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1 package edu.unc.genomics.wigmath;
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2
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3 import java.io.IOException;
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4 import java.util.Iterator;
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5
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6 import org.apache.log4j.Logger;
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7 import org.broad.igv.bbfile.WigItem;
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8
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9 import com.beust.jcommander.Parameter;
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10
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11 import edu.unc.genomics.io.WigFile;
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12 import edu.unc.genomics.io.WigFileException;
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13
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14 public class LogTransform extends WigMathTool {
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15
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16 private static final Logger log = Logger.getLogger(LogTransform.class);
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17
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18 @Parameter(names = {"-i", "--input"}, description = "Input file", required = true)
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19 public WigFile inputFile;
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20 @Parameter(names = {"-b", "--base"}, description = "Logarithm base (default = 2)")
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21 public double base = 2;
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22
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23 private double baseChange;
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24
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25 @Override
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26 public void setup() {
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27 baseChange = Math.log(base);
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28 inputs.add(inputFile);
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29 }
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30
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31 @Override
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32 public float[] compute(String chr, int start, int stop) throws IOException, WigFileException {
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33 log.debug("Computing difference for chunk "+chr+":"+start+"-"+stop);
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34
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35 Iterator<WigItem> data = inputFile.query(chr, start, stop);
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36 float[] result = WigFile.flattenData(data, start, stop);
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37
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38 for (int i = 0; i < result.length; i++) {
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39 result[i] = (float) (Math.log(result[i]) / baseChange);
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40 }
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41
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42 return result;
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43 }
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44
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45
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46 /**
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47 * @param args
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48 * @throws WigFileException
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49 * @throws IOException
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50 */
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51 public static void main(String[] args) throws IOException, WigFileException {
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52 new LogTransform().instanceMain(args);
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53 }
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54
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55 }
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