changeset 3:e86fcef8ed91 draft

"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/medaka commit e80b649094384fc6d7a8f917300db3550cc99a44"
author iuc
date Tue, 01 Sep 2020 03:08:24 -0400
parents d50c1d5b72ce
children 2308bc523659
files annotateVCF.py macros.xml test-data/annotate_vcf_test.pileup test-data/annotate_vcf_test.vcf test-data/annotated.vcf test-data/basecalls.fastq test-data/bwa-mem-mt-genome.fa.fai test-data/medaka_test.bam test-data/medaka_test.bam.bai test-data/medaka_test.hdf test-data/ref.fasta test-data/ref.fasta.fai test-data/variants.vcf.gz variant.xml
diffstat 14 files changed, 482 insertions(+), 549 deletions(-) [+]
line wrap: on
line diff
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/annotateVCF.py	Tue Sep 01 03:08:24 2020 -0400
@@ -0,0 +1,398 @@
+#!/usr/bin/env python3
+
+# Takes in VCF file and a samtools mpileup output file
+# Fills in annotation for the VCF file including AF, DP
+# SB, and DP4
+#
+# Usage statement:
+# python annotateVCF.py in_vcf.vcf in_mpileup.txt out_vcf.vcf
+#
+# Can generate in_mileup.txt with samtools mpileup (and can restrict which sites to generate pileups for with in_vcf.vcf)
+
+# 08/24/2020 - Nathan P. Roach, natproach@gmail.com
+
+import sys
+from math import isnan, log10
+
+from scipy.stats import fisher_exact
+
+
+def pval_to_phredqual(pval):
+    return int(round(-10. * log10(pval)))
+
+
+def parseSimpleSNPpileup(fields, ref_base, alt_base):
+    base_to_idx = {
+        'A': 0,
+        'a': 0,
+        'T': 1,
+        't': 1,
+        'C': 2,
+        'c': 2,
+        'G': 3,
+        'g': 3
+    }
+
+    base_to_idx_stranded = {
+        'A': 0,
+        'T': 1,
+        'C': 2,
+        'G': 3,
+        'a': 4,
+        't': 5,
+        'c': 6,
+        'g': 7
+    }
+    ref_base2 = fields[2]
+    counts = [0, 0, 0, 0]
+    stranded_counts = [0, 0, 0, 0, 0, 0, 0, 0]
+    ref_idx = base_to_idx[fields[2]]
+    dp = int(fields[3])
+    carrot_flag = False
+    ins_flag = False
+    ins_str = ""
+    ins_len = 0
+    insertion = ""
+    del_flag = False
+    del_str = ""
+    del_len = 0
+    deletion = ""
+    # dollar_flag = False
+    for base in fields[4]:
+        if carrot_flag:
+            carrot_flag = False
+            continue
+        if ins_len > 0:
+            insertion += base
+            ins_len -= 1
+            continue
+        if del_len > 0:
+            deletion += base
+            del_len -= 1
+            continue
+        if ins_flag:
+            if base.isdigit():
+                ins_str += base
+            else:
+                ins_len = int(ins_str) - 1
+                insertion = base
+                ins_flag = False
+        elif del_flag:
+            if base.isdigit():
+                del_str += base
+            else:
+                del_len = int(del_str) - 1
+                deletion = base
+                del_flag = False
+        else:
+            if base == '^':
+                carrot_flag = True
+                continue
+            elif base == '$':
+                continue
+            elif base == '+':
+                ins_flag = True
+            elif base == '-':
+                del_flag = True
+            elif base == '.':
+                counts[ref_idx] += 1
+                stranded_counts[base_to_idx_stranded[ref_base2]] += 1
+            elif base == ',':
+                counts[ref_idx] += 1
+                stranded_counts[base_to_idx_stranded[ref_base2.lower()]] += 1
+            elif base == 'N' or base == 'n':
+                continue
+            elif base == '*':
+                continue
+            else:
+                counts[base_to_idx[base]] += 1
+                stranded_counts[base_to_idx_stranded[base]] += 1
+    af = float(counts[base_to_idx[alt_base]]) / float(sum(counts))
+    if float(sum(stranded_counts[0:4])) == 0:
+        faf = float("nan")
+    else:
+        faf = float(stranded_counts[base_to_idx_stranded[alt_base]]) / float(sum(stranded_counts[0:4]))
+    if float(sum(stranded_counts[4:])) == 0:
+        raf = float("nan")
+    else:
+        raf = float(stranded_counts[base_to_idx_stranded[alt_base.lower()]]) / float(sum(stranded_counts[4:]))
+    dp4 = [stranded_counts[base_to_idx_stranded[ref_base]],
+           stranded_counts[base_to_idx_stranded[ref_base.lower()]],
+           stranded_counts[base_to_idx_stranded[alt_base]],
+           stranded_counts[base_to_idx_stranded[alt_base.lower()]]]
+    return (dp, af, faf, raf, dp4)
+
+
+def parseIndelPileup(fields, ref_base, alt_base):
+    counts = [0, 0, 0, 0, 0, 0, 0, 0, 0]  # indel ref match, indel fwd ref match, indel rev ref match, indel alt match, indel fwd alt match, indel rev alt match, other, other fwd, other rev
+    ref_base2 = fields[2]
+
+    carrot_flag = False
+    ins_flag = False
+    ins_str = ""
+    ins_len = 0
+    del_flag = False
+    del_str = ""
+    del_len = 0
+    first_iter = True
+    forward_flag = False
+    last_seq = ""
+    last_seq_code = 'b'
+    for base in fields[4]:
+        if ins_flag:
+            if base.isdigit():
+                ins_str += base
+            else:
+                ins_len = int(ins_str)
+                ins_flag = False
+        if del_flag:
+            if base.isdigit():
+                del_str += base
+            else:
+                del_len = int(del_str)
+                del_flag = False
+        if ins_len > 0:
+            last_seq += base
+            last_seq_code = 'i'
+            ins_len -= 1
+            continue
+        if del_len > 0:
+            last_seq += base
+            last_seq_code = 'd'
+            del_len -= 1
+            continue
+        if carrot_flag:
+            carrot_flag = False
+            continue
+        if base == '.' or base == ','\
+                or base == 'A' or base == 'a'\
+                or base == 'C' or base == 'c'\
+                or base == 'G' or base == 'g'\
+                or base == 'T' or base == 't'\
+                or base == 'N' or base == 'n'\
+                or base == '>' or base == '<'\
+                or base == '*' or base == '#':
+            if first_iter:
+                first_iter = False
+            else:
+                if last_seq_code == 'i':
+                    if last_seq.upper() == alt_base.upper():
+                        counts[3] += 1
+                        if forward_flag:
+                            counts[4] += 1
+                        else:
+                            counts[5] += 1
+                    else:
+                        counts[6] += 1
+                        if forward_flag:
+                            counts[7] += 1
+                        else:
+                            counts[8] += 1
+                elif last_seq_code == 'd':
+                    if last_seq.upper() == ref_base.upper():
+                        counts[3] += 1
+                        if forward_flag:
+                            counts[4] += 1
+                        else:
+                            counts[5] += 1
+                    else:
+                        counts[6] += 1
+                        if forward_flag:
+                            counts[7] += 1
+                        else:
+                            counts[8] += 1
+                elif last_seq_code == 'b':
+                    if last_seq.upper() == ref_base.upper():
+                        counts[0] += 1
+                        if forward_flag:
+                            counts[1] += 1
+                        else:
+                            counts[2] += 1
+                    elif last_seq.upper() == alt_base.upper():
+                        counts[3] += 1
+                        if forward_flag:
+                            counts[4] += 1
+                        else:
+                            counts[5] += 1
+                    else:
+                        counts[6] += 1
+                        if forward_flag:
+                            counts[7] += 1
+                        else:
+                            counts[8] += 1
+            if base == '.':
+                last_seq = ref_base2
+                forward_flag = True
+                last_seq_code = 'b'
+            elif base == ',':
+                last_seq = ref_base2
+                forward_flag = False
+                last_seq_code = 'b'
+            elif base == '>' or base == '<' or base == '*' or base == '#':
+                continue
+            else:
+                forward_flag = base.isupper()
+                last_seq = base.upper()
+                last_seq_code = 'b'
+        elif base == '+':
+            ins_flag = True
+            ins_str = ""
+        elif base == '-':
+            del_flag = True
+            del_str = ""
+        elif base == '^':
+            carrot_flag = True
+        elif base == '$':
+            continue
+        if first_iter:
+            first_iter = False
+
+    if last_seq_code == 'i':
+        if last_seq.upper() == alt_base.upper():
+            counts[3] += 1
+            if forward_flag:
+                counts[4] += 1
+            else:
+                counts[5] += 1
+        else:
+            counts[6] += 1
+            if forward_flag:
+                counts[7] += 1
+            else:
+                counts[8] += 1
+    elif last_seq_code == 'd':
+        if last_seq.upper() == ref_base.upper():
+            counts[3] += 1
+            if forward_flag:
+                counts[4] += 1
+            else:
+                counts[5] += 1
+        else:
+            counts[6] += 1
+            if forward_flag:
+                counts[7] += 1
+            else:
+                counts[8] += 1
+    elif last_seq_code == 'b':
+        if last_seq.upper() == ref_base.upper():
+            counts[0] += 1
+            if forward_flag:
+                counts[1] += 1
+            else:
+                counts[2] += 1
+        elif last_seq.upper() == alt_base.upper():
+            counts[3] += 1
+            if forward_flag:
+                counts[4] += 1
+            else:
+                counts[5] += 1
+        else:
+            counts[6] += 1
+            if forward_flag:
+                counts[7] += 1
+            else:
+                counts[8] += 1
+    dp = int(fields[3])
+    af = float(counts[3]) / float(sum([counts[0], counts[3], counts[6]]))
+    if sum([counts[1], counts[4], counts[7]]) == 0:
+        faf = float("nan")
+    else:
+        faf = float(counts[4]) / float(sum([counts[1], counts[4], counts[7]]))
+    if sum([counts[2], counts[5], counts[8]]) == 0:
+        raf = float("nan")
+    else:
+        raf = float(counts[5]) / float(sum([counts[2], counts[5], counts[8]]))
+    dp4 = [counts[1], counts[2], counts[4], counts[5]]
+    return (dp, af, faf, raf, dp4)
+
+
+def annotateVCF(in_vcf_filepath, in_mpileup_filepath, out_vcf_filepath):
+    in_vcf = open(in_vcf_filepath, 'r')
+    in_mpileup = open(in_mpileup_filepath, 'r')
+    out_vcf = open(out_vcf_filepath, 'w')
+
+    # First pass parsing of input vcf, output headerlines + new headerlines, add VCF sites we care about to to_examine (limits memory usage for sites that don't need annotation)
+    to_examine = {}
+    for line in in_vcf:
+        if line[0:2] == "##":
+            out_vcf.write(line)
+        elif line[0] == "#":
+            out_vcf.write("##annotateVCFVersion=0.1\n")
+            out_vcf.write("##INFO=<ID=DP,Number=1,Type=Integer,Description=\"Raw Depth\">\n")
+            out_vcf.write("##INFO=<ID=AF,Number=1,Type=Float,Description=\"Allele Frequency\">\n")
+            out_vcf.write("##INFO=<ID=FAF,Number=1,Type=Float,Description=\"Forward Allele Frequency\">\n")
+            out_vcf.write("##INFO=<ID=RAF,Number=1,Type=Float,Description=\"Reverse Allele Frequency\">\n")
+            out_vcf.write("##INFO=<ID=SB,Number=1,Type=Integer,Description=\"Phred-scaled strand bias at this position\">\n")
+            out_vcf.write("##INFO=<ID=DP4,Number=4,Type=Integer,Description=\"Counts for ref-forward bases, ref-reverse, alt-forward and alt-reverse bases\">\n")
+            out_vcf.write(line)
+        else:
+            fields = line.strip().split()
+            if fields[0] in to_examine:
+                to_examine[fields[0]][int(fields[1])] = (fields[3], fields[4])
+            else:
+                to_examine[fields[0]] = {int(fields[1]): (fields[3], fields[4])}
+    in_vcf.close()
+    data = {}
+
+    # Populate data dictionary, which relates chromosome and position to the following:
+    #  depth of coverage
+    #  allele frequency
+    #  forward strand allele frequency
+    #  reverse strand allele frequency
+    #  dp4 - depth of coverage of ref allele fwd strand, DOC of ref allele rev strand, DOC of alt allele fwd strand, DOC of alt allele rev strand
+    for line in in_mpileup:
+        fields = line.strip().split()
+        if fields[0] not in to_examine:
+            continue
+        if int(fields[1]) not in to_examine[fields[0]]:
+            continue
+        (ref_base, alt_base) = to_examine[fields[0]][int(fields[1])]
+        if len(ref_base.split(',')) > 1:  # Can't handle multiple ref alleles
+            continue
+        if len(alt_base.split(',')) > 1:  # Can't handle multiple alt alleles
+            continue
+        if len(ref_base) > 1 or len(alt_base) > 1:
+            if len(ref_base) > 1 and len(alt_base) > 1:  # Can't handle complex indels
+                continue
+            data[(fields[0], int(fields[1]))] = parseIndelPileup(fields, ref_base, alt_base)
+        if len(ref_base) == 1 and len(alt_base) == 1:
+            data[(fields[0], int(fields[1]))] = parseSimpleSNPpileup(fields, ref_base, alt_base)
+    in_mpileup.close()
+    # Reopen vcf, this time, skip header, annotate all the sites for which there is an entry in data dictionary
+    # (Sites without entries have either multiple ref or alt bases, or have complex indels. Not supported (for now), and not reported as a result)
+    in_vcf = open(in_vcf_filepath, 'r')
+    for line in in_vcf:
+        if line[0] == '#':
+            continue
+        fields = line.strip().split('\t')
+        if (fields[0], int(fields[1])) not in data:
+            continue
+        (dp, af, faf, raf, dp4) = data[(fields[0], int(fields[1]))]
+        dp2x2 = [[dp4[0], dp4[1]], [dp4[2], dp4[3]]]
+        _, p_val = fisher_exact(dp2x2)
+        sb = pval_to_phredqual(p_val)
+        if fields[7] == "":
+            info = []
+        else:
+            info = fields[7].split(';')
+        info.append("DP=%d" % (dp))
+        info.append("AF=%.6f" % (af))
+        if isnan(faf):
+            info.append("FAF=NaN")
+        else:
+            info.append("FAF=%.6f" % (faf))
+        if isnan(raf):
+            info.append("RAF=NaN")
+        else:
+            info.append("RAF=%.6f" % (raf))
+        info.append("SB=%d" % (sb))
+        info.append("DP4=%s" % (','.join([str(x) for x in dp4])))
+        new_info = ';'.join(info)
+        fields[7] = new_info
+        out_vcf.write("%s\n" % ("\t".join(fields)))
+    in_vcf.close()
+    out_vcf.close()
+
+
+if __name__ == "__main__":
+    annotateVCF(sys.argv[1], sys.argv[2], sys.argv[3])
--- a/macros.xml	Thu Jun 18 05:08:21 2020 -0400
+++ b/macros.xml	Tue Sep 01 03:08:24 2020 -0400
@@ -5,6 +5,7 @@
     <xml name="requirements">
         <requirements>
             <requirement type="package" version="@TOOL_VERSION@">medaka</requirement>
+            <requirement type="package" version="1.4.1">scipy</requirement>
         </requirements>
     </xml>
     <xml name="version_command">
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/annotate_vcf_test.pileup	Tue Sep 01 03:08:24 2020 -0400
@@ -0,0 +1,3 @@
+NC_045512.2	45	G	31	CCCCACCCCCCccccccccc,ccCCC*,+3ttccCC	~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
+NC_045512.2	685	A	75	.-9AAGTCATTT,-9aagtcattt,-9aagtcattt*.-9AAGTCATTT*G.-9AAGTCATTT.-9AAGTCATTT,-9aagtcattt*,-9aagtcattt,-9aagtcattt,-9aagtcattt,-9aagtcattt,,-9aagtcattt,-9aagtcattt,-9aagtcatttG.-9AAGTCATTT*,-9aagtcatttG.-9AAGTCATTT.-9AAGTCATTTG.-9AAGTCATTTG.-9AAGTCATTT.-9AAGTCATTT.-9AAGTCATTT.-9AAGTCATTT.-9AAGTCATTT*.-9AAGTCATTT*.-9AAGTCATTT.-9AAGTCATTT.-9AAGTCATTT.-9AAGTCATTT.-9AAGTCATTTG.-9AAGTCATTT.-9AAGTCATTT.-9AAGTCATTT.-9AAGTCATTT.-9AAGTCATTT.-9AAGTCATTT*,-9aagtcattt,-9aagtcattt*,-9aagtcattt,-9aagtcattt,-9aagtcattt,-9aagtcattt,-9aagtcattt,-9aagtcattt*,-4aagt,-9aagtcattt,-9aagtcattt**G,-9aagtcattt,-9aagtcattt,-9aagtcatttG,-9aagtcattt,-9aagtcattt*,-9aagtcattt*	~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
+NC_045512.2	1813	T	51	..-3AAA..-2AA..-1A*.-1A.-3AAA*..-1A..-1A.-2AA.-1A.-3AAA.-2AA.-2AA.-3AAA.,-1a,-1a,-6aaaaaa,,,-1a,,-2aa,-2aa,,-1a,-1a,*,-1a,-1a,+1a,-2aa,-1a,+1a,-1a,,-2aa.-3AAA,-1a.-2AA,-1a*,-2aa,-2aa	~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/annotate_vcf_test.vcf	Tue Sep 01 03:08:24 2020 -0400
@@ -0,0 +1,9 @@
+##fileformat=VCFv4.1
+##medaka_version=1.0.3
+##contig=<ID=NC_045512.2>
+##FORMAT=<ID=GT,Number=1,Type=String,Description="Medaka genotype.">
+##FORMAT=<ID=GQ,Number=1,Type=Integer,Description="Medaka genotype quality score">
+#CHROM	POS	ID	REF	ALT	QUAL	FILTER	INFO	FORMAT	SAMPLE
+NC_045512.2	45	.	G	C	46.359	PASS		GT:GQ	1:46
+NC_045512.2	685	.	AAAGTCATTT	A	260.487	PASS		GT:GQ	1:260
+NC_045512.2	1813	.	TA	T	11.034	PASS		GT:GQ	1:11
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/annotated.vcf	Tue Sep 01 03:08:24 2020 -0400
@@ -0,0 +1,16 @@
+##fileformat=VCFv4.1
+##medaka_version=1.0.3
+##contig=<ID=NC_045512.2>
+##FORMAT=<ID=GT,Number=1,Type=String,Description="Medaka genotype.">
+##FORMAT=<ID=GQ,Number=1,Type=Integer,Description="Medaka genotype quality score">
+##annotateVCFVersion=0.1
+##INFO=<ID=DP,Number=1,Type=Integer,Description="Raw Depth">
+##INFO=<ID=AF,Number=1,Type=Float,Description="Allele Frequency">
+##INFO=<ID=FAF,Number=1,Type=Float,Description="Forward Allele Frequency">
+##INFO=<ID=RAF,Number=1,Type=Float,Description="Reverse Allele Frequency">
+##INFO=<ID=SB,Number=1,Type=Integer,Description="Phred-scaled strand bias at this position">
+##INFO=<ID=DP4,Number=4,Type=Integer,Description="Counts for ref-forward bases, ref-reverse, alt-forward and alt-reverse bases">
+#CHROM	POS	ID	REF	ALT	QUAL	FILTER	INFO	FORMAT	SAMPLE
+NC_045512.2	45	.	G	C	46.359	PASS	DP=31;AF=0.900000;FAF=0.937500;RAF=0.857143;SB=6;DP4=0,2,15,12	GT:GQ	1:46
+NC_045512.2	685	.	AAAGTCATTT	A	260.487	PASS	DP=75;AF=0.880000;FAF=0.789474;RAF=0.972973;SB=0;DP4=0,0,30,36	GT:GQ	1:260
+NC_045512.2	1813	.	TA	T	11.034	PASS	DP=51;AF=0.607843;FAF=0.521739;RAF=0.678571;SB=0;DP4=0,0,12,19	GT:GQ	1:11
--- a/test-data/basecalls.fastq	Thu Jun 18 05:08:21 2020 -0400
+++ b/test-data/basecalls.fastq	Tue Sep 01 03:08:24 2020 -0400
@@ -498,519 +498,3 @@
 GTTGTACTTCGTTCGGTTACGTATTGCTGCGCGCGCACTCTCTGTCGTCAACGGCGTCAGATATTATTATAAGAGACAGCTCCTTCACCAAGCATTGATATTTCATTTAATTCGCCAGTCCTATATAAAAAAAATCTCTTTGTTTGATCTGTTGCTATTATTGCAATATCGTTAATTCTATTATCTATTCTTTTTAGGTTACCTATTATTTCATCTTTTCTTTTTGTGTTAGTAGTTTTGATACGTTTTATCGTTGCTTCTTCATTTATGTTTCTTGATGTGGTTATTATCGCTTGCGGTTTTGAATTCATATAGCTTACCTTTTTTAGTTTGTTTTATTTCTCCGTTTATTTCTTGTGCTTTTTTGTGTTATTTTTATAGTAATCAATTCTTCTGGGGGTTCTTTTTCCGTTCTGTGTTTCACTAACCTTAATCATTTAAAACATTTCCCCCCTTTCCTGAGAGCCGAGGGGTTTGTCGCAATGGAGGGTGTTTGATAATATTGACTCAACATTGGGGGACACGCTTGATTCTGTCTCTTATATACAATCTCCGAGCCCACGAGACCAGAGTGCGCGCAGCAATGCGTAACT
 +
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
-@f2a18031-a79d-4fd4-8200-836066a428c6
-GTGTGTATTACTTCGTTCAGTTACGTATTGCTGAAAAAGAAACAGTGGCATAGTGATGCATAAATAAACACATTATTACTATGTAAACGTAAACAGAAATGGAGAGCAAGTTTAAACATGATAAAGATATCCATAAAAAGAAATTTTAAAGTGTTTCGAGGAACATAACTCTCAAACAACTAAAAACACTTAATGTAATATCCGGAAAAAACAACTTTTGGGAAAACATCGATATTAGACTGGAAATATTTTCATTTATGACGTAAAAAAACCCAGCAGCTCTGTTAAAGTAGCTTTAGAAATGAAGCATCTCTTTTAAATAAAGCTCATTTGGGATAGCTATTTTTACAACATGGACACATCAAAGAAATATCCATAACAATAAGAGATGAAAGGTCAAGAAGTAACACAAAAATACTCAACGATAGATAACACCTAGAAAGTCTGAATCAAGCGTGTCCCTCAATGTTGAGTCAATATTATCAAACACCCCTCCATTTACGACAAACCCTCGGCTCTCAGGAAAAGGGAATGTTTTAATGATTAAGGTTAAGTGAAGCCACAGAACGGAAAAAGAACCCCCCAGAAGAATTGATTACTATAAAAATAACACAAAAAGCACAAGAAATAAACGGAGAAATAAACAAACCCCAAAGGTAAGCTATATGAATTCAAAACCGCAGCGATAATAACCACATCAAAAACATAAACAAAGAAGCAACGATAAAAAACGTATCCAAAACTACTAACACAAAGAAAAGATGAAATAATAGGCAACCTAAAAAGAATAGATAATAGAATTAACGATATTGCAATAATAGCAACAGATTAAACAAAGAGATTTTTAGATATAGGACCTGTCTCTTATACACATCTGACGCTGCCGACGACAGAGAGTGCGCGCGCAACAATACGTAAC
-+
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
-@435ec27b-52bf-4575-b4f5-fcb8892a768b
-CTATATCTAAAAAATCTCTTTGTTTTGAAGTCTGTTGCTATTATTACAATATCGTTAATTCTATTATCTATTCTTTTAGGTTGCCTATTGTTTCATCTTTTCTTTTTGTGTTAGTAGTTTTTGATACGTTTTTTTATCGTTGCTTCTTTGTTTATGTTTCTTGATGTAGATTTATTATCAACTGCGTTTTAGATTCGTATAAGCTTACCTTTTTAGTTTGTTTTATTTCTCCGTTTGTTTCTTATTGCTTTTGTGTTTTTATAGTAATCAATTCTTCTGGGGGTTCTTTTTCCGTTTCTGTGTTTCACTAACCCAATCATTAAAACATTCCCTTTTCCCCCTGAGAGCCGAGGGTTTGTCGCAATGGAGGGAGTGTTTGAT
-+
-;4@:7360AEC=B?77E9GFJ>??H1+,-'484.67258251(4.%0)-66448883434=6</1<<=?;@?;4=L3'47?@4<=?:9:&899@?AADBPE<A@C?E:2%:705(%;@BLJ@>;,%827?SKD=B?<<<HD=679;;;83?@-$$$,/<76982.*+$+0BE@;;;5.1$$$*%%%2574(':B<5#$$$'')***76:?@HD<6;=?@3=@E93<@@::$21675$//7/.,%$(&$&&&)(2&.0??=<0,,5<90='*/'/04--',('9.4;<>HBA,-$%,=80168@D:-5/.-'$##08=??HE@A>4.$)+/2/0255,,*&%*)3-#)99B40'?HHD0-0(/..<<:<1*(%%5,?<',+*
-@7e5675d5-2114-45cc-917e-631462362ae5
-CTGATGTGCTTCGTTCAGTTACGTATTGCTGCGCGCACTCTCTGTCGTCGAGCAGCGTCAGATGTATAAGAGTCAGGTATTATTTTTATAGTAATCAATTCTTCTGGGGGTTCTTTTCCGTTCTGTGTTTCACTAACCTTAATCATTAAAACATTCCCCTTTTCCTGAGAGCCGAGGGTTTGTCGCAATGGAGGGTGTTTGATAATATTGACTCAACAGTAGAGGATACGCTTGAAGTTCACTTTTATTGTATTTATCTATCGTTTGAGTATTTTTTGTGTTACTTCTGACCTTTCATCTCTTATTGTTATGGACATTTCTTTGGATATGTCCATGTTATAAAAATAGCTATCCCAAATGAGTTTCTTTATTTAAAGAGATGCTTTCATTTCTAAAGCTTTTTACTTTTAACAGAGCTGCTGGGTTTTTACGTCATAAAATGAAAAATATCGCGTCTAATATCGATGTTTTCCCAAAGTTATTTTCCGGATATTACATTAAGTGTTTTTAGTTGTTTGAGGGAGTTATGCTCAGAACACTTAAAATTTTTAAGTGGATATCTTTGTAATATTTAAACTTGCTCTCCATTTCTGTTTTTACGTTTACATAGTAATAATGTGTTTATTTGTACATCACTATGCCACTGTTTCTTTTTCTAGAAGTATAATCCAATAATATTACTTTTTGTAGTCCTGTTTGGTTGATTTTAACCAGTTTGTCGGAGTTTCTTCTTGTGATTATTGTGTTCTGGTCGCGTAATCTCTAAACTGAAAACAGAAAAACCACCTGAAATTGGTTTGATCGAAAAGTTAAGTCGGTTAGGGAACTGCTTAACCGGGTAACTGTCTTGTGCGAGACGAGGTCACCAAAACTGTCCTTTCAGTGTAGCTGTAGTCAGGCCATCACTTCAAGTACTCTCTTGAACCACTCTCGCACATCGACTTTTACCAATGGCTGCTGCCAGTGGCACTTTGTCGTGTCTTACCAGGTTGTTCAAGACGATAGTTACCGGATAAAGGCGCAGCGGTCAGCTGAACAGAGGGGGTTCATTTCCAGCTCCAGCTTGGAGCGAACGACCTACACCGAACCGAGATACCTACAGCGTGAGCTGAACCGCCGCACTTCCCGAAGGAGAAAAGGCGGACAGGTATCCGGTAAGCGGCGGGGTCGGAACAGGAGAGCGCACGAGGGAGCTTCCGGAAGCACCTGGTATCTTTATAGTCCTGTCGGGTTCGCCACCTGCAAGCGAGCGTCGATTTTTGTGATGCTCGTCAGGGGGCTGGAGCCTATGGAAACGCCTGCGGCACGCTGAAAGCTTCCTCGGTGCTTTGCTTTTTGCTCACGCATGTTCTTTCCGACTTTATCCCCGATTCTGTGGATAACCGTATTACCGCTTTTGAGTGAGCTGACACCGCTCGCCGCGGTCGAACGACCGAGCGTAGCGAGTCCGGTGAGCGAGGAAGCGGAAGAGCGCCTTATGTGACATTTCTCCTTACGCTCTGTTGTGCCGTTCAGCATCCTGTCCTGAGCGTTATCTCTCTGTCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGGTTCTTCTGCGGATTCGTGCAGCTTCTCACACATGGCGGCCTGTTCGTCAGCATCAGGTGCGTCAGTTTTCGAGCAGCGTCAGGCTCCGGACTTTTTTATGAATCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTTGTGGCAGTTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTTGACGGGCATTTCTGTCAGACAACACTGTCACTGCCAAAAAACTGCCGTGCGAGCTGTCCAGTAATTCAGACTTGCTGACAGGACAGGATGTGCAGTTGTTCTTGCCAGCACATACATGCGCTTCAACCCGCAGTGCCCTGGTCAGGGCTTTGCTTGCATTTTACCCATGTCAGATACGGAGCCATGTTTTATGACAAAGCGAAGTGGAAGTAGCCACGCGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACGGCAGAAGAAGACCAGGAAATCAGAAAAAGGGCTGCTGAATGCGGCAAGACCGTTTCCAGTTTTTACGAACAGCAGCTCTCGGTAGAGAGTTAACTTCGGCTGACCCAGTGATCGGGTACTGAAAAGAAGTTATGAGACTGGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGGGAGTATACGGAGGTGCCCCAGTCGCTATTACAGGTATCACCGATACCCTGTTATCCAGACTTATGGCAGATTATAGCTTCCCGGAGAAAACTGTCCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCCTGCATTCGCTTTCATGCATAGCTATACAGCAGAGCTGAAAACGATCCTGGCCCGCATCCTTCCTGTTTTCCCGGGGTAAAACATCTCTTTTTTACGGTGTCTGCGTCAGAATCGCGTTCAGCGCGTTTCAGCAGTGCGTACAATTACAGCATTATGTTAAATTTTTATAATTGTCTTTAAATTATTACCTTCATGATTTTGTGGAATTTCAGGTTGTTTCCTTATTTTTGATATAAATTCTTTTATCTCACTGAAGCAGTCATCGTCAGTATCAATGGTTTTGTTCTTCATTGATATGCCTATTCTGAAATCTGATTCCTTATTACAACTAAGGTAAACTTGAACTTTGCTTTCTTTTCATTATTTGCGTAAGCGTAATCAGGATGCAGGATGTAATAATAGATTCTTGTTCTTTTATTTTATTGAATAGATCGTCTATATATATCTAAACACCTCTTTCTTACGCGTGAGCAATGATTCAGATCTTCTATTGCGCCATTTCTTGTTTTCCTGGCATGATAAAGAAAGATATTTTTGTGCTTCCCGTTAATGGCTATTTCATTATGCGAGCTTGGTGATGAAATGTTAAGCTCATTTAATGTTGAAATTATCGATCTTTCCGTGTCGAAAACGATTCGTCGGCATCGATGATTAAGAATATACTTTCTTTTTCATTTAAAAGACTCTATGCTTTTAAATGCTCCCAAGGAGTTTGTTTTAGTTTGTGCTCCATTTTATTTTTCAACATAAACATCATTAATTCCTTCTATTTCAAGTAGATTGCAAAGGAAGTGAAAATCATCATCACCCTCAACAATGACTTTTTATAATCATTTATTTTCTCAGTTTCATTTATCTCACCTCCCAGCCATTTTCGTTGGGGGTGATGATGATTTCACTTCCTTTGCAATCTAGAAGAGAGTGTGATGTTTATGTTGAAAAAATAGATGGAAGACAAGGCTAAGGCAAACCTTCAGAAGGCGAAACTTTGTAAATCTTTTGTGTGTATGATACCGACAATTTTTGAGCACGGAAGATCTTTCAACGTTAAATGAAGCAACATTTAAATCATAAGCTCATATGTGAAATAGCCATTGGCAATAAAAATATCTTCCTTATCGTAGGAAAAAACAAGAATGTGGCACTCAGCAGAGATCAATCGTGCTCGCGATAATGAAAGAGGTGTTTAGATATATGTCTATTTGTCTCTTATACGCATCTCCGAGCCCACGAGACCGGAAGGTGCGCGCGGCGGTACGTGGC
-+
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
-@8d083c09-355f-4998-bc19-5a0d09c3650d
-GTTGTACTTCGTTCAGTTACGTATTGCTGCGCGCACTCTCTGGTCTCGTGACTCTGGAGATGTTATAAGAGACAGTTTTATAGTAATCAATTCTTCTGGGGGGTTCTTTTCCCGTTCTGTGTTTCACCTAACCTTAATCATTAAACATTCACTTTTCCCCTGAAGGCCGAGGTTTGCACATCGCAATGGTGTTGATAATATTGACTCTCAACATTGAGGGGACACGCTTGATTCACTTTGTGTGTTATCTATCGTTGAGTATTTTGTGTTACTTCTGACTTCTTTCATCTCTTATTTATTGTTGTGGACATTTTCTTTGGATTATGTGTCCATATTTATAAAATAGCTATCCCAAAATGGTTTTCTTTATTTAAAAGAGATGCTTCATTTCTGAAGCTTTTACTTATAACTGAAACTGCGGGTTTTTGCATCAAAATCAAATATCGTCAATATCGATGTTTTCCCAAAGTTGTTTTTCGGATATTACATTAAGGTGTTTTTTAGTTGAGCACAGGTTATAACCGACACTTAAAATTTTTGAGTGGATATCTTTGTCAATATTTTAAACTTGCTCTCCACATATTTATATTTACGTTTAACGTATCTGTGTGTTTATTTGTGTTAAATCACTATACCCACTGTTTCTTTTCTAGAGTATAATCAAAATAATATTGCTACCAGTCCTGAGCACGGTTGATTTTTAACCCAGTTTATCGGAGTTTATTCTTGTGATTATTGTGTTCTGGTCGCCAATCTCTAAACTGAAAACGAAAAACTACTAGAGAGGAGGTAGTTTGATCGAAGGTTAAGTCAGTTAGGGAACTGCAACAGGTAACTATCTTATGCAGAGACGAGTCCACCAAAACTGTCGCTTTCAGTGTAGCTGTAGTCCAGGCCATCACTTCCAGTACCTGTTGAACCTCGCACATCGACTTTTATAATGGCTGCTGCCAGTGTGCTGTCATTGTCTTACCGGTTGGACTCAGGGCGATAGTTACCGGATATAAGAACAGCGGTCGGGAGTGAACAGGGAGGTTCGTGCCTGGTGGCGCGGCTTGGAGCGAACGACCTGCCCACCTGAACCGAGATACTGGCGTGAGCTATGAAAGCGCCGCTACCGAGAAGGCGGACCGGAGTATCGGTAAGCGGCAGGTTGGAACAGGAGGCACGAGGGGGCTTCAGGGGGAAACGCCGCGACGTAACATAGTCCTGTCCGGGTTTCACCACCTCTGGCGGCGTCGATTTTTGTAGCGATGCTCGTCATGGGGGCGGAGCCATGGAAAAGCCGCCTGCGGCGCTGCTTCCCTCAGTGCTTTGCTTGCTCACATGTTCTTTCCATGACTTTATCCCAGTTCTGTGGATAACGCATTACACCGCTTTTTAGGTAGCTGACACCGCTCGCCGCGATCGAACGATGAGCGTGGCGGTCAGTGAGCGAGGAAGCGGAAGAAGCATATATGTGACATTTTCCATGCCGCGGCTGTTGTTGCCCGTTCATCCTGTCCTGAGCGTTATCTCTCATTATTGCACCACCTTTAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTGTTGCGCTTCTCACACACTGGCAGCCATTCGTCAACATCGGGTGCGTCCAGTTTTTCCGACAGCGTCGGGCTCTGACTTTTATGAATCCGCCACCATGTTAGCGAGTACGGCTTGCTGCCACTTCGTTCATCTTTTCGTTTTCTCAGTTCTGTCTGTCATCTACGTTTATTGTGATTATATCGCGTGCCACTTTTCGACTGTTTTACCGTTATTCTGCCGCTTGGCGGCTTTGACGGGCATTTCTGTCGGAACAACATGTCTTTATCCACGTCTCCAGAACCC
-+
-,',+0,//1+&7.-'943*-/+*-00&,.+&$#$#"'(92=;;79-/(.*&%&*$'*(/.-%$$%&$&%%'%%$%+1++'%*%&&&+*-//30*(&()-/+.:;9.025.&*((+*518<<:;6*)()&$$&'*+4748234/2,5)3(+%%(()*+--%&&'&*$*+('.879*#$#%%%)$%++'*'9+,/658**-$'(&&&-',-**+-226&46<BD=EAA88>@??;0733386:8?A@739;-:=@6@9((%5564/.$'):95+,),%&&%%%)*<<?>:C=8>/(*+.+-//;.%869F479;FB=D@<14:%,++-(-,,>.'';@<95248704,-+6))-+4454/&)/4;-)(10*,-&023*&,'+(./13.*231*'%(%&+,,,++$%%$$%$$'%%%##$#$&,8??D>:&)$)%,,*(%$#(+))3,.++&&$-))0/B347E@776?@>=@?7:;GC+6*.32.11*-,04$%'+-,35:86*$$%''$$$$$$&+%)('%&%&%137**.:=--/0()($$)933:.,''/5*#&&#$))-.,(01099938=7:&-&&$&%&(-$'%01+$..44)$%&'%$*,.*%'%(/31*...(*%$&&'*''0.7;9<@<@A>@>@AA;@?B<2-+')4BEBAA:<9;=C<>>77;7$'2'$%('224.*%&##$)-(+0/CAB@;22045;=>?7+%%*.)1A@.%(2&..%0336A8;;*-+-54*&'',%'(*,*)&5'12+)(*,55+/%%<?6)'&'$&&)&$'/,&%%$"'%0+))('&&&*;7:01109/81/&)101.'(&%#$&$(*-(&%486<0/+1/5//167964;((4%$0,,,)()(&9#%56>/+60+*,()*'+)+&&/'+)&''+*',55&($$$#+-*$)-,-01+>@@?<<=<4EDEJHD9)%)*/2355204*)+('0'$$"$$'&$$%.22/+)02')+2460(,)$+/*/++)&*793>@365))#''%%$&$'%%&*'$&*$%$''++%.5+%)3&1+&%%%%&$%##%$#'&*$$$%*$+20.047431+'%''%&&$,+54*,$/0'#%'%&(&'('*0220''))(&)(($$+#'+,'*)'(,2$%.+0$'#37*&6+-/**/6&.*%))$%/141614/(&,&$(*$,73+)'',+%)'''&)+$+&$&%$&$$$%%%&..0-**603$$/)-8:>0,#$&'0148'#$&$&.-/61/02=;6,%$&(59>+5A8.//#$&(%&+0$'$#%&$',-&*'&%./27698:05=458*&+278),2(.>,,,.777=@21).--9**9,+**,&2%%.-(4459/04)$&#(**)(130+$%&$$'')$$$""&+1111.)*7-((-,,,1-695<@6.0/)(7.(D**33.,13)46)&%'-,-+)$336/&%%%)=::<@@B8606&'-),03823;@<3..077&0%%#$$&)$'''313&&*444/582/*,,200,-//0.-87-?:8;5.,&#$%&%%$'$$%&')%,+./'0<7C89;9?CAJ99106+&'&*#-))$$%%%$''&,3.'$%$&#"#$'*+(,-.+$.'-1./5+'12-)+,##%&'=&.:99<5&&85=;=C>6%.+$*)$0++7(/55-9*2-1111/*+226004'('$&'(%%+,$#$%$/302'$$$&'().%)##%(#'#$.?;<BAHB;5=>?4/,1#)(/.**56./.;637+%./25-)).-10.-795,'+%%#&%(,##$$%*,)')*'*-9.$'(4=@8;=94&9::9;>35)6:2224:26'-20)+-20-)$$#&%''''&##%%++-+(&&+$)$**'',$&$$+0%
-@aee576d4-11da-4f8b-a076-1fd27eb129af
-GTTGTACTTCGTTCAGTTACGTATTGCTGCGCGCACTCTCTGGTCTCGTGGGCTCGGAGATGTGCTTATGAACGTTTACAAGTAATCAATTCTTCTGGGGGTTCTTTTCCGTTCTGTGACATTTCACTAACCTTAATCATTAAAACATTCCCGCGCCCTGAGAGCCAGGGTTTGCTGTCGCAATGGAGGGTGTTTGATAATATTGACTCAACATTGAGGACACGCTTGATTCACTTTGTGTATTGTATCTATCGTTGAGTATTTTTATTATTACTTCTGACCTTTCATCTCTTATTGTTATGGACATTTCCGTTGTGTCCATGTTATAAATAGCTATCCCAAAATGGGTTTTCTTTATTTAAAGAGATGCTTTGTTCTAAAGCTTTTACTTTTAACAGAGCTGCTGGGTTTTTACGTCATAAAATGAAAATATCGCGTCTAATATCGATGTTTCATTTTATATTATGCAAATGCTTTAAAAATAAAGCATCTTCAGATAATATTTTCATAACATGGACATGCTGAGATGAAGGTCGAAATAACCTGATAACAAAAGTGAATCAAGCGCAATCTTGCC
-+
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
-@b5a9dfcc-5c8a-4daa-ba44-8141646adf7d
