13
|
1 # Copyright INRA (Institut National de la Recherche Agronomique)
|
|
2 # http://www.inra.fr
|
|
3 # http://urgi.versailles.inra.fr
|
|
4 #
|
|
5 # This software is governed by the CeCILL license under French law and
|
|
6 # abiding by the rules of distribution of free software. You can use,
|
|
7 # modify and/ or redistribute the software under the terms of the CeCILL
|
|
8 # license as circulated by CEA, CNRS and INRIA at the following URL
|
|
9 # "http://www.cecill.info".
|
|
10 #
|
|
11 # As a counterpart to the access to the source code and rights to copy,
|
|
12 # modify and redistribute granted by the license, users are provided only
|
|
13 # with a limited warranty and the software's author, the holder of the
|
|
14 # economic rights, and the successive licensors have only limited
|
|
15 # liability.
|
|
16 #
|
|
17 # In this respect, the user's attention is drawn to the risks associated
|
|
18 # with loading, using, modifying and/or developing or reproducing the
|
|
19 # software by the user in light of its specific status of free software,
|
|
20 # that may mean that it is complicated to manipulate, and that also
|
|
21 # therefore means that it is reserved for developers and experienced
|
|
22 # professionals having in-depth computer knowledge. Users are therefore
|
|
23 # encouraged to load and test the software's suitability as regards their
|
|
24 # requirements in conditions enabling the security of their systems and/or
|
|
25 # data to be ensured and, more generally, to use and operate it in the
|
|
26 # same conditions as regards security.
|
|
27 #
|
|
28 # The fact that you are presently reading this means that you have had
|
|
29 # knowledge of the CeCILL license and that you accept its terms.
|
|
30
|
|
31
|
|
32 import sys
|
|
33 from commons.core.coord.Range import Range
|
|
34 from commons.core.coord.Path import Path
|
|
35
|
|
36
|
|
37 ## Handle a chain of match(es) between two sequences, query and subject, with an identifier and the length of the input sequences
|
|
38 #
|
|
39 class Match( Path ):
|
|
40
|
|
41 __slots__ = ("query_length", "query_length_perc", "query_seqlength", "match_length_perc", "subject_length", "subject_length_perc", "subject_seqlength")
|
|
42
|
|
43 ## Constructor
|
|
44 #
|
|
45 def __init__(self):
|
|
46 Path.__init__(self)
|
|
47 self.query_length = -1
|
|
48 self.query_length_perc = -1 # length of the match on the query / length of the query
|
|
49 self.query_seqlength = -1
|
|
50 self.match_length_perc = -1 # length of the match on the query / total length of the subject
|
|
51 self.subject_length = -1
|
|
52 self.subject_length_perc = -1 # length of the match on the subject / length of the subject
|
|
53 self.subject_seqlength = -1
|
|
54
|
|
55 ## Equal operator
|
|
56 #
|
|
57 def __eq__(self, o):
|
|
58 if type(o) is not type(self)\
|
|
59 or self.query_length != o.query_length or self.query_length_perc != o.query_length_perc\
|
|
60 or self.query_seqlength != o.query_seqlength or self.subject_length != o.subject_length\
|
|
61 or self.subject_length_perc != o.subject_length_perc or self.subject_seqlength != o.subject_seqlength\
|
|
62 or self.match_length_perc != o.match_length_perc:
|
|
63 return False
|
|
64 return Path.__eq__(self, o)
|
|
65
|
|
66 ## Not equal operator
|
|
67 #
|
|
68 def __ne__(self, o):
|
|
69 return not self.__eq__(o)
|
|
70
|
|
71 ## Return the length of the match on the query divided by the total length of the query
|
|
72 #
|
|
73 def getLengthPercOnQuery(self):
|
|
74 return self.query_length_perc
|
|
75
|
|
76 ## Return the length of the match on the subject divided by the total length of the subject
|
|
77 #
|
|
78 def getLengthPercOnSubject(self):
|
|
79 return self.subject_length_perc
|
|
80
|
|
81 ## Return the length of the match on the subject
|
|
82 #
|
|
83 def getLengthMatchOnSubject(self):
|
|
84 return self.subject_length
|
|
85
|
|
86 ## Set attributes from a tuple
|
|
87 #
|
|
88 # @param tuple: a tuple with (query name,query start,query end,
|
|
89 # query length, query length perc (between 0-1), match length perc (between 0-1), subject name,
|
|
90 # subject start,subject end,subject length, subject length percentage (between 0-1), e_value,score,identity,id)
|
|
91 #
|
|
92 def setFromTuple( self, tuple ):
|
|
93 queryStart = int(tuple[1])
|
|
94 queryEnd = int(tuple[2])
|
|
95 subjectStart = int(tuple[7])
|
|
96 subjectEnd = int(tuple[8])
|
|
97 if queryStart < queryEnd:
|
|
98 self.range_query = Range(tuple[0],queryStart,queryEnd)
|
|
