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1 #Gene_ID Gene_name Codon_pos Ref_nuc Ref_codon Res_codon Resistance PMID Mechanism Notes Required_mut
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2 gyrA gyrA 70 GCC A T Nalidixic acid, Ciprofloxacin 8384814 Target modification
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3 gyrA gyrA 85 GAT D Y Nalidixic acid, Ciprofloxacin 18031331 Target modification Phenotype described only in association with other mutations (T86), unknown phenotype if the present mutation occurs alone gyrA_T86I.A.K.V
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4 gyrA gyrA 86 ACA T I,A,K,V Nalidixic acid, Ciprofloxacin 11266291,Unpublished,8384814,16713726 Target modification
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5 gyrA gyrA 90 GAT D A,N,T Nalidixic acid, Ciprofloxacin 8384814,8384814,16713726 Target modification
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6 gyrA gyrA 104 CCA P S Nalidixic acid, Ciprofloxacin 16713726 Target modification Phenotype described only in association with other mutations (R285), unknown phenotype if the present mutation occurs alone gyrA_R285K
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7 23S 23S 2074 A A G,T,C Azithromycin, Erythromycin, Clindamycin, Telithromycin 16713726,16713726,16713726 Target modification
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8 23S 23S 2075 A A G Azithromycin, Erythromycin, Clindamycin, Telithromycin 16713726 Target modification
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9 rpsL rpsL 43 AAA K R Streptomycin 20370506 Target modification
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10 rpsL rpsL 88 AAA K R,E,Q Streptomycin 20370506 Target modification |
