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comparison test-data/model/SPIKE_SARS2.hhr @ 0:c3e9ffb4c98a draft

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"planemo upload commit 6158473dbced09024b0a805a7df2c93d47705d87"
author guerler
date Tue, 23 Mar 2021 13:56:55 +0000
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-1:000000000000 0:c3e9ffb4c98a
1 Query sp|P0DTC2|SPIKE_SARS2 Spike glycoprotein OS=Severe acute respiratory syndrome coronavirus 2 OX=2697049 GN=S PE=1 SV=1
2 Match_columns 1273
3 No_of_seqs 1 out of 1
4 Neff 1
5 Searched_HMMs 82491
6 Date Thu Nov 12 20:44:30 2020
7 Command hhsearch -e 0.001 -i /galaxy-repl/main/files/047/416/dataset_47416633.dat -d hhdb -o /galaxy-repl/main/files/047/416/dataset_47416669.dat
8
9 No Hit Prob E-value P-value Score SS Cols Query HMM Template HMM
10 1 6X29_A Spike glycoprotein; Tri 100.0 3E-269 4E-274 2251.1 0.0 1198 16-1213 1-1198(1273)
11 2 6CS2_B Spike glycoprotein,Enve 100.0 3E-221 4E-226 1857.5 0.0 1161 31-1213 22-1182(1215)
12 3 6Q04_B Spike glycoprotein; Cor 100.0 2E-204 2E-209 1723.9 0.0 1150 31-1224 65-1321(1359)
13 4 5I08_C Spike glycoprotein; cor 100.0 2E-199 2E-204 1685.1 0.0 1142 30-1223 29-1293(1299)
14 5 5X5F_B S protein; MERS-CoV, sp 100.0 6E-198 7E-203 1670.1 0.0 1163 14-1220 12-1286(1323)
15 6 6VSJ_A Spike glycoprotein, Car 100.0 2E-195 3E-200 1649.5 0.0 1145 9-1204 22-1267(1275)
16 7 6VSJ_C Spike glycoprotein, Car 100.0 2E-195 3E-200 1649.5 0.0 1145 9-1204 22-1267(1275)
17 8 6OHW_A Spike surface glycoprot 100.0 7E-190 9E-195 1602.1 0.0 1144 2-1204 13-1299(1322)
18 9 6NZK_A Spike surface glycoprot 100.0 7E-190 9E-195 1602.1 0.0 1144 2-1204 13-1299(1322)
19 10 6M15_A Spike glycoprotein; VIR 100.0 6E-154 7E-159 1294.0 0.0 832 273-1215 216-1070(1118)
20 11 6M15_B Spike glycoprotein; VIR 100.0 6E-154 7E-159 1294.0 0.0 832 273-1215 216-1070(1118)
21 12 6JX7_A Feline Infectious Perit 100.0 2E-132 2E-137 1149.2 0.0 664 525-1216 674-1394(1468)
22 13 5SZS_A Spike glycoprotein; cor 100.0 7E-131 9E-136 1128.9 0.0 662 505-1215 575-1283(1325)
23 14 6IXB_B Spike glycoprotein; Alp 100.0 8E-129 1E-133 1101.7 0.0 647 518-1214 426-1116(1116)
24 15 6CV0_A Spike protein; infectio 100.0 3E-125 3E-130 1068.9 0.0 651 524-1212 399-1074(1105)
25 16 6VV5_C Spike glycoprotein; gly 100.0 2E-124 2E-129 1078.6 0.0 641 521-1213 614-1309(1356)
26 17 6M3W_B Spike glycoprotein,Spik 100.0 2E-124 2E-129 1000.4 0.0 491 706-1196 1-491 (491)
27 18 6U7K_C Spike glycoprotein; PED 100.0 1E-122 1E-127 1065.5 0.0 641 521-1213 629-1324(1399)
28 19 6BFU_C Spike protein; coronavi 100.0 4E-119 4E-124 1017.5 0.0 746 267-1148 240-1022(1024)
29 20 6B3O_B Spike glycoprotein; Cor 100.0 7E-117 9E-122 954.9 0.0 497 703-1203 45-560 (605)
30 21 6PZ8_A S protein, G2 heavy cha 100.0 8E-112 1E-116 897.4 0.0 445 694-1140 12-470 (472)
31 22 6PZ8_F S protein, G2 heavy cha 100.0 3.1E-74 3.8E-79 636.3 0.0 621 14-676 12-724 (726)
32 23 7BZ5_A Spike protein S1, Heavy 100.0 3.5E-52 4.2E-57 416.5 0.0 225 319-543 1-225 (229)
33 24 6YZ5_E Spike glycoprotein, Nan 100.0 3.5E-51 4.3E-56 405.6 0.0 205 330-534 1-205 (210)
34 25 6YLA_E SARS-CoV-2 RBD, Heavy C 100.0 3.8E-51 4.6E-56 406.0 0.0 207 328-534 2-208 (213)
35 26 6ZFO_A SARS-CoV-2 RBD, Nanobod 100.0 2.3E-47 2.8E-52 375.2 0.0 194 333-526 1-194 (194)
36 27 2GHV_C Spike glycoprotein; SAR 100.0 3.9E-37 4.7E-42 305.0 0.0 197 330-527 4-200 (203)
37 28 1WYY_A E2 Glycoprotein; membra 100.0 2.3E-36 2.8E-41 288.5 0.0 99 903-1001 3-101 (149)
38 29 1WYY_B E2 Glycoprotein; membra 100.0 2.3E-36 2.8E-41 288.5 0.0 99 903-1001 3-101 (149)
39 30 5X4S_A Spike glycoprotein; SAR 100.0 1.1E-34 1.4E-39 298.0 0.0 261 30-307 21-281 (285)
40 31 5KWB_A Spike glycoprotein; Cor 100.0 1.2E-33 1.4E-38 297.9 0.0 271 316-592 1-370 (371)
41 32 6LXT_F Spike protein S2; 2019- 99.9 2.8E-28 3.4E-33 230.5 0.0 112 910-1021 1-113 (132)
42 33 6LXT_C 2019-nCoV S2 subunit; 2 99.9 2.8E-28 3.4E-33 230.5 0.0 112 910-1021 1-113 (132)
43 34 6C6Z_A Spike protein, CDC2-C2 99.9 6.9E-26 8.3E-31 228.8 0.0 148 319-472 1-148 (231)
44 35 5XGR_H Spike protein S1; MERS- 99.8 9.7E-26 1.2E-30 224.7 0.0 181 335-528 2-198 (204)
45 36 4QZV_B Dipeptidyl peptidase 4 99.8 4.1E-25 5E-30 224.7 0.0 137 319-458 1-139 (246)
46 37 4L3N_B S protein; beta-sheet f 99.8 2.3E-24 2.8E-29 216.3 0.0 124 334-458 3-126 (216)
47 38 5YY5_B MERS-CoV RBD, Heavy cha 99.8 3.5E-24 4.2E-29 214.4 0.0 124 334-458 2-125 (209)
48 39 4L72_B Dipeptidyl peptidase 4 99.8 4E-24 4.8E-29 213.4 0.0 123 335-458 1-123 (204)
49 40 3R4D_D CEA-related cell adhesi 99.8 5.2E-24 6.3E-29 219.9 0.0 240 30-304 30-283 (288)
50 41 4NJL_A S protein; six-helix-bu 99.8 1.2E-23 1.4E-28 199.4 0.0 122 910-1035 2-125 (131)
51 42 6QFY_A Spike glycoprotein; sia 99.8 2.6E-23 3.2E-28 214.7 0.0 236 30-305 29-286 (288)
52 43 4H14_A Spike glycoprotein; bet 99.8 3.5E-23 4.3E-28 214.0 0.0 235 30-304 29-285 (290)
53 44 4MOD_B HR1 of S protein, LINKE 99.8 1.9E-22 2.2E-27 191.3 0.0 118 918-1039 2-121 (129)
54 45 5X4R_A S protein; MERS-CoV, sp 99.7 2.2E-21 2.7E-26 204.5 0.0 263 14-306 12-337 (342)
55 46 6J11_C Spike glycoprotein, VH 99.7 2.8E-21 3.3E-26 203.4 0.0 262 14-305 12-336 (336)
56 47 5GYQ_A Spike glycoprotein; bat 99.7 4.2E-21 5E-26 188.9 0.0 108 332-440 2-109 (176)
57 48 5ZVK_A Human Coronavirus MERS 99.7 7.3E-21 8.9E-26 169.6 0.0 79 910-988 2-80 (80)
58 49 2BEZ_C E2 GLYCOPROTEIN; MEMBRA 99.6 8.5E-20 1E-24 162.0 0.0 77 914-990 1-77 (77)
59 50 6M1V_A spike protein; 2019-nCo 99.6 2.8E-19 3.4E-24 168.2 0.0 98 917-1020 1-98 (119)
60 51 5ZUV_A Spike glycoprotein,EK1, 99.6 1.2E-18 1.5E-23 166.1 0.0 83 914-996 2-98 (133)
61 52 5YL9_A Spike glycoprotein; Spi 99.5 1.1E-17 1.3E-22 151.9 0.0 74 914-987 2-89 (89)
62 53 1WDF_B E2 glycoprotein; MHV, c 99.2 2.7E-14 3.2E-19 131.3 0.0 62 919-980 1-62 (95)
63 54 1ZVA_A E2 glycoprotein; SARS c 99.0 1.7E-13 2.1E-18 121.9 0.0 58 1144-1201 15-77 (77)
64 55 5ZHY_D Spike glycoprotein,Spik 98.8 7.4E-12 9E-17 122.0 0.0 59 918-976 1-73 (148)
65 56 5XJK_A Spike protein S2; VIRAL 98.7 1.4E-11 1.7E-16 107.0 0.0 62 777-838 3-64 (65)
66 57 1ZV8_K E2 glycoprotein; SARS c 98.6 1.2E-10 1.4E-15 98.3 0.0 50 919-968 1-50 (50)
67 58 2IEQ_B Spike glycoprotein; Hum 98.5 1.3E-10 1.5E-15 109.6 0.0 84 921-1005 7-99 (109)
68 59 2FXP_A Spike glycoprotein; Pre 98.5 1.6E-10 2E-15 98.2 0.0 54 1158-1211 2-55 (55)
69 60 1WDG_B E2 glycoprotein; MHV, c 98.5 2.2E-10 2.6E-15 106.1 0.0 54 919-972 1-56 (94)
70 61 2BEQ_D E2 GLYCOPROTEIN; VIRAL 98.4 5.2E-10 6.3E-15 93.7 0.0 47 1166-1212 2-48 (48)
71 62 2BEQ_E E2 GLYCOPROTEIN; VIRAL 98.4 5.2E-10 6.3E-15 93.7 0.0 47 1166-1212 2-48 (48)
72 63 6LXT_F Spike protein S2; 2019- 97.7 1.4E-07 1.7E-12 91.8 0.0 45 1163-1207 87-131 (132)
73 64 6LXT_C 2019-nCoV S2 subunit; 2 97.7 1.4E-07 1.7E-12 91.8 0.0 45 1163-1207 87-131 (132)
74 65 4MOD_B HR1 of S protein, LINKE 97.5 4.8E-07 5.8E-12 88.0 0.0 64 1142-1205 40-123 (129)
75 66 1ZVB_A E2 glycoprotein; SARS c 97.3 1.9E-06 2.2E-11 69.0 0.0 34 958-991 1-34 (34)
76 67 1WDG_B E2 glycoprotein; MHV, c 97.1 5.1E-06 6.2E-11 77.9 0.0 47 1156-1202 44-94 (94)
77 68 6M1V_A spike protein; 2019-nCo 97.0 8.6E-06 1E-10 78.8 0.0 49 1157-1205 67-115 (119)
78 69 2BEQ_C E2 GLYCOPROTEIN; VIRAL 97.0 9.9E-06 1.2E-10 66.1 0.0 36 932-967 2-37 (38)
79 70 5ZVM_c Human Coronavirus SARS 96.7 2.6E-05 3.2E-10 65.3 0.0 41 1165-1205 4-44 (44)
80 71 5ZVM_b Human Coronavirus SARS 96.7 2.6E-05 3.2E-10 65.3 0.0 41 1165-1205 4-44 (44)
81 72 2BEZ_F E2 GLYCOPROTEIN; MEMBRA 96.4 8.7E-05 1.1E-09 61.4 0.0 42 1160-1201 1-42 (42)
82 73 6LVN_B 2019-nCoV S2 subunit; 2 96.2 0.00019 2.3E-09 58.1 0.0 35 1169-1203 2-36 (36)
83 74 1ZV8_B E2 glycoprotein; SARS c 96.2 0.00019 2.3E-09 58.1 0.0 35 1169-1203 2-36 (36)
84 75 6LVN_A Spike protein S2; 2019- 96.2 0.00019 2.3E-09 58.1 0.0 35 1169-1203 2-36 (36)
85 76 5YL9_B Spike glycoprotein; Spi 91.7 0.063 7.7E-07 48.0 0.0 41 1158-1201 4-58 (59)
86 77 5ZUV_A Spike glycoprotein,EK1, 89.5 0.16 2E-06 51.2 0.0 44 1161-1204 90-133 (133)
87 78 6MAR_D Immunoglobulin G PGT151 71.2 3 3.7E-05 42.9 0.0 29 1199-1227 154-183 (220)
88 79 6DCQ_D Envelope glycoprotein g 68.2 3.9 4.7E-05 45.1 0.0 49 1197-1245 146-195 (352)
89 80 6NIJ_B PGT145 Fab heavy chain, 68.2 3.9 4.7E-05 44.9 0.0 51 1197-1247 146-197 (345)
90 81 1WDF_B E2 glycoprotein; MHV, c 63.1 5.7 7E-05 39.1 0.0 56 1144-1202 40-95 (95)
91 82 6GY6_C XaxA, XaxB; bacterial t 58.0 8.2 9.9E-05 41.0 0.0 24 1172-1195 232-255 (424)
92 83 6OJ7_A Fusion glycoprotein F0; 57.5 8.5 0.0001 34.2 0.0 29 927-955 17-45 (53)
93 84 1G2C_W TWO HEPTAD REPEATS OF H 57.5 8.5 0.0001 34.1 0.0 29 927-955 17-45 (52)
94 85 6NYX_H Fusion glycoprotein F0; 57.3 8.6 0.0001 34.1 0.0 29 927-955 17-45 (53)
95 86 6O40_A Fusion glycoprotein F0; 57.3 8.6 0.0001 34.1 0.0 29 927-955 17-45 (53)
96 87 6GY8_A XaxA; bacterial toxin, 55.0 10 0.00012 39.7 0.0 22 1173-1194 233-254 (408)
97 88 6PWU_E Envelope glycoprotein g 52.0 12 0.00014 46.6 0.0 53 1196-1248 651-704 (858)
98 89 3EUH_B Chromosome partition pr 52.0 12 0.00014 44.2 0.0 126 858-988 125-264 (440)
99 90 3MAW_A Fusion glycoprotein F0; 50.7 13 0.00016 44.0 0.0 76 875-955 83-158 (483)
100 91 6EK7_A YaxA; pathogens, pore f 49.9 14 0.00017 39.3 0.0 23 1172-1194 234-256 (410)
101 92 1SVF_C SV5 FUSION PROTEIN; PAR 49.4 14 0.00017 34.0 0.0 29 927-955 26-54 (64)
102 93 1SVF_A SV5 FUSION PROTEIN; PAR 49.4 14 0.00017 34.0 0.0 29 927-955 26-54 (64)
103 94 2FYZ_E Fusion glycoprotein F0; 48.5 15 0.00018 33.8 0.0 29 927-955 29-57 (63)
104 95 2B9B_B Parainfluenza Virus 5 F 48.3 15 0.00018 43.7 0.0 76 875-955 79-154 (497)
105 96 5YZC_B glycoprotein F2, glycop 47.2 16 0.00019 42.7 0.0 73 878-955 1-73 (419)
106 97 1T98_B Chromosome partition pr 46.8 16 0.0002 41.3 0.0 104 858-966 125-236 (287)
107 98 1T98_A Chromosome partition pr 46.8 16 0.0002 41.3 0.0 104 858-966 125-236 (287)
108 99 1G5G_F FUSION PROTEIN; fusion 45.6 18 0.00021 42.9 0.0 76 875-955 83-158 (481)
109 100 5EVM_F Fusion glycoprotein F0; 45.4 18 0.00022 43.4 0.0 76 875-955 107-182 (529)
110 101 6T3F_F Fusion glycoprotein F0, 42.9 21 0.00025 42.7 0.0 76 875-955 85-160 (502)
111 102 3N27_B Fusion glycoprotein F0, 42.7 21 0.00025 34.6 0.0 28 927-954 18-45 (80)
112 103 1ZTM_C Fusion glycoprotein; fu 42.5 21 0.00026 42.4 0.0 75 876-955 90-164 (490)
113 104 4GIP_D Fusion glycoprotein F2, 42.0 22 0.00026 41.5 0.0 72 878-955 1-73 (409)
114 105 6H2E_Q AhlB; Tripartite pore-f 41.7 22 0.00027 35.5 0.0 23 1173-1195 128-150 (274)
115 106 5IJO_G Nuclear pore complex pr 40.4 24 0.00029 42.7 0.0 55 1133-1189 239-293 (599)
116 107 1WP7_A fusion protein; Nipah V 40.3 24 0.00029 34.8 0.0 28 927-954 18-45 (89)
117 108 1WP8_C fusion; Hendra Virus, F 39.6 25 0.00031 34.6 0.0 28 927-954 18-45 (89)
118 109 6R1J_J AhlB; Tripartite pore-f 39.2 26 0.00031 34.8 0.0 24 1172-1195 127-150 (272)
119 110 6C14_A Protocadherin-15, LHFPL 38.6 27 0.00032 35.4 0.0 26 1108-1133 82-109 (337)
120 111 5EJB_D Fusion glycoprotein F0; 38.0 28 0.00034 41.7 0.0 76 875-955 82-157 (501)
121 112 2M8R_A Syntaxin-1A; syntaxin, 36.7 30 0.00036 29.7 0.0 12 1211-1222 84-95 (109)
122 113 3HD7_B Vesicle-associated memb 36.7 30 0.00036 29.7 0.0 12 1211-1222 84-95 (109)
123 114 5C3L_B Nucleoporin Nup54, MGC8 34.3 35 0.00042 32.1 0.0 57 1131-1189 6-62 (142)
124 115 5G6U_A LANGERIN; CARBOHYDRATE 33.0 38 0.00046 33.5 0.0 42 1038-1090 123-164 (261)
125 116 3IPD_E Vesicle-associated memb 26.9 56 0.00068 28.7 0.0 9 1212-1220 68-76 (91)
126 117 3HD7_A Vesicle-associated memb 26.9 56 0.00068 28.7 0.0 9 1212-1220 68-76 (91)
127 118 6BP2_B Envelope Glycoprotein G 24.9 64 0.00078 35.3 0.0 40 925-964 122-161 (202)
128 119 6QD8_D Light chain, Virion spi 23.5 72 0.00087 33.9 0.0 34 931-964 61-94 (168)
129 120 4NJL_A S protein; six-helix-bu 22.6 76 0.00092 33.2 0.0 27 1178-1204 104-130 (131)
130 121 4LWS_B Uncharacterized protein 22.2 79 0.00095 26.3 0.0 32 955-986 54-85 (103)
131 122 2NRJ_A Hbl B protein; Enteroto 21.9 80 0.00097 32.4 0.0 15 1205-1219 194-208 (346)
132 123 2N2A_B Receptor tyrosine-prote 21.7 81 0.00099 26.9 0.0 23 1206-1228 1-23 (58)
133 124 6F5U_B Envelope glycoprotein,G 21.4 83 0.001 33.1 0.0 38 927-964 57-94 (168)
134 125 5F1B_B GP1, GP2, Niemann-Pick 21.4 84 0.001 31.9 0.0 37 929-965 52-88 (130)
135 126 6HS4_B Envelope glycoprotein,E 21.3 84 0.001 33.1 0.0 40 925-964 55-94 (168)
136 127 2KG7_A Uncharacterized protein 21.1 85 0.001 25.8 0.0 66 923-988 14-80 (97)
137 128 6W08_B NSP15 endoribnuclease; 20.9 87 0.0011 32.8 0.0 55 1139-1193 122-184 (359)
138 129 3OGI_C Putative ESAT-6-like pr 20.4 90 0.0011 26.8 0.0 66 921-986 11-77 (101)
139 130 5HJ3_L Envelope glycoprotein, 20.1 93 0.0011 31.8 0.0 35 930-964 60-94 (136)
140 131 6RX1_A Syncytin-1; HUMAN PLACE 20.0 93 0.0011 31.0 0.0 53 908-964 12-64 (108)
141
142 No 1
143 >6X29_A Spike glycoprotein; Trimer, VIRAL PROTEIN; 2.7A {Severe acute respiratory syndrome coronavirus 2}
144 Probab=100.00 E-value=2.9e-269 Score=2251.14 Aligned_cols=1198 Identities=99% Similarity=1.476 Sum_probs=961.9 Template_Neff=3.900
145
146 Q sp|P0DTC2|SPIK 16 VNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFAST 95 (1273)
147 Q Consensus 16 vnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtngtkrfdnpvlpfndgvyfast 95 (1273)
148 |||||||||||+||.+..+|+||||..++|++.+.+|+||+|+.+++++++|||++|++....+++++.||+||+|+...
149 T Consensus 1 ~~~~~~~~~~~~~~~~~~~g~yYpd~~~~sn~t~l~qglfp~~~s~~~~y~~~~~~gt~~~~~y~~~~~~F~dGifv~v~ 80 (1273)
150 T 6X29_A 1 VNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFAST 80 (1273)
151 T ss_dssp -----------CEEECCSCCCBCCSSEECCSEEEEEEEEECCTTCEEECCCCCC----------CCCCEECTTCEEEEEE
152 T ss_pred CCcccccCCCCCcccccceeeEeeCCeeEeecccccccccCCCCCCceEEeeEEeecCCcccccCCCCcccCCeEEEEee
153 Confidence 69999999999999999999999999999999999999999999999999999999999999999999999999999999
154
155
156 Q sp|P0DTC2|SPIK 96 EKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPF 175 (1273)
157 Q Consensus 96 eksniirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpf 175 (1273)
158 +++|..++|+||+|.+.++++++|+++.+.+.|.+|.|++|..|++.++++.+|.+|+|++++.|..++||+|+|..|+|
159 T Consensus 81 ~~~n~~p~~~fGstf~n~s~tvvI~P~~~~~~it~C~~~vC~~p~~~~~~~~g~~~~~~~~~~~~~~~~nc~f~~~~~nf 160 (1273)
160 T 6X29_A 81 EKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPF 160 (1273)
161 T ss_dssp ESSCCEEEEEEESSCSSSSCCCEEEECSSCEEEECCCCCCCSSCCEEC---------------------CCCCEEEC---
162 T ss_pred ecccCcceEeEEeccCCCcEEEEEeCCCcceEEEEEEEEecCCCeeEEEeecCCceeeeeehhhhccCCCceEEEecCCc
163 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
164
165
166 Q sp|P0DTC2|SPIK 176 LMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSS 255 (1273)
167 Q Consensus 176 lmdlegkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdss 255 (1273)
168 .||.+.++|+|...++|+|++.||+|.+|..+++++..+.+|+|+..+.|..++|+|+||+|+|.++.+.|++.+|++.+
169 T Consensus 161 t~d~~~~~~~~~~~~~~~F~~~dG~f~iY~~~~~~~~~~~~~~~~~~~~yy~~~p~g~n~~~~~~~~~~~~~~~~~~~~~ 240 (1273)
170 T 6X29_A 161 LMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSS 240 (1273)
171 T ss_dssp ----------CCEEEEEEEEEETTEEEEEEEEEECCCSSSCCSSCCCBEEEEEEECCCCCSEEEEEEEEC----------
172 T ss_pred eeccccCccceeeeEeEEEEecCCeEEEEEeCCCCcccccCCccccccchhhcCCCCCccccceeEEEeeeecCCCCCCC
173 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999889
174
175
176 Q sp|P0DTC2|SPIK 256 SGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNL 335 (1273)
177 Q Consensus 256 sgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnl 335 (1273)
178 ++|+.+.++|||+||+||+|||+|++||.||+||||+.||++|.||..+||++++|+|++|+||+||...++|+++++..