-AAAGAATGTTTTACCCCGGAAAACAGGGAAGGATCACGCGATCAGGATCGTTTTCAGCTCGCTGCATAACTATGCATGAAAGCAGATGGTGATCTTTGGGGAACGGTGTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCGGGAAACTAATCTGCCATAAGTCTGGATAACGGGCGCGATGCTCCATGTGCTTGATCAGCACCTCCGCATACTCCACATACGACACGCTTGCCGTCGATAAAGAGTTTTTCTGTAACGCCTGATCTTCGCTTCCTTTCAGTACCGGTGATCATCAGTCAGTGATTCAACTCTTTTGAAGCACGCCAGTAAAAACCAAAAGCGATGCTTTCCACATTAAGCAAACACGCCGCTCTACGTTCTCTGGTCGCTAGCTGCCGCGTCGGATGAACGGAGGCGACTGATAGCCGCCTTGCCGCGCGTATTACTTCCACTTCGGTTTGTCATAAAACGCACTGGCTCCGTATTCGAAGAGGCATGGGTGTCAGGCAAGCCCTGACCGAATTAATTGCAGCAATGCATGCTATTGCGACATAGCAATTGCATCCTATCCTCATATCAACAGTTCGAATACTGACGAAACACGCGACGCAGTTTTGGCGTCTGACGTTGTTATCTGACAAATACCGCGTCAAAAGTAAGCGGCGAAATCGCGGCAGCAAAAGCATTCGAAAAGTGTTTACCGATACTGTCCCAACGCCGGTGATAATGGCTGGAATAAGACCGGAAGAAGCGAAAAGAATGAACAACCAGCAACAAACCAGCCATTACTCATATGTGGCGGGTTAAAGTCGAGCTGACTGCTCGAAAAACTGGACTTCCGATTCTGCTACGGCGAACAAACTATATGTGTAAAGCTGCACGACTCGCAAGAAGAACTCAGAGACAACATCAGGAACCCACACTTTGGTAAAAATAGCACAGAGGAGATAGCATCAGGATGGATTACCGAGCAACAACAGAATGGGAAAATCGCCAAGGCTCTTCTTCAGCTTCCTCTACTCTGTTTCTTACATCGATTCGAGACATTTCCACGTAAAGGCGGTCATCCTTCACTCAAAAGCAGTAATACGGTTATCCATGATCGGGGATAAGTCCAGGAGAACATGAGCAAAAACAAAGCACCGGAAGCAGCGCCACCGAACGTTTACTTATGACCCTTACGACGAGCATCACAAAATCGACGCTCAGCCAGGGTGTGGCCGACAGGACATAAAGATACCAGAGTGTTTCCCCTGAAGCTCCCTCGTAAAAAGCTCTCCTGTTCCGCGACCACCGCAACACCGGATTTTTATCCGCCTTTCTCCGCCGAGCGTGGCGCTTTCCTGCTCATGCTGATCTCGATTTCAGGTCAATGAGTCGTTCGCTCAAGCTGAACAATACCCCCGTTCAATACGACCGCTGCACGCCTTATCCGGTAACTATCGTCTTGGGTCAACCAGGTAAGACGCGACAAAGCCACTGTGGCAGCCATTGGTAAAAGTCGATGTGCGAGAGGTTCAAGAGAGTCACTTGAAGTGATGGCTGACTACAGCTACATGAAGGACAGTTTTGGTAATCAGTCTCACTGGTTTGATACTAAGTTGTCAGTTATTTGATACTGTGTTGCTAAGATAAACTCTTTCTATTTTGGAGTGTTTTCATTACTCCCAGTTGTAGCGGAAGTAAGGCCATTACAATGATACAAGAAGAAGCTAAGCGTTTACTGACTGGTTAGAATCGATCAAACAGGACTATAAGTATTCAGCATCATTTTGGATATACCATTCAGAAAAAAGCTGATAGCAGTGGTATAAAGCACAAACACACTATTACTATGTAAACGTAAACAGAAATGGAGAGCAAGTTTAAACATGATAGATATCCACTTAAAAAATTTTAAGTGTTTTCGGAAACATAACTCTCAAACAACTAAAAACACTTAATGTAATATCCGGAAAAACAACTTTGGGAAAACATCGATATTGAACGCATTTTTTTCATTTATGACGTAAAAAAACAGCAGCTCTGTTAAAAAGTAAAAAGCTTTAGAAATGCACGACATCTCTTTTAAATAAGAAAACTTCCATTTGGGATAGCTATTTTTATAACATGGTTTATCAAAGAAATGTCCATAACGACAAGAATGAAGGTCGAGTAACCTACTTAACTCAACGATAGATAACACACAAGGTGAATCAAGCGTGTCCCTCAATGTTGAGTCCAGTATTATCAAACACCCCTCCATTGCGACAAACCCTCGGCTCAGGAAA
-+
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
-@15186119-b3bc-4b5c-9166-9fa0a7e06d54
-CATTTGTCACCCCCGTTCAGATTTGTGTGCTGCGCGCGCACTCTCTGGTCTCGTGGGCTCGGAGATGTGTAGAGCAGATCAAAGATATGATCAGCTGGTGAAGCAGCGAAAACCAATAATCAAATATTTACAGCAACACACAGCCATAATGAATAATATGTGTGCGATAAACGAATTAGATGAAAAAAGAAAAGATATATCTTACATAAGACTGGAAGAGACTTCAAAGATCTCAAAAACCCGGCAGTACAATTTAACATAAGATGAATTTTCTTTTCCAATTGAAAATATTTAGGAGTGAGATAAATGAAACCGAGAAAAATAAATGATTATAAAAAAGTCATTTTCGTTGAGGGTGATGATGATTTTCCGCTGTTGCAATCTACTTGAAATGAAGAATTAATGATAACATGTTGAAAAATAAATGGAAAGACAAAACTAAAACCAAAACCCTTAGAACGTTTTTAAAAAGCATAGAATGCTGGCTGAAAAAGAAAGCCTATTCTTGTCATCGATACAAAACTGTGAATCGTTTCTACAGCCCGGAAAGATCGATAATTCAGCATTAAATGAAGCTTAACATTTCATCACCAAAGCTCTACTTTTATAATAAATAGCCATTAACGGAGGCACAAAATATCTTTCTTTATCATGCCGGAAAAACAAGAATGGCGCAATAGAAGAATCTAATCATTTCGCTCACGCGTGAAAGGGTGTTTTTAGATATATGGGTGATCATTCAATAAAGAATGAAAGAACAAAGATCTATTACATATAGATCCTGATTGCGCTTGCCCAAATAATGAAAAGAAAGCAAAAGTTGAAGTTTACATAGTTGCTTCAATAAGAATCAGATTCTAGAATGAGCACTTATCAATGAAGAACAAACCATTTGGTACTGACGATGACTGCTTCGATGAGATAAAAGAATTTATAACTCAATATGAAACAACTCCACTACCAAAATCATGACCATAATGACTAAAGACAATTGCAAAATTTAACATAATGCTGTAATTGTACGCACCTTACGGGACCCGCGCTGAACGCGATTCTATTGACGCAGACACCGCAAAAGAGATGTTTTACCCGGAAAACAGGAAGGATGGAAATCAGGATCGTTTTCAGCTCGCTGCATAGCTATGCATGAAGCGAATAGTTTATCACTTTGGGAGCTTACGGTGTTTCATACACCGTCACCTGTTAAACAGTTTTCTCTCCGGGAAGCTAATCTGCCATAGAATCTGGATAACAGGGCACGGTGACCACTCCGTAATAGCGATCAGCACCTCCGCATACTCCCTGTCCCCGACACGCTTTGCCGTCGATAAAGTTTTTCTGTAACGCCCCAGTCTCATAACTTCTTTCAGTACCCGATCATCAGTCAGTGAGTTAACGCTTACCGAGAGCTGCCGCCGGTAAAACCCAGGGCGGTCTTTGCCGCATTCAGCAGCCCTTTTTCGATTTCCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATAGCCCGCCTGCGCGTATTACTTCGCTGATTTTGTCATGAAACATGGCTCCGTATCTGACATGGGTGTCGGGGCAAAGTGATCGGGGCAATTATAATAGCGTGCATGTATACGCGGTATAACAGTACACATCCTGTCTGTCAGCAAAGCTCGAATTACCGACAAAGGCACGGCAGTTTTTTGGCAGTGACAGTGTTGTCTGACCAGAAATGCCCGTCAAAAGCCAAGCGGCAGAATAACGGCAGCAAAAACAGTCAGAAAAGTGGTACGCGATACTCAATCTGCCCAACGCAGATGACCAGACAGAGACGGAGAAAACGAAAAGATGAACAAGCAGCATGAAGCCATTACTCAACATGGCGGGATTCATAAAAAGTCAGAGCTGACGCTGCTCGAAAAACTGGACGCACCCGATGCTGACGAACAGGCTGCCATGTGTGGCTTCCGCGAAACTCATGAAGAACTCAGAACAGCATCCAGACACGCTTTGAAGTGATAGAAAATGGCACAGGGTGCGCTCAGGACAGGATGCCGGGCAGCTACAACAAGAGCGTAAGGAGAAAATGTCACATGAGCACTCTTCCCGCTTCCTCGCTCACTGACTCGCGCTACGCTCGGTCGTTCGACTGCGGCGAGCGATAATCAGCTCAAAAACTAATAAGGTTATCCACAGAATCAGGGGATAAAGTCGGAAAACATGTGAGCAGCAAAGCACCAGCGCGGAGAAGCCAGCGCCGCAGGCGTTTTCGCAGGCTCCGCCCACGGCGAGCATCACAAAATCGACGCTCAAGCCAGAGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGTGTTTCCCCTGAGCTCCACTCGTGCGCTCTCCTGTTCCGACCCTTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCTTCGGGAAGCACTGGCGCTTTCTCATAGCTCACGCTGTGCAAAAATTACTCTCGGTTCCGGTGGAGTCGTTCGCTCCGGCTGGGCTGTGTGCACAGGCTGCGTTCAGCCCGACCGCTGCGCCTTATCCGGTAACTATCATTCGGGTCCAGCCCGGTAAGATTTGACAAAGCGCCACTGGCAGCAGCCATTGGTAAAGTCGATGTGCGAGAGGTTCAAAGTACTTGAAGTGATGGCCTGACTGGCTACACTGAAAGGACAGTTTTGGTGACTCGTCTCGCACAAGACAGTTACCTGGTTAAGCAGTTCCCCAACTGACTTAACCTTTCGATCAAACCACCTCCCAGGTGGTTTCGTTCAGTTAGGAGATTACGACCAGAACACAATCACAAGAAGAAACTCCGACAAACTGGTTAAAATCAATCCAAACAGGACTATAAAGTAATATTATTTTGAAGTTATACTTCTAGAAAGGAAACATTGGCATAGTGATGCATAAATAAACACATTATTACTATGTAAACGTAAACAGAAATGCGACAGAGTTTAAACATGATAAAGATATCCGCCCAAAAATTTTAAGTATTTTTCGAGAGCATAACTCTCCGACGGCGCTAAGGAAAACACTTAATGCAATATCCGGAAAAAACAACTTTGGGAAAACATCGATATTGAACGCGATATTTTTCATTTTATAATAAAAACCCGTAGCTCTGTTAAAAGTAAAACTTTGAAATGAAGCATCTCGCAAATGAAAACTCATTTGGGGATAGCTATTTTTTTTCTCTTTTATGGACATCAATCCATAACAATAAGGGATGAAGATTAGTGACTTTAAAAATACTCTCAACGATAGATAACACACAAAGTGAATCAAGCGTGTCCCTCAATGTTGAGTCAATATTATCAAAGCACCCCTCGGCGACAAACCTCAAGCAAATAAGAGGTGGCATTAATGTCAAACTCAACATTGAGGAACACGTATTGATATCTGTCGTTGAGTGTTTGTCACTTCATTTAAATATTGGTAATCCTGTTACAACATATCATTTAAATGAGTTTCGAGAGATATTTCTCTAAAGCACTTTTAACAACGAGAAGCTGAGTTTAAAATAAGCATACTGAAGTTGTTTTTAATACATAAAAGCAGTGGATTGTTTGGTCTTTCTCAGCTTAAGGCCCGCAGAGATGTCTACATCATGTTTGACATCTCCATTTCTGTTCATTACATATTTGTGTTTATTTATCTGTCACTTGCTGTTTCTTTCTGAAATCATATCCAGCAATTTCATTTACATTGATTGTTGTCGGGTTTCTTCTTATTGTTCTGAATAAAACTGAAAACGAAGCGCAAAGAACTTTAACGGAAGCCAGCTTTACTTATACACATCTGACACTGCCGACATAGCGGCAGAGTGCACTTTGCTTTTAGCAATGCATGT
-+
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
-@29d947af-d859-460c-917e-f66f103f3f1b
-AATTGTACTTCAGTTTCAGTTACGTATTGCTGCGCGCGCACTCTCTGGTTCATGGGCTCCGGAGATGTGTATAAGAGACAGTGATAATAGTCGACAACATTGAGACACGCTCCCAGTTCACTGTGGTATCTATCGTTGAGTATTTTTGTGTTACTTCTGACCTTTCATCTCTTATTGTTATGGACATTTCTTTGGATGTGTCCATGTTATAAAATAGCTATCCAAAATGAGTTTTCTTTATTTAAAGAGATGCTTCATTTCTAAGCTTTTTACTTTTAACAGAGCTGCTGGGTTTTTACGTCATAAAATAAATATCGTCTAATATCGATGTTCCCAAAGTTCAATTTTCGGATATTACATTAAGTGTTTTTAGTTGTTTAGAGTTATGCTCTCGAAACACTTAAATTTTAAGTGGATATCTTTTATCATGTTTTAAACTTGCTCTCCATTTCTGTTTACGTTTACATAGTAATAATGTGTTTATTTATGCATCCCTTTATTACTGTTTCTTTTCTGAAGTATAATCAAAATAATATTACTTTATAATTCTGTTTGGATTGATTTTAACCAGTTTGTCGGAGTTTCTTGGCGTGATTATTGTGTTCTGGTCGTAATCTCTAAACTGAAAACGAAAAAAACCACCTGGGAGGTGGTTTGATCGAAGGATTAAATCCAGTTGGGGAACTGCTTCCAACCAGGTAACTGTCTTGTGCAGGACAGATTCACCAAAACTGTCCTTTCAGTGTGCTGTAGTCAGGCCATCACTTCAAGTACTCTCTTGAACCTCTCGCACATCGACTTTTACCAATGGCTGCCAGTGGCGCGCATCGTGTCTTACCGGGTTGGACTCAGACGATGGTTTTAGGATAAGAGCGCAGCGGTCGGGCTGAACAGAGGGTTCGTGCACACAGCAGCTTGGAGCGAACGACCTACACCGAACCAGGAATACCTACAGCGTGAGCTATGAAAGCGCCGCTTCCCGAAGGAAGGCGGACAGGTATCCGGTGGCGGCGGGTTAGACGGAGAGCGCACGAGGCTTTGGGGAAACACACGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTCTGGCTTGAGCGTCGATTTTTGTGATGCTCGTCAGGCGGAGCCTATGGAAAAACGCCTGCGGCGCTGGCCCTCCGGTGCTTTGCTTTTGCTCACATCGTTCTTTCAAACGCATCTGATTCTGTACGGTTAACCGTACTACCGCTTTTGAGTGAGCTGGCGCGCTCGCGCATAGTCGAACGATGAGCGTGGCAGATCGGTGGCGCGAAAGAAGCCGGAAGGCGCCTATCTTGACATTTTCATCCGCCATCTGTTGTTGCTGGTCGGCGTCTGTCGAGCGATTATCTCTCAATATGCCTTCCGAAGGCGTGTCGGATGCTGAATACCGGAGTTCTTCTGCAGTTCGTGCGGCTTCTCACACATGGCAGCCTGTTCGTCAGCATCAGGTGCGTCAGTTTTCGAGCAGCGTCGGAAATCGACTTTTTATGAATCCGCCATATTGGTGCGGCTTGCTGCTGCTTGTTCATCGCACTTTGTTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGGGTTATCACGTACCACTTTTCAATGTTTGCCATGATTATTACACGCTTGGCTTTCGGCCGGGGCCCATTTTCTGTCGAACATACATCTTCACCAAAAACTGCCGTGCCTTTGTCGGTAATTCGAACACTGAAGCGGGACAGGATATTACTATGAGTTGTTATCTGCGCATGCGTACGCCTATTACCAGTTGCCCTCAGGTCGAACTTTGCCAAACCGCCATCAGATGGAACTGTCTTTGGCGGCAGGCGGCTCGTATCGTGTCGATCAGAGTAAAGCTGAACAGAGGTGATCATAAATCAGTCGTATAAAGATGCTTCATTGCATCTGTCTGTGGTGAAATCAGTAAACCTAATGATGGTCCACAATAGTGATAGTGTTCTGACAAAT
-+
-$$$%$$#%%%%%((9-0*510&)12/05=AC?:@3;00+(86&&.,$%$'&%+04:79$A183>7=0')358./0')'.),5*+-'(%&$%#%$)&&*)***&3*)/0)*+$+%%'*+*##)#&$$($05:78><A58/:324:@FA,10664023@7HGA@>??A@89'>?:3:>27-$('(*(9<>G?NMF?AGGCE:;=>@>;;303464/)*&/8:%%=FGFHAECIA@SH<B>KFJGCGQ7'.33957<>5$$&+'*()0/0-***57=@CA<<3@//A<;9--21@KGRH;7<69C8<CE:2+%*2,,602382'(098844?@::>@C<>6&2,/%*+4D1>375@@DC>DFJA/*$0*49D:/*):?>==5)((4559<>CH>6:-,.034--010/BEF9241<;=@8?<@AAGD;6,&$$0200?ADAGH6GC>83/>AD>..-<>);;:EEH@?@-%99BEC>@@FGD00/089>=9883**.''*'$$$59<:??<9@<F>7-$$+5>?A@>8<=>;F?BEDFBBB;<AA<9,-*/''''7922:HFEDDJNE>A=B@?@AJ1,<'+%2064.1,$'($,--A@8:;,/0;==907=?8789:;)7&<>2)5661A;922=;997/44-..3+-.&//B=?JG=;525/-,(5$5788:$$9/<7/&''%$(26+'''%&-.58378>?=8@?;<9<670)$%'&&%%&*(2+*<89<;?>+$47/1.3*,*$#%$)((&&0.++(<=?9C:8B3F247DF59=8FAC=<C@?B,=B56=@BB>DDDUOJB87<DB?82**'%'$*6),,)$'((058E79:8:8DJA?IIA56715.$,))$#,#&)'&&+/9--&'$$+6>408@83+C*-)+-0/81,9%45BD:/)'+,+,--,%%')&&&(*)(9117<@?ECEA=:DA99A>6,/**1&',,,,63DB>==:3/81./.).*+**(%$%)),'($#(*$',,259>-+)+).%%-$(.#%,&+4#&.'*''*5%,33*53,*&**%&*))*&%(''46,('&%%#$&6:;>=94::9::?G4-;$&<CEEA;=5/9;==@89661.+9<B<EGCCDDCE<64/<>AF?74713-5(+'&01478*,)&%'/69<<<9:6821//&&#(024=29C=9<=@>;?@BC=?@@35('&%"%$$$%,$%$(&)$$$'777;=.,,2@25*.;=<5/;8<<7??7248740/2666<20-($#)&()-+.,&%%$$08&&,)(&%'$&%%*(+*%(%'(%)(%&#&'&&%$%'&)%+'+%%'',%#$%((&%(.(/%)*()##&&/'10$&,$%%&)$%)$&#$'%',60,4*$$%'(&+%$1)(,6'%&)#$##%#%%$*$'#%%$)(&&%'%-1+0*&%'&&$#%)#%%)07(.+*&(*&*682/;24)0)):>6@:+8@7;23+-#89=;;3.,5/3,051.%.,'&''&'$%.34-(%%')&,20++#'%&)*)-*8;;?>2))('0))/589+%%),#%'$(%+;;;9<E5.012:;6:8.$&%$#$#')'#01106+-%--3:?888@77:7>=BF3A:EA'6(+%&%$&&)'$($&#%%&&,,,-/$&('/2+%%'#(&&&($#*%%#/16;:8=444/(&('&#&&&%$$''(')%'%,)$$%%#$#$%&+&'###$)++(&()',,))%*,*,++%9$&-#%%)%%%$%%#$%((%1$*/'$#)')&$%'$$&##%$%'.'''%&('#%%$##$(%&&.''&)'()&#$$$*,%%%%,%$+**-#$$"#$#$$$$&$$'%&%+&&$')%#&#$#&$%#12.&(&#%%$('&'*,*'$$)*'#%#%$'%''$%$&%'('$$$&$%&$'$(+%&&&,##"$%#$'&'&&$&%%'%$$$##%&'%%($'%%+&#%+$%%#%%$(('$%&$&#&*'($##%%$%#%'$'$$&%"%&'%#$$#%$$$(*0,0$%%#
-@edfdd3cd-6f02-40df-a659-16f32c6af9ed
-CGGTAATACTTCGTTTGATTACGTATTGCTGCGCGCACTCTGCGTAATCGGCAGCGTCAGATGTATAAGAGACAGCAGATAATGTGGCTCAACATTGGGGACACGCTTGATTCACTTTGTGTGTTATCATTGAGTATTTTACAATCATGACCTTTCATCTCTTATTGTTATGGACATTTCTTTGGATGTGTCCATGTTATAAAATATTTATCCCAAAATGAGTTTTCTTTGTTTAAAGATGCTTCATTTCTAAAGCTTTACTTTTAACAGAGCTGCTGAGTTTTTACGTCATAAGAATGAAAATGTAACGTCTAATATCGATGTTTTCCCAAAGTTCTATTTTTTCGGATATTGACTGTTAAGTGTTTTGGATTGTTGTTTGAGGATATAACTCTCAAACACTTAAAATTTTTAAGTGGATATCTTTTATCATGTTTAAACTTGCTCTCCATTTTCTGTTTACGTTTACACCTTAGTAATAATGTGTTTATTTATGCATCACTATCACACTGTTTCTTTTCTAGAGTAATCAAAATAATATTACTTTATAGTCCTGTTTGGATTGATTTTAACCAGATTTGTCGGAGTTTCTTCTTGTGATTATTGTGTTCTGGTCGTAATCTCCCAAGCTGTGCTAAATAGAAACGAAAAAAACCACCTGGGAGGTGGTTTGATCGAAGATTAAGTCAGTTGGGGAACTGCTTAGCAGGTAACTGTCTTGTGCGAGACGAGTCACCAAAACTGTCCGCTTTCAGTGTAGCTGTAGTCAGGCCATCACTTTGAAGTACTCTCTTGAACCTCTCACGCACATCGACTTTTACCAATGGCTGCTGCCAGTGGCGCTTTCGCCGATGTCTTACCGGGTTGGACTCAAGACTGATAGTTACCGGATAAGGCGCGGCGGTCGGAGCTGGGGTTCGTGCACACAGCCCAGCTTGGAGCGAACGACCACCGAACAGTCTACCCTGGCGTGGCGGGCTATGAAAGCGCCACGCTTCCCGAAGGGAGAAAGGCGGACAGGTATCCGGTAAGCGGCAGGGTCGGAACGGAGAGCGCACGAGGGGGCTTCCAGGAAACACCTGGTATCTTCATGGTCTATCGGGTTTCGCCACCTCTGGCGAGCGTCGATTTTGTGATGCTCGTCCGGGAGCCGGAGCCTATGGAAAAACGCCTGCGGCGCTGGCTTCCTCCGGTGCTTTGCTTTTTTGCTCCGCATGTTCTTTCCGGCACATCCCCCGATTCTGTGGATAACCGTATTACCGCTTTTGAGTGAGCTGACACCGCTCGCCGCAGTCGAACGACCGACATCAGCGAATAATTGAGCAAAGGAAGCAAGCCTGCTATGTGACATTTTCTCCTTACGCTCTGTTGTGCGTTCCGGCATCCGCTCCTGAGCGTTATCTCTCTGTGCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGGTTCTTCTGCGAGAGTAATTGCGGCTTCTCACATGGCAGCCTGTTCACATCAGCATCGGGTGCGTCCAGTTTTTCCGAGCAATCAGGCTCTGACTTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCCCGTTTATTGTGATATATCGCGTACCACTTTTCGACTGTTTTGCTGCTATTCTGCCGCTTGGCTTTTTGACAGGCTGTCGAACAACACTGTCACTGCAAAAAACTGCCGTGCCTTTGTCCCGGTATTCGAGCTTGCTGACAGGACAGGATGTGCAATTATTATACCGCGCATACATGCGCTATTACAATTGCCCCTGGTCGAGGCTTTTGCCCCGACACCCATGTCGAATGCGAACCATGTTTATGGCGACGAAATTGAAATGTCGCGCAGGCAGGCTATCAATCCGCCCTGTTCGTCTGACAGCGAAGAAGACCAGGAAATCAGAAAAAGGGCTGCTGAACGGCAGACCATTCTCCAGTTTTTACGGGCGAAGCGAAAGCTCTCGGTGAAAGTTAACTCACTGACTGATGATCGGGTACTGAAGGAAGTTATGGGAACAGGGAGCGTTACAGAAAAGCTGCTTTATCGACGGCAAGCGTGTCAGGGACAGGAGTATCACGGAGGTGCTGATCGCTGTACGGGTATCACCGTGCCCTGTTATCAGACTTATGGCAGATTAAGCTTCCGGAGAAAACTGTCGAAAACGGACGGTATGAACACCGTAAGCTCCCAAAGTGATGCCATTCGCGCTTTCATGCATGGCTAATGCAGCGAGCTGAAAACGATCCCGGCGCATCCTTCCTGTTTTCCGGGGTAAAAACATCTCTTTTTGCCAGTGTCTGCGTCAGAATCGCGTTCAGCGCGTTTCAGCGGTGCGTACAATTACAACATTATGTTAAATTTTATAATTGTCTTTGATCATTGCACTTTATGATTTTGTAGTTTAGGTTGTTTCCATGACCACGATATAAATTCTTTTATCTCACTGAAGCAGTCATCGTCAGTATCAATGGTTTTGTTCTTCATTGATATGCCTATTCTGAAATCTGATTCCTTATTACAATAAGGTAAACTTGAACTTTTGCTTTCTTTTCATTATTTGGGTAAGCGTAATCAGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTGTACACCCATTGAATAGATCATATATCTAAACACCTCTTTCTTACGCAATGAAACAATATCGGATAAATCTTCTATTGCGCCATTCTTGTTTTCTGGCATGATAAAGAAAGATATTTTTGTAGCTTCCGTTAATGGCTATTTCATTATGCGAGCTTGGTGATGAAATGTTAAGCTCATTTTAATGTTGAAATTATCGATCTTTCCGTGTCAGAAAACGATTCGTCGGCATCGATGATTAAGAATACTTTCTTTCATTAAAAAGACTCTATGCTTTTAAATGTAAGGGTTTGTTTTAGTTTTGTCTTTCCATTTATTTTCAACATAAACATCATTAATTCCTTCTGTTCAAAGTAGATTGCAAAGGAAGTGAAAATCATCCATCACCCTCAACGAAAATGACTTTTTTTATGTCATTTTATTTTTCTCGGTTTCATTTATCTCACCTCCCAGCCATTTTCAACTTTCAGAAAAGAAAAATCATCCATGTTAAATTGCATTTGTAGGTTTTTGAGATTCACTTGTCTCTTCCCAGTCTTATGTAAGATATATCACTTTCTTTTTCTGTCTAATTCATCGCACATATTACATCATGGCTGTGTGTTGTTGCAATATTTGATTATTATTATTGGTTTTACTGCTTCTATCAAAGCGTTGATCTGTATCTTTGATTACTGGAGTAATGAATTCCATTTTCTATCTCATCAGTAGAATAATTGAGTCTTTTTGAACTAAAGATTGAGCTAATGAAAGACAGCGCTCTACTTGCCTCCTTCACCAAGCATTGATATTTCATTTAATTCATAGTCACATATCTAAAAAAATCTCTTTGTTTTGATCTGTTGCTATTATTGCAATATCGTTAACCAATTCTATTATCTATTCACTAGGTTGCCTATTATTTCATCTTTTCTTTTTGTGTTAATAGTTTGATACGTTTTTTTATCGTTTAGCACCTTTGTTTATGTTTCTTGATGGTTATTATCGCGCGGTTTTGAATTCATATAGCTTACCTTTTTTAGTTTGTTTATTTCTCCGTTTATTTCTTGTGCTTTTGTGTTATTTTTATGGTAATCAATTCTGGGGGTTCTTTTTCCGTTCTGTGTTTCTTTAACCTTAATCGATAAAACATTCCCTTTTCCTGAGAGCCGAGGGGTTTGTCACCAATGGAGGGTGTTTGATAATATATTACTGTCTCTTATACGCATCTGACGCTGCCGACGACAGAGAGTGCGCGCATGACGCGTAAC
-+
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
-@6d0657b5-b18a-4d1f-8c20-a60213d0ea58
-GTTGTACTTCGTTCAGTTACGTATTGCTGCTAATCTGCCATAAGTCTGGATAACAGGGCACGGTGATACTCCGCTAATAGCGATCACTTTATCACGCCTCCTGTCCCAAAAACCACGCTTGCCGTCGATAAAGAGTTTTTCTGTAACGCCCCAGTCTCATAACTTCTTTCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTACCGAGAGCTGCCGCCGTAAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCTTTTCTGATTCCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATAGCCCGCACCGCGTATTACTTCCGCTTCGTTTTGTCATAAACGCGCTCCGTATCTGACATGGGTGTCGGGGCAAAGCCCTGACCAGGGCAATTGTAACAGCGTGCATGTATGCGCGGTATAACAGTGCACATCCTGTCCTGTCCAGCAAGCTCGAATTACCGACAAAGGCAAATTTTTGGCAGTGACAGTGTTGTCTGACAGAAATGCCCGTCAAAAGCCAAGCGGCAGAATAACGGCAACAAAACAGATCGAAAAGTGGTACGCGATATAATCACACAACGCAGATGACAGACAGAACGGAAGGAAAACGAAAAGATGAACAAACGGCAACAAGCCGTACTCAACATGGCGGGATTCATAAAGTCAGAGCCTGACGCTGCTCGAAAAAACTGGACGCACCCGATGCTGACGAACAGACTGCCATGTGTGAAGCTGCACGAACTCGCAGAAGAACTCCAGAACAGCATCCAGACACGCTTTGGAGAGTAGAAAATAGCACAGAGAGATGGCAGCTCAGGACAGGATGCCGAACGGCACAGCAGAGCGTAAGGAGAAAATGTCACGCAAGGCGCTCTTCCGCTTCCTCGCTCACTGACTCGCTACGCTCGGTCGTTCGGCTGCGGCGAGCGGTGTCAGCTCACTCAAAAGCGGTAATACGGTTATCCACAGAATCGGGGGATAAAGTCGAGAGAAACATGTGACAAAAAGCAAAGCACCGGAGAGGAAGCCAGCGCCGCGAGAGCGTTTTCTCGAAACCCGCCCCCCCTGACGAGCATCACAAAAATCGTCAAGCCAGAGGTGGCGAAACCCGACGGGACTATAAGATACCAGGTGTTTCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCGGTTCGGTGTAGGTCGTTCGCTCCAAGCAGGCTGTGTGCACGAACCCCCGTTCAGCCCGACCGCTGCGCCTTATCGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACAAAGCGCCACTGGCAGCAGCCATTGGTAAAAGTCGATGTGCGAGAGGTTCAAGGAAGTACTTGAAGTGATGGCCTGACTACAGCTACACTGAAGGACAGTTGACGACTCGTCTCGCACAAGACAGTTACCTGGTTAAGCAGTTCCCAGCTGACTTAACCTTCGATCAAACCACCTCCCCAGGTGGTTTTCGTTTTCAGTTCAGGAGATTACGACCAGAACACAATAATCACAGAAGAAACTCCGACAAACTGGTTAAAATCAATCCAAACAGGACTATAAAGTAATATTATTTTGATTATACTTCTAGAAAAGAAACAGTGGCATAGTGATGCATAAATAAACACATTATTACTATGTAAACGTAAAAACAGAAATGGAGAGCAAGTTTAAACATGATAAAGATATCCATAAAAAATTTTAAGTGTTCGAAACATAACTCTCAAACAACTAAAAACACTTAATGTAATATCCGGAAAAAACAACTTTGGGAAAACATCGATATTAGACGCGATATTTTCATTTGCTGACCGTAAAAAACCAGCTCTGTTAAAAGTAAAAAGCTTTAGAAATGAAGCATCTCTTTTAAATAAAGAAAACTCATTTTGGGATAGCTATTTTTATAACACTGGACACATCCAAAGAAATGTCCATAACAATAAGAGATGAGTCAAATAACTTACAAAAATACTCAACGATAGATAACACACAAAGTGAATCAAGCGTGTCCCTCAATGTTGAGTCAATATTATCCTGTCTCTTATACACATCTCCGAGCCCACGAGACCAGAGAGTGCGCGCGCAGCAGTACGTAAC
-+
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
-@a7244964-7a0d-47e2-9687-6846f723c232
-GTTGTACTTCGTTCAGTTACGTTGCTGCGCGCACTCTCTGGTCTCGTGGAAGCCAGAGATGTGTATAAAGACAGACGATTGAGTTGCACGCTTGATTCACTTTGTGTGTTATCTATCGTTGAGTATTTTTTGTGTTATCTGACCTTTCATCTCTTTATTGTTATGGACATTTCTTTGGATGTGTCCATGTTATAAAAATAGCTATCCCAAAATGAGTTTTCTTTATTTAAAGAGATGCTTCATTTCTAAAGCTTTTACTTTTAACAGAGCTGCTGGGTTTTTACGTCATAAAATGAAATATCATCGTCCTAATATCGATGTTTTCCCAAAGGTTGTTTTTCGGATATTACATTGTTAAGTGTTTTTAGTTGTTTGAGAGTTGTACTCTCGAAACACTTAAAATTTTTAAGTGGATATCTTATCATGTTTAAACTTGCTCTCCATTTCTGTTTACGTTTACATAGTAATAATGTGTTTATTTATGCATCACTATGCCACTGTTTCTTTTCTAGAAGTATAATCAAAATATTATTACTTTATAGTCCTGTTTGGATTGATTTTAACCAGTTTGTCGGAGTTTCTTCTTGTGATTATTGTGTTCTGGTCAATAATCTCCTAAACTGAAAGCAGAAAAACCACCTGGGGAGGTGGTTTGATCGAAGGTTAAGTCAGTTGGGAACTTCAACCAGGTAACTGTCTTGTGCGGACGAGTCACGCAAAACTGTCCTTTCAGTGGTGTAGCAGTAGTCAGGCCATCACTTCAATTACTCTCTTGAACCTCTCGCATCGACTTTACCAATATGGCTGCTGCCAGTGGCGCTTTGTCGTGTCTTACCGGGTTGGACTCAAGACGATAGTTACCGGATAAAGGCGCAGCGGTCGGGCTGAACGGGGGTTCGTGCACACAACCAGCTTGGAGCGAACGACCTACACCGAACCGAATACCTACAGCGCTGACTATGAAAGCGCCACGCTTCGAAGGAAAGGCGGACAGGTATCCGGTAAGCGGCAGGGTCGGAACGGGGAGAGCGCACGGGGAGCTTCCGGAAACACCTGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTCTGGCTTGAGCGTCGATTTTTTGTGATGCTCGTCGGGGCGGAGCCTATGGAAAAACGCCTGCGGCACTGGCTTCCTCCGGTGCTTTGCTTTTTGCTCACATGTTCTTTCCGACTTTATCCCCCGATTCTGTGGATAACCGTATTACCGCTTTTGAGTGAGCTGACACCGCTCGCCGCAGTCCAGCGACCGAGCGTAGCGAGTCAGTGAAACGAGCGGAAGAGCTTACTGCTATGTGACATTTTCTCCTTACGCTCTGTTATTGCCGTTCGGCATCTGTCCTGAGCGTTATCTCTCTGTACTGTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGGTTCTTCTGCGAGTTCGTGCAGCTTCTCACACATGGCAGCCTGTTCGTCAGCATCAGGTGCGTCCAGTTCGAGCAGCGTCAGGCTCTGACTTTTTATAGATCCGCCATATTTGGATTTGGCTTGCTGCTGCTTGTTCATCTTTTCGTTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTGACGAATTTCGTGAACTGTCACTGTAAAAAACTGCCGATGCCTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTGGTGTTATACCGCGCATACATGCACGTAATACGTTGCCCTGGTCAGGGCTTTGCCCCGACACCCATGTCAGATGCGGAGCCATGTTTTATGACAAAACGAAGTGGAAGTAATACGCGCAGGCGAGGCTATCAGTCGCCCTGTTCGTCCTGACTGACAGAGAAGAAGACCAGGAAATCAGAAAGGGCTGCTGAATGAGCAATACGTAAC
-+
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
-@83afce0e-57fa-4c9e-885c-aaae39bc44bb
-GTTGTACTTCGTTCAGTTACGTATTGCTTTTGGGAGCTTACGGTGTTCAGCACCGTCTGTTTTCGACAGTTTTCTCTCAGGAAGCTAATCACCATAAGATCCTGGATAACAGGGCACGGTGATGCCGTATGTGATCAGCACCTCCGCATACTCCTGTCCCCGACACGCTTGCCGTCGATAAAAGAGTTTTTCTGTAACGCCCCCAGTCTGTAACTTCTTTCAGTACCCGATCATCAGTGGTGAGTTAACTTTCTTACCGAGCTGCCGCCCGTAAAAACCGGAAACAGTCTTGCCGCATTCAGCAGCCCTTTTCTGATTTCCTGGTCTTCTTCTGCCGTCAGACGAACAGGGTGACTGATAGCCCGCCTGCGTATTACTTCCACTTCGTTTTGTCATAAAACATGGCTCCGTATCTGGCATGGGTGTCAGGGGCAAAGCCTGACAGGGCAATTTGTAATAGCGTGCATGTATGCGCGGTATAACAATTGCACATCACACCAATCCTGTCAACAGCTCGAATTACCGACAAGGCACAGCGGTTTTGGCAGTGACGGTGTTGTCGGTCGGCAAGAAATGCCCATCAAGCCAAGCGGCAGAATAACAGCAGCAAAACAGTCGAAAAGTGGTACACGATATAATCACACAACGCAGATGACAGACAGAACGGAGAAAACGAAAAGATGAACAAGCAGCGGCAAGCCGTACTCAACATGGCGGGATTCATAAAGTCAGAGCCTGACGCTGCTCGAAAAACTGGACGCACCCGATGCTGACGAACAGGCTGCCATGTGTCGAGAAGCTGCACACGAACTCGCAGAAGAACTCCAGAACAACATCCAGACACGCTTTGAAGTAGAAAATAGCACAGAGATAACGCTCAGGACAGGATGCCGAACGGCGCAACCGTATGGAGAAAATGTCACATAAGGCGCTCTTCCGCGCTTCCTCGCTCACACTGACTCGCTACGCTCGGTCGTTCGACTGCGGCCGAGCGGTGTCAGCTCACTCAAAAGCAGTAATACGGTTATCCACAGAATCAGGGGATAAAGTCAGAGAACATGTGAGCAAAAGCAAAGCACCCGGAGGGAAGCCAGCGCCGCGACGTTTTCCATGACCGCCCCCTGACGAAACATCCTCACAAAAATCGACGCTCAAGCCAGAGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGTGTTTCCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTTCCGACCCTGCCGCTCCCCCGCCGGATATGTCGCCTTTCTCCTTGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAGTTCGGTGTAGGTCGTTCGCTCCAAGCTGGGCTGTGTGCACGAACCCCCGTTCAGCCCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACAAAGCGCCACTGGCAGCAGCCATTGGTAAAGTCGATGTGCGAGAGGTTCAAGAGAGTACTTGAGTGATGGCCCCTGACTACAGCTACACTGAAAGGACAGTTTTGGTGACTCGTCTCGCACAAGTTACCTGGTTAAACCAGTTCCCAACTGACTTAACCTTCATTCAGCTCACCTCCCCAGGTGGTTTTCGTTTTCAGTTTAGGAGATTACGACCAGAACACAATAAATACAAGAAGAAACTCCGACAAACTGGTTAAAATCAATCCAAACAGGACTATAAAGTAATATTATTTGATTATACTTCTAGAAAAGAAACAGTGGCATAGTGATGCATAAATAAACACATTATTACTATGTAAACGTAAACAGAAATGGAAACAAGTTTAAACATGATAAAAAGATATCCACTTAAAAAATTTTAGGAGTGTTTCGAGAGTATGCTCTCCAAACAACTAAAAACACTTAATGTAATATCCGGAAAAAACAACTTTGGGGAAAACAGCATCGATATTAAGACGCGATATTTTCTGTTTATGACGTAAAAAACCCAGCAGCTCTGTTAAAAGTAAAAACTTAGAAATGAAGCATCTCTTTTAAATAAAGAAAACTCATTTTGGGATAGCTAGCGCATAACATGGACACATCAAAGAAATGTCCATAATAAGAGATGAAAGGTCAGAAGTAGCTTACAAAAATACTCAACGATAGATAACACACCTGTCTCTTATACCCACATCTGACGCTGCCGACGACAGAAGGTGCGCGCGCAACAATACGTAAC
-+
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
-@bbb24ff0-9288-4eaa-b936-754d014b72aa
-CATTGTGCTTCGTTCAGTTACGTATTGCTGCGCGCACTCTCTGGTCTCGTGGGCTCGGAGATGTGTATAAGAGACAGATCTATCGTTGAGTATTTTGTGTTACTTCTGACCTTTCATCTCTTATTGTTATGGACATTTCTTTGGATGTGTCCATGTTATAAAAAATAGCTATCCCAAAATGAGTTTTCTTTATTTAAAGAGATGTAGAACAAAGCTTTTACTTTTAACAGAGCTGCTGGGTTTACGTCATAAAATGAAAATATCGCGTCTAATATCGATGTTTTCCCAAAGTTTCCGGATATTACATTAGGGTGTTTTTAGTTGTTTGAGAGTTATGCTCTCGAAACATAAAATTTTTAAGTGGATATCTTTTATCATGTTTAAGCTTGCTCTCAGCGTTTCTGTTTACGTTTACATAGTAATAATGTGTTTATTTATGCATCACTATGCCACTGTTTCTTTCTAGAAGTATAATCAAAATAACATTACTTTATAGTCCTGTTTGGATTGATTTTAACCAGTTTGTCGGAGTTTCTTCTTGTGATTATTGTGTTCTGGTCGTAATCTCCCTAAACTGAAAACGAAAAACCACCTGGGGAGGTGGTTTGATCGAAGGTTAAGTCAGTTGGGGAACTTGCTTAACCGGGTAACTGTCAAAGGCGAGTCACCAAAACTGTCCTTTCAGTGTAGTCCAGGCCATCACTTCAAGTACTCTCTTGGAACCTCTCGCACATCGACTTTCCTCTGTGGCTGCTGCCAGTGGCGCGCATCGTCTTACCGGGTTGGACTCAAGACGATAGTTACCGGATAAAGGGCGCAGCGGTCGAGCTGAACAGGGGTTCGTGCACACAGCCCAGCTTGGAGCAGACGATACCGCGAACCAGATACCTACAGCGTGAGCTATGAGAAAGCGCGCCACGCTTCCCGAAGGGAGAAAGGCGGACAGGTATCCGGTGGCAGCAGGTCGGAACAGGCGCACGAGGGAGCTTCCGGGGAAACACCTGGCGATCTTTATAGTCTGTCGGGTTCGCCACCTCTGGCTTGAGCGTCGATTTTGTGATGCTCGTCGGGGCAGGCCTGCTGGAAAAACGCCTGCGGCGCTGGCGCCATCCGGTGCTTTGCTCACATGTTCTTTCCGACTTTATCCCCGATTCTGTGGATAACCGTATTACCGCTTTTGAGCACCGCTCGCCGCAGTCGAACGACCGAGCGTAGCGAGTCAGTGTGAGGAAGCGGAAGGGCCTACCTGTGACATTTTCTCCTTACGCTCTGTTGTGCAGTTCGGCATCCTGTCCTGAAGCGTTATCTCTCTATCTTCGCCAAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTGCAGCTTCTCACACATGGCAACCTGTTCGTCAGCATCGGGTGCGTCAGTTTTTCGAGCAGCGTCAGGCTCTGACTTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTCGTTCAGTTTCTCCGTTCTGTCTGTCATGCGTTGTGTGATTATATCGCGTACCACTTTTCGACTGTTTGCTGCCGTTATTCTGCCTTGGCTTTTTGACAGGCATTTCTGTCAGACAACACTGTCACTGCCAAACTGCCGTGCCATTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCATACATGCGCGCTATTACAATTGCCCTGGTCGGGGCTTTGCTGTTTACCCATGTCGAATGCGGAGCCATGTTTTATGACAAAACGAAGTGGAGTAATACGCGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACGGCAGAAGGATCGAGAAAAGGGCTGCTGAATGCGGCAGAACCGTTTCCGGTTTTACGGGCGGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCGGGTACTGAAAGAGATTATGAGACTGGGGGCGTTGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGGAGTATGCGAATCGCTATTACGGGTGCGTGCCCTGTTATCCAGACTTATGGCAGATCGCTTCCCGGAGAGAAAACTGTCAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCATATTCCAGCGCCAGTGTGTGAGCGAAAACGATCTGACGCATCCCCTTCCTGTTTTCCCGAGGTAAAAACATCTCTTTTGCAGTTGTCTGGCGTCAGGAATCGCGTTCAGCGCGTTTCAGCGCTGATGCGTACAATTACAGCATTATGCTAATCTCTCTTGCCGCATCTGACGCTGCCGAC
-+
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
-@6ec80279-cd98-4039-b37a-aee0e098e4ac
-CTGCGTGCTGGTTCGATTCCCAATGTTGCTGCGCGCACCTCTGGTCGTGGGCTCAGATGTGTATAGACAGCCGCAAAAAGAGAATGTTTTGCAGAAAACAGGAGATGCGTAGGATCGTTTTCAGCTTTCGCAAGCGCCATAAGGTGAATGGTGATCACTTTGGGAAGAATTTCATACCGTCTGTTTTCGCCAGTTTTCTCCGAGCTAATCTGCCATAAGTCTGGATAACAGGGCACGGTGATACCTTTCCGTAATAGCGACACCTCCATACTCCCTGTCCCGAAACACGCTTGCCGTCGAAAAGTTTTCTGTAACGCCCCAGATCTCACTTCTTTCGTACCGAATCAATAGTCGAGTGAGTTAACTTTCTTACCGGCTGCCATGATAAAAAGCCGGAAGAATGCTTGCCACTAAACATTTTTTTTCTGATTTCTGGTCTTCTTCTGCCGTCAGACGAACAAGACGACTAGATCGCCCGCCTCTTCCACTTCGTTTTGTCATAAAAACATGGCTCCATTATCTGACATGGGTGTCGGGGCAAAACCTGAACGGTAATAGCGTGCATGTATGCGCTGGCAATTGCATCGTCAGCAAGCTCAATACCGACCATGCGCGGTTTTTGCTTTGGCAGTAATAGTGTTGTCGACAATGCCCGTCAGTGCGCAGCAGCAAAACAGTCGAAAATTGACACTGATATAATCCCACCTAGCGCGGATGACAGACAAATTGGAAGAAAACGAAAAGATGAACAAGCAGCACTCAACATGGCGGGGATTCGCCAAAGTCAGGCTGACGCTGCTCGGACGCACCCGATGCTGAACGGGCTACCGTAATGTGAAATGCACGGGCTTGAAGCTCCAGTGTATCCAGACACGCTTTGAAGTAGAAAATGGCACAGAGAGAATGCTTACGCTCGGGACAGGATGCCGAACGGCGCAACCAGAGCGTAAGGAAAATGTCATGGGCGCTCAGCACCACTTCCTCGCTCACTGACTCGCTACGCTCGGTCTGGAAGCTGCGGCGAGCGATTCGGCGCTCTCAAAGCAGTGGCCGCGGTTTATCTACCACTGGAACCGGGGGACCAGTCGGAAGAACATGGAGCAAAAAACGCCTGTGGAGAAGCCGAAGCGCCGCAGGCGTTTTCCATGGCTCCGCCCCTGACGAAACATCCTGAAAAATCGACGCTCAAGCCAGGGTGGCGAAACCGACATAAGATACCAGGTGTTTCCTGACTCCCTCGTGCGCTCTCCTGTTCAGGCCTGCCGCTCTTACACCGGTTCTCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCGCTGTAGGTATCTCGGTTCGGTTGTGGATAGTTCGCTCTGGGCTGCGGGCGAACCCCGTTCAATGACCGCTGCGCTATCCGGTAGCTCGGGTCAACCCGGTAAAAGTTACGAACAAAGCGCCACTGGCAGCAGCCATTATTGTTATCGATGCGAGGTTCAAGAGAGTACTGAAGTGGCCTGACTACAGCTACACTGAAAGGACAGTTTGGTGACTCGTCTCGCACAAGACAGTTACCTGGTTAAGCAGTTCCCCAATGAAGCAACCTTCGATCAAGCTCCACCTCCCCGGGTGTGGTTTTCGTTTTTAGTTTGGAAGTGCGACAGAACACAAATAATATCACAAGAAGAAACTCCGACAAACTGGTTCAAAAATCAATCAAGCTGGGACTATAAAGTAATATTATTTTTAGTTATGCACTTCTAGAAAAAGAAAGCAGACAGCATAGTGATATAAATAAACACATTATTACTATGTAAACGTAAACGAAATGGAGAGCAAGTTTAAACATGATAAAGATATCCATACTTAAGTGTTTCAGTATAACTCTCAAACAACTAAAAACACTTGAAACATCTTAATATCCGGAAAAAACAACTTTGGAAAATAATCGATATTAGACTTTGATATTTTCATTCATGACGTAAAAAACCCAGCAGCTGTTAAAAGTAAAGCTTTGAAAATGAAACATTATCTCTTTTAAATAAAAAGCTGGATAGCTATTTACTTTTAACAGAGCTTCACTGTTTAATAATGTCGCATTGTTCTTTATGTACATTTGTTGTGTTAAGCTATTGGGAGCATTTATATGTGGAAATTTGAAGGGGAGATAGCCAAGTATTTGTATATCCTTTCAGTGTGGCACCTGGTGGCCTCTCCACCTCTCTGCCATGTATCTTAGGATGTCCCATTGTGATGAGTAGTCTACAACATCTTTA
-+
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
-@e70c4558-0a68-4185-b45a-2bbe42130910
-CATTGTACTTCGTTCAGTTACGTATTGCTGCGCGCGCACTCTCTGGTCTCGTGGGCTGGAGATGTGTATAAGAGACAGCTTTTAAATAAAAGAAAACTCATTTTGGGATAGCTATTTTTATAACATGGACACATCAAAGAAATGTCCATAACAATAAGAGATGAAAGGTCAAGTAACTTACAAAAATACTCAACGATAGATAACACACAAAGTGAATCAAGCGTGTCCCTCAATGTTGAGTCAACTGTATTATCGACACCCCCTCCATTGCAAACAAGCCCTCAGCTCTCAGGAAAAAGGAATGTTTTAATGAGATTAAGGTTAGTGAAACACAGAACTGGAAAAGAACCCCCAGAAGAATTAGTTACTATAAAAATAACACAAAAAGCACAAGAAATAAACGAGGAAAATAAAACAAACTAAAAAGGTAAGCTATATGAATTCAAAACCATGTGATAATAACCACGTAAGAAACATAAACAAAGAAGCAACGATAAAAAACGTATCAAAACTACTAACACAAAAAAGAAAAGTGAAATAATGAGGCAACCTAAAAAGAATAGATAATAGAATTAACGATATTGCAATAATAGCAACCAGATCAAAACAAGAAGATTTTTTAGATATAGGACTAAGTGAATTAAATGAAATATCAATGCTTGGTGAAGGTAAGCAGAGCGCTGTCTTTCATTAGCTCAATCTTAGTTCAAAAGACTCAATTATTCTCATTGATGAGATAGAAATGGAAATTCATTACTCAGTAATCAAAGATATGATCAACGCTTTGATGAAGCGTGAAACCAATGGCAATCAAATATTTACAACAACACACAGCCATGATGCCAATATGTACGATAAACAGATTAGATGAAAAAGAAAGATATATCTTACGCCAAGACTGGGAAGAGACAAGAATCTCCAAAAACCTACAGCAATGCAATTTAACATGAATGATTTTTCTTTTCAGTTGAAAATGGCTAGGAGGTGAGGATATAAAGCTGAAACCGAGAAAAATAAATGATTATAAAAAAAGTGTTTTTCGTTGAGGTGATGATGATTTTCCTTCCTTTGCAATCTACTTGAAATGAAGGAATTAATGATGTTTATGTTGAAAAATAAATGGAAAGACAAAACTAAAACAAACCCTTAAGAGCCATTTAAAAGCATAGAGTCTTTTAATGAAAAAGAAATATATTCTTAATCATCGATGCCGACAAGTCGTTTTCTACTGACACGGAAGAGATCCGAGTAATTTCAACATTAAATGAGCTTAACATTTCATCCGCAAGCTCACCTAGCCAAAATACTAGCCATTAACAGGAAAAAATATTTCTTTATCATGCCAGGGAAAAAAAACAAGAATGGCGCAATAGAAGATCTAATCATTGCTCACGCGTGTAAGAAGGGTGTTTAGATATATAGACGATCTATTCAATAAAATAAAGAACAAGAATCTATTATTACGCATCCTTAAGATCCTGATTACACGCTTACCCAAATAATGAAAAGAAAGCAAAGGGATTCAAGTTTGCCTTAGTTGTAATAAGAGTCAAATTCTAGAATGAGCATATCAATGAAGAACAAACCGACGAACCTGGCGATGACTGCTTCAGTGAGATAAAAGAATTTATAATAAAATATGAAACAACTCCACCTACAAAATCAGCGCAATGACTAAAGACAATTATAAAATTTAACATAATGCTGTAATTGTACGCACCGCTGAAACGCGCTGAACGATTCTGGCACCAGACACCGCAAAGAGATATTTTACCCCGGGAAAACGGGAAGGATGCGTCAGGATCGTTTCATCGCTGCATAGCTATGCGTAAAAGCGGAGAAAGTGATCACTTTGGGAGCTTACGGTGTTCATACCGTCTGTTTTCGACTTCGATTTTCTCTCGGGAAGCTAATCTGCCATAAGTCTGGATAACAGGAGCACGGTGATACTCCGTAATAGCGATCAGCACACCTCCGCATACTCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTCTGCAACGCCCCCAGTCTCATAACTTCTTTTCGAGTACCCGATCATCAGTCAGTGAGTTGCTTTCTTTTTCCGAGAGCTGCCGCCCGTAAAAAACCGGAAACAGTCTTGCCGCATTCAGCAGCCCTTTTCTGATTCTGGTCTTCTTCTTGCCGTCAGACGAACAGAGAAGGGGCGACTGTGATAGCCGCCCTACCTGCGCGTAATACTTCCACTTCGTTTTGTCATAAAACATAGCTCCGTATCTGACATGGGTGTCAGGGTAGAAGCCCTGATCAGGGCGGTGTAATAGCGTGCATGTATGCGCGGTATAACAGTGCACATCCTATCCTGTCAGCAAGCTCGAATTACCAAAACAAAGGCACGGCAGTTTTGGCAGTGACAGTGTTGTCCTGACAGAAATGCCCGTCAAAAAGCCAAACTATGCCAGAATAACGGCAGCAGCAAAACAGTCGAAAAGTGGTACGCGATATAATCACCACAACGCAGATGACAGACAGAACGGGGAAAACGAAAGAAAGATGAACAAGCAGCAGCAAGCCGTACTCAACGCTGGCGGGATTCTTAAAAGTCAGGGAGCCTGACGCTGCTCGAAAAACTGGCGGACACTTTTTGATGCTGACGAACAGGCTGCATGTGTGAAGCTGCACGAACTCGCAGAAGAACTCCAGAACAGCATCAGACACGCTTTGGAAGTAGAAAATAGCACAGAGGAGATAACGCTCAGGACCGGGATGCCGAACGGCGCTGTAAGGCAATAAGGAAAATGTCACATAAGGCGCTCTTCCGCTTCCTCGCTCACTGACTCGCTGCTACACGCTCGGTCGTTCGACTGCGGCGAGCGGTATCAACTCACTCAAAAGCAGTAATACGGTTATCCACAGAATCGGGGATAAAGTCCGGAAAGAACATGTGAGCAAAAAGCAAAGCACCGGAGAAGCCAGCGCCGCGAACGTTTTTCCGCGAAGCTCCGCCCCCTGACGAACATCCCACAAAAATCGACGCTCAAGCCAGAGGTGGCAGGAAGCCCGACAAGGACTACTAAAGATACAAGTGTTTCCCCCTGGAAGCTCCTCGTGCACTTCTCCTGTTCCGGCCCTGCCGCCCACGAGATACCTGTCCGCCTTTTACTCCCTTCGGGAAGCGTGGCTTTCCTCACCAGACTCACGCTGTAGGTATCAGTTCGGTGTAGGTCGTTCCGCTCAAGCTGAGCTGTGTGCACAGACCCCCGTTTGACCCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTCAACCCGGTAAAGGGCACGACAAAGCGCCACTGGCAGCGGCGGCTGGTAAAAGTCGATGTACGAGAGGTTCAAGAAAGTACTTGAAGTGATGGCCTGACTACAGCTACACTGAAAGGACAGTTTTGGTGACTCGTCTCGCACAAGACAGTTACTATAGTTAAGCAGTTCTAACTGACTTAACCTTCCTTGATCAAACACCTCCCCGGGTGGTTTTGGAATTTCAGTTTAGGAGATTACGACAGAACACAATAATCACAAGAAGAAACTCAAACAAACTGGTTAAAATCAATCAAACAGGACTATAAAGTAATAATATTTTGATTATACTTCTAGAAAAGAAACAGTGGCATAGTGATGCATAAATAAACACATTATTACTATGTAAACGTAAACAGAAATGGAGAGCAAGTTTAAACATGATAAGATATCATAAAAAATTTTAAGTGTTTCGAGAGGCATATAACTCTCAAACAACTAAAAACACTTAATGTAATATCCGGAAAAAAAAACAACTTTTTGGGGAAAACATCGATATTAGACGCGATATTTTCATTTATGACGTAAAACCCAGCAGCTCTGTTAAAAGTAAAAAGCTTTAGAAATGCAAGCATCTCTTTTAAATCTGTCTCTTATACACATCTCCGAGCCCACGAGACCAGAGAGAGTGCGCACGTAGTACGTAATAAATAAC
