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1 # Copyright INRA (Institut National de la Recherche Agronomique)
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2 # http://www.inra.fr
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3 # http://urgi.versailles.inra.fr
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4 #
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5 # This software is governed by the CeCILL license under French law and
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6 # abiding by the rules of distribution of free software. You can use,
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7 # modify and/ or redistribute the software under the terms of the CeCILL
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8 # license as circulated by CEA, CNRS and INRIA at the following URL
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9 # "http://www.cecill.info".
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10 #
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11 # As a counterpart to the access to the source code and rights to copy,
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12 # modify and redistribute granted by the license, users are provided only
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13 # with a limited warranty and the software's author, the holder of the
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14 # economic rights, and the successive licensors have only limited
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15 # liability.
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16 #
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17 # In this respect, the user's attention is drawn to the risks associated
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18 # with loading, using, modifying and/or developing or reproducing the
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19 # software by the user in light of its specific status of free software,
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20 # that may mean that it is complicated to manipulate, and that also
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21 # therefore means that it is reserved for developers and experienced
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22 # professionals having in-depth computer knowledge. Users are therefore
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23 # encouraged to load and test the software's suitability as regards their
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24 # requirements in conditions enabling the security of their systems and/or
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25 # data to be ensured and, more generally, to use and operate it in the
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26 # same conditions as regards security.
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27 #
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28 # The fact that you are presently reading this means that you have had
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29 # knowledge of the CeCILL license and that you accept its terms.
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30
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31 import os
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32 import json
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33 from collections import OrderedDict
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34 from commons.tools.RenameHeaderClassif import RenameHeaderClassif
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35
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36 class ClassifUtils(object):
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37
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38 @staticmethod
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39 def _formatProfilesResultsAsDict(lProfilesResults):
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40 if len(lProfilesResults) == 0:
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41 return OrderedDict()
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42
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43 dResults = OrderedDict()
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44
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45 for refNameAndCoverage in lProfilesResults:
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46 refName, coverage = refNameAndCoverage.split(": ")
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47
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48 coverage = coverage.split("%(")
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49 coverageOnSubject = float(coverage.pop(1).replace("%)", ""))
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50 coverage = float(coverage.pop(0))
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51
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52 profilesResult = OrderedDict()
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53 profilesResult["cov"] = coverage
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54 profilesResult["covOnSubject"] = coverageOnSubject
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55 dResults[refName] = profilesResult
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56 return dResults
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57
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58 @staticmethod
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59 def _formatCodingFeaturesAsDict(lineOfEvidence, dCoding):
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60 codingEvidences = lineOfEvidence.split("; ")
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61
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62 for codingTypeData in codingEvidences:
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63 codingTypeData = codingTypeData.split(": ")
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64 codingType = codingTypeData.pop(0)
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65
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66 codingTypeData = ": ".join(codingTypeData)
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67 codingTypeData = codingTypeData.split(", ")
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68
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69 if codingType == "TE_BLRtx":
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70 if not dCoding.has_key("TE_BLRtx"):
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71 dCoding["TE_BLRtx"] = OrderedDict()
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72 for refNameAndCoverage in codingTypeData:
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73 blrtxResult = OrderedDict()
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74 refName, coverage = refNameAndCoverage.rsplit(": ", 1)
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75 coverage = float(coverage.replace("%", ""))
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76 blrtxResult["cov"] = coverage
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77 dCoding["TE_BLRtx"][refName] = blrtxResult
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78
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79 if codingType == "TE_BLRx":
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80 if not dCoding.has_key("TE_BLRx"):
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81 dCoding["TE_BLRx"] = OrderedDict()
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82 for refNameAndCoverage in codingTypeData:
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83 blrxResult = OrderedDict()
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84 refName, coverage = refNameAndCoverage.rsplit(": ", 1)
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85 coverage = float(coverage.replace("%", ""))
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86 blrxResult["cov"] = coverage
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87 dCoding["TE_BLRx"][refName] = blrxResult
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88
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89 if codingType == "profiles":
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90 dCoding["profiles"] = ClassifUtils._formatProfilesResultsAsDict(codingTypeData)
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91
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92 if codingType == "Other_profiles":
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93 dCoding["Other_profiles"] = ClassifUtils._formatProfilesResultsAsDict(codingTypeData)
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94
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95 if codingType == "rDNA_BLRn":
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96 dCoding["rDNA_BLRn"] = OrderedDict()
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97 codingTypeData = ", ".join(codingTypeData)
