAGATACGGAGCCATGTTTTATGACAAAACGAAGTGGAAGTAATACGCGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACGGCAGAAGAAGACCAGGAAATCAGAAAAGGGCTGCTGAATGCGGCAAGACCGTTTCCGGTTTTTACGGGCGGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCGGGTACTGAAAGAAGTTATGAGACTGGGGGCGTTACCGCGAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGAGTATGCGGAGGTGCTGATCGCTATTACGGAGTATCACCGTGCCTGTTATCCAGCTTGTGAGTTAGCTTCCCGGAGAGAAAACTGTCGAAAACAGACGGTATGAACATTCATCAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGGCTGAAAACTGATCCTGACGCATCCTTCCTGTTTTCCAGGGTAAAACATCTCTTTTGCAGTGTCTGCGTCAGAATCGCGTTCAGCGCGTTCAGCCCGGTGCGTACAATTACAGCGATGTATTAAATTTTATAATTGTCTTTGTCATTGCGCTATGATTTTGTAGAGTGGAGTTGTTTCATATTTTGATATAAATTCTTTTTATCTCACTGAAGCAGTCATCGTCAGTATCAATGGTTTTGTTCTTCATTGATATGCCTATTCTAGAATCTGATTCTTATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTCATTATTTGGGTAAGCGTAATCAGGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTATTTTATTGAATAGATCGTCTATATATCTAAACACCTCTTTCTTACACGCGTGAGCAATGATTTAGATCTTCTATTGCGCCATTCTTGTTTTTTCTGGCATGATAAAGAAAGATATTTTTGTGCTTCCGTTAATGGCTATTTCATTATGCGAGCTTGGTGATGAAATGTTAAGCTCATTTAATGTTGAAATTATCGATCTTTCCGTGTCAGAGAAAACGATTCGTCGGCATCGATGATTAAGAATATACTTTCTTTTTCATTAAAAGACTCTATGCTTTTAAAATGCTCTAAGGGTTTGTTTAGTTTTGTCTTTCCATTTATTTTTTCAACATAAACATCATTAATTCCTTCTATTTCAAGTAGATTGCAAAGGAAGTGAAAATCATCATCACCCTCAACGAAAATGACTTTTTATAATCATTTATTTTTCTCAGTTTCATTTATCTCACCTCCCAGCTTCATTTTTCCAACTGAAAAAGAAAAATCATACCATGTTAAATTGCATTGCTGTAGGTTTTTGAGATTCCTTGTCTCTTCCCCAGTCTTATGTAAGATATATCTTTTCTTTTTCATCTAATTCGTTTATCGCACTTAAACCCATCGCTGGCTGTGTGTTGTTGTAAATATTTGATTATTATTAGTTTTTTGCTCGCCTATCAAAGCGTTGATCATATCTTTGATTACTGAGTAATGAATTCCATTTTCTATCTCATCAATGAGAATAATTGAGTCTTTTAGACTAAAGATTGGGCTAATAGAAAGACAGCGCTCATAACACTCCTTCACCAAGCATTGATATTTCATTTAATTCACTTAGTCCTATATCTAAAAAAATCTCTTTGTTTTTGATCTGTTGCTATTATTGCAATATCGTTAATTCTATCTATTCTTTTTAGGTTGCCTATTATTTCATCTTTTCTTTTTTGTGTTAGTAGTTTGATACGTTTTTATCGTTGCTTCTTTGTTTATGTTTCTTGATGTAGTTATTATCGCTGCGGTTTTGATTCATATAGCTTACACCTTTTTTTAGTTTGTTTTATTTCTCCGTTTATTTCTTGTGCTTTTGTGTTATTTTTATAGTAATCAATTCTTCTGGGAGTTCTTTTTCCGTTCTGTGTTTCACTAACCTTAATCATTAAAACATTCCCTTTTTTCCTGAGAGCCGAGGGTTTGTCGCAATGGAGGGTGTTTGATAATATTGACTCAACATTGAGGACACGCTTGATTCACTTTGTGTCAGTATCTATCGTTAGTATTTTTGTGTTACTTCTGACCTTTTTCATCTCTTATTGTTATGGACATTTCTTTGGATGTGTCCATCTTCTTAAAATAACTATCCCAAAATGAGTTTTCTTTATTTAAAGAGATGCTTCATTTCTAAAAAGCTTTTACTTTAACAGAGCTGCTGGGTTTTTACGTCATAAAATGAAAATATCGCGTCTAATATCGATGTTTTCCCAAGTTGTTTTCCGGATATTACATTAAGTGTTTTAGTTGTTTGAGAGTTATGCTCTCGAAACATAAAATTTTTAAGTGGATATCTTTTATCATGTTTAAACTTATCCATTTCTGTTTACGTTTACATAGTAATAATGTGTTTATTTATGCATCCACACTGTGCACTGTTTCTTTTCTAGAAGTATAATCAAAATAATATTACTTTATAGTCCTGTTTGGATTGATTTTAACCAGTTTGTCTATTCAGTTTCTTCCTTTGATTATTGTATTTCTGAGTGTAATCTCCTAAACTGAAAACGAAAAAACCACCACCGGAATTTGATTTTGATCGAAGGATTAAGTCAGTTGAGGGCTTCTTGGCAGGTAACTGTCTTGTGCGAGACAGAGTCACCAAAACTGTCCTTTCAGTGTAGCTGTAGTCAGGCCATCGCTGCTAGTACTCTCTTGAACCTCTCGCACATCGACTTTTACCAATGGCTGCTGCCAGTGGCGCTTTGTCGTGTCTTACTGGGTTGGACTCAAGACGATAGTTACCGGATAAGGCCTGTCTCTTATACACATCTGACGCTGCCGACGAAGAGGCGCGCGCACTCTCTGTCGTCGGCAGCGTCAGATGTGTATAAGAGACGCTGATTATCCACAGAATCGGGGATAAAGTCGGAAGAACATGTGAGCAAAAGCAAAGCACCGGAGGAAGCCAGCGCCGCATTTTTCCGCAGGCTCCGCCCCTGACGAGCATCACAAAAATCGACGCTCAAGCCAGAGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGTGTTTCCCCTGGAAGCTCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCGCTTACCGGATACCTGTCCGCCTTTCTCGCTTCGGGAAGCATGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCGGTTCGGTGTAGGTCGTTCGCTCAAGCTGGGCTGTGTGCACGAACCCCGTTCAGCCGACCGCCGCGCCTTATCCGGTAACTATCGTCTTGAGTCCAACTGAGTAAGACACGACCAGCGCCACTGGCAGCAGCCATTGGTAAAAGTCGATGTACGAGAGGTTCAAAGTACTTGAAGTGATAAGCCTGACTACAGCTACACTGAAAGGACAGTTTTGGTGACTCGTCTCGCACAAGACAGTTACCTGGTTAAGCAGTTCCCCAACTGACTTAACCTTCGATCAAACCACCTCCCCAGGTGGTTTTCGTTTTCAGTTTAGGAGATTACGACCCGAACACAATAATCACAAGAAGAAACTCCGACAAACTGGTTCAAAATCAATCCAAACAGGACTATAAGTAATAATTATTTTGATTAGCTAGAAAGAAACAGTGGCATAGTGATGCATAAATAAACACATTATTACTATGTAAACGTAAACAGAAATGGAGAGCAAGTTTAAACATGATAAAGATATCACTTAAAAATTTTAAGTGTTTCGAGCATAACTCTCAAACAACTAAAAACACTTAATGTAATATCCGGAAAAAACAACTTTGGGAAAACATCGATATTAGACGCGATATTTTCATTTTTATGACGTAAAAAACCCAGCAGCTCTGTTAAAGTAAAAAGCTTTAGAAATGAAGCATCTCTTTTAAATAAAGAAAACTCATTTGGGATAGCTATTTTTATAACATGGACACATCCAAAGAAATGTCCATAACAATAAGAGATGAAAGGTCAGAAGTAACACAAAAATACAACGATAGATAACACACAAAGTGAATCAAGCGTGTCCCTCAATGTTAGTCAATATTATCAAACACCCCTCCATTGCGACAAACCCTCGGCTCTCAGGAAAGGGGAATGTTTTAATGATTAAGGTTAGTGAAACACAGAACGGAAAAAAGAACCCCCAGAAGAATTGATTACTATAAAATAACACAAAAGCACAAGAAATAAACGGAGAAATAAAACAAACTAAAAGGTAAGCATAGCCAGTTCAAAACCGCAGCGATAATAACCACATCAAAAACATAAACAAAGAAGCAACGATAAAAAACAGTATCAAAACTACTAACACAAAAGAAAGATGAAATAATGAGCAACCTAAAAGAATAGATAATAGAATTAACGATATTGCAATAATAGCAACAGATCAAAGTAAAGAGATTTTTTTTTTAGATATAGGACTAAGTGAGATTAAATGAAATATCAATGCTTGGTGAAGGAGTAAGCAGGCGCTGTCTTTCATTAGCTCAATCTTAGTTCAAAAGACTCAATTATTCTCATTGATGAGATAGAAAATGGAATTCATTACTCAGTAATCAAGGTGATCAACAACTTCACGATGAAGCAGCAAAAACCAATAATCAAATATTACAACAACACACAGCCATGATGTAATGTGCGATAAACGAATTAAGATGAAAAAGAAGAATATGCTTACATAAGACTGGGAAGAGACAAGGAATCTCAAAAACCTACAGCAATGCAATTTGTTGCTTTTCAGTTGAAAATGGCTGGGAGGTGAGATAAATGGAAACCGAAAAATGATTATAAAGTCATTTTCGTTGAGGAGTGATGATGATTTTCACTTCCTTTTTGCAATCTACTTTGAAATAGAAGGAATTAATGATGTTTATGTTGAAAAATAAATGGAAAGACAAAACTAAAAACAAACCCTTAGAGCATTTAAAAACATAGAGTCTTTTAATGAAAAGAAAGTATATTCGCTCCAATCATCATTACCGACGAATCGTTTTCTGACACGGAAAGATCGATATTTCAACATTAAATGAGCTTAACATTTCATCACCAAGCTCGCATAATGAAATAGCCATTAACGGAAGCACAAAAATATCTTTCTTTATCATGCCAGGAAAAAACAGAATGGCGCAATAGAATCTAATCATTGCTCGCGTGTAAGAAGGAATGTTTAAATATATAGACGATCTAGCTCAATAAAATAAAGAGCAAGAATCTATTATTACATCCAGCAGATCCTGATTACGCTTACCCAAAATAATGAAAAGCAAAGTTCAAGTTTACCTTAGTTGTAATAAGGGAATCAGATTCTAGAATAGGCATATCAATGAAGAACAAAACCGACAATGCGAAGCGATGACTGCTTCAGTGAGATAAAGAATTTATATCAAAAATATGAAACAACTCCCACCTACAAAATCATAGCGCAATGACTAAAGACAATTATAAAATTTAACATAATGCTGTAATTGTACGCACCGCTGAAACGCGCTGAACGCGATTATTACCAGACACCGCAAAGAATATTTTGCAGGAAAACAGGAAGGATGCGTCAGGATCGTTTTCAGCTCGCTGCATAGCTATGCATGAAAGCGAATGGTGATCACTTTGGGAGCTTACGGTGTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCGGGAAGCTAATCTGCCATAGAATCACGGATAACGGGCACGGTGATACTCGTAATAGCGATCAGCACCTCCGCATACTCCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTCTGTAACGCCCCCAGTCTCATAACTTCTTTCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTGCGAGAGCTGCCGCCCGTAAAAAACCGGAAACAGGGTCTGCCGCATTCAGCAGCCCTTTTTGCGGTTTCCTGGTCGCTATCTGCAAATCCAGACAAACAAGCGATATCACCTGCACTGCTGACCACTTCGCTAAGTTTGATGAAACGACTCCATTATCGTTCGTAGTGTCGAGGGCAAAACCACAGCCGGGAGCAGTTAATGACTGGCGTTGCGTATCACCAGGCGTATGGCTGGTGCGTCTGTCGCGTCGGCGAGCTCCACCGACAAGCGCGAGCACGGCGATGTTTGTGTTAATCTGACAGAAATGCCCGTCAAAAACAACGATCGGCGAAAGATGACATATATAATCACACAACGGTGACAGTGAGGCAGATGAACGAGCGGCGGCGATCGCCTTCAACATGTGTGATTCATGAAAGTCGAGAATTTGTTGCTTTAACCGGCTGGACGCGCCCGACCAACGACGAGCGAACGCGCCATGTGTGAAGCCCGCGGCTTTCTCAGGCAGCATCCGAAAAACGCATCTTTTGAAGTAAGAAAATAACGCAGAAGAAGATTCAACGCTCAGAACAGGATGCGAACATTTTACAACAAGCATGAAGAAAATGTGCATGGAAACTCCCTCGCACTTTCGCACGCTCGATCGTTCATTATATCTCGCTGCACTTTCAAAAAGCAGTAATACGGTATCTGATCTCTTATACACACATCGACGCCCCCCGCCGACATTTATCGCGCGCAACAATACGTGGC 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-GTTGTACTTCGTTCAGTTACGTATTGCTGCGCGCCGCCTCTCCTGGTCTCATGGGCTCGGAGATGTGTATAAGAGACAGAAGCGCTGGGCTGTGTGCACGAACCCCGTTCAGCCCGACCGCTGCGCCTTATCCGGTAACTATCGTGCAGGTCAACCCGGTAGGGCGACAAGCGCCACTGGCGGCAGCCATTGGTAAAAGTCGATGTGCGAGAGGTTCAGAGAGTACTTGAAGTGATGGCCTGACTACAGCTACACTGAAAGGACAGTTTTGGTGGCTCGTCTCGCACAAGACAGTTACCTGGTTAAGCAGTTCCCCAACTGACTTAACCTTCGATCAAACCACCTCCCCAGGTGTTTTCGTTTTCAGTTTAGGAGATTACGACCAGAACGCAATAATCACAAGAAGAAACTCCGACAAACTGGTTAAAATCAATCCAAACAGGACTATAAAGTAATATTATTTTGATTATACTTCTAGAAAAGAAACAGTGGCATAGTGATGCATAAATAAACACATTATTACTATGTAAACGTAAACAGAAATGGAAACCAAGTTTAAACATGATAAAGATATCCACTTAAAAAATTTTAAGTGTTTCGAAGAGCATAACTCTCAAACAACTAAAAAGCTTACTTAATGTAATATCCTGAAAAAACAACTTTGGGAAAACATCGATATTAGACACGATATTTCCATTTTATGACGTAAAACCCAGCAGCTCTGTTAAAGTAAAAAAGCTTTAGAAATGAAGCATCTCTTTTAAATAAAAGAAAACTCATTTGGGATAGCTATTTACATAACATGGACACATCAAAGAAATGTCCATAACAATAAGAGATGAAGGTCAGAGTAACACAAAATACTCAACGATAGATAACACACAAAGTGAATCAAGCGTGTCCCTCAATGTTGAGTCAATATTATCAAACACCTCATTGCGACAAACCCTCGGCTCTCAGGGGAAAAGAGGGGAATGTTTTAATGATTAAGGTTAGTGAAACACAGAACGGAAAAAGAACCCCCCAGAAGAATTGATTACTATAAAATAACACAAAAGCACAAAGAAATAAACGGAGAAATAAAACAAACTAAAAGGTAAGCTATATGAATTCAAAACCGCAGCGATAATAACCACATCCAAGAAACATAAACAAAGAAACAACGATAAAAAACGTATCAAAACTACTAACACAAAAAAGAAAAGATGAAATATTAGGCAACCTAAAGAATAGATAATAGAATTAACGATATTGCAATAATAACCCAACAGATCAAAACAAAGAGAGATTTTTTTTTTTTAGATATAGGACTAAGTGAATTAAATGAAATATCAATGTGGTGAAGGTAAACAGAGCGCATCTTTCGATAGCTCAATCTTAGTTCAAAAGACTCAATTATTCTCATTGATGAGATAGAAAATGGAAATTCATTACTCAGTAATCAAAGATATGATCAACGCTTTGATAGAAGCAGCAAAAACCAATAATAATCAAATATTTACAACAACGCACAGCTTCATGATGTAATATGTGCGATAAACGAATTAGATGAAAAAGAAAGATATATCTTACATAAGACTGGGAAGAGACAAGGAATCTCAAAAACCTACAGCAATGCAATTTAACATGGATGATTTTTCTTTTCAGTTGAAAATGGCTGGGAGGTGAGATAAATGAAACCGAGAAAAATAAATGATTATAAAAAGTCATTTTTCGTTGAGGGTGATGATGATTTCACTTCCTTTTGCAATCTACTTGAAATAGAAGGAATTAATGATGTTTATGTTGAAAAAATAAATGGAAAGACAAAAACAAACAAACCCTTAGAGCATTTAAAAGCATAGAGTCTTTTAATGAAAAAGAAAGTATATTCTTAATCATCGATGCCGACGAATCGTTTTCTGACACGGAAAGATCGATAATTTCAACATTAAATGAGCTTAACATTTCATCACCAAGCTCGCATAATGGGAAAATAGCCATTAACGGAAGCACAAAAATATCTTTCTTTATCATGCCAGGAAAAAACAAGAATAGCGCAATAGAAGATCTAATCATTGCTCACGCGTGTAAAAAGAAGAGGTGTTTAGATATAGACGATCTATTCAATAAAATAAAAGAACAAGAATCTATTATTACATCCTTAGATCTGGAACAACACCCAAATAATGAAAGAAAGCAAAGTTCAAGTTTACCTTAGTTGTAATAAGGAATCAGATTCTAGAATAGGCATATCAATGAAGAACAAAACCATTGATACTGACAGTGAAGCTGCTTCAGTGAGATAAAAATTTATATCAAAAATATGAAACAACTCCACCTACAAAATCATAGCGCAATGACTAAAGACAATTATAAAATTTAACATAATGCTGTAATTGTACGCACCGCTGAAACGCGCTGAACGCGATTCTGACGCAGACACCGCAAAAGAGATGTTTTACCCAGGAAAACGGGAAGGATGCGTCAGGATCGTTTTCAACTCCTTTCATAGCTATGCATGAAAGCGAATGGTGATCACTTTGGGAATTTACGGTGTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCGGGAAGCTAATCTGCAAGTCTGGATAACAGGGCACGGTGATACTCCGTAATAGCGATCCAGCACCTCCGCATACTCCCTGTCCCCGACACGCTTGCCGTCGATAAAGTTTTCTGTAACGCCCCCAGTCTCATAACTTCTTTCCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTACCGAGAGCTGCCGCCCGTAAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCTTTTCTGATTTCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATAGCCCGCCTGCGCGTATTACTTCCACTTCGTTTTGTCATAAAACATGGCTCCGTATCTGACATGGGTGTCGGAGGCAAAGCCTGACCAGGGCAATTGTAATAGCGTGCATGTATGCGCGGTATAGCAATTACATCCTGTCCTGTCAACAAGCTCGGATTACCGACAAAGGCACGGCAGTTTTGGCAGTGACGGTGTTTGTCTGACCAGAAATGCCGTCAAAAAAGCCAAGCGGCAGAATAACGGCAACAAAACAGTCGAAAAGTGGTACGCGATATAATCACACAACGCAGATGACAGACAGAACAGGAGAAAACGAAAAGATGAACAAGCAGCAAGCCGTACTCAACATGGCGGGATTCATAAAAGTCAGAGCCTGACGCTGCTCAAAAAAACTGGACACGCGATGCTGACGAACGAAAGGCTGCCATGTGTGAGAAGCTGCACGAACTCGCAGAAGAACTCCAGAACAGCATCAGACACGCTTTGAAGTAGAAAATGGCACAGAGAGATAACGCTCAGGCTGTCTCTTATACACATCTGACGCTGCCGACGACAGAGTGCGCGCGCAGCGGTACGTAACC 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-GAGCTTAACATTTCATCACCAAGCTCGCATAATGAAATAGCCATTAACGGAAGCACAAAAATATCTTTCTTTATCATGCCAGGAAAAACAAAATGGCGCAATAGAAGATCTAATCATTGCTCACACTTTGATATAAGAAGAGGTGTTTAGATATATAGACGATCTATTCAATAAAATAAAAGAACAGATAAGCCATCCTTAGATCCTGATTACGCTTACCCAAATAATGAAAAAGAAAGCAAAAGTTCAAGTTTACCTTAGTTGGCAATAAGAATCAGATTCTAGAATAAACCATATCAATGAAGAACAAAACCGTGATACCACTGACGATGACTTCCAGCCAGTGAGATAAAAGAATTTATATCAAAAATATGAAACAACTCCACCTACAAAATCATAGCGCAATGACTAAAGACAATTCATAAAATTTAACATAATGCTGTAATTGTACGCACATGAAACGCGCTGAACGCGATTCTGACGCAGACACCGCAA -+ -<05''+=BA478BE93<.0686487:1177>@8664/-4-7:BFFH><=AB?4;==>??@GC;4499B=FCB@=AB?CD<@6B>?1-.:AC3.'%->ADB@6&&240;<@?AD>B@FF053;/&%$$%(++;8733(9>'509A;@BD<>AEF>C1CDF@89:ECBKAAFJCDH@F=@AE(/74/&&-)$'&'(?56<5;A9C88:3449<>A>22<E>?@CE<9AD@BA?D4%19975@FF0):@CD131CF;2DDF6*9BB0	:()426,6-6,5145977:5*+&'))')+,;=8..D136@EFFA>,$6768-,+5:5DD;9>9>-$+-%*+$*509?EC?C;FOO2*4;AELGK=7AJMKMB9;78;D07''@B6<BBAFFEILL;15)/,0<AFFF7?C<<HNB6ACDBB3'-0?@0A?B.;?A>A@CCHCGAAHJFK=77C6:)0$%&(9941+49:88@<32436;A2;/.','(0.43547?? 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-CCGGTATGCTTCGTTCGGTTACGTATTGCTGCGCGCGCACTCTCTGTCGTCGGCAGCGTCAGATGTATAAGAGACAGCTTTGAAGTAGAAAATAGCACAGAGAAGATAACGCTCAGGACAGGATGCCGAACGGCACAACAGAGTAAGGAGAAAATGTCACATAAGGCGCTCTTCCGCTTCCTCGCTCACTTTGACTCGCTACGCTCGGTCGTTCGACTGCGGCGAGCAGTGTCAGCTCACTCAAAAAAGCGGTAATACGGTTATCCACAGAATCGGGGGATAAAGTCGGAAAGAACATGTGAGCAAAAGCAAAGCACCGGAGAAACCAGCGCCTGCGGGCGATTTTTCCATAGGCTCCGCCCCCTGACGAAGCACATCCGCAAAAATCGACGCTCAAGCCAGAGGTGGCGAAACCCGACAGGACTATAGCAAAGATACCAGGTGTTTCCCCCTGGAGGAAGCTCCTCGTGCGCTCTCCTGTTTCCGACCTGCCGCTTACCGGATACCGCAATCCGCCCTTTCTCCCTTCGGGAAGCGTGGCGCTCTCATAGCTCACGCTGCGCGGGTGGCATCTCCCGTTCGGTGTGGTCGTTCGCTCAAGCTGGGCTGTGCACGAACCCCCGTTCAGCCCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGGGTCCAGCCCGGTAAGACACGACAAAGCGCCACTGGCAGCAGCCATTGGTAAAGTCGATGTGCGAGGTTCAAGAGAGTACTTGAAGTGATGGCCTGACTACAGCTACACTGAAAGGACAGTTTTGGTGACTCGTCTCGCACAGAACAGTTACCTGGTTAAGCAGTTCTGGCTGGCTCAACCTTCGATCAAACCACCTCCCCAGGTGGTTTTTCGTTTTCAGTTTAGGAGATTACGACAGAACACAATAATCACAAGAAGAAACTCCGACAAACTGGTTAAAATCAATCAAACAGGACTATAAAGTAATATTATTTTGATTATACTTCTAGAGAAAAGAAACAGTGGCATAGTGATGCATAAATAAACACATTATTACTATGTAAACGTAAACAGAAATGGAGAGCAAAGTTTAAACATGATAAAGATATCCATAAGGAAATTTTAAGTGTTTCGAGCATAACTCTCAAACAACTAAACACTTAATGTAATATCCGGAAAAAACAACTTTGGGAGAAAACATCGATGTTAGACGCGATATTTTCATTTTATGACGTAAAAAACCCAGCAGCTCTGTTAAAAGTAAAAAAGCTTTAGAAATGAAGCATCTCTCTTTTAAATAAGAAAACTCATTTTGGGGATAGCTATTTTTTATAACATGGACACATCAAAGAAATATCCATAACAATAATGAGATGAAAGGTCAGAAGTAACACAAAAATACTCAACGATAGATAACACACAAAATTGAGATAAAACAATGGATCCACTAAATGTTAGTCAATATTATAAACACCCTCATTGCGACAAACCTCAATACTCAGAAGAATATTTTATTAGTTAAGATAGTGATTGCAGGTACGGAGGGAACTAGAAATTAGTTATATAAATATTTAAGCAAAAGAATAAATGAATAAGAATAAAAAACCACAAAAGGATTATTTATGATTCAAAACCGCGAGGTAGTAGCCACGTCAAGGCATAGACAGAGGCAACGATAAAAAACGTATCAAAACTACTAACACAAAAAGAAAAGATGGAAATAATAGGCAACCTAAAAGAATAGATAATAGAATTAACGATATTGCAATAATAGCAACAGATCAAAACAAAGAGATTTTAGATATAGGACTAAGTAAGTTAAGTAAATATCAGTACTTGAGTGAAGGAGTAAGCAGAGCGCTGTCTTTCATTAGCTCAATCTTAGTTCAAAAAGACTCAGTATTCATTGATGTAAGGATAGAAATGGAAATTCATTACTCAGTAATCAAAGATATAATCAACGCTTTGATAGAAGCAGCAAAAAACCAATAATAATCAAATATTTACAACAACACGCAGCCATGATGTAATATGTGCGATAAACGAATTAGATGAAAAAAGAAAAGATATATCTTACATAAGACTGGGGAAGAGACAAGGAATCTCAAAAACCTACAACAATGCAATTTAACATGGATAATTTTTTTTTTTTTTTTCTTTTCAGTTGAAAATGGCTGGGAGGTGAGATAAGTGAAACCGAGAAAAATAAATGATTATAAAAAAGTCATTTTCGTTGAGGGTGATGATGATTTTCACTTCCTTTGCAATCTACTTGAAATAGAAGGAATTAATGATGTTTATGTTGAAAAAATAAATGGAAAGACAAAACTAAAACAAACCCTTAGAGCATTTAAACATATAGAGTCTTTTTAATGAAAAAGAAAGTATATTCTTAATCATCGATGCCGACGAATCGTTTTCTGACACGGAAAGATCGATAATTTCAACATTAAATGGAGCTTAACGTTTCATCACCAAGCTCGCATAATGGAAATATGCATTAACGGAAGCACAAAATATCTTTCTTTATCATGCCAGGAAAAAACAAGAATGGCGCAATAGAAGATCTAATCATTGCTCGCGTGTAAGAAGAGGTGTTTAGATATATAGACGATCTATTCAATAAAATAAAGAACAAGAATCTATTATTACATCCCATAGATCCTGATTACGCTTACCCAAATAATGAAAAAGAAAGCAAAGTTTCAGTTTACCTTAGTTGTAATAAGGAATCAGATTCTAGAATAGGCATATCAATGAAGAACAAAACCATTGATACTGACGATGACACAGCTTCAGTGAGATAAAGAATTTATATCAAAATATATGAAACAACTCCACCTACAAAATCATAGCGCAATGACTAAAGACAATTATAAAATTTAACATAATGCTGTAATTGTACGCACCGCTGAAACGCGCTGAACGCGATTCTGACGCAGACACCGCAAAAGAGATGTTTTACGGGAAAACAGGAAGGATGCGTCAGGATCGTTTCAGCTCGCTGCATAACTATGCATGAAAGCGAATGGTGATCACTTTAAGGAACTTGGTGTTCATACCGTCTGTTTCGACAGTTTTCTCTCCGGGAAGCTAATCTGCCGCGGTCTGGATAACAGGGCACGGTGATGCTCCGTAATAGCGATCAGCACCTCCGCATACTCCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTCTGTAACGCCCCCCAGTCTCCACTTAACTTCTTTCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTGCGAGAGCTGCGCCCGTAAAAAACCGGGAAACAGTCTTGCCGCATTCAACAGCCCTTTTCACAGTTCCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATAGCCCGCCTGCGCGTATTACTTCCACTTCGTTTGTCATAAAACATGGCTCCGTATCTGACATGAGTGTCGGGGCAGAAGCCTGATGCGGGCAATTGTAATAGCGATGCATGTATGCGCGGTATAACAATTGCACATCCTGTCCCTGTCAGCAAGCTCGAATTACCGACAAAGGCCTGGCGAGTTTTTGGCAGTGACGGTGTTGTCTGACAGAAATGCCCGTCAAAAACCAAGCGGCAGAATAACGGCAACAAAACAGTCGAAAAGTGGTACGCGATATATAATCACACAACGCAGATGACAGACAGAACGGAGAAAACGAAAAGATGAACAAGCAGCAGCAAAGCGTACTCCAGCTTGGCGGGATTCGCCAAAAGTCAGGCCTGACGCTGCTCGAAAAACTGGACGCGCCGGTCACGCACCCACATTATCCTTTATTTCACGCGCACATTACACATTTACT 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-@312aea9f-74af-4bab-b77a-bc29c243e967 -CTGATATTACTTCGTTCGATTGCGTATTGCTGCGCGCACTCTCTCTGGTCTCGTGGGCTCGGAGATGTGTATAAGAGACGAGCTCCCTGTCCCCGACACGCTTGCCGTCGATAAAGGGATTTTTCTTAGCCCCCAGTCTCATAACTTCTTTCAGTACCCGATCATCAGTCAGTGAGTTACTTTCTTACCGAGAGCTGCCGCCATGCGCTAAACAGTCTTGCCGCATTCAGCAGCCCTTTCTGCATTTCCTGGTCACTGTACACCGTCAGACACGAACAGGGCGACGTAACCCGCCTGCGCGTATTACTTCGCTGATTTTGTCATAAAACATGGCTCCGTATCTGACATGGGTGTCGGGGCAAAGCCCTGACCAGAACATTGTAATAGCGTGCATGTATGCGCGATATAACAATTGCACATCCTCATCTTCATCAATGACTGAATTACCGACAAAGCGCGGCAGTTTTTGGCAGCGACAGTGTTGTCTGATAAATGCCCGTCAAAAACCAAGCGGCAGGCGTAACGGCAGCAAAACAGTCGAGAAGTGAGCGATATAATCACACAACGCAGATGACGAACCAGAACGGAGAAGAAAACGAAAAGATGAACAAGCAGCAGCAAGCCGTACTCAACATGGCAGGATTCATAAAAGTCAGAACCTGACGCTGCTCGAAAAACTGGACGCACCCGATGCTGACGAACAGGCTGCCATGTGTGAGAAGCTGCTACGAACTCGCGGAAGAACTCAGAACAGCATCCAGACACGCTTTGGAAGTAGAAAATAGCACAGAATAACGCTCAGGACAGGATGCCGAACGGCTGAAAGCAGAGCGTAAGGAGAAAATGTCACATAAAGGCGCTCTTCCCGCTTCCTCGCTCACTGACTCGCTACGCTCGGTCGTTCGACTGCGGCGAGCGGTGTCAACTCACTCAAGCGGTAATACGGTTATCCACAGAATCGGGGATAAAGTCGGAAGAACATGTGAGCAAAAGCAAAGCACCGGAGGAAGCCAGCGCCGCGGCGGTGCCATAGGCTCCGCCCCCTGACGAACATCACAAAAATCGACGCTCAAGCCAGAGGTGGCGAAACCCGGCAGGACTATAAAGATACCAGGTGTTTCACAGGCTCCTCGTGCGCTCTCCTGTTCCCGACCACCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTGCATAGCTCACGCTGGCGCCAGGTATCTCCGGTTCGGTGTAGGTCGTTCGGCTCAAAGCTGGGCTGTGGCGCTTGGGCTCCCCGTTCAGCCCGACCGCTGCGCCTTGTCCGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACAAGGCGCCACTGGCGGCAGCCATTGGTAAAAGTCGATTCTGCGAGAGGTTCAAGAGAGTACTTGAAGTGATGGCCTGACTACAGCTACACTGAAAGGACAGTTTTGGTGACTCGTCTCGCACAAAGACAGTTCACCTGGTTGAAAGCAGTTCCCCAACTGACAACCTTCAGATCAAACCACCTCCCCGGGTGGTTTTCGTTTTCAGTTTAGGGAGATTACGACCAGAACACAATAATCACAAGAAGAAACTCCGACAAACTGGTTAAAATCAATCCAAACAGGACTATAAAGTAATATTATTTTGATTATACTTCTAGAAAGAAACAGTATTGTAGTGATGCATAAATAAACACATTATTACTATGTAAACGTAAACAGAAATGGAGAGCAAGTTTAAACATGATAAAGATAATATCCACTTAAAATTTTAGAGTGTTTTCGAGGAGCATAACTCTCAAAACAGCTAAAAACACTTAATGTAATATCCGGAAAAAACAACTTTGGGGAAAGCCATCGATATTAGACGCGATATTTTCATTTTATGACGTAAAAAACCAGCAGCTCATTAAAAGTAAAAAGCTTTAGAAATGAAAACATCTCTTTTAAAATAAAGAAAACTCATTTTAGGATAGCTATTTTTTATAACATGGACACATCCAAAAATGTCATAACAATAAGAGATGAAAGAGATTGATAACACAAAATACTCAACGATAAGATAACACACAAAGTGAGATCAAGCGTGTCCCTCAATGTTGAGTCAATATTGTCATTGCCCCTCCATTGCGACAAACCCTCGGCTCTCAGGAAAAGGGAATGTTTTAATGATTAAGGTTAGTGAAACACAGAACGGAAAGAACCCACAGAAGAATTGATTACTATAAAATAACACAAAAGCACAAAGAAATAAACGAAATAAAACAAACTAAAAAGACAGCTATATGAATTCAAAGCTATGACATTAATAACAACCACATCCAAGAAACATAAACAAAGAAGCAACGATAAAAAACGTATCAAAACTGCTAACACAAAAGAAAGATGAAATAATAGGCAACCTAAAAGAATAGATAATAAATTAACGATATTGCAATAATAGCAACAGATCAAAACAAAGAGATTTTTTTAGATATAGGACTAAGTGAATTAAATGAAATATCAATGCTTGGTGAAGGAGTAAGCAGAGCGCTGTCAACACCATTAGCTCAATCTTAGTTCAAAAGACTCGAATTATTCTCATTGATGAGATAGAAAATGGAGATTCATTACTCAGTAATCAAAGATATGATCAACGCTTTGATAGAAGCAGCAAAAACCAATAATAATCAAATATTTACAAGCAACACACAGCCATGATGTAATATATTACGTGAAGCAGATTAGATGAAAAAGAAAAGATATATCTTACATAGGAGGCTGGGAAGAGACAAAGGAATGTCAAAAACCTACAGCAATGCAATTTAACATGGATGATTTTCTTTTCCAGTTGAAAATGGCTGGGAGGTGAGATAAATGAAACCGAGAAAAGAATAATGATTATAAAAAGTCATTTTTCGTTGAGGGGTGATGATGATTTTTCACTTCCTTTGCAATCTACTTGAAATAGAAGAATTAATGATGTTTATGTTGAAAAAATAAATGGAAAGACAAAACTAAAACAAACCCTTAGGCATTTTAAAGCATAGAGTCTTTTAATGAAGAAGAAAGTATATTCTTAATCATCGATGCCGACGAATCGTTTTCTGACACGGAAAGATCGATAATTTCAACATTAAATGAGCTTAACATTTTACCATCACCAAGCTCGCATAATGGAAATAGCCATTAACGGAAGCACAAGAAATATCTTTCTTTATCATGCCAGGAAAAAACAAAGAATGGCGCAATAGAATCTAATCATTGCTCCCGCGTGTAAGAAGGGTGTTTAGATATATAGACGATCTATTCAATAAAATAAAGAACAAGAATCTATTATTACATCCTTAGATCCTGATTACATTTTCCCAAGCCGTGAAAAGCAAAAGTTCAAGTTTACCTTGATTTGTAATAAGGAATCAGATTCTAGAATAGGCATATCAATGAAGAACAAACCATTGATACTGACGATGACTAGCTTCAGTGAGATAAAAGAATTTATATCAAAAATATGAAACAACTCCACCTACAAAATCATTTAGCGCAATGACTAAAGACAATTGCAAAATTTAACATAATGCTGTAATTGTACGCACCGCTAAAAACGCTGAACGCGATTCTGACGCAGACACCGCAAGAGATGGCTTTACCCCGGGAAAACGGAAGATCACGTCAGGATCGTTTCAGCTCGCTGCATAGCTATGCATGAAAGCGAATGGTGATCACTTTGGGAGCTTACGGTGTTCATGCGTCTGTTTTCGACAGTTTTCTCTCCGGGAAGCTAATCTGCCATAAGTCTGGATAACGGGGCACGGTGATGCTCATCATCAGCGGTCAGCACCTCCGCGCCTCCCTGTCCCTGTCTCTTATACACATCTCCGGAGCCCACGAGACCAGAGTGCGCGCGCAGCAGTATTGCGTAACT 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-TGATGCGCTTCGTTCAGTTACGTATTGCTGCGCGCACTCTCTGTCGTCGGCAGCGTCAGATTATAAGGGCAAGGAAGAGAATAAGGAAATCAGAAAAAGACTTGCTAGATGCGGCAGACCGTTTCCGGTTTTTGGCAGCTCTCGGTAAAAGTTAACTCACTGACTGATGATCGAATTACTGAAAGTTGTAAGAGCTGAGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGAATGGCGGAGGTGCTGATCGCTATTACCAGGGTATCACCGTGCCTGTTATCAGACTTGCCAGATTGGCTTCCCGGAGAGAAAACTGGCTTATCAGCAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCGTTATAGCTATCGGCAGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTCCCGGGTAAAACATCTCTTTTTGCCCAGTGTCGTCCAGAATCGCGCGTTCAGCGCGTTTTTCAGCGGTGCGGTGTTTACGGCATTATATTAAATTTTATAATTGTCTTTAGTCATTTGCGCTATGATTTGTAGAGGTGGAGTTGTTTCGTATTTTTGATATAAATTCTTTTATCTCACTGAAGCGGTCATCGTCAGTATCAATGGTTTTGTTCTTCATTGATAGCACCTATTCTAGAATCTGATTCCTTATTACAACTAGGTAAACTTGAACTTTTGCTTTCTTTTCATTATTTGGGTAAAGCACTTAATCAGGATCTAAGGATATGTTAATAATAGATTCTTGTTCTTTATTTTATTGAATGATCGTCTATATATCAAACACCTCTGCTTACACGCGTGAGCAATGGTTGAATCTTCTATTGCGCCATTCTTGTTTTTCTGTGATAAGAAGATATTTTGTGCTTCCGTTAATGAAAAGCTGTTTCATTTATGCGAGCTTGGTGATGAAATGTTAAGCTCATTTAATGTTGAGTATCGAATCTTTCCGTGTCAGAAAAACGATTCGTCGGCATCGATGATTAAGAATATGCTTTCTTTTTCATTAAAAGACTCTATGCTTTTAAATGCTCTAAGGGTTTGTTTTAGTTTTGTCTTTCCATTTATTTTTCAACATAAGCATCATTAATTCCTTCTATTTCAAGTAGATTGCAAAGGAAGTGAAAATCATCCATCACCCTCAACGAAAATGACTTTTTATAATCATTTATTTTCTCGGTTTTCATTTATCTCACACTTGACCATTTTCAACTGAAAAGAAAAATCATCCATGTTAAATTACATTGCTGTGAGTTTTGAGATTCCCTTGTCTCTTTGATCTTATGTAAGATATATCTTTTCTTTTTTTATCTAATTCGTTTATCGCACATATTACATCATGGCTGTGTGTTGTTGTAAATGTTTGTTATTATTGGTTTTTGCTGCTTCTATCAAAGCGTTGATCATATCTTTGATTACTGATAATGATTCACATTTTCTATCTCATCAATGCAAGTAATTGGAGTCTTTTTGAACTAAGATTGAGCTAATGAAAGACAGCCTTTCTGCTTACTCCTTCACCAAGCATTGATATTTCATTTAATTCATAGTCCTATATCTAAAAAATCTCTTTGTTTGATCTGTTGCTATTATTGCAATATCGTTAATTCTATTATCTATTCTTTTTAGGTTGCCTATTATTTCATCTTTTCTTTTTGTGTTAGTAGTTTTGATACGTTTTTTTATCGTTGCTTCTTTATTGTTTATGTTTCTTGATGTGGTTATTATCGCTGCGGTTTGAATTCATATAGCTTACCTTTTTTAGTTTGTTTTTATTTCTCGTTTATTTCTTGTACTTTTTGTATTTATTTTATAGTAATCAATGTGAATTCTTCTGGGGGGTTCTTGCGTTCACATGTTTCTACTAACCTTAATCATTAAAACATTTCCCGCACTAACCCAGCCGAGGTTTGTCGCAATGGGGTGATTGATGTTCGATAATGACAACGTTGCTTGTCACGGCTGGACTGTGTATTATCCATCGTTGAGTATTTTTGTGTTACTTCTGACCTTTCATCTACTTATTGTTATATGGACATTTCTTTGGATGTGTCCATGTTATAAAAATAACTATCCCCAAAGTGAGTTTTGCTATTTAAAAGAGATGCTTCATTTCTAAAGCTTTTTACTTACAACAGAGCTGCTGGGTTTTACGTCATAAATGAAAATATCGCGAAGCTCCTATTATCGATGTTTTCCCAAAGAGTTGTTTTCCGGATATTACATTGGTGTTTTTAGTTGTTGAGTTATGCTCTCGAAACACTTAAAATTTTAAGTGGATATCTTTTATCATGTTTAACTGCTCTCATTTCTATTTACGTTTATAGTAATATGTGTTTATTTATGCATCACTATACCACTGTTTTCTTTTCTGATATAATCAAAATAATATTACTTTATAGTCCTGTTTGGTTGATTTTAGCAGTTTGTCAGGTTTCTTCTTGTGATTATTGTGTTCTGAGTCATGTCCTAAACTGAAAACAGAAAAACCACCTGGGGAGGTGGTTTGATCGGGGTAGTCAGTTGGGGAACTGCTTAACCAGGTAACTGTCGAGACGAAGGTCACCAAAACTGTCCTTTCCACAGTGTAGCTGTAGTCAGGCCATCGCTTTAAGTACTCTCTTGAACCTCTCGCACATCGAAGCTTTTACCAATGGCTGCTGCAGTGGCGCTTTGTCGTGTCTTACCGGGTTGGACTCAGAGACGATAGTTACCGGATAAGACGCAGCGGTCGGGCGAACAGGGGGTTCGTGCACACAGCCCAGCTGGAGCGAACGACCTACACCGAACCGAGATACCTACAGCGTGACTGTAAGAAAGCGCCACGCTTCCCAGAGGGAGAAAGGCACGGACAGACATCCGGTAAGCGGCAGAGGTCGGAACAGGAGAGCGCATACGAGGGAGCTTCGGGGAAACACCTGGTATCTTTATAGTCCCATCCCGGTTTCGCCACCTCTGGCGAGCGTCGATTTTGTGATGCTCGTCAGGGCAGACGGAAACTCTGGCGCTGGCTATCGGTGCTTTGCTTTTGCTCCTGCTGCTATCCCCGATTCTATGGATGACCGGCAGCCGCTTTTGGTGAGCTGACACCGCTCGCCGCAGTCGAACGACCGAGCGTAGCGAGTCAGTGAGCAGGAAGCTGCTATGTGACATTTTCTCATTACGCTCTGTTGTGCCGTTCGGCATCTGTCCTGAGCGTTATCTCTCTGTGCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGCTTCTGCGAGTTCGTGCAGCTTCTCATGGCAGCCTGTTCGTCAGCATCAGGTACGTCAGTTTTCGAGCAGCGTCAGGCTCTGACTTTTATCATGTTGAGGTGGCTTGCTGCTGCTGTTCATCTTTCGTTTCTCCGTTCTGTCATCATCTCGTTGTGTGATTATATCGCACATTACCACTTTTCGACATTTTGCTGCCGTTATTTGCATTGGTAGTGTGGCGGCGTGCCGCTTGGCTTTTTGACGGGCATCGAACACTGTCACTGCCAAAAACTGCAAGTGCCTTTGTCAGTGGTCGAGCTTGCTGACAGGACGAGTGTCTGGTGTTATACCGCGCATACATGCGCAGCTATTCACAATTGCCCTGAATGAGGCGACACCCCATGTCTGGAGGCCATGTTTTATGACAAAACGAAGTGGAAGTAATACGCGCAGGCGGGCTATCAGTGTTCGTCGGCGGCAGAAGAAGAAGACGGGAAATCAGAAAAGACTTTGAATGCGGCAGACCGTTTCCGGTTTTACGGGCGGCAGCTCTCTGATAAGTTAACTCACTGACTGATGATCGGGTACTGAAAAAGTTATGAGACTGGGGGCGTTACAGAAAAGCTCTTTATCGACGGCAAGCGTGTCGGGGACGGGAGTATGCGAAGGTGCTACGATCGCTATTACGGAGTATCACCTGTCTCTTATACACATCTCCGAGCCACGAGACCAGAGTGCGCGCGCAGCAATTACCCGTAACT 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-@9c48bc3b-5d8c-47bc-96aa-9d291f376169 -GAATCGCGTTCAGCGCGTTTCAGCGGTGCATGCAATTACAGCATTATGTTAAATTTTATAATTGTCGCTAATTCATTACTATGATTTTGTAGGTGGAGTTGTTTCATATTTTTTGATATAAATTCTTTTATCTCACTGAAGCAGACATCGTCAGTATCAATGGTTTTGTTCTTCATTGATGTACTGTTCTAGAATCTGATTCCTTATTACAACTAAAGGTAAACTTGAACTTTTGCTGCCAGTATTTGGGTAGCGTAATCAGGATCTAAAGGATGTAATAATAGATTCTTGTTCTTTTTATTTTGTTGAATAGATCGTCTATATATCTAAACACCTCTTTCTTACACGCGTGAGCAATGGTTAGATCTTCTATTGCGCCATTCTTATTTTTCCTGGCATGATAAAGAAGATATTTTTGTGCTTCCGTTAATAAACTATTTCATTATGCGACTTGGTGATGAAATGTTAAAGCTCATTTAATGTTGAAATTATCGATCTTTCCGTGTCAGAAAGCTGATTCAGTGGCATCGATGATTAAGAATATACTTTCTTTTTCATTAAGACTCTATGCTTTAAATGCTCTAAGGGTTTGTTTAGTTTGTCTTTCCATTTATTTTTTCAACATAAACACATCGTATTTCGCTATTTCAGTAGATTGCAAAGTGAAATCATCATCACCTCAACGAAAATGACTTTTTATAATCATTTATTTTTCTCAGTTTCATTCATCTCACACTCCCAGCCATTTCCAACTGAAAAGAAAAATCATCCATGTTAAATTGCATTGCTGTAGGT -+ 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-TGTGTTGTACTTCGTTCAGTTACGTATTGCTGCGCGCGCCTCTCTGGTCTCGTGGGCTCGGAGATGTGTATAAGAGACAGCGTTAGGGGTGATGATGATTTTCACTTCCTTTGCAATCTACTTGAAATAGAAGAATTAATGATGTTTATGTTGAAAAAAATAAATGGAAAGACAAAACTAAAACAAACCATGACATTTAAAAACGCGAGTCACAATGAAAAGAAAGTATTCTTAATCATCGATGCCGACGAATCGTTTTCTGACACGGAAAGATCGATAAATTTCAACGATAAATAGGCTTAACATTTCATCACCAAGCTCGCATAATGGAAATAGCCATTAACGGAAGCACAAAATATCTTTCTTTATCATGCCGGAAAAAACAAGAATGGCGCAATAGAATCTAATCATTGCTCACGCGTATCAGAGAAGAGGTGTTTAGATATATAGACGATCTATTCAATAAAATAAAAGAACAAGAATATTATTACATCCTTAGATCTGATTACGTTTACCCAAGTAGTGAAGAAAGCAAAGTTCAAGTTTACCTTAGTTGTAATAAGGAATCAGATTCTAGAATGAGCATATCAATGAAGAACAAAACCATTGATACTGACATTATTCTTCAGTGAATAAAAGAATTTATATCAAAAATATGAAACAACTCCACCTACAAAATCATAGCGCAATGACTAAGAAACAATTATAAAATTTAACATAATGCTGTAATTGTACGCACCGCTAGAAACCGCGCTGAACGCGATTCACCGGCGCAGGCCGCAAAGAGATGTATTTACAGGAAAACAAGGAAGGATGCGTCAGGATCGTTTTCAGCTCGCTGTTTATCGTATGCATGAAAGCGAATGGTGATCGCACAGGGCTTTGGTGTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCGGGAAGCTAATCTGCCATAAGTCTGGATAACAGGGCACGGTGATACTCCGTAATAGCGATCAAACATCACATACCACTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTCTGTAGCGCCCCCAGTCTGCCATAACTTCTTTCAGTACCCGATCATCAGTCGGTGAGTTAACTTTCTTACCGAGAGCTGCCGCCCGTAAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCTTTTTCTGATTCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATAGCCCGCCTGCGCGTATTACTTCCTTCGTTTTTGTCATAAAACATGGCTCCGTATCTGACATAGGTGTCAGGGCAAAGCCTGACCTGGAACAGTGTAATAGCGTGCATGTATGCGCCAGGTATAACAATTTGCATCCTGTCCTGTCAACAAGCTCGGAGTACCGACAAAGGCACGGCAGTTTTTGGCGAGTAACCAGTGTTAATCTGACAAGAAGAGCTGCCGTGCGGTACGGCCGGTGAATTCAGCTTGCTGACAGAACAGGAGATGTCTGGTTGTTATACCGCGCATGCATGCGCGCTGGCCACGGTTGCCTGGTCGAGACTGCCCCGACACCGTGTTGTGACGGGTGAAATACGCGCGAGGCGACATCGTCGCC 