Mercurial > repos > metexplore > met4j

<?xml version="1.0" encoding="UTF-8" standalone="no"?>
<tool id="met4j_ChokePoint" name="ChokePoint" version="2.0.1">
  <description>Compute the Choke points of a metabolic network.</description>
  <xrefs>
    <xref type="bio.tools">met4j</xref>
  </xrefs>
  <requirements>
    <container type="singularity">oras://registry.forgemia.inra.fr/metexplore/met4j/met4j-singularity:2.0.1</container>
  </requirements>
  <command detect_errors="exit_code"><![CDATA[sh /usr/bin/met4j.sh networkAnalysis.ChokePoint -i "$inputPath"
 -o "$outputPath"
]]></command>
  <inputs>
    <param argument="-i" format="sbml" label="input SBML file" name="inputPath" optional="false" type="data" value=""/>
  </inputs>
  <outputs>
    <data format="tsv" name="outputPath"/>
  </outputs>
  <tests>
    <test>

      <param name="inputPath" value="XF_network.sbml"/>

      <output ftype="tsv" name="outputPath">

        <assert_contents>

          <has_n_lines n="695"/>

          <has_n_columns n="3"/>

          <has_line_matching expression="R_ADEtex.*adenine_transport_via_diffusion__extracellular_to_periplasm_.*M_ade_e &lt;==&gt; M_ade_p" n="1"/>

          <has_line_matching expression="R_AGDC_r.*R_AGDC_r.*M_acgam6p_c \+ M_h2o_c --&gt; M_ac_c \+ M_gam6p_c" n="1"/>

        </assert_contents>

      </output>

    </test>
  </tests>
  <help><![CDATA[Compute the Choke points of a metabolic network.
Choke points are reactions that are required to consume or produce one compound. Targeting of choke point can lead to the accumulation or the loss of some metabolites, thus choke points constitute an indicator of lethality and can help identifying drug target.]]></help>
  <citations>
    <citation type="doi">10.1093/bioinformatics/btl181</citation>
  </citations>
</tool>
author	metexplore
date	Thu, 13 Feb 2025 15:08:22 +0000
parents	6a112eaf8f38
children