changeset 1:500832f27cbc draft

Uploaded
author iuc
date Thu, 22 Jan 2015 08:28:37 -0500 (2015-01-22)
parents e8adfc4c0a6b
children e09ce114d240
files .shed.yml data_manager/data_manager_snpEff_databases.py data_manager/data_manager_snpEff_databases.xml data_manager/data_manager_snpEff_download.py data_manager/data_manager_snpEff_download.xml data_manager_conf.xml datatypes_conf.xml lib/galaxy/datatypes/snpeff.py lib/galaxy/datatypes/snpeff.pyc readme.rst repository_dependencies.xml snpEff.xml snpEff_databases.xml snpEff_download.xml snpEff_macros.xml snpSift_annotate.xml snpSift_caseControl.xml snpSift_filter.xml snpSift_int.xml test-data/annotate_1.vcf test-data/annotate_5.vcf test-data/db_test_1.vcf test-data/interval.bed test-data/test.private.01.vcf test-data/test.private.02.vcf test-data/test01.vcf tool-data/snpeff_annotations.loc.sample tool-data/snpeff_databases.loc.sample tool-data/snpeff_genomedb.loc.sample tool-data/snpeff_regulationdb.loc.sample tool-data/snpeffv_annotations.loc.sample tool-data/snpeffv_databases.loc.sample tool-data/snpeffv_genomedb.loc.sample tool-data/snpeffv_regulationdb.loc.sample tool_data_table_conf.xml.sample tool_dependencies.xml
diffstat 36 files changed, 196 insertions(+), 1940 deletions(-) [+]
line wrap: on
line diff
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/.shed.yml	Thu Jan 22 08:28:37 2015 -0500
@@ -0,0 +1,3 @@
+# repository published to https://toolshed.g2.bx.psu.edu/repos/iuc/snpeff
+owner: iuc
+name: snpeff
--- a/data_manager/data_manager_snpEff_databases.py	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,82 +0,0 @@
-#!/usr/bin/env python
-
-import sys
-import os
-import re
-import tempfile
-import subprocess
-import fileinput
-import shutil
-import optparse
-import urllib2
-from ftplib import FTP
-import tarfile
-
-from galaxy.util.json import from_json_string, to_json_string
-
-def stop_err(msg):
-    sys.stderr.write(msg)
-    sys.exit(1)
-
-def fetch_databases(data_manager_dict, target_directory, jar_path):
-    (snpEff_dir,snpEff_jar) = os.path.split(jar_path)
-    if not os.path.exists(target_directory):
-        os.makedirs(target_directory)
-    databases_path = os.path.join( target_directory, 'databases.out' )
-    databases_output = open(databases_path,'w')
-    args = [ 'java','-jar', ]
-    args.append( snpEff_jar )
-    args.append( 'databases' )
-    # tmp_stderr = tempfile.NamedTemporaryFile( prefix = "tmp-data-manager-snpEff-stderr" )
-    # databases_output = open(databases_path)
-    # proc = subprocess.Popen( args=args, shell=False, cwd=snpEff_dir, stdout=databases_output.fileno(), stderr=tmp_stderr.fileno() )
-    proc = subprocess.Popen( args=args, shell=False, cwd=snpEff_dir, stdout=databases_output.fileno() )
-    return_code = proc.wait()
-    if return_code:
-        sys.exit( return_code )
-    databases_output.close()
-    try:
-        data_manager_dict['data_tables'] = data_manager_dict.get( 'data_tables', {} )
-        data_manager_dict['data_tables']['snpeff_databases'] = data_manager_dict['data_tables'].get( 'snpeff_databases', [] )
-        data_table_entries = []
-        fh = open(databases_path,'r')
-        for i,line in enumerate(fh):
-            fields = line.split('\t')
-            if len(fields) >= 2:
-                genome_version = fields[0].strip()
-                if genome_version.startswith("Genome") or genome_version.startswith("-"):
-                    continue
-                #snpeff test genome
-                if genome_version == '30c2c903' or fields[1].strip() == 'TestCase' or fields[1].strip().startswith('Test_'):
-                    continue
-                description = fields[1].strip() + ' : ' + genome_version
-                data_table_entries.append(dict(value=genome_version, name=description))
-        data_manager_dict['data_tables']['snpeff_databases'] = data_table_entries
-    except Exception, e:
-        stop_err( 'Error parsing %s %s\n' % (config,str( e )) )
-    else:
-        fh.close()
-    return data_manager_dict
-
-def main():
-    #Parse Command Line
-    parser = optparse.OptionParser()
-    parser.add_option( '-j', '--jar_path', dest='jar_path', action='store', type="string", default=None, help='snpEff.jar path' )
-    (options, args) = parser.parse_args()
-
-    filename = args[0]
-
-    params = from_json_string( open( filename ).read() )
-    target_directory = params[ 'output_data' ][0]['extra_files_path']
-    os.mkdir( target_directory )
-    data_manager_dict = {}
-
-
-    #Create Defuse Reference Data
-    data_manager_dict = fetch_databases( data_manager_dict, target_directory, options.jar_path)
-
-    #save info to json file
-    open( filename, 'wb' ).write( to_json_string( data_manager_dict ) )
-
-if __name__ == "__main__": main()
-
--- a/data_manager/data_manager_snpEff_databases.xml	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,41 +0,0 @@
-<tool id="data_manager_snpeff_databases" name="SnpEff Databases" version="3.4" tool_type="manage_data">
-	<description>Read the list of available snpEff databases</description>
-	<requirements>
-		<requirement type="package" version="3.4">snpEff</requirement>
-	</requirements>
-	<command interpreter="python">
-        data_manager_snpEff_databases.py --jar_path \$SNPEFF_JAR_PATH/snpEff.jar "$out_file"
-        </command>
-	<inputs>
-	</inputs>
-	<outputs>
-           <data name="out_file" format="data_manager_json"/>
-	</outputs>
-        <stdio>
-          <exit_code range=":-1"  level="fatal"   description="Error: Cannot open file" />
-          <exit_code range="1:"  level="fatal"   description="Error" />
-        </stdio>
-        <tests>
-            <test>
-                <output name="out_file">
-                    <assert_contents>
-                        <!-- Check that a genome was added -->
-                        <has_text text="GRCh37.72" />
-                    </assert_contents>
-                </output>
-            </test>
-        </tests>
-	<help>
-
-This tool updatess the list of SnpEff databases for the SnpEff Download data manager.
-It should only need to be run once for a snpEff version, 
-since it populates the SnpEff Download data manager from the snpEff config file.
-
-For information about snpEff:    http://snpEff.sourceforge.net
-
-Please cite:
-"A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3.", Cingolani P, Platts A, Wang le L, Coon M, Nguyen T, Wang L, Land SJ, Lu X, Ruden DM. Fly (Austin). 2012 Apr-Jun;6(2):80-92. PMID: 22728672 [PubMed - in process]
-
-	</help>
-</tool>
-
--- a/data_manager/data_manager_snpEff_download.py	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,114 +0,0 @@
-#!/usr/bin/env python
-
-import sys
-import os
-import re
-import tempfile
-import subprocess
-import fileinput
-import shutil
-import optparse
-import urllib2
-from ftplib import FTP
-import tarfile
-
-from galaxy.util.json import from_json_string, to_json_string
-
-def stop_err(msg):
-    sys.stderr.write(msg)
-    sys.exit(1)
-
-"""
-# Download human database 'hg19'
-java -jar snpEff.jar download -v hg19
-
-        <command>java -jar \$SNPEFF_JAR_PATH/snpEff.jar download -c \$JAVA_JAR_PATH/snpEff.config $genomeVersion > $logfile </command>
-
-snpEffectPredictor.bin
-regulation_HeLa-S3.bin
-regulation_pattern = 'regulation_(.+).bin'
-
-
-"""
-def download_database(data_manager_dict, target_directory, jar_path,config,genome_version,organism):
-    ## get data_dir from config 
-    ##---
-    ## Databases are stored here
-    ## E.g.: Information for 'hg19' is stored in data_dir/hg19/
-    ##
-    ## Note: Since version 2.1 you can use tilde ('~') as first character to refer to your home directory
-    ##---
-    #data_dir = ~/snpEff/data/
-    data_dir = target_directory
-    (snpEff_dir,snpEff_jar) = os.path.split(jar_path)
-    args = [ 'java','-jar' ]
-    args.append( jar_path )
-    args.append( 'download' )
-    args.append( '-c' )
-    args.append( config )
-    args.append( '-dataDir' )
-    args.append( data_dir )
-    args.append( '-v' )
-    args.append( genome_version )
-    proc = subprocess.Popen( args=args, shell=False, cwd=snpEff_dir )
-    return_code = proc.wait()
-    if return_code:
-        sys.exit( return_code )
-    ## search data_dir/genome_version for files
-    regulation_pattern = 'regulation_(.+).bin'
-    #  annotation files that are included in snpEff by a flag
-    annotations_dict = {'nextProt.bin' : '-nextprot','motif.bin': '-motif'}
-    genome_path = os.path.join(data_dir,genome_version)
-    if os.path.isdir(genome_path):
-        for root, dirs, files in os.walk(genome_path):
-            for fname in files:
-                if fname.startswith('snpEffectPredictor'):
-                    # if snpEffectPredictor.bin download succeeded
-                    name = genome_version + (' : ' + organism if organism else '') 
-                    data_table_entry = dict(value=genome_version, name=name, path=data_dir)
-                    _add_data_table_entry( data_manager_dict, 'snpeff_genomedb', data_table_entry )
-                else:
-                    m = re.match(regulation_pattern,fname)
-                    if m:
-                        name = m.groups()[0]
-                        data_table_entry = dict(genome=genome_version,value=name, name=name)
-                        _add_data_table_entry( data_manager_dict, 'snpeff_regulationdb', data_table_entry )
-                    elif fname in annotations_dict:
-                        value = annotations_dict[fname]
-                        name = value.lstrip('-')
-                        data_table_entry = dict(genome=genome_version,value=value, name=name)
-                        _add_data_table_entry( data_manager_dict, 'snpeff_annotations', data_table_entry )
-    return data_manager_dict
-
-def _add_data_table_entry( data_manager_dict, data_table, data_table_entry ):
-    data_manager_dict['data_tables'] = data_manager_dict.get( 'data_tables', {} )
-    data_manager_dict['data_tables'][data_table] = data_manager_dict['data_tables'].get( data_table, [] )
-    data_manager_dict['data_tables'][data_table].append( data_table_entry )
-    return data_manager_dict
-
-def main():
-    #Parse Command Line
-    parser = optparse.OptionParser()
-    parser.add_option( '-j', '--jar_path', dest='jar_path', action='store', type="string", default=None, help='snpEff.jar path' )
-    parser.add_option( '-c', '--config', dest='config', action='store', type="string", default=None, help='snpEff.config path' )
-    parser.add_option( '-g', '--genome_version', dest='genome_version', action='store', type="string", default=None, help='genome_version' )
-    parser.add_option( '-o', '--organism', dest='organism', action='store', type="string", default=None, help='organism name' )
-    (options, args) = parser.parse_args()
-
-    filename = args[0]
-
-    params = from_json_string( open( filename ).read() )
-    target_directory = params[ 'output_data' ][0]['extra_files_path']
-    os.mkdir( target_directory )
-    data_manager_dict = {}
-
-
-    #Create SnpEff Reference Data
-    for genome_version, organism in zip(options.genome_version.split(','), options.organism.split(',')):
-        download_database( data_manager_dict, target_directory, options.jar_path, options.config, genome_version, organism )
-
-    #save info to json file
-    open( filename, 'wb' ).write( to_json_string( data_manager_dict ) )
-
-if __name__ == "__main__": main()
-
--- a/data_manager/data_manager_snpEff_download.xml	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,51 +0,0 @@
-<tool id="data_manager_snpeff_download" name="SnpEff Download" version="3.4" tool_type="manage_data">
-    <description>Download a new database</description>
-    <requirements>
-        <requirement type="package" version="3.4">snpEff</requirement>
-    </requirements>
-    <command interpreter="python">
-        data_manager_snpEff_download.py --jar_path \$SNPEFF_JAR_PATH/snpEff.jar --config \$SNPEFF_JAR_PATH/snpEff.config 
-        --genome_version "${genome_databases.fields.value}"
-        --organism "${genome_databases.fields.name}"
-        "$out_file"
-        </command>
-    <inputs>
-        <param name="genome_databases" type="select" display="checkboxes" multiple="true" label="Genome Version">
-            <options from_data_table="snpeff_databases">
-                <filter type="sort_by" column="0" />
-            </options>
-        </param>
-    </inputs>
-
-    <outputs>
-           <data name="out_file" format="data_manager_json" label="${tool.name} : ${genome_databases.fields.value}"/>
-    </outputs>
-    <stdio>
-        <exit_code range=":-1"  level="fatal"   description="Error: Cannot open file" />
-        <exit_code range="1:"  level="fatal"   description="Error" />
-    </stdio>
-    <tests>
-        <test>
-            <param name="genome_databases" value="GRCh37.71"/>
-            <output name="out_file">
-                <assert_contents>
-                    <!-- Check that a genome was added -->
-                    <has_text text="GRCh37.71" />
-                    <has_text text="snpeff_regulationdb" />
-                    <has_text text="snpeff_annotations" />
-                </assert_contents>
-            </output>
-        </test>
-    </tests>
-    <help>
-
-This tool downloads a SnpEff database.
-
-For details about this tool, please go to http://snpEff.sourceforge.net
-
-Please cite:
-"A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3.", Cingolani P, Platts A, Wang le L, Coon M, Nguyen T, Wang L, Land SJ, Lu X, Ruden DM. Fly (Austin). 2012 Apr-Jun;6(2):80-92. PMID: 22728672 [PubMed - in process]
-
-    </help>
-</tool>
-
--- a/data_manager_conf.xml	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,42 +0,0 @@
-<?xml version="1.0"?>
-<data_managers>
-  <data_manager tool_file="data_manager/data_manager_snpEff_databases.xml" id="data_manager_snpeff_databases" >
-    <data_table name="snpeff_databases">  <!-- Defines a Data Table to be modified. -->
-      <output> <!-- Handle the output of the Data Manager Tool -->
-        <column name="value" /> <!-- columns that are going to be specified by the Data Manager Tool -->
-        <column name="name" /> <!-- columns that are going to be specified by the Data Manager Tool -->
-      </output>
-    </data_table>
-  </data_manager>
-  <data_manager tool_file="data_manager/data_manager_snpEff_download.xml" id="data_manager_snpeff_download" >
-    <data_table name="snpeff_genomedb">  <!-- Defines a Data Table to be modified. -->
-      <output> <!-- Handle the output of the Data Manager Tool -->
-        <column name="value" /> <!-- columns that are going to be specified by the Data Manager Tool -->
-        <column name="name" />  <!-- columns that are going to be specified by the Data Manager Tool -->
-        <column name="path" output_ref="out_file" >
-          <move type="directory" relativize_symlinks="True">
-            <target base="${GALAXY_DATA_MANAGER_DATA_PATH}">snpEff/data</target>
-          </move>
-          <value_translation>${GALAXY_DATA_MANAGER_DATA_PATH}/snpEff/data</value_translation>
-          <value_translation type="function">abspath</value_translation>
-        </column>
-      </output>
-    </data_table>
-    <data_table name="snpeff_regulationdb">  <!-- Defines a Data Table to be modified. -->
-      <output> <!-- Handle the output of the Data Manager Tool -->
-        <column name="genome" /> <!-- columns that are going to be specified by the Data Manager Tool -->
-        <column name="value" /> <!-- columns that are going to be specified by the Data Manager Tool -->
-        <column name="name" />  <!-- columns that are going to be specified by the Data Manager Tool -->
-      </output>
-    </data_table>
-    <data_table name="snpeff_annotations">  <!-- Defines a Data Table to be modified. -->
-      <output> <!-- Handle the output of the Data Manager Tool -->
-        <column name="genome" /> <!-- columns that are going to be specified by the Data Manager Tool -->
-        <column name="value" /> <!-- columns that are going to be specified by the Data Manager Tool -->
-        <column name="name" />  <!-- columns that are going to be specified by the Data Manager Tool -->
-      </output>
-    </data_table>
-  </data_manager>
-</data_managers>
-
-
--- a/datatypes_conf.xml	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,10 +0,0 @@
-<?xml version="1.0"?>
-<datatypes>
-    <datatype_files>
-        <datatype_file name="snpeff.py"/>
-    </datatype_files>
-    <registration>
-        <datatype extension="snpeffdb" type="galaxy.datatypes.snpeff:SnpEffDb" display_in_upload="True"/>
-    </registration>
-</datatypes>
-
--- a/lib/galaxy/datatypes/snpeff.py	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,46 +0,0 @@
-"""
-SnpEff datatypes
-"""
-import os,os.path,re,sys
-import galaxy.datatypes.data
-from galaxy.datatypes.data import Text
-from galaxy.datatypes.metadata import MetadataElement
-
-class SnpEffDb( Text ):
-    """Class describing an IGV tiled data file (TDF) .tdf  binary file"""
-    file_ext = "snpeffdb"
-    MetadataElement( name="genome_version", default=None, desc="Genome Version", readonly=True, visible=True, no_value=None )
-    MetadataElement( name="regulation", default=[], desc="Regulation Names", readonly=True, visible=True, no_value=[] )
-    MetadataElement( name="annotation", default=[], desc="Annotation Names", readonly=True, visible=True, no_value=[] )
-
-    def __init__( self, **kwd ):
-        Text.__init__( self, **kwd )
-
-    def set_meta( self, dataset, **kwd ):
-        Text.set_meta(self, dataset, **kwd )
-        data_dir = dataset.extra_files_path
-        ## search data_dir/genome_version for files
-        regulation_pattern = 'regulation_(.+).bin'
-        #  annotation files that are included in snpEff by a flag
-        annotations_dict = {'nextProt.bin' : '-nextprot','motif.bin': '-motif'}
-        regulations = []
-        annotations = []
-        if data_dir and os.path.isdir(data_dir):
-            for root, dirs, files in os.walk(data_dir):
-                for fname in files:
-                    if fname.startswith('snpEffectPredictor'):
-                        # if snpEffectPredictor.bin download succeeded
-                        genome_version = os.path.basename(root)
-                        dataset.metadata.genome_version = genome_version
-                    else:
-                        m = re.match(regulation_pattern,fname)
-                        if m:
-                            name = m.groups()[0]
-                            regulations.append(name)
-                        elif fname in annotations_dict:
-                            value = annotations_dict[fname]
-                            name = value.lstrip('-')
-                            annotations.append(name)
-            dataset.metadata.regulation = regulations
-            dataset.metadata.annotation = annotations
-
Binary file lib/galaxy/datatypes/snpeff.pyc has changed
--- a/readme.rst	Wed Dec 11 08:53:32 2013 -0500
+++ b/readme.rst	Thu Jan 22 08:28:37 2015 -0500
@@ -1,24 +1,38 @@
-These are galaxy tools for SnpEff a variant annotation and effect prediction tool by Pablo Cingolani. 
+SnpEff wrappers
+===============
+
+These are galaxy tools for SnpEff_, a variant annotation and effect prediction tool by Pablo Cingolani.
 It annotates and predicts the effects of variants on genes (such as amino acid changes).
-( http://snpeff.sourceforge.net/ )
+
+.. _SnpEff: http://snpeff.sourceforge.net/
+
 
-This repository contains a tool_dependencies.xml file that will attempt to automatically install SnpEff and SnpSift.   
+This repository let you automatically install SnpEff and SnpSift.
+This will use the default location for genome reference downloads from the ``snpEff.config`` file:
+
+  data_dir = ~/snpEff/data/
 
-This will use the default location for genome reference downloads from the snpEff.config:
-data_dir = ~/snpEff/data/
-You can manually edit the installed snpEff.config and change the location, or you can create a symbolic link to the desired data location from ~/snpEff.
+You can manually edit the installed ``snpEff.config`` file and change the location, or you can create a symbolic link to the desired data location from ``~/snpEff``.
+
+The genome reference options used by the tools "SnpEff" (snpEff.xml) and "SnpEff Download" (snpEff_download.xml) are taken from the ``tool-data/snpeffect_genomedb.loc`` file.
+You can fill this file by running the following command:
 
-The genome reference options used by the tools:
-    "SnpEff"  snpEff.xml
-    "SnpEff Download" snpEff_download.xml
-are taken from: tool-data/snpeffect_genomedb.loc
+  java -jar snpEff.jar databases | tail -n +3 | cut -f 1,2 | awk '{ gsub(/_/, " ", $2); printf "%s\\t%s : %s\\n", $1, $2, $1 }' | sort -k 2 > snpeffect_genomedb.loc
+
+There are 2 datamanagers to download and install prebuilt SnpEff genome databases:
+
+* data_manager_snpeff_databases: generates a list of available SnpEff genome databases into the ``tool-data/snpeff_databases.loc`` file
+* data_manager_snpeff_download: downloads a SnpEff genome database selected from ``tool-data/snpeff_databases.loc`` and adds entries to ``snpeff_genomedb.loc``, ``snpeff_regulationdb.loc`` and ``snpeff_annotations.loc``
+
+SnpEff citation: |Cingolani2012program|_.
 
-There are 2 datamanagers to download and install prebuilt SnpEff Genome databases:
-  data_manager_snpeff_databases - generates a list of available SnpEff genome databases into the tool-data/snpeff_databases.loc 
-  data_manager_snpeff_download - downloads a SnpEff genome database selected from: tool-data/snpeff_databases.loc and adds entries to snpeff_genomedb.loc,snpeff_regulationdb.loc,snpeff_annotations.loc 
+.. |Cingolani2012program| replace:: Cingolani, P., Platts, A., Wang, L. L., Coon, M., Nguyen, T., Wang, L., Land, S. J., Lu, X., Ruden, D. M. (2012) A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of *Drosophila melanogaster* strain w1118; iso-2; iso-3. *Fly* 6(2):80-92
+.. _Cingolani2012program: https://www.landesbioscience.com/journals/fly/article/19695/
+
+SnpSift citation: |Cingolani2012using|_.
 
