Mercurial > repos > miller-lab > genome_diversity
annotate offspring_heterozygosity_pedigree.py @ 39:e56023008e36 default tip
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author | miller-lab |
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date | Mon, 06 Jul 2015 10:32:24 -0400 |
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1 #!/usr/bin/env python |
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2 |
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3 import sys |
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4 import gd_util |
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5 |
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6 from Population import Population |
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7 |
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8 def load_and_check_pop(file, total_pop, name): |
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9 p = Population() |
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10 p.from_population_file(file) |
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11 if not total_pop.is_superset(p): |
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12 gd_util.die('There is an individual in the {0} that is not in the SNP table'.format(name)) |
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13 return p |
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14 |
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15 def append_breeders_from_file(the_list, filename, kind): |
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16 with open(filename) as fh: |
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17 for line in fh: |
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18 elems = line.split() |
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19 breeder = elems[0].rstrip('\r\n') |
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20 the_list.append('{0}:{1}'.format(kind, breeder)) |
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21 |
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22 ################################################################################ |
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23 |
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24 if len(sys.argv) != 9: |
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25 gd_util.die('Usage') |
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26 |
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27 input, input_type, pedigree, ind_arg, founders, b1_input, b2_input, output = sys.argv[1:] |
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28 |
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29 p_total = Population() |
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30 p_total.from_wrapped_dict(ind_arg) |
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32 f1 = load_and_check_pop(founders, p_total, 'founders') |
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34 ################################################################################ |
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36 prog = 'offspring_heterozygosity2' |
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38 args = [ prog ] |
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39 args.append(input) # a Galaxy SNP table |
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40 args.append(pedigree) # a pedigree, where the SNP table is for the founders |
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41 |
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42 for tag in f1.tag_list(): |
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43 column, name = tag.split(':') |
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44 if type == 'gd_genotype': |
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45 column = int(column) - 2 |
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46 tag = 'founder:{0}:{1}'.format(column, name) |
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47 args.append(tag) |
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48 |
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49 append_breeders_from_file(args, b1_input, 0) |
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50 append_breeders_from_file(args, b2_input, 1) |
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51 |
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52 with open(output, 'w') as fh: |
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53 gd_util.run_program(prog, args, stdout=fh) |
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54 |
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55 ################################################################################ |
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57 sys.exit(0) |
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58 |