Mercurial > repos > yufei-luo > s_mart
annotate smart_toolShed/commons/core/parsing/GffParser.py @ 0:e0f8dcca02ed
Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
author | yufei-luo |
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date | Thu, 17 Jan 2013 10:52:14 -0500 |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
yufei-luo
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1 # |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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2 # Copyright INRA-URGI 2009-2010 |
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3 # |
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4 # This software is governed by the CeCILL license under French law and |
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5 # abiding by the rules of distribution of free software. You can use, |
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6 # modify and/ or redistribute the software under the terms of the CeCILL |
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7 # license as circulated by CEA, CNRS and INRIA at the following URL |
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8 # "http://www.cecill.info". |
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9 # |
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10 # As a counterpart to the access to the source code and rights to copy, |
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11 # modify and redistribute granted by the license, users are provided only |
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12 # with a limited warranty and the software's author, the holder of the |
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13 # economic rights, and the successive licensors have only limited |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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14 # liability. |
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15 # |
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16 # In this respect, the user's attention is drawn to the risks associated |
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17 # with loading, using, modifying and/or developing or reproducing the |
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18 # software by the user in light of its specific status of free software, |
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19 # that may mean that it is complicated to manipulate, and that also |
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20 # therefore means that it is reserved for developers and experienced |
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21 # professionals having in-depth computer knowledge. Users are therefore |
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22 # encouraged to load and test the software's suitability as regards their |
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23 # requirements in conditions enabling the security of their systems and/or |
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24 # data to be ensured and, more generally, to use and operate it in the |
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25 # same conditions as regards security. |
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26 # |
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27 # The fact that you are presently reading this means that you have had |
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28 # knowledge of the CeCILL license and that you accept its terms. |
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29 # |
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30 import re |
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31 import sys |
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32 from SMART.Java.Python.structure.Interval import Interval |
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33 from SMART.Java.Python.structure.Transcript import Transcript |
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34 from commons.core.parsing.TranscriptListParser import TranscriptListParser |
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35 |
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36 |
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37 class GffParser(TranscriptListParser): |
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38 """A class that parses a GFF file and create a transcript list""" |
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39 |
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40 |
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41 def __init__(self, fileName, verbosity = 0): |
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42 super(GffParser, self).__init__(fileName, verbosity) |
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43 |
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44 |
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45 def __del__(self): |
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46 super(GffParser, self).__del__() |
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47 |
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48 |
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49 def getFileFormats(): |
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50 return ["gff", "gff2", "gff3"] |
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51 getFileFormats = staticmethod(getFileFormats) |
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52 |
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53 |
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54 def skipFirstLines(self): |
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55 pass |
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56 |
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57 |
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58 def getInfos(self): |
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59 self.chromosomes = set() |
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60 self.nbTranscripts = 0 |
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61 self.size = 0 |
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62 self.reset() |
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63 if self.verbosity >= 10: |
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64 print "Getting information on %s." % (self.fileName) |
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65 self.reset() |
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66 for line in self.handle: |
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67 line = line.strip() |
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68 if line == "" or line[0] == "#": |
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69 continue |
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70 parts = line.split("\t") |
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71 if len(parts) != 9: |
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72 raise Exception("Error! Line '%s' has %d tab-separated fields instead of 9!" % (line, len(parts))) |
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73 self.chromosomes.add(parts[0]) |
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74 if parts[8].find("Parent") == -1: |
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75 self.nbTranscripts += 1 |
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76 else: |
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77 self.size += max(int(parts[3]), int(parts[4])) - min(int(parts[3]), int(parts[4])) + 1 |
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78 if self.verbosity >= 10 and self.nbTranscripts % 100000 == 0: |
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79 sys.stdout.write(" %d transcripts read\r" % (self.nbTranscripts)) |
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80 sys.stdout.flush() |
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81 self.reset() |
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82 if self.verbosity >= 10: |
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83 print " %d transcripts read" % (self.nbTranscripts) |
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84 print "Done." |
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85 |
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86 |
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87 def parseLine(self, line): |
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88 if not line or line[0] == "#": |
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89 return None |
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90 m = re.search(r"^\s*(\S+)\s+(\S+)\s+(\S+)\s+(\d+)\s+(\d+)\s+(\S+)\s+([+-.])\s+(\S+)\s+(\S.*)$", line) |
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91 if m == None: |
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92 raise Exception("\nLine %d '%s' does not have a GFF format\n" % (self.currentLineNb, line)) |
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93 interval = Interval() |
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94 interval.setChromosome(m.group(1)) |
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95 interval.setName("unnamed transcript") |
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96 interval.setStart(min(int(m.group(4)), int(m.group(5)))) |
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97 interval.setEnd(max(int(m.group(4)), int(m.group(5)))) |
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98 if m.group(7) == ".": |
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99 interval.setDirection("+") |
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100 else: |
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101 interval.setDirection(m.group(7)) |
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102 interval.setTagValue("feature", m.group(3)) |
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103 if m.group(6).isdigit(): |
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104 interval.setTagValue("score", m.group(6)) |
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105 |
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106 remainings = m.group(9).split(";") |
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107 for remaining in remainings: |
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108 remaining = remaining.strip() |
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109 if remaining == "": |
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110 continue |
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111 posSpace = remaining.find(" ") |
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112 posEqual = remaining.find("=") |
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113 if posEqual != -1 and (posEqual < posSpace or posSpace == -1): |
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114 parts = remaining.split("=") |
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115 else: |
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116 parts = remaining.split() |
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117 field = parts[0].strip() |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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118 value = " ".join(parts[1:]).strip(" \"") |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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119 if field in ("Name", "name", "Sequence", "TE", "SAT"): |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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120 interval.setName(value) |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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121 else: |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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122 try: |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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123 intValue = int(value) |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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124 interval.setTagValue(field, intValue) |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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125 except ValueError: |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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126 interval.setTagValue(field, value) |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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127 |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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128 self.currentTranscriptAddress = self.previousTranscriptAddress |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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129 if "Parent" in interval.getTagNames(): |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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130 if self.currentTranscript == None: |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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131 raise Exception("GFF file does not start with a transcript! First line is '%s'." % (line.strip())) |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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132 if interval.getTagValue("Parent") != self.currentTranscript.getTagValue("ID"): |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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133 raise Exception("Exon '%s' is not right after its transcript in GFF file!" % (interval)) |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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134 self.currentTranscript.addExon(interval) |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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135 if interval.name == None: |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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136 interval.name = self.currentTranscript.name |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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137 return None |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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138 |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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139 transcript = self.currentTranscript |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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140 self.currentTranscript = Transcript() |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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141 self.currentTranscript.copy(interval) |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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142 self.previousTranscriptAddress = self.currentAddress |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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143 |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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144 if transcript != None and transcript.name.startswith("unnamed"): |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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145 if "ID" in transcript.getTagNames(): |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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146 transcript.name = transcript.getTagValue("ID") |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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147 else: |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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148 transcript.name = "unnamed transcript %s" % (self.currentLineNb) |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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149 return transcript |