179 T Consensus 241 ~~~~~~~~~~yV~~L~~r~yLl~fd~nG~It~AvDCa~~~~sEL~Cst~SF~p~tGVY~lS~yraqP~~~V~~~~~~~~~ 320 (1273)
180 T 6X29_A 241 SGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNL 320 (1273)
181 T ss_dssp -------CCEEECCCEEEEEEEEECTTSCEEEECCTTSCHHHHHHHHHTCSSCCSEEEEEEEEECCCCCCCEECCCCCCB
182 T ss_pred cccceeeeEEEEEeccceeEEEeecCCCeEeEEEecccCcchhceeEecceecCCcEEeccCeEEEeceEEEEcCCCCCC
183 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
184
185
186 Q sp|P0DTC2|SPIK 336 CPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQT 415 (1273)
187 Q Consensus 336 cpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqt 415 (1273)
188 |+|.+++++.++.++|.|.|++++||..|+++|++..++++|+||||+|.||.++||..|++|.|.|..++.++++||++
189 T Consensus 321 C~~~~~~~~~~~Psp~~w~R~~fsNCnfn~s~Lls~~~~~~f~C~~ispskL~~mCfssvtiD~F~ip~~~~~~l~~g~~ 400 (1273)
190 T 6X29_A 321 CPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVCPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQT 400 (1273)
191 T ss_dssp CCCHHHHTCSSCCCGGGCEEEEECSSBCCHHHHHHCSCCSEEEESSSCGGGGTTCCCSEEEEEEEEECGGGGTTCSTTCC
192 T ss_pred CChhHHhcCCCCCCcceeEEEEEecCCCcHHHHhhccccceeEEeCCCHHHhcccccCeeEEEEEEecccceeecCCCCC
193 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
194
195
196 Q sp|P0DTC2|SPIK 416 GKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSY 495 (1273)
197 Q Consensus 416 gkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsy 495 (1273)
198 |.|++||||+|+||+||+++|+.++++..+.++|||++|.+++++++|||||+++|+||.+.++|+...|.+|++|+..+
199 T Consensus 401 g~i~~yNYkl~~~~~~C~l~~~~~~~~~~~t~~y~~~~~~~~~~~~~~~~~~~~~~~y~~~~~~C~~~~~~~C~~pl~~~ 480 (1273)
200 T 6X29_A 401 GKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSY 480 (1273)
201 T ss_dssp STTTTTTCCCCTTCCEEEEEEECTTTTCC--CBCCCEEC-------CTTCCCC--------------------CCSCEEC
202 T ss_pred cHHHhcCcCCCCCCCCeEEEEEeCCcccCCcccHHHHHHhcccCCCCcccCCCchhhhcCCCCCCCCCCcccceeccccc
203 Confidence 99999999999999999999999999998999999999999999999999999999999999999976799999999999
204
205
206 Q sp|P0DTC2|SPIK 496 GFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDA 575 (1273)
207 Q Consensus 496 gfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttda 575 (1273)
208 ++....|++++.+++++++++....|++|||.+..++++.++||++|..|.||+||++++|..+..+|.||.++.|+..+
209 T Consensus 481 ~~~~~~g~~~~c~~lv~IT~~~t~~~~~Vc~~~~~snI~LnvCVdYNIYGiTGqGVItntn~t~~~~q~~gl~~~g~s~g 560 (1273)
210 T 6X29_A 481 GFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDA 560 (1273)
211 T ss_dssp CBCTTC-CTTSCEEEEEEEEECCSSCCCCCCSCCCCCCCCSSEECCEETTEECCEEEEECCCCCCTTCCEEECTTSCEEE
212 T ss_pred ceecCCcccceeeEEEEEEEecCCCCCcccCCcCCceeEeceEEeeEeCCceeEEEEEecCCCCccchhcceecCCCcce
213 Confidence 88888999999999999999999999999999999999999999999999999999999999999999999999999999
214
215
216 Q sp|P0DTC2|SPIK 576 VRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEH 655 (1273)
217 Q Consensus 576 vrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaeh 655 (1273)
218 +|++.++++..|+||..+.++|+..|+|+++|+|+||..+||++++.++++.+++|.|++++++++.||||+||++||.+
219 T Consensus 561 FKn~ttG~~YsV~PC~~~~QsVVy~g~~~s~q~AgL~tSinCt~v~~~~~s~~~t~~fy~~s~~~~~~~T~~gcv~na~~ 640 (1273)
220 T 6X29_A 561 VRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEH 640 (1273)
221 T ss_dssp EECSSSCCEEEEECCCEEEEEEEECCTTTCSCCEEEEETCCTTCC--------------------CEEECSSEEEESCEE
222 T ss_pred EECCCCCCEEEEEeCcccceEEEcCCCCCcceEEEEEeccCCCCCcceeeccccCCeeEEEeCCCCceeeceeEeeccee
223 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
224
225
226 Q sp|P0DTC2|SPIK 656 VNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTS 735 (1273)
227 Q Consensus 656 vnnsyecdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtkts 735 (1273)
228 .++..+|+.|+|.|||+.+.+...+++..+.+....+..|+|.+..+..++.+...|.||+||||+|++|.++++|.|.+
229 T Consensus 641 ~t~~~~C~~Pvg~giC~d~~~~~~~~~s~~~~~~~~l~~~~~p~~~~~~~~~~~~~i~IP~nFtlsvt~EyiQt~~~kVs 720 (1273)
230 T 6X29_A 641 VNNSYECDIPIGAGICASYQTQTNSPGSASSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTS 720 (1273)
231 T ss_dssp CSSCCCCSEEEETTEEEEEEC------------CCEEEEEECCCSCEEECCCCTTEEEEEEEEEEEEEEEEEECCCCCEE
232 T ss_pred cCCCCcCCCCceEEEeecCCccCCCCCccccccceeEEeeeccCCccccccccceEEEccCCeEEEEEEEEeeecCCceE
233 Confidence 99999999999999999999843333323345667888999988887888899999999999999999999999999999
234
235
236 Q sp|P0DTC2|SPIK 736 VDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKR 815 (1273)
237 Q Consensus 736 vdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqilpdpskpskr 815 (1273)
238 |||.+|+|||+.+|.+||.|||+||..+|+||.|.+..+|.+..+++..+++.++++.+.+|+||||+.+||.+++|++|
239 T Consensus 721 IDC~~YVC~~~~rC~~LL~QYgsfC~~I~~aL~~~a~led~~~~~~~s~~~~~~~~~~~~~~~~fN~s~llp~~~~~~~R 800 (1273)
240 T 6X29_A 721 VDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKR 800 (1273)
241 T ss_dssp ECHHHHHSTTCHHHHHHHGGGCTTHHHHHHHHHHHHHHHHHHHHHHHTTSSSEEECCSSCCSTTCCCTTTSBCTTSSSCC
242 T ss_pred EecchhccCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHhcHHHHHHHHHhhHHhcCCCcccCCCccccccCCCCCCCCCc
243 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
244
245
246 Q sp|P0DTC2|SPIK 816 SFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQ 895 (1273)
247 Q Consensus 816 sfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalq 895 (1273)
248 |+||||||+||+.+|.|+.+.|.+|.++..+|||+|||.|||+.||||++++||++.||++|++|....|||||+++|..
249 T Consensus 801 SaIEDLLF~KV~t~glG~~~~Yk~Ct~g~~i~DL~CAQyyNGimVLPpv~d~~~~amYTasL~g~m~~gg~T~G~tsaaa 880 (1273)
250 T 6X29_A 801 SFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQ 880 (1273)
251 T ss_dssp BHHHHHHSSSCC--------------------------CCSSEEECCCSSCHHHHHHHHHHHHHHHHHHTTHHHHSSCCC
252 T ss_pred cHHHHHhcCceEeCCCChhHhhHHccCCccHHHHhcccccCcEEEeCCCCCHHHHHHHHHHHHHHHHhcccccCcchhcc
253 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
254
255
256 Q sp|P0DTC2|SPIK 896 IPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISS 975 (1273)
257 Q Consensus 896 ipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaiss 975 (1273)
258 |||||||.||+||+|+||+||.||||+|||.||.||+.||+.++.|++||.|+|||||++++||++|++||+.|||||||
259 T Consensus 881 iPFa~~vq~RlN~v~lt~~VL~~NQk~iA~sFN~A~~~i~~g~~tts~AL~kiQ~VVN~~~~aL~~L~~QL~nnFgAISS 960 (1273)
260 T 6X29_A 881 IPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISS 960 (1273)
261 T ss_dssp CCHHHHHHHHHHTTTCCTHHHHTTHHHHHHHHHHHHHHHHHHHSSCGGGGHHHHHHHHHHHHHHHHHGGGGGCCTTSSCS
262 T ss_pred chhHHHHHHHhcccccchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHH
263 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
264
265
266 Q sp|P0DTC2|SPIK 976 VLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQS 1055 (1273)
267 Q Consensus 976 vlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqs 1055 (1273)
268 .++||++|||++||++||||||+|||.+|++||+|||+|++|+|+|+.||..||+|||..||+|.+|||.|.|++|+||.
269 T Consensus 961 SI~dIy~RLD~leAdaQVDRLItGRL~aLnafVtQ~L~~~~evr~sr~LA~qKINECVKsQS~R~gFCGnG~Hi~S~~q~ 1040 (1273)
270 T 6X29_A 961 VLNDILSRLCPPEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQS 1040 (1273)
271 T ss_dssp CHHHHTTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSSCCCSTTSSSSSEEEECCEEE
272 T ss_pred HHHHHHHhhchhHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhccCcccCcCCCCeeEEecccc
273 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
274
275
276 Q sp|P0DTC2|SPIK 1056 APHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNN 1135 (1273)
277 Q Consensus 1056 aphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnn 1135 (1273)
278 ||+|++|+|++|+|.+.++.+++|.+|+++++..|++|+|+.|+++|++|.|++|||..||.+|..+...|||....+|+
279 T Consensus 1041 AP~Gi~F~H~~~~Pt~~~~v~a~~GlC~~~~~~~~~~g~~~~~~~~~~~T~r~~y~P~~~t~~d~v~i~sC~V~y~~vn~ 1120 (1273)
280 T 6X29_A 1041 APHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNN 1120 (1273)
281 T ss_dssp ETTEEEEEEEEEEEEEEEEEECBSCEESSSCEEEESSSEEEESSSSEEEECSSSCCCBCCBTTTEEECSCTTTSTTCEEC
282 T ss_pred CCCeEEEEEEEecccceEEEEEeceEeeCCceeeecceEEEEcCCEEEEcccccccCccCCCCceEEeccceeEEEEecc
283 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
284
285
286 Q sp|P0DTC2|SPIK 1136 TVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWP 1213 (1273)
287 Q Consensus 1136 tvydplqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqyikwp 1213 (1273)
288 ++.+|++|++..|+|||+|||||||+|+.++++++.+|++++|++.||++|+|+.|+||+++|||++|++||+|-+++
289 T Consensus 1121 t~~~~~~pd~~df~~el~~~~~N~t~p~~~~~~~~~~N~T~LNLt~EI~~Lq~~I~~LN~slIDLe~Ln~~e~y~~~~ 1198 (1273)
290 T 6X29_A 1121 TVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQGSGYI 1198 (1273)
291 T ss_dssp CCBCSHHHHHHC------------------------------------------------------------------
292 T ss_pred cccCCCCCCCCCHHHHHHHHccCCCCCCCCCCccccccccccchHHHHHHHHHHHHHHHHhcccHHHhcceeeeccCC
293 Confidence 999999999999999999999999999999999999999999999999999999999999999999999999998764
294
295
296 No 2
297 >6CS2_B Spike glycoprotein,Envelope glycoprotein, Angiotensin-converting enzyme; membrane fusion, glycoprotein, receptor binding; HET: BMA, MAN, NAG;{Human SARS coronavirus}
298 Probab=100.00 E-value=3.2e-221 Score=1857.50 Aligned_cols=1161 Identities=77% Similarity=1.263 Sum_probs=1101.0 Template_Neff=4.100
299
300 Q sp|P0DTC2|SPIK 31 SFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTL 110 (1273)
301 Q Consensus 31 sftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgttl 110 (1273)
302 +-.+|+||||..++++...-+|++|.++-++++-+|+. -.-+.+++.||+||+++...+++|.-++|+||+|.