-+
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
-@954e92c6-9688-4242-bcf6-16087a6e4cbb
-CGGTAGCCGCTGGACTAGTTGTATTGCTGCGCGCACTTTTTCATGTCGTCGGCAGCGTCGAATGTGTATAAGAGACAGATATTACATTAAGTGTTTTTAGTTGTTTGGAGGTTAGCTCTCGAAAGCCTTAAAATTACACCCAAAGTGGATATCTTTTATCACGAACTGACTTGCTCTCATTTCATTTTGTTTATAGTAACAATGTGTTTATTTATGCATCACTATGCCACTGTTTCTTTTCTAGAAGTATAATCAAAATAATATTGTAGTCTGAACTGAGTTGATTTAACCAGTTTGTCGGAGTTTCTTCTTTATTTGATTACATTGTGTTCTGGTCGTAATCTCCTAAACTGAAAACGAAAAAACCACCTGGGGAGGTGGTTTGATCGAAGAGTACTAAGTCGGTTGAGGCACAGCGGCAGGTATTATCTTGTGCGAGACGAGTCACCAGGCTTGTCCTTTCCAGTGTAGCTGTAGTCAGGCCATCACTTCAAGTACTCTCTTGAACCTCTCGCACATCGACTTTTACCAATGTGCTGCCAGTGGCGCTTTGTCGTGTCTTACCGGGTTGGACTCAAGACGATAGTTACCGGATAAGGCGCAGCGGTCGGGCCGAACGGGGGTTCGTGCACACAGCCCAGCTTGGAGCGAACGACCTACGCCGACCAGATACCTACAGCGTGAGCTATGAAAGCGCCACGCCCCCGAGAGGGAGAAAGGCGGACAGGTATCCGGTAAGCGGCAGGAGTCGGAACAGGAGAGAGCGCCGAGGAGCCCGGGAAACACCTGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTCTGGCTTGAGCAATCGATTTTGTGATGCTCGTCGGGGGCGAACCTATGGAAACGCCTGCGGCGCTGGCTTCCTCGGTGCTGCTTTTTGCTCCGTGAACAATCAGGCTTTGTCCACGATTCTGTGGATGGCAATGTTAGCGCTGGGTGAGCTGGTACCGCTCGCGCAGTCAGACGACCGAGCGGCAGCGAGTCAGTGAGCGAGGAAGCGGAAGAGCACTATATCTGAGCATTTTCTCCTTACGCTCTGTTGTGCCGTTCGGCATCCTGTCCCTGACGTTATCTCTCTCAATGCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTGCAACTTCTCACACATGGCAACCTGTTCGTCAGCATCGGGTGCGTCCAGTTTTTCGAGCAGCGTCAGGCTCTGACTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACATTTTCGACTTTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTGACGGGCATTTCTGTCAGACAACACTGTCACTGCCAAAAAACTGCCGTGCCTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCATACATGCACGCTATTACAATTGCCTGGTCGGGAGCTTTGCCCCGACACCCATGTCAGATACGAACCATGTTTATGACAAAACGAAGTGGAAGTAATACGCGCAGGCGGGCTATCAGTCGCCCTGTTCTCATGACGGCAGAAGAAGACCAGGAAATCCCAGAAAGGGCTGCTGAATGCGGCAGAATAACCGTTCCAGTTTTACCAGGGCGGCAGCTCTCGATAAGAAAGTTAATACTGACTGATAGTCGGGTACTGAAAGAAGTTGTAAAGGACTGGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGGTATGCGGAGGAGTGCTGATCACTTTATTACGGAGTATCACCGTGCCCTGTTATCAGACTTATGGCAGGTCGGCTTCCCGGAGAGAAAACTGTCGAAAACAGACGGTATGAACGTGTCCCAAAGTGATCACCATTCGCTTTCATGCATATGTATGCAGCAGGCTGAAAACGATCTGACGCATCCCTTCCTGTTTTCCCCAGGGTAAAACATCTCTCTTTGCGGTGTCTGCGTCAGAATCGCGTTCAGCGCGTTTCAGCGGTGCGGCCTACAATTACAGCATTATGTTAAATTTTATAATTGTCTTTAGTCATTGCGCTATGATTTTGTAGGTGGAGTTGTTTCATATTTTTGATATAAATTCTTTTATCCCACTGAAGCAGTCATCGTCAGTATCAATGGTTTTTGTTCTTCATTGATATGCTATTCTAGAATCTGGTTCCTTATTACAACTAAGGTAAACTTGAACTTTCTGCTTTCTTTTCATTATTTGGGTAAGCGTGATAAGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTTATTTTGTGAATAGATCGTCTATATATCTAAAGCCTCTTTCTTACACGCGTGAGCAATGGTTAGATCTTCTATTGCGCCATTCTTGTTTTCTGGCATGATAAAGAAAGATATTTTTGTGCTTCCGTTAATGGCTATTTCATTATGCGAGCTTGGTGATGAAATGTTAAAAGCTCATTTAATGTTGAAATTATCGATCTTTCCGTGTCGAAAACGATTCGTCGGCATCGATGATTAAAATATACTTTCTTTTTCATTAAAGTTTCTATCTTTTAAATGCTCTGTAGGGTTCTTTAGTTTTGTCTTTCCATTTATTTTTCAACATAAACATCATTAATTCCTTCTATTTCAAGTAGATTGCAAAGGAAGTGAAAATCATCATCACCCTCAACGAAAATGACTTTTTATAATCATTTATTTTCTCGGTTTCATTTATCTCACCTCCCAGCCATTTTCAACTGAAGAAAAATCATCCATGTTAAATTGCATTGCTGTAGGTTTTGAGATTCCTTGTCTCTTCCCAGTCTTATGTAAGATATATCTTTTCTTTTTCATCCTAATTCGTTTATCGCACATATTACATCATGGCTGTGTGTTGTTGTAAATATTGATTATTATTAGTTTTTGCTGCTTCTATCAAAGCGTTGATCATATCTTTGATTACTGAGTAATGAATTCCATTTTCTATCTCATCAATGAGAATAATTGCTGTCTCTTGCCCATCTGTTTGCTTTGCAAACGACAGAGAGTGCGCCTTGCAACAATACGTAAC
-+
-,(-,,&%'%#'$%$$'$%0(%%&-3'+3670-(&##$$%&+%#(+;>64;062.<<;64$$-$(,/(%7/0*.046489;7<922127675@B<=GE@6;=>:A@<'($$0,*%%$)-25&&(*$'("%'+*'&*#$$#''/0/-503:@>;>KHF=850#%((&%&&#$$%&(/--12:=4)#&,&&%%-'')),)&&%*)$$'&/2/4>@=82/065:0/:95331-,68>=G:RIMEA6F0I>GE?C2677AB8?8354463#%%)+*''%%"$%%3',&%+/,.,+7;?DBM6.=+/+=HHC=C=765*$$&+))6-%$'1558>?<A4012*#),29=>367HI<9998C<0-$%'//10446;;2+-4-*+2;89BI@G/'>64-,$*-%((--*%;(-5,1$&+,+*'()$*.%()&&#&#%&&0/@62()<8652:1>/..'&($%451191;A.63;C=>=<:99533/4+*(;<:3?:9A8G<=8ECA>898:6:0/,,398:,179;:;;=@JFJD?B?00/)179A?A@>;F?B=?--/C?<A>GA=@A;@NI78EJCABDEGE@AC?9664-B>@CEA?AC@FG,9C;<B78@>3***-%$)(2=&-;:B;:4/F@;:6=FBE?E;:;33326&2.%$)9?<:7&(1&((&&'+$&:56==2.+'-/31::<DCB:420+.3(+)%'')+-2'($''<5.;.&0%4<=/4=/)*,><//>=>;:;AEFH84>%%<5@@DGD83?5;-&)&97/%+'$20+/%&&&)'),'2-865*/7::@CFCA1,8-.0B?8?-.EBBB;'''&+,26-&($$$+*&.$&&*$$%)<<4=B>H4)B</(<$-403..%%89:*&,---+-.==<:8?DDHEAGH?@?<=5A67;%$<7344542'%)$''+)&'$###%%'()*,-'%%&%5====@90,*,*,#$.%%(%-(%%'$$))+01+*&&$$%##%)'--8*.-*(-19&&209<?4,(63%'%0)/0/:7>,/7<241,++-(2/43435*/)12-'&53(&%-).9>@CLE@A6>8;<DHI<BE>LI:@??@=D>*1=H;,,.>;77<655%/95>>8:5+6.*&'(&'.1.2:BB:1,45/:BB(4=6C;6?;./34+9:>=.A/9;-3>BCD@D>A<>:CBC4.<15&&"$,$%)+*-6/JAHH*+@@KCABB/,@D8D;9C9=:510;))>4?9<JI/5+''&(#>>9=57:B,>*A>330,)/0+))8;@=BIEICEID=;ACBC2:ESQB/6C9997=@CEDF=BDGDJ>5>OIND??8<4D>@77?AAC>BB>D>:@:JD*A:9A?9<BBE@E=:;86:$00=@@87%%'<8GFJL@EI;*,'+/':>;<.14.%%%59677GD>;8:))*A@CCKD@82<%&:887?C>>($B$$79-3==8990'-.598D2,,&2@4/:'(+$-@@1%$*=?C<@:F88-=CG70=??A(6'((('+279><<@A9BHH@985:66./>22@>?@=A>?7:ABAB:8%%&)+&2AIIG;BDF@:77=GE?E@A94-0221((#&581.2BAAEECEEBCFA40.81?EGE;ACDGBEF'6F>><CA./=@@=65+;6<;<:22225=8&#-2-('(-.):2),(>@82,-*32/''2*,)30)'04*@<=8AAE=/5&''*$$-'''.06@;)-%5-29/**1'.19>++'&,571+''(0&&&))(2;>3-*%..725,0'$((06)++5213:9;%'++==;$$$)-,41798=51+-,'+'&&'&*985;?B<@AEGCAEGF3>B=?=ABI3+>,147:5)-+,-?;:A5,/#$#7<:;11.+7$$$'7322)</6*:>+'5+-)465;8:??>>-'@=;BAG9B@23.-)$'&'/;>:<=89<==8*7AA<:B94@7:B?.2.6.C39>:4))&&$%#%&&&''(.><6-2,13:;3=%$>??>;@>=??>233::@50:9**B;<CCGG>>@/'B)A>C3=4,,4.-3';DEEGK@39>%%7322DF?E@30.2.;7,/<7=06<624*531)%#'.6:?CGCGBC@?<.AALI:45+(%,-')%&'&#),*+*+6?C:A78>C=CJC35:<60,:ADJDJC>?PJ?BD=?=?A;-9:EIAB?AJNK@D>;;;79365:=>?KAFDEG?GDEDE<42-48;;1//./2;<?@@7521,%62:663;<0*5--730<A>?8<;=:73%-08E@<@?E?:;:++4(57)=-42--&9(;<ID44,D@@A>ADB=>@A7A@EF>BF@=9:<??<$(()45C;>@?0'*/5/46766=<<>850.%%%%'79====816IFFCE@GE@B>@;AA?BBDABB@FFF<22264(978A:F3A??30-1:<=650;)01,%(+068A<@>?.,/.5=;CFAD?983+.1+8)@:=?C==66<>1EBGFDEAII?CAI3@/4695==@;HN@/9:--GKFIDHGE7E;;>?9;;JD>?C@A>8++-DA4>@??>@==:==<.4;==<652H:=AD>?3)=C>A787169))?,&.:;:>?>EDF;=HDD991@/*3,-,(,?>@@@@>:??DHGBD;:B@<>8&'(5;0***3<FCFCIFEE;<;11*%#%+&%,,*+=F==?A77@@5,%%&)5=C@('73-8.<HGB;<EBF<@DHIIBDBFB;:102-79:54CAACGFHHGD:;BADGAFF@:69>521()63<AA(*713*512DBE>@A@@><:BFE;>=75545HDC8=*%87764?C@A<AEKKKGDALG@/>'.EFH<=@>B>;=?A;=;A&>9>:;=?@?I+>;2,31/*&571,54;634=CBEDA2400;5:<BC9>;<12./=<MGCA=AG@8:7AECHCBJD<=CAA=?HI?9ABCD>:;971**46>=9>7BC@AB%%);@B@B<8EEA4,5'(*+<BB>3*-(.8>F>B>A>0C>CC@4EGBB@C8//869-747-/3<;2>?=JGD;;G<7:<F?B:>BC@/:35/+)'3)/796<EEECI:1>=@6?:..022/HD8=@CCP?A>?9;&>C<IIK@EE@?EC-.,04=;9=?7?;0(&$%'),$$%'(&%&'%$$&*)*9?7;30(''+((*')'*09))320)'+/1++,
-@8d219e27-0a05-49c8-a43b-146db9eabc24
-CAGTGTACTTCGTTCGTTGTATTCTGCGCACGCACTCTCTGTCGTCGGCGTCAGATCGTATAAGAGACAGGCACAGAGATAGCGCTCAGGACGGATGCCGAACGGCTGAAAAGCAGAGCGTGGAGAAAATGCCGCCAAGGCGTCTTCGCTTCTCTAACTCACTGCAAACTAACTGCATCGGTCGTTCGACTGCGGCAGAGGAAGCGGTGTCAGCTCACTCAAAAGCGGTAATACGATTATCCACAGAATCGGGGATAAAGTCGGAAAGAACATGTGAGCAAAAAGCAAAGCACCCGGAGGAGAAGCCAGCGCCGCAGGTTACCGCTGACTCCGCCTGACGAGCATCACAAAAATCGACGCGCTCAAGCCAGAGGTGGCGAAACCCGACAGGACTATAAAGGCTTGGTGTTTCCCCTGGAAGCTCCCTCGTGCACTCTCCTGTTGACCCTGCCGCTTGCCGGATACACCTGTCTTTCTCCCTTCGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTGGTATCTCGGTTCGGTGTGGGTCGTTCGCTCAAGCTTAGATGATGCACGAACTACCGTTCGGCCCGACCGCCGCCTTATCGGTAACTATCGTCTTGGGTCCAACCCGGTAAGACACGACAAAGCGCCACAGCGGCAGCCACGGTGGTAAAGTCGATGTGCGAGAGGTTCGAAGAGTACTTAGTGATGGCCTGACTGGCTACACTGAAGAAAGGACAGTTTTAGTGACTCGACCTTCTTTAAGACAGGTTACTGGTTAAGCAGTTCCCCAACTGAAGCAACAGCTGATCGACCCACCTCCCCAGGTGGTTTCGTTTTCAGTTTAGGAGATTACGACTGAACACAATAATCTAGAAGAAACTCCGACAAACTGGTTAAAATCCAATCAAACAGGACTATAAGTAATATTATTTTGATTATACTTGAAAGAAACAGTAGCATAGTGATGCATAAATAAACACATTATTACTATGTAAACAATAAACGAAATGGAAACAAGTTTAAACACATGATAAAAGATATCCACTTAAA
-+
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
-@fcda25e8-3066-4ba5-8453-30d04908ccdf
-CGATAATCGCTACGTTCAGTTACGTATTGCTGCGCGCGCGCCTCTCTGGTCTCGTGGAGCTCGATTATGTATAAGGACAGTGTAAGTATTATACCAGTTTCTGATAACAAGACTTGCTCTCTCAAACAACTAAAAACACTTAATGTAATATCCGGAAAAAACAACTTTGGGAAAACATCGATATTAGACGCGATATTACTCATTTATGACGTAAAAAAAAACCCAGCAGCTCTGTTAAAAAGTAAAAAGCTTTAGAAATGAAGCATCTCTTTTAAAGAAAACTCATTTTAGGATAGCTATTTTTTATAACATACTGGACACATCCAAAGAAATGTCCATAACAATAAGAGATATAGAAGGTCAAGTAACACAAAAATACTCAACGATAGATAACACACAAAATTAGATCAAGCGTGTCCCTCAATGTTGAGTCAATATTATCAAACACCCCTCCATTGCGACAAACCCTCGGCTCTCAGGAAAAGGGGAATGTTTTAATGATTAAGGTTAGTGTAACACAGAACGGAAAAAGAACCCCCAGAAGGATTGATTACTATAAAAATAACACAAAAGCACAAAAATAAACGGAGAAATAAAACAAACTAAAAAAGGTAAGCTATGTGAATTCAAAACCGCAGCGATAATAACCACATCCAAGAAACATAAACAAAGAAGCAACGATAAAAAACGTATCAAAACTACTAACACAAAAAGAAAAGATGGAAATAATGGGCAACCTAAAAAAAGAGAATAGATAATAGAATTAACGATATTGCAATAATAGCAACAGATCAAAACAAAGAGATTTTTTTAGATATAGGACTAAGTGAATTAAATGAAATATCAATGCTTGGTGAAGGAGTAAACCCAGAGCGCTGTCTTTCATTAGCTCAATCTTAGTTCAAAAGACTCAATTATTCTCATTGATGAGATAGAAAATGGAATTCATTACTCAGTAATCAAAGATATGATCAACGCTTTGATAGAAACACAAAAACCAATAATAATCAAATATTTACAGCAACACACAGCCATGATGTAATATGTGCGATAAACAGATTAGATGAAAAAGAAAAGATATATCTTACATAAGACTGGAAGAGACAAAGGAATCTCAAAAACCTACAGCAATGCGATTTAACATGGATGATTTTTCTTTTCAGTTGAAAATGGCTGGGAGGTGAGATAAATGAAACCGAGAAAAATAAATGATTATAAAAAAGTCATTTTCGTTGAGGGTGATGATGATTTCACTTCCTTTGCAATCTACTTGAAATAGAAGGAATTAATGATGTTTATGTTGAAAAATAAATGGAAAGACAAAACTAAAACAAACCCTTAGAGCATTTAAAAGCATAGGAGTCTTTTAATGAAAAGAAAGTATATTCTTAATCATCGATGCCGACGAATCGTTTTCTGACACGGAAAGATCGATAATTTCAACATTAAATGAGCTTAACATTTCATCCGCAAGCTCGCATAATGAAATAGCATTAACGGAAGCACAAAAAATATCTTTCTTTATCATGCCAGGAAAAAACAAGAATGGCGCAATAGAAGATCTAATCATTGCTCACGCGTGTAGAAGAGGTGTTTAGATATATAGACGATCTATTCAATAAAATAAAAGAACAAGAATCTATTACATCCTTAGATCCTGATTACGCTTACCCAAATAATGAAAAGAAAGCAAAGTTCAAGTTTACGCTTAGTTGTAATAAGGAATCAAGATTCTAGAATAGGCATATCAATGAAGAACAAAACCATTGATACTGACGATGACTGCTTCAGTGAGATAAAAAGAATTTATATCAAAATATGAAACAACTCCACCTACAAAATCATAGCGCAATGACTAAAGACAATTATAAAATTTAACATAATGCTGTGGTGTACGCACCGCTGAAACGCGCTGAACGCGATTCTGACACAGACACCGCAAAGAGATGTTTTACCCAGGAAAACGGGAAGGATGCGTCAGGATCGTTTTTCAGCTCGCTGCGCTAGCTATGCATGAAAGCGAATGGTGATCACTTTGGGGAGCTTACGGTGTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCGGGAGGCTAATCTGCCATAAGTCTGGATAACAGAGGCACGGTGAAGTACTCCCGTAATAGCAGCGGTAGCACCTCCGCATACTCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTCTGCTTAACGCCCCCAGTCTCATAACTTCTTTCAGTGCGATCATCAGTCAGTGGAGTTAACTTTCTTACCGAGAGCTGCCGCCCGTAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCTTTACAGTTCCTGGTCTTCTTCTGCCGTCAGACAACAGGGCGACTGATAACCCGCCTGCGCGTATTACTTCCACTTCGTTTGTCATAAAAACATGGCTCCGTATCTGACATGGGTGTCAGGGCAAAGCTGACCGGAACGGTGTAATAGCGTGCATGTATGCGCGGTATAACAATTGCACATCCTGTCCTGTCAGCAGCTCGAATTACCGACAAAGGCACGGCAGTTTTTGGCAGTGACAGTGTTGTCTGACGAAATGCCCGTCAAAAAGCCAAGCGGCAGAATAACGGCAGCAAAACAGTCGAAAAAGTGGTACACGATATAATCACACAACGCAGATGACAGACAGAACGGAAAACGAAAAGATGAACAAAAAACGCTTAACAAGCCGTACTCAACATGGCGGGATTCATAAAGGGTAAGAGCCTGACGCTGCTCAACTGGACGCACCCGATGCTGACGAAGACAGGCTGCCATGTGTGAGAAGCTGCACGAACTCGCAGAAGAACTCCAGAACAGCTTCCAGACACGCTTTGAAGTAGAAAATAGCACAGAGAGATAACGCTCAGGACAGGATGCCGAACGGCTGGCAGAGCGTAAGGAGAAAATGTCACATAAGGCGCTCTTCCGCTTCCTCGCTCACTGACTCGCTACGCTCGGTCGTTCGACTGCGGCGAGCGGTGTCAACTCACTCAAAAAGCAGTAGCCACGGTTATCCACAGAATCGGGGGATAAAGTCGGAAAGAACATGTGAGCAAAAGCAAAGCACCGGAGGAAGCCAGCGCCGCGTTTTCCATAGGCTCCGCCCTGACGAGCATCACAAAAATCGACGCTCAAGCCAGGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGTGTTTCCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTCCCGACCCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCGGTTCGGTGTAGGTCGTTCGCTCCAAGCTGGGCTGTGTGCACGAACCCCCCGTTCAGCCCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACAAAGCGCCACTGGCAGCAGCCATTGGTAGAAGTCGATGTGCGAGAGGTTCAAAGAGAGTACTTGAAGTGATGGCCTGACTACAGCTACACTGGAAAGACAGTTTGGTGACTCGTCTCGCACAAGACAGTTACCTGGTTAAGCAGTTCCCCAACTGACTTAACCTTCGATCAAACCACCTCCCCAGGTGGTTTTCGTTCAGTTTAGGAGATTACGACAGAACACAATAATCACGAGAAGAAACTCCGACAAACTGGTTAAAATCAATCCAAACAGGACTATAAAAGTAATATTATTTTGATTATACCTCTAGAAAAGAAACAGTGGCATAGTGATGCATAAATAAACACATTATTACTATGTAAACGTAAACAGAAATGGAGAGCAAGTTTAAACATGATAAAGCATCTCTTATACACATCTCGAGCC
-+
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
-@d661f019-78e1-4c96-9aec-c8d4b7df233a
-AAAGAGATGTTTGCGGGAAAACAGGAAGGATCACGTCAGGATCGTTCTAGCTCGCTGCATGTAAGCAAGTGGAAATCACTGCAGGAGCTTACGGTGTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCGGAAGCTAATCTGCCATAAATGGATAACAGGGCACGGTACTCCGTAGTGCTTGATCAGCACCTCCGCATACTCCCTACTCTACCCGACACGCGCAGGTCGATAAAGTTTTCTGTAACGCCCCCAGTCTCAACTTCTTTCATTTTCCGATCGTGATCAATTGAAAGTTCATGCTTTGCCCACCAGGCTGCCTTCATAAAAGCTGAGCAGTCTTGCCGCATTCAACAGCCCTTTTTCTGATTCCTGGTCTTCTTCTGCGCCGTCAGACGAACTGAAAGGCGGCAGCTGATAATACCTTACGCGTATTACGCCCACTTCGTTTTGTCATAAAACACTTGGCTCCCGTATCAGCATGGGTGTCAGGAGCCACCAGAAAGCCCACGACCAGACACGAATTGCTAATAGCGTGCATATGCGCGGTATAACAATTACACATCCTATCCTGTCAATAAGCTCAATTTTAAACGAGGCACGGCAGTTTTTGGCAGTGACGGTGTTGTCTGACGAAATGCACCCGTCAAAAGCCAAGCGGCAGAATAACGGCAGCAAAACGGTCGAAAAGTGGTACGCGATGCCACCTATAATCACACAGCAACGCAGATGACAGACAGAACGGAGAAAACTGAAAAGATGAACAAGCAGCGGCGAAGCCCGTACCTCAACATGGCGGGATTCATAAAAGTCAAACCTGACGCTGCTCGAAAAACTGGACGCACCCGATGCTGACGAACAGGCTGCCATGTGTGAGAAACTGCACTGAACTCGCAGAACTCCAGAACAGCATCCAGACACACACTTGAAGTGAAAATAAGCACAGAGGAGATATAAGCATAGCGGGACAGGTGCCGAGCCTTTGTGAGCGCAAGGGAGAAATATCACATAACGGCTGCTCTCCTACGCTTCTACTCGCTCACTGACTCGCTGCGCTCGGTCGTTCGACTGCGGCGAGCGGTGTCGAAAGCTCACTCAAAAGCGGTATTACGGTTATCCACAGAATCAGGGGATACAAGTCGGAAAGAACATGTGAGCAAAAGCAAAGCACCGGAGGAAACCAGCGCGAACGTTTTCCATAGGCTCCGCCCCCTGGCCGAGCATCACAAAATCGACGCTCTGACCAGGGTGCGAAACCCGACAAGGACTATAAAGATACCGGGTCGCTTCCCCTGGAGGCTCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACGGATACCTGTCCGCCTTTCTCCTTCAGGAAGCGTGGCTTTCTCGCTGAAAAACTCACCGCATGCCGAAATTATCAGTTCGGTGTAGGTCGTTCACTCCAAACGTTTGTGCGAACCTACCCCATTCGAAGCGCCGACCGCTGCACCATATCAGTAACTATCGTCTTGAGTCCAACCCGGTAGACACGACAAAAGCACCACTGGCGGCAATACATTGGTAAAAGTCATTGAGAGGTTCAAGAGAGTACTGAAGTGATGGCCACAGCTACAGGCTTTACTGAAAGGACAGTTTGTGAGTGACTCGTCTCGCACAAGACAGTTACCTGAATTAAGCAGTTCCCCAACTGAAGCAACCTTCAGTGAAGCCACTCTCTACAGGTGGTTTTCGTTCAGTTTAAGGGAATTACGACCAGAACACAATAATCACAGAAGAAACTCCGACAAACTGGACAGAAGTAATCAAAACAGGACTATAAAGTAATATTATTTTGATTATACTTCTAGAAAGAAACAGTTAGCATAGTGATACATAAAATAAACAC
-+
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
-@d76c1db8-3831-466a-8924-8b70e756d631
-CGATGGCTGCTTCGTTCAGTTACGTATTGCTGCGCGCGCGCCTCTCTGGTCTCGGCGGGCTCGGAGATGTAAAGGAACAGACCCACAGCGCAGATGACAGACAGAACGGAAAACGAAAGATGAACAAGCAGCAGCAAGCCGTACTCAACATGGCGGGATTCATAAAAGTCAGAGCCTGACGCTGCTCGAAAAACTGGACGGCGCTTTGGTGCGACGAACAGGCTGCCGTAGCGGCAAGCTGCGAACTCGCAGAAGAACTCAGAACAGCATCCAGACACGCTTTGAAGTAGAAAATAGCACAGAGATAACGCTCAGGACAGGATGCCGAACAGCTGTAACAGAGCGTAAGGAGAAAAATGTCACATAAGGCGCGCTCTTCCACTTCCTCGCTCACTGACTCGCGCTACGGCGCAGTCGTTCGACTGCTGGCGACAGTGTCCGGCTCACTCAAAAAAGCGATGGCTTCACGGTTATCCACAAATCAGAGGGGATAAAGTCGGAAAGAACATGTGAGCAAAAGCAAAGCTTGCCGGAGGAAAACTAACGCAGTGAACGTTTTCTCCATAGGCTCCGCCCCTGACGAGGCATCACAAAATCGACGCTCAAGCCAAGTGGCAAAAACCGGAAGCGGACTAAGAATACCGGTGTTTCCCCCTGGGAAGCTCCTCGATGCGCTCTCCTGTTCCGACCCACCACTTACCGGATACACAGCTCCACTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTCGCATAGCTCACGCTGTAGGTATCTGGTTCGGTGTGGTCGTTTCGCTCAACTGTTTCGTGGTGCTGAACCCCGTTCAACCGACGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTTAACCGGTAAGACACGACAAACCACTGGCGGCAGCCATTGGTAAAAAGTCGATGTGCGAGAGGTTCAAGAGAGTACTTAGTGATGGCAATACGGCTGCGCTGAAAAGGACCGGTTTTGGTGACTCACATCTCGCCTGAATCCACTAGGGTAAGCAATTCCCCAACTGACTTAACCTTCGATCAAACCTCCTCCCAGGTGGTTTTTCGTTTTTTCAGTTTAGGAGATTACGACCAGAACATCACAAGAAGAAACTCCGACAAACTGATTAAAATCAATCAAACAGGACTATAAAGTCTGTCTCTTATAC
-+
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
-@e77471f2-2e52-417e-a96e-296eafd559d9
-CAGTGTACTTCGTTCGGTTACGTATTGCTGCGCGCGCGCTCTCTGTCGTCGGCAGCGTCAGATTGTGTATAAGAGACGGGGGCTGTATTGCACGAACCCCCGTTCAGCCCGACCGCTGCGCCTTATCCAGTAACTATCGTCTTGAGTCAACCCGGTAAGACACGACAAAGCGCCACTGGCAGCAGCCATTGGTAAAAGTCGATGTGCGAGAGGTTCAAGAAGTACTTGAAGTGATGGCCTGACTACAGCTACACTGAAAGGACAGTTTTGGTGTCGTCTCGCACAAGACAGTTACCTGGTTAAGCAGTTCCCCAACTGACTTAACCTTCGATCAAACCACCTCCCCAGGTGGTTTCGTTTTCAGTTGAGAGATTACGACCAGAACACAATAATCACGAAGAAACTCCGACAAACTGAAAACGAAAAAACCGCAGAGGAAGTAATTTGATCGAGGTGGGTCGGTTGAGAAACGCCCAACCGGGTAACAGCTCTTGTGCGAGACGAGGAACACCAAACTGTCGCTCGAATGTCAGCTATTCAGTGTCACTTCAGTACTCTCTTAGTCTCTCATATCATTTGCAATGGCTGTCGTCAGGTTGAACTCAGAACGTGGTTACATCGCGGCAGTCGATTCGTGTCTCTGCCGCGACTGCCATTGTGCGGCTGAAAATGCTGCAGCAATACGCTA
-+
-))$&++-;==,@I.>,2695AACEJJ7BGA8*33*,%%%17==/A<A=9@:B:6E)&&+&*%$,&'(48<$%9,.+:(+62?><400024512225CFTM@@I3A<>DDBCGDD:55*'($$&59%%1(=AA>?AC?D?A>01:2,$@77FJF?AB:;<E?.F<C8A@4:@CCC=DGAA9?1338@?==><@=55/%,9=?FHADD?;:)36FHB:*+$$$)<C?A@32*4B??F<DDDGJD@>63/CBD,-8;9>3H<22A-+7<;@9'+&&1339AA@?AEA@>:B3+8;=6:;2'+)0?A0@?ACCBIFE>>=@F@AF@9:FEIDA@=7;9918;463>9<?4*1,.-0154888)$'*%9**$$'/10/166966;@>:BF@;336:6.6%'&&',0:?>@6:9ACIKF?7756;B@**@MIE9==)'+%%&$(&%(%%(-0.-.07,,3/()(#%+.'*&%%$%$$%%%%,-,0%'()(()&,,2447:=30.((*.&&(($#%$%+*)(((&&+##'%%$$'$$$$$$'$%&%$%,'/1-%&'%($&&'(),2++%%$(*+0/$*,*.$%''$.(+6,00/,((%$)#(.'.436:80*)%)1)1%)%%%'%)*/2283,/+*$$*/-'0$,(0+,))(')*&)112.##$'#%'#$$%,-/0+#$%&*($$%*+**/'$%$
-@7f107a80-39f0-4be1-b37b-197c600773ed
-TAAACAGAAAAAAAAACCGCCTGGGGGAGGCGGACGATCAGGTTAAGTCAGTTGGGGAACTGCTTAACCAGCACGAGGTAACTGGCTTCCTTGGAGAGCGCAGATGCAAGCCACTGTCTTCCAGTGTAGCCGTAGTCAGACCGCTACTTCAAGAACCTGTTTGCACCATTTGCGCCATCATCGCTCTGCTAACCAAGTTACCAACGGCTGCTGCCAGTGGCGCTTTTTGTCGTGTCTTACCGGGTTGGACTCAAGACGATAGTTACCGGATAAAGGCGCAGCGGTCGGGCTGAACGGGGTTCGTGCGCACAGCCCGGCTTGGAGCGAACGACCTACACCGAACTGAGATACCAACCCAGCGTGAGCTATGAAAGCGCCACGCTTCCCGAAAGAAGGGAGAAAGGCGGAGAGAGGTATCCGGTAGCGGCAGGGTCGGAACAGGAGAGCGCACGGGGAGCTTCCACCACGGTACCTCTTTAAGTCCTGTCGGGTTTCGCCACCTACAAGCGAGCGTCGATTTTGTGATGCTCGTCAGGGGAGCGAACCTATGGGAAGCGCCTTCCGGCGCGACACTTTCTGGGGTCTTCGTTTTTTGCTCACATGTTCTTTCCGGTATCCCCTGATTGTGTGG
-+
-;;?22%%8@OM@??@><=:EEE9=CB5:1-9)1$#&'%1%'0&(,-&(?==?9)*<:>/'6.''+%&65/+,(,.*/<<85).7@889%(%%$'#('(0+($*''%(&'$2459@-%9$),3'*&%'%*.33/,/&,$($,.$&'().&3*+,2(%&(%9:?=<8=:25:C?'C<;/-/./9-<3<;87;87';454CFAI@++1<A@DE??@;793E?B?1//045504(:E;6;;<05-798BF=AABA>448$/;93+;<912=,0B??@-43:82,DFE;1>),--,//8B05?DOC-&4(+,8454@??@15##$/1/04++0/@?EE>39&(9((1=BD@=?>=/4//$/1==BBAA@FD>8.*,-5<FBA-4<<:DIBI<@97&1+*(,57+04(3639460/$,%%9=44D12*-,696/&2236;*,.<5-8.843BD*>7=*,>2,7&&.&&$&'%'$)''$$%223')+(79<63:A7<HNL>:947*&'&$)$&$)&&2:1+<A=CHQE@:975.,062)5-:873$-2+*+41,+/((%%&&(&&&*+*86;>523.2'&&(-)++-8C=@DC>CLCQFFECA0@3<@EDCA9FEE=<<6<:))+))8;;@B9>;?5>
-@3903ad0d-208b-48d9-b2eb-010c5552927d
-GTTGCTTTGATTAGTTGTATTCTTCTATATCACGCGCGCATGTCTGGCGACTGGAGATGTATAAGAACAGGACGAGCATCACAAAATTGAAATACTCAAATCAGTGGTGGCAGAAACCCGACAGGACTATAAAGATACCAGACGTTTCCCCTGAGTGTATCTTCTCCCTCGTGCGCTCTCCTGTTCCCGCCTTTCGGTTTACCGGTGTCATTCCGCGCAACATGGCCGCGTTTATCTCATTTCCACGCGCCTGGCACTCGGATGAGCAGTTCGCTCCAAGCTGGACTGTATGCGACCCCCCGTTAGTCCGACTACCACGCCAATTTCGGCAACTATCTTCTTGATTCAATCCGAAAAGAGCACGACAACACGCCATTGGCGGTAGCCACTGGTAACTAGATTCACGGAGTGAGATTGCAGAACTTACACAAGAGTTCTTGATAGCAGCCTGACTACGGCTAAACTGAAAAAACAAGTTTTGAGTACGCTCCGTGTAAGCCAATGAGTTACCTGGTTCAACGAGTTCCCCAACTCATTGAACCTTTAGCTCGCCTCCCAGGCGGTTTTTTCATCCCCAATTAGCCGGTAATCCGCGCCAAGAAAACGATTCAGAGATTACAAAACGATAAATGCATCGCACCAATCGTTCAAAAAGCAAAAAACGATCAAAGCTCGCTGACATACAAAAAATTTATATAATCAGGCTTCCGGAATTATCTATTAGCCCGTACAATAATTGGAAATCTGCCTGTTTTTAATACAGTGACAACTACGACCTACAGAGGTATGCGTATGAACGCTATTAATCGACGACTTACAAGTAAGGAGGTGCTAATGAAGAGAAATCGTATATGTTGGCGGTGCCGAAAAGACCTAAAAAATCATTCACAAAAGCCATGTTTGATGAGGTCTTGGTAGAGATAGTCCGCTTACAGTGCGGAATTCAACCTATCAGAAAAATAAAACAATGAACGGCCTCAGAAGGGTCATGGAATGGACAAAAAATGGAAAGCCAGCATACAGACTGGTTATGTAGTAGGAAGAGCATTTTCATACTACACGCTTTCAAAAACATCTGATGGGACCCAAAATCGAAGAGGAAATCAAAAGAACGATATAACAAATATCAAAAATCGTGTAAAAAACAAAAAGGCAAACAGTGGTCACACCACTGCTTTTTACTTTAACATCAATAGGGCTTTCTTTATCTACGGCCGAAAGACACATCATAACAAAACCCCTATTCTGCAAAGCATTTCTAAAGATATCTTTTATTTACAACACAGTGTGTGTTTCATTTGGCTATCTTCTGATAGGTTGAATTCCGCACTGTAAGCGGACTATCTCTACAAGACCTCATAAACATGGCTTTTGTGAATGATTTTTAGGGTCTTTTCAGCACCACCAACTTCTTTCATTAGCACCTCCTTACTTGTGTCGTCATTACACCTACCTCAGCAGAGTCAGCTATAAAGCCTCTGAGTGCTGATATGACCTCTCTCTCCGAGCCCACGAGACACGCGCGCGTAGTAGAGCAATATGGCAAAAAAAAAAAAATCGGTGTGCTTCCGTTCCGGTTACGTATTGCTCACGCTGACGTGTGTTCGTCGGCAGCGTTTGAGATTGGTAACATAAGAGACAGGCTTCGAGGATTTCGTTGGAGTTCAGGGTAAAACCGCGTGGGGTACCTTCGCCAGGTTACGGCCCACGAACTGTTCGCGGACTTCATCGCCCGGGTAAGCCGAACCGATTTCGTGCTTGATACGTTCTGCGGTGGCTTCACCGATCAGGGAGGCGCCGTATTACGACGCATGGTTGATGACGCTTTGTCGAAGCGATCGCCACCAAGCCGCGCGCGGAGAGGAGTAAACCACGCCGTTCAAGGAGATAACAGCAACTTCAGTGGTACCTACCGATATCAACCACCATAGAACCGGTCGCTTCCAGAAACCAGAAGCAGGCCAGCACCAATTGCGGCAGCCATCGGTTCTTCAATCAGGAAGACTTCACCCGGGCACCAGCGCCTGCGCCAGGATTCACGAATTGCGCGGCGTTCAACCTGGGTCGCGCCAACCGGTGTTGCACAAAACCAGAACGCGCGGGCTTGGACGCATAAAGCTGTTGCTGTGCACTTGTTTGATGAAGTGCTGGGCATTTTCAGTCACGAAGAAGTCGGCGATAACGCCGTCATTGGGCGAATGGCGGCAATATTGCCCGGCGTACGGCCAGCATCTGCTTCGCGTCATGACCTACTGCAGCTACGCTTTCGGTGAACCGGCACGATCCTGACGAATGGCCACCTGGAAGGCTCATTCAATGCGATGCCTTGTCCTTTTGCGCTGATGGACATTCGCAGTACCCAGGTCAATGGACAAGTCATTGGAAAAACATACCACAGAAATTTTTCAACATACTAAGGGATAATCCTGAAAGCTGGGGCGGAAAGAAAATCCGCTTACTTTACCAATACACGCAGCAGCAGAGGCGCAAAAATCATCACTACGGTGAAAATTAGATTGCGAGAGTTCGTTTCCCTTTGTTACAATCTGCCTGAGTCCAGAAAGGCTTAATGCATCAACAGCATTCCTCGCCTGTTTGCAACCGCGTGAGTCATTCATCTGCATATGTGTGCAACAATCTGGCGAGCAGACAAGCACACTCCCGTGAGGTCGCAGCGCGCGTTATTCTACGTGAAAACAGATTAAACGGCAGGTTAAACCGAGTATCTTTGGCAGATATTTTTTCACGTTGGTATCAAACGGCTGTGAGGACGCGAAAAAAATCCCCTTGCCCGCACAGCAACACCGCGCTGGATCAGGTCTACCCTCGCTTTAAAGACGCACACCAGTGGCGTAAACTTGGGTGCTGGTCCCGGAGCAGGCTTCCACCAGGCTTTGAGAACCAGCAGCTGGTTCTCCGTTCTTCTCAATGTTTCTGACCAGCGGATGGAGCTTGAGTAACTCAACATTAAGTTGCTTTGATCAACTGGTGCTTACCAGCGTCAAACCAGCCTGGTTGACGGCTACCCCATCACCCCTAAAGCATTCACTAAACGAATAACGGGTTGTAAACGCGACTGATATGTTGACCTACATCGGCCTCTGCAAATTCAATAATTATGCGTTTCGTTGTGATTTTCACATTGCATTAACGTATCGCGCAGCCAACGCTGAAAAACGCAGGCGAATCAGCGACTCAACGGTAACCTGAATCGCCAGATTTTCCCTCCAGCCAGTAACGCAATAGTGAATGAATGGCTGATTTCGAACGGTCATACCTCTTCCCGATAAAATAAACTACCGAGACCATTCGGCATGCTCTCCGCCGAGCTAACCTACTTCATTACCATGAAGATGCGGCACATAGGAGTTCGCGATGTTGAACCTGACCTTCGCGAGTAACCGCCGGTTTTTGATAAAGGCGCGGGCCGCCGCGACTGAGCATTTGCTCTCGATAAGCGTACCAGCGAACGCTACACGTCCTTTTTCAGGCAACGAGTCATCGTAAATAGCCTTCATTGCCGCCCTGCAACGCATTACGCCGTGGCAGACTCTGCATGTTCCATTACCGCAACCGGTATCTGACCGCCGCAGGCGCAGATTTTTGTGTGGATCATATCGTCGCGATCGAGCATTTTATTGTTCGGCAAGGTATCGACGGCTTTGATTAACTGACCGGCGATGCTCTCTCTTTTAACGTCCGGTGCGGTAACAGCGCAGCAAAATCACTGCGGTGGTAACGCGCCAGCAGTGCGCCAGGAGAGTAGCGCATCATAATGTCGGTGGCAGATTCGTCAAGTGAAGAACTGTTGCTTCCCAGCCTGGCTATTTTTAGTATCAGCTCAACATATTGAAATCCGGCAGACGAAAGATCATCATCACGATCCCGTGGGTACCTACTTTCTCCTGATCTTCCAGTAACGTTGCTAACTGATTATCGAAAGAGTCGGTTTATTGAGGCCGGTTTCACACCCTGGGCGGCATAAAACGGATCAGCGTATCAAGACTACAGCCGTGTTGTTCGCGTGCGTTCTGAGCTTCACGAAGCAGCGTATCTAGCGCACTGCTGTGCTGGGCGGCCATTCGCATAGATGGTTCCCAACACGTGAAACCCGCTCACCGTTTAAGATACGATAGCGGTTTCCAGCGTTCTTGCCCGGCAAGTTTGCCGTTAACCAGCGTACCGCCAGAACATAACAATGATAAAGCCAATCGCCCCCGTGAGCGGCGCGGTAGTCATTAAAGAATGGAAATAGTTGCCGCTCGGATCTGATAAAATAGACGCAGCGACATCCCCGGATGCTTTATCAACGGAACACTCAGTTCGCGAAACAGATCGCTGGAGCCAACCGGACGATAACTACCATTTCTGGCCGGGGTATAAACCTGTTTATCACCATGGAGCAGGTCTACACAGATGATATCTGCCGACATCGATATTCGGTAATTTGTGGCCTTAATGTGCTGAAGTCATTCGGCTTCGGTGGGTATCAATCGCCGTGCGCCACCACCTGAACGCGATGGCTAAACTTATACTGAATTGCGTTGGCAAAGCTTAGCGAATAGCCCAGCAAAGTCACAAAAATTGTTCGCCCGGTGAGCAGCGTAACAAAGGCCGAGAACTTCGTCGTTAATCTCATCGCTTGTGTTAACTCCGGTAGCAGTGAGGAAGCGGGCATACTAACTAAATCAGTTTATCTCGCAATTTATTGCGCTTCATCAACTTTGCTTTTCCATTGTAGTATAGTCTTCAGAAATTGTTTTCAATCCATCATGTACATGAGGACCACTTATATACAGGCGTTACTTTTAGAACAGCAGGTTGGCAAAACTCTCGCATCGGTACAGACACTTGACAGAGAGTCCGCTGCCGGAGCGATGTCACGGTTGATGTTCACTGGTCAGGCCTGGACTATAAAGATGCGCTGGCGATTACCGGTAAGGAAAATCGTCGTAATTTTCCGGTAAGTTCTGGGATCGATTTTGCAGGCTTTGTACGCACACCAGCGAAGATCCGCGTTTTCATGCCGGTCAGGAGGTGTTACTCACTGGCTGGGGCGTTGGTGAAAACCACTGGGTGGGCTGGCGGAGCAGGCGCGAGTGAAAATGACTGGCTGGTTGCACCATGCCGCAAAGTGGACGTAAAGCAATGATTATCGGTACTGCCGGTTTACCGCCATGCTGTGTGTGATGGCGCTGGAAGATGCCGGTGTTCGCCCGCAGGACAGGAGATTGTCGTGACGGGTGCCAGTGGTGAAAAATTGGCGGTACGCGTGGCGCTGCTGCATAAGTTGGGTTATCAGGTCGTTGCGTTCCGGAAATTCGCATGCCGAATATCTGAAAGTTTAGGTGCCGGTGTCGTCTCCCTCGTGATGGGGTTTGCCGAATCCGTCCTCTGGAGAAAAACAAGTCTGGCTGGGGCAATTGACACTGTTGGCGACAAAGTGCTGGCAAAAGTGCTGGCGCAAATGAATTACGGCGGCTGCGTGGCGGCCTGTGGTCTGGCGGGTGGTTTACTCTGCCAACCACGGTCATGCCATTTATTCTGCGTAATGTCCGTTTGCAAGGGTGGATTCAGTAGCTGACGCCACCAGGGCGCGCGCACAAACCACAGCGGCGGCGATGCCGATTGCCGGAATCATTCCAACACCCGGGCGGCAAAGAAGAATATCTCTGTCAGAGGCACCGAACTTTGCCGAGGCCATCATTAATAACCAGATCCAGGGTCGCACGCTGTTGAAGGTTAACTAACCGTGACCCCAGCAAGGAATAATAGCAAGAGAACTCATTTTGACATCATTATTCAATCGGTTAACGGGAAAAGCGGTTGGCGGGACAACTCGTCGAACACCTTGGTCAGGAAGTTGTACAACATCATCCAAACTGGAAAGTCATGATTTCGACTGACCACAAATTGGTACGCATTGATACTCCTCTAAACAGCCATTATTGATATGCCTCCGTCGCCTGTTAGGTTTATGGTGCTTTGCCTGAGCGACACTACGCCAACCTGTTACTGATTTCTGGTCCATGGGGTGGATAATCTGATTTTATTTGACTACAAATTAACCACTCCGAACTATTTAATGCTGAGAATTGTCAGTGGTTGATTTTGCGTGCTTTAGCATTCACATCTATCAGACGATGCAGTGAAAATTGGGTAATCCCCAGCAACCACGCTGCGTAGCTGTCGTCTATCTTTGTCGCGATCACAAAAACCCTACATTATTTGTGGTCTGTGAAGATTATCACCATTGCAGCCCCTCATCTTCGCAGGGCTGGCTTTCAGCTTTTTCACCTTACGTTATAAAGTTCCGTCGATGATGGCGCTAATTTCGTGGTGTGCAGCTTGTTGCAAAATACACGGTGTTGAAGGTTATTTACGTAGTAGCTGTTGATTATCTTCCCTGATAAGACCAGTATTTAGCTGCCAATTGCTACGAAATCGTTATAATGTGCGACCTCGTCCTCCTGACGCAGTTTTGCGCTGCGGAAAAGGTGACATTGGCGCAACAGAAGGTATATTTGTTTTTTCGGAGGATAGCAGCAGATCGCTGCACAATGTCCATCAAGTCTAACATTGACCTCTGGGGCAAAATAGACCGGCGTCCCGGCCTGCTGGAATTTATAGCCATGCATACAGCTGTCGGGGCATACGCTTTACAGACGGCGGTGAAACGCCTGTCACAATCACACTAAACAAAGAGTACGGAACCCACTCATGGATATTCGTAAGATTAAAAAACTGATCGAGCTGGTTGAGAAGAATCAGGCATCTCGAACTGGAAATCTCCGAAGGCGAAGGTCGAGTACGCATCAGCCGTGCAGCTCCTGCCACAGAGTTTCCTAATGATGCAACAAGCTTACGCTGCACCAATGATTAAAGCAGCCAGCTCAATCTAACGCAGCCGCTCAGCGGCAGCCGTTCCTTCCAGCAGGCTTCCAGCAGCAGCCGGAAATCGATGGTCACATCGTACGCTCCCCGATGGTTGGTACTCTACCACCGCACCCCAAAGCCCGGACTGTACCAAAAGCGTTCATCGAAGTGGGTCAGAAAGAAGTCAACGTGGGCGATACCCTGTGCATCGTTGAAGCCATGAAAATGATGAACCAGATCGAAGCGGACAAAATCCAGGCAGTGAAAGCAATTCTGGTCGAAAGCGGACAACCGGTAAATTTGACGAGCCGCTGGTCGTCATCGAGTAACAGGCGAACATGCTGGATAAAATTGTTATTGCCAACCGCGCTTGAGATTGCATTGCGTATTCTTCGGCCTATCGTAAAGAACTGGGCATCAAGACTGTCGCTGGCTGCACTCCAGCGGATCGCGATCTAAAACACGTATTACTGGCAGATGAAACGGTCTGTATTGGCCCTGCTCCGTCAGTAAAAGTTATCTGAACATCCCGGCAATCATAAGCGCCGCTGAAATCCTCTGCCGGCGCAGTAGCAATCCGCATCCGGGTTACGGCTTCCTCTCCGAGAACGCCAACTTTGCCAGGCAGGTTACAGACGCTCGGCTTTATCTTCATTGGCCCGAAAGCAGACACTATTCGCCTGATGGGTGACAAAGTGATGTCGGCAATCGCGGCGATGAAAAAGCGAACGTTCCTTGCCGTACCAGGTTCTGACGGCCCGCTGGGCGACGATGGATAAAAACCGTTGCCATTGCTAAACGCATAGGTTATCCGGTGATTATCAAAGCCTCCGGCGGCGGCGGCGGTCGTGGTATGCGTGTAGTGCGCGGCGACGCTGAGCAGCGCAATCCATCTCCATGACCCGTGCGGAAGCGAAGGCCGCATTCAGCCAACGATGCCAGTTTACATGGAGAAATGGAAAATCCTCGCCGCATCGAGATTCAGGTACTGGCAAGTCAGGGCAACATCTATCTGGCGGAACGTGACTGCTCTATGCAGCGTCGTCACCAGAAAGTGGTCGAAGAAGCACCAGCACCGGAATTACACCCGGAACTGCGTCTTCATCCGCGGCGAACGTTGTGCTAAAGCGTGTGTTGATGTCAGCTATCGCGGTGCAGGTACTTTCGAGTTTGTTCGAAAACGGCGAGTTCTATTTCATCAGGAAATGAACACCCGTATTCAGGTAGAACACCCGGTTACAGAAATGATCCACCGGCATTGACCTGATCAAAGAACAGCTGCGTATCGCTGCCGGTCAACCGCGTCGATCAAGCCGCAAGAAGAAGTTCACGTTCGCGGCCATGCGGTGGAATGTCGTATCAGCGCCGAAGATCCGAACACCTTCCTGCCAAGCCCGAGCAAAATCACCCGTTTCCACGCACCTGGCGGTTTTGGAGTGCGTTGGGGTCTCATATCTACGCGGAGCTACACCCGTACCGCCGTACTATACAAACTCAATGATCGGTAAGCTGATTTGCTACGGTGAAAACCGTGACGTGGCGAGTGCTCGCATGAAGAATGCGCTGCAGAATGATCATCGACGGTATCAAAACCAACGTTGATCTGCAGATCCGCATCATGAATGACGAAGAACTTCCAGCATGGTGGCACTAACATCCACTATCTGGAGAAAAGAAACTCGGTCTTCAGGAAAATAAGACTACGAAAGCGTCAAAAGGCCGGATTTTCCGGCCTTTATTACAGGGATCTGGCAACCCCCGCAAGGTACAATCCTCTTTTCTTCACCCATCAGGGACAAAAAATGGACACTCGTTTTGTTCAGGCCCATACAAGAAGGCGCGCTGGGCGCTGGGGCTGACCCTTTTTGTGTTGCTTCTTGGTTTTGGTTAGTAGCCGCTTACTTACCTGGCGGTGCCCCCGGTTTTACCGGCTTTCCGCGCTGAGTTTGAGATGGCCCGCCTGCATCCTGACGCCGCTACTGTTTATTGGACTGTGCTGGGCGATGGTGGGAATTTATCTATCGCGATATCCCACTGGAGGATGATGCAGCTTGAAGTAATTCTACCGCAGGTCGCCTATCTGGTGGTGGTGTTCGGTATCTCTGTTTTATGCACGATGCGTAAACGGAGCACCGGCACCGCTGCTTAATAATTATTTCCTCGGCAGCCGCTCTGTGGGCGGTATTGTGCTGGCGATGACGCTCACCGCGACCTATATCAGTGCCAGTTCTGGTTTATCGGCGGGCCGGGAGCTGCTTATAAATACGGCCTGGGCTGGGTATTGCTGGCGATGATTCGGCTTCTGCAGTCTGGCTTTCACTCGGTATTCTCGGCAAAGAAGTTTGCGATTCTTGCGCGCCGCTACAATGCAGTGACATGAACGATATGCTGTTTGCCCGCTACCAGAGTCGTCTTCTGGTGTGGCTGGCGGGATTGAGTTTGCTGGTTGCGTTCGTTTGGTTGCGATGACCGTGCAGTTTATCGGCGGTGCGCGCCTGCTGGAAATCGCGGCGGGTATTCCTTATGAAACCGGGCTGCTGATTTTGGTATCGGCATTGCGTTATATACCGCCTTTGGTGGCTTTTTTCGCGCCAGCGTGCTGAACGACACCATGCAAGGGCTTGTGATGCTGATTGGCACCGTTGTTGCTGCTTATTGGCGTGGTACATGCCGCTGGCGGCTTAAGCAACGCAGTACAGACCTTGCAAACCACCGAATACCACTGCAACTGGTTACGCCACAGGCGCTGAAAGGCGATATTCTGTCGCCTGCCTTTATGACGTGATTCTGGGTACTGGTGTGCTTTGGCGTGATTGGCCTGCCGCATACTGCGGTGCGCTGTATCTCTTATAAAGACAACAAAGCAGTACACCGGGGATATCATCGGTACGATTAGCAGTCATAATCCTGATGTTCGGTATGCACCTGGCCGGAGCGGTGGGTGGTGGTGATCCCCGATCTCACCGTACCGGATCTGGTGATCCCGACGTTTAATGGTAAAAGTGCTGCCACCTTTTGCTGCCGGGATCTTTTTCTGGCTGCACCTATATGGCTGCGATCATGTCGATAATTAACCCCAACTGCTGCAAAGTTCCGCTACGATCATTAAAGATCTCTATCTCGTCCGGATCAAATGCAAAACAGAGACGCGTCTGAAGCGGATGTCGGCGGTAATTACGTTGGTTCTCGGCGCGTTGCTGCTTGCCGCCTGGAAGCCGCCGAAATGATCATCTGGCTGATTGCTAGCCTTCGGTGGGCTGGAAACCGTTTTCCTGGCTGGCCGCTGGTGCTGGGTCTTCCACTGGGAACGCGCAACGCCCAAAGCGCGCTAAGTGCGATGATCCGTTGGCAGCGTGCTGTATGCCGTACTCGCGACGCTGAATATTTCAATTACCTGGGCTTCCACCTATTATTGCCCTCGTTACTACTAAGTTTTCGGCTTTCCTGGTCCACGGAAACCGTTTCGGTACATCCGTCCCGCAAACTACCGTTTTGACTACTGATAAATAAGAAATTTTGCCATTGCCTTGGATCAACTGAAACTGAACACCGGCGCAGACGCGGAAAGTCTTAGCGATGCGCTGGTGGAAGCGGTGCCGTTTCTATCACTTTTTCCGGGATACCCACGATACGCCAGTATTTGGGCCGCTGCCGGGCGAAACGCGCCTGTGGGGCGACACCGATGTGATTGGTCTGTTCGACGCTGGAAACCGATATGAACGACGTGGTGGCGATTCTGGAAAACCATCGCTGCTCGGCGCAGGCTTCGCCTCGAACAACTAGAAGATAAAGACTGGGAAGCGCGAATGGATGGATAATTTCCACCGATGCGCTTTGGTGAACGACTGTGGATCTGCCCTAGCTGGCGTGATGTGCCGGACGAAAACGCCGTCAACGTGATGTTAGATCCAGGGCTGGCGGCGTTTTCAGTACAATTACCCTGATCCAACCACCTCTGTGCCTGCAATGGCTCGACCAGCCTCGATTTAACCGGTAAAACAGTCATCGACTTGGCTGTGGTTCCGGCATTCTGGCGATCGCAGCGCTGAAACTGGGTGCAACAAAAGCCATTGGTATTGATATCGATCACCAGGCGATTCAGGCCAGCCGCGACAGCACCAGACAATGGCGTTTTCTGACCGTCTGGAACTCTACTTACCGAAAGATCAGCCAGAAGAAGTAGCCGACGTGGTGGTCGCTAACATCCTTACAGGCCCATTACGTGAACTGCTTCCTGTCTCTTTTATACACATCTGACGCTGCCGACGAACAC
-+
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
-@eaa3d694-6e4e-41a6-9ed3-67bab03aa12b