99 self.range_subject = Range(tuple[6],subjectStart,subjectEnd)
|
|
100 else:
|
|
101 self.range_query = Range(tuple[0],queryEnd,queryStart)
|
|
102 self.range_subject = Range(tuple[6],subjectEnd,subjectStart)
|
|
103 self.query_length = int(tuple[3])
|
|
104 self.query_length_perc = float(tuple[4])
|
|
105 self.query_seqlength = int( self.query_length / self.query_length_perc )
|
|
106 self.match_length_perc = float(tuple[5])
|
|
107 self.subject_length = int(tuple[9])
|
|
108 self.subject_length_perc = float(tuple[10])
|
|
109 self.subject_seqlength = int( self.subject_length / self.subject_length_perc )
|
|
110 self.e_value = float(tuple[11])
|
|
111 self.score = float(tuple[12])
|
|
112 self.identity = float(tuple[13])
|
|
113 self.id = int(tuple[14])
|
|
114
|
|
115 ## Reset
|
|
116 #
|
|
117 def reset( self ):
|
|
118 Path.reset( self )
|
|
119 self.query_length = -1
|
|
120 self.query_length_perc = -1
|
|
121 self.query_seqlength = -1
|
|
122 self.match_length_perc = -1
|
|
123 self.subject_length = -1
|
|
124 self.subject_length_perc = -1
|
|
125 self.subject_seqlength = -1
|
|
126
|
|
127 ## Return a formated string of the attribute data
|
|
128 #
|
|
129 def toString( self ):
|
|
130 string = "%s" % ( self.range_query.toString() )
|
|
131 string += "\t%i\t%f" % ( self.query_length,
|
|
132 self.query_length_perc )
|
|
133 string += "\t%f" % ( self.match_length_perc )
|
|
134 string += "\t%s" % ( self.range_subject.toString() )
|
|
135 string += "\t%i\t%f" % ( self.subject_length,
|
|
136 self.subject_length_perc )
|
|
137 string += "\t%g\t%i\t%f" % ( self.e_value,
|
|
138 self.score,
|
|
139 self.identity )
|
|
140 string += "\t%i" % ( self.id )
|
|
141 return string
|
|
142
|
|
143 ## Return a Path instance
|
|
144 #
|
|
145 def getPathInstance( self ):
|
|
146 p = Path()
|
|
147 tuple = ( self.id,
|
|
148 self.range_query.seqname,
|
|
149 self.range_query.start,
|
|
150 self.range_query.end,
|
|
151 self.range_subject.seqname,
|
|
152 self.range_subject.start,
|
|
153 self.range_subject.end,
|
|
154 self.e_value,
|
|
155 self.score,
|
|
156 self.identity )
|
|
157 p.setFromTuple( tuple )
|
|
158 return p
|
|
159
|
|
160 ## Give information about a match whose query is included in the subject
|
|
161 #
|
|
162 # @return string
|
|
163 #
|
|
164 def getQryIsIncluded( self ):
|
|
165 string = "query %s (%d bp: %d-%d) is contained in subject %s (%d bp: %d-%d): id=%.2f - %.3f - %.3f - %.3f" %\
|
|
166 ( self.range_query.seqname, self.query_seqlength, self.range_query.start, self.range_query.end,
|
|
167 self.range_subject.seqname, self.subject_seqlength, self.range_subject.start, self.range_subject.end,
|
|
168 self.identity, self.query_length_perc, self.match_length_perc, self.subject_length_perc )
|
|
169 return string
|
|
170
|
|
171 def increaseLengthPercOnQuery(self, coverage):
|
|
172 self.query_length_perc += coverage
|
|
173
|
|
174 ## Compare the object with another match and see if they are equal
|
|
175 # (same identity, E-value and score + same subsequences whether in query or subject)
|
|
176 #
|
|
177 # @return True if objects are equals False otherwise
|
|
178 #
|
|
179 def isDoublonWith( self, match, verbose=0 ):
|
|
180
|
|
181 # if both matches have same identity, score and E-value
|
|
182 if self.identity == match.identity and self.score == match.score and self.e_value == match.e_value:
|
|
183
|
|
184 # if query and subject are identical
|
|
185 if ( self.range_query.seqname == match.range_query.seqname \
|
|
186 and self.range_subject.seqname == match.range_subject.seqname ):
|
|
187
|
|
188 # if the coordinates are equal
|
|
189 if self.range_query.__eq__( match.range_query ) and self.range_subject.__eq__( match.range_subject ):
|
|
190 return True
|
|
191
|
|
192 else:
|
|
193 if verbose > 0: print "different coordinates"; sys.stdout.flush()
|
|
194 return False
|
|
195
|
|
196 # if query and subject are reversed but identical
|
|
197 elif self.range_query.seqname == match.range_subject.seqname and self.range_subject.seqname == match.range_query.seqname:
|
|
198
|
|
199 # if the coordinates are equal
|
|
200 if self.range_query.__eq__( match.range_subject ) and self.range_subject.__eq__( match.range_query ):
|
|
201 return True
|
|
202
|
|
203 else:
|
|
204 if verbose > 0: print "different coordinates"; sys.stdout.flush()
|
|
205 return False
|
|
206
|
|
207 else:
|
|
208 if verbose > 0: print "different sequence names"; sys.stdout.flush()
|
|
209 return False
|
|
210
|
|
211 else:
|
|
212 if verbose > 0: print "different match numbers"; sys.stdout.flush()
|
|
213 return False
|