annotate offspring_heterozygosity_pedigree.py @ 39:e56023008e36 default tip

Changed revision of package_fisher_0_1_4 to be2fc454d121 Changed revision of package_matplotlib_1_2 to a03ee94316b5
author miller-lab
date Mon, 06 Jul 2015 10:32:24 -0400
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1 #!/usr/bin/env python
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2
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3 import sys
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4 import gd_util
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5
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6 from Population import Population
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7
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8 def load_and_check_pop(file, total_pop, name):
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9 p = Population()
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10 p.from_population_file(file)
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11 if not total_pop.is_superset(p):
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12 gd_util.die('There is an individual in the {0} that is not in the SNP table'.format(name))
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13 return p
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15 def append_breeders_from_file(the_list, filename, kind):
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16 with open(filename) as fh:
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17 for line in fh:
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18 elems = line.split()
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19 breeder = elems[0].rstrip('\r\n')
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20 the_list.append('{0}:{1}'.format(kind, breeder))
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22 ################################################################################
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24 if len(sys.argv) != 9:
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25 gd_util.die('Usage')
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27 input, input_type, pedigree, ind_arg, founders, b1_input, b2_input, output = sys.argv[1:]
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29 p_total = Population()
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30 p_total.from_wrapped_dict(ind_arg)
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32 f1 = load_and_check_pop(founders, p_total, 'founders')
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34 ################################################################################
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35
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36 prog = 'offspring_heterozygosity2'
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38 args = [ prog ]
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39 args.append(input) # a Galaxy SNP table
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40 args.append(pedigree) # a pedigree, where the SNP table is for the founders
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42 for tag in f1.tag_list():
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43 column, name = tag.split(':')
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44 if type == 'gd_genotype':
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45 column = int(column) - 2
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46 tag = 'founder:{0}:{1}'.format(column, name)
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47 args.append(tag)
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49 append_breeders_from_file(args, b1_input, 0)
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50 append_breeders_from_file(args, b2_input, 1)
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52 with open(output, 'w') as fh:
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53 gd_util.run_program(prog, args, stdout=fh)
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54
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55 ################################################################################
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56
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57 sys.exit(0)
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58