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-CGGTGTACTTCGTTCAGTTACGTATTGCTGCGCACTTTGCGCACTGCACTCTCTGTATAAATATTCAGCGTCAGATGTCACAGAGACAGGATCTAAGGATGTAATAATGAATTCTTGTTCTTTTATTTTGATGAATAGATCGTCTATATATCTAAACACCTCTTTCTTACGCGTGAGCAATGATTAGATCTTCTATTGCGCCATTCTTGTTTTCCTAACGCATGATAAGAAGAAAGATATTTTGTGCTTCCGTTAATGGCTATTTCATTGCTGAGCTTGGTGATGAAGGTAATTACTCATTTAATGTTAAAATTATCGATCTTTCCGTCAGAAAACGATTCACGTCAACATCGATGATTAAAGACTTATCTTTCTTTTCATTAAAAGACTCTATGCTTTTAAATACTCTAAGGGTTTGTTTTAGTTTTGTCTTTCCATTTATTTTTCCAACATAAACATCATTAATTTATTCTATTTCAAGTAGATTTTAAAGGAAGTGAAAATCATCATCACCCTCAACGAAATGACTTTTTTTATAATCATTTATTTTTTCTCGGTTTCATTTATCTCACCTCCCAATACATTTCAGCATGAAAGAAAAATCATCCATGTTAAATTGCATTGCTGTGTAGGTTTTTGAGATTCCTTGTCCTCTTCCCAGTCTTATGTAAGATATATCTTTTCTTTTTTCATCTAATTCGTTATCGCACATATTACATCATGGCTGTGTGTTGTTGTAAATGTTGATTGTGTGGTTTTGCTGCTTCTATCAAGCGTTGATCATATCTTTGATTACTGAGTAATGAATTCCATTTTCTATCATCAATGAGAATAATTGAGTCTTTTGAACTAAGATTGAGCAATGAAGACAGCGCTCTGCTTACTCCTTCACCAAACATTGATATTTCATTTAATTCACTTAGTCTATATCTAAAAAATCTCTTTGTTTTGATCTGTTGCTATTGTGCAATATCGTTAATTCTAATATCTATTCTTTTTAGGTTGCCTATTATTTCATCTTTTCTTTTGTGTTAGTAGTTTTGATACGTTTTTATCTGCTTCTTTGTTTATGTTTCTTGATGTGGTTATTATCGCGCTGCGGTTTTGAATTCATATAGCTTACCTTTTTAGTTTGTTTTATTTCTCGTTTATTTCTTGTGCTCTTTGTGTTATTTTTATAGTAATCTATTCTTCTGGGTTCTTTTTCCGTTCTGTGTTTCACAACGCCAATCATTAAAAGCATTCCCGCCTGAGAGCCGAGGGTTTGTCACCAATGGAGGGTGGTGATCAATATTGACTCAACATTGGGGACACGCTTGATTCACTTGTGTTATCTATCGTTGAGGTATTTTTGTGTTACTTCTGACCTTTCATCTCTTATTGTTATGGACATTTCTTTGGATGTCCATGTTATAAAAATAGCTATCCAAAATGAGTTTTCTTTTTATTAAAAGTGTACTTCATTTCTAAAGCTTTTACTTTCAACAGAGCTGCTGGGGTTTTTACGTCATAAAATGAAAATATCGCGTCTAATATCGATGTTTTCCCAAAGTTGTTTTTACCAGGATATTACATTTAGTGTTTAGTTGTTTGAGTTATGCTCTCGAAACATAAAATTTTTAAGTGGATATCTTTTATCATGTTTAAACTTGCTCTCCATTTCTGTTTACGTTTACATAGTAATAATGTGTTTATCTATGCATCACTATGCCACTGTTTCTTTCTAGAGTATAATCAAAATAATATTACTTTATAGTCCTGTTTGGATTGATTTTAACCAGTTTGTCAGGTTTCTTCTTGTGATTATTGTGTTCACCAGAAAGGTCGTAATCTCCCTAAACTGAAAACGAAAAAAACCACACCTGGGGAGGGTGGTTTGATCCAGAAGGTTTAGTCAGTTGGGGAACTTGCTTCGACTGGGTAACTGTCTTCTTGTCCTTTCAGTGTAGCTGTAGTCCATCTCTTATACACATCTCCGACAAACTGGTTAAAATCAATCCAAACAGGACTTTATAAAGCGCAGTGCACTATTGATACGCCGTAACACATTATTACTATGTAAATAATTAAAATACAAAGTCTTCGAAGCATCTTCTTCCATGT 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-@4e07cefc-ddfe-479e-a9a2-4416fdf6b623 -CGTTGTACTTCGTTCAGTTACGTATTGCTGCGCGCACTCTCTGTCGTCGGCAGCGTCAGATGTGTATAAGAACCCAGCGTCTATATATCCGCTTACCTCTTTCTTACACGCGTGAGCAATGGTTAGATCTTCTATTGCGCCATTTCTTGTTTTTCTGGCATGATAGAAAGATATTTTTGTGCTTCCGTTAATGGCTATTTCATTATGCAGGCTTGGTGATGAAATGTTAAGCTCATTTAATGTTGAAATTATCGATATTTCCGTGTCAAGAAAACGATTCGTCGGCATCGATGATTAAGAATATACTTTCTTGCGTTAAAGACTCTATGCTTAAAATGCTCTATAAGGGTTTGTTTAGTTTTGTCTTTCATTTATTTTTTTCAACACTTAAACATCATTAATTCCTTCTATTTCCACGATAGATTGCAAAGGAAGTGAAAATCATCGCTCATCACCCTCCCAAGCCACACGGTGAAGACTTTTTATAATCAGTGTTTATTTTCTCGGTTTCATTTATCTCTCCAATGCATTTCAACTGAAAAAGAAAAATCATCCATGTTAAATTCACATTTGCACTGTAGGTTTTTGAGATTCCTTGTCTCTTCCCAGTCTTGTATGTAAGACCACTTATCTTTAGCATACCGCTGCTTTTCATCTAATTCGTTTATGTAGCACGCATATTTACAGTGTGGCTGTGTGTTGTAGCATTTGTAAATATTTGATTATTATTGGTTTTGCTGCCTATCAAGCGTTGATCCATATCTTTGATTACTGAGTAATGGTGACGTTGCTTTCACCACCATGTATCTCATAATGTCAATGGGAATATGGTGAGGTCTTTTGTGGACTGCCGCCCCGTAAGAATTGGCGGTGTTGTAGAGAGGGACAGAGAGAGAAAGAGCGCTCTGCTTGCCGCCGCTATAGCGATGATA -+ 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-AATCATCCATGTTAAATTGCATTGCTGTAGGTTTTTGAGATTCCTTGTCTCTTCCCAGTCTTATGTAAGATATATCTTTTCTTTTTCATCTAATTCGTTTATCGCACATATTGCATCATGGCTGTAATGTTGTTGTAAATGTTGATTATTATTGGTTTTTTACTGCTTCTATCAAAGCGTTGATCATATCTTTGATTACTGAGTAATGAATTCTTTCTATCTCATCAATGAGAATAATTGAGTCTTTTTGAGCTAAGATTGAGCTAATGAAAGACAGCACTCTGCTTACTCCTTCACCAAGCATTGATATTTCATTTAATTCACTTAGTCTATCTAAAAAATCTCTTTGTTTTGATCTGTTGCTATTATTTAGTATCGTTAATTCTATTATCTATTCTTTTAGGTTGCCTATTATTTCATCTTTTCTTTTGTGTTAGTAGTTTTGATACGTTTTTATCGTTGCTTCTTTATTTATGTTTCTTGATGTGGTTAATCGCTGCGGTTTTGAATTCATATAGCTTACCTTTTTTAGTTTGTTTTATTTCTCCGTTTATTTCTTGTGCTTTTTGTTATTTTATAGTAATCAATTCTTCTAGAGTTCTTTTTCCGTTCTGTGTTTCACTAACGCGTAGTAAGCTTTGTTCCCTTTTTCCTGAGAGCCGAGGGTTTGTCGCAATGGGGGTGTTTGATAATATTGACTCAGCATTGAGGACACATGATTCACTTTGTGTGTTATCTATCGTTGAGTATTTTGTGTTACTTCTGACCTTTCATCTCTTATTGTATGGACATTTCTTGGATGTGTCCATGTTATAAAAATAGCTATCCCAAATGAGTTTCTTTATTTAAAGAAGTCTTCATTTCACAAGAAGCTTTTCACTTTTAACAGAGCTGCTGGGTTTTACGTCATAAAATGAAAATATCGCGTCTAATATCGATGTTTTTCCCAAAGTTGTTTTTTCGGATATTACATTAAGTGTTTTAGTTGTTTGAGAGTTATGCTCAGAAACACTTGGAAATTTTAAGTGGATATCTTTTTATCATGTTTAAACTTGCTCTCCATTTCTGTTTACGTTTACATAGTAATAATG 