303 T Consensus 22 ~~~~g~yYPd~~~~sN~t~L~qglfp~~gs~~~~~~~~-------~~~y~~~~~~F~dGifv~v~~~~n~~~a~~fGsTF 94 (1215)
304 T 6CS2_B 22 SSMRGVYYPDEIFRSDTLYLTQDLFLPFYSNVTGFHTI-------NHTFGNPVIPFKDGIYFAATEKSNVVRGWVFGSTM 94 (1215)
305 T ss_pred cccceeEecCCeeeccceeeeeCccCCCCCCCccCCcc-------hhhcCCCccccCCcEEEEeeEecCCCCceeeeecc
306 Confidence 45689999999999999999999999999999987776 34577889999999999999999998899999999
307
308
309 Q sp|P0DTC2|SPIK 111 DSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLR 190 (1273)
310 Q Consensus 111 dsktqsllivnnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknlr 190 (1273)
311 +..+++++|+++-+...|.+|.|..|..|...+++.-.| -.+++.|..+.||+|.|.|+.|-+|...+-.+....+
312 T Consensus 95 ~N~s~tvVI~P~~~~~~it~C~~~vC~~p~~~~~p~~gn----~~~~~~~~~~~nc~f~~~~~nfT~d~~~~~~~~~~r~ 170 (1215)
313 T 6CS2_B 95 NNKSQSVIIINNSTNVVIRACNFELCDNPFFAVSKPMGT----QTHTMIFDNAFNCTFEYISDAFSLDVSEKSGNFKHLR 170 (1215)
314 T ss_pred cCCceEEEEcCCCCcceeeEeEEEeCCCCceeEcCCCCC----cccccceeecCCceEEEcccccccccccceeeeeEEE
315 Confidence 999999999999999999999999999999988874443 4678889999999999999999999888888888899
316
317
318 Q sp|P0DTC2|SPIK 191 EFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYL 270 (1273)
319 Q Consensus 191 efvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgyl 270 (1273)
320 +|+|++.||+|-+|-.+.+.+..+.+|.|...|.|..-+|..++|+.|..++ -.|| ++ .+.|+...++|||.+|
321 T Consensus 171 ~f~F~~~~G~fy~Y~a~~~~~~f~~~~~~~~~l~yy~vip~~~~~~~~~~~~-~~~~--~~---~~~~~~~~~~~yv~~L 244 (1215)
322 T 6CS2_B 171 EFVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIFKLPLGINITNFRAIL-TAFS--PA---QDIWGTSAAAYFVGYL 244 (1215)
323 T ss_pred EEEEEecCCeEEEEeecCCCcccccCCCCcccceeeEeeceecccccceEEe-eecC--CC---CCcccccceEEEEeec
324 Confidence 9999999999999988877777899999999999999999999999998872 2233 22 5677888999999999
325
326
327 Q sp|P0DTC2|SPIK 271 QPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASV 350 (1273)
328 Q Consensus 271 qprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasv 350 (1273)
329 .+|+++|.|..||+|+|++||+-+|.+|-+|.-.+|....|.|..++++++|.-...|.......|+|.+++++.++.++
330 T Consensus 245 ~~~~~lLayf~NGti~dvIdC~~sp~~~LaCqy~T~nfsdGvYp~s~~~vk~~fiVyr~~~~~~~C~~~~~~~~~~~Psp 324 (1215)
331 T 6CS2_B 245 KPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVVRFPNITNLCPFGEVFNATKFPSV 324 (1215)
332 T ss_pred eeceeehHHhcCCeEEEEEECCCCcccceeceeceeccCCCeeeccceEeeceEEEEECCCCCCCCCHHHHhhCCCCCCc
333 Confidence 99999999999999999999999999999999999999999999999999999999999988899999999999999999
334
335
336 Q sp|P0DTC2|SPIK 351 YAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFT 430 (1273)
337 Q Consensus 351 yawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddft 430 (1273)
338 |.|.|+.++||..|+++|++..++++|+||||||.||.+.||..|++|.|.|..+..++++||++|.|++||||+|+||+
339 T Consensus 325 ~~w~R~~fsnCnfn~s~Lls~~~~~~f~C~gIspskLa~mCfsSvtiD~F~ip~s~~~~l~~g~~g~i~~~NYkl~~~~~ 404 (1215)
340 T 6CS2_B 325 YAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFSNVYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFM 404 (1215)
341 T ss_pred cceeEeEEecCCCCHHHHHhcceeeeeEeeCCCHHHHcccccCeeeEEEeeccccchhhcCCCCCchHHhcccCCCCCCC
342 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
343
344
345 Q sp|P0DTC2|SPIK 431 GCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRV 510 (1273)
346 Q Consensus 431 gcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpyrv 510 (1273)
347 ||+++|+-.+++..+..++|+.++-.|+..++|+++|.+.--+.-...+|. ..|-.|..++..|.+...-|+|++++++
348 T Consensus 405 ~C~l~~~~~~~~vn~t~~~n~~~~~~r~~~~~~~~~d~~~CPf~~~~s~C~-~~~~~~~~~i~~~~~~~~~g~~~~~~g~ 483 (1215)
349 T 6CS2_B 405 GCVLAWNTRNIDATSTGNYNYKYRYLRHGKLRPFERDISNVPFSPDGKPCT-PPALNCYWPLNDYGFYTTTGIGYQPYRV 483 (1215)
350 T ss_pred ceEEEEEcCccceeccCCCCcccccccccceeecCCCCCCCCCCCCCCCCC-CCCCCCCcccccccceeeccccceeeEE
351 Confidence 999999988888776667777766666666889999888744444467884 3666777788888765567999999999
352
353
354 Q sp|P0DTC2|SPIK 511 VVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPC 590 (1273)
355 Q Consensus 511 vvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpc 590 (1273)
356 ++++++....|++|||+|..+.++.+.||++|+.|.||+||++|+|..+..+|.|+.|..+-..++||+.|+++..|+||
357 T Consensus 484 lvis~k~~~~p~tVCg~~~~T~l~ldvCV~YnIYGiTGtGVi~~sn~t~~sgqsf~~ds~GfL~gfKn~ttG~iYsI~PC 563 (1215)
358 T 6CS2_B 484 VVLSFELLNAPATVCGPKLSTDLIKNQCVNFNFNGLTGTGVLTPSSKRFQPFQQFGRDVSDFTDSVRDPKTSEILDISPC 563 (1215)
359 T ss_pred EEEEEEEcCCCCcccCCcCccceeeceeEeEEeCCceeeEEEEecCcEecCCeeeEEeCCcceeEEEeCCCCCEEEEeeC
360 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
361
362
363 Q sp|P0DTC2|SPIK 591 SFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGI 670 (1273)
364 Q Consensus 591 sfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsyecdipigagi 670 (1273)
365 .++.|||+.+|.++|+..|+||..++|+++....+..+.+|.|+.++++.+.|||-+||++||++.+...+|++|+|.|+
366 T Consensus 564 ~s~~VSVVy~g~~sS~~~alLf~~v~C~~v~~~~~~~~~~p~~~~~s~~~~~fdT~~GCv~na~n~~~v~~C~lplG~Gl 643 (1215)
367 T 6CS2_B 564 AFGGVSVITPGTNASSEVAVLYQDVNCTDVSTAIHADQLTPAWRIYSTGNNVFQTQAGCLIGAEHVDTSYECDIPIGAGI 643 (1215)
368 T ss_pred eecceEEEEcCCccCCCcceeccccccccccccccceeecCceEEeeCCCCCcccccceeecccCCCcccccCcccccee
369 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
370
371
372 Q sp|P0DTC2|SPIK 671 CASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECS 750 (1273)
373 Q Consensus 671 casyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecs 750 (1273)
374 |+.+.+ .++.|+....++..|+++++....++.+...|.||+||||+|++|-++++|.|.+|||.+|+||++.+|.
375 T Consensus 644 C~d~~~----~~~~~~~~~~~~~~y~~p~~~~s~~~~~~~~i~IP~nft~~v~~Eyiq~~~~kv~idC~~YVC~~~~~C~ 719 (1215)
376 T 6CS2_B 644 CASYHT----VSLLRSTSQKSIVAYTMSLGADSSIAYSNNTIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECA 719 (1215)
377 T ss_pred ecCCCc----eeeccCCCceeeeeeecCCCCCCCCCceeeEEEccCCeEEEEEEEEeeecCCCeEEechhhccCCCHHHH
378 Confidence 999988 3333335566778999998765578888999999999999999999999999999999999999999999
379
380
381 Q sp|P0DTC2|SPIK 751 NLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLAD 830 (1273)
382 Q Consensus 751 nlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtlad 830 (1273)
383 +||.|||+||..+|+||.+.+..+|.+..+++...++-++.|-+..||||||+.+||.++++++||+||||||+||..+|
384 T Consensus 720 ~lL~qYgs~C~~I~~al~~~~~l~d~~~~~~~~~~~~~~~~~~~~~~~~~n~s~~l~~~~~~~~RS~iEDLLF~KV~t~g 799 (1215)
385 T 6CS2_B 720 NLLLQYGSFCTQLNRALSGIAAEQDRNTREVFAQVKQMYKTPTLKYFGGFNFSQILPDPLKPTKRSFIEDLLFNKVTLAD 799 (1215)
386 T ss_pred HHHHHHHHHHHHHHHHHHHHHhHHhHHHHHHHHhcccCCCCCcccccCCccchhcCCCCCCCCCccHHHHHHcCeeeeCC
387 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
388
389
390 Q sp|P0DTC2|SPIK 831 AGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIG 910 (1273)
391 Q Consensus 831 agfikqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngig 910 (1273)
392 .|+.+.|.+|.+...+|||+|||.+||+.||||++++||++.||++|++|....|||||+|+|..|||||||.||+||+|
393 T Consensus 800 ~g~~~~Y~~C~~g~~i~DL~CaQ~ynGi~VLP~v~~~~~~a~YT~sl~g~ma~gg~T~g~~sa~aiPFa~~vq~RlN~v~ 879 (1215)
394 T 6CS2_B 800 AGFMKQYGECLGDINARDLICAQKFNGLTVLPPLLTDDMIAAYTAALVSGTATAGWTFGAGAALQIPFAMQMAYRFNGIG 879 (1215)
395 T ss_pred CCchhhHhhccCCccHHHHhcccccCeEEEeCCCCCHHHHHHHHHHHHHHHHhccccccccccccccHHHHHHHHhchhh
396 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
397
398
399 Q sp|P0DTC2|SPIK 911 VTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAE 990 (1273)
400 Q Consensus 911 vtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkveae 990 (1273)
401 +||+||.||||+|||.||.||+.||+.++.+++||.|+||||||+++||++|++||+.|||||||.++||++|||++||+
402 T Consensus 880 l~~~vL~~NQk~iA~sFN~A~~~i~~g~~t~~~Al~kiQ~VVN~~~~aL~~L~~qL~~nFgAISssi~dIy~RLd~leAd 959 (1215)
403 T 6CS2_B 880 VTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDPPEAE 959 (1215)
404 T ss_pred ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHH
405 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
406
407
408 Q sp|P0DTC2|SPIK 991 VQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPA 1070 (1273)
409 Q Consensus 991 vqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpa 1070 (1273)
410 +||||||+|||.+|++||+|+|+|++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+||.||+|++|+|.+|+|.