-SnpEff citation:
-"A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3.", Cingolani P, Platts A, Wang le L, Coon M, Nguyen T, Wang L, Land SJ, Lu X, Ruden DM. Fly (Austin). 2012 Apr-Jun;6(2):80-92. PMID: 22728672 [PubMed - in process]
+.. |Cingolani2012using| replace:: Cingolani, P., Patel, V. M., Coon, M., Nguyen, T., Land, S. J., Ruden, D. M., Lu, X. (2012) Using *Drosophila melanogaster* as a model for genotoxic chemical mutational studies with a new program, SnpSift. *Front. Genet.* 3:35
+.. _Cingolani2012using: http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00035/
 
-SnpSift citation:
-"Using Drosophila melanogaster as a model for genotoxic chemical mutational studies with a new program, SnpSift", Cingolani, P., et. al., Frontiers in Genetics, 3, 2012.
+Wrapper authors: Jim Johnson
+
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/repository_dependencies.xml	Thu Jan 22 08:28:37 2015 -0500
@@ -0,0 +1,4 @@
+<?xml version="1.0"?>
+<repositories description="This requires the SnpEff datatype definitions.">
+    <repository name="snpeff_datatypes" owner="iuc" changeset_revision="d78b2b2a3388" toolshed="http://toolshed.g2.bx.psu.edu" />
+</repositories>
--- a/snpEff.xml	Wed Dec 11 08:53:32 2013 -0500
+++ b/snpEff.xml	Thu Jan 22 08:28:37 2015 -0500
@@ -1,13 +1,14 @@
-<tool id="snpEff" name="SnpEff" version="3.4">
+<tool id="snpEff" name="SnpEff" version="@WRAPPER_VERSION@.0">
     <description>Variant effect and annotation</description>
     <expand macro="requirements" />
     <macros>
         <import>snpEff_macros.xml</import>
     </macros>
     <command>
+<![CDATA[
         java -Xmx6G -jar \$SNPEFF_JAR_PATH/snpEff.jar eff 
         -c \$SNPEFF_JAR_PATH/snpEff.config 
-        -i $inputFormat -o $outputFormat -upDownStreamLen $udLength 
+        -i $inputFormat -o ${outputConditional.outputFormat} -upDownStreamLen $udLength
         #if $spliceSiteSize and $spliceSiteSize.__str__ != '':
           -spliceSiteSize $spliceSiteSize
         #end if
@@ -34,7 +35,7 @@
         #if $statsFile:
           -stats $statsFile 
         #end if
-        #if $offset.__str__ != '':
+        #if $offset.__str__ != 'default':
           ${offset} 
         #end if
         #if $chr.__str__.strip() != '':
@@ -66,7 +67,19 @@
           -download
           $snpDb.genome_version
         #end if
-        $input > $snpeff_output 
+        $input > $snpeff_output ;
+        #if $statsFile:
+            #import os
+            #set $genes_file = str($statsFile) + '.genes.txt'
+            #set $genes_file_name = os.path.split($genes_file)[-1]
+            mkdir $statsFile.files_path;
+            mv $genes_file #echo os.path.join($statsFile.files_path, $genes_file_name)#;
+        #end if
+        #if $outputConditional.outputFormat == 'gatk' and $outputConditional.gatk_v1
+          ## Replace real SnpEff version with 2.0.5 to prevent this GATK 1.x error: "The version of SnpEff used to generate the SnpEff input file (x.x) is not currently supported by the GATK. Supported versions are: [2.0.5]"
+          sed -i 's/^\#\#SnpEffVersion="\(\S*\s\)/\#\#SnpEffVersion="2.0.5 - real is \1/' $snpeff_output
+        #end if
+]]>
     </command>
     <inputs>
         <param format="vcf,tabular,pileup,bed" name="input" type="data" label="Sequence changes (SNPs, MNPs, InDels)"/>
@@ -78,12 +91,22 @@
             <option value="bed">BED (Deprecated)</option>
         </param>
 
-        <param name="outputFormat" type="select" label="Output format">
-            <option value="vcf" selected="true">VCF (only if input is VCF)</option>
-            <option value="txt">Tabular</option>
-            <option value="bed">BED</option>
-            <option value="bedAnn">BED Annotations</option>
-        </param>
+        <conditional name="outputConditional">
+            <param name="outputFormat" type="select" label="Output format">
+                <option value="vcf" selected="true">VCF (only if input is VCF)</option>
+                <option value="gatk">GATK-compatible VCF (only if input is VCF)</option>
+                <option value="txt">Tabular</option>
+                <option value="bed">BED</option>
+                <option value="bedAnn">BED annotations</option>
+            </param>
+            <when value="vcf" />
+            <when value="gatk">
+                <param name="gatk_v1" type="boolean" checked="true" label="Compatible with GATK 1.x" />
+            </when>
+            <when value="txt" />
+            <when value="bed" />
+            <when value="bedAnn" />
+        </conditional>
 
         <conditional name="snpDb">
             <param name="genomeSrc" type="select" label="Genome source">
@@ -94,35 +117,41 @@
             <when value="cached">
                 <param name="genomeVersion" type="select" label="Genome">
                     <!--GENOME    DESCRIPTION-->
-                    <options from_data_table="snpeff_genomedb">
-                           <filter type="unique_value" column="0" />
+                    <options from_data_table="snpeffv_genomedb">
+                           <filter type="static_value" name="snpeff_version" value="@SNPEFF_VERSION@" column="1"/>
+                           <filter type="unique_value" column="2" />
                     </options>
                 </param>
-                <param name="extra_annotations" type="select" display="checkboxes" multiple="true" label="Additional Annotations">
+                <param name="extra_annotations" type="select" display="checkboxes" multiple="true" label="Additional annotations">
                        <help>These are available for only a few genomes</help>
-                       <options from_data_table="snpeff_annotations">
-                           <filter type="param_value" ref="genomeVersion" key="genome" column="0" />
-                           <filter type="unique_value" column="1" />
+                       <options from_data_table="snpeffv_annotations">
+                           <filter type="param_value" ref="genomeVersion" key="genome" column="2" />
+                           <filter type="unique_value" column="3" />
                        </options>
                 </param>
-                <param name="regulation" type="select" display="checkboxes" multiple="true" label="Non-coding and regulatory Annotation">
+                <param name="regulation" type="select" display="checkboxes" multiple="true" label="Non-coding and regulatory annotation">
                        <help>These are available for only a few genomes</help>
-                       <options from_data_table="snpeff_regulationdb">
-                           <filter type="param_value" ref="genomeVersion" key="genome" column="0" />
-                           <filter type="unique_value" column="1" />
+                       <options from_data_table="snpeffv_regulationdb">
+                           <filter type="param_value" ref="genomeVersion" key="genome" column="2" />
+                           <filter type="unique_value" column="3" />
                        </options>
                 </param>
             </when>
             <when value="history">
-                <param format="snpeffdb" name="snpeff_db" type="data" label="SnpEff Genome Version Data"/>
+                <param format="snpeffdb" name="snpeff_db" type="data" label="@SNPEFF_VERSION@ Genome Data">
+                    <options options_filter_attribute="metadata.snpeff_version" >
+                        <filter type="add_value" value="@SNPEFF_VERSION@" />
+                    </options>
+                    <validator type="expression" message="This version of SnpEff will only work with @SNPEFF_VERSION@ Genome databases.">value is not None and value.metadata.snpeff_version == "@SNPEFF_VERSION@"</validator>
+                </param>
                 <!-- From metadata -->
-                <param name="extra_annotations" type="select" display="checkboxes" multiple="true" label="Additional Annotations">
+                <param name="extra_annotations" type="select" display="checkboxes" multiple="true" label="Additional annotations">
                     <help>These are available for only a few genomes</help>
                     <options>
                         <filter type="data_meta" ref="snpeff_db" key="annotation" />
                     </options>
                 </param>
-                <param name="regulation" type="select" display="checkboxes" multiple="true" label="Non-coding and regulatory Annotation">
+                <param name="regulation" type="select" display="checkboxes" multiple="true" label="Non-coding and regulatory annotation">
                     <help>These are available for only a few genomes</help>
                     <options>
                         <filter type="data_meta" ref="snpeff_db" key="regulation" />
@@ -130,7 +159,10 @@
                 </param>
             </when>
             <when value="named">
-                <param name="genome_version" type="text" value="GRCh37.68" label="Snpff Version Name"/>
+                <param name="genome_version" type="text" size="40" value="" label="Snpff Genome Version Name (e.g. GRCh38.76)">
+                    <help>@SNPEFF_DATABASE_URL@</help>
+                    <validator type="regex" message="A genome version name is required">\S+</validator>
+                </param>
             </when>
         </conditional>
 
@@ -147,7 +179,7 @@
 
         <param name="spliceSiteSize" type="select" optional="true" label="Set size for splice sites (donor and acceptor) in bases" help="Default: 2">
             <option value="1">1 base</option>
-            <option value="2">2 bases</option>
+            <option value="2" selected="true">2 bases</option>
             <option value="3">3 bases</option>
             <option value="4">4 bases</option>
             <option value="5">5 bases</option>
@@ -159,28 +191,29 @@
 
         <param name="filterHomHet" type="select" display="radio" label="Filter homozygous / heterozygous changes">
             <option value="no_filter" selected="true">No filter (analyze everything)</option>
-            <option value="-hom">Analyze homozygous sequence changes only </option>
-            <option value="-het">Analyze heterozygous sequence changes only </option>
+            <option value="-hom">Analyze homozygous sequence changes only</option>
+            <option value="-het">Analyze heterozygous sequence changes only</option>
         </param>
 
         <!-- The tool testing code can not handle select,radio,check boxes values that start with '-', so the '-' is added in the command generation -->
         <param name="filterIn" type="select" display="radio" label="Filter sequence changes">
             <option value="no_filter" selected="true">No filter (analyze everything)</option>
-            <option value="-del">Analyze deletions only </option>
-            <option value="-ins">Analyze insertions only </option>
-            <option value="-mnp">Only MNPs (multiple nucleotide polymorphisms) </option>
-            <option value="-snp">Only SNPs (single nucleotide polymorphisms) </option>
+            <option value="-del">Analyze deletions only</option>
+            <option value="-ins">Analyze insertions only</option>
+            <option value="-mnp">Only MNPs (multiple nucleotide polymorphisms)</option>
+            <option value="-snp">Only SNPs (single nucleotide polymorphisms)</option>
         </param>
 
         <param name="annotations" type="select" display="checkboxes" multiple="true" label="Annotation options">
-            <option value="-cancer">Perform 'cancer' comparissons (Somatic vs Germline)</option>
+            <option value="-cancer">Perform 'cancer' comparisons (somatic vs. germline)</option>
             <option value="-canon">Only use canonical transcripts</option>
             <option value="-geneId">Use gene ID instead of gene name (VCF output)</option>
-            <option value="-hgvs">Use HGVS annotations for amino acid sub-field</option>
-            <option value="-lof">Add loss of function (LOF) and Nonsense mediated decay (NMD) tags</option>
+            <option value="-lof">Add loss of function (LOF) and nonsense mediated decay (NMD) tags</option>
             <option value="-oicr">Add OICR tag in VCF file</option>
             <option value="-onlyReg">Only use regulation tracks</option>
-            <option value="-sequenceOntolgy">Use Sequence Ontolgy terms.</option>
+            <option value="-classic">Use Classic Effect names and amino acid variant annotations (NON_SYNONYMOUS_CODING vs missense_variant and G180R vs p.Gly180Arg/c.538G>C)</option>
+            <option value="-hgvs">Override classic and use HGVS annotations for amino acid annotations (p.Gly180Arg/c.538G>C vs G180R)</option>
+            <option value="-sequenceOntology">Override classic and use Sequence Ontolgy terms for effects (missense_variant vs NON_SYNONYMOUS_CODING)</option>
         </param>
         <param name="intervals" format="bed" type="data" optional="true" label="Use custom interval file for annotation"/>
         <param name="transcripts" format="tabular" type="data" optional="true" label="Only use the transcripts in this file." help="Format is one transcript ID per line."/>
@@ -193,7 +226,7 @@
         </param>
 
         <param name="offset" type="select" display="radio" optional="true" label="Chromosomal position">
-            <option value="" selected="true">Use default (based on input type)</option>
+            <option value="default" selected="true">Use default (based on input type)</option>
             <option value="-0">Force zero-based positions (both input and output)</option>
             <option value="-1">Force one-based positions (both input and output)</option>
         </param>
@@ -210,13 +243,12 @@
     <outputs>
         <data format="vcf" name="snpeff_output" >
             <change_format>
-                <when input="outputFormat" value="vcf" format="vcf" />
-                <when input="outputFormat" value="txt" format="tabular" />
-                <when input="outputFormat" value="bed" format="bed" />
-                <when input="outputFormat" value="bedAnn" format="bed" />
+                <when input="outputConditional.outputFormat" value="txt" format="tabular" />
+                <when input="outputConditional.outputFormat" value="bed" format="bed" />
+                <when input="outputConditional.outputFormat" value="bedAnn" format="bed" />
             </change_format>
         </data>
-        <data format="html" name="statsFile">
+        <data format="html" name="statsFile" label="${tool.name} on ${on_string} - stats">
             <filter>generate_stats == True</filter>
         </data>
     </outputs>
@@ -280,7 +312,7 @@
         <param name="genome_version" value="testCase"/>
         <param name="udLength" value="0"/>
         <param name="filterHomHet" value="no_filter"/>
-        <param name="filterIn" value="del"/>
+        <param name="filterIn" value="+-del"/>
         <!--
         <param name="filterOut" value=""/>
         -->
@@ -326,5 +358,6 @@
 @CITATION_SECTION@
 
     </help>
+    <expand macro="citations" />
 </tool>
 
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/snpEff_databases.xml	Thu Jan 22 08:28:37 2015 -0500
@@ -0,0 +1,26 @@
+<tool id="snpEff_databases" name="SnpEff Available Databases" version="@WRAPPER_VERSION@.0">
+    <description></description>
+    <expand macro="requirements" />
+    <macros>
+        <import>snpEff_macros.xml</import>
+    </macros>
+    <command>
+<![CDATA[
+    java -jar \$SNPEFF_JAR_PATH/snpEff.jar databases |  grep -v '^---' | sed 's/^Genome/#Genome/' | sed  's/  *//g' > $snpeff_dbs 
+]]>
+    </command>
+    <inputs>
+    </inputs>
+    <outputs>
+        <data format="tabular" name="snpeff_dbs" label="${tool.name} @SNPEFF_VERSION@ available databases" />
+    </outputs>
+    <expand macro="stdio" />
+    <help>
+
+@EXTERNAL_DOCUMENTATION@
+
+@CITATION_SECTION@
+
+    </help>
+</tool>
+
--- a/snpEff_download.xml	Wed Dec 11 08:53:32 2013 -0500
+++ b/snpEff_download.xml	Thu Jan 22 08:28:37 2015 -0500
@@ -1,23 +1,22 @@
-<tool id="snpEff_download" name="SnpEff Download" version="3.4">
+<tool id="snpEff_download" name="SnpEff Download" version="@WRAPPER_VERSION@.0">
     <description>Download a new database</description>
     <expand macro="requirements" />
     <macros>
         <import>snpEff_macros.xml</import>
     </macros>
     <command>
-    echo $genomeVersion > $snpeff_db; 
-    java -jar \$SNPEFF_JAR_PATH/snpEff.jar download -c \$SNPEFF_JAR_PATH/snpEff.config -dataDir $snpeff_db.extra_files_path -v $genomeVersion > $logfile 
+<![CDATA[
+    java -jar \$SNPEFF_JAR_PATH/snpEff.jar download -c \$SNPEFF_JAR_PATH/snpEff.config -dataDir $snpeff_db.files_path -v $genome_version 
+]]>
     </command>
     <inputs>
-        <param name="genomeVersion" type="select" label="Select the genome version you want to download">
-            <options from_data_table="snpeff_databases">
-                <filter type="sort_by" column="0" />
-            </options>
+        <param name="genome_version" type="text" size="40" value="" label="Select the genome version you want to download (e.g. GRCh37.74)">
+            <help>@SNPEFF_DATABASE_URL@</help>
+            <validator type="regex" message="A genome version name is required">\S+</validator>
         </param>
     </inputs>
     <outputs>
-        <data format="txt" name="logfile" />
-        <data format="snpeffdb" name="snpeff_db" label="${genomeVersion}" />
+        <data format="snpeffdb" name="snpeff_db" label="${tool.name} @SNPEFF_VERSION@ ${genome_version}" />
     </outputs>
     <expand macro="stdio" />
     <help>
@@ -27,5 +26,6 @@
 @CITATION_SECTION@
 
     </help>
+    <expand macro="citations" />
 </tool>
 
--- a/snpEff_macros.xml	Wed Dec 11 08:53:32 2013 -0500
+++ b/snpEff_macros.xml	Thu Jan 22 08:28:37 2015 -0500
@@ -1,7 +1,7 @@
 <macros>
     <xml name="requirements">
         <requirements>
-            <requirement type="package" version="3.4">snpEff</requirement>
+            <requirement type="package" version="4.0">snpEff</requirement>
         </requirements>
     </xml>
   <xml name="stdio">
@@ -10,9 +10,13 @@
         <exit_code range="1:"  level="fatal" description="Error" />
     </stdio>
   </xml>
+  <token name="@WRAPPER_VERSION@">4.0</token>
+  <token name="@SNPEFF_VERSION@">SnpEff4.0</token>
+  <token name="@SNPEFF_DATABASE_URL@">https://snpeff-data.galaxyproject.org/databases/v4_0/</token>
   <token name="@EXTERNAL_DOCUMENTATION@">
 
-For details about this tool, please go to http://snpeff.sourceforge.net/SnpSift.html#intervals
+For details about this tool, please go to:
+	http://snpeff.sourceforge.net/SnpEff_manual.html
 
   </token>
   <token name="@CITATION_SECTION@">------
@@ -22,10 +26,13 @@
 For the underlying tool, please cite the following two publications:
 
 SnpEff citation:
-"A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3.", Cingolani P, Platts A, Wang le L, Coon M, Nguyen T, Wang L, Land SJ, Lu X, Ruden DM. Fly (Austin). 2012 Apr-Jun;6(2):80-92. PMID: 22728672 [PubMed - in process]
-
-SnpSift citation:
-"Using Drosophila melanogaster as a model for genotoxic chemical mutational studies with a new program, SnpSift", Cingolani, P., et. al., Frontiers in Genetics, 3, 2012.
+"A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3.", Cingolani P, Platts A, Wang le L, Coon M, Nguyen T, Wang L, Land SJ, Lu X, Ruden DM. Fly 6(2):80-92, 2012
 