-CGGTAGCCCACTTCGTTCGGTTACGTATTGCTGCGCGCGCGCGCTCTCTGTCGTCAGCAGCGTCAGATGTATAAGAGACAGGTGTCAGCTCACTCCAAAAGCAGTAATACGGTTATCCACAGAATCAGGATAAAGTCGGAAAGAACATGTGAGCAAAAGCAAAGCACCGGAGGAAGCCAGCGCCGCAGGCGTTTTCCATAGGCTCCGCCCCCGTGACGAGCATCCCACACAAAAATCGACGCTCAAGCCAGAGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGTGTTTCCCCCTGGAAGCTCCCTCTCGTGCGCTCTGTTCCGATACCGCTTACCGGATACCTGTCCGCCTTGCTTTCTCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCGGTTCGGTGTGGGTCGTTCATCAAGCTGGGCTGTATTGCACGAACCCCGTTCAGCCCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGAACCAACCCGGTAAGACACGATGAAGCGCCACTGGCAGCCATTGGTAAAAGTCGATGTGCGAGAGGTTCAAGAGAGTACTTGAAGTGATAGCCTGACTACAGCTACACTGAAAGGACAGTTTTGGTGACTCGTCTCGCACAAGACGGTTACCTGGTTAAGCAGTTCCCCCAACTGAGAAGCAACCTTCGATCAGACCACCTCCCCAGGGTGGTTTGATCGAAAGGTTAAGTCAGTTGAGACAACCAACGCGCTGATAGGAGTCTAAACTGTTTTTCAGTGGCAGCCTAGTCGAGCAATACTCTCTTGAACCTCGACTTTTTTCCAATGGCTGCCGGCGGCATCTTTAAGGTGTCTTCGGGACGAACTCAGGCGATGAGTTACCGGATAGCGGCGGTCGGCGAACAGGGTTCATTACCTGGCCAGCAGAACCAGGCTGACGCCGAACCGGGCCCAACGTGAGAAACTAAAGCGCCGCACGCTTCCCGAAGGAGGCGGACAATATCCGGCGAAACGGCGGGTCATGTTGAAGAGCTTGCGAAGCTCCGGGGAAGCACCTGATACATAACCGCACCTGGTCTACGTCGGGTTTCTCACCTCTCTGGCGAGCGTCGATACAGCGATGCTGCTCGAGGGAACGCGTGAAACGTGGAAAAGCACTTCCTCTGCAACAACCTTTTCAGGGCCTCTTTTTTTGCTCCACATGTTTTCAGTGTTATCCTGATTCTGTGGATAACCATATATCCATTGCGTGAGCAGGGCTACACTGCCACAGCCGACGACCGAGCGCGGCTTGAGTGTAGTGAAGCGAGGAACTGAAGAGCGCCGGAAGCTGCATTTCTCACTTACGGCGTATCTGTGCAGCATTTCCGCACCTCATATGTCGCTGTTCTCTCACCATCTGCTCTGGCGCCGCACAATTAAGCTAGTATACACTCCGCTATCGCTACGTGACTGGAGTCATGGCTGCGCCCCGACACCACTAAAAACCTGACGCGCCCTGACGGGCTTGTCTGCTGGCAGAAGCGCCACGGGGAAAGCCGTGACCGCACTTTCGTCAGCTTCGTTATGTTCCTGTTTCATTTTCCCGGCCTCAAAGCGAATCCGGATTGCTGTTCTGAGTTCTTAGGTTCGTGCAGTCGTTCGCACGCATAGCCGCTGTTCGTCGGCATCCAGGAGCATCATCCAGTTTCAAGCAGTGTCAGGCTCCAGCGATGAAATCTTGCTGCGCCATATTTAGCGCTGTGATTTGTTGTTTGGTGTTCTACCTTCCGTTGTTCACAACACCTTCTCCGTGTCAGTGGTTCCGGGTGTATTAAGAAAGGACTGACCCTGAGCAGCGCTGTGCGTTGTGAGTGGGCGGAGGTGTAGAGACGTTGCAGCGGGCGTGACCTTTGGTGAGTATTACAGTGTTGTGGTGATTATTGCCCTTGCCACA
-+
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
-@ff14be5f-894d-4a57-86e5-b9cffbfcbc82
-CGGTGTACTTCGTTCAGTTACGTATTGCTGCGCGCACTCTCTGGTCTCGTGGGCTCGGAGATGTGCTATAAGAGACAGCTCCCTCACGTGCGCTCTCCTGTTCCAGCCCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTCACCGCAGCTCACGCTGTGGTATCTCGGTTCGGTGTGGGTCATTCGCTCAAGCTACATTTGCGCTGTGCACGAACCCCGTTCAGTGACACTTTCGCCTTATCCGGTAACTATCGTCGCGGTCAACCCGGTGAGATACGACAAAGCGCCACTGGCGGCGGCCATTGGTAAAAGTCGATGTGCGAGAGGTTCAAGAAGTACTTGGAGTGATGGCCTGGCCTTCTGGCTACACTGAAAGGGCAGTTTGGTGACTCGTCTCGCACAAGACAGTTACCTGGTTAAGCAGTTTAACTGAAGCAACACTTCGATCGACCACTCCCAGGTGGTTTGATCGGGTGGGACTGTAACCAGGTAATATCTTCGTATTTCAACAGCCTGATCGAGCCATCACTCGAAGCCTCTTATCACTAATGGCTATCTTTATAGTCA
-+
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
-@aa871259-cd4f-4521-a047-29d019a3bbb6
-GTTCGTTCAGGATTACGTATTGCTGCGCGCGCACTCTTGTCGTCGGCAGCGTCAGATGTGTATAAGAGACAGCACAGGAGGTGGTTTGATCGAAGGTTCAAGTCAGCTGAAGGCTTCTTAACGCCAGGTAACTGTCTTGTGCGAGACGAGTCCACCAAAACTGTCCCTTTCGAGTGTAGCTGTAGTCAGGCCATCACTTCAAGTACTCTCTTGAACCTCGCACATCGACTTTTACCAATGGCGCTGCTTGCTGCCAGTGGCGCTTTGTCGTGTCTTACCGGGTTGGACTCAAGACGATAGTTACCGGATAAGGCGCAGCCCGGTCAGGGCTTCCGAACAGGGGGTTCGTGCACCACAGCCCAGCTTGGGGCAGACGACCTACACCGAACCGAGATACCTACAGCGTGAGCTATGGAAAGCGCCACGCTTCCCGGGGAGAAAGGCGGACAGGTATCCGGTAAGCGGCAGGATCCCGGGAACAGGAGGCGCACGGGGGCTTCCAGGGGAAACCTGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTCTGGCTTGAGCGTCGATTTTTGTGATGCTGCTCGTCAGGGCCAGACCTATGGAAAAACGCCTGCGGCGCTGGCTTCCCCTCAGTTACTTTCTTTTTACTCACATGTTCTTTCCGACTTTATCCCTGATTCTGTGGATAACCGTATTACACCGCTTTTGGGTGAGCCTTATCACGCCGCAGTCGAACGACCGAGCGGCGAGTCAGTAGTGAGGAAGCGGAAGGCCGCCTTATGTGACGTCTCCTTACGCTCATTTGTTGCCAGTTCGGCATCCTGTCCTGAGCGATTATCTCTGTGCTATTTTCTACTTCAAAGCGTGTCTGGTTCTTTGTTCTGGGTTCTTCTGCGAGTTCGTGCAGCTTCTCGCATGGCAGCCTGTTCTGATCAGCATCGGTGCGTCAGTTTTTCGAGCAGCGTCAGGCTCTGACTTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCCCGTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACACCACGCTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTGACGGGCATTTCTGTCAGACAACACTGTCACTGCCAAGAAACTGCCGTGCCTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCCTTACATGCGCTATTACAATTGCCTGGTCAGGGCTTTGCCCCGACACCCATGTCAGGCCAGACCACGTGTTTTTGTGACAAAACGAGGGTGGAAGTAATACGCGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACGGCAGAAGAAGACCAGGAAATCAGAAAAAGGGCTGCTGAATACGCAAGACCGTTTCAGTTTTTACGGGCGGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCGAATTTACTGAAAGAGTTATGGAGACTGGGGGCGATTACAGAAAAACTCTTTATCGACGGCAAATGATGTCGGGGACAGGGAGTATGCGGGTGCTGATCGCTATTACGAATATCACCGTGCCCTGTTATCCAGACTTATGGCAGATTAAGCTTCCCGGAGGAAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCCGGGGGTAAAACATCTCTTTTGCAGTGTCTGCGTCAGAATCGCGTTCAGCGCGTTTCAACAGTGCGTCACAATTACAGCATTATGTTAAATTTTATAATTGTCTTTAGTCATTGCTATGATTTTGTAGGTGGAGTTGTTTCATATTTTTGATATAAATTCTTTTATCTCTGAAACAGTCATCGTCAGTATCAATGGTTTTGTTCTTCATTGATATGCCTATTCTAGAATCTTGATTCCTTATTACAACTAAGATTAAACTTGAACTTTTGCTTTCTTTTTCTTATTTGGGTAAGCGTAATCAGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTTTATTTTATTGAATAGATCGTCTATATATCTAAGCACCTCTTTCTTACACGCGTGAGCAATGGTTAGATCTTCTATTGCGCCATTCTTGTTTTCCTGGCATGATAAAGAAAGATATTTTTGTGCTTCCGTTAATGGCTATTTCATTATGCGAGCTTGAGTGAAATGTTAAGCTCATTTAATGTTGAAATTATCGATCTTTCCGTGTCGGAAAACGATTCGTCAGCATCGATGATTAAGAATATACTTTCTTTTCATTAAAAGAGACTCTATGCTTTTAAATGCTCTAAGGGTTTGTTTAGTTTTGTCTTTCCATTTATTTTTCAACATAAACATCATTAATTCCTTCTATTTCAAGTAGATTGCAAAGGAAATTGAAAATCATCATCACCCTCCAGCGAAAGCTGGCTTTTATAATCATTTATTTTCTCGGTTTCATTTATCTGCCTCCAATATTTCCAGCTGAAAAGAAAATCATCCATGTTAATTGCATTGCTGTGGGTTTGAGATTCCTTGTCTCTTCCCCAGTCTTATGTAAGATATATCTTTTCTTTTTTCATCTAATTCGTTTATCACTTTTATATTACATCATGGCTGTGTGTTGTTGTAAATATTTGATTATTATTATGGTTTTCTTACTTCTTAAAGCGTTGATCATATCTTTGATTACTGAGTAATGAATTCCATTTTTCTATCTCATCAGTAAGAATAATGCGTCTATCAGGTTAGTACATTTTTGCAAGACAGTATCTGCATATTACAAGCATTGATATTTATTTAATTCATAAGTCCTATATCTAAAAAATCTCTTTGTTTGATCTGTTGCTATTATTGCAATATCGTTAATCCTATCTGACTAACTTGCAGGTTGCCTATTATTTCGTCTTTCTTTTTTATTGTTAGTACTTTCAGTGTTTTATCTGTTTACTTCTTTGTTTATGTTCTAAATGTGGTTATTATCGCTGCGGTTTTGAATTCATATAGCTTACCTTTTTTAATTTGTTTATTCTCCAGTTTATTTCTTTGTTTTGTTATTTTTATGAAATACCAATCAATTCTTCTGGGGGGTTCTTTTTCCATTATATAAGCGCCATTAACTAATCATTAAACATTCCCTTTTCACACAGGCCGAGGGTTTGTCTCATAGTGGAGGGTGTTTGATAATATTCAAACTCTAACTATGGGGACTGCAGTTCCTTTGTGTGTTATCCTACATCGGTTGAGTATTTTTATGTGTTACTACATTGCTTCATCTCTTATTATTCGGATATTTGTTTGGATGTGTCCATGTTATAATAGCTATCCCAAAATGAGTTTTCTTTATTTAAAAGAGATCTTCATTTACAAGGCTTTTTACTTTTAACAGAGCTTCTTTGGGTTTTTACGTCATAAGAAGTAAAATATCGT
-+
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
-@4bb8872d-9dea-487a-adc6-19358de7c3f8
-GGTGGTTTGAGTCGAAGGTTAAGTCGGTTGAGAGAACTAGCAACCAGGTAACTGTCTTGTGCGAGACGAGTCACCAAAACTGTCCTTTCAGTGACCATCACTCGAAGCTATCTTCGAACTCGCGCGACACCAGTGGCTGCCAGTGGCTTGCTGTCGTCTTACCGGGTTGAACTGCTGATAGTTACCGGATAGGCG
-+
-)/9253-(+%(21+,''4%+*+',8'/8/($%%$$$"#&$&'(&+%--*('*25785==?44322742,7.6&'2356&/0.((4(50/$)&'$()3/4&&,*&&%$#%%%%%%%)%%%()),%((%$&'*%((&&$%&))#.-**$$$%%37:0+(()*&(1)*=21310%'*&&6547:740).-13(*%),,
-@0b0af326-f003-4b00-a324-fa095a6bd0ad
-GTTGTACTTCGTTCCGAGTTACGTATTGCTGCGCGCGCACTCTCTGGTCTCGTGGGCTCGGAGATGTATAAGAACCCAGCCCCTGGAACTCCGCTCGTGCGCTCTCTGTTTCCGACCCTGCCGCTTACCGGATGCGCCGTGCGCGCGCACCCTTCGGGAAGCATTGGCGCTTTCTCGCATAGCTCACGCTGTAGGTATCTCGGTTCGGTGTAGGTCGTTCGCTCCAGCTGGGCTGGCGCGAACCCCCGTTCAGCCAAACCGCTTGCGCCTTATCCGGTAACTATCGTCTTGAGTCCAGCCCGGTAAGACGACAAGCGCCACTGGCAGCAGCCATTGTAAAAGTCGATGTGCGAGAGGTTCAAGAGAGTACTTGAAGTGATGGCCTGACTTCTGGCTACTGAAGGACAGTTTTGGTGACTCGTCTCGCACAAGACAGTTGCCTGGTTGGCAGTTCCCCAACTGACTTAACCGTGTTGGGTGGTTTGATCGAAGGATCGGATAGTAATGTAACGAGACGAATCACTGTCCTTTCGATGTAAATGTAACAATGAAAGCGATTCTGGCGCCACCGAACCTACAGCTACGCGAAGGAAAAAAGCGATAAGCGCAATCTAAATCAATTAATGTCTTTATAGTCCTGTCGGGTTCGCCACCACTGATTTGAGCATTAATTTTTGTGATGCTCGTCAGAGGAGCGGAGCTGTGGAAAAACGCCCCGCTGGGCGGCCTTATGCTCCTGTCTTTGGTTTGCGCTCCCATGTAAGTTATCTCACTCTCTTACTTGTCACTTAGTCAGCTCCGTCCGCTCGCCGCAGATAAGTGACCGAGCGTAGCAGAGCGAACGATCGAGAAGCGGAAGAGAACCTGATTTCACATGGAGCACTGACGCTGTGATGACGAAACAACAGAAAACTGCGCTTAATATGGCGAACGTTTATCCGAAAGTGCTTTTGTTGGAAAAGCAATGAACTCGATCTGGAAATGTTGAGGCGGATCTTTGC
-+
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
-@32c060be-1a2a-4b3d-9f4b-69aba16789f8
-GGTTCAAAGTACTTGAAGTGATGGCCTGACTACAGCTACACTGAGGACAGTTTGGTGACTCGTCTCCGCACAGAAGACGATTTACCTGGTTAAGCAGTTCCC
-+
-.>GC;04))*(-0267:=C<<DA><.AH81501//)()688461&<D96;?@<=@?B987B?=?A,@9;4-3'%%&*+'%7;:6>?>34=E>?<97:?;,--
-@49b3c5fc-395b-43bd-92d8-5bc6cdee2622
-GTTGTACTTCGTTCAGTTACGTATTGCTGCGCGCGCTACTCTCTCTAACTCATCGGCAGCGTCAGATGTGTATAAGAGACAGGAATTAATGATGTTTATGTTGAAAAATAAATGGAAAGGCAAAAACGCGGCTCAAACCCTTAGAGCATTTAAAGCATAGAGTCTTTTAATGAAAAAGTATATTAATCATCGGTGCCGACGAATCGTTTTCTGACACGGAAAGATCGATAATTTCAACATTAAATGAGCTTAACATTTCATCACAAACTCGCATAATGGAAATAGCCATTAACGGAAGCACAAAAATATCTTTCTTTGTCGTAGCGGCGGAAGCAAGAATGGCGCAATAGAAGACAATCATTGCTCACGCGTGTAAGGAAAAGAGGTGTTTAGATATATAGACGATCCTATTCAATAAAATAAAAGAAACAAAGAATCTATTATTACATCCTTAGATCCTGATTACATACCCAAATAATGAAAAGAAAGCAAAAGTTCAAGTTCTGTAGTTGTAATAAGAGATGGGGTCCTAGAATAGGCATATCAATGAAGAACAAAACCATTGATACTGACGATGACTTCTTCAGTGAGATAAAGAATTTATAAAAATATGAAACAACTCCACCTACAAAATCATAGCGCAATGACTAAAGACAATTATAAGAAATTTAACATAATGCTGTAATTGTACGCACCGCTGAAACGCGCTGAACGCGATTCTGACGCAGTACCGCAAAGAGATGTTTTACGGGAAAACAGGAAGGATGCGTCAGGATCGTTTTCCAGCTCGCCTGCATATTCACCGTGGCGCGAATGGTGATCGCGGGAGCTTACGTTAATTTCGCACCGTCTGTTTTCGACAGTTTTCTCTCCGGGAAGCTAATCTTGCCATAAGTCTGGATAACAGGGCACGGTGATACCGTAATAGCGATCAACACCTCACCTCCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTCTGTAACGCCCCAGTCTCATAACTTCTTTCAGTACTGATCATCAGTCAGTGAGTTAACCTTTCTTACCATGCCGCCGTAAAAACCGGAAACAGTCTTGCCGCATTCAGCAGCCCGCTTTCTGATTTCTGGTCTTCTTCTGCCGTCGACGAACAGAGGCGACTGATAACCCGCCTGCGCCGTATTGCTTCACTTCGTTTTGTCTCAAAAACATGGCTCCGTATCTGACATGGGTGTCAGGAGCCAAAGCCCTGACCAGAACAGTGTAATAGCGTGTATGCGCGGTATAACAATTGCACATCCTGTCCTATCAGCAAGCTCGAATTACCGACAAAGGCACGGCAGTTTTTGGCAGTAACCGGTGTTGTCTGACAAAAATGCAATCAAAAGCCAAGCGGCAAGAATAACGGCATAAAAACAGTCGAAAAGTGGTACGCGATATAATCACACAACGCAGATGACGAACCAGAACGGAGAAAACGAAAAGACGAACAAGCAGCAGCAAGCCGTACTCAACATGGCGGGATTATACAAAAAGTCAGAGCCCTGACGCTGCTCCTTCGAAAAACTGGACGCGCCCGATGCTGACGAACAGGCTGCCATGTTGCGACAAGCTACGAACTCGCGGAAGAACTCAGAACAGCATCCAGACACGCTTTGAAGTAGAAAATAGCACAGAGATAACGCTCAGGACAGGATGCCGAACGGCCTAACGGACGGCAGGAAAATATCCACATAAAGGCGCTCTTCGCTTCCTCGCTCACTGACTCGCTACGCTCGGTCGTTCGACTGCGGCGAGCGGTGTCAGCTCCTCAAAGCGGTAATACGGTTATCCACAGAATCGGGGGATAAAGTCGGAAAGAACATGTGAGCAAAAGCAAAGCACCGGAGGAAAGCCAGCGCCGCGAGCGTTTTTCCATAGGCTCCGCCTGACGAAACATAAAGAATCGACGCTCAAACCAGAGGGGTGGCGAAACCCGACAGGACTATAAAGATACCGGGTGTTTCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTGCCGGATACCTGTCCGCCTTTACTCCCTTCAGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAGTTCGGTGTAGAATCACCCGCTCAAGCTGGGCTGTGCTGACCCGTTAAACCCGACCGCTGCGCCCATCGAAGGTAACTATCGTCGGAGTCAACCCGGTAAAGGTACGACAAAGCGCCAGCAGCCATTGGTAAAGTCGATGTGCGAGAGGTTCAGAGCGCGAAGTGATGGCCCACATTACAGCTACACTGAAAGGACGGTTTGGTGACTCGTCTCGCACAAGACAGTTACCTGGTTAAGCCACCAATACTCTTATACATCTCCGAGCCCACGAGACCAGAGAGCGCGCGCACCTTGTGCAG
-+
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
-@05e46322-a839-43d6-8639-65ffc087abf1
-GATATACTTCGTTCAAGTTACGTATTGCTGTGCGTCTCGTGGGCTCCGGAGATGTGTGCCGGGAACAGCCGCCGCCCACTCTCTGTCTAACACGCTTGCCCGTCGATAAAGAGTTTTTCTGTAACGCGCCCCCAGCCTCATAACGCTTTCCAGTACCGAATATCAAGTCCAGTGGGATAACTTTCTTACAGGAAGCTGCCGCCGTAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCTTTTTTCTGATTTCCTGGTCTTTGCTTCTGCCCGATGGAACGAACAGGGCGACTGATAGCCCGCCTGCGCGTATTACTTCCACTTACCAGTTTTGTCATAAAACATGGCTCGTATCTGACATGGGTGTCGGGGCAAAGCCCTGATCAGGGTAGTGTAATAGCGTGCATGTATGCGCGGTATAACAATGCACATCCTATTCCTGTCAAGCAGCTCGAATTACCGACAAAAGCACGGCAGTTTTTGGCAGTGACGGTGTTGTCTGACAGAAATGCCCGTCAAAGAGTCAGACAGCAGAATACCCGGCGGTAAAACAGTCGAAAAGTGTACTCGATATAATCACACAACGCAGATGACAGAAAGAACGGAGAAAACAGAAAGATGAACAAGCAGCAGCAAACCGTACTCAACATGGCGGGATTCGCAAAAAGCCAGAGCCTGAGGCTGCTCCGAAAAACTGGACGCACTTGATGCTGACGAACAAGGCCGCCATGTGTGTGGCTGCGAAAACTCATGAAGAACTTCAGAGCAAGCATACAGACACGCTTTGAAGCGGAAAATCGCATGGGATATAACGCACCCCGGACAGGATGCAGAACGTAGCGGAGCGTAAGGAGAAAATGCCACGTCAGACGCTCTTCACTTCCTCGCTCACTGACTCGCGCAGCTCGGTCGTTCGACTGCGGCGAGCGGTGTCCAGCTCACATAGGCGGTAATACGGTTATCCACAGAATCAGGGGATAACGCCGGAAGAACATGTGAGCAAAAGCCATAGAAGCACCGGAACAAACCAGCGCCGTGCCGTTTTCCATAGGCTCCGCCTGACGAGCATCACAAAAATCGACGCTCAAGTCGAGGTGGCGAAACCAAACCGGGACTATAAAGATACCAGGCGTTTCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCCCGCCTTTCTCCTTCGGGAAAGCGTGGCGCTTTCATAGCTCACGCTGTTGGTATCCAGTTCGGTGCTTGGTCGTTCGCTCCAAGCTGGGCTGTGTGCACGAACCCCGTTCAGCGCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTCCAACCCGGAAAGACACGACTTAACGCCACTGGCAGCAGCCATTGGTAACTGATTTAGAGGAGTTGAGGTCTTGAAGTTATGCACCTGATGAAGCTAAACTGAAGAACAAGTTTTGGCGACTGTGCTCCTCAAAGCCAGTTACCTCGGTTTCAGAGCGCCAACTCACCTTCGAAAAACTCCGCCACTCAAGGCGGTTTCATTCAACGTTGATTAATCTCCTTGCTAGCTGCGTCAGCAAAGCCTAACGACTTCAGCCTTCTTTGCCTGGTATTGGCAACAGCTCATGACTGGGAGCCTTCTGGCTACAAGTACTCATCTTTGTGAACTCATCACGCATACAGCAGGCTCTCAAAGCATCATTCTTGATCCTCCATACTTCTCGATGACTAGAGAGCAGAGATCTGTCGCTCACCTGATTCTCCCAGGAGGAGCTACAAGCCAAAGCTCTTTATTAGGGAATCGCTCTCTTACGTATTTAATATAGGGGCATAAGTCAGAATCCGCAGTGATAATAATGGCTATATCATACTCATCATTACACGCACCAGACACTGAACTTATAGCCAAATTAACATCGGACTCTCTTTTTCTTCATGCTTATAAGAAGAAACTCCACCACATCCATTATCAGCTTCGCACGTTACATTCTTTTTTAAAACGTCCACCGATAACATCAACACACCACATTCGGTTAAAGCGTTGGTGTAATTTTGATAATTTTCATTTATGGCTCTTGATAAATGTGATGGCTTAGCGGAAAACCAAAAAACATTATCAATAGATGCACAGGAAGGTATCTCTTGCATAAAGATTTAAGATCAACCCAATGAAGAGCTTTATTACCAGTCTCTTCAATTGCATGATATAAATTATACCTGTCTCTTATACACATCTCCAGGC
-+
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
-@f75b2c81-63ba-46f0-a125-648548ee3f8f
-GTTTATACTTCGTTCAATTACGTATTGCTGCCACTTGCTATATACGTGTCTTCGTCAGCAGCGTCAGATGTGTATAAGAGACAGCTCAAAGGCTATTATTAATACGGTTATCCACAGAATCAAGGATAACGCCGGAAAGAACATGTGAGCAAAAGCCAAAGCACCGGAACAAACCAGCGCCGTTGCCGTTTTTTTCCATAGGCTCCGCCCCTGGCGAGCATCACCAAAATCGACGCGCTCAAGTCGGAAATTGGCGAAACCGATAGGACTACTCTAAAGATACAAGCGTTTCCCCTGGAGGCTCCCTCGTGCGCTCTCCTGTTCAAGGCCCTTGCCCAGCACCCCAGATACCGCATCGCCTTTCTCGCTTCCCGGAAGCGTAGCTCTCATAGCTCACGCTGTTGGTATCTCCAGTTCGGTGTGGGTCGTTCGCTCCAAGCTGGGCGGTGTGCACGAACCCCGTTCAGCCCGACCGCTGCGCCTTGTCCGAAGTAACTATCGTCTTGGAGTCAACCCGGAAAGACACGACTTAACGCCACTGGCAGCATGCATTGGTAACTGATTTAGAGGAGTTGAGTCTTGAGTTATGCACCTGATAAGGCTAAACTGAAAGAACAAGTTTTTGGCGACTGTGCTCCTCAAGGCCAGTTACCTCCAGTTCAAAGGCGCCAGCTCTATGGACAGCTGAAGAGCCGCCCGCCAGAGGCGGTTTTCCAGGGTTCATGGGGATGGCGCTCTTTGAACCGGGCTGAAAAGCGCATCGCAAAACTGTTCTTTTCAGTTGCTTATCGGGTGCGCCCCTCGAGACTCAACTTCCTCCCCCAAATCAGTTACCAATGGCTGCTGCCAGTAACAAAATCGTATCTTTCGGTTAGTAGTTACCGGATAAGGCTTACGGCTGTCCTACGCTGGGCTGAAAATTCGTACAGCCAGCGGAGCGAACGACCTACGCCGGAACTGGTATGAGAGCGCCGCGTATTCGAGGAGAAGGCGGACATGAGTATCGATGAAGCCGGGATCAGATGAGAGAGCGCGCGCGAATTTCCAGGAAATTTGT
-+
-(%%($%%%%%'6G1;&&&=57;9:780(('$$()/0++,-)(('.*%$$+,40431(,)'1--7;;7@D:.,)'3443,(-/+3??@63/*1%%+'*$&'$$20068?C<))7'4815/&<)*+4FI>>:A;G:<02-.8:>0//3./9@LOC-5&988,/66-BEGGC>8;/2<A<C;7.)#$,34/79<466?9>+-)38=>1;2122&-+,('&-=5+<2(:36-5+8779,.5?AF<=<58(+'*$$)*--*.3/4,%#$&09;68,+5;0AD?***'&#&,68FD==DG>62*,#&5956&-+$%'02470;/591:/)()'(56%%+-+/''$*.-/+.)).*%'1$$)*<%#&56=;3:&'0,%(9-8:9B;;/%%&'1/>.959;7?EC@@DB/19;<?..7$=5@65;05?:3&(.('%(&66:@*;797;:66:--5644-&%--+.?DDD=H3*4'??;?A@A<=B?<?@A@E/&&1(&$&)%%.1.0-(44()/14/&@'(&=;&.$)/778-::8664((0%%(4-?7<4.1.(((868=.5>;;9>@==F48)AG;:=CA97C87'&&&)9-$$%&)42<@A<432%,0139=<A4A67(.:>>28<BA?68854>A:1:AG8?/:-.)0:6.8=1(&-.'/'(543()&&84%%%%%:/5&$&-1/,$*+/024*(+4/()+4442)(*50?098:80%0$'&&.4-//%*-1,7.,&&&(&&(&&&))6'(,*-,*(%%%%#'&%'$+,-(&$4*24-,--0*%)(+$#&*0.7%+0:53%$$$$*)$$21998&''(*+.1+-(&%011,+$2%'%-.()206:<;88282+1'&&.$%'&%%%'%/0..-)$$--$'($&)0,%.&(-+,-'($$$&,'($&%$#%$%%$#$#&%#$%&'+,.*/)-&%#%,/.&,)-')00--96.+%#(:4=8*+*))*%'%$)2&%#)::;0,,'###'%($*'+$&%&+2,5-(&%'%'%&$.*$)$*'$%($'')$%#%$()%&'&%&%)%$$&'$$#%(*/1$%%$$$#&*#$
-@e8221e53-73b5-492a-a94b-1304576f10b7
-GATGTGCTTCGTTCAGTTACGTATTGCGCTAGAGGCTCACTCTCTGTCCTCGTCGGCAGCGTCAGATGTGTAATATAAGAGACAGAAAAATTCTCTTCTTTTCAAGATGCTTTGGTTTGGGCAGAAAGCTAATCCTAGCAAAACGATAATAAGATCTCAGACGGTGTGGGGTTTATTGAAAAATGAAAAGAGTGGATTCACTCAACAAAACAACGATGCATTTTTTGGACAACACCACTGTCTATATACGTACTCATATGTTTCACAGTGTCGTATATTTGAGTCTATGTTACGTACGTTACAGGAGCCTATTTTGACTGGTTACAGGCATTCTTGCAGCAGCTTACAGAAACCCTAGCTGTAATCCAAAGTGACTACCAGGGCTAGACGAACTTTATCCCCCACAAAACCCGCTTTTTAAACGGATCTTCTTGAGATCATTCATGGAGAATCGTAATCTCTTAGCATACAAACGAAAAAAACCGCCCAGCAAGGCAGTTTTTCGAAAGTTCTCCAAAGGCAGCAACTCTTTGAACCAGGGTAACTATTGGAGGAGCACAGTCACCAAAACTTGTCCTTTCAGTTTAGCCTTAACCGGCGCATAGCTTCCAAGACTAACTCCTCTAAATCAGTTACCAGTGGCTGCTGCCAGTGGCGTTTTGTCGTATCTTTGGGGTTGGACTCAAGTCGATAGTTACCAGCGGATAAGACGCAGCGGTCAGACTGAACAGGGGTTCGTGCATACAGTCCGAAAAAGCAGGAGCGAACTGCCTACCGGAACTAGCGAGTGTCAGGCGTGGAGATTAGATAAACGGCCATAACAGCGGAATGACACCGGTAAACCGAAGGCGGGAACAGGAGAGCGCACGAGGGAGCTACCAGGGGAAACGCCTGGGATCTTTATAGTCCTGTCGGGTTTCGCCACCACTGATTAGGCAATCAGATTTCGTGATGCTTGTCAGAGGCAGACCTATGGAAAACGGCAACGCCGCATCCTTTCCTTCCTTTGCAGTTATTCCGCTTAGTCTTTATCCAGCCATTCGTAAGTAGCAACGCCTGCAGTCACGCTTAGGAGCACAGCGACCCGGGTGGGACTGCGGCGAAACACGAAATGGCGCTGGATAAAGAGACAAGCAGAAATCAATCGAAAGAGCAAGGAAAGGATTGCCTTTGACGAAGCATCACGAAATCTCACAGAAGACACGCACATCGTCAGCGGCGTCAGATGTGTATAAGAGACAGAGCTGAACGGAGTGATTTCGCGCAGCAGGATGGAGTTGGTCAGGCGATTGCAGCGAAGACACTTTGAACGCTTCCACGTAGTCAAGCGTTGCCGGATCTTTACCTGATCACGATGTTCTACTCAACCGCCCAGAAAGTTACAAACGCCAGCACTTCCGGTCTGAGCAAAGTTAGACAGCAGTTTCGGTGATGATCAGAGAAGCGGGTTATGGGTGATAGCCGGGGCGATGAAATCCGCACGGTACCATTTGGTTCCTGTGGATCAGCTGGTAGAACGCGTGCTGACCGTTAGTGCCTGGTTCACCCCGGATAATCGGGCCAGTCTAGTAATTCGACGTTACCGTTACAGTCAACGTACTTACCGTTGGACTCCATATTGCCCTGCTAGAGTACGCCGCGAAACGGGCCATATACTGGTCATACGGCGGAATCGCTTCAGTTTCGCGCCAAAGAAATTGTTGTACTGGATGCAATCAGCGCCAGTAAATCACGGGCAGGTTTTTCTCGGCAGGCGTGGTGGAGAAATGCTTGTCCATCGCGTGTGCGCCAGAGAAGCAGTTCAACGAAGTTATCGCAGAAAGCCGATGGAGAGAACAATCCGACAGGCCAATCATGACCATAAAGGTAACGACCACCGACCCAGTCCCCGGAGACTCGGGCATGTTGGCGGTATCAATGCAAACTCGCCAACGGCTTTGGCGTTGGTTAGGAAGCGCGCCGCAAAGTGATGTTTCGCAACGTGTTTTGCATCACCAGCCGCTTTCAGAACCAGTCACGCGCACTATGGGCGTTGGTCATGGTTTCCTGAGTGGTGAAGGTTTTAGATGCTACCAGAGTTGGCAATGGTTTCGGGTTTACTTTTTTCAGCACTTCCGCGATGTGAGTCCATCGACGTTAGAAAGTGCATGTTCAGGTGATTTTTGTACGGACGCAGTGCTTCAGCCAGTCTTTATGCCCATGGAGCCGAGTCAGAACCGCCGATCGATGTTCACTACGTCAGTGATTGCTTTGCCAGTACTTATAACCCTTCCACTCACCGGAAATAATCGCTTGCGAAGGTTTCATCTTCTCCAGCCCGCGTTGACTTCCAGCATAACGTCTTACACCCATCAAGCAGAATCCAGGGTATTGCTACGGACACGCAGCGCTACGTGCAGCACGGCGCAGTTTTCGGTGCAGTTGATCTTCTCACCAGAGAGAACATCGACTTAATCGCGCCCACTGAATCCGCACTCTTTCATAGATCTTATGAGTTCGCCAGCGTCTCTTCAGTGATGCGGTTTGGGTAATCCACCAGCATCTGATCGTCGAAGGTTGCGGAGAACTTAGAAAAACAGTCGCCGTCTTTAGCAAAGATCGGCGATCGTAACGTCTTTCATTTCAACTCAGGAAGTGTTTCTGTAGTACCTGCCAGGCAGCGGTCTGCGTTGGATTGATGTTTTTCATTAGCAATACTCTTCTGATTTTGAAATTGTGACTGGAAGATTAGCGCCAGTCACAGAAAAATGTGATGGTTTAGTACCGTTAGCGTAATGTGGCCGAGTAAACTAACAGCGCAGTGAAGCATTTATTAGCTGAACTACTGACCGCCAAGTGGATGAAAAATCCGCATGACCCCATCGTTGACAACCGCCCCGCTCACCTTTATTTATAAATGTACTACCTGCATGGCGCAGGCCAGAAGAGCGCGTTGCCCAAGTAACGAAGTGTTGGAGGAGCCAGTCCTGTGATAACACCTGAGGGGAGTGCATCGCCGAGGTGATTGAACGGCTGGCCACGGATGGCATCACATCGGCTACAGAGGCTGAATCCCTGATTGTCACCAAGCGTTCGCAGTCAGGCGTTTCGCAAGTGGTAAGACACTTCTGGGTGAAAATAGTAGCGAAGTATCGCTCTGCGCCCACCCGTCTTCCGCTCTTCCCTTGTGCAAGGCTGAAAATGGATCCCTGACACGAGGTAGTTATGTCTGGAAATTGTTGTCTCCAAGTTGGCGGGTACCAGCGTAGCTGATTTGACGCCATGAACCGCAGCGCTGATATTGTGCTTTCTGATTGATGCCAACGTGCGTTTAAGTAGTCGTCCTCTCGGCTTCTGCTGGTATCACTAATCTGCTGGTCGCTTTGGCGGAAGGCTGGAACCTGGCGAGCGATTGAAAAACTCTGACGCTATTCGCAGCATCCGGTTTGCCATTCTGGAACGTCACCGTTACCCGAACGTTATCCGTGAAGAGATTGAACGTCTGCTGAGAACATTACTGTTCTGGCAGAAGCGGCGGCGCTGGCAACGTCTCCGGCGCTGACGGATGAGCTGGTCAGCCACGGCGAGCTGATGATGCTCGACCCTGCTGTTGCTGTCGAAATCCTGCACTGAACGCAGTATTTCAGAGCACAGTGGTTTGATGTACGTAAAGTGATGCGTACCAACGACCGATTTGGTCGTACAGAGCCAGATCTTAGCCGCGCTGGCGAACTGGCCGCGCTGCGGCTATCACGCCTCAATGACGGCGAAGTGATCACCCAGGGATTTATCGGTAGCGAAAATAAAGGTCGTACAACGACCTTGTGGGTGGAGGCAACAGTTATACGGCAGCCTTGCTGGCGGAAGCTTCACCGCATCTCGTGTTGATATCTGGACCGACGTCCCGGGCATCTACACACCACCGATCCACGCGTAGTTTCCGCAGCAAAACGCATTGATAAATCGCGTTTTTACCGAAGCGGCAGAGATGGCAACTTTTAGTGCTGCAAAAGTACTGCATCCGGCAACGTTACGCTACCGCAGTACACGCAGCGATATCCCGGTCTTTGTCGGCTCCGGCAAAGACCGCGCAGGTGGTACGCTGGTGTGCAATAAAACTGAAAATCCGCCGCTGTTCCGCGCTGGCGCTAAATCGCAATCAGACTCTGCTCACTTTGCACAGCCTGAATATACTGCATTCTCGCCTTCCTCGCGGAAGTTTTCGGCATCTCGCGCGGCGTAATATTTCGGTAGACTTAATCACCACGTCAGAAGTAGGCGTGGCATTAACAACCGCCAGTACCACCGGTTCAACCTCCACTGGCGATACGTTGCTGACGCAATCTGCTGATGGAGCTTTCCGCACTGTACCGGGTGGAAGTAGAAGAAGGTCTGGCGCTGGTCGCGTTGAGTTGGCAATGGCTTCTGTCAAAAGCCTGCAGCGTTGGCAAAGAAGGTGTCAGCGTACTGAACCGTTCAACATTCGCATGATTTATTTACGGCGCATCCAGCCATAACCTGTGCTTCCTGGTGCCCGGCGAAGATGCGAGCAGGTGGTGCAAAAACTGCATAGTAATTTGTTGAGTAAATACTGTATGGCCTGGAAGCTATATTTCGGAGCCGTATTGATTTTTGCTTGTCACTATACTCATCAATAAACGAACCTGTACTCTGTTAACCAACATCTTTATCGGAGAATAATTGCCTTTAATTTCTTACATCTCTACGTAAATGCAAATGAAGAGATAATAAGTTAGGCAGGCAAGTGCAGCTCTATAATTGTCTATGAGCAGATTCCCGTACACACTGAACTCTCTGGCTCACTGGGGGCACCAGCGCTCCCCGTATTACCCAAAAGAGATGACTGAACGCGAGCAGCGTGAACTTAAAACACTGCTGGATCGGGCGCGGATTGCGCATGGTCGCTGTACTGACCAACTCCGAAACCAACAGCATTGAAAAAGATACATCGATAAAGTGGTCAGGCGTGAGGCTGAAGCAAAAAAAAAGCCCGCCAGTTAAAGAAAAAGCAGGCTTATAAACCAGCGGATCCACCAGAAGCGTCATTTAGCTGGTCAGCAAATGCGTCGACGCGCGGCAGGCGCAGTTAGCGCCCCTTCTTTTACGCCCGGCGAAGTCAAAAGCCTTACCGTTTGGACGCCGGGCGACCGCCTTTTTCCGCCCGTTTTCCATCATGTGGCACGACTGGACGTTTAATACCTACAGTTTTTCGGTTTGGCCTTCGCTTTAGGTTTTGCCTCGGAAGAGGAATTTTCAATGAGCTTAAAGAGGTCGATTAACTCATCACGTCAGTTAAATCACGCCATTCCCCAGCGGGAATGCCGCTTAAACTAACGTTCATGATGCGCGTACGTTCCAGCTTTTTCACTTCGTAACAAAGTGCTCGCACATGCGACGGATCTGACGGTTCCAGCCCCTGCACCGGGGTAATGCGGAAGACAAACTAACGCTTCTTTTTTGGCTTTACACTTTTTCGTCACCGTCCGAGGATCGCCTCCCGCCCCATACCACGAATGATTCATCGGTAATCAGTTTATCGACCGTCACCAGATACTCTTTCTCATGATCGTTACCGCGGAGGATCTTATTCACCAGATCGCTGTGATTGGTGAGGAAAATCAGCCTAAGTCTTTATCAGGCGGCCAATCAGGAACACGCGTTGCTGTGGTTAACGAAATCGACAATGTTATCGCGCTCGCCATCTTCGGTGGTGCTGACAATACCGACGGAGGCTTGTTCAGGGCGATAAGTACCAAATCTTCGGCTTCAGGCTCAATCCAGCTGACCACGTTTACTTTCCACAACGTCGCCGGAGTTTCACCTGATCGCCAATGGTGGCTCACTCGCCATTAAGGAACACATTGCCTTTACTCGATATAGCGATCCGCTTCGCGGCGTAGAGCAAGATTCCGCTTTCGCTGATACATTTGGCCCAAACGAGGCTGATGAGTCAGGCAGCATAAATTCTCCTGTAAAACGCGGAATATACCGTACCTCTTGGCAGGAAAAACAGGGTTATGCAGCAACGTCAAGAATTAAATGTGATCTGCCACGCCTTTTATCACAAAGTGTCTCCGGAAGTACGATGCAAATTTGCCTGGCAAAATAAGGATGATCAACATATTACGAACCACTGCACACCTTGCTACTGATGGCTACTACTGAAGGCTTCGATGTGCAGAAAGCGCTATTTCTCCCCCCATGCAAAGAGTGAAAAATCGGCACGAAGGCCATCATGATGGGGTTATATCAGATCAAGCCAGGTGAGAAAGCGTGTACACAAATGTACAGGAGAACCAGGAAGGCAGCAATGCAAACAGTGACGATATCCGTTTGGTTGTGAAGATTGCCCAGCTCTATTACGAACAGGATATGACGCGGGTGCCGTCGCGCGAACTGGAGTATTTACCGCACCACCATCAGCCGCTTGCTTAAACGAGGCCATGATCAGGGAATTGTCACCATCACCATCAACTACAACGAAATCTCTCTGACACCGACAGCAACTAAACAAAAAGTTTGGCCTGAAAGACGTTGTGGTGGTGTCAGGAAATGATGAGGATGAAGAGACTCAACTGGCGATGATGGGGTTACACGGCGCGCAACTGCTGGATCGCTTGCTGGAGCCTGGCGATGTCAGTTTTCCTGGGGTCAGCGCGGTGAGCGTGGTTTAAAAAGCTTTGCATTACCTGCCACCAGGCGAAGCAATCGCGGCAGTTAATCTGCGTACCAATTATTGGCGGACCGTCCAGCTGATAAACTCGAAAGCCGCTATCACGTAAACACATTAACCTACAGCGCGGCAGCAAGCCTGCCAAGAAGGGAATCGCATCTCTCGCAGATTTTCCGGCTCTGCTGGATAACCCCTTAATTCGTAATGGGATCATGCAGTCTCAGCGCTTTAAAACCATCTCTGCCTGGGATAATCTGGATGTCGCCCTGGTGAATTGGCTCACACCAGCCATTCGCGACAGCGCTAACGGCATGCGTTTTTATGATGGTGAAGAGAGTGACGACCTGAATGCCCGCCAGGTTGCGCTAACCCGATATTTGCTCGCACTTTTTTGATATTCGGCGCAATGGATTTGAAACGAATATGAGCGAAAAAAACACTCTCTATCGAAATGAATAAATTGAATTAAAGCAGGCACGATATTCCATTGGCATTGCCATGAGTGAAGAAAATACAGCAGGATTGTTGAATTTGCACTGCGTGAAAATATATTAATTGTCTGAGGTAACGAATAGCAGCACAGCTGAACTATTATGAAATAAAAATCTTCCCGATGTTTGTAATAAAAATTACGGCGGGTCCCTATTATCTAAAAACAGGAGTCTATTATGCAAACGTGGTTAAATTTGCAGGATAAATCATTATCGTCACCGGCGGCGCATCAGTATAGGTCTGGCGATTGGCAGAATTAATAGCACAAGGCGCGAATGTACAGATGGTCGATATTCACGGTGGCGATGGACAATATGAAGGTCATAAAGGCTATCAGTTTGGCCGACCGATATTTCCAGCGCGCCAAAGAGGTAAATCATACGGGACGAAGCGCGAGAAATATCTTCAAGCGTGCAGCCGTGAGCGATTATATACGATTGTTTTCCGAGGTCATTTACGCGTCATACTAAATAAATACAAGTAAGTGCGGAAGCGTATAAGAAAAAAGCATTACATTAGAAAAGTATGCGTGAATATAAAAGCCAGAAGCGTTATTACAGCATTTGCTTTTATGATGATGATAAATCTTTGCGACGGCGCGATGCGATCACGGCGCTACATGGAAATGTTTGGGAATGGAACTGGGCTCAGAAGCAATATGATGTGGAGCGGGTGTTTTTGATCTAATATGGTGATAACCTTTCTTTTTAAAAGATGGAAAAAACAGACATACCTTTTTCGCAGAATATATGAAAAGCTTTAATGACGTGCATGACCTACCATCAGAAGTGATGAAACAAATGGTGCAGGAGTGCAGATATGACGCGGAAACGACGAGAATAAATATTATTTGCGTGATACCTTTTTGCCATGCACTTTGGATGGATATGGAATATCGGTGTTTAGTAACATAAGTAGCAGGAAGTGAATGGGTGC
-+
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
-@6d856c07-ec15-4762-9942-42ee0ea19d57
-CAGTGTGGCTGCAGTCAGACCATCACTTCAGTACTCTTGAACCTCTCGCACATCGAGCTTTTACAATACGGCTGCTGCCAGTGGCAGCACCATCTATTATCTTACAAGGGTTGGACTCAAGACGATAGTTACCGGATAAGGCGCAGCGGTCGGGCTGAACGGGGGTTCGTGCACACAGCCCAGCTTGGAGCGAACGACCTACACCCGAACCGAGATACCTACAGCGTGAGGCTATGAAGCTGCGCCCGAAAGAAGGCGGACAGGTATCCGGTAAGCGGCGGAGATCCGGAACGGGGAGGCGCGGGGAGCTTCGGAAACACACGGTATCTTTATAGTGCCTGTCGGGTTTCGCCACCTCTGGCTTGAGCGTCGATTTTGTAGATTGCTCGTCAGAATGAACCTATCGACTTTTTCTGCAGCGCTAGCTACCTCAGTGCTTTGCTTTTGCTCACATGTTCTTTCCGACTTTATCCCCCGATTCTGTGGATAACCGTATTACCGCACGGTGAGCTGACACAACTCCGCGCCGCAGTCCAGACGACCAGGCGTAGCGTGTCCGTGAGCGAGAGAGCGGAGGAAGCGCCTTATGTGACATTTTCTCCTTGCAAGCTCTCTTGTGCCGTTCGGCATCCTGTCCTGAGCGTTATCTCTGTGCTATTTTCTACTTAAAGTAACGTGTCTGGATGCTGTTTCTGGAGTTCTTCTGCGAGTTCGTGCAGCTTCTCACACATAGCAGCCTGTTCGTCAGCATCAGGTGCGTCCCGGTTTTCCGAGCAGCGTCAGGCTCTGACTTTTGTAAGATCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCGCAACGGCTTTTTGACGAGCATTTCTGTCAGACAACACTGTCACTGCCAAAAAACTGCCGTGCAGCTGTCGGTAATTCAGGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCATACATGCACGCTATTGGTGCCCTGGTGGGGCTTTGCCCCGACACCCATGTCAGATACGGGCCATGTTTTATGACAAACGAAGTGGAGTAATACGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACAGCGAAGAAGACCAGGAAATCAGAAAAGGGCTGCGCTGAATGCGGCAAGACCGTTTCCGGTTTTACGAGGCGGCAGCTCTCGGTAAGAAAGTTAACTCGCACAGCTAATGATCAGTTACTGAAAGAAGTTATGAGACTGGGGCGTTACAGAAAAACTGCTATCGACGGCAAGCGTGTCGGGGACAGGGAGTATGCGGAGGTGCTGATCGCTATTACGGAGTATCACACCGTGCCCTGTTATCCAGACTTATGGCAGATTAAGCTTCCCGGAGAAAACTGTCTTCGAAAACAGACGGTATGAACACCGTAAGCTCCAAAGTGATCACCATTCGCTTTCATGTAGCTATGCGGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCCGGGGTAAAACATCTCTTT
-+
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
-@f88b7d0e-f11f-4266-b417-c466054eca05
-GTTGTACTTCGTTCAGTTACGTATTGCTGCGCGCACTCTCTGGTCTCGTGGGCTCGGAGATGTGTATAAGAGACAGGCTGTAGTCAGGCCATCACTTCAGTACTCTCACCAGACCTCTCGCACATCGACTTTTACCAATGGCTGCTGCACCAGTGGCGCTTTGTCGTGTCTTTGCAGGTTGGACTCAGACGATAGTTACCGGATAAGGCGCAGCAGGTCGGGCTGAACGGGGGGTTCGTGCACACAGCCCAGCTTGGAGCGAACGACCTACACCGAACCGAGATACCTACAGCGTGAGCTATGAGAAAGCGCCACGCTTCCCGGAAGAAAGGCGGACAGGTATCCGGTAAGCGGCAGGGTCGGAACAGGAGAGGCACTTGCGAGGGAGCTTCAGGAAACACCTGTGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTGCCTGGCAGGCGTGTTTTGTGATGCTCGTCGGGGGCGGAGCCACATGGAAAAACGCCTGCGGCGCTGGCTTCCCTCCGGTGCTTTGCTTTTTGCTCATGTTCTTTCCATTTATCCCCCGATTCTGTGGATAACCGTATTACCGCTTTTGGTGAGCTGACACCGCTCGCCGCAGTCGAACGACCGAGCGTAGCAGTCAGTGAAGCGAGGAAGCGGAAAAGCGCCTTATGTGACATTTTCTCCTTACGCTCTGTTGTGCCGTTCGGCATCCTGTCCTGAGCGTTATCTCTCTGTGCTATTTTCTACCTCCAAAGCGTGTCTGGATGCTGTTTCTGGAGTTCTTCTGCGAGTTCGTGCAACCTCACACATGGCAGCCTGTTCGTCAGCATCGGGTGCGTCCAGTTTTCGAGCAGCGTCAGGCTCTGACTTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTTGACGAACATTTCTGTCAGACAACACTGTCACTGCCAAAAAACTGCCGTGCCATTTTGTCGGTAATTCAGGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCTGTACGCGCTATTACAATTGCCCTGGTCAGAGACTTTGCCCGACACCCATGTCGAGATACGGAGCCATGTTTTATGACAAAACGAAGTGGAAGTAATACGCAGGCGGGCTATCCAGTCGCCCCTGTTCGTCCTGACGGCAGAAGAAGACCAGGAAATCAGAAAAAGGGCTGCTGAATGCGGCAAGACCGTTTCAGTTTTTACGAGCGACAGCTCTCGGTAGAAAATTAACTCCACTGACCCACAGTGATGATCGGGTACTGAAAGAGGGTTATGAGACTGGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCAGGAGACAGGGAGTATGCGGAGGTGCTGATCGCTATTACGGAGTATCACCGTGCCCTGTTATCCAGACTTATGGCAGATTAGCTTCCCGGAGAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGCTGTCTCTTGCTACACATCTGACTGCCGACGACAGA
-+
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
-@e26f1e29-f581-4bde-b347-48fe72ec276b
-AAAGAGATGTTTTACCCCGGGAAAACAGGAAGGATGCGTCAGGATCGTTTTCAGCTCGCTGCATATAGCTATGCATGAAAGCGAATGGTGATCACTTTGGGAGCTTACGGTGTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCGGAAGCTAATCTGCCACAAGTCTGGATAACAGGGCACGGTGATACTCCGTAATAGCGATCCAGCACCTCCCGCACATACTCCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTTCTGTAACGCCCCCAGTCTCATAACTTCTTTCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTACCGAGAGCTGCCGCCCGAAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCCTTTTTCTGATTTCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATAACCCGCCTGCGCGTATTACTTCCACTTCGTTTTGTCATAAAACATGGCTCCGTATCTGACATAGATTGTCAGGCAAAGCCCTGACCAGGGCAATTGTGGCAAGCGTGCATGTATGCGCGGTATAACAGTGCACATCCTGTCCTGTCAACAGCTCGAATTACCGACAAAGGCACGGCAGTTTTTTGGCAGTGACAGTGTTGTCTGACGAAATGCCGTCAAAAAGCCAAGCGGCAGAATAACGGCAACAAAACAGTCGAAAAGTGGTACGCGATATAATCACACAACGCGCAGATGACAGACAGAACGGAGAAAACGAAAAGATGAACAAGCAGCAGCAAGCCATTACTCAACATGGCGGGATTCATAAAAGTCAAGAGCCTGACGCTGCTCGAAAACTGGACGCACCCGATGCTGACGAACAGGCTGCCATGTGTGAGAAGCTGCACGAACTCGCAGAAGAACTCAGAACAGCATCCAGACACGCTTTGAAGTAGAAAATAGCACAGAGAGATAACGCTCAGGACAGGATGCCGAACGGCTACAACAGAGCGTAAGGAGAAAATGTCACATAAGGCGCTCTTCCGCTTCCTCGCTCACTGACTCGCGCTACGCTCGGTCGTTCGACTGCGGCGAGCGGTGTCGAACTCACTCAAAAGCGGTAATACGGTTATCCACAGAATCAGGGGATAAAGTCCGGAAAGAACATGTGAGCAAAAGCAAAGCACCGGAGGAAGCCAGCGCCGCAGGCGTTTTCCATAGGCTCCGCCCCCTGACGAGCATCACAAAAATCGACGCTCAAGCCAGAGGTGGCGAAACCCACAGGACTATAAAGATACCAGGTGTTTCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCCGCCTTTCCCCCTTCGGGAAGCGTGGCGCTTCTCATAGCTCACGCTGTAGGTATCTCGGTTCGGTGTGGGTCGTTTCGCTCCAAACTGGGCTGTGATGCACGAACCCCCGTTCAGCCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACAAAGCGCCACTGGCAGCAGCCATTGGTAAAAGTCGATGTGCGAGGTTCAAGAGAGTACTTGAAGTGATGGCCTGACTACAGC
-+
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
-@20d5d0fe-d078-4b07-ac2c-a435d65fdd5f
-CTTCGAAGTACTCTCTTGAACCTCTCGCACATCGACTTTTACCAATGGCTGTTGCCGGTGAAACTTACATCGTATCTACCGGGTTGGACTCAAGACGATAGTTACCGGATAAGGCGCAGTCAGGCTGAAGACAGAAGTTCATTCACACACAGCCCAGCTTAAGGCGAACAAGCCTACACGAACCAGGAATGCCTACACAGAAAGCGTGAGCCTTCCATCGAGAAAGCGCCACGCTTCCCGAAGGAAGAAAGGCGGACAGGTATCCGGTAAGCGGCAGGGTCGGAACAGGAGAGCGCACGAGGAGCTTCCGGAAACACCTGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTCTACGGCAGGCGTCGATTTTTGTGATGCTCGTCAGGGCGGAGCCTATGGAAAAACGCCTGCGGCGCTGGCTTCCCTCCGGTGCTTTGCTTTTGCTCATATTCTTTCCGACTTTATCCCCAGTTCTGGCGGATAACCGTACGCTTTGGGTGAGCTGACCTGTCGCGCCGCAGTCGAACGACCAGTATGTGAGTCGGTGCGAGCGAGGAAGCGGAAGAGCGCCTTATGTGACATTTCTCCTTACGCTCTGTTGTGCCGTTCAGCATCCTGTCTGAGCGTTATCTCTGTGCTATTTTTCTACTTCAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTGCAGCTTCTCACGCTGGCGACCTGTTCGTCAGCATCGGGTGCGTCAGTTTTTCGAGCAGCGTCAGGCTCTGACTTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCATTTTCGTTTTCTCCGTTCTGTCTGTCATCACGTTGTGATTATATCGCGTACCACTTTTCGACTGTTCCACTGCCGTTATTTCTGCCGCTTAACTTGGCTTTTTGACGGGCATTTCTGTCCAGACAACACTGTCACTGCCAAAAAACTGCCGTGCGGTGTCGGTAATTCGAGCTTGCCTGACAGGACAGGATGTACAAATTTGTTAATACCCACTTTGGCACATGCGCTGTACAATTGCCTAGTCGAAACTTTGCCCCGACACCCATGTCAGATACAGACCATGTTTTATGACAAAACGAAGTGGAAGTAATACGCGCGGGCGGGCTATCCAGTCGCCCTGTTCGTCTGACGGCAGAAGAAGACCAGGAAATCAGAAAAGGGCTGCTGAATGCGGCAAGACCGTTTCCGGTTTTTACGGGCGGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCGGGTACTGAAAGAAGTTATGAGACTGGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCAGGGACAGGGAGTATGCGGGAGGTGCTGATCCTTTATTACGGAGTATCACTGTGCCCTGTTATCCAGACTTATGGCAGATTGGCTTCCGGAAAGCTTCGTAAACAGACGGTATGAACGCGTAGCTCCCAAAGTGATCACCAATTCGCTTTCATGTAACTATGCAGCGAGCTGAAAACGATCTGACGCATCCTTCCTGTTTTCCCGAAGGTGAAACATCTCTTT