411 T Consensus 960 aQvDRLItGRL~aLna~vtq~l~~~~~v~~sr~lA~qKinECVksQS~R~gFCGnG~Hi~S~~q~AP~Gi~F~H~~~~Pt 1039 (1215)
412 T 6CS2_B 960 VQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYVPS 1039 (1215)
413 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcccCcCCCCCCeeeEeecccCCCeEEEEEEeeccc
414 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
415
416
417 Q sp|P0DTC2|SPIK 1071 QEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKE 1150 (1273)
418 Q Consensus 1071 qeknfttapaichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydplqpeldsfke 1150 (1273)
419 +.++.+++|.+|+++++..|++|+|+.|++.|++|.|++|||..||.+|...-..|||....+|+++.+|++|++..|+|
420 T Consensus 1040 ~~~~v~a~~GlC~~~~~~~~~~g~f~~~~~~~~~T~r~~y~P~~~t~~d~v~i~sC~V~y~nvn~~~~~~~~p~~~df~~ 1119 (1215)
421 T 6CS2_B 1040 QERNFTTAPAICHEGKAYFPREGVFVFNGTSWFITQRNFFSPQIITTDNTFVSGNCDVVIGIINNTVYDPLQPELDSFKE 1119 (1215)
422 T ss_pred ceeEEEEEceeeeCCCceeecceEEEEcCcEEEEeccccccCCCCChhceEEeecCceeEEeecCCCCCCCCCCCCCHHH
423 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
424
425
426 Q sp|P0DTC2|SPIK 1151 ELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWP 1213 (1273)
427 Q Consensus 1151 eldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqyikwp 1213 (1273)
428 ||++|+||||+|+.+++++..+|++++|++.||++|+|+.|+||+++|||++|++||+|-+|+
429 T Consensus 1120 el~~~~~N~t~p~~~~~~~~~~N~t~LnLt~EI~~L~~~i~~LN~s~IDLe~L~~~e~ya~~~ 1182 (1215)
430 T 6CS2_B 1120 ELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQGSGYI 1182 (1215)
431 T ss_pred HHHHHhcCCCCCCCCCCChhhccccccchHHHHHHHHHHHHHHHhcCcCHHHhcceeHhhcCC
432 Confidence 999999999999999999999999999999999999999999999999999999999998875
433
434
435 No 3
436 >6Q04_B Spike glycoprotein; Coronavirus, spike glycoprotein, MERS-CoV, membrane; HET: MAN, SIA, NAG, FOL, BMA; 2.5A {Human betacoronavirus 2c EMC/2012}
437 Probab=100.00 E-value=1.8e-204 Score=1723.92 Aligned_cols=1150 Identities=31% Similarity=0.496 Sum_probs=897.1 Template_Neff=3.700
438
439 Q sp|P0DTC2|SPIK 31 SFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG--T-------KRFDNPVLPFNDGVYFASTEKSNII 101 (1273)
440 Q Consensus 31 sftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng--t-------krfdnpvlpfndgvyfasteksnii 101 (1273)
441 +-.+|+||||..++++..+-.|++|.+.-++.+-.- ++|++. + -.++.+..||+||+++...+.+|--
442 T Consensus 65 s~~~G~yYPd~rvysN~TlL~qglfP~~gs~~~~y~---~~~t~~~s~~~~~~~~~~y~~~~~~F~dGifvkv~~~~n~t 141 (1359)
443 T 6Q04_B 65 SKADGIIYPQGRTYSNITITYQGLFPYQGDHGDMYV---YSAGHATGTTPQKLFVANYSQDVKQFANGFVVRIGAAANST 141 (1359)
444 T ss_dssp GGTTTCBCCTTCEECSEEEEEEEEECCTTCCCEEEC---CEECCEETTEECSEEECSCTTCCEECTTCEEEEESTTTTSE
445 T ss_pred ccCceeEeeCCeeEeeeeeeeeceecCCCCcceEEE---EEecCCCCCCCcceeeeccCCChhhccCeEEEEEeeeecCC
446 Confidence 346899999999999999999999999988876542 333332 1 3567789999999999888766643
447
448
449 Q sp|P0DTC2|SPIK 102 R-----------------GWIFGTTLDSKT---Q------SLLIVNNATNVVI-------KVCEFQFCNDPFLGVYYHKN 148 (1273)
450 Q Consensus 102 r-----------------gwifgttldskt---q------sllivnnatnvvi-------kvcefqfcndpflgvyyhkn 148 (1273)
451 . .++||+|.+... + +++|+++-.+.++ ...+..-|..|..-+++.-+
452 T Consensus 142 g~~~~~~~~~~~~~~~ypa~~fGsTF~Nts~~~~~~~~~~tlVI~P~~~g~~~~~~~c~~~prtit~C~~p~~~~~p~~~ 221 (1359)
453 T 6Q04_B 142 GTVIISPSTSATIRKIYPAFMLGSSVGNFSDGKMGRFFNHTLVLLPDGCGTLLRAFYCILEPRSGNHCPAGNSYTSFATY 221 (1359)
454 T ss_dssp EEETTEEEEEEEEECCCCCEEEESCEEECTTSCEEEECSEEEEEEEETTTTEEEEEEEEEEECCSBTSTTSSSCCCCCEE
455 T ss_pred CCeeeCCccccchhhhccceEeeccccCCCCCccccccceEEEEecCCCCchheeeeecccccccCcCCCCCeEeeeeec
456 Confidence 2 256999998666 5 8899988887543 32333345555555554222
457
458
459 Q sp|P0DTC2|SPIK 149 N---KSWMES---------EFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNID-GYFKIYSKHTPINL--- 212 (1273)
460 Q Consensus 149 n---kswmes---------efrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknid-gyfkiyskhtpinl--- 212 (1273)
461 . .+|..+ +++.|....+|+|.|. +.|-+|... ..|- |.|+..| |.|-+|.-++..+.
462 T Consensus 222 ~~~~~~~~~~~~~~n~~~~~~~~~~~~~~~~~~~~-~nfT~d~~~--~wf~----~~F~~~~~G~f~~Y~~d~~~~~~f~ 294 (1359)
463 T 6Q04_B 222 HTPATDCSDGNYNRNASLNSFKEYFNLRNCTFMYT-YNITEDEIL--EWFG----ITQTAQGVHLFSSRYVDLYGGNMFQ 294 (1359)
464 T ss_dssp ECHHHHBCSSCBCTTHHHHHHHHHEEEEEEEEEEE-EECCCCCCC--EEEE----EEEETTEEEEEESTTTCTTTCCBEE
465 T ss_pred CCCCccCCCCcccccccccchhHhcccCCceEEEe-eecCcchhh--heee----EEeeecCceeEEEEEEecCCCccee
466 Confidence 1 245333 6778889999999875 344333211 1121 9999999 99999876654432
467
468
469 Q sp|P0DTC2|SPIK 213 VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCA 292 (1273)
470 Q Consensus 213 vrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdca 292 (1273)
471 ..-+| |+..+.+.. .+-|+..++ .+.+. ..++|||++|.+|+|||+|++||.|++||||+
472 T Consensus 295 f~~~~-~~~~~~yy~---------------v~p~~~~~~---~~~~~-~~~~~yv~~L~~~~~Ll~fd~nG~I~~avDC~ 354 (1359)
473 T 6Q04_B 295 FATLP-VYDTIKYYS---------------IIPHSIRSI---QSDRK-AWAAFYVYKLQPLTFLLDFSVDGYIRRAIDCG 354 (1359)
474 T ss_dssp EEEEC-CCSCCCEEE---------------ECCEEECCC---GGGCC-EECCEEEEECEEEEEEEEECTTSCEEEEEETT
475 T ss_pred ccccc-ceeccceee---------------eeeeeecCC---ccccc-eeEEEEEEEccceeEEEeecCCCeEEEEEecC
476 Confidence 12222 444444443 233444444 34455 77899999999999999999999999999999
477
478
479 Q sp|P0DTC2|SPIK 293 LDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSA 372 (1273)
480 Q Consensus 293 ldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsa 372 (1273)
481 -|+++|-||..+||.+++|+|++|+||+||....+|.++. ..|+|.++++ .++.++|.|.|+.++||..|+|+|++..
482 T Consensus 355 ~~~~sEL~C~~~sf~~~tGVY~~S~y~aqp~~~v~~~~~~-~~C~~~~~~~-~~~P~p~~w~R~~f~nCnfN~s~Lls~~ 432 (1359)
483 T 6Q04_B 355 FNDLSQLHCSYESFDVESGVYSVSSFEAKPSGSVVEQAEG-VECDFSPLLS-GTPPQVYNFKRLVFTNCNYNLTKLLSLF 432 (1359)
484 T ss_dssp SCHHHHHHHHTTSSCCCSEEEEEEEECCCCSCEEEECCCS-CBCCCGGGGS-BCCCBGGGCEEEEECSEEECHHHHHTTS
485 T ss_pred CCccchheeEeceecCCCCeeecCCEEEEeeeEEEEecCC-CCCCchHHhc-CCCCCcceeEEeEEecCCCcHHHHHhhc
486 Confidence 9999999999999999999999999999999999999999 9999999999 8899999999999999999999999999
487
488
489 Q sp|P0DTC2|SPIK 373 SFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKV--GGNYN 450 (1273)
490 Q Consensus 373 sfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskv--ggnyn 450 (1273)
491 .+++|+||||+|.||.+.||..|++|.|.|..+..++++||++|-|++||||+|+||+||+++|+-...+..+ -.+|+
492 T Consensus 433 ~~~sF~C~gIspskLa~mCfsSvtiD~Faip~~~k~~Lq~G~~G~i~~yNYKld~~~~gC~l~y~~pa~~vn~t~p~~y~ 512 (1359)
493 T 6Q04_B 433 SVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVSSAGPISQFNYKQSFSNPTCLILATVPHNLTTITKPLKYS 512 (1359)
494 T ss_dssp EEEEEEEESSCHHHHTTCCBSEEEEEEEECCGGGGGGGSTTBCSHCCCCCCCCCSSSCEEEEEEECCTTCTTBCCCSEEE
495 T ss_pred eeeeeeecCCCHHHHcccccceeeEEEEecCccccceecCCCCChhhhccccCCCCCCccEEEEEcCccccccCCCccce
496 Confidence 9999999999999999999999999999999999999999999999999999999999999999955533322 44555
497
498
499 Q sp|P0DTC2|SPIK 451 YLYRLFRKSNLKPFERDISTEI---YQAGSTPCNGV-EGFNCYFPLQSY-----------GFQP----TNGVGYQPYRVV 511 (1273)
500 Q Consensus 451 ylyrlfrksnlkpferdistei---yqagstpcngv-egfncyfplqsy-----------gfqp----tngvgyqpyrvv 511 (1273)
501 |+.|-+++.. ++. ++. ..+ .+-|+-. ...+|+.|...+ |..| ..++++|++.++
502 T Consensus 513 yi~~~~~~~~-----~~~-~~~~~~~~~-~~~cpc~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~ 585 (1359)
503 T 6Q04_B 513 YINKCSRLLS-----DDR-TEVPQLVNA-NQYSPCVSIVPSTVWEDGDYYRKQLSPLEGGGWLVASGSTVAMTEQLQMGF 585 (1359)
504 T ss_dssp EEEEEEEECT-----TSS-CEEECCCCT-TSCCGGGGTSCSSCSSTTCEEEEECCGGGTSSEEEEEEEEEECCSSCEEEE
505 T ss_pred eeeeeeccCC-----CCC-Ccchhhccc-cccCCCCccCCccccCCCCccccccccccCCchhcccccccccccceeEEE
506 Confidence 5555555333 222 222 111 1112100 112455543322 2333 458999999999
507
508
509 Q sp|P0DTC2|SPIK 512 VLSFELLHAPATVCGP-----KKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILD 586 (1273)
510 Q Consensus 512 vlsfellhapatvcgp-----kkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleild 586 (1273)
511 |++++..+.++|||++ |.+|.++.++||++++.|+||+||++|+++.+.++|+|..|-.+-..++|| +++++.+
512 T Consensus 586 Vis~k~~~~s~tVCp~~~d~~~~~T~~~lg~CVnY~LYGiTGtGVf~~s~~~~~s~Q~f~yDs~Gnl~gf~d-~tn~~Y~ 664 (1359)
513 T 6Q04_B 586 GITVQYGTDTNSVCPKLEFANDTKIASQLGNCVEYSLYGVSGRGVFQNCTAVGVRQQRFVYDAYQNLVGYYS-DDGNYYC 664 (1359)
514 T ss_dssp EEEEESSSSCCCEEECCCCCTTSCSGGGTTSEEEEEETTEEEEEEEEECCCCSCGGGCEEECTTSCEEEEEC-TTSCEEE
515 T ss_pred EEEeEcCCCcCccCCCccccCCCCcchhcCceeEEEecceeeeeEEEecCceeecceeeEEeCCCCEEEEEe-CCCCEEE
516 Confidence 9999999999999998 667999999999999999999999999999999999999999999999999 8999999
517
518
519 Q sp|P0DTC2|SPIK 587 ITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRV--YSTGSNVFQTRAGCLIGAEHVNN-SYECD 663 (1273)
520 Q Consensus 587 itpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrv--ystgsnvfqtragcligaehvnn-syecd 663 (1273)
521 |.||..|+|||+++++ ++.+|+||++++|.+|+...+..+.+|.||+ +++..+.|||-+||++||++.+. .+|||
522 T Consensus 665 I~PC~sg~VSV~y~~~--s~e~AlLf~~l~C~~v~~~~~~~~~~~~~~l~~~~~~~~~fdT~~GCVvnA~n~t~~V~~C~ 742 (1359)
523 T 6Q04_B 665 LRACVSVPVSVIYDKE--TKTHATLFGSVACEHISSTMSQYSRSTRSMLKRRDSTYGPLQTPVGCVLGLVNSSLFVEDCK 742 (1359)
524 T ss_dssp EECCCCEEEEEEEETT--TTEEEEEEETCCGGGC---------------------CCCEEETTEEEESEEEEEEEESSCS
525 T ss_pred EeeceEEeeeEEEcCC--CCCeEEEEccccccHhhcceeeccCCCccccccccCCCCCCCCccceeeeceecCCceeeCC
526 Confidence 9999999999999998 8999999999999999999999999999998 77788999999999999999988 89999
527
528
529 Q sp|P0DTC2|SPIK 664 IPIGAGICASYQTQTNSPR-RARSVAS-QSII--AYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCT 739 (1273)
530 Q Consensus 664 ipigagicasyqtqtnspr-rarsvas-qsii--aytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdct 739 (1273)
531 +|+|.|+|+.|.+...+.| +.|++.. ..+. +|+|.+-. .++.+++..|.||+||||+|++|-++++|.|.+|||.
