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author laurenmarazzi
date Wed, 22 Dec 2021 16:00:34 +0000
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p38alpha	-	TAB1
AKT	+	CFLAR
ITCH	-	CFLAR
AKT	+	IKKA
DKK1gene	+	DKK1
AKT	-	pras40
LRP	-	Axin
betacatenin	+	TCF
NLK	-	TCF
TCF	+	cMYC
FOXO	+	RTPKgene
GSK3	+	TSC2
IKKB	-	TSC2
AKT	-	TSC2
RSK	-	TSC2
ERK	-	TSC2
cMYC	-	SFRP1gene
CytochromeC	+	Caspase9
p38alpha	+	p53
MDM2	-	p53
TCF	+	DKK1gene
cMYC	-	DKK1gene
GRB2	+	GAB
ERK	-	GAB
PDK1	+	AKT
mTORC2	+	AKT
AKT	-	ASK1
ERK	+	RSK
PDK1	+	RSK
GAB	+	SHP2
SOS	+	Ras
SHP2	+	Ras
Rac	+	MEKK4
PDK1	+	S6K
mTORC1	+	S6K
ASK1	+	MKK3
TAK1	+	MKK3
PI3K	+	PDK1
PTEN	-	PDK1
Raf	+	MEK
MAP3K8	+	MEK
ERK	-	MEK
p38alpha	+	DUSP1
MSK	+	DUSP1
AKT	-	BAD
RSK	-	BAD
p53	+	BAX
TAB1	+	TAK1
RTPKgene	+	RTPK
MMP	+	RTPK
p38alpha	-	RTPK
MEK	-	RTPK
LRP	-	CK1
TCF	-	Egr1
GRB2	+	SOS
ERK	-	SOS
BAD	-	BCL2
TAK1	+	MKK7
GRAP2	+	MKK7
Fz	+	LRP
ERK	+	LRP
JNK1	+	LRP
p38alpha	+	LRP
DKK1	-	LRP
SHC1	+	GRB2
IKKB	+	MAP3K8
CFLAR	-	Caspase8
AKT	-	FOXO
NLK	-	FOXO
LRP	-	GSK3
RSK	-	GSK3
S6K	-	GSK3
ERK	-	GSK3
p38alpha	-	GSK3
Dvl	-	GSK3
AKT	-	GSK3
Ras	+	Raf
Rheb	-	Raf
AKT	-	Raf
ERK	-	Raf
JNK1	+	ITCH
Rac	+	MLK3
Egr1	+	PTENgene
MKK3	+	p38alpha
MKK4	+	p38alpha
DUSP1	-	p38alpha
TAK1	+	IKKB
p53	-	IKKB
ERK	+	MSK
p38alpha	+	MSK
AKT	+	MDM2
MDM2gene	+	MDM2
S6K	-	MDM2
NFkB	+	MDM2gene
p53	+	MDM2gene
ERK	+	DUSP6
mTORC1	+	DUSP6
IKKA	+	NFkB
IKKB	+	NFkB
MSK	+	NFkB
MKK7	+	JNK1
MKK4	+	JNK1
DUSP1	-	JNK1
MEK	+	ERK
DUSP6	-	ERK
TSC2	-	Rheb
Dvl	+	Rac
mTORC2	+	Rac
BAX	+	CytochromeC
BCL2	-	CytochromeC
IKKA	+	betacatenin
betaTrCP	-	betacatenin
MEKK4	+	MKK4
MLK3	+	MKK4
TAK1	+	MKK4
GRAP2	+	MKK4
TSC2	+	mTORC2
S6K	-	mTORC2
RTPK	+	SHC1
PTEN	-	SHC1
S6K	-	IRS1
ERK	-	IRS1
IKKB	-	IRS1
Rheb	+	mTORC1
RSK	+	mTORC1
pras40	-	mTORC1
TAK1	+	NLK
Fz	+	Dvl
Axin	+	betaTrCP
GSK3	+	betaTrCP
CK1	+	betaTrCP
SFRP1gene	+	SFRP1
SFRP1	-	Fz
LEF	+	MMP
GAB	+	PI3K
IRS1	+	PI3K
Ras	+	PI3K
betacatenin	+	LEF
PTENgene	+	PTEN
GSK3	-	PTEN
p38alpha	-	GRAP2
RSK	+	CCND1
TCF	+	CCND1
Caspase8	+	Caspase37
Caspase9	+	Caspase37
Caspase37	+	Antisurvival
FOXO	+	Antisurvival
CCND1	+	Prosurvival
cMYC	+	Prosurvival