   </token>
+  <xml name="citations">
+      <citations>
+        <citation type="doi">10.4161/fly.19695</citation>
+        <yield />
+      </citations>
+  </xml>
 </macros>
--- a/snpSift_annotate.xml	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,99 +0,0 @@
-<tool id="snpSift_annotate" name="SnpSift Annotate" version="3.4">
-    <description>SNPs from dbSnp</description>
-    <!-- 
-        You can change the amount of memory used, just change the -Xmx parameter (e.g. use -Xmx2G for 2Gb of memory)
-    -->
-    <expand macro="requirements" />
-    <macros>
-        <import>snpEff_macros.xml</import>
-    </macros>
-    <command>
-        java -Xmx6G -jar \$SNPEFF_JAR_PATH/SnpSift.jar $annotate_cmd 
-        #if $annotate.id :
-          -id
-        #elif $annotate.info_ids.__str__.strip() != '' :
-          -info "$annotate.info_ids"
-        #end if          
-        -q $dbSnp $input > $output 
-    </command>
-    <inputs>
-        <param format="vcf" name="input" type="data" label="Variant input file in VCF format"/>
-        <param format="vcf" name="dbSnp" type="data" label="VCF File with ID field annotated (e.g. dnSNP.vcf)" 
-            help="The ID field for a variant in input will be assigned from a matching variant in this file."/>
-        <conditional name="annotate">
-            <param name="id" type="boolean" truevalue="id" falsevalue="info" checked="True" label="Only annotate ID field (do not add INFO field)" help=""/>
-            <when value="id"/>
-            <when value="info">
-                <param name="info_ids" type="text" value="" size="60" optional="true" label="Limit INFO annotation to these INFO IDs"
-                    help="list is a comma separated list of fields. When blank, all INFO fields are included">    
-                    <validator type="regex" message="IDs separted by commas">^(([a-zA-Z][a-zA-Z0-9_-]*)(,[a-zA-Z][a-zA-Z0-9_-]*)*)?$</validator>
-                </param>
-            </when>
-        </conditional>
-        <param name="annotate_cmd" type="boolean" truevalue="annMem" falsevalue="annotate" checked="false" label="Allow unsorted VCF files"> 
-            <help>
-                This option will load the entire 'database' VCF file into memory (which may not be practical for large 'database' VCF files).
-                Otherwise, both the database and the input VCF files should be sorted by position (Chromosome sort order can differ between files). 
-            </help>
-            </param>
-    </inputs>
-    <expand macro="stdio" />
-    <outputs>
-        <data format="vcf" name="output" />
-    </outputs>
-    <tests>
-        <test>
-            <param name="input" ftype="vcf" value="annotate_1.vcf"/>
-            <param name="dbSnp" ftype="vcf" value="db_test_1.vcf"/>
-            <param name="annotate_cmd" value="False"/>
-            <param name="id" value="True"/>
-            <output name="output">
-                <assert_contents>
-                    <has_text text="rs76166080" />
-                </assert_contents>
-            </output>
-        </test>
-    </tests>
-    <help>
-
-This is typically used to annotate IDs from dbSnp.
-
-Annotatating only the ID field from dbSnp137.vcf ::
-
-    Input VCF:
-    CHROM  POS         ID           REF  ALT  QUAL   FILTER  INFO
-    22      16157571    .            T    G    0.0    FAIL    NS=53
-    22      16346045    .            T    C    0.0    FAIL    NS=244
-    22      16350245    .            C    A    0.0    FAIL    NS=192
-
-    Annotated Output VCF:
-    #CHROM  POS         ID           REF  ALT  QUAL   FILTER  INFO
-    22      16157571    .            T    G    0.0    FAIL    NS=53
-    22      16346045    rs56234788   T    C    0.0    FAIL    NS=244
-    22      16350245    rs2905295    C    A    0.0    FAIL    NS=192
-
-
-
-Annotatating both the ID and INFO fields from dbSnp137.vcf ::
-
-    Input VCF:
-    #CHROM  POS         ID           REF  ALT  QUAL   FILTER  INFO
-    22      16157571    .            T    G    0.0    FAIL    NS=53
-    22      16346045    .            T    C    0.0    FAIL    NS=244
-    22      16350245    .            C    A    0.0    FAIL    NS=192
-
-    Annotated Output VCF:
-    #CHROM  POS         ID           REF  ALT  QUAL   FILTER  INFO
-    22      16157571    .            T    G    0.0    FAIL    NS=53
-    22      16346045    rs56234788   T    C    0.0    FAIL    NS=244;RSPOS=16346045;GMAF=0.162248628884826;dbSNPBuildID=129;SSR=0;SAO=0;VP=050100000000000100000100;WGT=0;VC=SNV;SLO;GNO
-    22      16350245    rs2905295    C    A    0.0    FAIL    NS=192;RSPOS=16350245;GMAF=0.230804387568556;dbSNPBuildID=101;SSR=1;SAO=0;VP=050000000000000100000140;WGT=0;VC=SNV;GNO
-
-
-@EXTERNAL_DOCUMENTATION@
-
-@CITATION_SECTION@
-
-
-    </help>
-</tool>
-
--- a/snpSift_caseControl.xml	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,121 +0,0 @@
-<tool id="snpSift_caseControl" name="SnpSift CaseControl" version="3.4">
-    <description>Count samples are in 'case' and 'control' groups.</description>
-    <!-- 
-        You can change the amount of memory used, just change the -Xmx parameter (e.g. use -Xmx2G for 2Gb of memory)
-    -->
-    <expand macro="requirements" />
-    <macros>
-        <import>snpEff_macros.xml</import>
-    </macros>
-    <command>
-    java -Xmx1G -jar \$SNPEFF_JAR_PATH/SnpSift.jar caseControl -q 
-    #if $name.__str__.strip() != '':
-      -name $name
-    #end if
-    #if $ctrl.ctrl_src == 'caseString':
-      '$ctrl.caseControlStr' 
-    #else
-      -tfam "$ctrl.tfam"
-    #end if
-    $input > $output
-    </command>
-    <inputs>
-        <param format="vcf" name="input" type="data" label="Variant input file in VCF format"/>
-        <conditional name="ctrl">
-            <param name="ctrl_src" type="select" label="Case Control defined in">
-            <option value="caseString">Case Control String</option>
-            <option value="tfam">TFAM file</option>
-        </param>
-        <when value="caseString">
-            <param name="caseControlStr" type="text" label="Case / Control column designation" size="50">
-            <help>
-                Case and control are defined by a string containing plus and minus symbols {'+', '-', '0'} where '+' is case, '-' is control and '0' is neutral
-            </help>
-            <validator type="regex" message="must be  only plus(+), minus(-), or zero(0) characters">[+-0]+</validator>
-            </param>
-        </when>
-        <when value="tfam">
-            <param format="tabular" name="tfam" type="data" label="PLINK TFAM file" help="Read more about TFAM at http://pngu.mgh.harvard.edu/~purcell/plink/data.shtml#tr"/>
-        </when>
-        </conditional>
-        <param name="name" type="text" optional="true" label="name" help="name to append to the 'Cases' or 'Controls' tags">
-            <validator type="regex" message="Use only valid ID characters">[_a-zA-Z0-9]+</validator>
-        </param>
-    </inputs>
-    <outputs>
-        <data format="vcf" name="output" />
-    </outputs>
-    <expand macro="stdio" />
-    <tests>
-        <test>
-            <param name="input" ftype="vcf" value="test.private.01.vcf"/>
-            <param name="ctrl_src" value="caseString"/>
-            <param name="caseControlStr" value="--"/>
-            <output name="output">
-                <assert_contents>
-                    <has_text text="Cases=0,0,0;" />
-                    <has_text text="Controls=0,0,0;" />
-                </assert_contents>
-            </output>
-        </test>
-
-        <test>
-            <param name="input" ftype="vcf" value="test.private.02.vcf"/>
-            <param name="ctrl_src" value="caseString"/>
-            <param name="caseControlStr" value="--"/>
-            <output name="output">
-                <assert_contents>
-                    <has_text text="Cases=0,0,0;" />
-                    <has_text text="Controls=2,0,4;" />
-                </assert_contents>
-            </output>
-        </test>
-
-        <test>
-            <param name="input" ftype="vcf" value="test.private.02.vcf"/>
-            <param name="name" value=""/>
-            <param name="ctrl_src" value="caseString"/>
-            <param name="caseControlStr" value="-+"/>
-            <output name="output">
-                <assert_contents>
-                    <has_text text="Cases=1,0,2;" />
-                    <has_text text="Controls=1,0,2;" />
-                </assert_contents>
-            </output>
-        </test>
-    </tests>
-    <help>
-
-**SnpSift CaseControl**
-
-Allows you to count how many samples are in 'case' group and a 'control' group. You can count 'homozygous', 'heterozygous' or 'any' variants. 
-
-Case and control are defined by a string containing plus and minus symbols {'+', '-', '0'} where '+' is case, '-' is control and '0' is neutral. 
-
-This command adds two annotations to the VCF file:
-
- - **CaseControl**: Two comma separated numbers numbers representing the number of samples that have the variant in the case and the control group. Example: 
-
-  "CaseControl=3,4" *the variant is present in 3 cases and 4 controls.*
-
-
- - **CaseControlP**: A p-value (Fisher exact test) that the number of cases is N or more. Example:
-
-  "CaseControl=4,0;CaseControlP=3.030303e-02" *in this case the pValue of having 4 or more cases and zero controls is 0.03*
-
-
-For example, if we have ten samples (which means ten genotype columns in the VCF file), the first four are 'case' and the last six are 'control', so the description string would be "++++------".  Let's say we want to distinguish genotypes that are homozygous in 'case' and either homozygous or heterozygous in 'control'.  We would set:
-
-  - Hom/Het case = "hom"
-
-  - Hom/Het control = "any"  
-
-  - Case / Control column designation = ""++++------"
-
-
-@EXTERNAL_DOCUMENTATION@
-
-@CITATION_SECTION@
-
-  </help>
-</tool>
--- a/snpSift_filter.xml	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,148 +0,0 @@
-<tool id="snpSift_filter" name="SnpSift Filter" version="3.4">
-    <options sanitize="False" />
-    <description>Filter variants using arbitrary expressions</description>
-    <expand macro="requirements" />
-    <macros>
-        <import>snpEff_macros.xml</import>
-    </macros>
-    <command>
-        java -Xmx6G -jar \$SNPEFF_JAR_PATH/SnpSift.jar filter -f $input -e $exprFile $inverse 
-        #if $filtering.mode == 'field':
-            #if $filtering.replace.pass:
-                --pass
-                #if $filtering.replace.filterId and len($filtering.replace.filterId.__str__.strip()) > 0:
-                    --filterId "$filtering.replace.filterId"
-                #end if
-            #end if
-            #if $filtering.addFilter and len($filtering.addFilter.__str__.strip()) > 0:
-                --addFilter "$filtering.addFilter"
-            #end if
-            #if $filtering.rmFilter and len($filtering.rmFilter.__str__.strip()) > 0:
-                --rmFilter "$filtering.rmFilter"
-            #end if
-        #end if
-         > $output
-    </command>
-    <inputs>
-        <param format="vcf" name="input" type="data" label="Variant input file in VCF format"/>
-        <param name="expr" type="text" label="Filter criteria" size="160" help="Need help? See below a few examples." />
-        <param name="inverse" type="boolean" truevalue="--inverse" falsevalue="" checked="false" label="Inverse filter" help="Show lines that do not match filter expression" />
-        <conditional name="filtering">
-            <param name="mode" type="select" label="Filter mode">
-                <option value="entries" selected="true">Retain entries that pass filter, remove other entries</option>
-                <option value="field">Change the FILTER field, but retain all entries</option>
-            </param> 
-            <when value="entries"/>
-            <when value="field">
-                <conditional name="replace">
-                    <param name="pass" type="boolean" truevalue="yes" falsevalue="no" checked="false" label="Set matching entry FILTER to 'PASS'" 
-                           help="appends an ID tag to non-matching entry FILTER "/>
-                    <when value="no"/>
-                    <when value="yes">
-                        <param name="filterId" type="text" value="" optional="true" label="ID appended to non-matching (##FILTER tag in header and FILTER VCF field)." size="10"
-                               help="Default ID is 'SnpSift'"/>
-                    </when>
-                </conditional>
-                <param name="addFilter" type="text" value="" optional="true" label="Add a string to FILTER VCF field if 'expression' is true." size="10"/>
-                <param name="rmFilter" type="text" value="" optional="true" label="Remove a string from FILTER VCF field if 'expression' is true (and 'str' is in the field)." size="10"/>
-            </when>
-        </conditional>
-    </inputs>
-    <configfiles>
-        <configfile name="exprFile">
-        $expr
-        </configfile> 
-    </configfiles>
-
-    <outputs>
-        <data format="vcf" name="output" />
-    </outputs>
-    <expand macro="stdio" />
-    <tests>
-        <test>
-        <param name="input" ftype="vcf" value="test01.vcf"/>
-        <param name="expr" value="QUAL >= 50"/>
-        <param name="mode" value="entries"/>
-        <output name="output">
-            <assert_contents>
-            <has_text text="28837706" />
-            <not_has_text text="NT_166464" />
-            </assert_contents>
-        </output>
-        </test>
-
-        <test>
-        <param name="input" ftype="vcf" value="test01.vcf"/>
-        <param name="expr" value="(CHROM = '19')"/>
-        <param name="mode" value="entries"/>
-        <output name="output">
-            <assert_contents>
-            <has_text text="3205820" />
-            <not_has_text text="NT_16" />
-            </assert_contents>
-        </output>
-        </test>
-
-        <test>
-        <param name="input" ftype="vcf" value="test01.vcf"/>
-        <param name="expr" value="(POS >= 20175) &amp; (POS &lt;= 35549)"/>
-        <param name="mode" value="entries"/>
-        <output name="output">
-            <assert_contents>
-            <has_text text="20175" />
-            <has_text text="35549" />
-            <has_text text="22256" />
-            <not_has_text text="18933" />
-            <not_has_text text="37567" />
-            </assert_contents>
-        </output>
-        </test>
-
-        <test>
-        <param name="input" ftype="vcf" value="test01.vcf"/>
-        <param name="expr" value="( DP >= 5 )"/>
-        <param name="mode" value="entries"/>
-        <output name="output">
-            <assert_contents>
-            <has_text text="DP=5;" />
-            <has_text text="DP=6;" />
-            <not_has_text text="DP=1;" />
-            </assert_contents>
-        </output>
-        </test>
-    </tests>
-    <help>
-
-**SnpSift filter**
-
-You can filter ia vcf file using arbitrary expressions, for instance "(QUAL > 30) | (exists INDEL) | ( countHet() > 2 )". The actual expressions can be quite complex, so it allows for a lot of flexibility.
-
-Some examples:
-
-  - *I want to filter out samples with quality less than 30*:
-
-    * **( QUAL &gt; 30 )**
-
-  - *...but we also want InDels that have quality 20 or more*:
-
-    * **(( exists INDEL ) &amp; (QUAL >= 20)) | (QUAL >= 30 )**
-
-  - *...or any homozygous variant present in more than 3 samples*:
-
-    * **(countHom() > 3) | (( exists INDEL ) &amp; (QUAL >= 20)) | (QUAL >= 30 )**
-
-  - *...or any heterozygous sample with coverage 25 or more*:
-
-    * **((countHet() > 0) &amp; (DP >= 25)) | (countHom() > 3) | (( exists INDEL ) &amp; (QUAL >= 20)) | (QUAL >= 30 )**
-
-  - *I want to keep samples where the genotype for the first sample is homozygous variant and the genotype for the second sample is reference*:
-
-    * **isHom( GEN[0] ) &amp; isVariant( GEN[0] ) &amp; isRef( GEN[1] )**
-
-
-@EXTERNAL_DOCUMENTATION@
-
-@CITATION_SECTION@
-
-    </help>
-</tool>
--- a/snpSift_int.xml	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,56 +0,0 @@
-<tool id="snpSift_int" name="SnpSift Intervals" version="3.4">
-    <description>Filter variants using intervals</description>
-    <!-- 
-        You can change the amount of memory used, just change the -Xmx parameter (e.g. use -Xmx2G for 2Gb of memory)
-    -->
-    <expand macro="requirements" />
-    <macros>
-        <import>snpEff_macros.xml</import>
-    </macros>
-    <command>
-        java -Xmx2G -jar \$SNPEFF_JAR_PATH/SnpSift.jar intervals -i $input $exclude $bedFile > $output
-    </command>
-    <inputs>
-        <param format="vcf" name="input" type="data" label="Variant input file in VCF format"/>
-        <param format="bed" name="bedFile" type="data" label="Intervals (BED file)"/>
-        <param name="exclude" type="boolean" truevalue="-x" falsevalue="" checked="false" label="Exclude Intervals" 
-            help="Filter out (exclude) VCF entries that match any interval in the BED files"/>
-    </inputs>
-    <outputs>
-        <data format="vcf" name="output" />
-    </outputs>
-    <expand macro="stdio" />
-    <tests>
-        <test>
-            <param name="input" ftype="vcf" value="annotate_5.vcf"/>
-            <param name="bedFile" ftype="bed" value="interval.bed"/>
-            <param name="exclude" value="False"/>
-            <output name="output">
-                <assert_contents>
-                    <has_text text="872687" />
-                    <not_has_text text="1195966" />
-                </assert_contents>
-            </output>
-        </test>
-        <test>
-            <param name="input" ftype="vcf" value="annotate_5.vcf"/>
-            <param name="bedFile" ftype="bed" value="interval.bed"/>
-            <param name="exclude" value="True"/>
-            <output name="output">
-                <assert_contents>
-                    <has_text text="1195966" />
-                    <not_has_text text="872687" />
-                </assert_contents>
-            </output>
-        </test>
-    </tests>
-    <help>
-
-You can filter using intervals (BED file).
-
-@EXTERNAL_DOCUMENTATION@
-
-@CITATION_SECTION@
-
-    </help>
-</tool>
--- a/test-data/annotate_1.vcf	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,1 +0,0 @@
-1	872687	.	C	G	.	.	.
--- a/test-data/annotate_5.vcf	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,5 +0,0 @@
-1	872687	rs76166080	C	G	.	.	.
-1	970878	.	C	T	.	.	.
-1	979690	rs115413462	G	A	.	.	.
-1	1160967	.	C	T	.	.	.
-1	1195966	rs114569001	G	A	.	.	.
--- a/test-data/db_test_1.vcf	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,1 +0,0 @@
-1	872687	rs76166080	C	G	0	.	.
--- a/test-data/interval.bed	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,10 +0,0 @@
-chr1	1	100000
-chr1	100000	200000
-chr1	200000	300000
-chr1	300000	400000
-chr1	400000	500000
-chr1	500000	600000
-chr1	600000	700000
-chr1	700000	800000
-chr1	800000	900000
-chr1	900000	1000000
--- a/test-data/test.private.01.vcf	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,3 +0,0 @@
-##fileformat=VCFv4.0
-#CHROM	POS	ID	REF	ALT	QUAL	FILTER	INFO	FORMAT	id1	id2
-1	123456	.	A	G	.	.	AF=0	GT	0/0	0/0	
--- a/test-data/test.private.02.vcf	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,3 +0,0 @@
-##fileformat=VCFv4.0
-#CHROM	POS	ID	REF	ALT	QUAL	FILTER	INFO	FORMAT	id1	id2
-1	123456	.	A	G	.	.	AF=0	GT	1/1	1/1	
--- a/test-data/test01.vcf	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,1000 +0,0 @@
-##fileformat=VCFv4.1
-##samtoolsVersion=0.1.16 (r963:234)
-##INFO=<ID=DP,Number=1,Type=Integer,Description="Raw read depth">
-##INFO=<ID=DP4,Number=4,Type=Integer,Description="# high-quality ref-forward bases, ref-reverse, alt-forward and alt-reverse bases">
-##INFO=<ID=MQ,Number=1,Type=Integer,Description="Root-mean-square mapping quality of covering reads">
-##INFO=<ID=FQ,Number=1,Type=Float,Description="Phred probability of all samples being the same">
-##INFO=<ID=AF1,Number=1,Type=Float,Description="Max-likelihood estimate of the site allele frequency of the first ALT allele">
-##INFO=<ID=G3,Number=3,Type=Float,Description="ML estimate of genotype frequencies">
-##INFO=<ID=HWE,Number=1,Type=Float,Description="Chi^2 based HWE test P-value based on G3">
-##INFO=<ID=CI95,Number=2,Type=Float,Description="Equal-tail Bayesian credible interval of the site allele frequency at the 95% level">
-##INFO=<ID=PV4,Number=4,Type=Float,Description="P-values for strand bias, baseQ bias, mapQ bias and tail distance bias">
-##INFO=<ID=INDEL,Number=0,Type=Flag,Description="Indicates that the variant is an INDEL.">
-##INFO=<ID=PC2,Number=2,Type=Integer,Description="Phred probability of the nonRef allele frequency in group1 samples being larger (,smaller) than in group2.">