532 T Consensus 743 LplG~glC~~y~~~s~~~~r~~~~~~~~~~l~~~~y~~P~~~-~~~~~~~~~i~IP~nFt~~v~~EyiQ~~~~kv~iDC~ 821 (1359)
533 T 6Q04_B 743 LPLGQSLCALPDTPSTLTPASVGSVPGEMRLASIAFNHPIQV-DQLNSSYFKLSIPTNFSFGVTQEYIQTTIQKVTVDCK 821 (1359)
534 T ss_dssp SEEETTEEEECCCC------------CCEEEEEECCCCCEEC-CCCSSSCEEEEECSEEEEEEEEEEEECCCCEEEECHH
535 T ss_pred CCCCceeecCCCCCCCCCCcccCCCCCceEEEEEeecCCeee-cccCCCCeeEEcccceEEEEEEEEEeecCCceEEech
536 Confidence 9999999999998774433 3343333 3344 77787766 7888999999999999999999999999999999999
537
538
539 Q sp|P0DTC2|SPIK 740 MYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDF-GGFNFSQILPDPS---KPSKR 815 (1273)
540 Q Consensus 740 myicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdf-ggfnfsqilpdps---kpskr 815 (1273)
541 +|+||++.+|.+||.|||+||..+|+||.|.+.++|.+..+++..+++-++.+-+..| |+|||+.+||... ++++|
542 T Consensus 822 ~YVC~~~~~C~~lL~qYgs~C~~I~~aL~~~~~~~d~~~~~~~~~~~~~~~~~~~~~f~~~~N~s~ll~~~~~~~~~~~R 901 (1359)
543 T 6Q04_B 822 QYVCNGFQKCEQLLREYGQFCSKINQALHGANLRQDDSVRNLFASVKSSQSSPIIPGFGGDFNLTLLEPVSISTGSRSAR 901 (1359)
544 T ss_dssp HHHHTTCHHHHHHHGGGCSHHHHHHHHHHHHHHHHHHHHHHHHHHHCCSEECCCCTTTTTTSCCTTTSBC--------CC
545 T ss_pred hhccCCCHHHHHHHHHHHHHHHHHHHHHHHHHhhccHHHHHHHHhccccccCCCcCCCCCCcccceeccCCCCCCCccce
546 Confidence 9999999999999999999999999999999999999999999999999998888887 5799999999875 34689
547
548
549 Q sp|P0DTC2|SPIK 816 SFIEDLLFNKVTLADAGFIKQYGDCLGDI--AARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAA 893 (1273)
550 Q Consensus 816 sfiedllfnkvtladagfikqygdclgdi--aardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaa 893 (1273)
551 |+||||||+||.+.+.||...|+.|.... ..+||+|||.+||+.||||..++||.++|+.+++.+....||++|..++
552 T Consensus 902 S~ieDLLF~Kv~~~~~G~~~~y~~c~~g~~~~i~Dl~caq~~NGi~VLP~v~~~~le~~Yt~SdvG~l~~~r~e~G~tsa 981 (1359)
553 T 6Q04_B 902 SAIEDLLFDKVTIADPGYMQGYDDCMQQGPASARDLICAQYVAGYKVLPPLMDVNMEAAYTSSLLGSIAGVGWTAGLSSF 981 (1359)
554 T ss_dssp BHHHHHHHHTSCCCCCCTTTHHHHHHHTCCSSTTCTTTTHHHHTEEEECCSSCHHHHHHHHHHHHTTHHHHSSSSSSSCE
555 T ss_pred eHHHHHhcceeeeCCCCcccChhhhcccCCccHHHHhheeEeCCEeecCCccCHHHHHHHHHHHHHhhhcccccccCCcc
556 Confidence 99999999999999999999999999555 8999999999999999999999999999999999988888999999999
557
558
559 Q sp|P0DTC2|SPIK 894 LQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAI 973 (1273)
560 Q Consensus 894 lqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgai 973 (1273)
561 ..|||++++.+|+|+++++|++|.+|||.|||.||.|||.||+.+.++++||.|+|++||+++++|++|..||+.|||||
562 T Consensus 982 aaIpfs~~Vy~RLN~l~~~~~vL~~nq~~Ia~sFN~AI~~iq~Gf~t~~~Al~kIq~vVN~~~~aLs~L~~qLn~nFgAI 1061 (1359)
563 T 6Q04_B 982 AAIPFAQSIFYRLNGVGITQQVLSENQKLIANKFNQALGAMQTGFTTTNEAFQKVQDAVNNNAQALSKLASELSNTFGAI 1061 (1359)
564 T ss_dssp EECCHHHHHHHHHHTTTCCHHHHHHTHHHHHHHHHHHHHTTTTCCSTTCHHHHHHHHHHHHHHHHHHHHHHHTTCCTTSS
565 T ss_pred ccCCchHHHHHHHHhhhchHHHHHHHHHHHHHHHHHHHHHHhhccccHHHHHHHHHHHHHHHHHHHHHHHHHHhhhcccc
566 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
567
568
569 Q sp|P0DTC2|SPIK 974 SSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFP 1053 (1273)
570 Q Consensus 974 ssvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfp 1053 (1273)
571 ||.+++|+.|||++||++|+||||+|||.+|++||+|||+|++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+|
572 T Consensus 1062 Sssi~gI~~RLd~lEA~iqvdrlInGRL~aLnafVtq~l~~~~~v~~sr~LA~qKiNECVKSQS~R~gFCGnGtHi~S~~ 1141 (1359)
573 T 6Q04_B 1062 SASIGDIIQRLDPPEQDAQIDRLINGRLTTLNAFVAQQLVRSESAALSAQLAKDKVNECVKAQSKRSGFCGQGTHIVSFV 1141 (1359)
574 T ss_dssp CSCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCSSCCCSTTTSSSSEEEEEEE
575 T ss_pred hhcHhHHHHhcchHHHHhCCChhhhcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcccccCCCCCCeeEEEEe
576 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
577
578
579 Q sp|P0DTC2|SPIK 1054 QSAPHGVVFLHVTYVPAQEKNFTTAPAICHD---GKAHFPREGVFVSNG-----THWFVTQRNFYEPQIITTDNTFVSGN 1125 (1273)
580 Q Consensus 1054 qsaphgvvflhvtyvpaqeknfttapaichd---gkahfpregvfvsng-----thwfvtqrnfyepqiittdntfvsgn 1125 (1273)
581 |.||+|++|+|++|+|.+.++.+++|.+|++ +++..|+.|.|+.+. .+|++|.|++|||..||.+|+. --.
582 T Consensus 1142 q~AP~Gi~F~H~~~~Pt~~~~V~a~~GlC~~~~~~~~~~p~~g~~v~~~~~~~~~~~~~T~r~~y~P~~~t~~dv~-i~s 1220 (1359)
583 T 6Q04_B 1142 VNAPNGLYFMHVGYYPSNHIEVVSAYGLCDAANPTNCIAPVNGYFIKTNNTRIVDEWSYTGSSFYAPEPITSLNTK-YVA 1220 (1359)
584 T ss_dssp EEETTEEEEEEEEEEEESCEEEEEESCEEESSSTTCEEEESSEEEEEC-------CEEEEETTEEEEECCCTTSEE-EEC
585 T ss_pred eccCCeEEEEEEEeccCceeEEEEEeEEecCCCCCceeeccCeEEEEeCCceeeceEEEeCCccccCccCCccCEE-EEC
586 Confidence 9999999999999999999999999999996 689999999999876 5799999999999999999955 577
587
588
589 Q sp|P0DTC2|SPIK 1126 CDVVIGIVNNTVYDPL--QPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 1203 (1273)
590 Q Consensus 1126 cdvvigivnntvydpl--qpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqel 1203 (1273)
591 |||....+|+++..|+ +|+...|+|||+|+|||+++...|+.+++.+|++++|++.||++|+|+.|+||+++|||++|
592 T Consensus 1221 c~V~y~n~~~~~l~~~v~~pdyiDf~~el~~~~~n~~~~~p~l~~l~~~N~T~LNLt~EI~~Lq~~i~~LN~s~idLe~L 1300 (1359)
593 T 6Q04_B 1221 PQVTYQNISTNLPPPLLGNSTGIDFQDELDEFFKNVSTSIPNFGSLTQINTTLLDLTYEMLSLQQVVKALNESYIDLKEL 1300 (1359)
594 T ss_dssp CCTTSEEECSSCCTTTCC--------------------------------------------------------------
595 T ss_pred CcceeEecCCCCCCCccCCCCCCChHHHHHHHHhcCCCCCCCCCccccceeeecchHHHHHHHHHHHHHHHhcCCCHHHh
596 Confidence 8999999999999984 67999999999999999999888888899999999999999999999999999999999999
597
598
599 Q sp|P0DTC2|SPIK 1204 GKYEQYIKWPWYIWLGFIAGL 1224 (1273)
600 Q Consensus 1204 gkyeqyikwpwyiwlgfiagl 1224 (1273)
601 ++||+||||||||||||-.|-
602 T Consensus 1301 n~~e~YiKWPWYvWL~~~~~~ 1321 (1359)
603 T 6Q04_B 1301 GNYTYYNKGSGRENLYFQGGG 1321 (1359)
604 T ss_dssp ---------------------
605 T ss_pred CceeEEeccCchhheeecCCC
606 Confidence 999999999999999998763
607
608
609 No 4
610 >5I08_C Spike glycoprotein; coronavirus, glycoprotein, prefusion, VIRAL PROTEIN; 4.04A {Human coronavirus HKU1 (isolate N5)}
611 Probab=100.00 E-value=1.5e-199 Score=1685.13 Aligned_cols=1142 Identities=29% Similarity=0.491 Sum_probs=772.9 Template_Neff=4.000
612
613 Q sp|P0DTC2|SPIK 30 NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG---TKRFDNPVLPFNDGVYFASTEKSNI------ 100 (1273)
614 Q Consensus 30 nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng---tkrfdnpvlpfndgvyfasteksni------ 100 (1273)
615 -+-.+|+||||..++++..+-.|+||.+.-++.+-.- .+|++- --.++++..||+||+++...+.+|-
616 T Consensus 29 vs~~~G~yYPd~rvysN~TlL~qglfp~~gs~~~~y~---~~~t~~~~~~~~y~~~~~~F~dGifvkv~~~~n~t~~~~~ 105 (1299)
617 T 5I08_C 29 VSLGLGTYYVLNRVYLNTTLLFTGYFPKSGANFRDLA---LKGSIYLSTLWYKPPFLSDFNNGIFSKVKNTKLYVNNTLY 105 (1299)
618 T ss_dssp TTSSSSCBCCTTEECCSEEEEEEEEECCTTCEEEECC---CBCSSCEEGGGGSTTTEEECSSEEEEEEECCCEESSSCEE
619 T ss_pred cccceeEEEecceEEeceeeeeeCeecCCCCceeeee---eecccccccceecCCCcccccCcEEEEeeecccCCCCccc
620 Confidence 3556899999999999999999999999988876542 233332 3467888999999999998887764
621
622
623 Q sp|P0DTC2|SPIK 101 --IRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMD 178 (1273)
624 Q Consensus 101 --irgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmd 178 (1273)
625 -..++||+|.+...++++|+++-+...|.+|.|..|..|.+.+++ |..+.. +++. ....+|+|.|. +.|-+|
626 T Consensus 106 ~~~pa~~fGsTF~N~s~tvVI~P~~~~~~it~C~~~vC~~p~~~~~p--~~~~~~--~~~~-~d~~~~~~~~~-~nfT~d 179 (1299)
627 T 5I08_C 106 SEFSTIVIGSVFVNTSYTIVVQPHNGILEITACQYTMCEYPHTVCKS--KGSIRN--ESWH-IDSSEPLCLFK-KNFTYN 179 (1299)
628 T ss_dssp CCCCCEEEESSCSTTSCEEEEEEETTEEEEEEECCCCCSSCCBCCSS--SCCSCC--CTTS-TTCSCCCEEEE-EEEECC
629 T ss_pred eecceeEEeccccCCcEEEEEeCCCceEEEEEEEEEecCCCceEEec--CCCccc--eeee-EeCCCCeEEEe-eccccc
630 Confidence 356789999999999999999999999999999999999987776 332222 3334 56778888653 444343
631
632
633 Q sp|P0DTC2|SPIK 179 LEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGW 258 (1273)