-+
-@A9,&/&8<:9<<9=?@@?EDB@/4A34:H@BG>?@GGF@98<34C29@A838+.:$/*)%&$$%%#$$('$$$.),*67%&->:8;9;;>4550&//;6<FFEEIBDB3::643-%'*('$)+,,--.)4,$%&$=;/)$#$#%.--1/1,98'$/&&&#%%,-%$%#$'$7610'02%%&')%))$($$--+'&*2&&--*0-(''$'%%'''())+%%$)2+/<<CC5A;9==4:))%%-//2*20&3?@<?>.(-0@=9;E;;<;;;>461,1,0-@AFJE-9(5:3+4@23/0-+>73>>></4%&$(;:2<<8'):>;>::4333544;9,'E2;IDIBDHIGC6<+3#"(11.%.<C??CFBKFDC<0554;.%3=;92)7+21&)%*-,/)88<87788<5779>@165101%%"#$&(.0',2;D>//0=4...56*(+*%#%$%#$+337629:<1(,,1/.)-+&**''%(/==:;1+%$%,1+++-(+700-71+/+%%%&,($'9?@6)&/)=))079><6.4496(1++&.9$%1(),*./0001-4+8>>=@4:,D:34*)(-+1429*/83;8(/'*,EA@*:(:33-,&'+,47*%:28++05-(1)')'/+26<;4=DCBH@@G@BBCB></*/11,%&0??9=8>016DDDCBB>75225/;A?5IB?A9<77AB2/*D751=9;A?.>*0%$/(((%$21(&$%&''0+66'%@(.@FBG($.#*66ED8?52953<<993&';>==9D=9:<NM<50**19;HD>DD99:76,-06//3/%>>CCE<;?97=>>5+,&&,#)015>7;956/(*4%23+-+(7&(/-+,&$'$%+$,..16;;=<?;;7;@BD@=?@E>*05113?4%&&*84149A;3999/---+%#$$#$"$%*3677887811%&:>;?B0--$&'4)+*&2149771:=885*)5<=545;9CA@>:?63&'+246%)423138**1*3644%6;*/+;>1146042*&%)$&$'.)$#'*+0345,$$&&'%()((*&%,'')&++3'*'0566*$%).+-,.66729BBAAAA@73--45.,/'-2&%+$)%783:9<;<,%(&*)(,$%.)')16784/0<@?946-'-5'*5<(**),)&&5,,:;@GF@D?EC?=:CALFH8=0,,,-.:2C?@:6:3/1?5A=9<3''%0=8BA=3?9?@?F19D=>4?AC;GE@(../)67686;/29:)062?D?84B(19784681>CH=>@HA<9CLI?@CADA<9C/36EJ@A?=@2,;2<67,'',@<BB16:;:5/+66655..7<AAA>?8;C@@CDGG%-AB;8?;>>;2*8666*-1+9/;@@:63%*,3*@D=<CD>''/')72056>24(6<)%0$%#',+57451*,$$$+*')331'*&&&./0:;%-2251.+0(+.$%%*.'&(,&497BA/5;,*&&'&&%&'*+<969;9;68>5641$$%$(,+2($&(+*%#$$))22495718811A;;A@G<;@;<9@;JBJA>::;?;B<?FA?>ME47+1(''(**+6435:==5<<J
-@7b2e15ef-cb18-4008-84f7-5447fe763f8b
-CTCTTGAACCTCTCGCACATCGACTTTTACCAATAGGCTGCTGCCAGTGGCGCTTTGTCGTGTCTTACCGGGTTGGACTCAGGCAAATCGCCATTACCGGATAAGGCGCAGCGGTCGGGCTGAACGGGGGTTCGATCACAGCCAGCTTGGAGCGAACGACCTACACCGAACCGAAATACCTACAGCGTGAGCTATGAGAGAAAGCGCCACTTCCAGGGAGAAAGGCGGCCGGTATCAAGTAACGGCAGGGTCAACAGGGGAGGCGCACGAGAGCTTCAGGGGGAAACACCTGGTATCTTTATAGTCCTGTCGGTTTCTTACCACCTCTGGCGAGCGTCGATTTTGGCGGTGTGCTCGTCGGGAAGGTGAACCTATGAAACGCCTGCGGCGCGCTTCCCTCAGTGCTTTGCTTTTGCTCATGTTCTTTCCGACTTTATCCCCGATTCTGTGGATAACCGTATTACCGCTTTTGAGTGAGCTGACACGCTCGCGCCGCAGTCAGATGACGAGCGTAGCGAATCAGTGAGGAAGCGGAAGAGCGCCTTATGTGACATTTTCTCCTTACGCTCTGTTGTGCCGTTGGCATCATAATACAAAGGCGTTATCTCTGTGCTATTTTCTACTTTAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTGCAGCTTCTCACATGGCAGCCTGTTCGTCAGCATCGGGTGCGTCCAGTTTTTCGAGCAGCGTCAGGCTCTGACTTTAGATGCCATATTTGAGTACGGCTTGCTGCTGCTTGTTCATCCTTCGTTTCTCAGTTCTGTCATCTCATCTGCGTTGTGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCAGACTAATGCCGCTTGGCTTTTTGACGGGCATTTCTGTCCAGACAACACTGTCACTGTAAAAAACTGCCGATGCCTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTTACAATTGTTATACCGCGCATACATGCACGCTATTACAATTATGCCCTGGTCAGAGCTTTGCCCCGACACCCATGTCAGATACGGAGCCATGTTTTGCCAATAAAACGAAGTGCGATAATACGCGCAGGCGGTATCAGTCGCCCTGTTCGACGGCAGAAAGACCAGGAAATCAGAAAGGGCTGCTGAATGCGGCAGGGCCGTTTCCGGTTTACGGGCGGCAGCTCTCGGTAAGAAAGAAGTTAACTCACTGACTGATGATCGGGTACTGAAAGAAGTTATGGGACTGGGGGCGTTACAGAAAAAACTCTTTATCGACGGCTTAAGCGTGTCGGGGACAGGGAGTATGCGGAGGTGCTGAGTCGCGGACCCACTTTTTACAGTAACAGTGCCCTGTTATCCAGACTTATGGCAGATTAGCTCCCCGGAGAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCTTCACATAGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCAGGGTAAAACATCTCTTT
-+
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
-@41289833-2fcb-408d-bfa9-181ed6bfcaae
-GTTGTACTTCGTTTCAGTTACGTGTGCTTCTGTCTGGCAGGCTCGGAGATGTTATATAAGAGACAACCGTATGCCACCTCCGCGTACTCTCTGTCCAAACGCGTCGATAAAGAGTCTTTTCTGCAACACGCCCCCAGCCTCATAACTTTCAGTACCCGATCATCCAGTCAGTGAGTTAACTTTCTTGCAAAAAGGCTGCCGCCGTAAAACCGGAAACGGTCTGCATTCAACGACCACTTTCTGATTTCTGGTCTTTCTGCCGTCAGACGAACAGGCGGCGGTAACCCGCCTGCGCGTATTACGCCCCCACATGTTTTGTCTAAAACATGGCTCCATGTGGCATGGGTGTCAGGGCAAAGCCCTGATAGATTATACCAATAGCGATGCATGTATGCGCGGTATAACAATTACTCCCTGCCTAATCAGCAAGCTCGGAAGTACCGACAAAAACACGGCAGTTTTGGCGACGGTGTTGTCTGGCAAATCACGTCAAAGAAAGACAATCACCGGTAAAACGGTCGAAAAGTGGTACTCGTCGTAATCACAACGCAGATGACAGAAAGAACGGAAGAAAACCAGAAAGATGTGAACAAAGCAGCAGCAAACCGTACTCAACATGGCGGGATTCATAAAAGCCAGAGCCTGAGGCTGCTCGAAAAACTGGACGCGCGAACGGAGCCACTGTGAGGAAGCTGCACGAACTCAGGAAGAACTTCGGAACAACATACAGACACACTTTGAAACGGAAAATCGCACCGGGATATAACGCACCCGGACGGGATACAGAACGGCATAGCGGGCACGTGGGAAAATGCCACATCAGACTGCTCTTCGCTTCCCACTCGCTCACTGACTCGCTACGCTCGGTCACGTTTTCGATGACGCGGCGAAAGGTCATCAGCTCACTCAAAGGCGGTAATACGGTTATCCACAGAATCGGGGATAACGCCGGAAAGGAACATGTGAGCAAAAGCAAAGCACCCGGAACAAACCAGCGCCGATGCCGTTTTTCCATAGGCTCCGCCCCCTGACGAGCATCACGAAATCGACGCTTCAGGTCAGGGTGGCGAAACCCGACAGGACTATAAAGATGCAGGCGTTTCCCCCTGGAAGCTCCCTCTTGTTCGACCACCAACACCGGATACCGCATGCCTTTCTCCTTCGGAAGCGTAGCGCTTTCTCATAGCTGCGCTGTTTGGGTATCTGGTTCGGTGTAGGTCGTTCACGGCCAAACTGGGCTGTAATGCACGAACCCCGTTCAACGACCGCTGCACTGCTATCCGGTAACTATCGTCTTGAGTCCAACCCGGAAAGGCACATTGCACCACTGGCAGCCATTGGTAACTGAGTTAGAGGAGTTGAGTCGGGAAGTTATGCACCCCTGATAAGGCTAAACTGAAAGAACAAGTTTGGCGACTGTACTCTCCAGCCAGTTACCTCAGTTCAAAAAGGCGCCAGCTCTATGAACCTTCGAAAAACCGCCCGCAAGGCAGTTTTTCGTTTTCAGCCCAGTTGAACGATATCTTTGCTTCGTCAGCAAAGCCTAACGACTTCTAGCCCTTCCCGCACAGGCTGTTGTAACAGCTCGCCGTTGGGCCTGGCACAAGTACCATCTTTGGCGGGAATAATCACGCCCAGCAGGCTCTCATGACATCATTCTTGATCTCCATACTTCTCGATGACAGAGCAGAAAGTCTGTCGCTCATGATTCTCCCCAATTTACAAACAAAGCTCTTTGTCGGGAATCGCTCTTCAATGTATGGGGGCATAAGTCAAGTCCACAGTGGTATATTAGCTATATCATACTCATCATTACACGCACCAGACATAGACTTATAGCCAAATTAACATCGGACTCTTTTTCTTCGCCTTGCTGGAAAACTCCACACACCATTATCAGCTTCGCACGTTACATTCTTTGCGACGTCCACCGATAACATCAACACACATTCGGTTAAAGCGTTGGTGAAATTTTGATAATTTTCATTTATGGCTCTTGATAAATGAAGTGAAAGCAGCGGAAAACCAAAAAACGTATCAATGAATACATTTTTAGGAAGGTATCTCTTGCGCATGAATAACCCAATGAAAACTTTATTACAGTCTCTTCAATTGCATGATATAAGTATACCCATCAATAAAGCACCGCCAACGCGTTTTCCGATTTACTCAGTGTTTGTTGGTTGCTTGCTCTGTTTCATCTTGCCATTTTGACCTCTAGATTGTAAAAGGCTGCATATGGTACACATCACCTGGTTAACAGTTGTGCATGGACGTATCAAACCACGGAAGTTTGCTTCAAGTGCAAACCTCGACTTGGTTAACTAAGAACATAACTCTGGTGATGATTCAACAGTTCTGTAAAGAGCGATGATTTTGTGTGTTTATGTAATATAAAGAAGATCACCATGTGCTACCTGACATATCACGTGTAAAGGGTAGTTTAGGTGTAACTGTTCTGATTTTCGCGAGAAAGCATCTATGAGCACAAAAAGAAACACAGAAGAACAAAAAAAGGGTCATTAATCACTACTCACTGGGAGATGGTAACCAGCACATGGGTGGACAGCTATACCAAATAGCCTCCTTATGCTCAGGTGATCTTGGTATTGGGAGTACTGAGATGTGTATTCTGCTGAATATATTGATGCGTAGCCTGAGTCAGGGGAGTCAATATCTTTTCCGTCAATTGGTACCATTGCATCAAGAATAGGTGTATCTAAAAATTCAACATAGGTTAGTAACCTGGGGAGCATTAGGGATATTAACTAGATACCAATGTGAATGACCCCTCCAACAATAGCGCTAATATATATTCGACTCAACTCCTCTAAAGAATATTAAACTCAAAGTAGAGCATAACAATTAGCAACAGCAACAAAAGAAAGAAAAGAAAGAAAACTGAATTACTAACATAAAGAATTACACATTTGCCCAAAATGTTTGAAAACTAAAACAATAATATGAAGAGATTATTAGATTTTTGGCGTGCGAAAAACAATGGCTGGAAATAATAATTCATAATGTGCAAAGAATGCGAGCTGAAAAGATCTATTTTAAACAGTTGCTGGTATTTTTATGTAGCCAACTGCCCCATATTAAATGGGACATTTCAACGCTCCCATTTACCATAACGATCTCATTACGCGCACCGCAGAGCGCGCTGAACGCGATTCTGCGGTTGCACGTATAATGAGACGTTATGTCAGAACGTTAAATGATCGTACAGTGAAACGGTGACCATATAAAATGGTCAACTTTGTTAAAACAGATCTCGCTTTCAGAGAAGCTCGTCTTTACGATATGAATTTGTGTCCCAGCATACGTATTATTGTTTCGCGCATAAAGTTCCCATTCAAATGAAGGGCATTATTATTAACGGAAGGGAAGTGCCGCCTGGTTTCAGGCATTTTGAATAATCGTAATTACATGTTGAACAATTCCAGTTTTCTTTTCTTTCTTTCTTTTTATTGCTGATGCCCTTCCAGCAAATATTCTTTTAGGGATTGAGTCAGTATATTAGCACTCGTGTGGAAGGTCATTCACTGACAGATATCTAGTTAATGTCCCAATGCCCTCTAAGAAATATTTAAACAAAAAGCTAAAGGAAGCAACAGTGCCAAGCAACCCGGCAAAGAAGAAAGAAGAAAGCTTGAATTCCTTTAATTGGCGTAAAACATAAATTACCACCATTTTCAAGATGTTTGAAACTAAAACAACCAATAAATTTGTTTAAATTTTTTGGCGTGCGAAAAACAATGTGGGAAACCGTGAAAGTTCATATTACAAAGAATAGGCTTCTGGAAAAGAGATCTATTTTAAAAACAGTTGGAAAGCCTGTTTTGCTAGCAAGTAAACTGCTTTTTATAAGTAAATGGGACTGTTTCTTGCTCCATTTTTTCCATATTACATCATGTTACCACCGCGAAGCGCGCTGAACGCGCCGCGTTGCGGTGCGCAATGAGACGATCGTCATCGGGCGCTATCTCTTCGCATGCCATACTCTACACATCTGACGCGCTGCGGCGGTATTGCCATATATACAACCAATGCGTA
-+
-%,//-)$$$"#.0,-+064-)%/&.+,-0.((((%$%$%)19-;27645..$''%&$%%(&/&9%%;81++&$*0/007%0#&$$$$+&,400''2%($--.'+13659:7')26886884.*))'(&+.4598.4+441:),)'&,4;=:=53@>?@?BG=%%=24)'%*/'';66;<@LL:875%-*,9*%-,554<=2238;=>==<?&)-.+:+.+&$$6//34%&'%$$%$%//45121><6'6<<32,*'/11<?74B9=B@334.-(-2,-.).4()347;873+//1,*+'&$)*,,022%$%'.%'))'(($35879+.-244'3('&('&$$-%*/B-(/$.5.4:;:755(&&+%#%#$((('(*33388>$$9.9&&&%)&&+(*.1176/+@68681946>6:<>?>%%8.)28+,'%'2#&%$$$#(+..:4522%/$)-40):<52)*/09,5&.?EEE6/A,$$*%%$$#$955900$'%%$-'0%($$&,.'++.0.(:12'2*,,,+-9//(%#$(#$$$&6,%;(+))-(?AAF=84*.+56$66/558%(&274/%%%%.1,.2.+,)(.9.04'-.'4'''=@><0(87:8?64101/16/3@;DE=))9:A0,&''(&'888757>=D;:B;;:9B@A=?@B61%'2/-+)1%)%03-&&,''*'44%+%+-$'',+)256-&79+-+),)*)($'%,4()(&&*'%(&'$%""$&'+)&$-/1/..))'%'&&)*0CDA3+>@:>A<-F>14,1%)7+%%&%&*/<49>10/36))))%)%&$'2%(34%%'*%/$)(')5%$'.497.-(&(('02%&/?/<:;/53:7(.;**($)*,+0'061$88:;D550.'&&)$/$&'&&%&')%$#'83182?('1@56*(<?3794987@/100300:6CA<;92?+1;45=>==<9?2838'2)352)))(*&&4@@7%'?78//:(;BB()(6<:<'A692?>>://G@GB:@BEAB=?6'$4:992;6<99-*2<301,21&8=@:01A:655..)##$&&&451+8)9ADEB@>?/GIDA?*%4=4423/443353%+%7*59<>)564.''14737<;:?764*)(/+61)$)%%&$$$55>AD<*&,2%($&$&'&&-%/293/9%()/3'*'%7<3--8A?:;'&.'+(%/.269///%',)-.7''*%.)'(=7)1+:9?>B4+%&#%$&'+%77;1;61&%$$$'*&(**2ADA5=G+4$%(*'(4&&+$%&-,'(-2$$;&-5..7?A>?836.297>11B778;:'*'($&%206$$%#$#%%$(%)*,+4@B;<@38412*&'$'+35.+*(-3.52.857&*?41/:;7-,)+4,,)67=>782256@CA;.2&0.%=B;978DHD751%$%4,*%#$&,%3118:2?<9210,0+9?31CB10$+-:33,4'<69,32'';;>@:3-2A7:8:-32,$&&0253($+)+(('+'256..5&*(%$$#%%$$#$('%%%$$%%##%),),2&-*,.$+$(778778:493>0=;78>4('-,(*(&''+%(*&&$%%+'-96%%(&(&#&%&($#&#$&-.)*'/01:9??;.(($'$,*'$((((&&%%&((*'.1;81.,%%((($(31>1*&'&*8><&@177=ACE30;=AF<922/(*%$))(+,*/06<,,86++-,49595642#%#$.$%')&,232&612//0)$%#*;<<:8$$',&&'#$%%(47.112?>=:.0,'4')$'&.''$'(%%%*%&$%&,38@>42:+))027+9A:;=@@$%:?67/(;03%,00:8B1'(0&)-787BD>>G.(B<AC@;>78??BCC53$#$#%&(%***+-+)'+2'+&$%$$##%204,>>DE=8<.)-*-+30:?998%$,)<.+**/(**56?:;;<:B56@*;;DAC46-139;><7?>H801)()*)(*)'.,1...0+-%%/1.%')2DF?<:616.0-&&''$%()))$)$$+7;4=ID2:GF?761)$4-(398/&%(#&1')096.,0377<5BB;<3=B@+2((,&(%,)+)'118><A=.%+<CC>99;+645498FB2A<=9>DF?CDBCCB56+<<;<EDD@;D89<>@:$+%$&$$&--/&'#&*+&$(&%,.&%$0+%&/+(*0,6;03)+'$$''&44-+:810'%(&55:<:BDO>;7/+05/&&)%'%%42-%.,4/,-'%%##&$#$#'&%(%##%$&%'&&&&$#$$$#%')#&$'$%#%($%$%%$%#%%%$$&'$"$&%#$#&#%'($+&+*&&$$'#%#$#$$$+,$%$$$$%&$'-&#$'(#%)%$&%''&$)))',$../*%$%$$&&'$,---%($#%&))&$$$$%$$$&)&$(%')%&##%,''%$#%%)&'$$"#&&*'$$'%%)&($%&'&$%$&'%&&.$$%%&*$)&)&54BAQ:5)+,+,+')',4;>CB==;8763BB-&%%,,'/;=76>='=:-&*(('&&'/.**)03DC:A:75./38)(;*-&)061%%&$%%)/#%/.9;-/*>@BC0(+<;@=>.?=?=49.512'.'*64---#$&%*,($%%+/0878:25%.2:B<<=7<A>5825%%(8<87GGEFBB>>C><-&*(*)$***-,-:93-:0//57:?2/,*$$$+8;<=:@C9::>00/9><1.00?;7@44/9;57440((8797>A@18<=8//3&&&&($.,),1123*&)&'%%$&%*)65@B;9161?706+:4302+*%#$$%-(,(-32)+$+&&2))''-204=<?ADC99?CC889:DC/1<>&-+;7>?-'8,''.)-/*$&1,-)$%(&&*)2.32677256,601,D%=<2;@A3$986$@AA81)3,'3004/&%%$/23,$$))(%'$'%$''$$##%-().=./11./)0**.0/'(,89557:3)22,$'($%#%.,&&$$$)$.'-)5BCA@>24/,9&&+.8762*+,.)),+%'%&*($$&#%$')''((''$-.77'*+-1,-%%/1/03=0+4;7@;=9;A9:<@4.214*###$%444221-&%$$*'(,-26/7776&&&(,+,,3%+6(-,78,'%%&$%'$/+*6=@9A@2;886$$-.%6)*.6>.0(,378))'&'%3((238:5?<++8:@C=>:817%('&$%$%$%&'/1)'/.'111++()(3,+342/(($$%$%+%(')$&%(%%%)#$%$'$%-2:<784.&11.0$%$%'()4456:1,)3.'5#2#$132/+*&&)*$#%'$&%%'(%+%$*'&*$%(+,$*$%#%%#'$$%'(%&#$$#%*,-034..'%$((*%$#%#$%$#$&%&$##%%$$%$%$'%)((#%##$$&&(&))%$%'#')&$$$$*&().(%$**01/-,()'"$%%&'%&%&$%'$''+)&'.)+(,&+&-)**0-../2,01/,,-1**-0/+%%'&'-.,,&((&$$%&125791;>>9589;51209&(***+&-&%),))(*)+-+%&)-81$$&#%'%&&,)*-$#'&$'$$).234-&&#$%%#%**,**,-,-.++37,.-5/644<60')4.33(%%()*/0*(*%$$$$'#$$2&##&'++..-1.)-3>=./*2'*&&+,%'.(-$$$$$$&+.$%$(*%%$(#$#$%%'(%&&)*,007645*('%%$$%$$%%'%,45/*+(%.,358%0+*/.*,*%'115*#/24/0-566664#$%%+')$%%%%$#)($#&+*',,%#$#+%''('0.('%*#&&2-/%)&(&%&%#$&'..0153-)/442?1,++)&6751%%$*&0#%(0-$##))3894&'*(#$#%((//'-,&#$&&'(#$&((,'.771421')$$(3/02124$.)#*21.-%&*&&#$$$%%%$$$+%##($.2.3(()'&08:87756/*$)%$$&*%(-4--6.-%$')&)$(&&$#%%$%$$*+$)*&'%+(&&)+'('$####$%$%&$%&$%+.13-3'(%+(%159,.$&(%)(&$%$##'&,',,+1+,%*''&%+-*%
-@af596450-fce9-4cbe-9c93-96cd9a2a4fcf
-TGTTGTACTTCGTTCAGTTACGTATTGCTGCGCACTCTCTGTCGTCGGCAGCGTCAGATGTGTATAAGAGACGGTTACCGGATAAGGCGCAGCGGTCGGGCTGAACAGGGGGTTCGTGCACACAGCCCAGCTTGGAGCGAACGACCTACACCGAACCGAGATACCTACAGCGTGAGCTGTGAAAGCGCCACGCTTCCCGAGAGAAGGCGGACAGGTATCCGGTAAGCGGCAGGGTCGGAACAGGAGAGCGCACGGGGAGCTTCGGAAACACCTGGTATCTTTATAGTCCTGTGGTTTCATACCTCACAAGCAGGCGTCGATTTTGTGATGCTCGTCAGAGCGGAGCCATGGAAAAACGCCTGCGGCGCTGGCTTCCCTCCGGTGCTTTGCTTTTTGCTCACATGTTCTTTCCGACTTTATCCCCCGATTCTGTGGATAACCGTATTACCGCTTTTTAGGAGTGAGCTGACACCGCTCGCCGCAGTCGAACGACCGAGCGTAGCGAGTCAGTGAGCGAGGAAGCGGAAAAACACCTTATGTGACATTTTCTCCTTACGCTCTGTTGTGCCGTTCGGCATCCTGTCCCTGAGCGTTATCTCTCTGTGCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTGCAGCTTCTCACACATGGCAGCCTGTTCGTCAGCATCGGGTGCGTCAGTTTTTCGAGCAGCGTCAGGCTCTGACTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTTGATTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGCCTTGGCTTTTTGACGGGCATTTCTGTCAGACAACACCGTCACTGCCAAAAAACTGCCGTGCGGCTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTGCTGGTGTTATACCGCGCATACATGCACGCTGTACGTTGCCC
-+
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
-@7af2b230-ca5b-46e4-a171-332b9ab0351f
-GTTGTACTTCGTTCAGTTACGTATTGCTGCGCGCGCACTCTCTCTGTCGCGTCAGCGTCAGATGTATAAGAGACAGCTTTGGGGCTTACGGTGTTCCCTTACCAATCTGTTTCCAACCAGTTTTCTCTCGGGAAGCTAATCTGCCATAAGTCTGGATAACAGAACTGGTGATACTCGTAATAACGATGCTTCCTCACCATACTCCCTGTCCAAACACGCTTGCGCGTGCGATGAGTTTTCTGTAACGCCCCAGTCTCATAACTGCTTTCAGTACCCGATCATCAGTCGGTGAGTTAACTTTCTTACCGAGCTGCCGCCGTAAAAACCAGAGCGGTCTTGCCGCATTCAACAGCCCACTCTGATTTCCTGGTGTTCTTCTCTGCCGTCAGACGAACAGGGCGACTGATAACCCCGCCTGCATGATATTCGCTTCGTTTTAAATGCATAAAACGCTGGCTCCGTATCTGACATGGGTGTCGGGGCCAGCCCTGACCAGAACATTGTAATAGCGTGCATGTATGCGCGGTATAACGGTTGCACATCTGTCTGTCAGCAAGCTCGAATTACCAATGAGGCAGCGGGTTTGCGGCAGTGACGGTGTTGTCTGGCAAATGCCGTCAAAAAGCCAAACCTTCAGAATAACGGCAACAAAACAGTCGAAAAGAAGTGGTACGCGATATAATCACCTAGCACAGATGACAGACAGAACCGGAGAAAACGAAAAGATGAACAAGCAGCAACCAAGCCGTACTCAACATGGCGAGTTCATAAAGGTCAGAGCCTGACGCTGCTCGAAAAACTGGACGCATGATGTGACAGACAGACCGCCATGTGTGAGAAGCTGCACAGACTCACCAGAACTCAGGAACAGCATCCAGACACGCTTTGAGTGAAAATAGCACAGAAGATAGCGCTCAGGACAGGATGCCGAACGGCGCAACAGAGCGTAAGGAGAAAATGTCACATAAGGCGCTCTTCGCTTCCTCGCTCACTGACTCGCACGCTCGGTCGTTCGACTGCGGCGAGCGGTGTCAGCTCACTCAAAAGCGGTAGCGGTTATCCAGAATCCGGGGGATAAAGTCGGAAGAACATGTGAAGAGGCCAAAAGCAAAGCACCGGAGGAAGCCAGCGCCGCAGGCGTTTTCCATAGGCTCCGCCCCCTGACGAGAGCATCCACAAAAATCGACGCTCAAACCAGAGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGTGTTTCCTGGGAACTCCCTCGTTAACTCTCTGTTCCGACCCTTGCCGCTTACCGGATGCCGCAAATACTTCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTGCAAGCTCACGCTGTAGGTATCTCGGTTCGGTGTGGGTCGTTCGCTCAAGCTGGGCTGTGTGCACGAACCTGTCTCTTATACATCTCCAGAGCCCACGAGACCAG
-+
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
-@adea5f5d-ea3a-44ec-be6d-a8ed4623bcef
-CGTGCACACAGCCCAGCTTGGAGCGAACGACCTACACCGAACCGAGATACCTACAGCGTAGGCTGTGAAAGCGCCACGTTCCCGAAGGGAGAAAGGCGGACAGATCGGTAAGCGGCAGCAAGAAGTCGGAACAGGAGAGCGCACGAGGGAGCTTCCCGGGAAGCCTGGTATCTTTATAGTCCTGTCGGGTTTAGCCACCTCTGGCTTGAGCGTCGATTTTGTGATGCTCGTCAGGGGGGAGCAGGCCTATGGAAAAACGCCTGCGGCGCTGGCTTCACCGGTGCTTTGCTTTTTGCTCACATGTTCTTTCCGACTTTATCCCCCGATTCTGTGGATAACCGTATTACCGCTTTTGAGTGAGCTGACACCGCTCGCCGCAGTCGAACGACCGAGGCGTAGCAGGTCAGTGAAGCGAAAAGCGGAAGAGCGCCTTATGTGACATTTTCCATACTTTACGCTCTGTTGTGCCGTTCAAGCATCCTGTCCTGAGCGTTATCTCTCTGTGCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTGCAGCTTCTCACACATGCAGCCTGTTCGTCAGCATCGGGTGCGTCCAGTTTTTCGAGCAGCGTCAGGCTCTGACTTTGCGAATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTTCAGTTTTCTCCGTTCTGTCTGTCATCCGTTGTGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCAGAATTTATTCTGCCGCTTTGGCTTTTGACGGGCATTTCTGTCAGACAACACTGTCACTGCCAAAAAACTGCCGTGCGGCTTTGTCGGTGAATTCGAGGCTTATGACAGGACAGGATGTGCAATTGTTATACCGCGCATACATGCACGCCACAATTGCCCTGAGTCGAGCACCCGACACCCATGTCAGATGCGGAGCCATGTTTTATGACAAAACGAAGTGGAAGTAATACGCGCAGGAGCAGGCTAATAGTCGCCCTGTTCGTCTGACGGCGAAGAAGACCAGGAAATCGAAGGAGCTGCTGAATGCGGCAAGACCGTTTCCAGTTTTACGGGCGGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCAGGTACTGAAGAAGTTATGAGACTGAGGCGTTACAGAAAAAACTCTTTATCGCGACGGCAAGCGTGTCGGGGACAGAGTATGCGGAGGTGCTGATCGCTATTACGGAGTATCACCGTGCCCTGTTATCAGACTTATGGCAGATTATTCCCGGAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAAACGATCTGGCGCATCTTCTGTTTCCGGGGTAAAACGCATCTCTTT
-+
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
-@f7175d5d-ccb5-4e45-81ca-9ab4be906e25
-CGGTAGCCACTTCGTTCAGTTACGTATTGCTGCGCGCGCATCTCTGTCGTCGGCAGCGTCAGATGTGTATAAGAGACAGGTTCATACCGTCTGTTTTCGACGATTTTACTCTCCGGGAAGCTAATCTGCCATAAGTCTGAATCGCAGAACACGGTGATGCTCCGTAATATGATCAGCACCTCCGCATACTCCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTCTGTAACGCCCCAGTCTCATAACTTCTTTCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTACCGAGAGCTGCCGCCGTAAAACCGGAAACGGTCTTGCCGCATTCAACCCAGCCCTTTTTCTGATTTCCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATAAGCCCGCCTGCGCGTATTACTTCCACTTCGTTTTGTCATGAAACATGGCTCCGTATCTGACATAGATTGTGGGGCAAAGAAAGCCGGAAATGGGGCAATTAATAGCGTGCATGTATGCGCCGGTATAACAATTGCACATCCTGTCCTGTCAGCAAGCTCGAATTACCGACAAGGCACGGCAGTTTTGGCAGTGACAGTGTTGTCTGACAGAAATGCCCGTCAAAAAGCCAAGCGGCAGAATAACGGCAGCAAAACAGTCAGCGAAACAGCGCTTTAATCACACAACGCAGATGACAGACAGAACGGAGAAAACGAAAAGATGAACAAGCAGCAGCAAGCCCGTACTCAACATGGCGGGTTCATAAAAGTCAGAGCCTGACGCTGCTCAAACTGGACGCACCCGATGCTGACGAACAGGCTGCCATGTGCTGAGAAGCTGCACGAACTCGCAGAAGAACTCCCAGAACAGCATCCAGACACGCTTTGAAGTAGAAAATAGCACAGAGAGATAACGCTCAGGACAGGATGCCGAACGGCGCAGCAGAGCGTAAGGAGAAAATGTCACATAAGGCGCTCTTCCCGCTTCCTCGCTCACTGACTCGCTACGCTCCGGTCGTTCGACTGCGGCGAGCGGTGTCGCTCTCAAAAGTAATACGGTTATCCACAGAATCAGGGGATAAAGTCGGAAAGAACATGTGAGCAAAAGCAAAGCACCAGCGAAGCCAGCGCCGCGGGCGTTTTCCATATAGGCTCCGCCTGACGAGCATCACAAAAATCGACGCTCAAGCCAGGTATGGCGGAAACCGACAGAAAGCTATAAAGATACCAGATTGTTTCCCTGGAAGCTCCCTCGTGCGCTCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCGCCTTTCTCCTTCGGGAAGCGTGGCGCTTTCTCGCTAGCTCACGCTGTGGGTATCTCGGTTCGGTGTAAGTCGTTCGCTCCAAGCTAGACTGGCTGTGTGCACA
-+
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
-@337541c2-11a7-479e-964e-f5f6709c373e
-CGATGTGCTTCGTTCAGTTACGTATTGCTGCGCGCGCACCTCTCTGTCGTCGGCAGCGTCAGATGTATAAGAGACAGGAACGACCTACACCGAACAAAGATACCTACAGCGTATGAAGGCTATGAGAAAGCGCCACGCTTCCCGAAGGGGAGAAAGGCGGACAGGTATCCGGTAAGCGGCAGAGTCGGAACAGGAGAGCGCACGAGGGAGCTTCAGGAAACACCTGGTATCATAGTCCTGTCCCGGGTTTCGCCACCTCTGGCGGGCGTCGATTTTGTGATGCTCTCAGGGAGCGGAACCTGTAAAACGCCTGCGGCGCTGGCTTCCTCCGTGCTTTGCTTTTGCTCATGTTCTTTCCGACTTTATCCCCCGATTCGGATAACCGCTATTACCGCTTTTGAGTGAGCTGACACCGCTCGCCACAGTCGAACGACCGAGCGTAGCGAGTCAGTGAGCGAGCGGAAGAGCGCCTTATGTGACATTTTCTCCTTACGCTCTGTTGTGCCGCGTTGGCATCCTGTCCTGACGTTATCTCTCTGTGCTATTACTGCTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCCTGCGAGTTCGATGCAGCTTCTCACATGGCAGCCTGTTCGTCAGCATCAGGTGCGTCCAGTTTTCGAGCAGCGTCAGGCTGCCATGTGTGAAAACTGCACGAACTCGCAAGAAGAACTCCAGAGACAGCATCCAGACACGCTTTGAAGTAGAAAATAGCACAGAAGATAACGCTCAGGACAGGATGCCGAACGGCTAGCAGAGCGTAAGGAGAAAATGTCATAAGGCGCTCTTCCGCTTCCTCGCTCACTGACTCGCGCTCGGTCGTTCGACGCTGCGGCGAGCGGTGTCAACTCACTAAAAGCGGTAATACGGTTATCCACAGAATCGGGGATAAAGTCGGAAGAACATGTGAGCAAAAAGCAAA
-+
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
-@69d9e11f-e5b0-4f43-8830-b603688dda4b
-TGATATTGCCTGGATTCAGTTACGTATTGCTGCGCGCGCACTCTCTGTCGTCCGGCAGCGTCAGATGTGTATAAAGAGACAGACATAAGACTGGGAAGAGACAAAGGAATCTCAAAAACCTACAGCAATGCAATTTAACATGGATGATTTTCTTTTTCAGTTGAAAATGGCTGGGAGGTGGGATAAATGAAACCGAGAAAATAAATGATTATAAAAGTCATTTTCGTTGAGGGAGTGATGATGATTTTTCACTTCCTTTGCAATCTACTGCCCAAAAATAGAAGGAATTAATGATGTTTATGTTGAAAAAATAAATGGAAAGACAAAACTAAAACAAACCCTTAGAGCATTTAAAAGCATAGAGTCTTTTAATGAGAAAAGAAAGTATATTCTTAATCATCGATGCCGACGAATCGTTTTCCTGACACGGAAAGATCGATAATTTCAACATTAAATGAGCTTAACATTTCATCCGCCAAGCTCGCATAATGAAATAGCCATTAACGACACAAAAATATCTTTCTTTATCATGCCAAAAGTAAGAATAGCGCAATAGAAGATCTAATCATTGCTCACGCGTGTAAGAAGAGGTGTTTAGATATATAGACGATCTATTCAATAAAATAAAAGAACAAGAATCTATTATTACATCCTTAGATCCTGATTACGCTTACCCAAATAATGAAAAGAAAGCAAAAAAAAGAAAGTTCAAGTTTACCTTAGTTGTAATAAGGAATCAGATTCTAGAATGAGCACTATCAATGAAGAACAAAACCATTGATACTGACGATGACTGCTCAGTGAATAAAATTTATATCAAAAATATGAAACAACTCACCTACAAAATCATAGCGCAATGACTAAAGACAATTATAAAATTTAACATAATGCTGTAATTTGTACGCACACCGCTGAAACACGCACGCTGAACGCGATTCTGACGCGCACGAACACCGCAAAAGAGATGTTTTTACCGAGGAAAACAGGAAGGATGCGTCGGGATAATCGTTTTCAGCTCGCTGCATAGCTATGCATGAAAGCGAATGGTGATCACTTTGGGAGCGCGTGTGTTCATACCGTCTGTTTTCCTTAGTTTTTCTCCGGGAAGCTAATCTGCCATAAGTCTGGATAACAGGGCACGGTGATACTCCGTAATAGCGATCAGCACCTCCGCATACTCCTGTCCCCAACACGCTTGCCGTCGATAAAGTTTTTCTGTAACGCCCCAACCTCATAACTTCTTTCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTACCGAGAGCTGCCGCCCGTAAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCTTTTTTCGTTCCTGATTTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATATACCTGCGCCGTATTACTTCCACTTCGTTTGTCATAAAACATGGCTCCGCATCTGACATGGGTGTCGGGGCAAAGCCCTGACCAGGGCAATTGTAATAGCGTGCATGTATGCGCGGTATAACAATTGCATCGTCCTGTCAGCAAGCTCGAATTACCGACAAAGGCACGGCAGTTTTTGGCAGTGACAGTGTTGTCCTACGGCAAATGCCGTCAAAAAGCCAAGCGGCAGAATAACGGCAACAAAACAGTCGAAAAAGAGGTACGCGATATAATCACACAACGCAGATGACAGACAGAACGGAGAAAACGAAGAGATGAACAAGCAGCAACATGGCTCCATTACTCAACATGGCGGGATTCATAAAAAGTCAAACCTGACGCTGCTCGAAAAACTGGACGCACCCGATGCTGACGAACAGGCTGCCATGTGTGGGCTACACGAACGCTCGCAGAAGAACTCAGAACAACATCAGACACGCTTTGAAGTAGAAAATAGCACAGAGAGATAACGCTCAGGACAGGATGCCGAACGGCAACAGAGCGTAAGAATGTCATAAGGCGCTCTTCCGCTTCCTCGCTCACTGACTCGCTACGCTCGGTCGTTCGACTGCGGCGAGCGGTGTCCTTCACTCAGAAGCGATACGGTTATCCACAGAATCGGGGGATAAAGTCCGGAAAGAACATGGAGCAAAAGCAAAGCACCGGAGAAGCCAGCGCCGCAGGCGACGTTTTCCATAGGCTCCCGCCCCGACGAGCATCACAAAAATCGACGCTCGAAAGCCAGGGTGGCGAAACCCGCGACAGGACTATAAAGATACCGAAAGGTGTTTCCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCACGACCCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCCTTCGGGAAGCGTGGCGCGCTTTCTCATAGCTCACGCTAGCTAGTATCTCGGTTCGGTGTAAGGTCGGAACAGGAGAGCGCACGAGGAGCTTCCAGAAACACCGGTATCTTTATGAATCCTCGGGTTTCAAGCGAGCGTCTTTGTGATGCTCGTCAGGGCAGGTATGGAAGCGCTGCCCTGCGGCACTGGCTTCCTCCGGTGCTTTGCTTTGCTCACATGTTCTTTCCGACTTTATCCCCGATTCTGTGGATAACCGTATTACCGCTTTTGAGTGAGCTGACACCGCTCGCCGCAGTCGAACGACCGAGCGTAGCGAGTCAGTGGTACCAGGAAGCACCATATGTGACTTCTCCTTACGCTCTGTTGTGCCGTTCAGCATCTGTGGGCGTTATCTCTCCCTAATGCTATACACATCTGACGCTGCCGACGACAGAG
-+
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
-@1b328dea-2357-4033-a994-5bacc4524d2e
-CGCATCGGTGTTTGTACTTCGTTCAGTTTTCGCCTTTGCTGCGCGCGCACTACTCTCTGGTCTCGTGGGCTCAGGATGTAGCTATAGAGACAGATCCCCGACACACTTGCAAATCGGTGAGTTTTCTGCGCCCAGTCCTCAACTTCTTTTTCAGTACCAGTCAATGATCAATTAGGTTAACTTTCTCTTACCGAGGCTGCGCGTAAAAACCAGAGCAGATCTCTTGCCGCGTTCAATGACCCTTTTCAGTTCCTATGGTCTTCATGCAAATCGGACGAACAGGGCGACTGATAGCCCGCCACGCGCGTATTACTTCACTTCATTTTGTCATAAAACGCGGCTCCGTATCTGACATGGGTGTCAGACGAAATACAATAGAACAGTGTAATAGCGTGTGCTGCCAGAGTATAACAATTTGCACATCCATAATCATGTCAGCAGGCTCAGATTATGACAAAGGCGGCGGTTTTTGGCGGTAACCGGTGTTTATCTGACAGAAATGCCCGTCAAAGCAAACCTGGCAGAATAGCAACAGCAAAACAGTCAAAAGTGGTACGCGATATAATCCCTGGCACCGGATGACAGACAGAACGGAAAACGAAAGAGATGAACAACGACAGCAAAGCCCGTACTCAACATGGCGGGATTGCAAAAGTCAGGCCTGACGCTGCTCGAAAAACTGGATACCGATGCTGACGAACGGGCTGCCATGTGTGAGGAAGCTGCACGACTCGCAGAAGAACTCAGAACAGCATCAGACCGCTTTGAAGTGAAAATGGCACGGAGATAGCATCAGGACAGGGATGCCGAACGGCTACAACAGAACATGGAGGAAAATATCACATAAGGCGCTCTTCGCCTCGCTCTTGCCAGCTGCTTTACGCTCGGTCGTTCGACTGCGGCAGGCGGTGTCAGCTCACTCAAAAGCGGTAATACGGTTATCCCACAGAATCGGGGATAAAGTCGGAAAGGGCATGAGCAAAGAAATAGCAAAAGCCACCGGAAATGACGCCGCAGACGTTTTATAGGCTCCGCCCCCTGATAGGCATCCCACAAAAATCGACGCACTCAAGCCAGGGTGGCGAAACCCGACAGGACTATAAGATGGTGTTTCCCCTGGAGCTCCTCATGCGCTCTCCTGTTCCGACCCTGCCGCTTTGGATACCTGTCCGCCTTTCTCCCTTCCGGAAGCATGGCGCTTTCTCATAGCTCACGCCGTAGGTATCTCAGTTCGGTGTAAGGTCCTGTCTCTTATACATCTGACGCTGCCGACGACAGAGTGCGCGCGCATGTGCATATGTGCT
-+
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
-@c1c6d937-8f85-4b7e-923e-4ed33d20bb2a
-CCTACAGCGTGAGCTATGAGAAAGCGCCACGCTTCCCGAAGGGAGAGAAAGGCGGACAGGTATCCGGTAAAGCAGGGTCGGAACAGGAGAGCGCACGGAGGAGCTTCGGGAAACACCTGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTCTGGCTTGAGCGTCGATTTTGTGATGCTCGTCAGGAGACTGAGCCTATGGAAAAACGCCTGCGGCGCTGGCTTCCTCCGGTGCTGCTTTTTGCTCACATGTTCTTTCCGACTTTATCCCCGATTCTGGGGATAACCGTATTACGCTTTGGGTGAGGCTGACACCGCTCGCCGCAGTCGAACGACCGAGCGTAGCGAATCAGTGAGCGAGGAAGCGGAAGAGCGCCTTATGTGACATTTTCTCCTTACGCTCTGTTGTGCCGTTCGGCATCCTGTCCTGAGCGTTATCTCTCTGTGCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGGGTTCGTGCAGCTTCTCACACATGGCAGCCTGTTCGTCAGCATCAGATTGCGTCCAGTTTTTCGAGCAGCGTCAGTCTGGCTTTTTATGAATCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTCGTTTTCTCCGTTCTGTGTCATCTGCGTTGTGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTATGGCTTTGACGAGCATTTCTGTCAGACAACGCCGCCATCACTGCCAAAAAAACTGCCATTTTTGTTTGTCGGTAATTCGACTTGCTGACAGGACCAGGATGTGCAATTGTTATACCGCGCATACATACGCTATTACAATTGCCCTGGTCAGGGCTTTTGCCCCGACTACCCATGTCAGATACAGACGCGTTTTGCCGACAAAGCAGGTGATATCTGCGCAGGCGATATCAGTCGCCCTGTTCGTCTGACGGCAGAAGAAGACCAGGAAATCCAGAAAAGGGCTGCTGGTGCGACAAATTGTTTCCGGTTTTTTACGGGCAGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATGGGTACTGAAAAGTTATGAGACTGGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGAATTATGCGGAGGTGCTGATCCTTTATTACGGAGTATCACCGTGCCCTGTTATCAGACTTATGGCAGATTAGCTTCCCGGAGAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCCGGGGTAAAACATCTCTTT
-+
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
-@5843b9d5-3590-48a2-a03a-ab7ee4d7b794
-GTTGTACTTCGTTCAGGTTACGTGTGCTACGCACTCTCTGTCGTCGGCAGCGTCAGATATTATAAAGACAGCAGACGAACAGGGCGACTGATAGCCCATATGCATACTTCCGCTTTGTTTGTCACAAAACATGGCTCCATCTATCTGACATGGGTGTCAGGGCGAAGCACGATGGAACCAGTTGTAATAGCGTGCATGCCATGCGCGGTATAGCAATTGCACATCCTGTCCTGTCAACGGCTCGAGATTACCGACAAAGGCACGGCGGTTTTTGGCAGTGACGGTGTTGTCTGACTAAAAATGCCCGTCAAAAGCCAAGCGGCAGAATAACGGCAACAAAACAGTCGAAAAATTAGTACGCGATATAATCACACAACGCAGACAGCCAGACAGAACTGGAGAAAACGAAAGATGAACAAGCAACGGCAAGCCGTACTCCAACATGGCGGGATTCATAAAGAGGGTCAGAGCCTGACGCTGCTCGAAAAACTGGACACTCGCGATGCTGACGAACAGGCTGCCATGTGTGAGAAGCTGCACGAACTCGCAGAAGAACTCCAGAACAGCATCCAGACACGCTTTGAGTAGAAAATGGCACAGAGAGATAACGCTCGGAACAGGATGCCGAACGGCTAGCAGGCAATAAGGAGAAAAATGTCTACATAAGGCGCTCTTCCCTTTACTCGCTCACCTGACTCGCTACGCTCGGTCGTTTCGACTGCGGCGAGCGGTGTCAACTCACTCAAAAGCGCGGTAACTCACGGTTATCCACCAGAATCGGGGACAAGTCCGGAAAGAACATGTGAAACAAAAGCAAAGCGCCGGAGAAAGCCAGCGCCGTTTTCCATAGGCTCCGCCCCTGACGAAGCATCACAAAATCGACGCTCAAGCCAGAGGTGGCGAAACCCGACAGGACTATAAAGATACTGGTGTTCCTGGAAGCTCCTCGTGCGCTCTCCTGTTCCGACCCTGCCCGCTTCGGATACCTGTCCGCCTTTCTCCAGCTTCAGGAAGCGTGGCGCTTTCCGCAGCTCACGCTGTATGATTGCTGTCTCTTATACATCTCGAGCCATGAGACAGAGTGCGCGCGCAGCAATGCGTAGC
-+
-*$%)/..03,9C),%0>59=:56$@293,/*((/6.<A@><.,)1'-=B<B;592:+$&)+23-/%%0'$8217/0$%&,+,%,7<>;;=827.222%%#%%'%&$#'''('$$%'$$2=0.0**;<A@0**+-=>.0&#%&%8@174201$%&C/).%B=<:004*3).-,*),''%&$%#*&&-,*+,;<E9?0.)%$$&(<25+/:8*2%2(((,?@6B<00-'%449/*.2'&(#&',)#%%,-3))28<856),654?>>?'-;<?=;0(''->C.A*0=C==32:08,%%$),>?99A@=869EE?.9A@12$&%&%$&)76348+))'.6BDC<6,1(,%-,('$#($1+*3:<@?;5<90(=,+&+--0,++0,$%##&&&+-*-+0,*03;)/,JE?77604>7,,<7CC7>((7%,>:=7-3324$&,A8774=5:A00@)C<>//770&($%'.,-/015)(((-38><=:>--FGG=AA56*''((%#%00;65FH<5,+,,-8?@EDGD823,5554'.:9@@4;44--2:<>54=98+32B=A,FAB?A2--:9%%752:90<4---,(''0*)237-/(*)0115--6:88**/-6-:%)$(**39:21:8718=)-&&&%)'*(1%%'*+.,3&250A>::2:%%,((#$).;;@D@76,2++.,))/6ADI?7=+AE>@C9-8=;@00/A<6.+%-1EA@BB94<8>?32D@7;@4/3'(1/7('.5<=1)%&&+#''$%#$'+8/34<54461(8,-/5*A%+/$(($&$$$A8=24'6=:5'$$$&)((2CC9,)/'*%&1%8=?=>?%*')5414/09<45644')--./133271200/***+&'%&*('+.,<<==5=?=BCHBD69+C06)+86<6.-+-80;923=60B;79881%()-1'$#$$'&&&&*.)+/-)39;-242,5+7-6:2=9@HE?>254089<+(:;8&$'(*2897652/469;432288)2-1%##%)%$+/(.=65912,06890'&#$'4;;9)(((+%#$$&#$)(+++775<7;0++?67<.0(&)(&##&%&,09,3>EA2A,89309-9..+)'%$%&%
-@a30db388-a71f-402c-85b3-36772fce7f29
-GCCCCGACCAGAACAATTATATTAGCGATGCATCTTATGCGCAGTAACAATTGCGCATCCTGTCCTGTCAGCAATCTCGAATTACCGACAAAGGCACGCGGCGGTTTGGCGATGACAGTGTTCCGTCTGACAGAAAATGCCGATCAAAAAGCCAGACCGCTTCGAAGTAACGTCGGCAAAACGATCGAAAATGGTACGCGATATAATCACGCAACGCAGGCGTGAACAAGAACGGAAAACGAAAGATGAACAAACAACCATATAACAAAGCAAATGCTCAACATGTATGGATCATCAAAAGTCGAATTGAAGCCCGTATCAAGCAGGACGCGCCAATATATTGACGAACAGGCTTTGCCATGTGAAGCTACTACACAAACTCGCGCGAAGAGCTCAAATCTTCTCTCGGAACGGCGATCCGGTTGCCGAGCTTTGTGAAGTGAAATGGCGCGGAATGGCAGCTCGGGTCAGCAAGGATCTCCGAACAGCAACAGAGCGGCAGCAAGGAAGATGTCATAGGCGCTCTTCCACTTTCCTCGGCTGGCTCGCACTGACTCGCTGCGGCTCGGTCGTTCGACTGCGTGCGGCAATCGTCTCCTCGGCGGCGCTCGCTCAAAGTGATGTCTGATTATCCCGCGGAGATCAGGGAGATAAAGTCGGAAAGAACATGTGTGAGCAAAAACAGAGAAGCGGCTGCCGAGAGAGAAGCCCGGCGCCTCGAGCGTTTTCCATGGCATGAATCCGCCTGACGAGAGGGCATCTGGAATGCGATAGCATCTCGGAAGCCGGGTGACGAGACCGGGCGACAAAAGGACCTTTATAAAAAGATACCGGGTGTTCTCCCCTGTGGAAGCTCCTCGTGCCGCTCTCTATTTCCGACCCTGCCGCTTACCAGATAACGCAATCGCCTTTTTCTTCCTTCGGGAAGCGTGGCCCGGCTCTCATGGCTCGCGCTGT
-+
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
-@0065039f-a033-444a-afbe-fb5b048eadf4
-AAAGAATGTTTTACGGGAAAACAGGAAGGATGCGTCAGGATCGTTTTCAGCTCGCTGCATAGCTATGCATGAAAGCGAATGGTGATCACTTTGGGAGCTTACGGTGTTCATACCGTCTGTTTTCGACAGTTTTCTCCGGAAGCTAATCTGCCATAAGTCTGGATAACAGGAGCACGAGTGATACTCCCGTAATAGCGATCAACACCTCACCATCTCCTGTCCCCGACGCTTGCCGTCGATAAAGAGTTTTTTCTGTAGCAACACACAGTCTCATAACTTCTTTCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTACCGAGCTGCCGCCCGTAAAACCGAAACAGTCTTGCCGCATTCAGCAGCCCTTTTCTGATTTCCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATAGCCCGCCTGCGCGTATTACTTCCACTTCGTTTTGTCATAAAACATGGCTCCGTATCTGACATGGGTGTCGGGGCGAAAGCCCTGATGGGGGCGAATTGTAATAGCGTGCATGTATGCGCGGTATAACAATTGCACATCTGTCCTGTCAGCAAGCTCGAATTACCGACAGAGGCACGGCAGTTTTTGGCAGTGACAGTGTTGTCTGACAGAAATGCCCGTCAAAAAGCCAAGAAGCGGCAGAATAACGGCAGCAAAACAGTCGAAGAAGTGAGTACGCGATATAATCACACAACGCAGATGACAGACAGAACGGAAAACGAAAAAGATGAACAAGCAGCAGCAAGCCGTACTTTTTTAACATGGCGGGATTCATAAAAAGTCAGAGCCTGACGCTGCTCGAAAAACTGGACGCACCCGATGCTGACGAACAGGCTGCCATGTGTGAGAAGCTGCACAGACTCGCAGAAGAACTCCAGAACAGCATCCAGACACGCTTTGAAGTGAAAATAGCGCAGAGATAACGCTCAGGACAGGATGCCGAACGGCACAACAGAGCGTAAGGAGAAAATGTCACATAAGGCGCTCTTCCGCTTCCTCGCTCACTGACTCGCTACGCTCGGTCGTTCGACTGCGGCGAGCGGTGTCAACTCACTCAAAAAGCGGTAATACGGTTATCCACAGAATCGGGGGATAAAGTCGGAAAGAACATGTGAGCAAAAAGCAAAGCACCGGAGGAAGCCAGCGCCGCAGGCGTTTTCCTCAGGCTCCGCCCCCTGACGAGCATCCCCACAAAAATCGACGCTCAAGCCAGAGGTAGCGAAACCCGACAAGGACTATAAAGATACCGGGTGTTTCCCCCTGGAAGCTCCCTCATACGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGC
-+
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
-@a8d9c11a-715e-4da6-beb8-8a36644ac3fb