-##INFO=<ID=PCHI2,Number=1,Type=Float,Description="Posterior weighted chi^2 P-value for testing the association between group1 and group2 samples.">
-##INFO=<ID=QCHI2,Number=1,Type=Integer,Description="Phred scaled PCHI2.">
-##INFO=<ID=PR,Number=1,Type=Integer,Description="# permutations yielding a smaller PCHI2.">
-##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype">
-##FORMAT=<ID=GQ,Number=1,Type=Integer,Description="Genotype Quality">
-##FORMAT=<ID=GL,Number=3,Type=Float,Description="Likelihoods for RR,RA,AA genotypes (R=ref,A=alt)">
-##FORMAT=<ID=DP,Number=1,Type=Integer,Description="# high-quality bases">
-##FORMAT=<ID=SP,Number=1,Type=Integer,Description="Phred-scaled strand bias P-value">
-##FORMAT=<ID=PL,Number=-1,Type=Integer,Description="List of Phred-scaled genotype likelihoods, number of values is (#ALT+1)*(#ALT+2)/2">
-#CHROM	POS	ID	REF	ALT	QUAL	FILTER	INFO	FORMAT	s_1_BcA2.sort.rmdup.Q20.noMh.bam
-NT_166464	696	.	G	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166464	745	.	G	C	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-NT_166464	7258	.	A	C	40	.	DP=4;AF1=0.5008;CI95=0.5,0.5;DP4=1,0,2,1;MQ=32;FQ=-4.12;PV4=1,0.28,0.21,0.17	GT:PL:GQ	0/1:70,0,25:28
-NT_166464	7268	.	A	G	8.65	.	DP=4;AF1=0.5004;CI95=0.5,0.5;DP4=1,0,1,1;MQ=30;FQ=3.32;PV4=1,0.017,0,1	GT:PL:GQ	0/1:38,0,28:32
-NT_166464	7283	.	T	C	11.3	.	DP=3;AF1=0.501;CI95=0.5,0.5;DP4=1,0,1,1;MQ=30;FQ=-4.81;PV4=1,1,0,1	GT:PL:GQ	0/1:41,0,24:28
-NT_166464	7335	.	G	A	18.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=25;FQ=-33	GT:PL:GQ	1/1:50,6,0:10
-NT_166464	8030	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166452	8268	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166452	16693	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166480	12474	.	G	A	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-NT_166480	12483	.	A	G	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-NT_166476	578	.	C	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166476	22223	.	A	C	3.01	.	DP=4;AF1=0.4998;CI95=0.5,0.5;DP4=0,2,2,0;MQ=32;FQ=4.63;PV4=0.33,0.26,0,0.42	GT:PL:GQ	0/1:30,0,43:28
-NT_166476	22256	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166476	23076	.	A	T	8.44	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=25;FQ=-33	GT:PL:GQ	1/1:39,6,0:8
-NT_166476	23487	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166454	64	.	T	A	8.64	.	DP=7;AF1=0.5;CI95=0.5,0.5;DP4=1,4,2,0;MQ=29;FQ=11.3;PV4=0.14,1,1,1	GT:PL:GQ	0/1:38,0,91:40
-NT_166454	95	.	T	A	9.52	.	DP=7;AF1=0.5;CI95=0.5,0.5;DP4=2,3,1,1;MQ=29;FQ=12.3;PV4=1,0.19,1,1	GT:PL:GQ	0/1:39,0,101:41
-NT_166454	1580	.	T	C	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-NT_166454	7132	.	A	G	42.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:74,6,0:10
-NT_166454	7142	.	T	C	42.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:74,6,0:10
-NT_166454	7181	.	C	A	11.1	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:42,6,0:9
-NT_166454	11670	.	C	T	4.61	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-33	GT:PL:GQ	1/1:34,6,0:5
-NT_166454	15049	.	A	T	13.9	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:45,6,0:10
-NT_166454	15052	.	TA	T	35.2	.	INDEL;DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:74,6,0:10
-NT_166454	15373	.	C	G	30.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-33	GT:PL:GQ	1/1:62,6,0:10
-NT_166454	15388	.	C	G	22.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-33	GT:PL:GQ	1/1:54,6,0:10
-NT_166454	15440	.	TA	T	28.2	.	INDEL;DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:67,6,0:10
-NT_166454	18840	.	C	T	6.79	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=25;FQ=-33	GT:PL:GQ	1/1:37,6,0:7
-NT_166454	18863	.	T	C	13.9	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=25;FQ=-33	GT:PL:GQ	1/1:45,6,0:10
-NT_166454	18933	.	C	T	4.77	.	DP=3;AF1=0.5003;CI95=0.5,0.5;DP4=1,0,2,0;MQ=30;FQ=-3.1;PV4=1,0.032,0,0.31	GT:PL:GQ	0/1:33,0,28:30
-NT_166454	21433	.	G	T	6.02	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:36,6,0:6
-NT_166454	21485	.	TAAAAA	TAAAA	17.5	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,1,2;MQ=37;FQ=-43.5	GT:PL:GQ	1/1:57,9,0:15
-NT_166481	473	.	A	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166481	476	.	A	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166481	558	.	G	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166481	9526	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166481	10879	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166481	17878	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166481	20402	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166481	20413	.	G	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166459	13329	.	T	G	20.1	.	DP=3;AF1=0.5013;CI95=0.5,0.5;DP4=1,0,1,1;MQ=37;FQ=-5.45;PV4=1,0.48,1,0.33	GT:PL:GQ	0/1:50,0,23:26
-NT_166459	21532	.	T	C	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-NT_166473	10619	.	T	A	4.13	.	DP=4;AF1=0.5003;CI95=0.5,0.5;DP4=1,0,0,3;MQ=28;FQ=-3.64;PV4=0.25,0.036,0,1	GT:PL:GQ	0/1:32,0,27:29
-NT_166473	10641	.	A	T	47.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,3;MQ=28;FQ=-39	GT:PL:GQ	1/1:80,12,0:21
-NT_166461	20175	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166462	4505	.	A	G	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-NT_166462	4585	.	C	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166462	25794	.	A	C	7.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166462	25801	.	T	G	22.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-33	GT:PL:GQ	1/1:54,6,0:10
-NT_166462	25952	.	T	C	32.1	.	DP=9;AF1=1;CI95=0.5,1;DP4=0,0,6,0;MQ=37;FQ=-45	GT:PL:GQ	1/1:65,18,0:33
-NT_166462	25967	.	T	C	135	.	DP=9;AF1=1;CI95=1,1;DP4=0,0,9,0;MQ=37;FQ=-54	GT:PL:GQ	1/1:168,27,0:51
-NT_166462	26035	.	T	C	82	.	DP=9;AF1=1;CI95=1,1;DP4=0,0,9,0;MQ=37;FQ=-54	GT:PL:GQ	1/1:115,27,0:51
-NT_166462	26537	.	C	G	83.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,3;MQ=37;FQ=-39	GT:PL:GQ	1/1:116,12,0:21
-NT_166462	26577	.	A	C	29.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,3;MQ=37;FQ=-39	GT:PL:GQ	1/1:62,12,0:21
-NT_166462	26682	.	A	G	222	.	DP=19;AF1=1;CI95=1,1;DP4=0,0,9,9;MQ=30;FQ=-81	GT:PL:GQ	1/1:255,54,0:99
-NT_166462	26690	.	A	G	184	.	DP=20;AF1=1;CI95=1,1;DP4=0,0,10,10;MQ=31;FQ=-87	GT:PL:GQ	1/1:217,60,0:99
-NT_166462	26717	.	A	G	207	.	DP=10;AF1=1;CI95=1,1;DP4=0,0,6,4;MQ=36;FQ=-57	GT:PL:GQ	1/1:240,30,0:57
-NT_166462	26722	.	T	C	98	.	DP=10;AF1=1;CI95=1,1;DP4=0,0,6,4;MQ=36;FQ=-57	GT:PL:GQ	1/1:131,30,0:57
-NT_166462	26762	.	CAA	CAAA	207	.	INDEL;DP=10;AF1=1;CI95=1,1;DP4=0,0,6,4;MQ=36;FQ=-64.5	GT:PL:GQ	1/1:248,30,0:57
-NT_166453	185	.	A	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166453	198	.	T	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166453	264	.	T	C	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-NT_166453	312	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166453	321	.	C	T	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-NT_166453	20370	.	G	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166467	12821	.	C	T	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-NT_166338	16706	.	C	A	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-NT_166338	16707	.	T	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166338	16708	.	C	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166338	16774	.	G	C	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-NT_166442	37512	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166442	37558	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166442	37567	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166451	487	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166450	27330	.	T	A	28	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,0,3;MQ=33;FQ=-36	GT:PL:GQ	1/1:60,9,0:16
-NT_166450	27339	.	T	C	51	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,0,3;MQ=33;FQ=-36	GT:PL:GQ	1/1:83,9,0:16
-NT_166450	27452	.	G	A	101	.	DP=11;AF1=1;CI95=1,1;DP4=0,0,6,4;MQ=37;FQ=-57	GT:PL:GQ	1/1:134,30,0:57
-NT_166450	27483	.	T	C	67.3	.	DP=7;AF1=1;CI95=0.5,1;DP4=0,0,3,2;MQ=37;FQ=-42	GT:PL:GQ	1/1:100,15,0:27
-NT_166450	27488	.	T	G	7.59	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-33	GT:PL:GQ	1/1:38,6,0:7
-NT_166450	27538	.	A	G	12	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=25;FQ=-33	GT:PL:GQ	1/1:43,6,0:9
-NT_166450	27561	.	T	C	48.1	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,2,4;MQ=27;FQ=-45	GT:PL:GQ	1/1:81,18,0:33
-NT_166450	27591	.	T	C	54.1	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,2,4;MQ=27;FQ=-45	GT:PL:GQ	1/1:87,18,0:33
-NT_166450	27618	.	T	C	77.1	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,2,4;MQ=27;FQ=-45	GT:PL:GQ	1/1:110,18,0:33
-NT_166450	27627	.	A	G	102	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,2,4;MQ=27;FQ=-45	GT:PL:GQ	1/1:135,18,0:33
-NT_166450	27651	.	G	A	10.2	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:41,6,0:8
-NT_166450	27659	.	C	A	65	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=37;FQ=-36	GT:PL:GQ	1/1:97,9,0:16
-NT_166450	27664	.	T	C	31.5	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,3,1;MQ=37;FQ=-39	GT:PL:GQ	1/1:64,12,0:21
-NT_166450	27700	.	T	C	106	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,5,3;MQ=37;FQ=-51	GT:PL:GQ	1/1:139,24,0:45
-NT_166450	27798	.	C	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166450	27807	.	T	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166450	27813	.	A	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166447	29896	.	A	G	4.77	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-NT_166468	8984	.	G	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166468	8986	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166468	8989	.	G	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166477	2080	.	T	A	3.02	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:30,3,0:4
-NT_166455	23979	.	C	A	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-NT_166291	4663	.	G	A	11.1	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:42,6,0:9
-NT_166291	4684	.	C	G	32.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:64,6,0:10
-NT_166291	27578	.	G	A	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-NT_166291	35549	.	C	G	117	.	DP=10;AF1=1;CI95=1,1;DP4=0,0,6,4;MQ=36;FQ=-57	GT:PL:GQ	1/1:150,30,0:57
-NT_166291	35756	.	A	G	198	.	DP=20;AF1=1;CI95=1,1;DP4=0,0,9,10;MQ=37;FQ=-84	GT:PL:GQ	1/1:231,57,0:99
-NT_166463	6735	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166463	6736	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166309	64876	.	A	G	25	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=33;FQ=-36	GT:PL:GQ	1/1:57,9,0:15
-NT_166309	64910	.	A	C	30.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,5,0;MQ=30;FQ=-42	GT:PL:GQ	1/1:63,15,0:27
-NT_166309	64925	.	A	G	29.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,5,0;MQ=30;FQ=-42	GT:PL:GQ	1/1:62,15,0:27
-NT_166309	64960	.	T	G	45.5	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,4,0;MQ=28;FQ=-39	GT:PL:GQ	1/1:78,12,0:21
-NT_166309	64971	.	T	G	30	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=25;FQ=-36	GT:PL:GQ	1/1:62,9,0:16
-NT_166309	64979	.	A	C	13.9	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=25;FQ=-33	GT:PL:GQ	1/1:45,6,0:10
-NT_166309	69760	.	A	G	52	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,2;MQ=33;FQ=-36	GT:PL:GQ	1/1:84,9,0:16
-NT_166309	69765	.	T	C	42	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,1,2;MQ=33;FQ=-36	GT:PL:GQ	1/1:74,9,0:16
-NT_166309	69773	.	T	C	35	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,1,2;MQ=33;FQ=-36	GT:PL:GQ	1/1:67,9,0:16
-NT_166309	69799	.	G	C	25	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,1,2;MQ=33;FQ=-36	GT:PL:GQ	1/1:57,9,0:15
-NT_166309	69869	.	T	C	35.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-33	GT:PL:GQ	1/1:67,6,0:10
-NT_166309	103113	.	T	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166309	139729	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166282	41545	.	C	T	3.02	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:30,3,0:4
-NT_166282	94999	.	C	T	31.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,3;MQ=37;FQ=-39	GT:PL:GQ	1/1:64,12,0:21
-NT_166282	95050	.	T	G	33	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,1,2;MQ=37;FQ=-36	GT:PL:GQ	1/1:65,9,0:16
-NT_166314	112573	.	C	A	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-NT_166314	118593	.	C	T	35.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,0,4;MQ=34;FQ=-39	GT:PL:GQ	1/1:68,12,0:21
-NT_166314	118608	.	C	T	73.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,0,4;MQ=34;FQ=-39	GT:PL:GQ	1/1:106,12,0:21
-NT_166314	118836	.	A	C	84.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,3;MQ=37;FQ=-39	GT:PL:GQ	1/1:117,12,0:21
-NT_166314	118924	.	G	C	212	.	DP=10;AF1=1;CI95=1,1;DP4=0,0,3,7;MQ=37;FQ=-57	GT:PL:GQ	1/1:245,30,0:57
-NT_166314	144387	.	A	T	3.54	.	DP=2;AF1=0.5001;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=-3.07;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,29:29
-NT_166314	155508	.	A	T	65.1	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,3,3;MQ=37;FQ=-45	GT:PL:GQ	1/1:98,18,0:33
-NT_112000	52371	.	G	T	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-NT_112000	52375	.	A	C	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-NT_110857	19739	.	A	G	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-NT_166280	4649	.	C	A	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-NT_166280	137528	.	T	C	32.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-33	GT:PL:GQ	1/1:64,6,0:10
-NT_166280	137545	.	C	T	13.9	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-33	GT:PL:GQ	1/1:45,6,0:10
-NT_166311	1782	.	C	T	3.02	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:30,3,0:4
-NT_166311	69821	.	G	A	65.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,4,1;MQ=33;FQ=-42	GT:PL:GQ	1/1:98,15,0:27
-NT_166311	69841	.	C	A	42.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,4,1;MQ=33;FQ=-42	GT:PL:GQ	1/1:75,15,0:27
-NT_166311	69894	.	T	G	26	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=37;FQ=-36	GT:PL:GQ	1/1:58,9,0:16
-NT_166311	69917	.	G	A	20	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=37;FQ=-36	GT:PL:GQ	1/1:52,9,0:15
-NT_166310	83175	.	C	G	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-NT_166438	13070	.	C	A	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-NT_162750	40051	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_162750	40058	.	A	G	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-NT_162750	71153	.	C	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_162750	71157	.	T	G	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-NT_166387	1835	.	C	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166281	28467	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166281	28468	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166313	178838	.	G	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166313	179067	.	C	T	3.01	.	DP=2;AF1=0.4999;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=3.25;PV4=1,1,1,1	GT:PL:GQ	0/1:30,0,31:28
-NT_166313	179084	.	T	C	3.54	.	DP=2;AF1=0.5001;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=-3.07;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,29:29
-NT_166313	179560	.	A	G	97	.	DP=6;AF1=0.5032;CI95=0.5,0.5;DP4=1,0,1,4;MQ=35;FQ=-8.63;PV4=0.33,0.019,0.35,1	GT:PL:GQ	0/1:127,0,19:22
-NT_166313	179573	.	A	T	76.1	.	DP=7;AF1=1;CI95=0.5,1;DP4=0,0,2,4;MQ=35;FQ=-45	GT:PL:GQ	1/1:109,18,0:33
-NT_166313	179575	.	C	T	68	.	DP=7;AF1=0.5;CI95=0.5,0.5;DP4=1,1,1,4;MQ=36;FQ=26;PV4=1,0.0056,0.29,1	GT:PL:GQ	0/1:98,0,53:56
-NT_166313	179587	.	A	G	42	.	DP=8;AF1=0.5;CI95=0.5,0.5;DP4=1,2,1,4;MQ=36;FQ=42.9;PV4=1,0.0032,0.24,1	GT:PL:GQ	0/1:72,0,74:73
-NT_166313	180199	.	A	G	64	.	DP=13;AF1=0.5;CI95=0.5,0.5;DP4=9,0,3,1;MQ=37;FQ=67;PV4=0.31,1,1,1	GT:PL:GQ	0/1:94,0,143:97
-NT_166313	180204	.	C	T	17.1	.	DP=14;AF1=0.5;CI95=0.5,0.5;DP4=9,0,3,1;MQ=37;FQ=20.1;PV4=0.31,5.5e-06,1,1	GT:PL:GQ	0/1:47,0,143:50
-NT_166313	180258	.	C	G	38	.	DP=19;AF1=0.5;CI95=0.5,0.5;DP4=12,2,2,2;MQ=36;FQ=41;PV4=0.2,0.37,0.029,1	GT:PL:GQ	0/1:68,0,212:71
-NT_166313	180274	.	A	G	45	.	DP=14;AF1=0.5;CI95=0.5,0.5;DP4=5,0,3,6;MQ=36;FQ=47.6;PV4=0.031,2.3e-05,0.15,1	GT:PL:GQ	0/1:75,0,85:78
-NT_166313	180300	.	A	T	11.3	.	DP=15;AF1=0.5;CI95=0.5,0.5;DP4=4,6,1,4;MQ=36;FQ=14.2;PV4=0.6,1.7e-08,1,1	GT:PL:GQ	0/1:41,0,208:43
-NT_166313	180331	.	C	T	189	.	DP=17;AF1=0.5;CI95=0.5,0.5;DP4=1,3,6,6;MQ=34;FQ=59;PV4=0.58,0.16,0.068,1	GT:PL:GQ	0/1:219,0,86:89
-NT_166313	180352	.	C	T	126	.	DP=17;AF1=0.5;CI95=0.5,0.5;DP4=5,5,3,4;MQ=34;FQ=129;PV4=1,1,1,1	GT:PL:GQ	0/1:156,0,196:99
-NT_166313	180384	.	G	A	93	.	DP=16;AF1=0.5;CI95=0.5,0.5;DP4=2,4,6,4;MQ=34;FQ=95.9;PV4=0.61,3.3e-10,0.041,1	GT:PL:GQ	0/1:123,0,141:99
-NT_166313	180748	.	A	C	18.1	.	DP=7;AF1=0.5;CI95=0.5,0.5;DP4=4,1,2,0;MQ=37;FQ=21;PV4=1,1,1,0.13	GT:PL:GQ	0/1:48,0,123:51
-NT_166313	180901	.	A	G	86.5	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,1,3;MQ=37;FQ=-39	GT:PL:GQ	1/1:119,12,0:21
-NT_166313	182411	.	T	G	5.46	.	DP=6;AF1=0.4999;CI95=0.5,0.5;DP4=3,0,0,3;MQ=35;FQ=7.8;PV4=0.1,0.0036,0.19,1	GT:PL:GQ	0/1:34,0,72:34
-NT_166313	182447	.	A	G	10.4	.	DP=5;AF1=0.5;CI95=0.5,0.5;DP4=2,0,0,3;MQ=35;FQ=13;PV4=0.1,0.014,0.25,0.14	GT:PL:GQ	0/1:40,0,53:42
-NT_166313	183242	.	C	A	3.02	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:30,3,0:4
-NT_166313	184154	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166313	184175	.	G	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166313	184807	.	T	C	15.9	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:47,6,0:10
-NT_166313	184892	.	T	G	38.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:70,6,0:10
-NT_166313	184925	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166313	184960	.	T	C	11.1	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-33	GT:PL:GQ	1/1:42,6,0:9
-NT_166313	184966	.	C	A	11.1	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-33	GT:PL:GQ	1/1:42,6,0:9
-NT_166313	185022	.	C	T	9.31	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-33	GT:PL:GQ	1/1:40,6,0:8
-NT_166313	185114	.	G	A	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-NT_166313	185707	.	TGGGGGG	TGGGG	53.4	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=37;FQ=-43.5	GT:PL:GQ	1/1:93,9,0:16
-NT_166313	186575	.	T	C	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-NT_166313	188906	.	G	C	3.02	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:30,3,0:4
-NT_166313	189753	.	T	G	42	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=37;FQ=-36	GT:PL:GQ	1/1:74,9,0:16
-NT_166313	189763	.	G	A	38	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=37;FQ=-36	GT:PL:GQ	1/1:70,9,0:16
-NT_166313	190763	.	A	C	7.59	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=32;FQ=-33	GT:PL:GQ	1/1:38,6,0:7
-NT_166313	190780	.	T	C	5.29	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=32;FQ=-33	GT:PL:GQ	1/1:35,6,0:6
-NT_166313	191046	.	C	T	33.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-33	GT:PL:GQ	1/1:65,6,0:10
-NT_166313	191075	.	C	G	32.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-33	GT:PL:GQ	1/1:64,6,0:10
-NT_166313	206710	.	CGAGAGAGAGAGAGAGAGA	CGAGAGAGAGAGAGAGA	8.18	.	INDEL;DP=8;AF1=0.5;CI95=0.5,0.5;DP4=4,2,2,0;MQ=37;FQ=10.8;PV4=1,1.5e-06,1,1	GT:PL:GQ	0/1:45,0,159:47
-NT_166313	212911	.	C	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166313	242335	.	A	T	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-NT_166313	242381	.	G	C	3.54	.	DP=3;AF1=0.5;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-NT_166313	243035	.	G	T	8.44	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=25;FQ=-33	GT:PL:GQ	1/1:39,6,0:8
-NT_166313	243084	.	A	T	18.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=25;FQ=-33	GT:PL:GQ	1/1:50,6,0:10
-NT_166313	243235	.	T	A	13.9	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-33	GT:PL:GQ	1/1:45,6,0:10
-NT_166313	243340	.	C	G	15.1	.	DP=3;AF1=0.5008;CI95=0.5,0.5;DP4=1,0,2,0;MQ=37;FQ=-4.14;PV4=1,0.3,1,0.077	GT:PL:GQ	0/1:45,0,25:28
-NT_161928	42786	.	C	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166378	24751	.	T	C	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-NT_166378	24753	.	C	T	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-NT_161926	91391	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_161926	91392	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166385	319808	.	G	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_165789	268949	.	A	G	130	.	DP=11;AF1=1;CI95=1,1;DP4=0,0,5,5;MQ=33;FQ=-57	GT:PL:GQ	1/1:163,30,0:57
-NT_165789	268956	.	T	G	133	.	DP=11;AF1=1;CI95=1,1;DP4=0,0,5,5;MQ=33;FQ=-57	GT:PL:GQ	1/1:166,30,0:57
-NT_165789	268973	.	G	A	102	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,4,4;MQ=32;FQ=-51	GT:PL:GQ	1/1:135,24,0:45
-NT_165789	269002	.	G	A	47.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,3,1;MQ=25;FQ=-39	GT:PL:GQ	1/1:80,12,0:21
-NT_165789	269016	.	C	T	38	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=25;FQ=-36	GT:PL:GQ	1/1:70,9,0:16