634 Q Consensus 179 legkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgw 258 (1273)
635 ... ..| .|.|++.||.|-+|..+...+ ..| +...++|...+.+- .+-|+..++ ++.+
636 T Consensus 180 ~~~--~~~----~f~F~~~dG~f~~Yyad~~~~------~~f-----~f~~~~~~~~~~yy---vip~~~~~~---~~~~ 236 (1299)
637 T 5I08_C 180 VSA--DWL----YFHFYQERGVFYAYYADVGMP------TTF-----LFSLYLGTILSHYY---VMPLTCNAI---SSNT 236 (1299)
638 T ss_dssp TTC--SEE----EEEEEEETTEEEEEEESSCSS------BEE-----EEEEECCSCCCEEE---ECCBCSTTS---SSSG
639 T ss_pred ccc--eee----EEEEEEeCCEEEEEEeccCCC------cce-----eecccceeecceee---eceeeccCC---CCCC
640 Confidence 322 111 299999999998875543222 111 11111232222222 333444444 5667
641
642
643 Q sp|P0DTC2|SPIK 259 TAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPF 338 (1273)
644 Q Consensus 259 tagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpf 338 (1273)
645 ....++|||++|.+|+|||+|+.||.|++||||+-|+++|-||..+||.+++|+|++|+||+||...++|.+.....|+|
646 T Consensus 237 ~~~~~~~~v~~L~~~~~Ll~fd~~G~It~AvDC~~~~~sEL~C~t~Sf~~~tGVY~lS~y~aqP~~~V~~~~~~~~~C~~ 316 (1299)
647 T 5I08_C 237 DNETLEYWVTPLSRRQYLLNFDEHGVITNAVDCSSSFLSEIQCKTQSFAPNTGVYDLSGFTVKPVATVYRRIPNLPDCDI 316 (1299)
648 T ss_dssp GGCCCCEEEEECEEEEEEEEECTTCCEEEEECGGGCHHHHHHHHHTSSSCCSCEEEEC--------CEEECCSSCCCCCH
649 T ss_pred CccceeEEEeecccceEEEEeCCCCeEeEEEecccCcchhheeeecccCCCCCeeecCCeEEEeeeEEEEecCCCCCCCH
650 Confidence 78889999999999999999999999999999999999999999999999999999999999999999999999899999
651
652
653 Q sp|P0DTC2|SPIK 339 GEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKI 418 (1273)
654 Q Consensus 339 gevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgki 418 (1273)
655 .+++++.++.++|.|.|+.++||..|+++|++..++++|+|||+||.||.+.||..|++|.|.|..+..++++||++|-|
656 T Consensus 317 ~~~~~~~~~P~p~~w~R~~f~nCnfn~s~Lls~~~~~~f~C~~ispskl~~mCfsSvtiD~Faip~s~~~~L~~g~~g~i 396 (1299)
657 T 5I08_C 317 DNWLNNVSVPSPLNWERRIFSNCNFNLSTLLRLVHVDSFSCNNLDKSKIFGSCFNSITVDKFAIPNRRRDDLQLGSSGFL 396 (1299)
658 T ss_dssp HHHHTCSEEECGGGCEEEEECSCEECHHHHHHTSEEEEEEEESSCHHHHHHCCCSCEEEEEEECCSTTGGGGSSSCCSSC
659 T ss_pred HHHhhCCCCCCccceEEeEEecCCCCHHHHHhhceeeeeeeeCCCHHHhcccccCeeEEEEEeccCcchHhcCCCCCcHh
660 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
661
662
663 Q sp|P0DTC2|SPIK 419 ADYNYKLPDDFTGCVIAWNSNNLDSKV----GGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCN------------- 481 (1273)
664 Q Consensus 419 adynyklpddftgcviawnsnnldskv----ggnynylyrlfrksnlkpferdisteiyqagstpcn------------- 481 (1273)
665 ++||||+|++|+||+++|+-.+.+..+ -++||.-|+. +..++++.++..+..-..++++-|.
666 T Consensus 397 ~~~NYkl~~~~~sC~l~~~~~~~~vt~t~~nps~~n~ry~~-~~~~~~~hdv~Ys~~cf~~~~~~cPC~~p~~~~~~~~~ 475 (1299)
667 T 5I08_C 397 QSSNYKIDISSSSCQLYYSLPLVNVTINNFNPSSWNRRYGF-GSFNLSSYDVVYSDHCFSVNSDFCPCADPSVVNSCAKS 475 (1299)
668 T ss_dssp CCCCCCCCCSSSEEEEEEEEESSSCEEECCCCSCCTTTCCC-CCCSSEEECCCSCCCCCTTCCCCCCC------------
669 T ss_pred HhccccCCCCCCceEEEEEcccccceecCCCcccchhccCc-cccCCCccceeeeccccccCCCCCCCCChhhcccCcCC
670 Confidence 999999999999999999966655444 3567766665 6667888888888777766655443
671
672
673 Q sp|P0DTC2|SPIK 482 --------------------------------GVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFEL------------ 517 (1273)
674 Q Consensus 482 --------------------------------gvegfncyfplqsygfqptngvgyqpyrvvvlsfel------------ 517 (1273)
675 +..+..|+-+...+.....-|+|++.+++.|++.+.
676 T Consensus 476 ~~~~~~~~~~t~~r~c~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~q~~~~vg~g~~c~g~~V~~~k~g~~~~~~~c~c~ 555 (1299)
677 T 5I08_C 476 KPPSAICPAGTKYRHCDLDTTLYVKNWCRCSCLPDPISTYSPNTCPQKKVVVGIGEHCPGLGINEEKCGTQLNHSSCFCS 555 (1299)
678 T ss_dssp --------------------------------------------------------------------------------
679 T ss_pred CCCCCCCCCCCcceecccccccccccccccccCCCCCCccCCCCCCCceeeeecccccCeeEEEeeecCCCCCCCCcccC
680 Confidence 111344554554444455679999999999999888
681
682
683 Q sp|P0DTC2|SPIK 518 ---------------------------LHAPATVCGP---KKSTNLVKNKCVNFNFNGLTGTGVLTE-SNKKFLPFQQFG 566 (1273)
684 Q Consensus 518 ---------------------------lhapatvcgp---kkstnlvknkcvnfnfngltgtgvlte-snkkflpfqqfg 566 (1273)
685 ...++|+|+. +.+++++.++||++|..|.||+||+++ ++..++.+|.+.
686 T Consensus 556 ~~af~gws~dsc~~~~~~~~~~~~~~~~~~t~Tvcp~~~~~~~snI~Ln~CVdYNIYG~TGtGVItnvt~s~~~~~qGL~ 635 (1299)
687 T 5I08_C 556 PDAFLGWSFDSCISNNRCNIFSNFIFNGINSGTTCSNDLLYSNTEISTGVCVNYDLYGITGQGIFKEVSAAYYNNWQNLL 635 (1299)
688 T ss_dssp ---CCSCCEEECCBTTEEEEEEEEEESSSSSSSCEECTTCCCCCCCCCSSSEEEEETTEEEEEEEEECCCCCCCTTTCEE
689 T ss_pred ccccccccccccccCCccccccceeccCCCCCCcCCCccccCCceeEeCeeEeEEeCCCeeEEEEEeCCCceeecCCcEE
690 Confidence 5668999998 467899999999999999999999999 444467788888
691
692
693 Q sp|P0DTC2|SPIK 567 RDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTR 646 (1273)
694 Q Consensus 567 rdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtr 646 (1273)
695 .|-+.-..++|++.++++..|+||..+.++++..|. +...+.+++.++|.++..... +....+-|+|.
696 T Consensus 636 ydssGdLlgFKn~ttg~iYsV~PC~~v~vqvVv~~~--~~vgall~~n~~cs~~~~n~~----------~~~~~~~~~t~ 703 (1299)
697 T 5I08_C 636 YDSNGNIIGFKDFLTNKTYTILPCYSGRVSAAFYQN--SSSPALLYRNLKCSYVLNNIS----------FISQPFYFDSY 703 (1299)
698 T ss_dssp EETTEEEEEEECTTTCCEEEEECCCCCCEEEECCCC-----CEEEEETCCHHHHHHTC----------------CCEECS
699 T ss_pred EeCCCCEEEEEeCCCCcEEEEEeCcccceEEEEeCC--CcceeEEeecCcccceeecee----------eecCccceecc
700 Confidence 888888889999999999999999999999998876 344689999999988765311 22222559999
701
702
703 Q sp|P0DTC2|SPIK 647 AGCLIGAEHVNN--SYECDIPIGAGICASYQTQTNSPRRARSVAS--QSIIAYTMSL-----GAENSVAYSNNSIAIPTN 717 (1273)
704 Q Consensus 647 agcligaehvnn--syecdipigagicasyqtqtnsprrarsvas--qsiiaytmsl-----gaensvaysnnsiaiptn 717 (1273)
705 .||.+++++... ..+|+.|.|.|+|+.+.+. +++++++..+ .++..| +.. -....+..+...|.||+|
706 T Consensus 704 ~gc~~~~~~~t~~~v~~c~~~~~~~~C~~~~~~--~~~g~~~~~~~~~~l~~~-~p~~~~~~~~~~~~~~~~~~IsIPtN 780 (1299)
707 T 5I08_C 704 LGCVLNAVNLTSYSVSSCDLRMGSGFCIDYALP--SSGGSGSGISSPYRFVTF-EPFNVSFVNDSVETVGGLFEIQIPTN 780 (1299)
708 T ss_dssp SEEESSCBCCCSSBCSSCSCBCSTTEEEEC----------------CCEEEEC-CCCC---------------------C
709 T ss_pred cceeeeceeccCCccccCccccCCceeeecCCC--CCCCCCCCcCCCeeeeEe-cceeeeecCCcccccceEEEEEccCC
710 Confidence 999999976644 7789999999999999877 5555554332 234443 221 011124445558999999
711
712
713 Q sp|P0DTC2|SPIK 718 FTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTP-P--- 793 (1273)
714 Q Consensus 718 ftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktp-p--- 793 (1273)
715 |||+|++|-++++|.|.+|||.+|+||++.+|.+||.|||+||..+++||.|.+..+|....+++..+++-++++ +
716 T Consensus 781 FTisv~~EyiQt~~~kVsVDCa~YVCngn~~C~~lL~qYgs~C~~i~~~l~~~~~~~~~~~~~~~~~~~~~~~~ss~~~~ 860 (1299)
717 T 5I08_C 781 FTIAGHEEFIQTSSPKVTIDCSAFVCSNYAACHDLLSEYGTFCDNINSILNEVNDLLDITQLQVANALMQGVTLSSNLNT 860 (1299)
718 T ss_dssp CCCCEEEECCCCCCCEEEECTTTTTCCSCTHHHHHHHHHCTTHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCCCCTTCCC
719 T ss_pred ceeEEEEEEeeccCCCeEEecceeecCCCHHHHHHHHHHHHHHHHHHHHHHHHHHhhcHHHHHHHHHHhccccccccccc
720 Confidence 999999999999999999999999999999999999999999999999999999999999999999999988775 3
721
722
723 Q sp|P0DTC2|SPIK 794 --IKDFGGFNFSQILPDPSK---PSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDE 868 (1273)
724 Q Consensus 794 --ikdfggfnfsqilpdpsk---pskrsfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltde 868 (1273)
725 +..+++|||+.+||.+.. +++||+||||||+||..+|.|+.+.|.+|.+...+|||+|||.|||+.||||++++|
726 T Consensus 861 ~~~~~~~~~N~s~ll~~~~~~~~~~~RS~IEDLLF~KV~t~glG~~~~Y~~Ct~g~~i~DL~CaQ~yNGi~VLP~v~d~~ 940 (1299)
727 T 5I08_C 861 NLHSDVDNIDFKSLLGCLGSQCGSSSRSLLEDLLFNKVKLSDVGFVEAYNNCTGGSEIRDLLCVQSFNGIKVLPPILSET 940 (1299)
728 T ss_dssp ----------------------------CHHHHGGGTSCCCHHHHHHHHHTTSSSCSCCTTHHHHHHSSEEEECCSSCHH
729 T ss_pred CcccCCCCccchhhcccccCCCCCCcccHHHHHhcCceEeCCCChhHHHHHccCCccHHHHhcccccCeEEEeCCCCCHH
730 Confidence 378899999999998763 479999999999999999999999999999999999999999999999999999999
731
732