-GCAGGTATGCCAGTTCAGTTATTATTATGCGCGCGCACTCTCTGTCGTCAGCGGCGTCGGATGTAATATAAAGGACATCCTACAGCATGGAGGCTATAGAGCCACTCCACACACTTCCCAGAAGGGAGACGGACAGGTATCAGTAAACAGCAGAGGTCAGACAGAGGCACTTACGAGGGCCAGGAAACCTGGGTATCTTTTCTCAAATCCTGTCGGGTTTCGCCACCTCCAAGCGGGCGTCGATTTTGTGATGCTCGTCAGAGGCGGAGCCTATGGAAAAACGCCTGCGGCACTGTAGCCCTCCGGTGCTTTGCTTTTTTGCTCATATTCTTTCGACTTTATCCCCCAGTTCTGTGGATAACCGTATTACCGCTTTTGTTGGAGCTGACACCGCTCGCCGCAGTCAGACGACCGAGCGTAGCGGAGTCGGTGAGCAAGGAAGCGGAAGAGCGCCGTATGTGACATTTTCTCCTTTTGCTCTGTTGTACCGTTCAGCATCCTGTCCTGGGCGTTATCTCTCTGTGCTATTTTCGCTAAAGCTGATATCTGGATGCCTGGAGTTCTTCTGCGAGTTCATTACGGCTTCCACGCTAGCGGCTGTTCGTCAGCATCAGGTGCGTCAGTTTCGAGCAGCGTGGATCGGCTTTTATGAATCCGCCGTAGCGGGTGCGAGCGCAGCAGCGTTCGTACCACTTTCGTTTTCTGCAGATCTGTCATCTATCTCACCCGCCCTACATCTCAGGCCCCAGGATGGAGTGCGCGCAATGATGCAATAAT
-+
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
-@98c211dc-e814-413a-ad0c-7ff194308579
-CCGGGAAGCAGCAGGTCGGAACAGGAGAGCGCACGGGGAGCTTCCGGGAAACACCTGGTATCTTTATAGTCCTGTCGGGTTTCGCCAC
-+
-+*3:><98*$.(%(/,7$(%1/-444,+12..-2#&<6&9@CB*/%))175<=>?=-2:@<?ED.69<=67<=-(:+0>8?:=211$$
-@69d9e11f-e5b0-4f43-8830-b603688dda4b
-GGTCGGAACAGGAGAGCGCACGAGGAGCTTCCAGAAACACCGGTATCTTTATGAATCCTCGGGTTTCAAGCGAGCGTCTTTGTGATGCTCGTCAGGGCAGGTATGGAAGCGCTGCCCTGCGGCACTGGCTTCCTCCGGTGCTTTGCTTTGCTCACATGTTCTTTCCGACTTTATCCCCGATTCTGTGGATAACCGTATTACCGCTTTTGAGTGAGCTGACACCGCTCGCCGCAGTCGAACGACCGAGCGTAGCGAGTCAGTGGTACCAGGAAGCACCATATGTGACTTCTCCTTACGCTCTGTTGTGCCGTTCAGCATCTGTGGGCGTTATCTCTC
-+
-)3)@484@72300(*23.00--&4'&*%&'$)&('&'(332+**8;>>>01+%$$$%+*.-2466+&#$-/.+.+&&'$%(+487;<8>@50:0</4'$+*.3.%&%%'%'''*)-)+*6579&09.0%%5%5;.;..<4*+,>98EBD=D9@:3:<?B:;887.6=:468;;<=?65;9=BECA<@CHH>>=744757A@D;9?A@8002783?ABKB=EFECDJA=5)-85889618%,+-042+BD=B84''16+&56&''($'#)&+)#*'++.8?97330&&+1835//)'49?BBBCE5@E?F;;;/+.6432/'$#&&79<=<8=4*6%
-@673d0113-b870-4ab9-936d-43dbc5e80e78
-GTAGCACTTCGTTCAGTTACGTATTGCTGCCGCGTACCTCTCTGTCGTCAGCAGCGTCAGATAATATAAGAGACGGGATATGATCAACGCTTTGATAGAAGCAGCAAAAACCAATAATAATCAAATATTTACAACAACACACAGCCATGATGTAATATATTGCGATAAGCAGATTAGATGAAAAAGAAAAGATATATCTTACATAAGACTGGAAGGGAACAAGGGAATCTCAAAAACCTACCAAACGATGCAATTTAACATGGATGATTTTTCTTTTTCAGTTGAAAATGGCTGGGAGGTGAGATAAATGGAAACAGAAAAGTAAATGATTATAAAAAGTCATTTTCGTTGGGGGTGATGATGATTTTCCGCCTTTGCAATCTACTTGAAATAGAAGGAATTAATGATGTTTATGTTGAAAAAATAAATGGAAAGACAAACTAAAACAAACCCTTAGAGCATTTAAAAGCATAGAGGAGTCTTTTAATGAAAAAGAAATATATTCTTAATCATCAGTACCGACGAATCGTTTTTCTGACACGGAAAGATCGATAATTTCAACATTAAATGTTAACATTTCATCCTCAAGCTCGCATAATGAAATAGCCAAAGTAACGGAAGCACAAAATATCTTTCTTTATCATGCCAGGAAAAAACAAGAATGGCGCAATAGAAGATCTAATCATTGCTCACGCGTGTAAGAAAGAGGTGTTTAGATATATAAACGATCCATTCAATAAAATAAAAAGAATAAGAATCTATTAATACATCCTTAGATCCTGATTACGCTTACCCAAATAATGAAAAGAAAGCAAAAATTCAAGTTTACCTTAGTTGTAATAAGAATCAGATTCTAGAATAGGCATATCAATGAAGAACAAAACCAACGATGAGTACTGACGATATTTTGCTTCCAGTGAGATAAAAATTTATATCAAAAATATGAAACAACTCCACCTACAAAATCATAGCGCAATGACTAAAGACAATTATAAAATTTAACATAATGCTGTAATTGTACGCACCGCTGAAACGCGCTGAACGCGATTCACAGTACAGACACCGCAAAAGAGAGATGTTTACGGGAAAACAGGAAGGATGCGTCAGGATCGTTTTCAGCTCGCTGCATAGCTATGCATGAAAGCGAATGGTGATCACTTTGGGAGCTTACGGTGTTCATACCGTCTGTTTTCGACGGTTTCTCTCCGGGAAGCTAATCTGCCATAAGTCTGGATAACAGGGCACGGTGATACTCCGTAATAGCGATCAGCACCTCCATACTCCCTGTCCCGACACGCTTGCCGTCGATAGAGTTTTTTCTGTAACGCCCCCAGTCTCATAACTTCTTTCAGTACCGATCATCAGTCAGTGAGTTAACTTTCTTGAGAGCTGCCGCCGTAAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCAGCCCTTTTCTGATTTCCTGGTCTTCTTCTGCCGTCAGACGGACAGGGCGACTGATAACCCGCCTGCGCGTATTACTTCCACTTCGTTTTGTCATAAAACATGGCTCCGTATCTGACATGGGTGTCAGGGCAAAACCCTGACCAGAACGAATTAGCAATAGCGTGCATGTATGCGCGGTATAACAATTGCACATCATCCTGTCAGCAAGCTCGAGATACCGACAAAGGCACGGCAGTTTTTGGCAGTGACAGTGTTGTCTGACAGAAATGCCCGTCAAAAAGCCAAGCGGCAGACAACGACAAAACAGTCGAAAAGTGGTACGCGATATAATCACACAACACGCAGATGACATTGAACGGAGAAAACGAAAAAGATAAGGCAAGCAGCAGCAAGCCGTACTCAACATGGCGGGATTCATAAAAAGTCAGAACCTGACGCTGCTCGAAAAACTGGACGCACCCGATGCTGACGAACAGGCTGCCATGTGTGTGAGAAGCTGCACAACTCGCAGAAGAACTCCAGAACAGCATCCAGACGCAACGCGATGAAAAATAGCCTGGAAGGAATAACAACTCTCAGGACCTGCCAGATACCGAACAGCTGTAAGAGCATGGAAAATGTCACATAAGGCGCTCTTCACTTCCTCGCTCCTGACTCGCTACGCTCGGTCGAACCGACTGCGGCGAGCGGTGTCAGCTCACTCAGAAGCAGTAATGCGGGACATCCACAGAATCAGGGATAAAGTCGGAAGAACATGTAGACAAAAGCAAAGCACCCGGAGAAGCCAGCGCCGCGACGTTTTCATAGGCTCCGCCCCCTGACGAGCATCACAAAAATCAGCGCTCAAGCTAGGTGGCGAAACCCGACAGGATATAAAGATACCAGACGTTTCCCCACAAATTTGGCGTCCTCGTGCGCTCTCCTGTTCCGCCTTTCGGTTTACGGTGTCATTCCTTTATGGCGCGTTTATCCTGGTCCACGCCTGACACTCACTACGCGCGCGTGTCTCGTGGAGCTCGGAGATGTGTATAAGAGACAGACATAAACCAGTCTGTATGCTGCAACACTCATTTTTGTCCATTCAGCGAGCGCAGACGTTCATTGGCTATTTTCTGATGGGTTAGTTTCCACTTTTTCTTAAGCGGTTATCTCTACCAAGAACCTCATCAAACATGGCTTTGTGAATGATTTTAGGTCTTTTTCGGCACCGCCAACATATACGATTTCTTTCATTAGCACACCTCATACTTGTGTCGTCGATTAATAGCGTTCATACGCATACCTCTGTAGGTTGTAGTTGTCACTGTATTAAAAACAGGCAGATTTCAATTATTATACGGGTAATGAGATAATTGGAAGCTTGATTATATAAATTTTTGTATGTCAGCGAGCTGATCGCTTGCTTTTGAACGATTGGTGCGATGCATTTATCGTTTCTGCCAAATCTCGGTCATTTTTCTTGACGCGGGATTAAGTCAGGCTTAGTCTGGGGATGAAAAAAAACCGCCTGGGGAGGCGGTTTTTCAAGGTTCAATGAGTTGGGAACTCGTTGAACCAGGTATAACACACAGGCCGCGATACAAAACTTGTCTTTCAGTTTAGCCGTAGTCAGGCTGCTACTTCGAACTCTTGTGTAGTAAGTTTCTGCAATCTCACTCAAGTGAATCTGGCGCGTTACCAGTGGCTACCACCAATGTGGCGTGATGTTAATCATTACCACTCGGATTAGATCAAGAAGAAGATAGTTATGCCAGTGTGGCACCATTTTTGACAGCATTTTTATGTATTTGCATATA
-+
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
-@d9e35e64-b3d9-42fb-92d7-0c1b24b1450e
-CTTTATAGCCCTGTCGGGTTCCCTTTCTGGCTTGAGCGTCGATTTTGTGATGCTCGTCAGGGGGCCGGAACCTATGGAAAACGCCTGCGGCACTGGCTTCCTCCGGTGCTTAGCACGCCATGTTCTTTCCGGCTTTATCCCCCGATTCTGTGGTTAACCGTATTACCGCTTTTGAGTGAGCTGACACCGCTCGCTGCGGTCGAACGACCGAGCGTAGCGAGTCCAGTGAGCGAGGAAGCGGAAGAAGCGCCTTATGTGACATTTTCTCCCTTACGCTCTGTTGTGCCGTTCGGCATCCTGTCCTGAGCGTTATCTCTCTGCAGCATATTTTCTACTTCAAAGGCGTATCCCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTTGCGGCTTCTCACATGGCAGCCTGTTCGTCAGCATCGGGTGCGTCCAGTTTTCGAGCAGCGTCAGGCTCTGACTTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCCATCTGCGTTTATTTGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTGACGGAGCATTTCTGTCCGAATAACACTGTCACCATGCCCAAACTGCCGTGCGAACCTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATATTTGGAGGTGGTATACCGCGCATACATGCACGCTATTACAATTGCCCTGGTCAAGGCGCTTTGCCCCGACACCCATGTCAGATGCAGACCATGTTTGGCGACAAAACAGAGTGGAAGTAATACGCGCAGGCGGGCTATCGAATCGCCTGTTCGTCTGACGGCAGAAGAAGACCAGGGGAAATCAGAAAAGGGCTGCTGAATGCAGCAAGACCCGTTTCCGGTTTTACAGGCAGCAGCTCTCGGTAAGAAAGTTAACTACTGACTGATGATCGGGTACTGAAAGAAGTTATGAGACTGGGGGCGTTACAGAAAAAGCTCTTTATCGACGGCAAGCTGATGTCGGGGACAGGAATTATGCGGGTGCTGATCGCTATTCCGGGTATCCACCCACGTGCCCTGTTATCCAGACTTATGGCAGATTAAGCTTCGGAGAAAACTGTCGAGAAAACAGACAGGTATGATTGCCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATGGCTATTGCAGCGAGGCCTGAAAACAGTCTGGCTGTCTTCCCTGTTTTCGGGGGTTAAAGCATCTCTTT
-+
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
-@c37e7a68-8a79-4c37-a65b-0e8e4de71c06
-TTATAGTCCTGTCGGGTTTCGCCACCTCTGGCGAGGCGTCGATTTTGTGATGCTCGTCAAGGCGGAGCCATGGAAAAACGCCTGCGGCGCTGAAACTTTCCTGGTGCTTTGCTTTTTGCTCATGTTCTTTCCGACTTTATCCCCCGATTCTGTGGATAACCGTATTACCGCTTTTTAATTGTGACACCGCTCGCCGCAGTCAGACGACCAGGCGTACGAGTCAGTGAGCGAGGGAAGCGGAAGGCGCCATATGTGACATTTTCTCCTTACGCTCTGTTGTGCCGTTCGGCATCCTGTGACGTTATCTCTCTGTGCTATTTTCTACTTCGGCGTGTCTGGATGCTGTTCTGGGTTCTTTCTGCGAGTTCGGTGCAGCTTCTCACACCATAGCAGCCTGTTCGTCAGCATCAGGTGCGTCAGTTCCCGAGCAGCGTCAGGCTCTGACTTTTATGAATCCGCCATGTTGAGCACGGCTTGCTGTAGCGATTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACCACTTTCGACCTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTGACGACATTTCTATCCAGACAACACTGTCACTGCCAAAAAACTGCCGTGCCTTTGTCGGTAATTCGAGGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCATACATACGCTGGCCACAATTGCCCTGGTCAAGGAGCTTTGCCCCGACACCCATGTCAGATACCTGGAGCCATGTTTTATGACAAAACGAGTGGAAGTAATAATACGCGCGGGCGGGCTATCAGTCGCCCTGTTCGTCTGACAGCAGAAGAGACCGGAAATCAGAAAGGGCTGCTGAATGCGGCAAGACCGTTTCCGGTTTTACGGGCAGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCGGGTACTGAAAGAAGTTATGAGACTGGGGGCGTTACAGAAAAAATAACATCGACGGCAAGCGTGTCGGGGACAGAAATTATGCGGAGGTGCTGATCCTTTATTACGGAATTATCACCGTCGCCCTGTTATCCAGACTTATGGCAGATTAGCTTCCCGGAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTTCAGGGTAAAACATCTCTTT
-+
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
-@8e4e6ff4-59d7-450a-baf3-60b205e449d0
-GTTGTACTTCGTTCAGTTACGTATTGCTGCGCGCGCACTCTCTGTCGTCAGCGGCGTCAGATGTGTATAAGAGACAGCCGTAATAGCGATCAGCACCTCCGCATACTCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTCTGTAACGCCCCCAGTCTCATAACTTCTTTCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTACCGAGAGCTGCCGCCGCTAAAAAACCGAAACGGTCTTGCCGCATTCAGCAGCCCTTTTTCTGATTCCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATAGCCCGCCTGCGCGTATTACGCCCACTTCGTTTTGTCATAAAACATGGCTCCGTATCGACATGGGTGTCGGGGGCAAAGCCCTGACATCAGAGCGGTGTAATAGCGTGCATGTATGCGCGGTATAGCAATTGCACATCCTGTCCTGTCAGCAAGCTCGAATTACCGACAAAGGCACGGCAGTTTTTGGCAGTGGCAGTGTTGTCTGACAGAAATGCCCGTCAAAAAGCCAAACTGGCAGAACTAACGGCAACAAAACAGTCGAAAAGTGGTACGCGATATAATCACACAACACAGATGACAGACAGAACGGAGAAAACGAAAAGATGAACAAGCAGCGGCAAAATAATACTCAACATGGCAGGATTCATAAAAGTCAGAGCCTGACGCTGCTCGAAAAACTGGACGCACCCGATGCTGACGAACAGGTTGCCATGTGTGAAGCTACACGAACTCGCAGAAGAACTCAGAACAGCATCCAGACACACGCTTTGAAGTAGAAAATAGCACAGAGGAGATAACGCTCAGGACAGGATGCCGAACGGCACAACGGAAACAATAAGGAGAAAATGTCACATAGGCGCTCTTCCGCTTCCTCGCTCACTGACTCGCTACGCTCGGTCGTTCGACTGCGGCGAGCGGTGTCAACTCACTCAAAAGCGGTAATACGGTTCATCCACAGAATCGGGGATAAAGTCGGAAAGAACATGTGAGCAAAAACAAACACCGGAGGAAGCCAGCGCCGCAGCGTTTTCCATAGGCTCCGCCCCTGACGAGCATCACAAAAATCGACGCTCAAGAGCAATACGTAAC
-+
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
-@28313655-4a2d-420e-b320-6e2b25d9d019
-AAAGAGATGTTTGCAGGAAAACAGGAAGGATGCGTCAGGATCGTTTTCAGCTCGCTGCTTAGCTATGCATGAAAGCGAATGGTGATCACTTTGGGAGCTTGCATTGTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCGGGAGGCTAATCTGCCATAAGTCTGGATAACAGGGCACGGTGATACTCGTAATAGCGATCCAGCACCTCGCATACTCCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTCTGCTTAACGCCCCCAGTCTCATAACTTCTTTCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTACCGAGCTGCCGCCCGTAAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCCTTTTTCTGATTTCCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATAGCCCCGCCTGCGCGTATTACTTCCACTTCGTTTTGTCATAAAACATGGCTCCGTACCTGACATGGGTGTCGGGGCAAAGCCCTGACCAGGGCAATTAGCAATAGCGATGCATGTATGCGCGGTATAACAAATTTACCACATCCTGTCCTGTCAGCAAGCTCGAATTACCGACAAAGGCACGGCAGTTTTAGCAGTGACAGTATCTGACAGAATGCCGTCAAAAAGCCAAGCGGCAGAATAACGGCAACAAAACAGTCGAAAAAGAAGTGGTACGCGATATAATCTACAACGCAGATGACAAAGACAGAACGGAAGAAAACGAAAAGATGAACAAGCAGCAGCAAGCCGTACTCAACATGGCGGGATTCATAAAAAGTCAGAGCCTGACGCTGCTCGAAAAACTGGACGCACCCGATGCTGACGAACAGGCTGCCATGTGTGAAAAGCTGCACGAACTCGCAGAAGAACTCAGAACAGCATCCAGACACGCTTTGAAGTAGAAAATAGCACAGAGAGATAACGCTCAGGACAGGATGCCGAACGGCTTCAACAGAGCGTAAGGAGAAAAATGTCACATAAGGCGCTCTTCCGCTTCCTCGCTCACTGACTCGCTACGCTCGGTCGTTCGACTGCGGCGAGCGGTGTCGAACTCACTCAAAGCGGTAATACGGTTATCCACAGAATCGGGGGATAAAGTCCGGAAAGAACATGTGAGCAAAAGCAAAGCACCGGAGGAAGCCAGCGCCGCAGGCGTTTTTCCATAGGCTCCGCCCCCTGACGAGC
-+
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
-@1dde4b69-f80c-43f1-a3f3-b5f3c8e9f954
-AAAGAGATGTTTTACCCCGGAAAACAGGGAGAGGATGCGTCAGGATCGTTTTCAGCTCCGCTGCATAGCTATGCATGAAAGCGAATAGGTGATCACTTTGGGAGCTTACGGTGTTCATACCGTCTGTTTCGACAGTTTTCTCTCGGGAAGCTAATCTGCCATAAGTCTGGATAACGGAGCACGGTGATACTCCGTAATAGCGATCAGCACCTCCGCGCGTACTCCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTCTGTAACGCCCCCAGTCTCATAACTTCTTTCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTACCGAGAGCTGCCGCGCCCGTAAAAAACCGGAAACGGTCTTGCCACATTCAGCAGCCCTTTTTCTGATTTCCTGGTCTTCTTCTGCCAGGTAAGCGAACAGGAGGGCGACTGATAGCCCGCCTGCGCGTATTACTTCCCACTTCGTTTTGTCGCCGCTGCGCGGCTCCGTATCTGACATGGGTGTCGAGCAAGGCTGACGGGCAGTGTAATAGCATTACGCCATGCGCGGTATGGCAATTGCACATCCTGTCCTGTCAACAAAGCTCAGATTACCGACAAAGGCACGGCGGTTTTTGGCAGTGACAGTGTTGTCGACCCAGAAATGCCAATCAAAAATGACGGCAGGAATAACGGCTTAGCAAAACAGTCGAAAAGTGGTACGCGATATAATCACACAACGCAGATGACCAGACAGAACGGAAAAACGAAAAGATGAACGTCGCAAGCAGCAGCAAGCCACGTACTCAACATGGCGGGATTCATAAAAAGTCAAACCTGACGCTGCTCGAAAAACTGGACGCGCGATGCTGACAGACAGGCTGCCATGTGTGAGAAGCTGCACAGACTCGCAGAAGAACTCCAAGAACAGCAAGCATCAGACACACGGCTGGAGTAGAAAATGGCCACAGAATGCGCTCGCTCAGGACAGGATGCCGAACAGCGGCGCAACTGTAGAGCGTAAAGGAGAAAAATGTCACATGGGCGCTCTTCCGCTTCCTCGCTCACTGACTCGCGCTACGCTCGGTCGTTCGACTGCGGCAGGCAGTGTCAGCTCACTCAAAAGCGGTAATACGGTTATCCACAGAATCGGGGATAAAATTCGGAAAGAACATGTGAGCAAAAGAGAAACTAACGCAAGCACCGGAGGAAGCCAGCGCCGCAGGCGTTTTCCAT
-+
->.%)(+/(7=AD/''333,1'*8@.(/4-0$53=9878,*/)2::240;;:2%*+01(3/376C/>@?@A;5405>A:88C;**1($1=AB=9F>67:B,,6/3222;G>A?@B4;0033=9:A9;;;;11-)),57M<@=9/>(,3126>@=<8=:3%%$%#&,8@<?BAA;:9,2'003806FF@B0-13@8>AA9/25=2&48-68698+/)(#&$$$%:22,6;<=EJE>@=65357>@DEC>DCHA@B)1)?KNNF77,)++.2/-*//05779=@4411--?<>@B/-/;57A<909A51?;926+5573138@6.::A<BBAFC>7*4-;>@C?91AC@5C@GG:951;A45+.5>(1//&&%'*$>;@1,7$)%17822:KJ.>,B@OIH58@:<:=9:5=?%/'&&%*(.#%%()(15/30*&''-;97@BB71?HHC200=BD?HFD@B@66>?9>@7;>=CCMGEA6.*%$$&'()$&$,3=>,745.=D2GEBAB?=A<50.'%(*$&$%$$&%%&)('(&<45:9,&&(#$)))%$$$$2?AC)04//%&*-/-1;?8CD<=AD@,,27-):$%;66+)@;;&&8DCA=?=EAFG05:A2/5)%.4=4>=>8@5-:@A;/*403&((((($$++''.1;8563(()5')-,'&)&''./(.%:=;&'/,0&&&*(@@CGG51<3501,@=4A44/0-01=>;:<;;9A39?E@BJ=2-<A=;1((1/7<?;@@C8;&*218:++1+%1?')'*%&)*&&594/+7782:+-+--(-*/.$)B71..9;5H+2>255-)*=?*((/?C-1'459>.-%3<<B<>=>CDFC;;CGA=))%:<:+>??<:3-/>56823EB?C;<?7=?CA11=1))&$%,''4348)))+.846=BA*>12'9;*,&.01,8.*;46/0%$"%#&%)(-&(/++2,<@:-.%+(+,)('$%$$$#013//&4=?4(9<=90;18%$+')-+.0,-&&$+0(/%*;77;::&8*/&39=92*68>2911*-82249C76'-&023&+.,'&*)&'))*78@6%44;4B863B7:4A?DB776<>9E152)+:*%3930'%$)+:-40<<@411>&.5')04B3757389C;@I:=92C',22,3%'&$$$$588BA0;73;:==A@:;FC3+&*$(+,)&'&(#$"%$-)27120-.+/,::A??1>?2&)))745AB>?@89
-@b95c096c-77a7-4419-b30d-6ad0d79d861e
-TGGAAAAACTTTGCCTGCGGCGCTGGCTTCCTCGTTGCTTTGCTTTTTGCTCACATGTTCTTTCAGGCTTTATCCCAAGATTCTGTGGATAACCGTATTACCGCTTTTGAATTGAGCTGACACCGCTCGCCGCAGTCCGAACGACCGAGCGTAGCAGTCAGTGAGCTGAGGAAGCGGAAGAGCGCCTTATGTGACATTTCTCCTTACGCTCTGTTGTGCCGTTCGGCATCCTGTCCCTGAGCGTTATCTGTGCCTATTTTCTCACTTCAAAGCGTGTGGATGCTGTTCTGGAGTTCTTCTGCGATTCGTGCAGCTTCTCACACATGGCGGCCTATTCGTCCAGCATCGGGTTGCGTCCAGTTCCGAGCAGCGTCAGGCTCTGACTTTTTATGAATCCCGCCATGTTTGGTGGCTTACTGCTGCTTGTTCATCTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTTGTGTGATTATATCGCGTACCACTTTCGACTGTTTGCTGCTGCATTATTCTGCCGCTTGGCTTTTGACGGGCAGTACAGCAGACAACACTGTCACAGCCAGAAAACTGCCGATGCCGCTGTCGGTAATTCAGGCGCCTTGCTGACAGGACAGGATGTTACGGTGTTCTCACCTTTGCCGTACGCTATTGATGCCTAGTCGAGCACTGCCCCGACACCATGTCAGATGCGAACCATGTTTTATCGTTGAAACGAAGTGGAGTAATACGCGCGGGCAGATCAGTCGCCCTGTTCGTCTGACGGCGAAGACCAGGAAATCAGAAAGGGCTGCTGAATGCGGCAAGACCGTTCCGGTTTTACGGGCAGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCAATTACTGAAAGAAGTTATGAGACTGGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGGACAGGGAGTATGCGGAGGTGCCGATGCTACATACGGAGAATATCACACCGTGCCACATTATCCAGACTTATGTAGTTAGCTTCCCGGAAAGCTGTCAGCGGTATGAACACCGTAAACTCCCAAAGTGATCCTGCCATTCGCTTTCATGCATGCTTATGCAGCGAGCTGAAAAGCGATCCTGACGCATCCTTCCTGTTTTCCCAGGGTAAAACATCTCTTT
-+
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
-@c5915a53-2ddf-4c79-a9bb-67ea7e683f5b
-GGTGCGCTGATTTCAGTTTATCTTGTTATCGGTGCTGCTTTTTTATCACATGTTCTTTCCGACTTTATCCCGATTCTGTGGATAACCGTATACACTTTTTGAGTGAGCTGACACCGCTCGCCGCAGTCAGACGACCGAGCGTAGCAGTCAGTGAGCGAGAGCAGGAAGAAACATATTATCTTGACATTTTCTCCTTACGCTCTATTTGTGCCGTTCGGCATCCTGTCCTGAGCGTTATCTCTCTGTGCTATTTTCTACTTCAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGATTCGTGCAGCTCACACATGGCAGCCTGTTCGTCATCAGGTGCGTCAGTTTTTCGGCGACAGCGTCAGGCTCTGACTTTTTACTAGATCCCGCCATATTTAAGTACGGCTTGCTGCTGCTTGTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTATCTGCGTTGTGATTGCCTCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCGGCTTTTTGACGGGCATTTCTGTCAGACAACACTGTCACTGCTAACTGCCGTGCGGTTTGTCGGTGAGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCGCATACATGCACGCTGTACAATTGCCCTGGTCAGGAGCTTTGCCCCGACACCCATGTCGGATACGGAGCCATGTTTTATGACAAACGAAGTGGAAGTAATACGCGCAGGCGGGCTATCCAGTCGCCCTGTTCGTCTGACGGCGAAGAAGACCAGGAAATCAGAAAAGGGCTGCTGGATGCAGCAGAACCGTTCCGGTTTTACGGGCGGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCGGGTACTGAAGAAAAGTTAGGAGACTGGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGAGTATGCGGGGTGCTGATCCTTTGTAAGATATCACTGTTTACCTGTTATCAGACTTATGGCAGATTAGCTTCCCGGAGAAAACTGTCCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGGTCACCTGGCTGCTTTCATGCATGGCCATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCTGTTTTCCCCGGGTAAAACATCTCTTTATGCAGTGTCTGCGTCAGAATCGCGTTCAGCGTTTCAGCGGTGCGTACAATTACAGCATTATGTTAAATTTTATAATTGTCTTTAGTCATTGCGCTATGATTTTGTAGGTGGAGTTGTTTCTATATTTTGATATAAATTCTTTTATCTCACTGACGCAGTCATCGTCAGTATCAATGGTTTTGTTCTTCGTCTGATATGCTATTCTAGAATCTGATTCCTTATTACAACTAAATTAAAGCTTGAACTTTTGCTTTCTTTTCATTATTTAGGTAAGCGTAATCAGGATCTAGGATGTAATAATGATTCTTGTTCTTTTATTTTATTGAATAGATCGTCTATATATCTAAACACCTCTTTCTTTGCGTGAGCAATGGTTAGATCTTCTATTGCGCCATTCTTGTTTTCCTGGCATGATAAAGAAAGATATTTTTGTACTTCCGTTAATGGCTATTTCATTATGCGAGCTTGGTGATGAAATGTTAAGCTCATTTAATGTTGAAATTATCGATCTTTCCGTGTCAGAAAACGGGATTCGTCGGCATCGATGATCAAGAATATACTTTCTTTCATTAAAAGCTGTCTCTTATACACATCTCCGAGCCCGAGACCAGAGAGTGCGCGCGCAGCCAGTACGTAAC
-+
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
-@740cc161-5d43-436f-a43a-a4f8eca5395a
-GTTGTAGCGTTCAGTTACGTATTGCTGCGCGCGCACTCTCTCTGGTCTCGTGGGCTCGGAGATGTGTATAAAGAAGCAGTCATCAGTCAGTGAGTTAACTTTTTCTTACCGAGAAGCTGCCGCCCGTAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCTTTTTCAGTTTCCTGGTCTTCTTCTGCCCCGTCAGACGAACAGGGCGACTGATATAACCCGCCTGCGCGTATTACTTCCACTTCGTTTTGTCATAAAAACATGGCTCCGTATCTGACTTAGGTGTCAGGCAAAGCCCACGATGGGGCAATTGTAATAGCGTGCATGTATGCGCGGTATAACAATTGCACATCCTGTCCTGTCAGCAAGCTCGAATTACCGACAAAGGCACGGCAGTTTTTGGCAGTGACAGTGTTGTCTGACAGAAATGCCGTCAAAAAGCCAAGCAGCTTAAGAATAGCAGCAGCAAACAGTCGAAAAGTGGTACGCGATATAATCACACAACACAGATGACAGACAGAACGGAAAACGAAAAGATGAACAAGCAGCAGCAAGCCGTACTCAACATGGCGGGATTCATAAAAAGTCAGAGCCTGACGCTGCTCGAAAAACTGGACGCACCCGATGCTGACGACAGGCTGCCTGTGTGAGAAGCTGCACGAACTCGCAGAAGAACTCCAGAACAGCATCCAGACACGCTTTGAAGTAGAAAATAGCACAGAGAGATAGCAACTCAGGACAGGATGCCGAACAGCACAAGCAAGAGCGTAAGGAGAAAATGTCACATAAGGCGCTCACTTCCACTTCCTCGCTCACTGACTCGCTACGCTCGGTCGTTCGACTGCGGCGAGCGGTGTCAGCTCACTCAAAAGCGGTATACCACGGTTATCCACAGAATCAGGGGATAAAGTCGGAAAGAACATGTGAAGACAAAAGCAAAGCCTGTCTCTTATACACATCTGACGCTGCCGACGACAGAGTGCGCGCAATGACCGTAAAC
-+
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
-@7eb86c25-f9b4-4bc4-bc7d-e27d49daaafe
-TTGCTCACATGTTCTTTCCGACTTTATCCCCGATTCTGTGGATAACCGTATTACCGCTTTTGAGTGAGCTGACACCGCTCGCCGCAGTCGAACGACCGAGCGTAGCGAGTCAGTGGGCGAGGGAAGCGGAAGAAGCACCTATGTGACATTTTCTCCTTACGCTCTGTTGTGCCGTTCGGCATCCTGTCCCTGAAACGTTATCTCTGTGCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTTACAGCTTCTCACACATGGCAGCCTGTTCGTCAGCATCGGGTGCGTCCAGTTTTCGAGCAGCGTCAGGCTCTGACTTTTTATGAATCCCGCCATGTTGGGTACGGCTTGCTGCGCAACGTTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTGACGGAGCATTTCTGTCGAATAACACTGTCACTGCCAAAAAACTGCCGTGCCGAAAAATTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCATACATGCGCTATTACAATTGCCCTGGTCGGGGCTTTGCCCCGCGTTTACCCATGTGTCAGATACGGAGCCATGTTTATGACAAAACGAAGTGGAAGTAATACGCGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACGGCGAAGAAGACCAAGGAAATCAGAGAAAAAGGGCTGCTGAATGCGGCAAGACCGTTTCCGGTTTTACGGGCGGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATTCGGGTACTGAAAGAAGTTATGAGACTGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCAGGGACAGGGAGTATGCGGAGGTGCTGATCGCTATTACGGAGTATCACCATGCCCTGTTATCAGACTTATGGCAGATTAAACCCGGAGAGAAAACTGTCGAAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCATCCTGTTTTCCCGGGGTAAAACATCTCTTT
-+
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
-@6ed19357-064a-4b92-a597-e6f459c4a8cc
-GCAATTGTTATACCGCGCATACATGCACGCTATTACAATTACACATCCTGTCCTGTCAGCAAGCTCGAATTACCGACAAGGCCTGGCAGTTTTTGGCAGTGACGGTGTTGTCTGACTAGAAAATGCAAACCAGGCGCGAAGTAACGGCAACAAGCTGATCGGCGCATGTTTGAACAGAACGGAAAAACGAAAGATGAACAAGCAGCGGCAAAGCCGGCGATCATAAAGTCAGAGCCCTTCAAACTGGACACTGTTAGCGGCGAACAACACCAGTGTGACTCGCGGAAAGGAACTCCGGGAGCCAGCGTCCGGAAAACGCCGGCACCTGAGTAGAAAGATGGCGCAGATCGGCAGCTCAGGACAGGATCACCGAACGGCACAACTGAAGCGTAAATGTCACATGGAAATCCTTTCCTCGCTCGCTGATACGCTCGGTCGTTCGACTACGGCGCGATAACTCACTCAAAGAAACGATGGCTCTGTTATCCACAGAATCGGGGGTTCGGAAAGA
-+
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
-@75e19ca0-46ae-43a5-b0b5-dee515129a2c
-AAAGAGATGTTTTACCGGAAAAACTGGGAAGGATGCGTCAGGATCGTTTCAATCGCTGCGTGGCTATGCATGAAAGCGAATGTGGTGGTCCTTTTGGAGACTTACGGTTGTTCATGCCGTCTGTTTCGACAGTTTTTCTCTCAGGAAGCTAATCTGCCCATGGGGTCTGGATAGCAGAGTTGCAGTTGATTACTCCGTAGTAGCGGTCAGCGCCTCCGCGTACTCGCAATGCAGCTACGCTTACCCGTCGATAAGAGTTTTCTGTAACGCCCCCAGTCCGCCTTGCTTTCAGTACCCGATCATCAGTCAGTGGAGTTACTTTCTTACCGAGCTGCCGCCCGTAAAAACCGAAACGGTCTGCCGCATTCAACAGCCTTACGATTCCCTGAATTAACCTTCTGCCGTCAGACGAACAGGGCGACTAATAGCCCGCCTGCGCGTAGCTACTTCCACTTCGTTTGTCCCATAAAACAGCTCCGTATCGGCGTGGGTGTGGGGCCAAAGCCTAATGGGGCAGTGTAATAGCGTGCGTAATATGCGGTATAACGATGCACATCCTATCCTGTCAGCAAGCTCAATTACAAAAGCAAAGGCACGGCGGTTTGGCGGTGACAGTGTTGTCTGACGAAATGCCGTCAAAGCGAAACGCAGAATAACGGCGGCAAAACGGTCGAAGAGTGGTGCGATATAATCGCACAACGCAGATGACAGACGGAACGGAGCTTGAAGATGAGACAACAACAACAAGCCGTACTCAACATGGCGGGATTCATAAAGTCAGAGCCTGACGCTGCTCGAAAAACTGGACCGCCAATGCTGACGAACAGGCTGCCATGTGGCGAAGCTGCACGAACTCGCAGAAACTCAGAGCAAGCATCAGGCACGCTTTGAAGTAGAAAATAGCACAGAAGAATAACGCTCAGGACAGGATGCGAACGGCTAGCAGAGCGTGGAGAAAAATGTCGTGGGGCGCCTCTTCCGCCCTCGCTCACTGACTCGCTACGCTCGGTCGTTCGACTGCTGACGAGCGGTGTCAGCGCTCAAAAGCGGTA
-+
-;*%)262869=?;/?>,1+/0/)++,1A:@(B88430.2--11;=9EF12%%)1&&2,,$+$*0/++*2&+65+&4:666*+))*'%(%%/%+,,%(&%&'(($/%*5;-792'%%+-47<B5/0,+0:,'8;9;8.+5&*&$-417/319:8;62BC>0(%&%41/%$(+($,100*8,.*($)%&,))-14?791-'$'%'*$(.*&)&%++.2:1310('&,%*)*)'*&&%%'5)'50)448<89--3/1'#6DFE>6,((..<@MOMI+(5'','&&%)#&*+,1+:1/998,,8>4.3(61.$.7%&%43,'$&''*((,,-.++..+,/5779;<DF51.;/(&+)8'&++0'5/3713+6$%*+%&%$%''&'/3'36630/,-(('&+68;=685075<;5./9--)10*3($)$&(%1559;@?@85483*1&&*-&&'(.0;@@;=C@@+%%>5$1333/'$')),;8=923$&"%($)$=*&&(,6$7:;1*-%'%&$&'&%+&&4)*14103*&8-6$%$$-.&&0.,'(.00)$%%'2+;<446,'026843310?/21?;2%(%'%$$%(&'<12%1./&'22/(,&*;(((+4;<=*$6@=AB84B4945%%5<78AD;6><=3-3+.,$('*6+6EE78I=AC$-B=:97B2722&'1)(.>44:./**::>?<5?%(%)&'*&85>EA>A94ABC585-2()$-))*''*1./7-%03,(:((:&'845+780985/B<==/C67;52-3;B:((<<6/87-,-)2,12/759>7==,%////(23%'&$$%))%'%&)15.-/.2.&-(35441&(()$%$''00//0-*-++*+-3'*&$+)*&&/31-.6468:-$.'*%,'.(&,,*(&'%0%%--/('+'+++-,1''+51)*)&&(102:630=B9B584230')$,%+,2&,%5*80550(%$(&%&('&*)-(%#$##$$$,%'%$'+/C<?<;%)//**.856=8<4;=@/.-))37.6.4:'((7(,'%'>/1:/&62.21458AB4)6;06.6
-@c293e042-18bb-414b-8014-9b996a71a683
-GACACCGCTCGCCGCGGTCAGACGACCGAGCGTAGCGAGTCAGTGAAGCGAGGGAAGCGGAAGAGCGCCTTATGTGACATTTCTCCTTACGCTCTGTTGTGCCGTTCGGCATCTGTCCCTGAGCGTTATCTCCTGTGCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGGTTCTTCTGCGAGTTCGTGCAGCTTCTCACACATGGCAGCCTGTTCGTCAGCATCGGGTGCGTCCAGTTTTCTCGAGCAGCGTCAGGCTCTGACTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACCACTTTTTCGACTGTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTGACGGGGGCATTTCTGTCAGACAACACTGTCACTGCCAAAAAACTGCCGTGCCATTTGTCGGTAATTCGAGCTTGCTGACAAGGACAGGATGTTACAATTGTTATACCATACCATACATGCACGCTATTACAATTGCCCTGGTCAGAGACTTTGCCCCGACACCCATGTCGAGATACAGACCATGTTTTATGACAAAACGGGGAGTGGAGTAATACGCGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACGGCAGAAGAAGACCAGGAAATCAGAAAAGGGCTGCTGAATGCGGCAAGACCGTTTCCGGTTTTACGGGCGGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCGGGTACTGAAGGGTATGAGACTGGGGGCGTTACGAGAAAAAACTCTTTATCGACGGCAAGCGATGTCGGGGGGACAAGGGAGTATGCGGAGGTGCTGATCGCCCTATTACGGGTATCACCATTGCCCTGTTATCCAGACTTATGGCAGATTAGCTTCCCGGAGAAAACTGTCGAGAAACAGACGGTATGAACACCGTAAACTCCCAAAGTGATCACCAATTCGCTTTCATGCATAGCTATGCAGCGAGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTCTCCGGGTAAAACATCTCTTT
-+
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
-@16d27977-1924-4acc-b4bc-18ffb166a119
-GTTGTACTTCGTTCGGTTACGTGTGCTGCGCGCGCACTCTCTGTCGTCGGCGGCGTCAGATGTGTATAAGAGACAGCCTTACGCTCTGTTGTGCCGTTCGGCATCTGTCCTGAGCGTTACCTCTCTGTGCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTGCAGCTACCATGGCAGCCTGTTCGTCAGCATCAGGTGCGTCCAGTTTTCGAGCAGCGTCAGGCTCCTGACTTTTTATGAATCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTTCGTTTCTCCGTTCTGTCTGTCATCTGCGTTAGGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTTGACGGGCATTTCTGTCAGACAACACTGTCACTGCCAAAAAACTGCCGTGCCTATTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCATACATGCACGCTATTAATTGCCCTGGTCGGGCTTTGCCCCGACACCCATGTCAGATGCAGACCATGTTTATGACAAAACGAAGTGGAAGTAATATACACGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACGGCAGAAGAAGACCGGGAAATCCAGAAAGGGCTGCTGAATGCGGCAAGACCGTTTCCGGTTTTTACGGGCGGCGGCTACTCGGTAAGAAAGTTAACTCACTGACTGATGATCGGGTGCTGAAAGAAGTTATGAGACTGGGGCGTTACAGAAAAAACTCTTTATCGATGGCAAGCGTGTCGGGGACAGGAGTATGCGGAGGTGCTGATCGCTATTACGGAGTATCACCGACACCTGTTGCATCCAGACTTATAGCGGTCTTCCCGGAGAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTTTCATGCATAGCCTATGCAGCGAGCTGAAAGCTCCTGACGCATCCTTCCTGTTTTCCCGGGGTAAAACATCTCTTTTGCGGTGTCTGCGTCAGGAATCGCGTTCAGCGCCGTTCCGGCGTTGCGTACAATTACAGCATTATGTTAAATTTTATAATTGTCTTTAGTCATTTGCCTTATGATTTTGTGGGTGGAGTTGTTTCATATTTTGAAATATAAATTCTTTTATCTCACTGAAGCAGTCACCGTCAGTATCAATGGTTTGTTCACTTCGGTGACCATGCCTTCTAGAATCTGATTCCTTATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTCATTATTGGGTAAGCGTAATCAGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTTATTTTATTGAATAGATCGTCTATATATCTAACACCTCTTTCTTACACGCGTGAGCAAATCAGTTGAATCTTCTATTGCGCCATTCTTGTTTTCCTGGCATGATAAAGAAAGAATGGCGCAATGAAAAGATCTAATCTCACATATAAGAAAGAGGTGTTTAGATATATGAACACGATCATTCAATAAGAACAAAGAACAGATCTGTTGGCTGTGCACTTTAAATAATGAAGCAGGGACCCGAAGTTTGCTAGTTGTAATAAGGAGTCGAATTGCAAATAGGCATATCAATGAAGAACAA
-+
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
-@082da2de-3990-41b1-9580-3c9754de358f
-AAAGAGATGTTTTACCCCGGGAAAACGGAAGGATGCGTCGGGGATCATTTTTCAGCTCGCTGCACTCAACTATGCATAAGCGAATGGTGATCACTTTGGGACTTACGGTGTTCCTTCACCGTCATTTCGACAGTTTTCTCTCCGGAAGCTAGTGTCTGCCATAAGTCTGGATAACAGGGCACGGTGATACTCCGTGGCGGTGCTTCCTCACCACATACTCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTCTGTAACGCCCCCAGTCTCATAACTTCTTTCAATTGCCGATCATCGGTAATTGAGTTAACTTTCTTACCGAGAGCTGCCGCCCGTAAAAAACCGGAAACGGTCTTTTACTCAACTGGCCCCTTTTTCTGATTTCCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATAGCCCGCCTGCGTATTACTTCACTTCGTTTTGTCATAAACGCTGGCTCCGTATCTGACATGGGTGTCAGGGGGCAAAGCCCTGACCAGAGGCTGATATAATAGCGTGCATGTATGCGCGGTACTGAGTACGCACATACCATCTGTCAGCAAGCTCGAATTACCGACAAAGGCACGGCGGTTTTTGGCAGTGACAGTGTTGTCTGACAGAAATGCCGTCAAAAGCCAAGCGGCAGAATAACGGCAACCGAAACAGTCGAAAAAGTGGTACGCGATATAATCACACAACGCAGATGACAGACAGAACGGAGAAAACGAAAGATGAACAAGCAGCAGCAAGCCGTGTTACTCACTGGCGGGATTCATAAAAGGTCAGGGCCTGACGCTGGCGCAAACTGGACGCACCCAAATGCTGACGAACAGGCTGCCATGTGTGGCTGCACGAACTCGCAGAAGAACTCCAGAACAGCATCAGACACGCTTTGAAGTAGAAAATAGCACAGAGAGATAGCGCTCAGGACAGGATGCCGAAC
-+
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
-@386e2eb7-7569-4439-96fb-b2913fe11877
-GCATCCTGTCTGGGCGGTATCTCTCTGTGCCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGATGCAGCTTCTCACACATGGCAGCCTGTTCGTCAGCATCAGGTGCGTCAGTTTTCGAGCAGCGTCAGGCTCTGACTTTTTATGAATCCGCCATGTTGAGTACGGCTTGCTGCCGCTTTGTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACCACTTTTCTGACTGTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTGGCAGGCATTTCTGTCAGACAACACTGTCACTGCCAAAAAACTGCCAATGCATTGCAATGGTAATTCGAGCTTGCTGACAGGACAGGATGTGCAGATTGTTATACCGCGCATACATGCACGCTATTACAATTGCCCTGGTCAGGGCTTGCCCCGACACCCCATGTCAGATACGGAGCCATGTTTTGCTGACAAACAAGTGGAGAAGTAATACGCGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACGGCAGAAGACCAGGAAATCAGAAAAAGGGCTGCTGAATGCGGCAAGACCGTTCCGGTTTTTACGGGCGGCAGCTCTCGGTAAGAAGTTAACTCACTGACTGATGATCGGGTACTGAAAGAAGTTATGAGACTGGGGCGTTACAGAAACTCTTTATCTGACGGCAAGCGTGTCGGGGACAGGAGTATGCGGAGGTGCTGATCGCTATTGCGGAGAATTATCACCGTGCCCTGTTATCCAGACTTAGCAAATTAGCTACAGAGAAAACTATCGAAAACAGACCGTTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAACGATCTGACGCATCCTTCCTGTTTTCCCGAGGTAAAACATCTCTTT
-+
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
-@09a10a3e-1c9d-4e95-ad82-12c0624f3230
-AAAGAGATGTTTTACCCAGGAAAACGGGAAGGATGCGTCAGGATCGTTTTCAACTCCTTTCATAGCTATGCATGAAAGCGAATGGTGATCACTTTGGGAATTTACGGTGTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCGGGAAGCTAATCTGCAAGTCTGGATAACAGGGCACGGTGATACTCCGTAATAGCGATCCAGCACCTCCGCATACTCCCTGTCCCCGACACGCTTGCCGTCGATAAAGTTTTCTGTAACGCCCCCAGTCTCATAACTTCTTTCCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTACCGAGAGCTGCCGCCCGTAAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCTTTTCTGATTTCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATAGCCCGCCTGCGCGTATTACTTCCACTTCGTTTTGTCATAAAACATGGCTCCGTATCTGACATGGGTGTCGGAGGCAAAGCCTGACCAGGGCAATTGTAATAGCGTGCATGTATGCGCGGTATAGCAATTACATCCTGTCCTGTCAACAAGCTCGGATTACCGACAAAGGCACGGCAGTTTTGGCAGTGACGGTGTTTGTCTGACCAGAAATGCCGTCAAAAAAGCCAAGCGGCAGAATAACGGCAACAAAACAGTCGAAAAGTGGTACGCGATATAATCACACAACGCAGATGACAGACAGAACAGGAGAAAACGAAAAGATGAACAAGCAGCAAGCCGTACTCAACATGGCGGGATTCATAAAAGTCAGAGCCTGACGCTGCTCAAAAAAACTGGACACGCGATGCTGACGAACGAAAGGCTGCCATGTGTGAGAAGCTGCACGAACTCGCAGAAGAACTCCAGAACAGCATCAGACACGCTTTGAAGTAGAAAATGGCACAGAGAGATAACGCTCAGG
-+
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
-@dc22e7ec-1a6d-4e49-8172-2f8f9e828dc3
-TGATAGTACTTCGTTCAGTACGTATTGCTGCGCGCACTCTCTCTGGTCTCGTGGGCTCGAGGATGTGTATAAGAGACAGATCTCTCTGTGCTATTTTCTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTGCAGCTTCTCACACATGGCAGCCTGTTCGTCAGCATCGGGTGCGTCCAGTTTTCGAGCAGCGTCAGGCTCTGACTTTATGAATCCCGCCATGTTGAGTACGACGCTGCTGCTTGTTTCATCTTTTCGTTTTCTCCGTTCATCTGTCATCTGCGTTGTGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTGACATACCCGCTTGGCTTTTTGACGGGCATTTCTGTCAGACAACACTGTCACTGCCAAACTGCCGTGCCTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCATACATGCACGCTATTACAATTACTTTGCTCTCTTATACACATCTGACGCTGCCGACGACAGAGTGCGCGCGCAGCAGTACATGGC
-+
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
-@f96289c0-464b-42b5-ab3c-a20950c7009d
-CGGTGTGCGCGTTCAGTTACATGCTCTATTGCTGCGCTGCGCACTCTCTGTCGTCGGCGTCGGATGTCATATAAGAGACAGATCTCTGTGCTGTTTACTTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTACACGGGTTAGTGCGAAGCTACTGCAGTGGCTATTGCACGTCAGCATCAGGTGCGTCGGTTTTCGAGCAGCGTCAGGCTCTGACTTTTATGAATCCCGCCATGGCTGGGTGAAGCGCTTACGGCGTTTCATCTTTTCGTTTTCCTCCGATTCTGTCTGTCATCTGCATTAATAGCGCAGTTATATCCGCATTACCACACTTTTTCAGGCGACTGTTTGCTGCCGTTGTTCTGCCGCTTGGCTTTTGACGGTGTTTTTCTGGCGAATAACCACTATCACTGCAAAACTGCAGAGTACCATTACATCGGTAATTCAGGCTTGCTGACGGGACAGGATGTGCTGGTGTTAACCGCTTGCCCAGCTGCGCTATTACAAGTTACCTGGTCAGGAGCTTTGCCCACGACGCGTATCAGATACGGAGCCGCATTTTTATGACAAAACGAAGTGGAGTAATACGCACCCAGGCGGAGCTGTCAGTCAACCTGTTCGTCTGACGGCAGAAGAGAGACCAAGTCAGAAAAGGGCTGCTGGATACGTAGAAGCAATACTCAACATGGCGGGATTCATAAAAGTCAGAGCCACGGCGCTGTCTCTTATACCCATCTGACGCTGCCGACGACAG
-+
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
-@ee0359e0-a469-4547-9a5d-3b5c3ea8952e
-CAGTCGAAAGGCGGTACGCGATATAATCACACAACGCAGATGACAGACAGAACGGGAGAAAACGAAAGATGAACAAGCAGCAGCAAGCTACGTATCAACATGGCGGGATTCGCCAAAAGTCAGAGCCTGACGCTGCTCGAAAAATGGACGCACCGATGCTGATGAACAGGCCATGTGTGACTGCACGGGTGAAGAACTCCAGAACATCAGACACGCTTTGAAGT
-+
-4,154,+)%$'#(+3./();>:;8:,$2#'&)/25161449>:>::;>>;A=9()$1&%@@A5,+,+/;-0*,,(+)+(<4.=.--#$$$-)'%'<9;;2A=CI38B5<?:&%&.0811323'2'8+.A=@--=>DB8((844.,4885.0/0..($$&/321/--)*')&%'((()./13@@.88.058,,6(4619)8.4++'($;6<AD?C9..25,+,,:
-@2ace01b4-c39e-4c59-8e0c-80b0972a7814
-TTCAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCATTACGGCTTCTCACATGGCAGCCTGTTCGTCAGCATCGGGTGCGTCCAGTTTTCGAGCAGCGTCAGGCTCTGACTTTTATGAATCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTCGTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGTGATTATATCGCGTACCACTTTCGACTGTTTGCTGCCGTTATTCTGCCGCGCTTGGCTTTTTGACAGGCATTTCTGTCCAGACAACACTGTCCTGCCAAAAAACTGCCGTGCGGATTTGTCAGTAATTCGAGCTTGCTGACAGGACAGGATGTCTAATTGTTATACCGCGCATACATGCGCTATTACAATTGCCTGGTCAGAGCTTTGCCCCGACACCCATGTCAGATGCGGAGCCATGTTTTATGACAAAACGAAGTGAGTAATACGCGCAGGCGGGCTATCCAGTCGCCCTGTTCGTCTGACGGCAGAAGAAGACCAGGAAATCAGAAAGAGGCGCTTTATAGATGGCAAGACCGTTTCCGGTTTTACGGGCGGCAGCTCTCCGGTAAGAAAGTTAACTCACTGACTGATGATCAGTACTGAAAGAAGTTATGAGACTACAGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCTTGATGCCGGGGACAGGGGAGTATGCGGAGGTGCTGATCGCTATTACGAATTATCACCGTGCCTATTATCAGACTTATGGCAGGTCGGCTTCCCCGGAGAAAACGTCAAAAAACAGACGGTATGAACACCGTAAGCTCCAAAGTGATCACCATTCGCTTTCCATGCATGGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCCGGGGTAAAAACATCTCTTT
-+
->@@>?<2*&,$,+5>AEGCCECE,882458<A=H@B>4997=EG8'')*6*1CJEEF@8?-3578:0BB?CGG;765+5<1-D(.9?=@>11@>?MIO=;87D@<BD>=2)3@C8A4;8=EDC;489:;@EEBCB>76+063;961',1888AB62088<;;95**27134,(<>//2&3$(15.*02,0//3<@?4<:C?/*(&&&'%%(($&35)(%&'04$&(-3(49@CBLI@4..:476?:151230//$'%%+,)-;;;?>>?;.'->@=@C=;5=));23B=>:6699.--31@A?<:16=<=C@BB=B4.%%"&,;880'7BACA>>22FBII;:BLG:64DC83E@DG4*+)*.*1;<?=>>@BEAJJD>AB1&'66:7087.2$&$(5887%+.-%&%)1138:>9?@>:;8.8,7452@67?8&17;=6B@<@@FDH=+8:38>>=8+&$)3**$*-,,)('&&-3*-3D+1>??7%%7((,'.:;?6AIF4--;,'%./45((00-0):=82*00BF;2:1135%$%'(#&$&(($,-2:@78?67=;C@?ECB+6)0-02+8>0348&.61@EE;A)B5=;()+30*5(-55:.9?5834<?@6..3('$(:9:@A>G.32394=<891:561&&%51=;+061,,(+,,-4,',:??@861/,1#$'#&'$$%$%*$$+07A?9113&&&1&9;83,-3/.>AB>=<503*,2>35=,7)*)10,8-**(.&114-??0$?:9A@B@9=&+*&(%*'&*,6859<;),1'&)'%%($*&)++0347=:;(-130&&,3/0**++,%+,),99;<B88:<7=A>>8@42565$+344,5A&.4(=.-/*8=40D9821A<82))4468;=C;@<8:AEC>@FC<=GB.66$&'33564.&/14@G;JFI
-@42c446ee-0e5e-4f63-9772-4958f7a55907
-CGGTGTACTTCGTTCGATTTACGTATTGCTGCGCGCGCACTCTCTCTGGTTCGTGGGCTCGGAGATGTATAAGAGACAGCTATTTTCGCCCCTGAAAGCGTGTCTGGATGCTGTTCTGGAGTTCTTCTGCGAGTTCGTGCAGCTTCTCACATGGCAGCCTGTTCGTCAGCATCAGGTGCGTCCGGTTTTCGAGCAGCGTCAGGCTCTGACTTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGCTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGTAAAATTTATTCTGCTTGGCTTTTGACGGGCATTTCTGTCCAGACAACACTGTCACTGCCAAAAAACTTTGCCGTGCTATTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCATACATGCACGCTATTACAATTGCCCTGGTCAGGGCTTTATTACCCATGTCAAGATACGGAGCCATGTTTTATGACAAAACGAAGTACAGGATATTACGCGCAGGCGGGCTATCCAGTCGCTGCTTCCTGTTCGTCTGACGGCAGAAGACCGGAAATCAGAAGGGCTGCTGAATGCGGCAAGACGTTTCGGTTTTTGCAGGCGGCAGCTCTCGTTAAGAAAGTTAACTCACTGACTGATGATCAGGTACTGAAGAAGCTGGACTAAGAGGCGTTACAGGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACGGGAGTATGCGGAGGTGCCAGTCGCTATTACGAATTATCACCGTGCCCTGTTATCAGACTTATGGCAGATTAGCTTCCTGGAGAGAAAACTGCTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCCCACCATTCGCTTTCATGCATAAAAGCTATGCAGCGAGCTGAAAAGCGATCCTGACGCATCCTTCCTGTTTTCCGGGGTAAAACATCTCTTTTGCGGTGTCTGCGTCAGAATCGCGTTTCAGCACTTGTTCAGCGAATGCATACAATTACAGCATTATGTTAAATTTACATAATTGTCTTTAGTCATTGCGCTATGATTTTGTAGGTGGAGTTGTTTTCATATTTTTGATATAAATTCTTTTATCTCCCTCTGAAGCAGTCATCGTCAGTATCAATGGTTTTTGTTCTTCATTGATATGCCTATTCTAGAATCTGATTCTTATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTCATTATTTGGGTAAGCGTAATCAGGATCTAAAAGGATGTAATAATAGATTCTTGTTCTTTTGGCTATTGAATGAATCGTCTGTATATCTAAACACTCTTTCTTACACGCGTGAGCAATGATTAGATCTTCTATTGCGCCGTTCTTGTTTTCTGGCATGATAAAGAAAGATATTTTTGTGCTTCTACCGTTAATGGCTGTTTCATTGGCACGAAGAGCTTGGTGATGAAATGTTAAGCTATTTAATGTTGAAATTATCGATCTTTCCGTGTCAGAAAACGATTCGTCGGCATCATTGATGATTAAGAATATACTTTCTTTTCATTAAAAGACTCTATGCTTTTAAATGCTCTGAGGTTTGTTTTTAGTTTTGTCTTTCCATGGTATTTATTTTTCAACATAAACATGTTAATTCCTTCTATTTCAAGTAGATTGCAAAGGAAGTGAAAATCATCATCACCCTCAACGAAAATGACTTTTTTATAATCATTTATTTTTCTCGGTTTTCACATTTATCTCACCTCCAGCCATTTCAACTGAAAAGAAAAAAATCATCCATATTAAATTGCATTGCTGTAGGTTTTTGAGATTCCTTGTCTCTTGGTCTTATGCTCAGAGACAGGAATACTCAAACTCAGCTAATACATGAATGTTCCCTCTTTCAGTGTGAAGGTAATGAGCCAGTGATTGGAGCATGTCGGCTAAGTATTGACGCCGTGAGATAAAAAGTGAATATGAACAGCTCATCATAATCCTCAATGACATAAAATTTAACATAATGCTACGCACCGCTGTACGCTGAGCGACACCCGCAGATGTTTACCTGAAGAATGCGTAGGATACTAAACTTCGCTGCATAATATGCGTGAAGCAAATTCGCAGTCTCGATCTGCTTTCACGGTTTTCCTCTCCAGGCCCCTAAAATCTGCCATAGATCTGGATAACAACGTCCGCATAGAAATCGACAAGTTGATCTCAGCAACACTTGATCATCGGCATCGGTAGTATCCTCATCAAGCACCGAGAGCCGGCTGACCCTTTTCTGATTTCCTGATGTCATCGCCTTATTGGTATATCGGCTGTAGCTCGTAACATGGGTGTCAGCAAACAAAGCAATTAGCAGCCAGCGTGCATGTATGCGCGTGTGGTACATCCTACAATCAGCCCGAAGCTCGGCGTCTGAGCACGGCATTTAACGGTGACTGATGCCCGTCAAACCGAAGCGATCGAAAGTGACGCGATATAATCACTGCGAACGAGAAAAGGCAGACAGACAAACAGCAATCAGCCTCCAATGGCCGGGTGAATCAGAGCCTGACGCTGCTGGTTGAACGCCGGCTACTGGGAACTCCACCAGAAAATTTCAAACAGCATCGACCGCCAGTAAATAACACAAGTAACGCAGCAGGACGGATGCCCGAACTGGCACAACCAGAGCGTAAGGGAAAATGTCACATAAGGCGCTCTTTACCGCTTCTCGCTCACTGACTCGCTTACGCGCCCGGTCGTTCAGCTGCGGCGAGCGAGATCCAGCTCCTCAAAAGCAGTAATACCCATCCCCACAGAATCGGGGGATAAAGTCGGAAAGAACATACTGCTCTCTTATACATCTCCGGGCGGACTACGAGAGAGTAGCAGTAA
-+
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
-@c4b1881a-d16f-476b-a90a-5e5f701261d5
-GTGTCTGGATGCTGTTCTGGGTTCTTCTGCGAGTTCGTGCAGCTTCTCACATGGCAGCCTGTTCGTCAGCATCGGGTGCGTCCAGTTTTCGAGCAGCGTCAGGCTCTGACTTTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCGTTATTCTGCCGCTTGGCTTTTTGACGGGCATTTCTGTCCAGACAACACTGTCACTGCCAAAAAACTGCCGTGCCTTTGTCGGTAATTCGAGCTTGCTGACAGGACGGGATGTGCAATTGTTATACCGCGCATACATGCACGCTATTACGATTACCCTGGTCAGGGCTTTGCCCCATGATACCCATGTCAGATACGAACCATGTTTTATGACAAAACGAAGTGGAAGTAATACGCGCAGGCGGGTATCAGTCGCCCTGTTCGTCTGACGGCAGAAGACCAGGAAATCAGAAAAAGGGCTGCTGAAATGCGGCCAGACCGTTTCCGGTTTTTACGGGCGGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCGGGTACTGAAAGAAGTTATGAGACTGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAAGCGTGTCGGGGACGGGAGTATGCGGGGTGCTGATCCAGCTATTACGGAGTATCACCGTGCCCTGTTATCAGACTTATGGCAGATTAGCTTCCCGGAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAACTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAACGATCTGACGCATCCTTCCTGTTTTCCCAGGGGTAAAACATCTCTTT
-+
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
-@fcf49bdd-1b50-473b-acae-e35494b55ed4
-GTTGTACTTCGTTCAGTTACGTATTGCTGCGCACTCTCTGGTCTCGTGGGCTCGGAGATGTGTATAAGAGACAGGTTCTGGAGTTCTTCTGCGAGTTCGTGCAGCTTCTCACACGCTGGCAGCCTGTTCGTCAGCATCGGGTGCGTCCAGTTTTCGAGCAGCGTCAGGCTCTGACTCTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTGCTTGTTCATCTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTTATTGTGATTATATCGCGTACCACTTTTCGACTGTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTTGACGGGCATTTCTGTCAGACAACACTGTCACTGCCAAAAAACTGCCGTGCGGCTTTGTCGGTAATTCAGAAGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCATACATGCACGCTATTACAATTGCCCTGGTCAGGCTTTGCCCCGACACCCATGTCAGATACGGAGCCATGTTTTATGACAAAACGAAGTGGAGTAATACGCGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACGGCAGAAAGAAGACCAGGAAATCAGAAAAAGGGCTGCTGAATGCAGCAGAGACCAGTTTCCGGTTTTACGGGCGGCAGCTCTGTTAAGAAAGTTAACTCACTGACTGATGATCGGGTACTGAAAGAAGTTATGAGACTGGGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGGAGTGGTATGCGGAGGTGCTGATCGCTATTACGAATATCACCGTGCCCTGTATTATCCAGACTTATGGCGTTAAACTTCCCGGAGAAAACTGATCGAAAACAGACGGTATGAACACCGTAAGCTCAAGTGATCACCACATTCCTTTCGTATAGCTGGCAATGCGGCGAGCTGAAACGATCCTGACGCATCCTTCCTGCACCTGTTTTCCCCGGGGTAAAACATCTCTTTTTTGCGGTGTCTGCGTCAGGATCGCGTTCAGCTCGTTTCAGCAGTTGCGTACACAATTACAGCATTATGTTGTTAAATTTTTATAATTGTCTTTGGTGTTTTGCTATGATTTTGTAGGTGGAGTTGTTTCATATTTTTGATATAAATTCTTTTATCTCACTGAAGCAGTCATCGTCAGTATCAATGTGGTTTGTTCTTCATTGATATGCCTATTCTAGAATCTGATTCCTTATTACAACTAAGGTAAACTTGAACTTTTGCTTTCTTTTCATTATTTGGTGTTAAGCGTAATCAGGATCTAAGGATGTAATAATAGATTCTTGTTCTTTTATTTTATTGAATAGATCGTCTATATATATCTAAACACCTCTACTCTTACGCGCGGCTGAGCAATGATTAGATCTTCTATTGCGCCATTCTTGTTTTCCTGGCATGATAAAGAAGAAGGAATATTTTTGTGCTTCCGTTAATGGCATTTCATTATGCGAGCTTGGTGATGAAATGTTACTGTCTCTTACTTACATCTGACGCTGCCGACGACAGAGTGCGCGCGCAACAATACGTAAC
-+
-(66:@>;=>;5H5403BDA>C;88:??D>+5,)+)6=?A=B88:8-F;BI@?@CCF??BDDGEAE9:B:CC;5<F?;5>9;%CB=&6;>;&?53EFD:6D<>?;EIECIC<==;((2))&+299BBEDA;2>39@/&738@;::9%%::;>>A?7A@>B@CF:7FGJJK@B@F>CD5HHD=<43;;=IHFNGFBF9:0-<@>=DF99967>@?FB<CD>B-2'6<@BGBCI=JBBC:A:IGC;76>59<>>CDDD@BLE0**1&66.45BGC>BCGB@@ED>>DJMJE;=79>?>C83>2/--7:899=?=@@<>AGBJEQOKA>@?8@:383ABG?>;1*;))C:840@?@A:EE?A767KH98:>=C=;84C,*(+.;<B93C/2A>@A;+*$%%3,7<;=>IC7745:85@DCD?E3;4435;55;>?@C9)8BB?ED;<=7>?AB;3<>6AC;4<8?=><8=71&+)&&<:20278:=9>3B??9817346/*5'+)'.,-8><?HDG<EEBLOL?:70-(;$*#'111;<BF7*845:>16?88.(8-<<DFDF606?A>83>9I@?,-,('5-()('79(4072)/A?@>8:6)(&*+*5C@?FIFK>:(%4-)'$)$&($''+21907BCIA?B-3==(2>A>?C./168&(27*0?=A@E?A@@@?HF>:;:<:24C13@GEB@B>B%/43FICB*@BBD?A@CFKCF?ADB>-;*&?@?BEBF+DFKD?>BEH-5BA@<><GB;-39CGE3.1))$2.',-711<3;?DBCEDIK=5ABDIEC@741.+4:7=878:=:9:4.($##&0'':018-.-8>04'%*3+-&$$$+1?.*/&4,2-&($&4:?>;=?915;@5;BA>>8B>;2:<>9:8=)8$%,62-('$$%$3588$$%&''%&&-0844%%%%)/2A&.9;-A;671,-8:;))8:ABG>+8&&+$+>?:1%$&(*+2<JG8;F>,67<@6:BJ><9?@:9CJFA;'2$-<A<>32A41?99<2++2:<D<841+*/+>>4..+2*1%*'83:6'>@@A>B@AHAC==@A44:;*?DDE==KPLBD@<=>B333395#$($(-6-*-=>>@:;;G?;4159?@B.<AC;ABAD5CHGENKE@>>:F:<DDA@EEFF>6@?@EE>?7H6CAA>@C?B;7@=>D?5B<<(().1GHEAFC@KH978;DD=B8;KJKDD6=&(')/':('%67126D===96%,:<2,13CDF@BD>A:8-FGKG5;DKD;>EIC:;EA,BB=..<8'1./,177CE::4CB9-E6EFF?BEACAEBAD*>;CC@CDFBBC8JFNG>CCNE9C@95B@;;>?</*.+6-&$A@:0:0:<167;;?4&#"(+*($$*(--',%'''<?BC0/*@=85<9A??C?BCH:8B@B7:>940:<>A@')8<=E<FC>7<=2&+*%%%%.3=ABECED7(A)#+0$07=?;<;,0+19:LC7872231'(9??>@BGD@BGDDM=39=>DC=;>)7./##%(.*7-A3IEF88?4:<??:A?A=<01EA=:72+)9..0()&&:<:))'
-@b2415d2f-c741-4c3d-89df-f623f51768a9
-TTAAAAAAAAAAAAAACAATCGTGTGCGCTAGTTCGGTTGGCATTGCTGCGCGCGCACTCTCTGGTCTCGTGGAGAAATCCAGGATGTGTATAAAGAGACATCATTTAAATGAGCTTAACATTTCATCTATAAGCATACTTGCCAATGAAATAGCCATTAACGGAAGCACAAAAATATCTTTCTTTATCATACCGGGAAAAAACAAAGATAGCGCAATGAGGAATCTAATCATTGCTCACGCGTGTAAGAAGAGGTGTTTAGATATGTAAGACGATCATTAATGTAAAATAAAGAACAAAATCTACTATTACATCCTTAGATCTGATTACGCTTACCCAAATAATGAAAAGAAAGCAAAGTTCAAGTTTACCTTAGTTGTAATAAGGAATCAGATTCTAGAATAGGCATATCAATGAAGAACAAAACCATTGATACTGACGATGACTGCTTCAGTGAGATAAAAGAATTTATATCAAAAATATGAAAACAACTCTCTACCTACAAAATCATAGCGCAATGACTAAGTGATTATAAAATTTAACATAATGCTGTAATTACCGCACCGCTGAAAGCGCGCTGAACGCGATTCTGACGCAGACACCGCAAAAGATGTTTTACCCAGAAACCGGAAGATCGTCAGGATGCATTTTCAGCTCGCTGCATAGCTATGCATAAAGCGAATGGTGATCACTTGGGGCGCACGGTGTTCATACCGTCTGTTTCGAAGCTCAGTTTCTATCTCCATGAAGCTAATCTGCCATAAGTCTGTGGATAACAGGGCCTGAAGTGATACTCCGTAATAGCGATCAGCACCTCCGTACTCCCTGTCCCCGACGCAACTTTACCAAATCGTCAAAGTTTTCTGTAACGCCCCCGGTCATAACTTCTTTCAGTACCCGATCATCAGTCAGTGGAGTTAACTCTACACACCGAGAGCTGCCGCCCGTAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCTTTTTCTGATTTCCTGGTCTTCTTCTGCCATCAGACGAACAGGGCGACTGATAACCCGCCTGCTTGCCCAGTATTACTTCCACTTCGTTTTGTCATAAAACACATCCATATCGGCGTAGATTGTCGGGGCAAAGCTGATATCGGGCAATAGTAATAGCGTGCATGTATGCGCGGTATAACAATTACCACAATCTGATCTGTCAGCAAGCTCGAATTACCGACGAGGCACGGCAGTTTTTGGCAGTGGCAGCAGTGTTGTCTGGCTTAAATACCCGTCAAAAAGCCAAAGCGGCAGAATAACAGCAACAAAACAGTCGAAAAGTGGTACGCGATATAATCTACACACAACGCAGATGACAGACAGAACGGAAAACGAAAAGATGAGCTTAAACAGCAACAAACTATTCACTCCAACATGGCGGGATTCATAAAAGTCAACAAGCCTGACGCTGCTCAAACTGGACCTACACCGATCTCTTATTGAACGGGCTGCCATGTGTGAGAAGCTGCGAACTCATGAAGAACTCAGGAACCACCATCTCTTATACATCTCGAATACCCACGGGAATGGAGGTGCGCGCGTGATACGTGGCAGCAACGTAAC
-+
-$$,,++*)))))((('%%&#$###&$'$$)$.--9)-8-$#$%+,9:<924--(($$',43;-+/19380<,,('&&$$'+(-7:87<64.-./%%'$-7.49/4?835<..)1:::CB@4>>*(-&-$&)#$%$$#%##$&&&&),+):6)1%)*.7<>:901&&%&))CFICEBA<;8;13,5;0.5*))::/51482:9<544$$2'$6*0==923/()-58:;<:25/03.735**'&%1(+141*+*/5=@CDE;;7C:5%#)13;<8530)&&+#$*(&137?78:'''57;;.*6;=BAD@<=CDD::C:@AD1);-CDLB2.%$)*@?@AADEC>?:7689&9<:903CD:B?AC/180A2+..-1,808<=9879<,$A6/=9;??B@:=5>=5));DEFB>A>A>;<@2:*;78?7,,(&'#$3,*064?>A8326:-9:3-3(0-+&3/<?7('469?,*4/,7??57*)''%'0446//+)+$1%%),(39CDDB98/839<4<9:5112.(/&)%'08,($&(,576862)*')('%(&(,-+&$#''.025)(*+'&%&+.'./+0,-/)*(&&470.)/+*&'12<AE4=88.((545=AI4+)7,-(/*&%%$(./,.)'.,/2*?72)%$,/944216<B879(%#*9;>>:*(,$$%))4956@?,0>>5-:+$$$$(,.*&'(:47:8>>?3549843?6:88-,%%$##$*,&35*$$$%%*'1%%'',,5254*2+),-'(%';:=>3-12*(-0*%'%&#$$%%$(-*(//2A8=7:;;9A66?1-12.7:66;*(#&'(-(.-.-(()(&'&$$%##&11,$$&'(,1+$$%-.)((-**)+*+11;<FFB=9$*.+/1<<79@9791/&526>=922@C9661/3:341%&&<AA+)%+**##$$,**()$%/45221((()/-79;:A@%&5:<DA<4533-02(47?=03)(,&,,((,--06+0-<A@+-=13@AEA@GEBFBD>158..>D?>A,<+466;;40640$%0145<:76$$%$$%'%''0%'(**+7;>>A@69HHKHA=D22GI<86)-'%&)&24,'%'+%('+'(23.B+1B?E>?753.*)*&##&('*&%$$#$)*'(+74FB<==5467:>9A7>964*):+,+.%&(#%$)$,%%%&6(0*853>345995''.6;6240,(%'$/3(-7>3(;>>><1%&$$&,$#"%#(*-><?>222%),%%%02/$$-.3576??/,*+;,'*$-D;?A?>751'''%%'$&&9;BCA;/$=67=63,;,,-)((+34;<<?7.9.2,--+4583/:9=KJC=CBBD8C7F4?:=29B@>,,@2+4720-'##$%'*3-2<'(:24(**).,(&&3$<:;:BC6;>,1?>?;<*.')'%(*0$&$$%'41.50A326++/7%')0-24,'((.06865-'*&&$$&&(**.3)/04;;=<221/1)20(2)$,1%&-'4<>?-,.-0%(7@*0'((%-&-##&%**03,.*'*4'+/*5&%&%$-6<.=.28%)))((%7C>47(80.0''+')*+$$#%$')**$&(''
-@ece40f73-48e4-4d5e-931b-efee0e570ddd
-GATGTACTTCGTTCAGTTACGTATTGCTGCGCGCACTCTCTGTCGTCAGCGTCAGATGTGTATAAGAACGGTTGTTCTGGGACCGTGCAGCTTCTCACATGGCAGCCTGTTCGTCAGCATCCGGGTGCGATCCAGTTTTTCGAGCAGCGTCAGGCTCTGACTTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCATAACAGCGTTTCATCTTTTTCGTTTTCTCCGTTCTGTCTGTATCTGCGTTTATTGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTTGACAGGCATTTCTGTCAGACAACACTGTCACTGCCAAAAAACTGCCGTGCCTTTGCATCGGTAATTCGAGCTTGCTGACGGGACAGGATGTGCGATTGTTATACCGCGCATACGCATGCACGCTGTACAATTC
-+
-'$($,/12-)-C83.<?@=@<FAAD<5@<4/%***'-1?BB>;7/1,$*//**)/,*%%%&;>45+),-&70,#$'##$%,#%+03+)%,*27:@D->;98<;75A@:?B<;8A:1>B:&&?3.55/1%%&&8.<68?7.4,(+52:8266,5GH3C/JC77)%%%*+%%&%%67288900@02'5+';:<676*$$$++-,;>@FC;D<?CHFNJC?@LDYB>@)?=F652+06)&$048()<9==,$%&&553A:+&%14:>?@??A)9:=>>>787:AAAMKBCJ?=?;KI?B><62.83$$)6>33?C:8690*&+4??BDCC@0(9''@=?63=;<2<AACB?;>FED?FAAED?/(<,+,-/'"&*6A16=>D>@>;93@AC?B7G@D).D>6/==82,2+&%#$&-(**)-?@@?GE?<<=$$((($%1--7'3/78:46(
-@5bb760a4-3566-402d-a25b-b0674ea4c1c4
-GTTGTACTTCGTTCAGTTACGTATTGCTGCACGCGCACTCTCTGTCGTCGGCGGCGTCAGATGTGTATAAGAGACAGGTCTGGATAACAGGGCACGGTGATACTCCGTAATAGCGATCAGCACCCTCCGCATACTCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTTCTGTAACACCCCCAGTCCTCATAACTTCTTTCAGTACCCGATCATCCAGTCGGTGAGTTAACTTTCCACCGAGAGCTGCCGCCCGTAAAACCGGAAACGGTCTTGCGCATTCAACCCAGCCCTTTTCTGTTCCTGGTCCTCTTCTGCCGTCAGACAGGCAGGGCGACGATAGCCCGCCTGCGCGTATTACTTCCACTTCGTTTTGTCGCAAAACATGGCTCCGTATCTGACGTGGGTGTCGAAGCCAAAGCCCTGATAAGACAGTAGCTAAGCGTGCATGTAGCTGCGCCCGGTATAACAATTGCACATCTATCCTATCAGCAAGCTCGAATTACCGACAGAGCCACGGCAGTTTTTAGCAGTGACAATTGTCTGACAGAAATGCCCGTCAAAAAGCCAAGCGGCAGAATAACGGCAGCAAAACAGTCGAAAAGTGGTACGCGATATAATCACACAACGCAGATGACAGACAGAACGGAAGAAAACGAAAGATGAACAAGCGGCAGCAAGCCGTACTCAACATGGCAGGATTCATAAAAGTCAGAGCCTGACGCTGCTCGAAAAAACTGGACTACACCCGATGCTACGGCGAACAGGCTGCCATGTGGCGAGAAGCTGCTGCTTGTTCATCTTTTCGTTTCTCCGTTCTATCATCATCTACGTTAATGTGATTACTGTCTCTTATACATCTCCAGGCCCACGAGACCGGAGTGCGCAGCGGTACGTAACT
-+
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
-@3d165071-e1ad-4397-bcc5-e460e130f807
-GTTGTACTTCGTTCAGTTACATGTGCTGCGCGCGCACTCTCTCTGGTCTCGTGGGCTCGGAATGTGTATAAGAGACAGATTGTAATAGCGTGCATGTATGCAGTATAGCAATTGCACATCCTGTCCTGTCAGCAAGCTCGAATTACCGACAAAGCACGGCAGTTTTGGCAGTGACGGTGTTGTCTGACAGAAATGCCCGTCAAAAGCCAAGCGGCGAGAATAACGGCAACAAAACAGTCAAAGAAGTGGTACTTGATATAATCACACAACACCAGATGACAGACAGAACGGAAAAAACGAAAAGATGAACAAGCAGCAGCAAGCCGTACTCAAGCAGGATTCATAAAAGTCAAGAGCCTGACGCTGCTCGAAAAACTGGACGCACCCGATGCTGACGAACAGGCTGCCATGTGTAGAAGCCTGTCTCTTATACCCCCACATCTGACGCTGCCGACGACAGA
-+
-&(**-.453;>I+2+3=>;:&&%*$496,0*-&16356+/-+0/./,,(<7G7>G=3<.4%.),:=<<9+,*&,'++*')3,(59=9B@@DD?<;6,+)'(%%('.9$=6659;D=AF00>C?66<50-@A9>23=@955./=A9E@=BBDF/+9%%031.<9=OF/34',>=8<(280/2+0>7H@,-*0?I;>B:229=FFA;7==775:,1,$%(2<A?@?>A?<;??AIA0,/(;*,)&''8?/1;+&&&:9CGH;:78/:44<<9$$6/A?@@6A9:G8>6A<:/3.04(@CC?EI@/9FG@>CEFG:51>7>5?>?76*'$%$*8.%$$((9/BC>10?@B06>A%&180CCBC<96:@@H@69>B@C@=>9?D;124666>BM?9@E@6++23<>JCHFBD1//573400/2756'56?>770-*02123(<;8,/44<215%%'$3<?9),%'
-@782a0d64-0ef9-4f73-b2d4-c0683389dedd
-CATCAGGGTGCGTCCAGTTTTCGAGCAGCGTCAGGCTCTGACTTTTATGAATCCCGCCATGTTGAGTACGGCTTGCTGCTAGCGTTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTCATCTGCGTTATTATTTGATTATATGCATGCACTTTTCGGCCTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTGACAGGCACTTCTGTCGGAACAACACTGTCACTGCAAAAAACTGCCATTTTATTTTGTCCGGTGATTCTTCGAGCTTGCTGACAAGGACAGATATTCTGGTGTTATACCGCGCATACATACCACTTCTTCAATCACCTGGTCAGGGCTTTGCCCGATACCCATAAGATACGGAGCCATGTTTATGACAAAACGAAGTGGAAGTAATACGCGCAGGCGAGCTCACATCATGATCGCCCTGTTCGTCTGACGGCAGAAAGACCAGGAAATCAGAAAAGGGCTGCTGAATGCACGGCAAGACCGTTTCCGGTTTTACGGGCGGCAGCTCTCGGTAAAGAAAGTTAACTCACCTGACTGGTGATCGGGTGCTGAAAGAAGTTATGAGACTGGGGCGTTACAGAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGGACTGGGGAGTATGCGGGAGGTGCTGATCGCTGTACGGAGGTATCACCGTGCCCTGTTATCAGACTTATAGCTGATTAGCTACCCCGGAGAAAACTGTGAAAACAGACGGTATGAACACGTAAGCTCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGGGCTGAAAACATTTGAGCGCACATCCTTCCTGTTTTCCCAGGGTAAAAACATCTCTTT
-+
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
-@f14ca0e8-faaf-4e9f-b5ce-5d4874aa0bc1
-AGTACAGCTTGCTGCTGCTTGTTTTCATCTTTTCGTTTTCTCCGTTCTGTCTGTATCTGCGTTGTGTGATTACTATCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGTAACCTTGGCTTTTTTGACGGGCATTTCTGTCAGGCGCTTACTGTCACTGCCAAAAAACTGCAATACCTTTGTCAGTAATTCGGGTGCTGACAGGACAGGATGTACAATTGTTATACCGCGCGCCACATGCGCTTCAATACAATTGCCCTGAGGTCGGGGGCTTTGCCCCGAACACCCATGTCAGATGCAGACCATGTTTTGCCAAACCAGCAAAGTGAGTAATACGCGCGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACGGCAGAAGACCAGGGAAATCAGAAGGGCTGCTGAATGCGGCAGCAAGACCGTTTCCGGTTTTTACGGGCGGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCGGGTACTGAATAAAGTTATGAGACTGAGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGAGGACAGGGAGCTATGCGGAGGTGCTGATCCTCATGCGGAGTATCACCGTGCCTATCCAGACTTATGGCAGATTAAGCTTCCCGGAGAAAACTGTCAATAGTGGTATGAACACCGTAAGCTCCCAAGTGATCACCATTCGCTTTCGGCCCGCATAGCTATGCAGCGGGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCAGGGTAAAACATCTCTTT
-+
-,.;6/-88899=@>9;95888658;=??@>;>9*116I;7<7@=DAD>999/($&-/))(%%%(($$%$3-%%*))*(.05628???<5208;:@>B7(%.9==7BECAA;,,(''&*&'%*+9:===;:7/$&5>8>CC82,&0$%*/-///@??62.&(,***430010,.**%%((/2/<D;80&.@@B@59$'&&(,-?:+',),.&748:,('+++*,;9<-''>?5-+&&&&+)%&&0)1437/,%&<45397>>:07'(./1$',,%&&&'((%$$&'')0676-33.0%'4=5)2)7A@3?ABF?:0).(,''%%&7.0,)18+(;40*337$><85034D)*<:9+&2*+(93@?A8BADC2,?1@,,*.3((1+;;685<87%+<:<<69:%4=@DB:884;8:=49,-)4'((6;>;A;;'<&*).7872>7<A=*2.+,.*5*,()-&(/3+9C@CEEAC@A>AKHA8D@BC5+-,)8??=CJDC<2534@D@=>>EB,*3)-??>@A/.3/88DBDA<83214;9:81(.2314%02<43<)/;D:=1()%%'$$+2108-/%%'@315;4%%,$&$%'4%($$(0/:44415+0-%6//B66CBGEBB00(1'+*/$&56675>=+,-&2*-(%$$%)$%$%',$&))6763-25857..5BB?BD67/54.+:,01<><:%$=@51%%%%%$&&&'-1+6/..*;:%'10225EB>?<=--2266@339:;@EB>?B?>>??-1%0-6/+-1?A?<?81546
-@bb40d038-68bf-4de8-842a-35072f4afd60
-GACATACTTCGTTCCGGTTACGTATTGCTGCGCGCCACTCTCTGGTCTCGTGGGCTCGGAGATGTGTATAAGAGACAGAAGTTTACCTTAGTTGTAATAAGGAATCAGATTCTAGAATAGGCATATCAATGAAGAACAAAACCATTGATACTGACGATGACTGCTTCCAGTGAGATAAAGAAATTTATATCAAAATATGAAACAACTCCACCTACAAAATCATAGCGCAATGACTAAAGACAATTATAAAATTTAACATAATGCTGTAATTGTACGCACCTTTGAAACGCGCTGAACGCGATTCTGACGCAGGCCCACCGCAAAGAGATGTTTACCCCGGGGAAAACGGGAAGGATGCGTCAGGATCGTTTTCAGCTCGCTGCATAGCTATGCATGAAAGCGAATGGTGATCACTCTGGGAGCTTACGATTGTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCGGGAAGCTAATCTGCCATAAGTCTGGATAACAGGGCACGGTGATACTCCGTAATAGCGATCAGCACCTCCACATACTCCCTGTCCCCGACACGCTTGCCGTCGATAAAGTTTTCTGTAACGCCCCAGTCTCACTTAACTTCTTTCAGTACCCGATCATCAAGTCAGTGAGTTAACTTTCTTACCGAGCTGCCGCCGTAAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCTTTTTCACCTGATTTCCTGGTCTTCTTCTGCCGTCAGACGAACAGGACGACTGATAACCCGCCTGCGCGTATTACTTCCACTTCGTTTGTCATAAAACATGGCTCCGTATCTGACATGAGTGTCGGGGCAAAGCCCACGATGGAACAGTGCAATAGCGTGCATGTATGCGCGGTATAACGATTGCACATCCTGTCCTGTCAGCAAGCTCGAATTACAAACAAAGGCACGGCAGTTTTGGCAGTGACAGTGTTGTCTGACGACAGAAATGCCCGTCAAAAAGCCAAGCGGCAGAATAACGGCAGCAAAACAGTCGAAAAGTGGTACGCGATATAATCACAACACCAGATGACAGACAGAACGAGACTATCTCTTATACACATCTGACGCTGCCGACGACAGAGAGTGCGCGCAACAATACGTAACT
-+
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
-@d070ef6f-29a5-43f1-937a-75bc0417dd59
-GTTCTGTCTGTCATCTGCGTTGTGTGATTATATCGCGTACCACTTTTTCGACTGTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTGACTGAGCATTTCTGTCAGACAACACTGTCACTGCCAAAAAACGCCGTGCCTTTGTCGGTAATTCAGTGAGCTTGCTGACAGGACAGGATGCAATTGTTATACCGCGTATACACGCTATTACACAATTGCCCCTGGTCAGGGCTTTGCCCCGACACCATGTCAGATACGGAGCATGTTTTTATAATAAAACGAAGAGGTGGAAGTAATACGCTGAGCGGGCTATCGGTCGCCCTGTTCGTCTGACAGCAGAAAGAAGACCGGGAAATCAGAAAAGGGCTGCTGAATGCGGCAAGACCGTTTCCGGTTTTACCAGGCGGCAGCTCTCGGTAAGAAAGTTAACTCGCGACTGATGATCCGGGTACTGAAAAGTTATGAGACTGGGGGCGTTGAAAAAACTCTTTATCGACGGCAAACGTGTCAGGGGACAGGAGTATTGTCTGGAGGTGCTGATCCTTACGGGTATCACCGTGCCCTGTTATCAGACTTATGGCAGATTAGCTTCGGAGAGAAAAAACTGTCCGAAAACAGACAAATATGAACGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCCAGCTATGCGGCAGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTTCCCCGGGGTAAAACATCTCTTT
-+
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
-@bad94320-94dc-4619-bdf3-053740dbaeaf
-AAAGAGATGTTTTACCCCAGGAAAACAGGAAGGATTACGTCAGGATCGTTTTTCGAACCGCTGCATGTACATGAAAGCGAGTGAGTCACTTTGGGAGCTTACGGTGTTTCTACATACCGTCTGTTTTCGACAGTTTCTCTCGGGAGTAATCTGCCATAAGTCTGGATAACTGGGGCACATTTGATACTCCGTAATAGCGATCAGCACCTCCACATACTCCCCTGTCCCCGACACGCTTGCCGTGAGTAAGGTTTTTCTATAGCCAACGCCCCAGTCTCATAGCTTCTTTCAGTACCCGATCATCAGTCCAGTGAGTTGTACTTTCTTACCAAAGTACCGCCGTAAAAAACCGGAAACGGTCTTGCCGCATTCAGCCCTTGCGTTCCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCATTCAGTAGCCCGCCTGCGTATTACTTCCACTTCGTTTGTCGCAAAAACGCGAAACCATTATCAACCTTGGGTGTCGGGGCAGAAGCCACGACCTATGGAACGGTGTGACCAGCGTGCACATGTGCGCGGTATAACAATTGCACATCCTGTCCTGTCAAGCCAGCTCGAATTACAAATGGCACGGCAGTTTTTTGGCAGTGACGGTGTTGTCTGACAGAAATGCCCGTCAAAAAGCCAAGCGGCAGAATAACGGCAACAAAACGATTCGAAAAGTGGTACCTGATATAATCACACCATGCGATTGACAGAC
-+
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
-@df89b955-2400-4adf-91be-adf7e99293a6
-GTGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTGACAGGCATTTCTGTCGAACAACACTGCTCCTGCAAAAAACTGCACCGTGCCTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCCACATGCACGCTATTACAATTGCCCTGGTAAGAACTTTGCCCGACATGTCCAGATACGAACCCATGTTTTATGACAAAACAGGGGAATTAAGGTAATACGCGCAGGCGGGCTATCAGTCTGTTCGTCTGACAGCAGAAGAAGACCAGGAAATCAGAAAAAGGGCTGCTGAATGCGGCAAGACCGTTTTCCGGTTTTTACGGGCGGCAGCTCTCGTAAGAAAGTTAACTCACTGATGATCGGGTACTGAAAGAAGTTATGAGACTGGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAATGATGTCGGACAGGGGAGTATGCGGAGGTGCTGATCGCTGTACAGATATCCGCGTGCCCTGTTATCCAGACTTACATGGCAGATTAGCTTCCCGGAGAAAACTGTCGAAAACGAACGGGCATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCGCCGCCAGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCAGGTAAAACATCTCTTT
-+
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
-@db9ace37-06f6-44a5-bee7-48352260fd12
-GTTGCCCCGTTCAGTTACGTATTGCTGCGCGCACTCTCTATCGTCAGCAGCGTCAGATATGTATAAGAGACCAGTGATTATATCGCGTACCACTTTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTTTGACGGAGCATTTCTGTCAGACAACACTTTATCACTGCCAAAAAACTGCCGTGCCTTTGTCGGTAATTCGAGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCATACATGCACGCTATTACAATTGCCCTGGTCAGGGCTTGCCCCGACACCCAATATCCAGATACGGAGCCATGTTTTATGACAAAACAGAGGTGGAAGTAATACGCGCAGGCGGGCTATCAGTCGCCCTGTTCGTCTGACGGCAGAAGAAGACCAGGAAATCAGAAAAAGGGCTGCTGAATGCGGCAAGACCGTTCCGGTTTTTACGGGCAGCGGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCGGGTACTGAAAGAAGTTATGAGACTGGGGAGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGTAGTATGCCAGGGGGTGCTGATCGAGCAATACGTA
-+
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
-@467ed196-ddc4-4852-b780-773b91fd58c5
-GTTCGTTCAGTTACGTATTGCTGCGCACGCGCACTCTCTGTCGTCGGCGGCGTCAGATGTGCCAGAGACAGGTCAGCAAGCTCGAATTACCGGCTCTTTCTAAAGGCACGGCAGTTTTTGGCAGTGACAGTGTTGTCTGATAAATGCCCGTCAAAAAGCCAAGCGGCAGAATAACGGCAACAAAACAGTCGAAAAAGTGGTACGATATA
-+
-%%&27>0>=<KG?C@>:97$'32'$%$&)(((*+473CEA=B>=>%'%%2:@=;083,))%$%+'/-7:19D9:0:@79>?87-5.<;7=:-.//+&&&'&*+&*77'.*03.C=@DB>(-5/5DEG3,6BG@>3/4%%#%/078824=52054.,+).1597E8=956.@<223&(('(7:<>B9::37004A>82>786/.+*-,))
-@d10aeab1-d358-468f-aafc-bbe34e3dc5e3
-AAAGAGATGTTTACCCCGAAAACAGGAAGGATGCGTCAGGATCGTTTTCAGCTCGCTGCATAGCTATGCATGGAAGCGAATGGTGATCCTTTTGGGGCTTACGGTGTTCATACCGTCTGTTTTCGACAGTTTCTCTCCGGGAAGCTAATCTGCCATAAGTCTGGATAACAGGGCACGGTGATACCCGTAATAGCGATCAGCACCTCCGCATACTCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTCTACCAACGCCCCCAGTCTCATAACTTCTTTCCAGTACCCGATCATCAGTCAGTAGGTGCTTTTTCTTACAAAGGCTGCCCGCCATAAAGAAACCGGAAACGGTCTTGCCGCATTCAGCAACCCCTTTTTCTGATTTCTGGTCTTCTTCACCGTCAGACGAACAGGGCGACTGATAGCCCGCCTGCGCGTATTACTTCCACTTCGTTTTGTCATAAACATGGCTCCGTATCTGACATGGGTGTCGGGGCAAGCCCTGATCGGGGCGGTGTAATAGCGTGCGTGTATGCGCGGTATAAGCAGTGCACATCCTCAATCTGTCAGCAAGCTCGAATTACCGACAAAGGCACGGCAGTTTTTGGCAGTGACAGTGGCATACGACAGAAATGCCCGTCAAAAGCCAGAAGCTGGCAGAATAGCAACTGACAAAAACAGTCGAAAGTGGTACGC
-+
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
-@2c0c3f29-ad59-4642-a9b4-4898a8b16456
-AAAGAGATGTTTTACCCCAGAGAAACAGGAAGGATGCGTCAGGATCGTTTCAATCGCTACCATGTATGCATGAAAGCGAAGATGGTGATCACTTTGGGAGCTTACGGTGTTCATACCGTCTGTTTTCGACAGTTTCTCTCCGGGAAGCTAATCTGCCGCCAAGTCCTGGATAATAACAGGGCACGGTGATACTCCGTAATAGCGATCAGCACCTCCGCATGCTCCCTGTCCCCGACACGCGCTTGCCGTCGATAAAGAGTTTTCTCTTAACGCCCCCAGTCTCATAGCTGCTTTCAGTACCCGATCATCCAGTCAGTGAGTTAACTTTCTTACCGAAGCTGCCGCCCGTAAAAACCGAAACGGTCTTCCGCATTCAGCAGCCCTTTTCCTGATTTCCTGTCTTCTTCTGCCGTCAGACAGGTGGGGCGACTGATAGCCCGCCTGCGCGTATTATTACTTCCACTTCGTTTTCATCATAAAACGTGGCTCCGTATCTGACATGGGTGTCAGGGCGAAGCCCACAATAGAACAGTGTAATAGCGTGCATGTATGCGCGGTATAACAATTGCACATCCTGTCCTGTCAGCAAGCTCGAATTACCGACAAAGGCACGGCAGTTTTTTAGCAGTGACGGTGTTATCTGACAGAAATGCCATCAAAGCCAAGCGGCAGAATAACGGCAGCAAAACAGTCGAAAAG
-+
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
-@884dc971-e807-4a08-8df2-380ba1ce3b16
-TTTCGACTGTTTTGCTGCCGTTATTCTGCCGCTTGGCTTTGACAGGCATTTCTGGCGAACAACTTACTGTCACTGTAAAAAACTGCCGTGCGGCTTTGTCAGTGAATTCAGGCTTGCTGACAGGACAGGATGTGCAATTGTTATACCGCGCGCATACATACGCGCTATTACAATTACTTTGGTCGAACTTTGCCCCGACACCCATGTCAGATACGGAGCCATGTTTTATGACAAACAGAGGAGTGGAGTAATACGCGCACAGGCAGGCTATCCAGTATGCCCTGTTCGTCAATAGCGAAGAAGACCGGAAATCAGAAAAGGGCTGCTGAATGCTGACAAGACCGTTTCCGGTTTTTACAGGCGGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCGGGTACTGAAGAAGTTATGAGACTGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTATCGAAGGGGGACAGGGGAGTATGCGGAGGTGCTGATCGCTATTACGAATATCACACCGTGCCCTGTTATCCAGACCTTATGGCAGATTAGCTTCCCGGAGAAAACTTTATCGAAACAGACGGTATGAATTACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATGGCCATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCCAGGGTAAAACATCTCTTT
-+
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
-@ec2f0296-df1b-42cf-ae73-23bbee899aa3
-AGTGTACTTCGTTCAGTTACGTATTGCTGCGCGCGCACTCTCTGGTCTCGTGGGCTTCGGAGATGTATAAGAGACAGGTTCATACTGTAATCTGTTTTCGACAGTTTTCTCTCCGGGAAGCTAATCTGCCATAGAGTCTGGATAACAGGGCACGGTGATACTCCGTAATAGCGATCAGCACCTCCGCGCTCCCCTGTCCCCGACACGCTTGCCGTCGATAAAGGGTTTTTCTGTAACGCCCCCAGTCTCATAACTTCTTTCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTACCAGCGAGAGCTGCCGCCCGTAAAGGCGGAAACGGTCTTGCCGCATTCAGCAGCCCTTTTTCTGCAGTTCCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATAGCCCGCCTGCGCGTATTACTTCCACTTCGTTTGTCATAAACATGGCTCCACTGTCTGACATGGGTGTCGGGGCAAAGCCCTGACTCAGGGCAATGTAATAGCGTGCATGTATGCGCGGTATAACAATTGCACATCCTGTGTCCTGTCAGCAAGCTCGAATTAAACAAAGGCACGGCAGTTTTGGCAGTGACAGTGTTGTCTGACCTGTCTCTTATACACATCTGACGCTGCCGACGACGAAA
-+
-#$$$%$;=@39E/-&:5:@CAEBDE864/)./-*()%#%/+=18;9;<2-5.+*'20;-1231&(59:.//.1//).492,%$$"$&%%&'+))*.GB851/.4@CH?A73;&<%)+=:(<AFE<@@83,%$'$&63<1;>BD@=-*5-*(/09:;;42,,16211462/78A:10*++0475%)&6-6946:5::<@HDA?<=-;,*//442-<CFG=BA,'&,*,?;?;7+)*+233000*(+).'5*5998?@>>DC>8C63:74==:B.(F?1)2+,4-,=69C>6<@:289=:3$$)%&(*2:<7CAA@?99923*%05$%3.-8),%*7;<:B7A8CB78/4<0;;66788./*%-)5AA=?:=A<=MB>B9/02,0=@@9EEC55>70?DB94==6--:2;>9?7630,551)04-..:<<7:*8<?7@C?41<B66=>><;1+-33$)%$&$&/+8<=>>1467*%9&.32814-)>?@8>0*(20</471'/&(:<688*'858+,,&%((2.3*34*)'&8+,+/),'37++1)('&&*.1.1+9'>247A1.%'%&%&(/;770,4828::62==<GE9;8096:3)'-%&*/0)>+C631,034=B=;9=?.<:77@<C<=*=B>A@CB:A87-,+%
-@456e561d-8f01-4b74-af7c-e60e8d45bde4
-TGCCGTGCCTTTGTCGGTAATTCGAGCTTTGACAGGACAGGATGTGCAATTGTTATACCTGTACATACATGCACGCTGTACAGGTACCCTGGTCGGGACTTTGCCCGACACCCATGTCAGATACGAACCTGTTTTATGACAAAACGAAGTGGAAGTAATACGC
-+
-65@;6D4@B:CA:7=,28:>:<:54@<<1&)*0)6321(7?EA0G>EEDEJA<9331--,)#$99?CB8,,%&==;;*4/(%#$-$)-A=671=&)&#6661+-.,,)47EFD@;3&A44A=;/'#$&%$')052>AC4@359:88'((9-/,',-)*.)1$%
-@ccf94813-0dfd-4442-9c2f-172202d23571
-TTCGAGCTTGCTGACAGGACAGGATGTACAATTGTTGCCCTGCGCAGTACATGCACAGCAATACAATTGCTGAGCAGGGCTTTGCCCCCAGACACCCCATGTCGAATGCGGAGCCATGTTTTATGACAAAACGAAGTGGATAATACCGCCTGAGCAGGCTATCAGTCCGCCCTGTTCGTCTGACGGCAGAAGAAGACCAGGAAATCAGAAAA
-+
-%()''2BEEA?@I=-(0-,'')8??6+%4''(.$'&%()$%%#&(&$%%),+*)$-,(*%%&++)+)3&$$&#%*'24<559>6662'&%&$*035538///6('*&'/&)%(00153A>;4198;855-,5-/0)9')&*)*(&#%))+()$<+&/>@=3*1),$$,39:49,:60:79+5.-&,,.)4.,2169561>=699232+:5(&
-@6c76a1f9-8280-47e0-8f71-15a7788c9dc8
-AGCTTGCTTTGACAGGACGAGATGTGCAATTATTTATACGCGCATACATGCACGCTATTACAATTGCCCTGGTCGGGCGCGCCAACACCCATGTCAGATACAGGAGCCATGTTTATGACAAAACGGGGGTAGATGTCTGCGCAGGCGAGGCTATCAGTCGCCCTGTTCGTCTGACGGCAGAAGAAGACCAGGAAATCAGAAAGACACTCTGAATGCGGCAGACCGTTCCGGTTTTACGGGCGGCAGCTCGGTAGAAAGTTAACTCACTGACTGATGATCGAGTACTGAAAGGGGTTATGAACTGGGGCGTTACAGAAAAAACTCTTTATCGACAGCAAGCGTGTCGAGGGGACGAAGTATGCAGGTGCTGATCCGCTATTACGGTATCACCGTGCCTGTTATCAGACTTATGGCAGATTAGCTTCCCGGAGAAGCTGTGAAAACAGACAGTATGAACACCGTAAGCTCCAAAGTGATCACCATTCGCTCATGCATAGCTATGCAGCGAGTAACGATCCTGACGCATCCTTCCTGTTTTCCCGGGGTAAAACATCTCTTT
-+
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
-@fac91ddd-a0bf-4c28-a779-d30bff765453
-AAAGAAGATGTTTTACCCCGGAAAGCAGGAAGGATGCGTCAGGATCATTCCATGCTGTAACTATGCATGAAAGCGAATGGTGATCACTTTGGGAGCTTACGGTGAACGTACCGTCTGTTTTCGACAGTTTCTCTCCGGGAAGCTAATCTGCCATAGAGTCTGGATAACACGGGGCACGGTGATACTCCGTAATAGCGATCAGCACCTCCGCGTACTCCCTGTCCCGGCCGCTTGCCGTCGATAAAGTTTTCTGTAACGCCCCAGTCTCATAACTTCAGCGCACAGTACCCGAATGTCAGTCAGTGAGTTAATAACACAGGCTGCGCCGTAAAAACCGGAAACAGTCACCGCATTCAGCAGCCCTTTTTCTGGTTTGCAATGCCTACTTCTGCCGTCCGGACGAACAGGAGCGACTGATAGCCCGCCTGCGCGTATTACTTCCACTTCGTTTACATTCGTAAAACATGGCTCCGTATCTGACATGGGTGTCAGGGCAAAGCCCTGTTCCGGGGCAATTGTAATAGCGTGCATTAACCTGCGCGGTATAACAATTGCGCATC
-+
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
-@ce62bc1e-78e9-4bc7-9e1b-b8dd3604f2b6