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-GTTGTACTTCGTTCGGTTACGTATTGCTGCGCGCACTCTCTGTCGTCGGCAGCGTCAGATGTATTATAAAGTGAGTTGAGCTAATGAAGAGACAGCGCTCTGCTTCTCCTTCACCAAACATTGATGTTCATTTAATTAAACCCAGTCCCTATATCTAAAAAAATCTCTTTGTTTTGATCTGTTGCTATTATTGCAATATCGTTGAATTGTATCTAATCTTTTAGGTTGCCTATTATTTCATCTTTATTTTGTGTTAGTAGTTTTTGATACGTTTTTATCGTTGCTTCTTTGTTTATGTTTCTTGATGTGGTTATTATCGCTGCGGTTTTGAATTCATATAGCTTACCTTTTTAGTTTGTTTTATTTCTCCGTTTGTGCATGCTTTTTGCTTTATTTTTATAGTAATCAATTCTTCTGGGGAGTTCTTTTCCGTTCTGTGTTTCACTAACCTTAATCATTAAAACATTCCCCTTTTCCTGAGAACCGAGGTTTGTCGCAATGGAGAGTGTTTGATAATATTGACTCAACATTGGGGACACTTGATTCACTTTGTGTTATCTATCGTTGAGTATTTTTGTGTTACTTCTGACCTTTCATCTCTTATTGTTATGGACATTTCTTTGGATGTGTCCATGTTATAAAAATAGCTATCCCAAAATGAGTTTTCTTTATTTAGAAGTGCTTCATTTCTAAAGCTTTTACTTTTAACAGAGCTGCTGGGTTTTTACGTCATAAAATGAAAATATCGCGTCTAATATCCCGATGTTTTCCCAAAGTTGTTTTCGGATATTGTTAAGTGTTTTTGGTTGTTTGAGAGTTATGCTCTCGAAACACTTAAAATTTTAAGTGGATATCTTTTATCATGTTTAAACTTGCTCTCCATTTCTGTTTTAATTTACATAGTAATAATGTGTTTATTTATGCATCACTATACCACTGTTTCTTTTCTAGAAGTATAATCAAAATAATATTACTTTATAGTCCTGTTTGGATTGATTTTAACCAGTTTGTCAGGTTTCTTCTTGTGATTATTGTGTTCTGGTCATTAATCTCTAAACTGAAACAGAAAAAACACCTGGGGTGGACAGTCGAAGGATTAAGTCAGTTGAGAACTGCTTAGCCAGGTAACGTCTTGTGCGAGACGAGTCTTAAAACTGTCCTTTCCAGTGTAGCTGTAGTCAGGCCATCACTTCAAGTACTCTCTTGAACCTCTCGCACATCGACTTTTACCAATGGCTACCCCTGCCCGGTGGCGCTGTCGTGTCTTACCGGGTTGGACTCAAGACGATAGTTACCGGATAAGGCGCAGCAGTCCGGGCTGAACGGGGGGTTCATTGCACACAGCCCAGCTTAGACGAACGACTACACCGAACCGAGATACCTACAGCGTGAGCTATGAAAGCGCCACGCTTCCCGAAGGGAAGAAGGCGGACAGGTATCCGGTAAGCGGCAGAGTCGGAACAGGAGAGCGCACGAGGGAGCTTCAGGGGGAAACACCTGGTATCTTTTTATAGTCCTGTCGGGTTTCGCCACCTCTGGCTTGAGCGTCGATTTTGTGATGCTCGTCGGGGGAGCGGAGCCTATGGAAACGCCTGCGGCGCGCTGACTTCCTCCGGTGCTTTTGCTTTTGCTCACATGTTCTTTCCGACTTTATCCCCGATTCCACCATGGATAACCGTAATTACCGCTTTTGGGTGAGCTGACACCGCTCGCCGCAGTCGAACGACCGAGCGTAGCGAGTCAGTGAGCGAGGAGCGGAAGAGCGCCTTATGTGACATTTTCTCCACTTACGCTCTGTTGTGCCGTTCCGGCATCCTGTCCTGAGCGATTATCTCTCTGTGCTATTTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTGCGGCTTCTCACACATGGCAACCTGTTCGTCAGCATCAGGTGCGTCCAGTTTTCGAGCAGCGTCGGAAGTGACTTTTTATAGATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACCGCACCCCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTTGACGGGCATTTCTGTCAGGTGGAGCAACACTGTCACTGCAAAAAACTGCCGTGCGGTTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATATTCTGGTGTTATACCGCGCATACATGCGCTATTACAATTGCCCACCAATCGAGCTTGCCCCGACACCCATGTCAGATACGGAGCCATGTTTTTATGACAAAACGAAGTGGAAGTAATACGCGCAGGCGGGCTATCCCAGTCGCCCTGTTCGTCTGACGGCAGAAGAAGACCAGGAAATCAGAAAAGGGCTGCCAGATGCGGCAAGACCGTTTCGGTTTTTACGGGCGGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCGGGTACTGAAAGAAGTTATGAGACTGGGGAGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCAGGGGACAGGGAGTATGCGGAGGTGCCAGTCGCTATTACGGAGTATCACCGTGCCCTGTTATCCAGACTTATGGCAGATTAGCTTCCCGGAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCGTTGTTTCATGCATAGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCCGGGGTAAAACATCTCTTTTTGCGGTGTCTGCGTCAGAATCGCGTTCAGCGCGTTTCAGCCAGTGCGTACAATTACAGCGATATGTTAAAATTTTATAATTGTCTTTAGTCATTTGCTATGATTTTGTAGGTGGAGTTGTTTCATATTTTTGATATAAATTCTTTATCTCACTAAACAGTCATCGTCAGTATCAATGGTTTTGTTCTTCATTGATATGCCTATTCTAGAATCTGATTCCTTATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTCATTATTTGGGTAAAAGCGTAATCGGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTTATTTTATTGAATAGATCGTCTATATATCTAAACACCTCTTTCTTACACGCGTGAGCAATAGTTAGATCTTCTATTGCGCCATTCTTGTTTTTTCTAGCATGATAAAAGAAAGATATTTTGTGCTTCCGTTAATGGCTATTTCATTAGCCAAGGCTTGGTGATGAAATGTTAATCATTTAATGTTGAAATTATCGATCTTTCCGTGTCAGAAAACGATTCGTCGGCATCGATGATTAAGAATATACTTTCTTTTCATTAAAAGACTCTATGCTTTTAAATGCTCTAAGGGTTTGTTTTAGTTTTGTCTTTCATTTATTTTTCAACATAAACATCATTAATTCCTTCTATTTCAAGTAGATTGCAAAGGAAGTGAAAATCATCATCACCCTCAGCTTGAAAATGACTTTTTTATAATCATTTATTTTTCTCAGTTTCATTTATCTCACCTCCCAGCCATTTTCAACTGAAAAAGAAAAATCATCCATGTTAAATTGCATTGCTGTAGGTTTTTGAGATTCCTTATCTCTTCCCAGTCTTATATAAGATATATCTTTTCTTTTTCATCTAATTCGTTTATCGCACATATTACATCATGTGGCTGTGTTGTTGTAAATATTTGATTATTATTGGTTTTTGCTGCTTCTATCAAAGCGTTGATCATATCTTTGATTACTGAGTAATGAATTCCATTTTCTATCTCATCGAGAATAATTGAGTCTTTTTGAACTAAGATTGAGCTCTGTCTCTTATACACGGCCCTGACGCTGCCGACGACAGAGTGCGCGCAGCAGTACGTAAC 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