-NT_165789	269124	.	T	A	53.2	.	DP=9;AF1=0.5263;CI95=0.5,1;DP4=0,1,3,5;MQ=33;FQ=-17.1;PV4=1,5.2e-06,0.26,0.24	GT:PL:GQ	0/1:83,0,10:13
-NT_165789	269148	.	A	G	9.53	.	DP=5;AF1=0.5008;CI95=0.5,0.5;DP4=0,1,2,1;MQ=28;FQ=-4.22;PV4=1,0.0014,0,0.27	GT:PL:GQ	0/1:39,0,25:29
-NT_165789	269163	.	G	T	7.8	.	DP=3;AF1=0.5003;CI95=0.5,0.5;DP4=0,1,2,0;MQ=30;FQ=3.27;PV4=0.33,0.071,0,0.13	GT:PL:GQ	0/1:37,0,28:32
-NT_165789	303609	.	T	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166361	150408	.	G	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166348	244139	.	T	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166348	244145	.	G	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166369	123725	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166417	80615	.	C	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166417	80639	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166383	378092	.	T	A	5.46	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:34,3,0:3
-NT_166362	238907	.	T	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166362	238908	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_165754	250017	.	A	G	190	.	DP=22;AF1=1;CI95=1,1;DP4=0,0,11,8;MQ=37;FQ=-84	GT:PL:GQ	1/1:223,57,0:99
-NT_165754	252055	.	T	A	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-NT_165754	293702	.	G	C	6.79	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-33	GT:PL:GQ	1/1:37,6,0:7
-NT_165754	300330	.	C	A	139	.	DP=21;AF1=1;CI95=1,1;DP4=0,0,18,3;MQ=37;FQ=-90	GT:PL:GQ	1/1:172,63,0:99
-NT_165754	300742	.	AGG	AGGG	3.8	.	INDEL;DP=19;AF1=0.5;CI95=0.5,0.5;DP4=2,7,3,0;MQ=37;FQ=5.8;PV4=0.045,0.32,1,1	GT:PL:GQ	0/1:39,0,152:38
-NT_165754	300745	.	T	G	10.4	.	DP=19;AF1=0.5;CI95=0.5,0.5;DP4=0,7,5,0;MQ=35;FQ=13.2;PV4=0.0013,1.1e-06,0.038,1	GT:PL:GQ	0/1:40,0,128:42
-NT_165754	304284	.	T	TC	12.7	.	INDEL;DP=6;AF1=0.5;CI95=0.5,0.5;DP4=1,2,2,0;MQ=37;FQ=15.6;PV4=0.4,1,1,0.41	GT:PL:GQ	0/1:50,0,89:53
-NT_165754	309950	.	A	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_165754	311521	.	A	AT	6.36	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=32;FQ=-40.5	GT:PL:GQ	1/1:44,6,0:7
-NT_165754	329690	.	N	T	7.59	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-33	GT:PL:GQ	1/1:38,6,0:7
-NT_165754	329691	.	N	G	7.59	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-33	GT:PL:GQ	1/1:38,6,0:7
-NT_165754	329692	.	N	A	6.79	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-33	GT:PL:GQ	1/1:37,6,0:7
-NT_165754	329693	.	N	C	26	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,0,3;MQ=37;FQ=-36	GT:PL:GQ	1/1:58,9,0:16
-NT_165754	338325	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_161924	260016	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_165795	433385	.	G	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166370	455714	.	T	G	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-NT_166424	307990	.	T	A	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-NT_161877	518452	.	G	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_161877	518454	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166351	468564	.	A	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166408	488033	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166408	562716	.	A	G	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-NT_166349	214066	.	A	G	3.02	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:30,3,0:4
-NT_166349	214070	.	T	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166391	47103	.	C	T	5.46	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:34,3,0:3
-NT_165790	96824	.	T	G	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-NT_165790	96827	.	A	T	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-NT_166344	657504	.	A	C	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-NT_166371	140475	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_166371	140477	.	A	C	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-NT_166371	140491	.	C	A	5.46	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:34,3,0:3
-NT_161895	283625	.	A	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_161895	744483	.	C	G	38	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,0,3;MQ=33;FQ=-36	GT:PL:GQ	1/1:70,9,0:16
-NT_166404	51731	.	A	T	3.55	.	DP=2;AF1=0.5004;CI95=0.5,0.5;DP4=0,1,1,0;MQ=37;FQ=-4.23;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,26:28
-NT_161875	219900	.	G	A	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-NT_161875	219903	.	T	C	3.02	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:30,3,0:4
-NT_161866	49262	.	C	G	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-NT_161866	49264	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_161866	49265	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_161872	293963	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_161872	616242	.	T	A	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-NT_161872	714587	.	C	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_161902	401831	.	T	C	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-NT_161902	923924	.	G	A	10.2	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=32;FQ=-33	GT:PL:GQ	1/1:41,6,0:8
-NT_161937	232325	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_161937	232331	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_161937	310786	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-NT_161937	1343395	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-Y	356986	.	A	G	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-Y	362133	.	G	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-Y	372541	.	G	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-Y	385312	.	A	G	4.61	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-33	GT:PL:GQ	1/1:34,6,0:5
-Y	385313	.	A	G	4.61	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-33	GT:PL:GQ	1/1:34,6,0:5
-Y	472032	.	A	G	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-Y	503298	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-Y	529936	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-Y	534673	.	T	C	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-Y	601401	.	C	CAG	24.5	.	INDEL;DP=10;AF1=0.5;CI95=0.5,0.5;DP4=5,1,2,1;MQ=37;FQ=27.5;PV4=1,0.061,1,0.00024	GT:PL:GQ	0/1:62,0,144:65
-Y	602418	.	T	TGC	21.3	.	INDEL;DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:60,6,0:10
-Y	1448653	.	A	T	3.02	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:30,3,0:4
-Y	2564922	.	C	G	4.61	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=25;FQ=-33	GT:PL:GQ	1/1:34,6,0:5
-Y	2564933	.	A	T	5.29	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=25;FQ=-33	GT:PL:GQ	1/1:35,6,0:6
-Y	2564937	.	T	C	4.61	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=25;FQ=-33	GT:PL:GQ	1/1:34,6,0:5
-Y	2884117	.	T	C	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	3205820	.	G	A	158	.	DP=20;AF1=1;CI95=1,1;DP4=0,0,9,9;MQ=36;FQ=-81	GT:PL:GQ	1/1:191,54,0:99
-19	3205836	.	A	G	220	.	DP=36;AF1=1;CI95=1,1;DP4=0,0,20,14;MQ=37;FQ=-129	GT:PL:GQ	1/1:253,102,0:99
-19	3205943	.	G	C	152	.	DP=21;AF1=1;CI95=1,1;DP4=0,0,8,10;MQ=37;FQ=-81	GT:PL:GQ	1/1:185,54,0:99
-19	3205957	.	G	C	80.1	.	DP=8;AF1=1;CI95=0.5,1;DP4=0,0,2,4;MQ=37;FQ=-45	GT:PL:GQ	1/1:113,18,0:33
-19	3205995	.	T	C	67	.	DP=18;AF1=1;CI95=1,1;DP4=0,0,1,13;MQ=32;FQ=-69	GT:PL:GQ	1/1:100,42,0:81
-19	3206052	.	A	G	120	.	DP=12;AF1=1;CI95=1,1;DP4=0,0,3,7;MQ=34;FQ=-57	GT:PL:GQ	1/1:153,30,0:57
-19	3206060	.	T	A	71.1	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,3,3;MQ=33;FQ=-45	GT:PL:GQ	1/1:104,18,0:33
-19	3206638	.	T	G	55.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,4,1;MQ=25;FQ=-42	GT:PL:GQ	1/1:88,15,0:27
-19	3206671	.	T	C	53.4	.	DP=6;AF1=0.5554;CI95=0.5,1;DP4=1,0,4,1;MQ=25;FQ=-20;PV4=1,0.38,1,1	GT:PL:GQ	0/1:83,0,7:10
-19	3206673	.	T	C	23	.	DP=6;AF1=0.5;CI95=0.5,0.5;DP4=3,0,2,1;MQ=25;FQ=18.3;PV4=1,0.39,1,1	GT:PL:GQ	0/1:53,0,46:48
-19	3206703	.	G	A	64.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,4,1;MQ=25;FQ=-42	GT:PL:GQ	1/1:97,15,0:27
-19	3281904	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	3352482	.	C	A	32.5	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,0,4;MQ=34;FQ=-39	GT:PL:GQ	1/1:65,12,0:21
-19	3356313	.	AC	ACC	39.5	.	INDEL;DP=4;AF1=0.5016;CI95=0.5,0.5;DP4=1,0,0,3;MQ=37;FQ=-12.8;PV4=0.25,1,1,0.27	GT:PL:GQ	0/1:77,0,22:25
-19	3362225	.	A	G	23	.	DP=5;AF1=0.5016;CI95=0.5,0.5;DP4=1,0,4,0;MQ=35;FQ=-6.18;PV4=1,0.014,0.34,0.022	GT:PL:GQ	0/1:53,0,22:25
-19	3365671	.	AC	A	3.81	.	INDEL;DP=4;AF1=0.5004;CI95=0.5,0.5;DP4=0,1,1,1;MQ=37;FQ=-7.67;PV4=1,0.16,1,0.012	GT:PL:GQ	0/1:39,0,28:33
-19	3369050	.	G	GA	9.71	.	INDEL;DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:48,6,0:8
-19	3371339	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	3375209	.	A	AT	54	.	INDEL;DP=4;AF1=1;CI95=0.5,1;DP4=0,0,4,0;MQ=37;FQ=-46.5	GT:PL:GQ	1/1:94,12,0:21
-19	3457052	.	CT	CTTT	4.42	.	INDEL;DP=8;AF1=0.5;CI95=0.5,0.5;DP4=2,0,2,0;MQ=34;FQ=6.48;PV4=1,0.051,0.21,0.38	GT:PL:GQ	0/1:40,0,56:40
-19	3462257	.	T	C	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-19	3490405	.	T	A	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	3490564	.	C	G	15.1	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=37;FQ=-36	GT:PL:GQ	1/1:47,9,0:14
-19	3547993	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	3582830	.	T	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	3586482	.	T	G	58	.	DP=12;AF1=0.5;CI95=0.5,0.5;DP4=2,0,7,1;MQ=34;FQ=12.3;PV4=1,0.00069,0.18,1	GT:PL:GQ	0/1:88,0,39:42
-19	3586484	.	A	C	56	.	DP=12;AF1=0.5001;CI95=0.5,0.5;DP4=2,0,7,1;MQ=34;FQ=9.53;PV4=1,0.0044,0.18,1	GT:PL:GQ	0/1:86,0,36:39
-19	3591114	.	CTGTG	CTG	47.5	.	INDEL;DP=5;AF1=0.5016;CI95=0.5,0.5;DP4=0,1,4,0;MQ=37;FQ=-12.8;PV4=0.2,0.12,1,0.25	GT:PL:GQ	0/1:85,0,22:25
-19	3591123	.	T	G	11.3	.	DP=3;AF1=0.5004;CI95=0.5,0.5;DP4=0,1,2,0;MQ=37;FQ=3.43;PV4=0.33,0,1,0.17	GT:PL:GQ	0/1:41,0,28:31
-19	3591876	.	C	G	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	3596029	.	GACACACACACACACA	GACACACACACACA	15.6	.	INDEL;DP=7;AF1=0.5;CI95=0.5,0.5;DP4=2,1,2,0;MQ=37;FQ=18.5;PV4=1,7.9e-05,1,1	GT:PL:GQ	0/1:53,0,90:56
-19	3596048	.	TCACACACACACACACA	TCACACACACACACA	35.2	.	INDEL;DP=7;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:74,6,0:10
-19	3610237	.	CG	CGGG	28.2	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:67,6,0:10
-19	3612197	.	CGG	CGGG	12.7	.	INDEL;DP=3;AF1=0.5013;CI95=0.5,0.5;DP4=1,0,1,1;MQ=33;FQ=-11.8;PV4=1,0.43,0.33,0.33	GT:PL:GQ	0/1:50,0,23:26
-19	3615652	.	C	G	7.8	.	DP=5;AF1=0.5003;CI95=0.5,0.5;DP4=0,1,0,2;MQ=33;FQ=3.27;PV4=1,0.046,0.33,0.32	GT:PL:GQ	0/1:37,0,28:32
-19	3621243	.	A	G	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	3647660	.	C	A	3.41	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-33	GT:PL:GQ	1/1:32,6,0:4
-19	3649602	.	T	G	41.5	.	DP=9;AF1=1;CI95=0.5,1;DP4=0,0,4,0;MQ=32;FQ=-39	GT:PL:GQ	1/1:74,12,0:21
-19	3649604	.	C	A	26	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=33;FQ=-36	GT:PL:GQ	1/1:58,9,0:16
-19	3649607	.	T	G	31.5	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,4,0;MQ=32;FQ=-39	GT:PL:GQ	1/1:64,12,0:21
-19	3673470	.	G	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	3682731	.	T	G	3.02	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:30,3,0:4
-19	3784152	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	3817931	.	A	T	17.1	.	DP=10;AF1=0.5;CI95=0.5,0.5;DP4=1,6,1,1;MQ=37;FQ=20.1;PV4=0.42,1,1,7.9e-09	GT:PL:GQ	0/1:47,0,150:50
-19	3885854	.	TT	TTAT	8.18	.	INDEL;DP=4;AF1=0.5;CI95=0.5,0.5;DP4=0,2,0,2;MQ=37;FQ=10.5;PV4=1,0.26,1,0.36	GT:PL:GQ	0/1:45,0,56:46
-19	3897463	.	C	CA	23.5	.	INDEL;DP=12;AF1=0.5;CI95=0.5,0.5;DP4=4,3,0,4;MQ=37;FQ=26.5;PV4=0.19,0.02,1,2.5e-05	GT:PL:GQ	0/1:61,0,178:64
-19	3899540	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	3903173	.	C	T	3.01	.	DP=13;AF1=0.4997;CI95=0.5,0.5;DP4=4,4,3,0;MQ=36;FQ=4.77;PV4=0.24,0.028,0.052,1	GT:PL:GQ	0/1:30,0,163:28
-19	3903429	.	CTA	C	31.5	.	INDEL;DP=11;AF1=0.5;CI95=0.5,0.5;DP4=4,2,3,0;MQ=37;FQ=34.5;PV4=0.5,1.4e-09,1,1	GT:PL:GQ	0/1:69,0,157:72
-19	3903506	.	G	GCC	30.5	.	INDEL;DP=7;AF1=0.5;CI95=0.5,0.5;DP4=1,2,0,3;MQ=35;FQ=33.4;PV4=1,1,0.19,1	GT:PL:GQ	0/1:68,0,87:71
-19	3909282	.	CTG	CTGTG	22.5	.	INDEL;DP=6;AF1=0.5004;CI95=0.5,0.5;DP4=0,1,1,1;MQ=37;FQ=-7.4;PV4=1,0.4,1,0.33	GT:PL:GQ	0/1:60,0,28:31
-19	3909704	.	A	T	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	3909837	.	T	C	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	3937591	.	G	A	4.61	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-33	GT:PL:GQ	1/1:34,6,0:5
-19	3944020	.	TA	T	6.55	.	INDEL;DP=3;AF1=0.5004;CI95=0.5,0.5;DP4=0,1,1,1;MQ=33;FQ=-7.51;PV4=1,0.28,0.33,0	GT:PL:GQ	0/1:43,0,28:33
-19	3955855	.	T	G	3.02	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:30,3,0:4
-19	4012679	.	A	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	4036683	.	C	CCAT	16.6	.	INDEL;DP=5;AF1=0.5;CI95=0.5,0.5;DP4=2,1,1,1;MQ=37;FQ=19.5;PV4=1,0.12,1,0.04	GT:PL:GQ	0/1:54,0,90:57
-19	4097507	.	G	GCC	45.5	.	INDEL;DP=5;AF1=0.5032;CI95=0.5,0.5;DP4=1,0,4,0;MQ=35;FQ=-15.6;PV4=1,1,0.34,0.34	GT:PL:GQ	0/1:83,0,19:22
-19	4097921	.	AG	A	16.6	.	INDEL;DP=5;AF1=0.5;CI95=0.5,0.5;DP4=0,2,2,1;MQ=35;FQ=16;PV4=0.4,0.028,0.25,0.013	GT:PL:GQ	0/1:54,0,53:53
-19	4103486	.	GT	GTCT	21.5	.	INDEL;DP=6;AF1=0.5004;CI95=0.5,0.5;DP4=0,1,2,0;MQ=37;FQ=-7.4;PV4=0.33,0.41,1,0.016	GT:PL:GQ	0/1:59,0,28:31
-19	4109610	.	A	G	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	4126040	.	GCCCCC	GCCCC	38.5	.	INDEL;DP=9;AF1=1;CI95=1,1;DP4=0,0,7,0;MQ=37;FQ=-55.5	GT:PL:GQ	1/1:79,21,0:39
-19	4128088	.	T	C	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	4150222	.	T	TG	16.6	.	INDEL;DP=9;AF1=0.5;CI95=0.5,0.5;DP4=3,3,2,1;MQ=36;FQ=19.5;PV4=1,0.35,0.085,4e-05	GT:PL:GQ	0/1:54,0,140:57
-19	4192878	.	T	TG	159	.	INDEL;DP=17;AF1=1;CI95=0.5,1;DP4=0,1,9,3;MQ=37;FQ=-40.5;PV4=0.31,0.48,1,0.4	GT:PL:GQ	1/1:198,6,0:10
-19	4192885	.	T	A	8.65	.	DP=9;AF1=0.5008;CI95=0.5,0.5;DP4=0,1,3,0;MQ=37;FQ=-4.25;PV4=0.25,0.045,1,0.44	GT:PL:GQ	0/1:38,0,25:29
-19	4193254	.	T	C	111	.	DP=9;AF1=1;CI95=1,1;DP4=0,0,5,2;MQ=32;FQ=-48	GT:PL:GQ	1/1:144,21,0:39
-19	4194973	.	CT	C	114	.	INDEL;DP=14;AF1=0.5;CI95=0.5,0.5;DP4=4,2,3,3;MQ=37;FQ=113;PV4=1,2.2e-05,1,0.018	GT:PL:GQ	0/1:152,0,150:99
-19	4218544	.	GACACACACACACACACACACAC	GACACACACACACACACACAC	20.5	.	INDEL;DP=14;AF1=0.5;CI95=0.5,0.5;DP4=0,10,0,3;MQ=37;FQ=23.5;PV4=1,0.28,1,1	GT:PL:GQ	0/1:58,0,144:61
-19	4265650	.	A	C	15.1	.	DP=8;AF1=0.5002;CI95=0.5,0.5;DP4=1,1,0,3;MQ=35;FQ=5.35;PV4=0.4,1,0.25,1	GT:PL:GQ	0/1:45,0,31:34
-19	4275479	.	A	G	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	4287266	.	TG	T	11.5	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=32;FQ=-40.5	GT:PL:GQ	1/1:50,6,0:9
-19	4288411	.	C	A	14.2	.	DP=13;AF1=0.5;CI95=0.5,0.5;DP4=4,5,1,3;MQ=36;FQ=17.1;PV4=1,0.00097,1,1	GT:PL:GQ	0/1:44,0,185:47
-19	4293399	.	G	A	3.01	.	DP=2;AF1=0.4999;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=3.25;PV4=1,1,1,1	GT:PL:GQ	0/1:30,0,31:28
-19	4293435	.	T	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	4319284	.	G	GCCA	39.4	.	INDEL;DP=4;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=33;FQ=-43.5	GT:PL:GQ	1/1:79,9,0:16
-19	4320148	.	AT	A	53.4	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=33;FQ=-43.5	GT:PL:GQ	1/1:93,9,0:16
-19	4328716	.	C	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	4356928	.	T	C	9.49	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=37;FQ=-36	GT:PL:GQ	1/1:41,9,0:12
-19	4395270	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	4397535	.	G	A	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	4616344	.	A	G	31.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:63,6,0:10
-19	4619199	.	G	GACA	28.2	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:67,6,0:10
-19	4746969	.	G	GA	21.3	.	INDEL;DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:60,6,0:10
-19	4784161	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	4785570	.	G	C	7.8	.	DP=3;AF1=0.5003;CI95=0.5,0.5;DP4=1,0,1,1;MQ=37;FQ=3.27;PV4=1,0.034,1,0.025	GT:PL:GQ	0/1:37,0,28:32
-19	4799879	.	T	C	34.8	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:66,6,0:10
-19	4888267	.	A	T	3.54	.	DP=3;AF1=0.5;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	4918151	.	CT	CTT	17.3	.	INDEL;DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:56,6,0:10
-19	4923064	.	CA	C	16.6	.	INDEL;DP=4;AF1=0.5008;CI95=0.5,0.5;DP4=0,1,1,2;MQ=34;FQ=-9.99;PV4=1,0.11,0.33,0.33	GT:PL:GQ	0/1:54,0,25:28
-19	4964673	.	G	GGA	7.98	.	INDEL;DP=4;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=32;FQ=-40.5	GT:PL:GQ	1/1:46,6,0:8
-19	5045349	.	G	GT	11.8	.	INDEL;DP=4;AF1=0.5008;CI95=0.5,0.5;DP4=1,0,1,1;MQ=37;FQ=-10;PV4=1,0.47,1,1	GT:PL:GQ	0/1:49,0,25:29
-19	5046911	.	G	GA	35.2	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:74,6,0:10
-19	5048333	.	A	G	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-19	5081755	.	G	A	20	.	DP=6;AF1=0.5;CI95=0.5,0.5;DP4=1,3,1,1;MQ=37;FQ=23;PV4=1,0.22,1,1	GT:PL:GQ	0/1:50,0,107:53
-19	5111720	.	C	CAG	28.2	.	INDEL;DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:67,6,0:10
-19	5113937	.	TC	TCC	21.3	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:60,6,0:10
-19	5116885	.	T	A	3.01	.	DP=2;AF1=0.4999;CI95=0.5,0.5;DP4=0,1,1,0;MQ=37;FQ=3.25;PV4=1,1,1,1	GT:PL:GQ	0/1:30,0,31:28
-19	5140839	.	T	A	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	5142716	.	T	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	5152822	.	T	TC	77.5	.	INDEL;DP=8;AF1=0.5064;CI95=0.5,0.5;DP4=1,0,6,0;MQ=37;FQ=-18.6;PV4=1,0.48,1,0.0022	GT:PL:GQ	0/1:115,0,16:19
-19	5152825	.	A	C	3.02	.	DP=6;AF1=0.5001;CI95=0.5,0.5;DP4=1,0,2,0;MQ=37;FQ=-3.6;PV4=1,0.057,1,0.052	GT:PL:GQ	0/1:30,0,28:28
-19	5154577	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	5226915	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	5245293	.	G	A	5.46	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:34,3,0:3
-19	5245305	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	5264850	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	5274427	.	T	C	3.01	.	DP=54;AF1=0.4997;CI95=0.5,0.5;DP4=22,18,6,5;MQ=37;FQ=4.77;PV4=1,1e-18,1,1	GT:PL:GQ	0/1:30,0,255:28
-19	5274978	.	C	CG	99.7	.	INDEL;DP=10;AF1=1;CI95=0.5,1;DP4=0,0,4,1;MQ=37;FQ=-49.5	GT:PL:GQ	1/1:140,15,0:27
-19	5275059	.	C	CA	30.2	.	INDEL;DP=6;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:69,6,0:10
-19	5279268	.	C	CTT	40.5	.	INDEL;DP=5;AF1=0.5008;CI95=0.5,0.5;DP4=1,0,3,0;MQ=37;FQ=-9.98;PV4=1,0.46,1,0.0034	GT:PL:GQ	0/1:78,0,25:28
-19	5279373	.	GT	GTCT	115	.	INDEL;DP=11;AF1=0.5263;CI95=0.5,1;DP4=1,0,7,1;MQ=35;FQ=-24.5;PV4=1,1,0.31,0.44	GT:PL:GQ	0/1:152,0,10:13
-19	5279469	.	C	CG	12.7	.	INDEL;DP=6;AF1=0.5;CI95=0.5,0.5;DP4=1,1,0,3;MQ=35;FQ=13.9;PV4=0.4,0.027,0.25,0.25	GT:PL:GQ	0/1:50,0,53:51
-19	5293078	.	A	G	3.02	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:30,3,0:4
-19	5293322	.	A	G	22	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=37;FQ=-36	GT:PL:GQ	1/1:54,9,0:15
-19	5299338	.	T	C	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-19	5324189	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	5324197	.	C	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	5324249	.	G	C	5.29	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-33	GT:PL:GQ	1/1:35,6,0:6
-19	5325094	.	T	C	12	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=32;FQ=-33	GT:PL:GQ	1/1:43,6,0:9
-19	5325106	.	A	G	25.8	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=32;FQ=-33	GT:PL:GQ	1/1:57,6,0:10
-19	5325161	.	T	C	75.1	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,2,4;MQ=35;FQ=-45	GT:PL:GQ	1/1:108,18,0:33
-19	5334753	.	G	A	122	.	DP=10;AF1=1;CI95=1,1;DP4=0,0,3,7;MQ=29;FQ=-57	GT:PL:GQ	1/1:155,30,0:57
-19	5334800	.	G	C	101	.	DP=9;AF1=1;CI95=1,1;DP4=0,0,2,7;MQ=28;FQ=-54	GT:PL:GQ	1/1:134,27,0:51
-19	5334810	.	T	C	29	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,1,2;MQ=25;FQ=-36	GT:PL:GQ	1/1:61,9,0:16
-19	5371182	.	ATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT	ATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT	28.5	.	INDEL;DP=11;AF1=0.5;CI95=0.5,0.5;DP4=1,4,0,3;MQ=37;FQ=31.5;PV4=1,0.24,1,0.4	GT:PL:GQ	0/1:66,0,107:69
-19	5415628	.	A	G	58.2	.	DP=5;AF1=0.5207;CI95=0.5,1;DP4=0,1,2,2;MQ=30;FQ=-16.1;PV4=1,1,0.14,1	GT:PL:GQ	0/1:88,0,11:14
-19	5415652	.	C	G	19.1	.	DP=5;AF1=0.5;CI95=0.5,0.5;DP4=0,2,1,2;MQ=33;FQ=16.7;PV4=1,0.0019,0.11,1	GT:PL:GQ	0/1:49,0,45:47
-19	5415658	.	A	T	35	.	DP=5;AF1=0.5;CI95=0.5,0.5;DP4=0,2,1,2;MQ=33;FQ=15.1;PV4=1,1,0.11,1	GT:PL:GQ	0/1:65,0,42:45
-19	5415664	.	G	A	14.2	.	DP=5;AF1=0.5;CI95=0.5,0.5;DP4=0,2,1,2;MQ=33;FQ=16.1;PV4=1,0.0034,0.11,1	GT:PL:GQ	0/1:44,0,50:46
-19	5423558	.	A	AT	121	.	INDEL;DP=15;AF1=1;CI95=1,1;DP4=0,0,0,9;MQ=37;FQ=-61.5	GT:PL:GQ	1/1:162,27,0:51
-19	5424274	.	GG	GGAG	46.5	.	INDEL;DP=12;AF1=0.5;CI95=0.5,0.5;DP4=2,3,4,1;MQ=37;FQ=49.5;PV4=0.52,0.014,1,1	GT:PL:GQ	0/1:84,0,134:87
-19	5426086	.	A	C	14.2	.	DP=33;AF1=0.5;CI95=0.5,0.5;DP4=15,2,0,9;MQ=37;FQ=17.1;PV4=1.8e-05,1.7e-09,1,1	GT:PL:GQ	0/1:44,0,212:47
-19	5462528	.	A	AGG	45.4	.	INDEL;DP=5;AF1=1;CI95=0.5,1;DP4=0,0,1,2;MQ=37;FQ=-43.5	GT:PL:GQ	1/1:85,9,0:16