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98 try:
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99 refName, coverage = codingTypeData.rsplit(": ", 1)
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100 coverage = float(coverage.replace("%", ""))
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101 except ValueError:
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102 refName = codingTypeData
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103 coverage = -1.0
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104
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105 dCoding["rDNA_BLRn"]["name"] = refName
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106 dCoding["rDNA_BLRn"]["cov"] = coverage
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107
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108 if codingType == "HG_BLRn":
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109 dCoding["HG_BLRn"] = OrderedDict()
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110 refName, coverage = codingTypeData[0].rsplit(": ", 1)
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111 coverage = float(coverage.replace("%", ""))
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112
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113 dCoding["HG_BLRn"]["name"] = refName
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114 dCoding["HG_BLRn"]["cov"] = coverage
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115
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116 @staticmethod
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117 def _formatStructFeaturesAsDict(lineOfEvidence, dStruct):
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118 structEvidences = lineOfEvidence.split("; ")
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119 for structTypeData in structEvidences:
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120
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121 structTypeData = structTypeData.split(": ")
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122 structType = structTypeData.pop(0)
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123
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124 structTypeData = ": ".join(structTypeData)
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125 structTypeData = structTypeData.split(", ")
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126
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127 if structType == "TElength":
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128 dStruct["TElength"] = structTypeData.pop()
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129
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130 if structType == "TermRepeats":
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131 dStruct["TermRepeats"] = OrderedDict()
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132 for refNameAndLength in structTypeData:
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133 refName, length = refNameAndLength.rsplit(": ", 1)
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134 dStruct["TermRepeats"][refName] = int(length)
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135
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136 if structType == "ORF":
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137 if not dStruct.has_key("ORF"):
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138 dStruct["ORF"] = structTypeData
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139
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140 if structType in ["SSR", "SSRtrf"]:
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141 if not dStruct.has_key(structType):
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142 dStruct[structType] = structTypeData
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143
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144 if "SSRCoverage" in structType :
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145 dummy, cov = structType.split("=")
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146 dStruct["SSRCoverage"] = float(cov)
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147
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148 if structType == "polyAtail":
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149 dStruct["polyAtail"] = True
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150
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151 if structType == "helitronExtremities":
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152 structTypeData = ", ".join(structTypeData)
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153 structTypeData = structTypeData.split("), ")
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154 dStruct["helitronExtremities"] = OrderedDict()
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155 for helitronData in structTypeData:
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156 helName, helData = helitronData.split(": (")
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157 helData = helData.replace(")", "")
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158 eValue, start, end = helData.split(", ")
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159
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160 helitronExtResult = OrderedDict()
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161 helitronExtResult["start"] = int(start)
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162 helitronExtResult["end"] = int(end)
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163 helitronExtResult["eValue"] = float(eValue)
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164 dStruct["helitronExtremities"][helName] = helitronExtResult
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165
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166 @staticmethod
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167 def _formatOtherFeaturesAsDict(lineOfEvidence, dOther):
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168 if lineOfEvidence != "":
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169 ClassifUtils._formatCodingFeaturesAsDict(lineOfEvidence, dOther)
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170 ClassifUtils._formatStructFeaturesAsDict(lineOfEvidence, dOther)
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171
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172 @staticmethod
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173 def getClassifLineAsDict(line):
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174 dClassif = OrderedDict()
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175 iRenameHeaderClassif = RenameHeaderClassif()
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176 lClassifItem = line.split("\t")
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177 if len(lClassifItem) != 8:
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178 msg = "Can't parse line: \"%s\"\n" % line.strip()
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179 print("WARNING - ClassifUtils - %s" % msg)
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180 return dClassif
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181
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182 teClass = lClassifItem[4]
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183 teOrder = lClassifItem[5]
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184 # TODO: recompute wicker code like this or force the user to provide a classif file as input with the wicker code already added
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185 wCode = iRenameHeaderClassif._decisionRuleForWickerCode(teClass, teOrder)
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186
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187 dClassif["name"] = lClassifItem[0]
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188 dClassif["wCode"] = wCode
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189 dClassif["length"] = int(lClassifItem[1])
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190 dClassif["strand"] = lClassifItem[2]
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191 dClassif["chimeric"] = False if lClassifItem[3] == "ok" else True
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192
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193 dClassif["class"] = teClass
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194 dClassif["order"] = teOrder
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195
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196 if(lClassifItem[6] == "complete"):
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197 dClassif["complete"] = True
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198 elif(lClassifItem[6] == "incomplete"):
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199 dClassif["complete"] = False
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200 else:
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201 dClassif["complete"] = None
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202
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203 allFields = lClassifItem[7].split("; ")
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204
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205 CI = allFields.pop(0)
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206 CI = CI.split("=")[-1]
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207 if CI != "NA":
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208 try:
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209 CI = int(CI)
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210 except ValueError as e:
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211 print "Couldn't convert %s to int : %s" % (CI, e)
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212 dClassif["CI"] = CI
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213
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214 dClassif["coding"] = OrderedDict()
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215 dClassif["struct"] = OrderedDict()
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216 dClassif["other"] = OrderedDict()
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217
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218 allFields = "; ".join(allFields)
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219 codingField = ""
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220 structField = ""
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221 otherField = ""
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222
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223 codingStart = allFields.find("coding=(")
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224 if codingStart != -1:
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225 pCount = 1
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226 trueStart = codingStart + len("coding=(")
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227 end = trueStart
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228 for char in allFields[trueStart:]:
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229 if char == "(":
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230 pCount += 1
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231 if char == ")":
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232 pCount -= 1
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233 if pCount == 0:
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234 break;
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235 end += 1
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236 if pCount == 0:
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237 codingField = allFields[trueStart:end]
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238
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239 structStart = allFields.find("struct=(")
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240 if structStart != -1:
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241 pCount = 1
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242 trueStart = structStart + len("struct=(")
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243 end = trueStart
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244 for char in allFields[trueStart:]:
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245 if char == "(":
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246 pCount += 1
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247 if char == ")":
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248 pCount -= 1
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249 if pCount == 0:
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250 break;
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251 end += 1
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252 structField = allFields[trueStart:end]
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253
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254 otherStart = allFields.find("other=(")
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255 if otherStart != -1:
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256 pCount = 1
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257 trueStart = otherStart + len("other=(")
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258 end = trueStart
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259 for char in allFields[trueStart:]:
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260 if char == "(":
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261 pCount += 1
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262 if char == ")":
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263 pCount -= 1
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264 if pCount == 0:
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265 break;
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266 end += 1
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267 otherField = allFields[trueStart:end]
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268
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269 if codingField != "":
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270 ClassifUtils._formatCodingFeaturesAsDict(codingField, dClassif["coding"])
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271 if structField != "":
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272 ClassifUtils._formatStructFeaturesAsDict(structField, dClassif["struct"])
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273 if otherField != "":
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274 ClassifUtils._formatOtherFeaturesAsDict(otherField, dClassif["other"])
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275
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276 return dClassif
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277
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278 ## Retrieve the classification informations of a classif file
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279 #
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280 # @param fileName Name of the classif file
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281 # @return A dict containing the classification infos
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282 #
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283 @staticmethod
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284 def getClassifInfosAsDict(fileName):
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285 dConsensusInfo = OrderedDict()
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286
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287 ext = os.path.splitext(fileName)[1]
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288 if ext != ".classif":
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289 msg = "Input file must be a classif file from TEdenovo\n"
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290 print("ERROR - ClassifUtils - %s" % msg)
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291 exit(1)
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292
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293 with open(fileName, "r") as classifFile:
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294 for line in classifFile:
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295 seqName = line.split("\t")[0]
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296 dConsensusInfo[seqName] = ClassifUtils.getClassifLineAsDict(line)
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297
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298 return dConsensusInfo
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299
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300 ## Convert a classif file to JSON format
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301 #
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302 # @param fileName Name of the classif file
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303 # @param outFileName Name of the output JSON file (optional)
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304 #
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305 @staticmethod
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306 def convertClassifToJson(fileName, outFileName = ""):
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307 dConsensusInfo = ClassifUtils.getClassifInfosAsDict(fileName)
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308 if outFileName == "":
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309 outFileName = "%s_classif.json" % (os.path.basename(fileName).rsplit(".", 1)[0])
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310 with open(outFileName, 'w') as outFile:
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311 json.dump(dConsensusInfo, outFile)
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