-AAAGAGATGTTTTACCCCGGGGAAAATAGGGAAGGATGCGTCAGGATCGTTTTCAGCTCGCTACACTCTTCTTCATAAGCAGATGGTGATCACTTTGGGAGCTTACGGTCGTTCGCCACCGTCACATTTTCGACAGTTTTCTCTCCGGGAAGCCATCTCTGCCATAAGTCTGGATAACGGGGGTGGTGATACTCCGTAATAGCGATCAGCACCTCCGCATACTCCTGTCCCCGACAACGCGTCGATAAAGAGTTTTCTGTAACGCCCCAGAGATCTGCATAACTTCTTTCAGTACCGTCATCAGTCCGGTGAGTTAACTTTCTTACCGAGCTGCCGCCAAAATAAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCTTTTCGGTTCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACGGTAGCCGCCTGCGCGTATTACTTCCACTTCGTTTTGTCGTAAAAACATGGCTCCGTATCTGACGCTGGGTGTCGGGCAAAGCCCGATCGGCGAAGTGTAATGGCGTGTGCATGCGCGGCAACAATT
-+
-1(%'18310;;D6//4-.$)//03+%#$&,%.02,)56,641+3?@:.(<?K;15-:93)**%%%#%&%(%%&)$$$***'',.)*-0138.....',3-3:;;56'(&$&&,1%%$$(+0,)%%%%+-14:;75=8;?<<99;&3&&$+*+'%)(+$0:6;;33786<B8:<70%%&#&'''%#$+*+$$):6;9:<><<>?AA=:6:A5::;7:-3+.*%75679;>I<0,(())(')%8:556=<5+-</2F;1.('&&*(((((((++).5)$$(+++')655;681:400+$&5<7?:8((<*0;<5CCDAD56>>>A9./1/)*>?BBB<<;()*''+/346789.1.17;$+8:AA789#?6:<*(**)*12668@:C.4?,@298<?BC2;>AFACB?>C@EC=<87,'-),,.),$%&*#04.555/343034))&%66=B;:<;,549?2))&%'/0//(.%($(,,6?A@=9<39.($"%%'%%%(+$)%0)+')%&%$$%,#&#$$$$/%%++.#%%&&$$%#-++2'-$%'%%,-.-/
-@6c74468c-23ee-4c55-a905-4ac27419f7ca
-AATTGCCTGGTCAGGGCTTGCCCCGTTTTACCCATGTCGAATACAGGCCATGTTTTATGACCATAAACAGGAGGTAGATAACACGTAAGTATTATCAATCTCCCTGTTCGTCGACAGCGAAGAAAGACCGGAAATCAGAAAAAGTTTGCCAGATGCATGAATAATTCCGATTTTGCGGGCGGCGGCTCTGATAAAAAATTAACTCACTGACTGATCGAGATTTGCTGAAAAGAAGTTATGGAACACAGAACGTTACAAACTCTTTACATCTCGACAGCAAACGATGTCGTGGGGACAAGGGAAGTATGCAGGTTGTTTACAGTCGCTATTGCGGGTATCACCGTGCCCCTGTTATCCAGACTATGGCAGATTGCTTACCGGAGAGAAAGGCATCGAAAACGGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTACGCTAAGATCGAGCTAAACAATCCTGACGCATCCTTCCTGTTTTCCGGGGTAAAACATCTCTTT
-+
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
-@401f4d56-6764-4256-b222-6960145f8306
-AAAGAGATGTTTTACCCCAGGAAAACAGGAAGGATGCGATCAGGATCGTTTTCAGCTCGCTACCCATAGCTATGCATGAAGGCGAATGGTGATCACTTTGGGAGCTTACGGTGTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCGGAAGCTAATCTGCCATAAGTCTGGATAACAGGCACGGTGATACTCCGTAATAGCGATCTAACACCTCCGCATACTCCTGTCCCCGACACGCTTGCCGTCGATAAAGTTTTTCTGCTTAACGCACAGTCTCATAGCTGCCAGTACCCGATGTCAGTCAGTGAGTTAACTTTCTTACCGAGCTGCCCGCCGTAAAAAACCGGAAACGGTCTTTTACGCATTCAGCAGCCCTTTTTCTGATTTCCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACCAATCAGCCCGCCTGCGCGTATTGCTTCCACTTCGTTTGTCATAAAACGTGGCTCCGTATCTGACATGGGTGTCGGG
-+
->1($/+-76><;2****)'.)>EBA./1=9;>3/923**51*>A>8>?A;;.734=,9##'##$$&%()07977:/)$%-*:>56;4+,7>:6<)***++..,+//.0<465/@1?)96<=:=>22CEJC=?D?;@CAR387%=9C9=&.1A9;<;<?;;;''%&%1628<>B76-&&39--'/ACB@;8:6223<;43/00-*5$&&'))*/$-$6298/348<@=?FEBAC::>6((6<=><:@=@;/4++CHPI?;2/++.56>2504748::@-'/%..'%)(,1.-3)'$()6<8/'3*.7;2A7<1178;/2*)&'/.,8=<1876'.59:?@@99999&'*)&-*0:<<610).4?9B>79326/552111185-,*%:@'699>=?@1,*(*)49=:3A;=B;1181,0,,+200''+)+**@AI>77-1,-'&&',.%,-.+,'*6:<?ABI>>E<;?AB06)1%+:>>B9B<9B.8-'',*021()*&('
-@632dd2fa-e55c-4f6a-9b26-7e68e582932c
-AAAGAGATGTTTTGCCGGGAAAACAGGAAGGGATCGTTTTTCAAGCTCGCTGCATATGCATGAAAGCGAATGGTGATCGCACGGGAGCTTACAGTGTTTCATACCGTCCTGTTTTCATAGTTCTCTCGGGAGCTAATCTGCCATAGAATCCGGATAACAGGGCACGGTGATACTCCGTAATAGCATTAGCGCACCTCGCAGCACTCCCCTGGCTCCCCATTTTGCCGTCGATAAAGTGCAACGCCCCCAGTCATATAACTTCTTTCAGTACCGATCAGTCAGTGAGTTAACTTTCTTACCGAGAGCTACCGCCCGTAAAAACCGGAAACGGTCTTGCCTGCATTCGGCAGCCCTTTTTTCTGATTTCCTGGTCTTCTTCTGCCCGTCCGGGCGAACAGGGCGACTGACCCGCCTGCGCGTATTACTTCCACTTCGATTTTGTCATAAAACATGGCTCCGTGACATGGGTGTCG
-+
-=1&(%5;==A?=7$25-/8+:030(7<./,%/7;?@FALFC?;<@6;C::=.$$$*6;@@:>9D=>91183+1@:4+>&%$%$(&'&222.($,&)77/(,1479:++=7803<1*)'&59=::'/(#''(&/<<=9C;';;/')$%%%%)'-=?>><7A.*($%26><43/.07=;;00.951&''%$%%%&./'6'(&%%##'&+*')(''2596/''()+-169=CBC<77,&2%$((+*-*+*'''&)##%%$$"%)4;><3)-0,)*)+,*&)**(*.-+59;=>78=D2.@>;620*-.++(567:9.)1?ADF>BA26.519378865+&&$&814*-$(+'%**))2A@><=5:8B=0(0756,,+79;>:0/*045))9,/0/((-,,9?GB68(/0/56;8BBA94+)((&*.3486%(&#$'%'$-2EFC;B25>AAD?:B4;FE45+1-.777-,(+)'&%
-@6155ab1d-49b0-412b-b733-4e3032883ee3
-GACAGCCCATGTCAGATACGAACCATGTTTTATGACAAAACAGGAGTGGAAGTAGCCACGCGCAGGCGGGCTGTCAGTCGCCCTGTTCGTCTGACGGCAGAAAGACGGAAATCAGAGAAAAAGGGCTGCTGAATGCGGCAAGACCGTTTCCGGTTTTACGGGCGGCAGCTCTCGGTAAGAAAAGTTAACTCACTGACGGTGATCGGGTACTGAAGAAGTTATGAGACTGGGGCGTTACAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGGAGTATGCGGAGGGTGCTGATCGCTATTACGGAGTATCACCGTGCCCATTATCCAGACTTATGGCAGATTAGCTTCGGAGAAAAACTGTCAGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATACAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCCGAGGGTAGAAACATCTCTTT
-+
-*2-)407;??>9B8:>E>2,+.<<B?EKJICDDFFC?@:6+.'$02??A707)9%%$$&$554-/>?/03<<:42,/44<CCEEFJIE84>8JEEAA?=;=:&'((0125<5@?:5(=?1/.*:<4E.=?CDHCDG49B:;9>=:9?>C0823J=8/$&$*:C?D-)FBF<>D5;6))(353,;047/*9<CAA@,%$%'''%?.27A<9:@;6072BHGA@B>E@?>9@1273>@<;'*12:A@F?GIFEBFE<2-0:<<$95H?8D.4BAF51=0-56GC>;>39?78?C:9AE@7A.-;6<?=B)*1)8*'<1123F=::'$$+=**GBD:6BADE.45:5:91+C>A0C5.1',/2-,->776)(BFGB?;=ED18>9977<>D?03356'<::<=HIGB?>98:54//5--'&',>CA=D9771933*%%.)3>:9<1.$%.742>>>AFFKDD>@D;<A?>ADFC@;J>9<*(%*)**'#,A9?@?GC6IGI
-@ea1ef195-81f5-4c7a-8560-1aac0bf0a13a
-AGAGATGTGTTTTGCGGGGAAAACAGGAAGGATGCGATCAGGATCGTTCAAAACTTCGCTGCATAGCTATCATGAAAGCGAATGGTGGTCTTTTGGGGCGCGGTGTTCATACCGTCTGTTTTCGGCAGTTTTCTCTCCGGGAAACTAATCTACCATAGAATCACGGATAACAGGGCACGGTGATACTCCGTAATAGCGATCAACACCTCCGCATACTCCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTCGCGCCCCGGTCTCATAACTTCTTTCAGTACCGATCGCCAGTCAGTGAGTTAACTTTCTTACCGAAGAGCTGCCGCCCGTAAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCCCTTTTCTGATTTCTGGTCTTCTTCTGCCGTCAGACGAACAGGGCGACTGATAGCCCGCCCGCGCGTATTACTTCCGCTTCCGTTTTGTCATAAACATGGCTCCGTATCTGACATGGGCTGTC
-+
-3(570,*&*+/40$&%)@@)3J=3/A<9B8B:<93''3724B=8857,)&&%$$%*3448*(&&)$)3,,($../>>C@112+)(&&&,$"%&&&.012--0637=<9;;=987=?8;658)(#$&&%48B<<B:;*(#%%/%$.7=B<@2)79/0,+.,-3.6?CB?====:(.18;8=EB=?4<?7<:=DFC?B831./%&4588A;66=3377?6:8899:<92.,0&4%6:>@>ACBFGIDKK<&4;@AA;=)/545441%,24$:$$$$$4:89:04/10'&262-;%%'*,.2+<;23:FE?/(;>=<=>>:40/-%&5?E?CDBDE@>ADEG>?>FG01>@+B,3::H?=>A2<::8;@2(:$:<-,497>7@<=6)+-%*33563331+)138<B:<?>76;32.%*(&#%,/',)*--1/12:3,;?<A><B<=??8A*;?@(+209@744@117651$(5=@E:A;C5-F4MC=B@4176;933
-@8337f1bf-dee5-439d-995c-3b65b6ba25f4
-TACGGAGCCATGTTTGTAACCAAACAGGAGTGGAAGTAATACGCGCAGGCAGGCTATCAGTCGCGCCCTGTTCGTCTGACGGCAGAAGAAGACCAGGAAATCAGAAAGGGCTGCTGAATGCGGCAAGACCGTTTCCGGTTTTACGGGCGAAAAGCAGCTCTCCGGTAGAAAGTTAACTCACTGACTGATGATCGGGTACTAGAAAGAAGTTATGAGACCAGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCGCGGGGACAGGGGTATGCGGAGGTGCTGATCGCTATTACAGATGTCACACCGTGCGCCTGTTATCGAGACTTATAGCGGATGCTTCCCGGAGAAAAACTGTCGAGAAAACAGCGGACCCGGTATGAACACCGTGGCTCCCAAAGTGATCACCATTCACTTTCATGCATAGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCCGGGGTAAAACATCTCTTT
-+
-&%&/20+889789;7$&02585711&&$0.?8;4*.70003&%%.-++>-'63/-36705.3%&AHHJHAA>5.&4)/0)&.69073(((;C;3()(24995.,32%&.1;CA=78/999;/26$%,/&(%)/:(-$)*/:4$$&+2,($$$$&&();:54$@'-+1&5/>;BAAD@C@<88C=--96:61++(+,(/43%%;6-):8@B?4++%))&%'(2?DAB>@1=/<4<BDF@F@GFE=8;;72341??>EBB6/3),*.7@;..*,).++($%,15==;74,0015..5,-,.*%)'%%+-%&*31)4'&),+((,.+&5''9:8A:96.8<&)26)$$',>D@7100-;:356+21*+$+*,-($&$%'3%73#$&1398><>=;47+065386CC@>@A:8>92.(()8)18BI9><=;-2232:910+',,%%589;8AC75;<00;=ABB;>=67987$',9@@JD(07&,-.*3375+316-6024
-@ed420a81-0710-489f-982d-cee487075d87
-GGAAAACAGGAAGGATGCATCAGGATCGTTTTCGAAACTAACATAATATATGAAGCAGATGGTGATCACTTCGGGAGCTTACGGTGTTCATACCGTCTGTTTCGACAGTTTCTCTCGAGGAAGCTAATCTGCCTAAGTCTGGATAACAGGGCACGGTGATACTCCGTAACGATCAGCACATCTTATACTCCCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTCTGTAACGCCCCCAGTCCTCATAACTTCTTTCAGTACCCAAGTCATCAGTCAGTGAGTTAACTTTCTTACCGAGGAGCTGCCGCCCGTAAAGGCAGAGCAGTCTTGCGCATTCAGCTGCCCAGCCCGCTTTTTTTTTTTTTTTTCTGATTTCCTGGTCTTCTTTGCCGTCAGACGAACAGAGGGCAGCTAATGATAACCCGCCTGCGCGTATTACTTCACTTCGTTTTGTCATAAAA
-+
-+-3<BA4/<<8:78,$#%%(1.7?7-+&-.:3/%&%#%&%%&&(()('%'')('$%118A+/;0-&.'$%&'%,/*+00/24.3469,/$%#(-/186-,0210<<7B=?=:6/2)(%4:6:1-.==6@;4&)$#'*+,&%'(/123/:/;*22(,30/1**5/0++&()))++&+-',(('%$((('01580409;>>=:56.-%$#$%389@CA6.EG5((9CHG<1+)*))3556660.7448<C@A<:6;B9BC.842&)(''$&&02*4821'--&-1(662%&#&+;47/%&*&&-.(/4:/77588507BD6&12+,)(()+,+&&%1$<:<1)2$,-,,0144421$)67DBBBJFECG>>8;3922*;=@./)%*9:5-$%'%"%&';@9@A;327.,0'(**,&$$#$&##'$$%4527874(2('&%&&(%)+).-9<>4)*4EC90<$$#%'&
-@59335f9d-2638-4634-ba8f-e2f658dd126e
-GTTCGTCTGACGGCGAAGAAGACCAGGAAATCAGAAAAGGGCTGCTGAATGCGGCAAGACCGTTTCCGGTTTTTACGGGCAGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCAGGTACTGAAAGAAGTTATGAGACTGGGGGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGAGTATGCGGAGTGCTGATCGCTATTACGGAGTATCACCGTGCCCTGTTATCCAGACTTATGGCAGATTAGCTTCCCGGAGAAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATCTTTGACGAGCTATTGATCCTGACATCTTCCTGTTTCCCGGGGTAAAACATCTCTTT
-+
-AJGB>3@7MCG-3:''955,26,/)1//9E;B33=;3**7@9:8)'''/049(0DEFFDEH>IFB&*&.<=@6?AA;>=+'5/*8?B>AF28?664<98?DB>?<DA86<GA==4,GE3+/&.(;>?@BAJ9/98=;GA?C@HH;9*-85<68=A@;;76A7<D>:2222>BCB@=<044=</')A:6C)2??;319366A@868,-%'C=>>?;6E66;;>:1A16/98.&.-34;C>ECDF(DCB&&B8>>''(8@8:=<<>@:D3<=>*06)-0&&+&9CCE@B92;4;8715/628$'5:+..7;6%078::2=<2==>412,+)A6==>DE>98JK@@6/+6/4869;700((-3+(&$)%&$#$))346/0,+$(4;=9;<B@?E*.>$.,,9=?HD@<8>;<IEC
-@e0998300-6336-4a3d-bb92-51572c44c417
-GGAAAACAGGAAGGATGCGTCAGGATCGTTTTCAGCTCGCTGCATAGCTATGCATGAAAGCGAATGGTGATCACTTTGGGAGCTTACGGTGTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCGGGAAGCTAATCTGCCATAGAATCACGGATAACGGGCACGGTGATACTCGTAATAGCGATCAGCACCTCCGCATACTCCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTCTGTAACGCCCCCAGTCTCATAACTTCTTTCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTGCGAGAGCTGCCGCCCGTAAAAAACCGGAAACAGGGTCTGCCGCATTCAGCAGCCCTTTTTGCGGTTTCCTGGTC
-+
-0=/:A7-*9E<E@=8=7?20@>CDC9<<DCB);34@??ABGGH:C?HBC?>?@=>?<C4;:88?=3;AE/*C578:>9<;1<87477*.>AC=F;<<B>3$$(57;F47==8=5CEJ@<8%5&:$%%%$)&->B=AB>@=+'5&&&+)&&?BDDJHF53<<;KIHFHE;2A,?=@BA549:7/+.@*:>$:?02-/((/3@69/64=?B?><8:176))1AABEA<@B=EA8'&5,6K>B84<>@FHKGE;553'0-@---,+3289=(:2=DGIG@BC=C;4C<=9<96966=C?21)*0;763$2/'(:?CCACDA?==@@EIIEG;A</1+10-&*'$&&%/8<=@:<-.$&'$&&%%%%%%+$&$&15<.04'''%
-@b45a17f1-0345-4fb6-a33c-200285e4e92d
-CAGGAAATCAGAAAAGGGCTGCTGAATGCGGCAAGACCGTTTTCCGGTTTTACGGGCAGCTCTCGGTAAGAAAGTTAACTCACTGACTGATGATCGGGTACTGAAAGAGTTATGAGACTGAGGCGTTGCAAGAAAAAACTCTTTATCGACGGCAGAAGCGTGTCGGGGACAGGGGAGTATGCGGAGGTGCTGATCAACTATTACGAATTATCACCGTGCCCTGTTATCCAGACTTATGGCAGATTAGCTTCCCGGAGAAAACTGTCGAAAACGGGCGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAAGCGATCCTGACGCATCCTTCCTGTTTTCCCGGGGTAAAACATCTCTTT
-+
-83>:)4;03>,9)2,':A?;==688?77C19=<<D=A61=?EB*5-4><=-.?367'%:AD<:;7<7//-0.+8-.CD<>965=GH@DD?=<3-B10;<;;@??+877@>:/./0CA;.<&0,.&-0$,%''79FDE?<E?HJID:=95.,.&0$&&8==J5,A',<@I=;>8::29BD>>?4987FAA?>=82:&&/04990,1%&%,31,.275?5::=A)A>@..D9CA77657;B:G7BCB?@AFE7=B?@EB.3D<ACA=A@BIJA;$+$8'-8@CA>><1-2.2'('+62>:+,+5;<18D<=@DK:</.@@<B@>BJ=85DA<C73301700%000169%(.;@++-CJ4=>B=67=>B?BMC;<SC7::%'/29BEJIBE@C?4FHP
-@1ce56370-4094-46c7-9d23-b6e0d6c32099
-AAAGAGATGTTTGCAGGGAAAACAGGAAGGATGCGATCAGGATAGTTTTCATCGCTGCATAACTATGCATGAAAGCGAATGGTGTGATCACTTTGAGGGCTTGGTCGTTCATACACCAAATCTGTTTTTCGACAGTTTCTCTCCGGGAAGCTAATCTGCCATAGAAGTCTGGATAACAGGGCACGGTGAAATGCTCCGTAATAGCGATCAACCTCCACATACTCCCTGTCCCACGACACGCTTGCCGTCGATAAAGAGTTTTCTGTAACGCCCAGTCTCATAACTGGCACAAGGTACCCGATCATCAGTCGGTGAGTTAACTTTCTTACCGAGAGCTGCCGCCCGTAAAAAACCGGAAACGGTCTTGCCGCATTCAGCAGCC
-+
-J5'&-97..:=.$&%/.,/5?<1+=@=>:4.%'.$$&3--1,&(*0?>-/')+*./7</5,,/68//=89117*3<66<</2-).,'+?0///*)$%%$%%%$&)%&1,*$%&$&%8**)':%,4554,43/506>CC3<2E6F,0C><?BA@=>@>879)%/$(&$6;4;==7443->0.0/2+/-*,-($"&(29::;<935521,=&&*,25:%;23.,89>8:933:8'.6>@@>8:??24/(;B??>BD/,)<89IB(.%,++,',.0)169>A&&*)*-'&&).$&&'.5=EA=924*%%$'0;&-4:1EGED95;?>966+;;?9)&/94+%-56:C<=GM@=<:;C2518*8&+-../4>A8B?;-1/4'4$$$
-@f4d1033e-fb7b-45f1-bfc0-752c8b7c7383
-CTTGCTTCGTTCAGTTACGTATTGCTGCGCGCGCACTCTCTCTGGTCTCGTGGGCTCGGAGATGTGTATAAGAGACAGATTGTTTAGATATATAGACGATCTATTCAATAAAATAAAAGAACAAGAATCTATTATTATTACATCCTTAGATCCTGATTACGCTTACCCAAATAATGAAAAGAAAGCAAAAGTTCAAGTTTACCTTAGTTGTAATAAGGAATCAGATTCACAAACTGACATATCAATGAAGAACAAAACCCTATTGATACTGACGATGACTGCTTCAGTGAGATAAAAGAATTTATATCAAAAATATGAAACAACTCCACCTACAAATCATAGCGCAATGACTAAAGACAATTATAAAATTTAACATAATGCCGTGCATAATTGCACAAGAAACGCTGAACGCCCAGGTCTGACGCGCAGACACCGCAAAAGAGATGTTTTACCCAGGAAAACAGGAAGGATGCGTCAGGATCGTTTTCAGCTCGCTGCATAGCTATGCATGAAAGCGAATGGTGATCACTTTGGGAGCTTACGGTGTTCATACCGTCTGTTTTCGAAGTTTTTTCTCTCCGGGAGCTAATCTGCCATAAGTCTGGATAACAGGGCACGGTGATACTCCGTAATAGCGATCAGCACACTCCCGCATACTCCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTCTGTAACGCCCCCAGTCTCATAACTTCTTTCCAGTACCCGATCATCAGTCAGTGAGTTAACTTTCTTACCACCGAGAGCTGCCGCCCGTAAAAACTGTCTCTTATACACATCTTGAGCCCACGAGACCAG
-+
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
-@ae0853da-5e92-45c3-b88b-20fed2a4964f
-AAAGAGATGTTTTACCCCAGGAAAACAGGAAGGATGCGTCAGGATCGTTTTCAGCTCGCTGCATAGCTATGCATGAAAGCGAATGGTGATCTTTGGGAGCTTACCAGGTGTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCGGGAAGCTAATCTGCCATAAGTCTGGATAACGGGGGCACGGTGATACTCCGTAATAGCGATCAGCACCTCCGCATACTCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTCTGTAACGCCCCAGTCTCATAACTTCTTTCAGTACGATCATCAGTCAGTGAGTTAACT
-+
-.($+)('7;JJE=;9;;,*??;IGH*&AIBJ@><53.).:0>CCAFAPLM84?7?@B0&,2<.58?;67=?D<?@=3A@854=9*/.0*&'#('%)0++0004%0&,*94B=D755AD=7B=CCAA8:=?61<ADG8@D=E6D49<;10@BDF?C@BDD:C<=5-9.1460*+1$*43?;?BDDGFC1,%'=867;<:2@:.($<?=C3===7?*7259;;8:22:=HKG7975<2/11))+);>@C?JR=%:;BGZREC>&=>?@=ED@0/18<+9*,:/-8<;>?8:28=2066?F8893812+2,2(=@@88?@
-@c127e70a-405f-46c0-ae0b-e647ef99c3af
-AGTTATGAGACTGGGAGCGTTACAGAAAAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGAGTATGCAGAGGTGCTGATCGCTATTACGGAGTATCCTGCCGTGCCTATTATCCAGACTTATGGCAAGATTAAGCTTCCCGGAGAAAACTATCAAAACAGACGGTATGTTTTCACCATCCAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAAGAAAACGATCCTGACGCATCCTTCCTGTTTTCC
-+
-''+039A>BD56<@D/9>FLGHAD?47;<D9<66(*/>@@@BF=?@@?::8AB:<+-/:@:9;>1<574/.)3/-:?98IG2),(-888;CA0271=8./8////-2/430-,/0%%:-/=?IHA<,/0&('$$%()2113176')-+79>,&(%$$$'..,',')$&)&%.%%%%%%$%%##&)$''(+*()&,4587A@@@GJL;;))8719BDF</-539@B>844311:1//10)&'/00+<<C9:>6=56-.:..7/.(-@?>AKH*.
-@9a0e90b3-3c3e-4843-95cb-b1596828ed6f
-AAAGAGATGTTTTACGGGAAAACAGGAAGGATGCGTCAGGATCGTTTCAGCTCGCTGCATAGCTATGCATGAAAGCGAATGGTGATCACTTTGGGAGCTTACCTGGTGTTCATACCGTCTGTTTTCGACAGTTTCTCTCCGGGGAAGCTAATCTGCCCGCCAAGTCTACGGATAACAGGGCACGGTGATACTCCGTAACGCGATCAACACCTCCGCATACTCCCTGTCCCCGACACGCTTGCCGTCGATAAAGAGTTTTTCTGTAACACCCCCAGTCT
-+
-BE1%7>?A=FFE7-5'.25855*%5410/:48:;5371>B85@9@=<836>;A648+,2/5+&@:05E<>A><?C=$$,$%-6;92@34@@6'+-$)%--.%)$)':,=9=311@C>;DDDBB@:765638DE)63<B85*+,)*('&&$%/00/*,,%$%-.09<22/?CBD:7-(8;AB:;=BGA?;401+0&$$$#$%53->$'73;<<<?9<5=><@8=39,9<JG/$$$5F=@FC)331?D<>?IK4=5AMJPH<3+)'-.30FIGA0.701'
-@162b5056-1cc5-40d8-a1de-6bebe548bc27
-TGTTTTACCCCGGGAAGCAGGAGAGGGATGCAATCTTTGCAGGATCGTTTTCCATTTTGCCCGCTAGCTATGCATGAAAGCGATGGTGTGATCACCGGGGAGCTTACGGTGTTGTCCACCGTCTGTTTCGACAAGTTTTCTCCGGGAAGCTAATCTGCCATAAGTCTGGATAGCAGGGCACAGGTGATACCGGCAGCGATCGCTTCCTCCACGCCTCCTGTCCCCGACACGCGCCGTCGATGAAGTTTTTTCTG
-+
-%,68@8/-778/-((*),*;0/$&36882,/#$%$%)00-,6;<9?@JCDE34'())(&$''#$,,(1+?<?C:13--%--%(($&%%$'&%+%$($(1/-.454=?..1-2*$%$&'-/,+.$&##$0338**25:H?<-&8-2C8:-8542,))$)*%',+25?89;@)9%)%*+'&$'$(18=;.&&&#&,&,,.,'6%#$$'(-7;%2**+-','%5<BD@;76,**)'-(/3740*'($.49>=95*$'
-@c506ed82-9194-4814-9a9d-7532715b5f51
-AAAACTCTTTATCGACGGCAAGCGTGTCGGGGACAGGGAGTATGCCCGGAGGTGCTGATCGCTATTACGGAGTATC
-+
-(+;;<;.BDGD<BEGC<:;99/63B73@146<8,(A?</;A0+6$335;:7/578@D.&6''4--5:F9;)9B50;
-@d4db67e9-1787-4f1f-8017-f6e815022fde
-AAAGAGATGTTTTACCCCGGGAAAACAGGAAGGATGCGTCAGGATCGTTTCAGCTCGCTGCACTCAACTATGCATGAAAGCGAATGGTGATCACTTTGGGAGCTTACGGTGTTCATACCGTCTGTTTTCAGCAGTTTTCTCTCCGGGAAGCTAATCTGCCATAAGTCCTGGATAACAGGGGCACGGTGATACTCCGTAATAGCGATCAGCACCGCATAC
-+
-<8%27.857<?IA@GHA;%+8(,?8*&=9:8ED6,,5:=2:.G?<?:CC*-0').3-/7/10**+..692/10624/-,25789>4:E?>?B<=??@7=@69885'8&.=>B?C77=A?>?ABCEBID71031;15IE@F9>,@=DKJ?1@CIG<ABDFD5<;;6226@@CFDCB78:7;?BJA@AGF>>99@=B>:BC:4@?=-%8?28;.:3=87;<
-@aba91300-4618-4b54-beb5-01aefe1e0af8
-CGCTATTACGAAGGAGTATCACCGTGCCTGTTATCAGACTTATGGCAAGATTAGCTTCCGGAGAAAAAACTGTCGAAAACAGACGGTATGAACACCGTAAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTTCCCCGGGGTAAAACATCTCTTT
-+
-42@A=BA<(/%$&*#&8-)<353-B3=<>>A@*%?458331.2'+3#%)+0.*4899%+/4-///((*)'()*337731,)0,>)1420))/==5678785(10)0-12-/=977:<75&99,$%):@B;:9:(),),(8221*:;00:2144KH=A6:**0$&%4355:;?C?8:D?=<C==8<?9&+7=>@C@86@;>A??64
-@e3986483-5f5e-480a-81bc-cfaac9c8678e
-GCTATTACGAATTATCCACCGTGCCTATTATCAGACTTATGGCAGATTGGCTTTGGAGAGAAAACTGTCGAAAACCAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCTATACGGCGGAGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCGGGGTAAAACATCTCTTT
-+
-(?A@=CE-3()(49))6,69>H>::/(79,%3(0:&&%*3)-0/23-5$)**+&6;<),%:CC=5?7562**'%%61>=?:;FDF@?:4>56>?3/(<;)0*02/36<<;AAABCDFE::JIF<9;5:4<:?>@-)'3'.1$&&$&,;:00C?'4=>((,@D9H?<B<>@B<;=HG=<L(=()(&7<>@=F<;CB>D?=
-@7a97d860-e33a-4e27-b5be-c4754a2eb907
-ATTACGAAGTATCACGTGCCCTGTTATCCAGACTTATGGCAGATTAGCTTCCCGGAGAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCAAAGTGATCACCATTCGCTTTCATGCGCCTTGGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCCGAAGGGTAAAACATCTCTTT
-+
-?>A?'-$%+?'%8$03F;;;=8*57>((?3:E?E?65%,0,.,B>77?AA6<G<9C(,):0IGAD=;AEIJLC@'?3A+/68966>9?<>??:</:<-.'(%32228@;:=CGDA>78:@97424%%$'%')460((8,:;1/4////@;5;?@//5896:.+?:<ACA>@KEA@LD=C22.+01849?D<>@;A=<K5/
-@cc6e152f-3be2-4154-95c1-265c4f77a7ac
-TACGGAGTATCACCGTGCCTGTTATCCAGACTTATGGCAGATTAGCTTCCCGGAGAAAACTGCTCCAACAGACGGTATGAACACCGTAAGCTCCCAGAAGTGATCACCATTCGCTTTCTCATGCATAGCTATGCGGCGAGCTGAAAAGCTGATCCTGACGCATCCTTCCTGTTTTTCCCGGGAGTAAAACATCTCTTT
-+
-,*635,44()6,87.6'66=(@;0**E=DFCL?77-56732,/(-./1-.//17&(5EE;:)')(6,,4=8>C29;5>8832,>>459;+;;)-(+$%$*77;6CAABDB?-0*+,(&$+&**8:85=??@))?%.7+*4/+(*.'($#%,,++4;EBB:B>78=8<=@GBDCGB@5;A+1<$6:EGDAG;:>>@@?H
-@749ba682-4ec2-4367-8bb3-51878f06992d
-CCGGGAAAGCGGAAGGATCGTCAGGATCGTTGCTACAGCTCTGCTACATATGCATGAAAGCGAATGGTGATGCTTTGGGACTTTACGGTGTTTCATACCGTCTGTTTTCGACAGTTTTCTCTCCAGGGAAACTAATCTGCCAGCAAGTCTGGATAACAGGG
-+
-#$$(+('&%,$)5;:8/&(,121165++.-/$$(%)(%#%'#$$$$&&%$%(3/1<222(666:=8<47/&$&)),&'&',-/.39=B>B?=-89;=>=;;;335686E;=9499=PA@-8<%/'/*+,)$77=7/-5//.-&(()**7',./102,&,&'
-@3d6bdcab-ef5c-4ff8-a928-23066fb4e887
-CTGTTATCAGACTTATGGCAGATTAGCTTCCCGGAGAAGAAAACTGTCGAAAACAGACGGTATGAACACCGTAAGCTCCCAAAAGTGATCACCATTCATCATGCATAGCTATGCGGGCAGACTGCGAAAACGATCCTGACTCCTTCCTGTTTTCCGGGGTAAAACATCTCTTT
-+
-12551)$>,,/,,,AE??>==?6/.'''-8>B03<+,,-=CA@<A@<A98=<17581:*0<BC66@AA<>;;/09:6470999-%171+98==8<;6#'36;AC;7:689<<89%*./(&$++$-+--<-;=>55:4;*%&%*%/454@CAHA/318?G?4599=9?DEA@?E
-@0b41ea60-ea37-43ef-a912-260c4d33a356
-CTGTTATCCAGACTTATGGCAGATTAGCTTCCGGAGAAAACTGCTTCGAAAAACAGACGGTATGAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTCATGCATAGCGCTATGCAGCGAGCTGAAAACGATCTGACGCATCCTTCCTGTTTTCCCGGGGTAAAACATCTCTTT
-+
-=B>B3+++7-2-))%&.%,3**749689:=1B0.3&)(-'$$%#%(*(((('$,)+(/+,,/48:>;62+7:)*.<;9>@DE75@?<?GFGD@DDA$$=>;>?::>-043+).2?;<(&551.;><:8G@6E@<6@7<6@1CE78BDB>?=?57I@'-G3;@B=>@F@?8<?>794-
-@cd8d2944-a807-434b-92d5-bfa925697c85
-GTTATCCAGACTTATGGCAGATTAGCTTCCCGGAGAGAAAACTGGCATGAAAACAGACAGGTATGAACACCGTAAACTCGGTGATCACCATTCGCTTTCATGCATAGCTATGCAGCGAGCTGAAAACGATCCTGACGCATCTCCTTCCTGTTTTCCGGGGTAAAACATCTCTTT
-+
-8?>>%%06/B@FEFG7=854742')9<=+3B9:<98%;<>3..-(&$*/13,*;8;1+&59ADB55<94<<:;99(&)+#&62-'('668:7855;=C><24B=>==>;B<:30=;=1;9575IF9A=E55<:@?GC;77=069<=25152/56)/,45?>@BE162;>:9DCE
-@a492dd23-2c03-4d9b-a606-dee7268bd4fa
-AAAGAGATGTTTTTGCGGAAAACAGGAAGGATGCGTCAGGATCGTTTTCAGCGCTATAGCTATGCATGAAAGCGAATGGTGATCCTTTGGGAGCTTACGGTGTTCATGCCAATCTGTTTTCGACAGTTTCTCTCCGAGGAAGCTAATCTGCCGCAAGTCTAGTTAAC
-+
-F:&-/77;:@??=8%%$(#'+()%+9.99AB?==<<7/;;4/;;B>?-+(*2%%&0-1-=5;99GD=88>9>??=IC2:B?:%%*#*-&.1**,--;A::8BID?4&&%8'(<AE3??;C@>B64>:;31&*,(5('7A04.>@CC;AA7%1-1%&-/5'%*%-+,/
-@4a58265a-1d25-47a1-b851-e7687203734f
-GGGAAACCCAGGAGGATCGTCAGGATCGTTTTTTCAGCTCGCTGCTATGTATGCGCTGAAAGCGAATGGTGATCACTTTGGGGAGCTTACGGTGTTCATACTGTCTGTTTTCGACAGTTTTCTCTCCGGGAAGCTAATCTGCCATAAGTCTGGATAAC
-+
-)**%&&%5'%)*$..5%$$,70?B?:>?GBLB<0))%&'-78>.11/$$+($&$&%***2),=88=@,1A=:3<25;<959E;.9?BB*A<CCHBBB==BCC>=B>B9?LL;AA74C>CNEDF<C%?7<D78.=>C=4=?@BB9@>>2-A14:C;..5
-@f9a56724-1fa4-4807-bacc-f0a85587afd7
-GAACACCGTAAGCTCCCAAAGTGATCACCATTCGCTTTTTCATGCATAGCTATGCAGCGACTGGCGATCCTGACGCATCTTCTGTTTTCC
-+
-414===BA;3-.21$+&')'%-20-,((+6:57(*+,139@@?A534546/24022**)$$$#&(--++-7<+6*.*(())(,-03<:(,
-@e525f31a-e4d6-4fe6-a703-7038efa2f178
-GCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTCCCGGGTAAAACATCTCTTT
-+
-;B@E::0+5511=2122@>52((''*<G=E:?A45:79$=JFCC?AJG*024<>HECB@C@?KHI
-@eeef3ccf-2188-4382-8399-a9442bbbf40a
-GCTATGCAGCGAGCTGAAAACGATCCTGACGCATCCTTCCTGTTTTCCCGGGGTAAAACATCTCTTT
-+
-@=:3335937))43378KC?<?A<>CKMEH?BC55=4C>?KDFCLC4@G363877800+7<=;3;;>
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/bwa-mem-mt-genome.fa.fai	Tue Sep 01 03:08:24 2020 -0400
@@ -0,0 +1,1 @@
+gi|251831106|ref|NC_012920.1|	16569	31	70	71
Binary file test-data/medaka_test.bam has changed
Binary file test-data/medaka_test.bam.bai has changed
Binary file test-data/medaka_test.hdf has changed
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/ref.fasta	Tue Sep 01 03:08:24 2020 -0400
@@ -0,0 +1,2 @@
+>NC_045512.2
+ATTAAAGGTTTATACCTTCCCAGGTAACAAACCAACCAACTTTCGATCTCTTGTAGATCTGTTCTCTAAACGAACTTTAAAATCTGTGTGGCTGTCACTCGGCTGCATGCTTAGTGCACTCACGCAGTATAATTAATAACTAATTACTGTCGTTGACAGGACACGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCAGCACATCTAGGTTTCGTCCGGGTGTGACCGAAAGGTAAGATGGAGAGCCTTGTCCCTGGTTTCAACGAGAAAACACACGTCCAACTCAGTTTGCCTGTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTTTGGAGACTCCGTGGAGGAGGTCTTATCAGAGGCACGTCAACATCTTAAAGATGGCACTTGTGGCTTAGTAGAAGTTGAAAAAGGCGTTTTGCCTCAACTTGAACAGCCCTATGTGTTCATCAAACGTTCGGATGCTCGAACTGCACCTCATGGTCATGTTATGGTTGAGCTGGTAGCAGAACTCGAAGGCATTCAGTACGGTCGTAGTGGTGAGACACTTGGTGTCCTTGTCCCTCATGTGGGCGAAATACCAGTGGCTTACCGCAAGGTTCTTCTTCGTAAGAACGGTAATAAAGGAGCTGGTGGCCATAGTTACGGCGCCGATCTAAAGTCATTTGACTTAGGCGACGAGCTTGGCACTGATCCTTATGAAGATTTTCAAGAAAACTGGAACACTAAACATAGCAGTGGTGTTACCCGTGAACTCATGCGTGAGCTTAACGGAGGGGCATACACTCGCTATGTCGATAACAACTTCTGTGGCCCTGATGGCTACCCTCTTGAGTGCATTAAAGACCTTCTAGCACGTGCTGGTAAAGCTTCATGCACTTTGTCCGAACAACTGGACTTTATTGACACTAAGAGGGGTGTATACTGCTGCCGTGAACATGAGCATGAAATTGCTTGGTACACGGAACGTTCTGAAAAGAGCTATGAATTGCAGACACCTTTTGAAATTAAATTGGCAAAGAAATTTGACACCTTCAATGGGGAATGTCCAAATTTTGTATTTCCCTTAAATTCCATAATCAAGACTATTCAACCAAGGGTTGAAAAGAAAAAGCTTGATGGCTTTATGGGTAGAATTCGATCTGTCTATCCAGTTGCGTCACCAAATGAATGCAACCAAATGTGCCTTTCAACTCTCATGAAGTGTGATCATTGTGGTGAAACTTCATGGCAGACGGGCGATTTTGTTAAAGCCACTTGCGAATTTTGTGGCACTGAGAATTTGACTAAAGAAGGTGCCACTACTTGTGGTTACTTACCCCAAAATGCTGTTGTTAAAATTTATTGTCCAGCATGTCACAATTCAGAAGTAGGACCTGAGCATAGTCTTGCCGAATACCATAATGAATCTGGCTTGAAAACCATTCTTCGTAAGGGTGGTCGCACTATTGCCTTTGGAGGCTGTGTGTTCTCTTATGTTGGTTGCCATAACAAGTGTGCCTATTGGGTTCCACGTGCTAGCGCTAACATAGGTTGTAACCATACAGGTGTTGTTGGAGAAGGTTCCGAAGGTCTTAATGACAACCTTCTTGAAATACTCCAAAAAGAGAAAGTCAACATCAATATTGTTGGTGACTTTAAACTTAATGAAGAGATCGCCATTATTTTGGCATCTTTTTCTGCTTCCACAAGTGCTTTTGTGGAAACTGTGAAAGGTTTGGATTATAAAGCATTCAAACAAATTGTTGAATCCTGTGGTAATTTTAAAGTTACAAAAGGAAAAGCTAAAAAAGGTGCCTGGAATATTGGTGAACAGAAATCAATACTGAGTCCTCTTTATGCATTTGCATCAGAGGCTGCTCGTGTTGTACGATCAATTTTCTCCCGCACTCTTGAAACTGCTCAAAATTCTGTGCGTGTTTTACAGAAGGCCGCTATAACAATACTAGATGGAATTTCACAGTATTCACTGAGACTCATTGATGCTATGATGTTCACATCTGATTTGGCTACTAACAATCTAGTTGTAATGGCCTACATTACAGGTGGTGTTGTTCAGTTGACTTCGCAGTGGCTAACTAACATCTTTGGCACTGTTTATGAAAAACTCAAACCCGTCCTTGATTGGCTTGAAGAGAAGTTTAAGGAAGGTGTAGAGTTTCTTAGAGACGGTTGGGAAATTGTTAAATTTATCTCAACCTGTGCTTGTGAAATTGTCGGTGGACAAATTGTCACCTGTGCAAAGGAAATTAAGGAGAGTGTTCAGACATTCTTTAAGCTTGTAAATAAATTTTTGGCTTTGTGTGCTGACTCTATCATTATTGGTGGAGCTAAACTTAAAGCCTTGAATTTAGGTGAAACATTTGTCACGCACTCAAAGGGATTGTACAGAAAGTGTGTTAAATCCAGAGAAGAAACTGGCCTACTCATGCCTCTAAAAGCCCCAAAAGAAATTATCTTCTTAGAGGGAGAAACACTTCCCACAGAAGTGTTAACAGAGGAAGTTGTCTTGAAAACTGGTGATTTACAACCATTAGAACAACCTACTAGTGAAGCTGTTGAAGCTCCATTGGTTGGTACACCAGTTTGTATTAACGGGCTTATGTTGCTCGAAATCAAAGACACAGAAAAGTACTGTGCCCTTGCACCTAATATGATGGTAACAAACAATACCTTCACACTCAAAGGCGGTGCACCAACAAAGGTTACTTTTGGTGATGACACTGTGATAGAAGTGCAAGGTTACAAGAGTGTGAATATCACTTTTGAACTTGATGAAAGGATTGATAAAGTACTTAATGAGAAGTGCTCTGCCTATACAGTTGAACTCGGTACAGAAGTAAATGAGTTCGCCTGTGTTGTGGCAGATGCTGTCATAAAAACTTTGCAACCAGTATCTGAATTACTTACACC
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/ref.fasta.fai	Tue Sep 01 03:08:24 2020 -0400
@@ -0,0 +1,1 @@
+NC_045512.2	2940	13	2940	2941
Binary file test-data/variants.vcf.gz has changed
--- a/variant.xml	Thu Jun 18 05:08:21 2020 -0400
+++ b/variant.xml	Tue Sep 01 03:08:24 2020 -0400
@@ -1,5 +1,5 @@
 <?xml version="1.0"?>
-<tool id="medaka_variant" name="medaka: Variant" version="@TOOL_VERSION@+galaxy0" profile="@PROFILE@">
+<tool id="medaka_variant" name="medaka: Variant" version="@TOOL_VERSION@+galaxy1" profile="@PROFILE@">
     <description>Probability decoding</description>
     <macros>
         <import>macros.xml</import>
@@ -25,62 +25,80 @@
 #end for
 '$out_result' ## output
 
-|& tee '$out_log'
+2>&1 | tee '$out_log'
+
+#if $out_annotated
+    && python '$__tool_directory__/annotateVCF.py' '$out_result' '$in_mpileup' '$out_annotated'
+#end if
     ]]></command>
     <inputs>
         <param argument="inputs" type="data" format="h5" multiple="true" label="Select consensus file(s)"/>
         <expand macro="reference"/>
-        <param argument="--region" type="text" value="" optional="true" label="Set reference names to limit variant calling" help="Separated by ','."/>
+        <param argument="--region" type="text" value="" optional="true" label="Set reference names to limit variant calling" help="Separated by ','.">
+            <sanitizer invalid_char="">
+                <valid initial="string.ascii_letters,string.digits">
+                    <add value="_"/>
+                    <add value=","/>
+                    <add value="."/>
+                </valid>
+            </sanitizer>
+        </param>
         <param argument="--verbose" type="boolean" truevalue="--verbose" falsevalue="" label="Populate VCF info fields?"/>
-        <param name="out" type="select" multiple="true" optional="false" label="Select output file(s)">
-            <option value="result" selected="true">Result</option>
-            <option value="log">Log</option>
-        </param>
+
+        <conditional name="output_annotated">
+            <param name="output_annotated_select" type="select" label="Output annotated VCF?" help="Annotate allele frequency, depth of coverage, etc for each variant (requires pileup file)">
+                <option value="true" selected="true">Output annotated VCF</option>
+                <option value="false">Don't output annotated VCF</option>
+            </param>
+            <when value="true">
+                <param name="in_mpileup" type = "data" format="pileup" optional="false" label="Mpileup to annotate the VCF"/>
+            </when>
+        </conditional>
+        <param name="output_log_bool" type="boolean" label="Output log file?" checked="true"/>
     </inputs>
     <outputs>
         <!-- standard -->
-        <data name="out_result" format="vcf" label="${tool.name} on ${on_string}: Result">
-            <filter>'result' in out</filter>
+        <data name="out_result" format="vcf" label="${tool.name} on ${on_string}: Result"/>
+        <!-- optional -->
+        <data name="out_annotated" format="vcf" label="${tool.name} on ${on_string}: Annotated">
+            <filter>output_annotated_select</filter>
         </data>
-        <!-- optional -->
         <data name="out_log" format="tabular" label="${tool.name} on ${on_string}: Log">
-            <filter>'log' in out</filter>
+            <filter>output_log_bool</filter>
         </data>
     </outputs>
     <tests>
         <!-- #1 default -->
-        <test expect_num_outputs="1">
+        <test expect_num_outputs="3">
+            <param name="inputs" value="medaka_test.hdf"/>
             <conditional name="reference_source">
-                <param name="reference_source_selector" value="cached"/>
-                <param name="ref_file" value="bwa-mem-mt-genome"/>
+                <param name="reference_source_selector" value="history"/>
+                <param name="ref_file" value="ref.fasta"/>
             </conditional>
-            <param name="inputs" value="consensus.hdf"/>
+            <conditional name="output_annotated">
+                <param name="output_annotated_select" value="true"/>
+                <param name="in_mpileup" value="annotate_vcf_test.pileup"/>
+            </conditional>
+            <param name="output_log_bool" value="true"/>
+            
             <output name="out_result">
                 <assert_contents>
-                    <has_n_lines n="6"/>
-                    <has_line line="##fileformat=VCFv4.1"/>
+                    <has_n_lines n="9"/>
+                    <has_line line="##fileformat=VCFv4.1" />
+                    <has_line line="##medaka_version=1.0.3" />
                 </assert_contents>
             </output>
-        </test>
-        <!-- #2 -->
-        <test expect_num_outputs="2">
-            <conditional name="reference_source">
-                <param name="reference_source_selector" value="cached"/>
-                <param name="ref_file" value="bwa-mem-mt-genome"/>
-            </conditional>
-            <param name="inputs" value="consensus.hdf"/>
-            <param name="verbose" value="true"/>
-            <param name="out" value="result,log"/>
-            <output name="out_result">
+            <output name="out_annotated">
                 <assert_contents>
-                    <has_n_lines n="13"/>
-                    <has_line line="##fileformat=VCFv4.1"/>
+                    <has_n_lines n="16"/>
+                    <has_line line="##fileformat=VCFv4.1" />
+                    <has_line line="##medaka_version=1.0.3" />
+                    <has_line line="##annotateVCFVersion=0.1" />
                 </assert_contents>
             </output>
             <output name="out_log">
                 <assert_contents>
-                    <has_n_lines n="17"/>
-                    <has_text_matching expression=".+Loaded.+"/>
+                    <has_n_lines n="8" />
                 </assert_contents>
             </output>
         </test>
@@ -108,4 +126,4 @@
 @REFERENCES@
     ]]></help>
     <expand macro="citations"/>
-</tool>
\ No newline at end of file
+</tool>