-19	5479300	.	C	A	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	5480150	.	G	A	7.59	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=32;FQ=-33	GT:PL:GQ	1/1:38,6,0:7
-19	5533657	.	C	G	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	5535804	.	C	T	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-19	5580726	.	C	T	3.02	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:30,3,0:4
-19	5640300	.	CA	C	77.5	.	INDEL;DP=10;AF1=0.5;CI95=0.5,0.5;DP4=1,3,1,4;MQ=37;FQ=71;PV4=1,0.049,1,0.065	GT:PL:GQ	0/1:115,0,106:99
-19	5642274	.	A	G	9.52	.	DP=10;AF1=0.5;CI95=0.5,0.5;DP4=1,6,0,3;MQ=37;FQ=12.3;PV4=1,0.0039,1,0.22	GT:PL:GQ	0/1:39,0,152:41
-19	5646794	.	C	CAA	4.42	.	INDEL;DP=11;AF1=0.5;CI95=0.5,0.5;DP4=5,2,0,4;MQ=36;FQ=6.56;PV4=0.061,0.00082,0.1,4.2e-05	GT:PL:GQ	0/1:40,0,170:40
-19	5652568	.	T	TTC	47.5	.	INDEL;DP=13;AF1=0.5;CI95=0.5,0.5;DP4=5,1,4,0;MQ=37;FQ=50.5;PV4=1,0.33,1,0.035	GT:PL:GQ	0/1:85,0,142:88
-19	5652874	.	CT	CTT	45.5	.	INDEL;DP=8;AF1=0.5;CI95=0.5,0.5;DP4=0,3,4,0;MQ=36;FQ=34.3;PV4=0.029,0.31,0.22,1	GT:PL:GQ	0/1:83,0,69:72
-19	5655793	.	T	TTTG	15.6	.	INDEL;DP=5;AF1=0.5;CI95=0.5,0.5;DP4=2,1,2,0;MQ=37;FQ=18.5;PV4=1,0.031,1,0.0029	GT:PL:GQ	0/1:53,0,90:56
-19	5671522	.	C	CT	8.18	.	INDEL;DP=8;AF1=0.5;CI95=0.5,0.5;DP4=3,1,0,2;MQ=37;FQ=10.8;PV4=0.4,0.24,1,0.028	GT:PL:GQ	0/1:45,0,113:47
-19	5673355	.	C	G	16.1	.	DP=4;AF1=0.5;CI95=0.5,0.5;DP4=0,2,1,1;MQ=37;FQ=18.7;PV4=1,0.012,1,0.00027	GT:PL:GQ	0/1:46,0,56:48
-19	5673587	.	AGCT	AGCTTGCT	15.6	.	INDEL;DP=7;AF1=0.5;CI95=0.5,0.5;DP4=0,3,2,0;MQ=37;FQ=18.5;PV4=0.1,0.4,1,0.18	GT:PL:GQ	0/1:53,0,79:56
-19	5700971	.	GT	G	13.7	.	INDEL;DP=4;AF1=0.5;CI95=0.5,0.5;DP4=2,0,0,2;MQ=37;FQ=15.4;PV4=0.33,0.057,1,0.00094	GT:PL:GQ	0/1:51,0,56:53
-19	5722189	.	A	T	15.9	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-33	GT:PL:GQ	1/1:47,6,0:10
-19	5747411	.	A	ATT	28.2	.	INDEL;DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:67,6,0:10
-19	5751303	.	G	GAC	36.5	.	INDEL;DP=8;AF1=0.5;CI95=0.5,0.5;DP4=3,1,3,0;MQ=37;FQ=39.5;PV4=1,1,1,0.0091	GT:PL:GQ	0/1:74,0,110:77
-19	5765309	.	C	T	3.02	.	DP=3;AF1=0.5001;CI95=0.5,0.5;DP4=1,0,0,2;MQ=37;FQ=-3.6;PV4=0.33,0.14,1,1	GT:PL:GQ	0/1:30,0,28:28
-19	5766155	.	T	TCCC	5.8	.	INDEL;DP=3;AF1=0.5004;CI95=0.5,0.5;DP4=1,0,0,2;MQ=37;FQ=-7.54;PV4=0.33,0.044,1,1	GT:PL:GQ	0/1:42,0,28:33
-19	5802669	.	CCT	CCTCT	23.5	.	INDEL;DP=11;AF1=0.5001;CI95=0.5,0.5;DP4=1,1,3,0;MQ=33;FQ=-3.84;PV4=0.4,1,0.11,1	GT:PL:GQ	0/1:61,0,33:36
-19	5837235	.	G	A	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	5853932	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	5894371	.	G	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	5899740	.	A	G	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	5902359	.	GT	G	20.5	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,0,3;MQ=33;FQ=-43.5	GT:PL:GQ	1/1:60,9,0:15
-19	5905108	.	G	C	3.54	.	DP=2;AF1=0.5002;CI95=0.5,0.5;DP4=0,1,1,0;MQ=37;FQ=-3.4;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,28:29
-19	5951787	.	C	T	18	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=37;FQ=-36	GT:PL:GQ	1/1:50,9,0:15
-19	5956115	.	CT	CTT	20.5	.	INDEL;DP=4;AF1=0.501;CI95=0.5,0.5;DP4=0,1,1,1;MQ=37;FQ=-10.9;PV4=1,1,1,0.33	GT:PL:GQ	0/1:58,0,24:27
-19	5956116	.	TA	T	20.5	.	INDEL;DP=4;AF1=0.5004;CI95=0.5,0.5;DP4=0,1,1,1;MQ=37;FQ=-7.4;PV4=1,0.24,1,0.31	GT:PL:GQ	0/1:58,0,28:31
-19	5988978	.	AGG	AGGGG	95	.	INDEL;DP=5;AF1=1;CI95=0.5,1;DP4=0,0,2,2;MQ=37;FQ=-46.5	GT:PL:GQ	1/1:135,12,0:21
-19	5990457	.	G	GC	48.5	.	INDEL;DP=6;AF1=0.5;CI95=0.5,0.5;DP4=2,0,2,1;MQ=37;FQ=18.5;PV4=1,1,1,0.11	GT:PL:GQ	0/1:86,0,53:56
-19	5992164	.	A	T	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-19	6011296	.	CTT	CTTT	89	.	INDEL;DP=6;AF1=1;CI95=0.5,1;DP4=0,0,1,3;MQ=37;FQ=-46.5	GT:PL:GQ	1/1:129,12,0:21
-19	6047971	.	C	T	141	.	DP=14;AF1=0.5;CI95=0.5,0.5;DP4=3,3,2,6;MQ=37;FQ=114;PV4=0.58,0.44,1,1	GT:PL:GQ	0/1:171,0,141:99
-19	6071701	.	A	T	8.64	.	DP=10;AF1=0.5;CI95=0.5,0.5;DP4=3,1,3,0;MQ=36;FQ=11.3;PV4=1,0.12,1,1	GT:PL:GQ	0/1:38,0,89:40
-19	6084061	.	CT	CTT	14.6	.	INDEL;DP=7;AF1=0.5;CI95=0.5,0.5;DP4=1,1,2,0;MQ=37;FQ=16.4;PV4=1,1,1,0.21	GT:PL:GQ	0/1:52,0,57:54
-19	6116433	.	G	T	3.01	.	DP=2;AF1=0.4999;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=3.25;PV4=1,1,1,1	GT:PL:GQ	0/1:30,0,31:28
-19	6152712	.	A	G	34	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=30;FQ=-36	GT:PL:GQ	1/1:66,9,0:16
-19	6152741	.	T	C	191	.	DP=12;AF1=1;CI95=1,1;DP4=0,0,8,3;MQ=34;FQ=-60	GT:PL:GQ	1/1:224,33,0:63
-19	6152749	.	T	C	167	.	DP=17;AF1=1;CI95=1,1;DP4=0,0,11,5;MQ=35;FQ=-75	GT:PL:GQ	1/1:200,48,0:93
-19	6152890	.	T	C	100	.	DP=7;AF1=1;CI95=1,1;DP4=0,0,3,4;MQ=37;FQ=-48	GT:PL:GQ	1/1:133,21,0:39
-19	6152982	.	G	A	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-19	6153036	.	C	T	55.5	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,2,2;MQ=37;FQ=-39	GT:PL:GQ	1/1:88,12,0:21
-19	6153077	.	C	T	222	.	DP=20;AF1=1;CI95=1,1;DP4=0,0,9,11;MQ=37;FQ=-87	GT:PL:GQ	1/1:255,60,0:99
-19	6153163	.	T	C	194	.	DP=9;AF1=1;CI95=1,1;DP4=0,0,3,6;MQ=37;FQ=-54	GT:PL:GQ	1/1:227,27,0:51
-19	6175510	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	6228939	.	CA	C	78	.	INDEL;DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,3;MQ=34;FQ=-46.5	GT:PL:GQ	1/1:118,12,0:21
-19	6230906	.	C	G	15.1	.	DP=5;AF1=0.5008;CI95=0.5,0.5;DP4=1,0,0,3;MQ=37;FQ=-4.14;PV4=0.25,0.0037,1,0.1	GT:PL:GQ	0/1:45,0,25:28
-19	6249082	.	T	C	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	6251864	.	G	GA	28.2	.	INDEL;DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:67,6,0:10
-19	6280998	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	6288939	.	C	A	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-19	6289471	.	A	G	18.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:50,6,0:10
-19	6293530	.	C	T	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	6294628	.	T	TCC	70	.	INDEL;DP=4;AF1=1;CI95=0.5,1;DP4=0,0,4,0;MQ=37;FQ=-46.5	GT:PL:GQ	1/1:110,12,0:21
-19	6313685	.	A	G	4.77	.	DP=5;AF1=0.4999;CI95=0.5,0.5;DP4=1,1,1,1;MQ=37;FQ=6.98;PV4=1,0.00041,1,0.0011	GT:PL:GQ	0/1:33,0,62:33
-19	6314781	.	G	C	44.1	.	DP=8;AF1=1;CI95=0.5,1;DP4=0,0,6,0;MQ=32;FQ=-45	GT:PL:GQ	1/1:77,18,0:33
-19	6316439	.	G	GA	11.7	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=33;FQ=-43.5	GT:PL:GQ	1/1:51,9,0:13
-19	6322372	.	G	GC	10.6	.	INDEL;DP=5;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:49,6,0:9
-19	6355840	.	C	CAG	11.8	.	INDEL;DP=5;AF1=0.5;CI95=0.5,0.5;DP4=2,1,2,0;MQ=37;FQ=14.6;PV4=1,1,1,0.45	GT:PL:GQ	0/1:49,0,85:51
-19	6363411	.	G	A	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-19	6365792	.	G	GT	47.5	.	INDEL;DP=16;AF1=0.5;CI95=0.5,0.5;DP4=6,3,4,1;MQ=37;FQ=50.5;PV4=1,0.08,1,0.055	GT:PL:GQ	0/1:85,0,201:88
-19	6365797	.	A	C	4.13	.	DP=14;AF1=0.4998;CI95=0.5,0.5;DP4=6,3,4,0;MQ=37;FQ=6.2;PV4=0.5,5.7e-06,1,0.1	GT:PL:GQ	0/1:32,0,196:31
-19	6372298	.	T	C	18	.	DP=8;AF1=1;CI95=0.5,1;DP4=0,0,0,3;MQ=33;FQ=-36	GT:PL:GQ	1/1:50,9,0:15
-19	6372626	.	G	GCC	16.6	.	INDEL;DP=8;AF1=0.5008;CI95=0.5,0.5;DP4=1,0,3,0;MQ=37;FQ=-9.99;PV4=1,0.061,1,0.0096	GT:PL:GQ	0/1:54,0,25:28
-19	6374284	.	G	A	13.2	.	DP=7;AF1=0.5016;CI95=0.5,0.5;DP4=0,1,3,1;MQ=33;FQ=-6.21;PV4=0.4,0.012,0.25,1	GT:PL:GQ	0/1:43,0,22:25
-19	6374286	.	A	C	4.13	.	DP=7;AF1=0.5006;CI95=0.5,0.5;DP4=0,1,3,0;MQ=34;FQ=-4.62;PV4=0.25,0.031,0.33,1	GT:PL:GQ	0/1:32,0,25:29
-19	6386021	.	T	TGGC	11.8	.	INDEL;DP=3;AF1=0.5004;CI95=0.5,0.5;DP4=1,0,0,2;MQ=33;FQ=-7.43;PV4=0.33,0.44,0.33,0.33	GT:PL:GQ	0/1:49,0,28:32
-19	6390455	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	6502037	.	T	G	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	6592212	.	A	G	6.02	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=32;FQ=-33	GT:PL:GQ	1/1:36,6,0:6
-19	6642108	.	C	T	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-19	6905075	.	A	AGC	7.98	.	INDEL;DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:46,6,0:8
-19	6909201	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	6915048	.	T	G	5.29	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-33	GT:PL:GQ	1/1:35,6,0:6
-19	6981442	.	CT	CTT	56.7	.	INDEL;DP=13;AF1=1;CI95=0.5,1;DP4=0,0,5,0;MQ=33;FQ=-49.5	GT:PL:GQ	1/1:97,15,0:27
-19	6986843	.	A	AG	12.7	.	INDEL;DP=5;AF1=0.5008;CI95=0.5,0.5;DP4=1,0,1,2;MQ=37;FQ=-10;PV4=1,0.13,1,0.33	GT:PL:GQ	0/1:50,0,25:28
-19	6992893	.	T	C	26	.	DP=6;AF1=0.5;CI95=0.5,0.5;DP4=2,2,1,1;MQ=37;FQ=29;PV4=1,0.27,1,0.42	GT:PL:GQ	0/1:56,0,118:59
-19	7032496	.	G	A	20.8	.	DP=6;AF1=0.6243;CI95=0.5,1;DP4=0,1,4,0;MQ=30;FQ=-23;PV4=0.2,1,0.14,0.037	GT:PL:GQ	0/1:50,0,4:7
-19	7032498	.	T	C	19.1	.	DP=5;AF1=0.501;CI95=0.5,0.5;DP4=0,1,3,0;MQ=28;FQ=-4.76;PV4=0.25,0.1,0,0.0026	GT:PL:GQ	0/1:49,0,24:27
-19	7039010	.	CT	C	30.2	.	INDEL;DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:69,6,0:10
-19	7052925	.	TCC	TCCCC	11.8	.	INDEL;DP=3;AF1=0.5004;CI95=0.5,0.5;DP4=1,0,2,0;MQ=33;FQ=-7.43;PV4=1,0.4,0.33,1	GT:PL:GQ	0/1:49,0,28:32
-19	7053458	.	CTT	CTTT	10.8	.	INDEL;DP=3;AF1=0.501;CI95=0.5,0.5;DP4=0,1,1,1;MQ=37;FQ=-10.9;PV4=1,0.17,1,0.024	GT:PL:GQ	0/1:48,0,24:28
-19	7074272	.	TA	T	4.42	.	INDEL;DP=5;AF1=0.5;CI95=0.5,0.5;DP4=1,2,2,0;MQ=37;FQ=6.56;PV4=0.4,1,1,0.099	GT:PL:GQ	0/1:40,0,90:40
-19	7096313	.	CT	CTT	28.5	.	INDEL;DP=6;AF1=0.5;CI95=0.5,0.5;DP4=1,1,2,1;MQ=37;FQ=20.2;PV4=1,0.26,1,0.06	GT:PL:GQ	0/1:66,0,55:58
-19	7108797	.	GT	G	24.2	.	INDEL;DP=5;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:63,6,0:10
-19	7109279	.	CT	CTT	63	.	INDEL;DP=4;AF1=1;CI95=0.5,1;DP4=0,0,3,1;MQ=34;FQ=-46.5	GT:PL:GQ	1/1:103,12,0:21
-19	7273732	.	G	GC	50.5	.	INDEL;DP=7;AF1=0.504;CI95=0.5,0.5;DP4=0,1,0,4;MQ=37;FQ=-16.6;PV4=1,1,1,0.0018	GT:PL:GQ	0/1:88,0,18:21
-19	7273860	.	ACCT	ACCTCCT	33.5	.	INDEL;DP=5;AF1=0.5;CI95=0.5,0.5;DP4=1,1,0,3;MQ=35;FQ=24.2;PV4=0.4,1,0.25,0.021	GT:PL:GQ	0/1:71,0,59:62
-19	7322919	.	G	C	5.46	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:34,3,0:3
-19	7351944	.	T	A	4.77	.	DP=6;AF1=0.4999;CI95=0.5,0.5;DP4=1,1,2,0;MQ=37;FQ=6.98;PV4=1,0.1,1,0.18	GT:PL:GQ	0/1:33,0,61:33
-19	7359479	.	CT	CTT	41.4	.	INDEL;DP=5;AF1=1;CI95=0.5,1;DP4=0,0,1,2;MQ=37;FQ=-43.5	GT:PL:GQ	1/1:81,9,0:16
-19	7361488	.	T	TC	8.83	.	INDEL;DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=32;FQ=-40.5	GT:PL:GQ	1/1:47,6,0:8
-19	7401873	.	A	T	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	7435993	.	G	A	3.01	.	DP=2;AF1=0.4999;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=3.25;PV4=1,1,1,1	GT:PL:GQ	0/1:30,0,31:28
-19	7446286	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	7450404	.	G	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	7451189	.	G	C	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	7459826	.	T	C	3.54	.	DP=2;AF1=0.5001;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=3.25;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,30:29
-19	7473416	.	T	C	212	.	DP=12;AF1=1;CI95=1,1;DP4=0,0,4,6;MQ=37;FQ=-57	GT:PL:GQ	1/1:245,30,0:57
-19	7533049	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	7559363	.	G	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	7596698	.	G	A	24	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=37;FQ=-36	GT:PL:GQ	1/1:56,9,0:15
-19	7609641	.	G	T	49	.	DP=25;AF1=0.5;CI95=0.5,0.5;DP4=7,3,0,10;MQ=37;FQ=52;PV4=0.0031,5.7e-05,1,0.46	GT:PL:GQ	0/1:79,0,183:82
-19	7609735	.	A	G	60	.	DP=28;AF1=0.5;CI95=0.5,0.5;DP4=11,5,5,6;MQ=37;FQ=63;PV4=0.26,2.6e-15,1,0.22	GT:PL:GQ	0/1:90,0,255:93
-19	7609740	.	A	G	141	.	DP=27;AF1=0.5;CI95=0.5,0.5;DP4=7,2,9,9;MQ=37;FQ=130;PV4=0.23,6.6e-13,1,1	GT:PL:GQ	0/1:171,0,157:99
-19	7610022	.	A	G	68	.	DP=22;AF1=0.5;CI95=0.5,0.5;DP4=6,8,3,5;MQ=37;FQ=71;PV4=1,0.013,1,1	GT:PL:GQ	0/1:98,0,225:99
-19	7612605	.	A	G	79	.	DP=43;AF1=0.5;CI95=0.5,0.5;DP4=9,19,6,7;MQ=37;FQ=82;PV4=0.49,5e-12,0.072,0.43	GT:PL:GQ	0/1:109,0,255:99
-19	7672449	.	T	C	3.54	.	DP=2;AF1=0.5001;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=3.25;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,30:29
-19	7742879	.	T	C	155	.	DP=13;AF1=1;CI95=1,1;DP4=0,0,3,10;MQ=37;FQ=-66	GT:PL:GQ	1/1:188,39,0:75
-19	7742923	.	T	C	222	.	DP=29;AF1=1;CI95=1,1;DP4=0,0,10,16;MQ=37;FQ=-105	GT:PL:GQ	1/1:255,78,0:99
-19	7742993	.	A	G	222	.	DP=39;AF1=1;CI95=1,1;DP4=0,0,24,14;MQ=37;FQ=-141	GT:PL:GQ	1/1:255,114,0:99
-19	7743097	.	G	A	222	.	DP=36;AF1=1;CI95=1,1;DP4=0,0,12,24;MQ=37;FQ=-135	GT:PL:GQ	1/1:255,108,0:99
-19	7743265	.	A	G	143	.	DP=17;AF1=1;CI95=1,1;DP4=0,0,8,6;MQ=37;FQ=-69	GT:PL:GQ	1/1:176,42,0:81
-19	7743284	.	A	G	102	.	DP=7;AF1=1;CI95=1,1;DP4=0,0,4,3;MQ=37;FQ=-48	GT:PL:GQ	1/1:135,21,0:39
-19	8034536	.	A	G	42.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:74,6,0:10
-19	8050872	.	T	G	87.1	.	DP=7;AF1=1;CI95=1,1;DP4=0,0,2,5;MQ=25;FQ=-48	GT:PL:GQ	1/1:120,21,0:39
-19	8050884	.	T	C	104	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,2,6;MQ=25;FQ=-51	GT:PL:GQ	1/1:137,24,0:45
-19	8050914	.	A	G	70	.	DP=11;AF1=1;CI95=1,1;DP4=0,0,2,9;MQ=29;FQ=-60	GT:PL:GQ	1/1:103,33,0:63
-19	8050917	.	G	A	103	.	DP=12;AF1=1;CI95=1,1;DP4=0,0,2,9;MQ=29;FQ=-60	GT:PL:GQ	1/1:136,33,0:63
-19	8050932	.	A	G	110	.	DP=13;AF1=1;CI95=1,1;DP4=0,0,3,10;MQ=30;FQ=-66	GT:PL:GQ	1/1:143,39,0:75
-19	8050976	.	G	T	182	.	DP=19;AF1=1;CI95=1,1;DP4=0,0,4,15;MQ=36;FQ=-84	GT:PL:GQ	1/1:215,57,0:99
-19	8050985	.	T	TA	214	.	INDEL;DP=20;AF1=1;CI95=1,1;DP4=0,0,4,16;MQ=37;FQ=-94.5	GT:PL:GQ	1/1:255,60,0:99
-19	8050996	.	T	C	169	.	DP=19;AF1=1;CI95=1,1;DP4=0,0,4,15;MQ=36;FQ=-84	GT:PL:GQ	1/1:202,57,0:99
-19	8051050	.	G	A	103	.	DP=19;AF1=1;CI95=1,1;DP4=0,0,6,12;MQ=35;FQ=-81	GT:PL:GQ	1/1:136,54,0:99
-19	8051066	.	G	A	122	.	DP=10;AF1=1;CI95=1,1;DP4=0,0,3,7;MQ=34;FQ=-57	GT:PL:GQ	1/1:155,30,0:57
-19	8051084	.	T	C	46.5	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,3,1;MQ=28;FQ=-39	GT:PL:GQ	1/1:79,12,0:21
-19	8051096	.	A	G	19	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=30;FQ=-36	GT:PL:GQ	1/1:51,9,0:15
-19	8051106	.	T	G	13	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=25;FQ=-33	GT:PL:GQ	1/1:44,6,0:9
-19	8051236	.	G	A	93.1	.	DP=7;AF1=1;CI95=1,1;DP4=0,0,4,3;MQ=27;FQ=-48	GT:PL:GQ	1/1:126,21,0:39
-19	8051264	.	G	A	52.1	.	DP=7;AF1=1;CI95=0.5,1;DP4=0,0,4,2;MQ=25;FQ=-45	GT:PL:GQ	1/1:85,18,0:33
-19	8051283	.	T	A	87.1	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,4,2;MQ=25;FQ=-45	GT:PL:GQ	1/1:120,18,0:33
-19	8051315	.	A	G	80.1	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,4,2;MQ=25;FQ=-45	GT:PL:GQ	1/1:113,18,0:33
-19	8051323	.	C	G	28	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=25;FQ=-36	GT:PL:GQ	1/1:60,9,0:16
-19	8051467	.	G	A	13	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=25;FQ=-33	GT:PL:GQ	1/1:44,6,0:9
-19	8051469	.	C	T	9.31	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=25;FQ=-33	GT:PL:GQ	1/1:40,6,0:8
-19	8051498	.	T	A	147	.	DP=11;AF1=1;CI95=1,1;DP4=0,0,4,7;MQ=26;FQ=-60	GT:PL:GQ	1/1:180,33,0:63
-19	8051502	.	C	T	113	.	DP=12;AF1=1;CI95=1,1;DP4=0,0,4,5;MQ=25;FQ=-54	GT:PL:GQ	1/1:146,27,0:51
-19	8051544	.	G	A	112	.	DP=14;AF1=1;CI95=1,1;DP4=0,0,3,10;MQ=29;FQ=-66	GT:PL:GQ	1/1:145,39,0:75
-19	8051546	.	T	C	104	.	DP=13;AF1=1;CI95=1,1;DP4=0,0,3,10;MQ=29;FQ=-66	GT:PL:GQ	1/1:137,39,0:75
-19	8051574	.	T	C	192	.	DP=13;AF1=1;CI95=1,1;DP4=0,0,3,10;MQ=29;FQ=-66	GT:PL:GQ	1/1:225,39,0:75
-19	8051593	.	T	C	45.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,0,5;MQ=35;FQ=-42	GT:PL:GQ	1/1:78,15,0:27
-19	8100673	.	C	G	3.54	.	DP=2;AF1=0.5001;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=3.25;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,30:29
-19	8326732	.	GA	G	45	.	INDEL;DP=4;AF1=1;CI95=0.5,1;DP4=0,0,0,4;MQ=32;FQ=-46.5	GT:PL:GQ	1/1:85,12,0:21
-19	8326738	.	T	A	12.3	.	DP=10;AF1=0.5012;CI95=0.5,0.5;DP4=1,0,0,3;MQ=32;FQ=-5.48;PV4=0.25,0.09,0.21,1	GT:PL:GQ	0/1:42,0,23:26
-19	8326742	.	A	C	77.1	.	DP=16;AF1=1;CI95=0.5,1;DP4=0,0,2,4;MQ=32;FQ=-45	GT:PL:GQ	1/1:110,18,0:33
-19	8347286	.	A	G	25	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=30;FQ=-36	GT:PL:GQ	1/1:57,9,0:15
-19	8347289	.	A	C	41.5	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,2,2;MQ=32;FQ=-39	GT:PL:GQ	1/1:74,12,0:21
-19	8347296	.	T	C	118	.	DP=7;AF1=1;CI95=0.5,1;DP4=0,0,4,2;MQ=33;FQ=-45	GT:PL:GQ	1/1:151,18,0:33
-19	8347384	.	G	GA	214	.	INDEL;DP=29;AF1=1;CI95=1,1;DP4=0,0,23,6;MQ=37;FQ=-122	GT:PL:GQ	1/1:255,87,0:99
-19	8347394	.	T	A	222	.	DP=28;AF1=1;CI95=1,1;DP4=0,0,22,5;MQ=37;FQ=-108	GT:PL:GQ	1/1:255,81,0:99
-19	8347399	.	C	G	167	.	DP=27;AF1=1;CI95=1,1;DP4=0,0,20,5;MQ=37;FQ=-102	GT:PL:GQ	1/1:200,75,0:99
-19	8347408	.	C	G	222	.	DP=23;AF1=1;CI95=1,1;DP4=0,0,17,5;MQ=37;FQ=-93	GT:PL:GQ	1/1:255,66,0:99
-19	8347594	.	A	G	78.1	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,3,3;MQ=25;FQ=-45	GT:PL:GQ	1/1:111,18,0:33
-19	8347628	.	A	G	108	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,5,3;MQ=28;FQ=-51	GT:PL:GQ	1/1:141,24,0:45
-19	8347638	.	G	T	99	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,5,3;MQ=28;FQ=-51	GT:PL:GQ	1/1:132,24,0:45
-19	8347649	.	T	C	107	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,5,3;MQ=28;FQ=-51	GT:PL:GQ	1/1:140,24,0:45
-19	8347659	.	T	C	106	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,5,3;MQ=28;FQ=-51	GT:PL:GQ	1/1:139,24,0:45
-19	8347769	.	T	G	26	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,1,2;MQ=25;FQ=-36	GT:PL:GQ	1/1:58,9,0:16
-19	8347801	.	A	G	150	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,4,4;MQ=30;FQ=-51	GT:PL:GQ	1/1:183,24,0:45
-19	8347804	.	A	G	106	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,4,4;MQ=30;FQ=-51	GT:PL:GQ	1/1:139,24,0:45
-19	8347809	.	T	C	79	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,4,4;MQ=30;FQ=-51	GT:PL:GQ	1/1:112,24,0:45
-19	8347870	.	T	C	149	.	DP=9;AF1=1;CI95=1,1;DP4=0,0,4,4;MQ=30;FQ=-51	GT:PL:GQ	1/1:182,24,0:45
-19	8347993	.	A	C	78	.	DP=13;AF1=1;CI95=1,1;DP4=0,0,0,10;MQ=25;FQ=-57	GT:PL:GQ	1/1:111,30,0:57
-19	8348001	.	T	G	86	.	DP=18;AF1=1;CI95=1,1;DP4=0,0,0,16;MQ=27;FQ=-75	GT:PL:GQ	1/1:119,48,0:93
-19	8348026	.	G	A	121	.	DP=26;AF1=1;CI95=1,1;DP4=0,0,2,24;MQ=31;FQ=-105	GT:PL:GQ	1/1:154,78,0:99
-19	8348048	.	A	G	222	.	DP=41;AF1=1;CI95=1,1;DP4=0,0,9,30;MQ=34;FQ=-144	GT:PL:GQ	1/1:255,117,0:99
-19	8348080	.	C	T	167	.	DP=46;AF1=1;CI95=1,1;DP4=0,0,20,26;MQ=35;FQ=-165	GT:PL:GQ	1/1:200,138,0:99
-19	8348129	.	G	A	222	.	DP=36;AF1=1;CI95=1,1;DP4=0,0,21,14;MQ=35;FQ=-132	GT:PL:GQ	1/1:255,105,0:99
-19	8348158	.	C	A	138	.	DP=18;AF1=1;CI95=1,1;DP4=0,0,12,3;MQ=32;FQ=-72	GT:PL:GQ	1/1:171,45,0:87
-19	8348160	.	T	A	179	.	DP=15;AF1=1;CI95=1,1;DP4=0,0,11,3;MQ=32;FQ=-69	GT:PL:GQ	1/1:212,42,0:81
-19	8348441	.	T	A	62.3	.	DP=8;AF1=1;CI95=0.5,1;DP4=0,0,2,3;MQ=25;FQ=-42	GT:PL:GQ	1/1:95,15,0:27
-19	8348471	.	C	T	222	.	DP=32;AF1=1;CI95=1,1;DP4=0,0,16,16;MQ=33;FQ=-123	GT:PL:GQ	1/1:255,96,0:99
-19	8348485	.	G	A	102	.	DP=40;AF1=1;CI95=1,1;DP4=0,0,21,18;MQ=34;FQ=-144	GT:PL:GQ	1/1:135,117,0:99
-19	8348498	.	G	A	217	.	DP=52;AF1=1;CI95=1,1;DP4=0,0,29,22;MQ=35;FQ=-181	GT:PL:GQ	1/1:250,154,0:99
-19	8348514	.	T	C	212	.	DP=59;AF1=1;CI95=1,1;DP4=0,0,35,24;MQ=35;FQ=-205	GT:PL:GQ	1/1:245,178,0:99
-19	8348590	.	A	G	172	.	DP=20;AF1=1;CI95=1,1;DP4=0,0,14,5;MQ=36;FQ=-84	GT:PL:GQ	1/1:205,57,0:99
-19	8348635	.	T	C	146	.	DP=12;AF1=1;CI95=1,1;DP4=0,0,2,9;MQ=37;FQ=-60	GT:PL:GQ	1/1:179,33,0:63
-19	8348642	.	T	C	222	.	DP=16;AF1=1;CI95=1,1;DP4=0,0,3,13;MQ=37;FQ=-75	GT:PL:GQ	1/1:255,48,0:93
-19	8348695	.	T	TA	214	.	INDEL;DP=18;AF1=1;CI95=1,1;DP4=0,0,4,13;MQ=37;FQ=-85.5	GT:PL:GQ	1/1:255,51,0:99
-19	8348701	.	C	T	155	.	DP=18;AF1=1;CI95=1,1;DP4=0,0,4,14;MQ=37;FQ=-81	GT:PL:GQ	1/1:188,54,0:99
-19	8348922	.	T	C	222	.	DP=13;AF1=1;CI95=1,1;DP4=0,0,7,5;MQ=37;FQ=-63	GT:PL:GQ	1/1:255,36,0:69
-19	8348969	.	T	C	161	.	DP=15;AF1=1;CI95=1,1;DP4=0,0,8,7;MQ=37;FQ=-72	GT:PL:GQ	1/1:194,45,0:87
-19	8349035	.	G	A	50.1	.	DP=7;AF1=1;CI95=0.5,1;DP4=0,0,5,1;MQ=33;FQ=-45	GT:PL:GQ	1/1:83,18,0:33
-19	8349037	.	G	A	56.1	.	DP=7;AF1=1;CI95=0.5,1;DP4=0,0,5,1;MQ=33;FQ=-45	GT:PL:GQ	1/1:89,18,0:33
-19	8349080	.	A	G	33.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,5,0;MQ=33;FQ=-42	GT:PL:GQ	1/1:66,15,0:27
-19	8349101	.	C	G	83.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,5,0;MQ=33;FQ=-42	GT:PL:GQ	1/1:116,15,0:27
-19	8549054	.	T	G	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	8553877	.	G	C	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	8555072	.	A	C	4.13	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:32,3,0:3
-19	8741092	.	G	T	5.46	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:34,3,0:3
-19	8783635	.	C	CA	147	.	INDEL;DP=23;AF1=0.5;CI95=0.5,0.5;DP4=2,6,10,2;MQ=36;FQ=126;PV4=0.019,1,0.12,0.01	GT:PL:GQ	0/1:185,0,161:99
-19	8783903	.	G	GTC	21.3	.	INDEL;DP=4;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:60,6,0:10
-19	8812489	.	GT	G	34.5	.	INDEL;DP=5;AF1=0.5;CI95=0.5,0.5;DP4=0,2,2,1;MQ=35;FQ=18.5;PV4=0.4,0.047,0.25,0.0021	GT:PL:GQ	0/1:72,0,53:56
-19	8817010	.	C	T	3.01	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,1,0;MQ=37;FQ=3.01;PV4=1,1,1,1	GT:PL:GQ	0/1:30,0,30:28
-19	8838292	.	G	A	23	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,0,3;MQ=37;FQ=-36	GT:PL:GQ	1/1:55,9,0:15
-19	8838395	.	C	A	3.55	.	DP=2;AF1=0.5014;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=-6.58;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,22:26
-19	8841856	.	G	GCA	36.5	.	INDEL;DP=8;AF1=0.5;CI95=0.5,0.5;DP4=2,1,0,4;MQ=36;FQ=38.3;PV4=0.14,0.19,0.22,0.058	GT:PL:GQ	0/1:74,0,79:76
