comparison build_protein_interaction_maps.xml @ 1:0a85d709c4ae draft

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author proteore
date Tue, 12 Mar 2019 07:02:14 -0400
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children 99f6a94c1ade
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0:b0ac71686b99 1:0a85d709c4ae
1 <tool id="build_protein_interaction_maps" name="Build Protein-Protein interaction network" version="2019.03.08"> 1 <tool id="build_protein_interaction_maps" name="Build Protein-Protein interaction network" version="2019.03.12.2">
2 <description>[BioGRID, BioPlex, HuMAP]</description> 2 <description>[BioGRID, BioPlex, HuMAP]</description>
3 <requirements> 3 <requirements>
4 </requirements> 4 </requirements>
5 <command detect_errors="exit_code"><![CDATA[ 5 <command detect_errors="exit_code"><![CDATA[
6 python $__tool_directory__/build_protein_interaction_maps.py 6 python $__tool_directory__/build_protein_interaction_maps.py
144 144
145 Two output files are created with the follwing prefix "Network_PPIdatabaseName\_" and a "Nodes_PPIdatabaseName\_" (where "PPIdatabaseName" correspond to the PPI database selected). 145 Two output files are created with the follwing prefix "Network_PPIdatabaseName\_" and a "Nodes_PPIdatabaseName\_" (where "PPIdatabaseName" correspond to the PPI database selected).
146 The "Network" file contains information related to each interaction between two proteins (one row per binary interaction) while the "Nodes" file contains attributes (i.e. annotation, information) related to each gene/protein. 146 The "Network" file contains information related to each interaction between two proteins (one row per binary interaction) while the "Nodes" file contains attributes (i.e. annotation, information) related to each gene/protein.
147 Below is shown a brief example of each output file when BioGRID is selected. Note that a "NA" is added when there is no available information. 147 Below is shown a brief example of each output file when BioGRID is selected. Note that a "NA" is added when there is no available information.
148 148
149 "Network" output file (example):
150
149 .. csv-table:: Network file (if BioGRID database selected - simulated data) 151 .. csv-table:: Network file (if BioGRID database selected - simulated data)
150 :header: "Entrez_Gene_Interactor_A","Entrez Gene Interactor B","Gene symbol Interactor A","Gene symbol Interactor B","Experimental System","Experimental Type","Pubmed ID","Interaction Score","Phenotypes" 152 :header: "Entrez_Gene_Interactor_A","Entrez Gene Interactor B","Gene symbol Interactor A","Gene symbol Interactor B","Experimental System","Experimental Type","Pubmed ID","Interaction Score","Phenotypes"
151 153
152 1,368,"A1BG","ABCC6","Two-hybrid","physical",21988832,"NA","Growth abnormality" 154 1,368,"A1BG","ABCC6","Two-hybrid","physical",21988832,"NA","Growth abnormality"
153 1,10549,"A1BG","PRDX4","Negative Genetic","genetic",21988832,"NA","NA" 155 1,10549,"A1BG","PRDX4","Negative Genetic","genetic",21988832,"NA","NA"
154 1,9923,"A1BG","ZBTB40","Affinity Capture-MS","physical",28514442,0.99977983,"NA" 156 1,9923,"A1BG","ZBTB40","Affinity Capture-MS","physical",28514442,0.99977983,"NA"
155 157
156 158
157 **"Interaction Score"**: a positive for negative value recorded by the original publication depicting P-Values, Confidence Score, SGA Score, etc. Will be “NA” if no score is reported. 159 **"Interaction Score"**: a positive for negative value recorded by the original publication depicting P-Values, Confidence Score, SGA Score, etc. Will be “NA” if no score is reported.
160
161 "Nodes" output file (example):
158 162
159 .. csv-table:: Nodes file (if BioGRID database selected - simulated data) 163 .. csv-table:: Nodes file (if BioGRID database selected - simulated data)
160 :header: "Entrez gene ID","Official Symbol Interactor","Present in user input ids","ID present in Biogrid Human","Pathway" 164 :header: "Entrez gene ID","Official Symbol Interactor","Present in user input ids","ID present in Biogrid Human","Pathway"
161 165
162 "1","A1BG","True","True","Platelet degranulation ;Neutrophil degranulation" 166 "1","A1BG","True","True","Platelet degranulation ;Neutrophil degranulation"
200 .. class:: infomark 204 .. class:: infomark
201 205
202 **Galaxy integration** 206 **Galaxy integration**
203 207
204 David Christiany, Lisa Perus, Florence Combes, Yves Vandenbrouck - CEA, INSERM, CNRS, Grenoble-Alpes University, BIG Institute, FR 208 David Christiany, Lisa Perus, Florence Combes, Yves Vandenbrouck - CEA, INSERM, CNRS, Grenoble-Alpes University, BIG Institute, FR
209
205 Sandra Dérozier, Olivier Rué, Valentin Loux - INRA, Paris-Saclay University, MAIAGE Unit, Migale Bioinformatics platform, FR 210 Sandra Dérozier, Olivier Rué, Valentin Loux - INRA, Paris-Saclay University, MAIAGE Unit, Migale Bioinformatics platform, FR
211
206 This work has been partially funded through the French National Agency for Research (ANR) IFB project. 212 This work has been partially funded through the French National Agency for Research (ANR) IFB project.
213
207 Contact support@proteore.org for any questions or concerns about the Galaxy implementation of this tool. 214 Contact support@proteore.org for any questions or concerns about the Galaxy implementation of this tool.
208 ]]></help> 215 ]]></help>
209 <citations> 216 <citations>
210 </citations> 217 </citations>
211 </tool> 218 </tool>