-19	8850152	.	G	C	5.46	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:34,3,0:3
-19	8895305	.	T	A	7.8	.	DP=20;AF1=0.5;CI95=0.5,0.5;DP4=3,5,3,1;MQ=37;FQ=10.4;PV4=0.55,0.0027,1,1.9e-09	GT:PL:GQ	0/1:37,0,157:39
-19	8899002	.	T	G	16.1	.	DP=39;AF1=0.5;CI95=0.5,0.5;DP4=2,3,7,0;MQ=36;FQ=19.1;PV4=0.045,0.00068,1,1	GT:PL:GQ	0/1:46,0,85:49
-19	8900459	.	C	G	7.8	.	DP=6;AF1=0.5;CI95=0.5,0.5;DP4=1,1,0,3;MQ=37;FQ=10.4;PV4=0.4,0.0097,1,0.0075	GT:PL:GQ	0/1:37,0,59:39
-19	8900460	.	AG	AGG	24.5	.	INDEL;DP=6;AF1=0.5;CI95=0.5,0.5;DP4=1,1,1,1;MQ=37;FQ=21.3;PV4=1,1,1,0.012	GT:PL:GQ	0/1:62,0,57:59
-19	8900589	.	AGG	AG	16.6	.	INDEL;DP=5;AF1=0.5;CI95=0.5,0.5;DP4=0,2,0,2;MQ=37;FQ=17.4;PV4=1,0.31,1,0.03	GT:PL:GQ	0/1:54,0,56:55
-19	8901128	.	T	TG	15.6	.	INDEL;DP=6;AF1=0.5;CI95=0.5,0.5;DP4=0,2,0,3;MQ=37;FQ=6.39;PV4=1,0.37,1,0.00012	GT:PL:GQ	0/1:53,0,40:43
-19	8904439	.	TGG	TG	75.5	.	INDEL;DP=15;AF1=0.5;CI95=0.5,0.5;DP4=2,1,3,3;MQ=35;FQ=43.5;PV4=1,0.004,0.16,0.034	GT:PL:GQ	0/1:113,0,78:81
-19	8904440	.	G	GT	66.5	.	INDEL;DP=13;AF1=0.5;CI95=0.5,0.5;DP4=2,1,4,2;MQ=35;FQ=43.5;PV4=1,0.044,0.16,0.036	GT:PL:GQ	0/1:104,0,78:81
-19	8905828	.	T	A	4.77	.	DP=7;AF1=0.4999;CI95=0.5,0.5;DP4=2,0,3,0;MQ=37;FQ=6.95;PV4=1,0.007,1,0.11	GT:PL:GQ	0/1:33,0,53:33
-19	8920813	.	CGG	CG	10.8	.	INDEL;DP=6;AF1=0.5;CI95=0.5,0.5;DP4=0,2,0,2;MQ=37;FQ=13.1;PV4=1,0.0022,1,0.012	GT:PL:GQ	0/1:48,0,56:50
-19	8927995	.	C	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	8948001	.	C	G	23	.	DP=9;AF1=0.5;CI95=0.5,0.5;DP4=0,2,1,2;MQ=37;FQ=22.5;PV4=1,0.0043,1,0.27	GT:PL:GQ	0/1:53,0,52:52
-19	8966507	.	A	G	5.46	.	DP=6;AF1=0.4999;CI95=0.5,0.5;DP4=1,3,2,0;MQ=37;FQ=7.8;PV4=0.4,0.16,1,0.22	GT:PL:GQ	0/1:34,0,99:34
-19	8977007	.	GA	G	22.2	.	INDEL;DP=5;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:61,6,0:10
-19	8977011	.	G	A	79.1	.	DP=10;AF1=1;CI95=1,1;DP4=0,0,2,5;MQ=37;FQ=-48	GT:PL:GQ	1/1:112,21,0:39
-19	8979553	.	G	GC	41.5	.	INDEL;DP=4;AF1=0.501;CI95=0.5,0.5;DP4=0,1,3,0;MQ=37;FQ=-10.9;PV4=0.25,1,1,1	GT:PL:GQ	0/1:79,0,24:27
-19	8981699	.	C	CA	22.2	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:61,6,0:10
-19	8989644	.	A	C	3.41	.	DP=11;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-33	GT:PL:GQ	1/1:32,6,0:4
-19	8989891	.	C	T	8.65	.	DP=5;AF1=0.5005;CI95=0.5,0.5;DP4=0,1,1,1;MQ=37;FQ=-3.17;PV4=1,0.18,1,0.16	GT:PL:GQ	0/1:38,0,27:31
-19	8990112	.	C	A	7.59	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:38,6,0:7
-19	8999131	.	A	G	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	9010575	.	T	G	3.56	.	DP=2;AF1=0.503;CI95=0.5,0.5;DP4=1,0,1,0;MQ=32;FQ=-8.86;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,19:25
-19	9010791	.	C	A	7.8	.	DP=6;AF1=0.5;CI95=0.5,0.5;DP4=1,2,0,3;MQ=37;FQ=10.4;PV4=1,0.0042,1,0.093	GT:PL:GQ	0/1:37,0,84:39
-19	9020243	.	TA	T	18.5	.	INDEL;DP=8;AF1=0.5;CI95=0.5,0.5;DP4=0,4,1,2;MQ=36;FQ=21.5;PV4=0.43,0.00079,0.14,0.18	GT:PL:GQ	0/1:56,0,93:59
-19	9066341	.	G	T	3.01	.	DP=2;AF1=0.4999;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=3.25;PV4=1,1,1,1	GT:PL:GQ	0/1:30,0,31:28
-19	9096827	.	A	G	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-19	9097851	.	C	A	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	9100285	.	G	T	3.59	.	DP=2;AF1=0.51;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=-13.3;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,14:21
-19	9126825	.	A	T	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-19	9148172	.	T	C	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-19	9216844	.	T	A	4.13	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:32,3,0:3
-19	9358012	.	G	A	164	.	DP=11;AF1=1;CI95=1,1;DP4=0,0,10,1;MQ=37;FQ=-60	GT:PL:GQ	1/1:197,33,0:63
-19	9358045	.	C	A	191	.	DP=22;AF1=1;CI95=1,1;DP4=0,0,15,6;MQ=37;FQ=-90	GT:PL:GQ	1/1:224,63,0:99
-19	9358292	.	A	G	167	.	DP=58;AF1=1;CI95=1,1;DP4=0,0,27,24;MQ=37;FQ=-181	GT:PL:GQ	1/1:200,154,0:99
-19	9358454	.	G	A	222	.	DP=78;AF1=1;CI95=1,1;DP4=0,0,42,36;MQ=37;FQ=-262	GT:PL:GQ	1/1:255,235,0:99
-19	9358486	.	T	G	158	.	DP=62;AF1=1;CI95=1,1;DP4=0,0,25,32;MQ=37;FQ=-199	GT:PL:GQ	1/1:191,172,0:99
-19	9358567	.	A	G	222	.	DP=50;AF1=1;CI95=1,1;DP4=0,0,11,39;MQ=37;FQ=-178	GT:PL:GQ	1/1:255,151,0:99
-19	9632540	.	A	G	222	.	DP=19;AF1=1;CI95=1,1;DP4=0,0,11,7;MQ=37;FQ=-81	GT:PL:GQ	1/1:255,54,0:99
-19	9632576	.	A	G	222	.	DP=27;AF1=1;CI95=1,1;DP4=0,0,16,10;MQ=37;FQ=-105	GT:PL:GQ	1/1:255,78,0:99
-19	9632798	.	A	G	140	.	DP=29;AF1=1;CI95=1,1;DP4=0,0,14,14;MQ=37;FQ=-111	GT:PL:GQ	1/1:173,84,0:99
-19	9633610	.	T	C	30.8	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=32;FQ=-33	GT:PL:GQ	1/1:62,6,0:10
-19	9633663	.	T	G	40	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=30;FQ=-36	GT:PL:GQ	1/1:72,9,0:16
-19	9633666	.	A	G	39	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=30;FQ=-36	GT:PL:GQ	1/1:71,9,0:16
-19	9681721	.	G	A	148	.	DP=11;AF1=0.5;CI95=0.5,0.5;DP4=3,0,5,3;MQ=35;FQ=36;PV4=0.49,0.19,0.19,1	GT:PL:GQ	0/1:178,0,63:66
-19	9681741	.	A	T	81	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,6,2;MQ=34;FQ=-51	GT:PL:GQ	1/1:114,24,0:45
-19	9681750	.	T	A	61.1	.	DP=7;AF1=1;CI95=1,1;DP4=0,0,6,1;MQ=34;FQ=-48	GT:PL:GQ	1/1:94,21,0:39
-19	9681756	.	G	A	45.3	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,5,0;MQ=33;FQ=-42	GT:PL:GQ	1/1:78,15,0:27
-19	9681764	.	A	T	39.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,4,0;MQ=32;FQ=-39	GT:PL:GQ	1/1:72,12,0:21
-19	9684345	.	A	G	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-19	9952338	.	C	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	10057473	.	G	GTC	75.5	.	INDEL;DP=29;AF1=0.5;CI95=0.5,0.5;DP4=1,4,10,0;MQ=33;FQ=73;PV4=0.0037,0.17,0.012,1	GT:PL:GQ	0/1:113,0,109:99
-19	10059270	.	G	C	21	.	DP=35;AF1=0.5;CI95=0.5,0.5;DP4=4,11,0,9;MQ=36;FQ=24;PV4=0.26,3e-14,0.0078,3.5e-05	GT:PL:GQ	0/1:51,0,255:54
-19	10060151	.	CAAA	CAA	27.2	.	INDEL;DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:66,6,0:10
-19	10126690	.	A	AC	14.6	.	INDEL;DP=4;AF1=0.5;CI95=0.5,0.5;DP4=0,2,2,0;MQ=37;FQ=16.1;PV4=0.33,1,1,0.0011	GT:PL:GQ	0/1:52,0,56:53
-19	10130185	.	GT	G	33.4	.	INDEL;DP=5;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=30;FQ=-43.5	GT:PL:GQ	1/1:73,9,0:16
-19	10133086	.	A	G	170	.	DP=27;AF1=0.5;CI95=0.5,0.5;DP4=10,6,7,4;MQ=37;FQ=173;PV4=1,0.5,1,1	GT:PL:GQ	0/1:200,0,255:99
-19	10153682	.	A	C	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-19	10157183	.	G	T	35	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=37;FQ=-36	GT:PL:GQ	1/1:67,9,0:16
-19	10163595	.	A	AG	27.2	.	INDEL;DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:66,6,0:10
-19	10250372	.	G	A	32	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,0,3;MQ=33;FQ=-36	GT:PL:GQ	1/1:64,9,0:16
-19	10250380	.	A	G	72.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,1,4;MQ=35;FQ=-42	GT:PL:GQ	1/1:105,15,0:27
-19	10250405	.	A	G	159	.	DP=9;AF1=1;CI95=1,1;DP4=0,0,4,4;MQ=32;FQ=-51	GT:PL:GQ	1/1:192,24,0:45
-19	10250417	.	T	C	222	.	DP=13;AF1=1;CI95=1,1;DP4=0,0,9,4;MQ=33;FQ=-66	GT:PL:GQ	1/1:255,39,0:75
-19	10250483	.	A	T	110	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,8,0;MQ=32;FQ=-51	GT:PL:GQ	1/1:143,24,0:45
-19	10250497	.	C	G	55	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,8,0;MQ=32;FQ=-51	GT:PL:GQ	1/1:88,24,0:45
-19	10250501	.	C	T	74	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,8,0;MQ=32;FQ=-51	GT:PL:GQ	1/1:107,24,0:45
-19	10262515	.	A	T	3.58	.	DP=2;AF1=0.5078;CI95=0.5,0.5;DP4=0,1,1,0;MQ=37;FQ=-12.4;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,15:21
-19	10268290	.	T	TTC	56.5	.	INDEL;DP=5;AF1=0.5016;CI95=0.5,0.5;DP4=0,1,4,0;MQ=37;FQ=-12.8;PV4=0.2,0.49,1,0.13	GT:PL:GQ	0/1:94,0,22:25
-19	10281024	.	G	T	7.8	.	DP=5;AF1=0.5007;CI95=0.5,0.5;DP4=0,1,3,0;MQ=37;FQ=-4.28;PV4=0.25,0.023,1,0.14	GT:PL:GQ	0/1:37,0,25:29
-19	10297732	.	TGG	TGGGG	50.4	.	INDEL;DP=9;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=37;FQ=-43.5	GT:PL:GQ	1/1:90,9,0:16
-19	10498385	.	A	T	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	10502388	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	10525511	.	A	C	13.2	.	DP=9;AF1=0.5;CI95=0.5,0.5;DP4=4,1,0,4;MQ=33;FQ=16.1;PV4=0.048,0.019,0.0056,1	GT:PL:GQ	0/1:43,0,107:46
-19	10590412	.	G	C	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-19	10607212	.	A	G	4.13	.	DP=7;AF1=0.4998;CI95=0.5,0.5;DP4=1,2,2,0;MQ=37;FQ=6.2;PV4=0.4,0.00041,1,1	GT:PL:GQ	0/1:32,0,89:31
-19	10656785	.	TA	TAAA	37.4	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,0,3;MQ=37;FQ=-43.5	GT:PL:GQ	1/1:77,9,0:16
-19	10663128	.	A	G	121	.	DP=22;AF1=0.5;CI95=0.5,0.5;DP4=5,5,7,5;MQ=37;FQ=124;PV4=1,0.0086,1,1	GT:PL:GQ	0/1:151,0,173:99
-19	10669900	.	TC	TCC	21.5	.	INDEL;DP=3;AF1=0.5013;CI95=0.5,0.5;DP4=0,1,2,0;MQ=37;FQ=-11.8;PV4=0.33,1,1,0.027	GT:PL:GQ	0/1:59,0,23:26
-19	10681183	.	G	C	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	10689339	.	TA	TAAA	82.7	.	INDEL;DP=7;AF1=1;CI95=0.5,1;DP4=0,0,0,5;MQ=37;FQ=-49.5	GT:PL:GQ	1/1:123,15,0:27
-19	10690081	.	GT	GTTT	23.2	.	INDEL;DP=6;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:62,6,0:10
-19	10698013	.	G	C	4.61	.	DP=8;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:34,6,0:5
-19	10699336	.	AGG	AG	73.5	.	INDEL;DP=7;AF1=0.5016;CI95=0.5,0.5;DP4=1,0,2,2;MQ=37;FQ=-12.8;PV4=1,1,1,0.14	GT:PL:GQ	0/1:111,0,22:25
-19	10700484	.	A	C	122	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,4,2;MQ=37;FQ=-45	GT:PL:GQ	1/1:155,18,0:33
-19	10700486	.	G	GC	95	.	INDEL;DP=6;AF1=1;CI95=0.5,1;DP4=0,0,2,2;MQ=37;FQ=-46.5	GT:PL:GQ	1/1:135,12,0:21
-19	10701724	.	AGG	AG	19.5	.	INDEL;DP=12;AF1=0.5;CI95=0.5,0.5;DP4=1,4,2,1;MQ=37;FQ=22.5;PV4=0.46,0.32,1,0.0032	GT:PL:GQ	0/1:57,0,130:60
-19	10702354	.	T	TCTGG	73	.	INDEL;DP=10;AF1=1;CI95=0.5,1;DP4=0,0,4,0;MQ=37;FQ=-46.5	GT:PL:GQ	1/1:113,12,0:21
-19	10773851	.	G	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	10788446	.	T	C	13.2	.	DP=32;AF1=0.5;CI95=0.5,0.5;DP4=12,1,0,7;MQ=37;FQ=16.1;PV4=0.0001,0.00062,1,1	GT:PL:GQ	0/1:43,0,165:46
-19	10924486	.	T	C	3.55	.	DP=2;AF1=0.5006;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=-4.74;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,25:28
-19	10927766	.	G	GAT	11.8	.	INDEL;DP=5;AF1=0.5;CI95=0.5,0.5;DP4=0,3,1,1;MQ=37;FQ=14.6;PV4=0.4,0.22,1,0.0014	GT:PL:GQ	0/1:49,0,79:51
-19	10947182	.	G	C	41.8	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:73,6,0:10
-19	10948976	.	TC	TCC	64.9	.	INDEL;DP=7;AF1=0.5554;CI95=0.5,1;DP4=1,0,3,2;MQ=35;FQ=-27.5;PV4=1,0.27,1,0.35	GT:PL:GQ	0/1:102,0,7:10
-19	10972143	.	G	T	8.44	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:39,6,0:8
-19	10975413	.	C	CA	12.5	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:51,6,0:9
-19	11017779	.	TC	TCAC	16.3	.	INDEL;DP=4;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=32;FQ=-40.5	GT:PL:GQ	1/1:55,6,0:10
-19	11122585	.	T	TC	53.7	.	INDEL;DP=9;AF1=1;CI95=0.5,1;DP4=0,0,5,0;MQ=33;FQ=-49.5	GT:PL:GQ	1/1:94,15,0:27
-19	11165572	.	A	G	222	.	DP=16;AF1=1;CI95=1,1;DP4=0,0,10,6;MQ=37;FQ=-75	GT:PL:GQ	1/1:255,48,0:93
-19	11165677	.	G	A	49.1	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,3,3;MQ=37;FQ=-45	GT:PL:GQ	1/1:82,18,0:33
-19	11165689	.	T	A	85.1	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,3,3;MQ=37;FQ=-45	GT:PL:GQ	1/1:118,18,0:33
-19	11165712	.	A	G	57.3	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,3,2;MQ=37;FQ=-42	GT:PL:GQ	1/1:90,15,0:27
-19	11196378	.	CTTT	CTTTT	214	.	INDEL;DP=34;AF1=1;CI95=1,1;DP4=0,0,18,15;MQ=37;FQ=-134	GT:PL:GQ	1/1:255,99,0:99
-19	11196544	.	C	T	141	.	DP=19;AF1=1;CI95=1,1;DP4=0,0,7,11;MQ=37;FQ=-81	GT:PL:GQ	1/1:174,54,0:99
-19	11196769	.	A	G	174	.	DP=23;AF1=1;CI95=1,1;DP4=0,0,6,15;MQ=37;FQ=-90	GT:PL:GQ	1/1:207,63,0:99
-19	11402540	.	TC	T	32.4	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=37;FQ=-43.5	GT:PL:GQ	1/1:72,9,0:16
-19	11465876	.	C	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	11467556	.	ATGTGTGTGTGTGTGT	ATGTGTGTGTGTGT	216	.	INDEL;DP=92;AF1=0.5;CI95=0.5,0.5;DP4=19,27,6,22;MQ=37;FQ=217;PV4=0.13,0.00092,0.36,1	GT:PL:GQ	0/1:254,0,255:99
-19	11472871	.	G	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	11489280	.	A	T	13	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=32;FQ=-33	GT:PL:GQ	1/1:44,6,0:9
-19	11537444	.	C	CG	48.5	.	INDEL;DP=6;AF1=0.5016;CI95=0.5,0.5;DP4=1,0,0,4;MQ=37;FQ=-12.8;PV4=0.2,0.18,1,1	GT:PL:GQ	0/1:86,0,22:25
-19	11544046	.	G	GCT	74.5	.	INDEL;DP=28;AF1=1;CI95=1,1;DP4=0,0,9,0;MQ=35;FQ=-61.5	GT:PL:GQ	1/1:115,27,0:51
-19	11546250	.	A	G	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	11583902	.	A	C	3.54	.	DP=2;AF1=0.5001;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=-3.07;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,29:29
-19	11593164	.	G	GCC	121	.	INDEL;DP=16;AF1=1;CI95=0.5,1;DP4=1,0,15,0;MQ=36;FQ=-45.5;PV4=1,1,0.36,0.34	GT:PL:GQ	1/1:161,11,0:19
-19	11593167	.	A	G	32	.	DP=16;AF1=1;CI95=0.5,1;DP4=1,0,10,0;MQ=37;FQ=-30;PV4=1,0.0089,1,1	GT:PL:GQ	1/1:62,3,0:6
-19	11632363	.	A	AGT	45.4	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,0,3;MQ=37;FQ=-43.5	GT:PL:GQ	1/1:85,9,0:16
-19	11660704	.	GAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAG	GAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAG	8.83	.	INDEL;DP=6;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:47,6,0:8
-19	11661671	.	TC	TCC	29.2	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:68,6,0:10
-19	11676455	.	CT	C	14.6	.	INDEL;DP=9;AF1=0.5;CI95=0.5,0.5;DP4=0,2,1,1;MQ=37;FQ=14.1;PV4=1,0.25,1,0.23	GT:PL:GQ	0/1:52,0,51:51
-19	11677634	.	A	G	15.1	.	DP=8;AF1=1;CI95=0.5,1;DP4=0,0,0,3;MQ=30;FQ=-36	GT:PL:GQ	1/1:47,9,0:14
-19	11777860	.	A	G	49.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,2,2;MQ=25;FQ=-39	GT:PL:GQ	1/1:82,12,0:21
-19	11777864	.	C	G	51.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,2,2;MQ=25;FQ=-39	GT:PL:GQ	1/1:84,12,0:21
-19	11777878	.	C	G	58.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,2,2;MQ=25;FQ=-39	GT:PL:GQ	1/1:91,12,0:21
-19	11777923	.	T	C	47.5	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,3,1;MQ=28;FQ=-39	GT:PL:GQ	1/1:80,12,0:21
-19	11777948	.	C	G	43.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,3,1;MQ=28;FQ=-39	GT:PL:GQ	1/1:76,12,0:21
-19	11839957	.	A	G	38.1	.	DP=10;AF1=0.5064;CI95=0.5,0.5;DP4=0,1,4,2;MQ=34;FQ=-11.3;PV4=0.43,0.0041,0.29,0.17	GT:PL:GQ	0/1:68,0,16:19
-19	11839959	.	A	G	32.1	.	DP=11;AF1=0.508;CI95=0.5,0.5;DP4=0,1,4,2;MQ=34;FQ=-12.3;PV4=0.43,0.0011,0.29,0.17	GT:PL:GQ	0/1:62,0,15:18
-19	11839992	.	A	G	106	.	DP=18;AF1=1;CI95=0.5,1;DP4=0,1,13,3;MQ=35;FQ=-41;PV4=0.24,3.8e-07,0.33,0.34	GT:PL:GQ	1/1:139,14,0:25
-19	11840001	.	T	C	112	.	DP=20;AF1=1;CI95=1,1;DP4=0,1,15,3;MQ=35;FQ=-47;PV4=0.21,7.2e-06,0.34,0.37	GT:PL:GQ	1/1:145,20,0:37
-19	11840069	.	T	C	86.1	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,5,1;MQ=37;FQ=-45	GT:PL:GQ	1/1:119,18,0:33
-19	11840074	.	GATCATCA	GATCA	60.4	.	INDEL;DP=5;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=37;FQ=-43.5	GT:PL:GQ	1/1:100,9,0:16
-19	11840087	.	A	G	19.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:51,6,0:10
-19	11840209	.	A	G	76.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,2,3;MQ=25;FQ=-42	GT:PL:GQ	1/1:109,15,0:27
-19	11840219	.	C	G	66.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,2,3;MQ=25;FQ=-42	GT:PL:GQ	1/1:99,15,0:27
-19	11840229	.	T	G	65.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,2,3;MQ=25;FQ=-42	GT:PL:GQ	1/1:98,15,0:27
-19	11840237	.	A	T	42.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,2,3;MQ=25;FQ=-42	GT:PL:GQ	1/1:75,15,0:27
-19	11840260	.	G	C	35.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,2,2;MQ=25;FQ=-39	GT:PL:GQ	1/1:68,12,0:21
-19	11904739	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	11952270	.	A	G	222	.	DP=34;AF1=1;CI95=1,1;DP4=0,1,13,20;MQ=35;FQ=-92;PV4=1,0.16,0.29,1	GT:PL:GQ	1/1:255,65,0:99
-19	11952283	.	T	C	165	.	DP=38;AF1=1;CI95=1,1;DP4=0,0,14,21;MQ=35;FQ=-132	GT:PL:GQ	1/1:198,105,0:99
-19	11952293	.	A	G	222	.	DP=45;AF1=1;CI95=1,1;DP4=0,0,19,25;MQ=34;FQ=-159	GT:PL:GQ	1/1:255,132,0:99
-19	11952355	.	G	C	21.3	.	DP=14;AF1=1;CI95=0.5,1;DP4=0,0,5,0;MQ=30;FQ=-42	GT:PL:GQ	1/1:54,15,0:26
-19	11952357	.	T	C	39.1	.	DP=14;AF1=1;CI95=0.5,1;DP4=0,0,5,1;MQ=32;FQ=-45	GT:PL:GQ	1/1:72,18,0:33
-19	11952381	.	C	T	82.1	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,5,2;MQ=36;FQ=-48	GT:PL:GQ	1/1:115,21,0:39
-19	11952422	.	CTC	CTCGTC	88.7	.	INDEL;DP=5;AF1=1;CI95=0.5,1;DP4=0,0,0,5;MQ=37;FQ=-49.5	GT:PL:GQ	1/1:129,15,0:27
-19	11952453	.	T	C	88.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,0,5;MQ=37;FQ=-42	GT:PL:GQ	1/1:121,15,0:27
-19	11952566	.	C	G	112	.	DP=9;AF1=1;CI95=1,1;DP4=0,0,5,4;MQ=37;FQ=-54	GT:PL:GQ	1/1:145,27,0:51
-19	11952602	.	C	T	186	.	DP=21;AF1=1;CI95=1,1;DP4=0,0,12,9;MQ=37;FQ=-90	GT:PL:GQ	1/1:219,63,0:99
-19	11952628	.	CTCTTCT	CTCT	15.6	.	INDEL;DP=28;AF1=0.5;CI95=0.5,0.5;DP4=10,13,3,1;MQ=37;FQ=18.5;PV4=0.33,1,1,1	GT:PL:GQ	0/1:53,0,255:56
-19	11952659	.	A	C	172	.	DP=21;AF1=1;CI95=1,1;DP4=0,0,9,12;MQ=37;FQ=-90	GT:PL:GQ	1/1:205,63,0:99
-19	11952675	.	T	C	178	.	DP=17;AF1=1;CI95=1,1;DP4=0,0,8,8;MQ=37;FQ=-75	GT:PL:GQ	1/1:211,48,0:93
-19	11952711	.	TA	T	31.5	.	INDEL;DP=11;AF1=0.5;CI95=0.5,0.5;DP4=0,4,1,2;MQ=37;FQ=34.4;PV4=0.43,1,1,0.0096	GT:PL:GQ	0/1:69,0,86:72
-19	11952712	.	AGCTGCTGCTGCTGC	AGCTGCTGCTGCTGCTGC	99.6	.	INDEL;DP=9;AF1=1;CI95=0.5,1;DP4=0,0,0,6;MQ=37;FQ=-52.5	GT:PL:GQ	1/1:140,18,0:33
-19	11952805	.	A	G	198	.	DP=21;AF1=1;CI95=1,1;DP4=0,0,8,12;MQ=37;FQ=-87	GT:PL:GQ	1/1:231,60,0:99
-19	11952841	.	T	G	191	.	DP=24;AF1=1;CI95=1,1;DP4=0,0,16,7;MQ=36;FQ=-96	GT:PL:GQ	1/1:224,69,0:99
-19	11952882	.	A	C	140	.	DP=28;AF1=1;CI95=1,1;DP4=0,0,22,6;MQ=34;FQ=-111	GT:PL:GQ	1/1:173,84,0:99
-19	11952895	.	A	G	104	.	DP=25;AF1=1;CI95=1,1;DP4=0,0,21,1;MQ=34;FQ=-93	GT:PL:GQ	1/1:137,66,0:99
-19	11997967	.	G	C	6.98	.	DP=3;AF1=0.5003;CI95=0.5,0.5;DP4=1,0,2,0;MQ=33;FQ=3.2;PV4=1,0.019,0.33,1	GT:PL:GQ	0/1:36,0,28:31
-19	12033202	.	G	A	27	.	DP=4;AF1=0.5008;CI95=0.5,0.5;DP4=0,1,1,2;MQ=28;FQ=-4.12;PV4=1,0.048,0,0.22	GT:PL:GQ	0/1:57,0,25:28
-19	12033225	.	T	G	178	.	DP=15;AF1=1;CI95=0.5,1;DP4=0,1,5,7;MQ=34;FQ=-29;PV4=1,0.23,0.26,0.1	GT:PL:GQ	1/1:207,2,0:5
-19	12033238	.	T	C	222	.	DP=23;AF1=1;CI95=1,1;DP4=0,1,10,9;MQ=35;FQ=-50;PV4=1,0.39,0.32,0.24	GT:PL:GQ	1/1:255,23,0:43
-19	12033263	.	A	G	222	.	DP=32;AF1=1;CI95=1,1;DP4=0,0,15,15;MQ=36;FQ=-117	GT:PL:GQ	1/1:255,90,0:99
-19	12033304	.	A	G	222	.	DP=41;AF1=1;CI95=1,1;DP4=0,0,18,23;MQ=36;FQ=-150	GT:PL:GQ	1/1:255,123,0:99
-19	12033367	.	A	C	152	.	DP=32;AF1=1;CI95=1,1;DP4=0,0,11,19;MQ=37;FQ=-117	GT:PL:GQ	1/1:185,90,0:99
-19	12033372	.	TC	TCC	214	.	INDEL;DP=30;AF1=1;CI95=1,1;DP4=0,0,11,18;MQ=37;FQ=-122	GT:PL:GQ	1/1:255,87,0:99
-19	12033396	.	T	C	192	.	DP=21;AF1=1;CI95=1,1;DP4=0,0,9,11;MQ=37;FQ=-87	GT:PL:GQ	1/1:225,60,0:99
-19	12033437	.	A	G	181	.	DP=8;AF1=1;CI95=1,1;DP4=0,0,4,4;MQ=37;FQ=-51	GT:PL:GQ	1/1:214,24,0:45
-19	12052486	.	T	C	3.55	.	DP=2;AF1=0.5011;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=-5.91;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,23:27
-19	12063068	.	G	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	12075788	.	A	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	12596319	.	G	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	12761248	.	C	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	12761275	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	12845038	.	AT	ATT	11.5	.	INDEL;DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:50,6,0:9
-19	12873388	.	C	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	12979639	.	A	T	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-19	12979730	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	12979796	.	G	A	25.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=32;FQ=-33	GT:PL:GQ	1/1:57,6,0:10
-19	12980273	.	G	A	29	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,1,2;MQ=37;FQ=-36	GT:PL:GQ	1/1:61,9,0:16
-19	12980707	.	A	G	86	.	DP=10;AF1=1;CI95=1,1;DP4=0,0,3,6;MQ=37;FQ=-54	GT:PL:GQ	1/1:119,27,0:51
-19	12980733	.	G	A	124	.	DP=13;AF1=1;CI95=1,1;DP4=0,0,4,9;MQ=37;FQ=-66	GT:PL:GQ	1/1:157,39,0:75
-19	12980760	.	C	G	222	.	DP=15;AF1=1;CI95=1,1;DP4=0,0,3,12;MQ=37;FQ=-72	GT:PL:GQ	1/1:255,45,0:87
-19	12980967	.	G	A	104	.	DP=10;AF1=1;CI95=1,1;DP4=0,0,3,6;MQ=37;FQ=-54	GT:PL:GQ	1/1:137,27,0:51
-19	12981016	.	T	C	222	.	DP=15;AF1=1;CI95=1,1;DP4=0,0,9,6;MQ=37;FQ=-72	GT:PL:GQ	1/1:255,45,0:87
-19	13670070	.	C	T	13.9	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=25;FQ=-33	GT:PL:GQ	1/1:45,6,0:10
-19	13670140	.	C	T	28	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=25;FQ=-36	GT:PL:GQ	1/1:60,9,0:16
-19	13670153	.	A	G	30	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=25;FQ=-36	GT:PL:GQ	1/1:62,9,0:16
-19	13670161	.	G	A	27	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=25;FQ=-36	GT:PL:GQ	1/1:59,9,0:16
-19	14007582	.	C	A	3.98	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-33	GT:PL:GQ	1/1:33,6,0:5
-19	14007612	.	AAGAGAG	AAGAG	28.2	.	INDEL;DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:67,6,0:10
-19	14070075	.	T	A	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	14524333	.	TAG	T	14.6	.	INDEL;DP=4;AF1=0.5004;CI95=0.5,0.5;DP4=1,0,1,1;MQ=37;FQ=-7.41;PV4=1,1,1,0.39	GT:PL:GQ	0/1:52,0,28:31
-19	14527043	.	T	A	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	14580308	.	T	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	14592466	.	GC	GCCC	22.2	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:61,6,0:10
-19	14607703	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	15533970	.	T	C	51	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,1,2;MQ=30;FQ=-36	GT:PL:GQ	1/1:83,9,0:16
-19	15533994	.	A	G	45.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,3;MQ=32;FQ=-39	GT:PL:GQ	1/1:78,12,0:21
-19	15534018	.	A	G	42.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,3;MQ=32;FQ=-39	GT:PL:GQ	1/1:75,12,0:21
-19	15647552	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	16143433	.	T	G	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-19	16143436	.	A	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	16213914	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	16296200	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	16298173	.	C	A	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	16304596	.	G	C	3.54	.	DP=2;AF1=0.5001;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=3.25;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,30:29
-19	16471631	.	T	C	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	16548752	.	G	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	16631177	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	16735479	.	G	T	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-19	16737011	.	C	G	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	16751327	.	G	A	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	16800107	.	T	C	3.54	.	DP=3;AF1=0.5;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	17419010	.	C	T	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	17752449	.	T	C	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-19	17767368	.	C	T	152	.	DP=13;AF1=1;CI95=1,1;DP4=0,0,6,7;MQ=36;FQ=-66	GT:PL:GQ	1/1:185,39,0:75
-19	17767372	.	G	A	161	.	DP=13;AF1=1;CI95=1,1;DP4=0,0,6,7;MQ=36;FQ=-66	GT:PL:GQ	1/1:194,39,0:75
-19	18001132	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	18001229	.	G	C	13.9	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-33	GT:PL:GQ	1/1:45,6,0:10
-19	18001743	.	A	G	3.02	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:30,3,0:4
-19	18001767	.	T	C	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-19	18195972	.	C	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	18484588	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	18664889	.	A	ATG	27.5	.	INDEL;DP=11;AF1=0.5016;CI95=0.5,0.5;DP4=0,1,0,4;MQ=35;FQ=-12.8;PV4=1,0.18,0.34,0.42	GT:PL:GQ	0/1:65,0,22:25
-19	18671826	.	T	C	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-19	18703713	.	T	G	4.13	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:32,3,0:3
-19	20260046	.	C	A	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	20449580	.	A	T	4.13	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:32,3,0:3
-19	20452978	.	GCC	GCCC	102	.	INDEL;DP=13;AF1=0.5;CI95=0.5,0.5;DP4=2,1,1,5;MQ=37;FQ=32.5;PV4=0.23,1,1,2.4e-05	GT:PL:GQ	0/1:140,0,67:70
-19	20454525	.	C	G	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	20697944	.	G	GC	106	.	INDEL;DP=13;AF1=0.6243;CI95=0.5,1;DP4=0,1,9,1;MQ=36;FQ=-30.5;PV4=0.18,0.19,0.38,0.11	GT:PL:GQ	0/1:143,0,4:7
-19	20699318	.	A	T	34.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,3,1;MQ=34;FQ=-39	GT:PL:GQ	1/1:67,12,0:21
-19	20705340	.	G	GATT	28.5	.	INDEL;DP=5;AF1=0.5008;CI95=0.5,0.5;DP4=1,0,3,0;MQ=34;FQ=-9.98;PV4=1,0.13,0.33,0.0037	GT:PL:GQ	0/1:66,0,25:28
-19	20705889	.	A	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	20711314	.	TGG	TGGGG	17.5	.	INDEL;DP=10;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=33;FQ=-43.5	GT:PL:GQ	1/1:57,9,0:15
-19	20711316	.	G	GGT	89.6	.	INDEL;DP=8;AF1=1;CI95=0.5,1;DP4=0,0,6,0;MQ=35;FQ=-52.5	GT:PL:GQ	1/1:130,18,0:33
-19	20711320	.	G	C	32.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,4,0;MQ=37;FQ=-39	GT:PL:GQ	1/1:65,12,0:21
-19	20715519	.	G	A	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-19	20717383	.	G	GAACT	25.5	.	INDEL;DP=12;AF1=0.5;CI95=0.5,0.5;DP4=1,4,0,3;MQ=36;FQ=28.5;PV4=1,0.48,0.11,0.0065	GT:PL:GQ	0/1:63,0,130:66
-19	21354909	.	G	A	12.2	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,0,3;MQ=33;FQ=-36	GT:PL:GQ	1/1:44,9,0:14
-19	21467193	.	ACCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTC	ACCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTC	63	.	INDEL;DP=52;AF1=1;CI95=0.5,1;DP4=0,0,1,3;MQ=37;FQ=-46.5	GT:PL:GQ	1/1:103,12,0:21
-19	21470903	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	21470906	.	T	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	21486985	.	T	C	28	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,2;MQ=37;FQ=-36	GT:PL:GQ	1/1:60,9,0:16
-19	21486986	.	A	AG	65.4	.	INDEL;DP=4;AF1=1;CI95=0.5,1;DP4=0,0,1,2;MQ=37;FQ=-43.5	GT:PL:GQ	1/1:105,9,0:16
-19	21736204	.	C	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	21744637	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	21764018	.	T	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	21789476	.	G	T	12	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:43,6,0:9
-19	21798928	.	C	A	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	21897216	.	A	G	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-19	21917388	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	21919108	.	AGG	AGGG	14.8	.	INDEL;DP=6;AF1=0.5263;CI95=0.5,1;DP4=1,0,1,1;MQ=37;FQ=-24.5;PV4=1,1,1,0	GT:PL:GQ	0/1:52,0,10:13
-19	21936202	.	A	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	22011899	.	A	G	96.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,3,1;MQ=37;FQ=-39	GT:PL:GQ	1/1:129,12,0:21
-19	22011902	.	A	C	48.5	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,3,1;MQ=37;FQ=-39	GT:PL:GQ	1/1:81,12,0:21
-19	22011911	.	A	T	67.3	.	DP=5;AF1=1;CI95=0.5,1;DP4=0,0,4,1;MQ=37;FQ=-42	GT:PL:GQ	1/1:100,15,0:27
-19	22011974	.	G	A	222	.	DP=37;AF1=1;CI95=1,1;DP4=0,0,17,18;MQ=37;FQ=-132	GT:PL:GQ	1/1:255,105,0:99
-19	22012019	.	T	C	201	.	DP=44;AF1=1;CI95=1,1;DP4=0,0,23,21;MQ=37;FQ=-159	GT:PL:GQ	1/1:234,132,0:99
-19	22012051	.	A	G	165	.	DP=35;AF1=1;CI95=1,1;DP4=0,0,15,19;MQ=37;FQ=-129	GT:PL:GQ	1/1:198,102,0:99
-19	22012155	.	T	A	193	.	DP=24;AF1=1;CI95=1,1;DP4=0,0,16,8;MQ=36;FQ=-99	GT:PL:GQ	1/1:226,72,0:99
-19	22012157	.	C	G	158	.	DP=24;AF1=1;CI95=1,1;DP4=0,0,16,7;MQ=36;FQ=-96	GT:PL:GQ	1/1:191,69,0:99
-19	22012166	.	G	C	146	.	DP=11;AF1=1;CI95=1,1;DP4=0,0,6,5;MQ=35;FQ=-60	GT:PL:GQ	1/1:179,33,0:63
-19	22012217	.	T	C	222	.	DP=17;AF1=1;CI95=1,1;DP4=0,0,7,8;MQ=36;FQ=-72	GT:PL:GQ	1/1:255,45,0:87
-19	22012250	.	A	G	179	.	DP=25;AF1=1;CI95=1,1;DP4=0,0,8,16;MQ=36;FQ=-99	GT:PL:GQ	1/1:212,72,0:99
-19	22012307	.	T	C	222	.	DP=22;AF1=1;CI95=1,1;DP4=0,0,6,16;MQ=36;FQ=-93	GT:PL:GQ	1/1:255,66,0:99
-19	22012325	.	A	C	217	.	DP=12;AF1=1;CI95=1,1;DP4=0,0,4,7;MQ=36;FQ=-60	GT:PL:GQ	1/1:250,33,0:63
-19	22012430	.	T	C	222	.	DP=24;AF1=1;CI95=1,1;DP4=0,0,6,17;MQ=37;FQ=-96	GT:PL:GQ	1/1:255,69,0:99
-19	22012579	.	T	A	222	.	DP=42;AF1=1;CI95=1,1;DP4=0,0,26,15;MQ=37;FQ=-150	GT:PL:GQ	1/1:255,123,0:99
-19	22012727	.	C	T	222	.	DP=21;AF1=1;CI95=1,1;DP4=0,0,8,13;MQ=37;FQ=-90	GT:PL:GQ	1/1:255,63,0:99
-19	22012748	.	A	G	30.5	.	DP=18;AF1=1;CI95=0.5,1;DP4=0,0,3,1;MQ=37;FQ=-39	GT:PL:GQ	1/1:63,12,0:21
-19	22012751	.	T	C	24	.	DP=17;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=37;FQ=-36	GT:PL:GQ	1/1:56,9,0:15
-19	22012760	.	C	T	222	.	DP=16;AF1=1;CI95=1,1;DP4=0,0,5,10;MQ=36;FQ=-72	GT:PL:GQ	1/1:255,45,0:87
-19	22128042	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	22376925	.	G	A	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	22516053	.	A	G	54	.	DP=9;AF1=1;CI95=1,1;DP4=0,0,3,5;MQ=36;FQ=-51	GT:PL:GQ	1/1:87,24,0:45
-19	23130188	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	23216070	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	23216752	.	T	G	6.02	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=32;FQ=-33	GT:PL:GQ	1/1:36,6,0:6
-19	23216754	.	G	A	13	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=32;FQ=-33	GT:PL:GQ	1/1:44,6,0:9
-19	23225184	.	C	T	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	23239936	.	C	A	5.46	.	DP=19;AF1=0.4999;CI95=0.5,0.5;DP4=5,1,0,6;MQ=35;FQ=7.8;PV4=0.015,0.00042,0.072,1	GT:PL:GQ	0/1:34,0,116:34
-19	23281456	.	A	G	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	23309145	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	23309152	.	T	C	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	23383229	.	C	G	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=0,1,0,1;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	23399342	.	T	C	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-19	23418245	.	G	T	40	.	DP=5;AF1=0.5016;CI95=0.5,0.5;DP4=1,0,1,3;MQ=37;FQ=-6.18;PV4=0.4,0.014,1,0.043	GT:PL:GQ	0/1:70,0,22:25
-19	23418278	.	T	A	88.1	.	DP=6;AF1=1;CI95=0.5,1;DP4=0,0,3,3;MQ=37;FQ=-45	GT:PL:GQ	1/1:121,18,0:33
-19	23418327	.	A	G	43.1	.	DP=7;AF1=1;CI95=0.5,1;DP4=0,0,2,4;MQ=37;FQ=-45	GT:PL:GQ	1/1:76,18,0:33
-19	23418353	.	G	C	68	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=37;FQ=-36	GT:PL:GQ	1/1:100,9,0:16
-19	23418485	.	T	C	50.1	.	DP=7;AF1=1;CI95=1,1;DP4=0,0,5,2;MQ=36;FQ=-48	GT:PL:GQ	1/1:83,21,0:39
-19	23418549	.	G	A	17.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:49,6,0:10
-19	23418558	.	G	A	12	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:43,6,0:9
-19	23476446	.	G	A	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-19	23750472	.	TGCAG	TG	112	.	INDEL;DP=41;AF1=0.5;CI95=0.5,0.5;DP4=17,13,4,5;MQ=37;FQ=115;PV4=0.71,0.16,1,1	GT:PL:GQ	0/1:150,0,255:99
-19	23750625	.	A	G	139	.	DP=52;AF1=1;CI95=1,1;DP4=0,0,29,22;MQ=37;FQ=-181	GT:PL:GQ	1/1:172,154,0:99
-19	23800889	.	TA	T	7.35	.	INDEL;DP=11;AF1=0.5;CI95=0.5,0.5;DP4=5,3,1,1;MQ=37;FQ=9.94;PV4=1,0.075,1,1	GT:PL:GQ	0/1:44,0,193:45
-19	24001511	.	A	C	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	24021577	.	A	G	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	24054562	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	24069383	.	T	A	27.8	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:59,6,0:10
-19	24125925	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	24191462	.	G	A	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	24196752	.	C	G	8.44	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=32;FQ=-33	GT:PL:GQ	1/1:39,6,0:8
-19	24199057	.	C	T	6.02	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=25;FQ=-33	GT:PL:GQ	1/1:36,6,0:6
-19	24199212	.	CT	CTT	18.5	.	INDEL;DP=9;AF1=0.5;CI95=0.5,0.5;DP4=1,1,1,1;MQ=37;FQ=18.5;PV4=1,1,1,0.027	GT:PL:GQ	0/1:56,0,56:56
-19	24205962	.	ACC	AC	14.4	.	INDEL;DP=5;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:53,6,0:10
-19	24209339	.	CT	CTT	11.5	.	INDEL;DP=8;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=32;FQ=-40.5	GT:PL:GQ	1/1:50,6,0:9
-19	24276126	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	24297919	.	C	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	24409006	.	G	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	24434846	.	C	G	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-19	24439851	.	C	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	25085208	.	C	T	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-19	25088621	.	A	C	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-19	25152568	.	AG	A	13.4	.	INDEL;DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:52,6,0:9
-19	25176862	.	C	T	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	25202314	.	G	T	3.57	.	DP=2;AF1=0.5048;CI95=0.5,0.5;DP4=0,1,1,0;MQ=37;FQ=-10.6;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,17:23
-19	25264826	.	T	A	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-19	25568427	.	A	G	28	.	DP=4;AF1=1;CI95=0.5,1;DP4=0,0,0,3;MQ=25;FQ=-36	GT:PL:GQ	1/1:60,9,0:16
-19	25568441	.	G	A	89	.	DP=10;AF1=1;CI95=1,1;DP4=0,0,7,3;MQ=29;FQ=-57	GT:PL:GQ	1/1:122,30,0:57
-19	25568480	.	A	G	169	.	DP=11;AF1=1;CI95=1,1;DP4=0,0,8,3;MQ=30;FQ=-60	GT:PL:GQ	1/1:202,33,0:63
-19	25568513	.	T	A	124	.	DP=9;AF1=1;CI95=1,1;DP4=0,0,6,3;MQ=28;FQ=-54	GT:PL:GQ	1/1:157,27,0:51
-19	25568527	.	A	G	109	.	DP=9;AF1=1;CI95=1,1;DP4=0,0,6,3;MQ=28;FQ=-54	GT:PL:GQ	1/1:142,27,0:51
-19	25568536	.	A	G	13.2	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=25;FQ=-36	GT:PL:GQ	1/1:45,9,0:14
-19	25581569	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	26697796	.	T	A	6.2	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:35,3,0:4
-19	26728829	.	AGG	ATGG,AG	8.83	.	INDEL;DP=5;AF1=1;CI95=0.5,1;DP4=0,0,0,3;MQ=33;FQ=-40.5	GT:PL:GQ	1/1:71,30,24,46,0,43:8
-19	26747187	.	AGG	AG	14.4	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:53,6,0:10
-19	26751288	.	G	GAC	116	.	INDEL;DP=8;AF1=1;CI95=0.5,1;DP4=0,0,5,1;MQ=35;FQ=-52.5	GT:PL:GQ	1/1:156,18,0:33
-19	26756358	.	CA	CAAA	11.8	.	INDEL;DP=6;AF1=0.5;CI95=0.5,0.5;DP4=1,1,1,1;MQ=37;FQ=14.4;PV4=1,0.41,1,0.0024	GT:PL:GQ	0/1:49,0,62:51
-19	26758413	.	GT	GTT	52.4	.	INDEL;DP=6;AF1=1;CI95=0.5,1;DP4=0,0,3,0;MQ=37;FQ=-43.5	GT:PL:GQ	1/1:92,9,0:16
-19	26764380	.	C	T	13	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-33	GT:PL:GQ	1/1:44,6,0:9
-19	26765941	.	AGG	AGGGG	24.2	.	INDEL;DP=5;AF1=1;CI95=0.5,1;DP4=0,0,1,1;MQ=37;FQ=-40.5	GT:PL:GQ	1/1:63,6,0:10
-19	26780556	.	A	AC	18.3	.	INDEL;DP=3;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=32;FQ=-40.5	GT:PL:GQ	1/1:57,6,0:10
-19	26787476	.	G	A	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	26803166	.	A	G	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	26803281	.	G	T	7.8	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	1/1:37,3,0:4
-19	26827257	.	G	A	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	26847473	.	A	C	10.2	.	DP=2;AF1=1;CI95=0.5,1;DP4=0,0,0,2;MQ=37;FQ=-33	GT:PL:GQ	1/1:41,6,0:8
-19	26852064	.	TACACACACACACACACACACACACACACACACACACACA	TACACACACACACACACACACACACACACACACACACA	118	.	INDEL;DP=55;AF1=0.5;CI95=0.5,0.5;DP4=8,10,4,6;MQ=37;FQ=121;PV4=1,1,1,1	GT:PL:GQ	0/1:156,0,255:99
-19	27313337	.	G	A	3.41	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,0;MQ=37;FQ=-33	GT:PL:GQ	1/1:32,6,0:4
-19	27314462	.	T	C	40	.	DP=3;AF1=1;CI95=0.5,1;DP4=0,0,2,1;MQ=37;FQ=-36	GT:PL:GQ	1/1:72,9,0:16
-19	27466173	.	C	G	3.54	.	DP=2;AF1=0.5;CI95=0.5,0.5;DP4=1,0,1,0;MQ=37;FQ=3.54;PV4=1,1,1,1	GT:PL:GQ	0/1:31,0,31:29
-19	28220602	.	T	G	222	.	DP=21;AF1=1;CI95=1,1;DP4=0,0,8,13;MQ=37;FQ=-90	GT:PL:GQ	1/1:255,63,0:99
-19	28220622	.	C	T	222	.	DP=21;AF1=1;CI95=1,1;DP4=0,0,8,13;MQ=37;FQ=-90	GT:PL:GQ	1/1:255,63,0:99
-19	28220668	.	G	A	222	.	DP=13;AF1=1;CI95=1,1;DP4=0,0,5,6;MQ=36;FQ=-60	GT:PL:GQ	1/1:255,33,0:63
-19	28220691	.	T	C	148	.	DP=7;AF1=1;CI95=1,1;DP4=0,0,3,4;MQ=36;FQ=-48	GT:PL:GQ	1/1:181,21,0:39
-19	28486996	.	T	C	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-19	28643319	.	C	T	3.55	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:31,3,0:4
-19	28643329	.	C	T	4.77	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,1,0;MQ=37;FQ=-30	GT:PL:GQ	0/1:33,3,0:3
-19	28714335	.	C	A	6.98	.	DP=1;AF1=1;CI95=0.5,1;DP4=0,0,0,1;MQ=37;FQ=-30	GT:PL:GQ	1/1:36,3,0:4
-19	28837706	.	A	T	154	.	DP=13;AF1=1;CI95=1,1;DP4=0,0,3,10;MQ=25;FQ=-66	GT:PL:GQ	1/1:187,39,0:75
-19	28837717	.	G	A	154	.	DP=13;AF1=1;CI95=1,1;DP4=0,0,3,10;MQ=25;FQ=-66	GT:PL:GQ	1/1:187,39,0:75
-19	28837735	.	A	G	154	.	DP=24;AF1=1;CI95=1,1;DP4=0,0,7,14;MQ=25;FQ=-90	GT:PL:GQ	1/1:187,63,0:99
-19	28837767	.	A	G,T	177	.	DP=53;AF1=1;CI95=1,1;DP4=0,0,21,29;MQ=30;FQ=-175	GT:PL:GQ	1/1:210,148,0,204,125,201:99
-19	28837787	.	C	T	161	.	DP=66;AF1=1;CI95=1,1;DP4=0,1,30,35;MQ=31;FQ=-206;PV4=1,1,1,1	GT:PL:GQ	1/1:194,179,0:99
-19	28837805	.	A	G	222	.	DP=54;AF1=1;CI95=1,1;DP4=0,0,26,26;MQ=32;FQ=-184	GT:PL:GQ	1/1:255,157,0:99
--- a/tool-data/snpeff_annotations.loc.sample	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,5 +0,0 @@
-## Regulation Databases for SnpEff 
-## These are from the list on: http://snpeff.sourceforge.net/download.html
-#genome	annotation_name description
-#GRCh37.71	nextprot	nextprot
-#GRCh37.71	motif	motif
--- a/tool-data/snpeff_databases.loc.sample	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,5 +0,0 @@
-## Available Databases for SnpEff 
-## These are from the list on: http://snpeff.sourceforge.net/download.html
-## the Description field in this sample is "Genome : Version" 
-#Version	Description
-#GRCh37.68	Homo sapiens : GRCh37.68
--- a/tool-data/snpeff_genomedb.loc.sample	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,5 +0,0 @@
-## Downloaded Databases for SnpEff 
-## These are from the list on: http://snpeff.sourceforge.net/download.html
-## the Description field in this sample is "Genome : Version" 
-#Version        Description	data_dir path
-#GRCh37.68      Homo sapiens : GRCh37.68	/home/galaxy/snpEff/data
--- a/tool-data/snpeff_regulationdb.loc.sample	Wed Dec 11 08:53:32 2013 -0500
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,4 +0,0 @@
-## Regulation Databases for SnpEff 
-## These are from the list on: http://snpeff.sourceforge.net/download.html
-#genome	regulation_name description
-#GRCh37.70	CD4	CD4
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool-data/snpeffv_annotations.loc.sample	Thu Jan 22 08:28:37 2015 -0500
@@ -0,0 +1,5 @@
+## Regulation Databases for SnpEff 
+## These are from the list on: http://snpeff.sourceforge.net/download.html
+#key	snpeff_version	genome	annotation_name description
+#SnpEff4.0_GRCh37.75	SnpEff4.0	GRCh37.75	nextprot	nextprot
+#SnpEff4.0_GRCh38.76	SnpEff4.1	GRCh38.76	motif	motif
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool-data/snpeffv_databases.loc.sample	Thu Jan 22 08:28:37 2015 -0500
@@ -0,0 +1,5 @@
+## Available Databases for SnpEff 
+## These are from the list on: http://snpeff.sourceforge.net/download.html
+## the Description field in this sample is "Genome : Version" 
+#key	snpeff_version	Version	Description
+#SnpEff4.0_GRCh37.75	SnpEff4.0	GRCh37.75	Homo sapiens : GRCh37.75
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool-data/snpeffv_genomedb.loc.sample	Thu Jan 22 08:28:37 2015 -0500
@@ -0,0 +1,6 @@
+## Downloaded Databases for SnpEff 
+## These are from the list on: http://snpeff.sourceforge.net/download.html
+## the Description field in this sample is "Genome : Version" 
+#Key	snpeff_version	Version	Description	data_dir	path
+#SnpEff4.0_GRCh37.74	SnpEff4.0	GRCh37.74	Homo sapiens : GRCh37.74	/home/galaxy/snpEff/v4_0/data
+#SnpEff4.1_GRCh38.76	SnpEff4.1	GRCh38.76	Homo sapiens : GRCh38.76	/home/galaxy/snpEff/v4_1/data
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool-data/snpeffv_regulationdb.loc.sample	Thu Jan 22 08:28:37 2015 -0500
@@ -0,0 +1,5 @@
+## Regulation Databases for SnpEff 
+## These are from the list on: http://snpeff.sourceforge.net/download.html
+#Key	snpeff_version	genome	regulation_name description
+#SnpEff4.0_GRCh37.74	SnpEff4.0	GRCh37.74	CD4	CD4
+#SnpEff4.1_GRCh38.76	SnpEff4.1	GRCh38.76	CD4	CD4
--- a/tool_data_table_conf.xml.sample	Wed Dec 11 08:53:32 2013 -0500
+++ b/tool_data_table_conf.xml.sample	Thu Jan 22 08:28:37 2015 -0500
@@ -1,19 +1,19 @@
 <tables>
-    <table name="snpeff_databases" comment_char="#">
-        <columns>value, name</columns>
-        <file path="tool-data/snpeff_databases.loc" />
+    <table name="snpeffv_genomedb" comment_char="#">
+        <columns>key, version, value, name, path</columns>
+        <file path="tool-data/snpeffv_genomedb.loc" />
     </table>
-    <table name="snpeff_genomedb" comment_char="#">
-        <columns>value, name, path</columns>
-        <file path="tool-data/snpeff_genomedb.loc" />
+    <table name="snpeffv_regulationdb" comment_char="#">
+        <columns>key, version, genome, value, name</columns>
+        <file path="tool-data/snpeffv_regulationdb.loc" />
     </table>
-    <table name="snpeff_regulationdb" comment_char="#">
-        <columns>genome, value, name</columns>
-        <file path="tool-data/snpeff_regulationdb.loc" />
+    <table name="snpeffv_annotations" comment_char="#">
+        <columns>key, version, genome, value, name</columns>
+        <file path="tool-data/snpeffv_annotations.loc" />
     </table>
-    <table name="snpeff_annotations" comment_char="#">
-        <columns>genome, value, name</columns>
-        <file path="tool-data/snpeff_annotations.loc" />
+    <table name="snpeffv_databases" comment_char="#">
+        <columns>key, version, value, name</columns>
+        <file path="tool-data/snpeffv_databases.loc" />
     </table>
 </tables>
 
--- a/tool_dependencies.xml	Wed Dec 11 08:53:32 2013 -0500
+++ b/tool_dependencies.xml	Thu Jan 22 08:28:37 2015 -0500
@@ -1,7 +1,7 @@
 <?xml version="1.0"?>
 <tool_dependency>
-    <package name="snpEff" version="3.4">
-        <repository toolshed="http://toolshed.g2.bx.psu.edu" name="package_snpeff_3_4" owner="iuc" changeset_revision="af7ff8187d09" />
+    <package name="snpEff" version="4.0">
+        <repository name="package_snpeff_4_0" owner="iuc" changeset_revision="6bc55957927b" toolshed="http://toolshed.g2.bx.psu.edu" />
     </package>
 </tool_dependency>