733 Q sp|P0DTC2|SPIK 869 MIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKL 948 (1273)
734 Q Consensus 869 miaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgkl 948 (1273)
735 |+|.||++|++|....|||+ |..||||+||.||+||+|+||+||.||||+|||.||.||+.||+.+.++++||.|+
736 T Consensus 941 ~~amYTasL~g~m~~gg~T~----aaaIPFa~~vq~RlN~v~lt~~VL~~NQk~iA~sFN~A~~~iq~~f~~~~~Al~ki 1016 (1299)
737 T 5I08_C 941 QISGYTTAATVAAMFPPWSA----AAGVPFSLNVQYRINGLGVTMDVLNKNQKLIANAFNKALLSIQNGFTATNSALAKI 1016 (1299)
738 T ss_dssp HHHHHHHHHHHHHHCTTTCS----SSSSCHHHHHHHHHTTSSCSSSHHHHTTTHHHHHHHHHHHHHHGGGGSCCSHHHHH
739 T ss_pred HHHHHHHHHHHHhhccCchh----cccCchHHHHHHHhchhcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
740 Confidence 99999999999999999997 55689999999999999999999999999999999999999999999999999999
741
742
743 Q sp|P0DTC2|SPIK 949 QDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATK 1028 (1273)
744 Q Consensus 949 qdvvnqnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatk 1028 (1273)
745 |||||++++||++|++||+.|||||||.++||++|||++||++||||||+|||.+|++||+|||+|++|+|||+.||..|
746 T Consensus 1017 Q~VVN~~~~aL~~L~~qL~~nFgAISssI~dIy~RLD~leAdaQVDRLItGRL~aLnafVtQ~L~~~~evr~sr~LA~qK 1096 (1299)
747 T 5I08_C 1017 QSVVNANAQALNSLLQQLFNKFGAISSSLQEILSRLDNLEAQVQIDRLINGRLTALNAYVSQQLSDITLIKAGASRAIEK 1096 (1299)
748 T ss_dssp HHHHHHHHHHHHHHHHGGGCCSSSSSCSTHHHHHHCCSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
749 T ss_pred HHHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
750 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
751
752
753 Q sp|P0DTC2|SPIK 1029 MSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVSNGTHWFVTQR 1107 (1273)
754 Q Consensus 1029 msecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregvfvsngthwfvtqr 1107 (1273)
755 |.|||..||+|.+|||.|.|++|+||.||+|++|+|++|+|.+.++.+++|.+|+++ ++..|++|+|+.+...|++|.|
756 T Consensus 1097 INECVkSQS~R~gFCGnGtHi~Si~q~APnGi~FlH~~y~Pt~~~~V~a~~GlC~~~~~~~~~~~g~f~~~n~~~~~T~r 1176 (1299)
757 T 5I08_C 1097 VNECVKSQSPRINFCGNGNHILSLVQNAPYGLLFIHFSYKPTSFKTVLVSPGLCLSGDRGIAPKQGYFIKQNDSWMFTGS 1176 (1299)
758 T ss_dssp CCCCCTSCCSCSSSSCSSCCSEEEEEEETTEEEEEEEC------------------------------------------
759 T ss_pred HHHHHhcCCCCccccCCCeEEEeeeeccCCeEEEEEEEecCCeeeEEEEEeeEEecCCeeEEecCcEEEeeCCEEEEecc
760 Confidence 999999999999999999999999999999999999999999999999999999995 7999999999999999999999
761
762
763 Q sp|P0DTC2|SPIK 1108 NFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLN 1187 (1273)
764 Q Consensus 1108 nfyepqiittdntfvsgncdvvigivnntvydplqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrln 1187 (1273)
765 ++|||..||.+|...-..|||....+|+++..+..|++..|+|||+|+|||+++...|+.++..+|++++|++.||++|+
766 T Consensus 1177 ~~y~Pr~~t~~d~v~~~sC~v~y~n~~~~~~~~~~p~~~df~~el~~~~~n~~~~~p~~~~~~~~n~t~LNLt~EI~~Lq 1256 (1299)
767 T 5I08_C 1177 SYYYPEPISDKNVVFMNSCSVNFTKAPFIYLNNSIPNLSDFEAELSLWFKNHTSIAPNLTFNSHINATFLDLYYEMNVIQ 1256 (1299)
768 T ss_dssp --------------------------------------------------------------------------------
769 T ss_pred ccccCCCCCccCeEEeccceeEEEEcChhhCCCCCCCCCChHHHHHHHHhcCCCCCCCCCcccccccceechHHHHHHHH
770 Confidence 99999999999999999999999999999999999999999999999999999977888878899999999999999999
771
772
773 Q sp|P0DTC2|SPIK 1188 EVAKNLNESLIDLQELGKYEQYIKW-PWYIWLGFIAG 1223 (1273)
774 Q Consensus 1188 evaknlneslidlqelgkyeqyikw-pwyiwlgfiag 1223 (1273)
775 |+.|+||+++.+++.+.+.|.|+|| |||+||..+..
776 T Consensus 1257 evIknLN~S~~ilE~l~~~e~YVkwdpwwVwL~i~l~ 1293 (1299)
777 T 5I08_C 1257 ESIKSLNGSGYIPEAPRDGQAYVRKDGEWVLLSTFLG 1293 (1299)
778 T ss_dssp -------------------------------------
779 T ss_pred HHHHHHHhcCCCCCCCCCccceecccChhHHHHhhhh
780 Confidence 9999999999999999999999998 99999976543
781
782
783 No 5
784 >5X5F_B S protein; MERS-CoV, spike glycoprotein, prefusion, single; 4.2A {Middle East respiratory syndrome coronavirus}
785 Probab=100.00 E-value=6.1e-198 Score=1670.09 Aligned_cols=1163 Identities=31% Similarity=0.500 Sum_probs=888.5 Template_Neff=3.800
786
787 Q sp|P0DTC2|SPIK 14 QCVNL-TTRTQLPPAYT----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG--T-------KRF 79 (1273)
788 Q Consensus 14 qcvnl-ttrtqlppayt----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng--t-------krf 79 (1273)
789 .|... -...-+.+.++ -+-.+|+||||..++++..+-.|+||.+.-++.+-.- ++|++. + -.+
790 T Consensus 12 ~C~~~~~~~~~~~~~~~~~idvs~~~G~yYP~~rvysN~TlL~qglfP~~gs~~~~y~---~~~t~~~~~~~~~~~~~~y 88 (1323)
791 T 5X5F_B 12 ACIEVDIQQTFFDKTWPRPIDVSKADGIIYPQGRTYSNITITYQGLFPYQGDHGDMYV---YSAGHATGTTPQKLFVANY 88 (1323)
792 T ss_dssp BCCCEEECGGGTCCCCCCCCCGGGTTTCBCCSSCCBSSCEEEEEEEECCTTCCCEEEC---CEECCBCSSCBCSEEECSG
793 T ss_pred cceecccccccCCCCCCcceecccCceeEeeCCeeeeeeeeeeeceecCCCCcceEEE---EEecCCCCCCCcceeeecc
794 Confidence 36554 23333445555 3446899999999999999999999999988876532 333333 1 356
795
796
797 Q sp|P0DTC2|SPIK 80 DNPVLPFNDGVYFASTEKSNIIR-----------------GWIFGTTLDSKT---Q------SLLIVNNATNVVI----- 128 (1273)
798 Q Consensus 80 dnpvlpfndgvyfasteksniir-----------------gwifgttldskt---q------sllivnnatnvvi----- 128 (1273)
799 +.+..||+||+++...+..|--. .++||+|.+... + +++|+++-.+.++
800 T Consensus 89 ~~~~~~F~dGifvkv~~~~n~tg~~~~~~~~~~~~~~~ypa~~fGstF~Nts~~~~~~~~~~tlVI~P~~~g~~~~~~~~ 168 (1323)
801 T 5X5F_B 89 SQDVKQFANGFVVRIGAAANSTGTVIISPSTSATIRKIYPAFMLGSSVGNFSDGKMGRFFNHTLVLLPDGCGTLLRAFYC 168 (1323)
802 T ss_dssp GGCCEECTTCEEEEESTTTTSEEECSSSTTCEEEEECCCCCEEEESCEEECTTSCEEEECSEEEEEEEETTTTEEEEEEE
803 T ss_pred CCChhhccCeEEEEEeeeeccCCCeeeCCccccchhhhccceEeeccccCCCCCccccccceEEEEecCCCCchheeeee
804 Confidence 77899999999998877666422 256999998666 5 8889888876543
805
806
807 Q sp|P0DTC2|SPIK 129 --KVCEFQFCNDPFLGVYYHKNN---KSWMES---------EFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVF 194 (1273)
808 Q Consensus 129 --kvcefqfcndpflgvyyhknn---kswmes---------efrvyssannctfeyvsqpflmdlegkqgnfknlrefvf 194 (1273)
809 ...+..-|..|..-+++.-+. .+|..+ +++.|....+|+|.|. +.|-+|... ..|- |.|
810 T Consensus 169 ~~~prtit~C~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~nfT~d~~~--~wf~----~~F 241 (1323)
811 T 5X5F_B 169 ILEPRSGNHCPAGNSYTSFATYHTPATDCSDGNYNRNASLNSFKEYFNLRNCTFMYT-YNITEDEIL--EWFG----ITQ 241 (1323)
812 T ss_dssp EEEECCSBTSTTSTTCCCCCEEECHHHHSCTTCCCTTHHHHHHHHHEEEEEEEEEEE-EECCCCCCC--EEEE----EEE
813 T ss_pred cccccccCcCCCCCeEeeeeecCCCCccCCCCcccccccccchhHhcccCCceEEEe-eecCcchhh--heee----EEe
814 Confidence 322333455555555432221 345333 6778889999999875 344333211 1111 899
815
816
817 Q sp|P0DTC2|SPIK 195 KNID-GYFKIYSKHTPINL---VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYL 270 (1273)
818 Q Consensus 195 knid-gyfkiyskhtpinl---vrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgyl 270 (1273)
819 +..| |.|-+|.-++..+. ..-+| |+..+.+.. .+-|+..++ .+.+. ..++|||++|
820 T Consensus 242 ~~~~~G~f~~Y~~d~~~~~~f~f~~~~-~~~~~~yy~---------------v~p~~~~~~---~~~~~-~~~~~~v~~L 301 (1323)
821 T 5X5F_B 242 TAQGVHLFSSRYVDLYGGNMFQFATLP-VYDTIKYYS---------------IIPHSIRSI---QSDRK-AWAAFYVYKL 301 (1323)
822 T ss_dssp ETTEEEEEESTTTCTTTCCBEEEEEEC-CCSCCCEEE---------------ECCEEECCC---GGGCC-EECCEEEEEC
823 T ss_pred eecCceeEEEEEEeccCCcceeccccc-ceeccceee---------------eeeeeecCC---ccccc-eeEEEEEEEc
824 Confidence 9999 99999876654332 12222 444444443 233444444 45566 7889999999
825
826
827 Q sp|P0DTC2|SPIK 271 QPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASV 350 (1273)
828 Q Consensus 271 qprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasv 350 (1273)
829 .+|+|||+|++||.|++||||+-|+++|-||..+||.+++|+|++|+||+||....+|.++. ..|+|.++++ .++.++
830 T Consensus 302 ~~~~yLl~fd~nG~I~~avDC~~~~~seL~C~~~sf~~~tGVY~~S~y~aqp~~~v~~~~~~-~~C~~~~~~~-~~~P~p 379 (1323)
831 T 5X5F_B 302 QPLTFLLDFSVDGYIRRAIDCGFNDLSQLHCSYESFDVESGVYSVSSFEAKPSGSVVEQAEG-VECDFSPLLS-GTPPQV 379 (1323)
832 T ss_dssp EEEEEEEEECTTSCEEEEEETTSCHHHHHHHTTTCSCCCSSEECCCCCBBCCCSCEECC----CCCCCHHHHS-BCCCBG
833 T ss_pred cceeEEEeecCCCeEEEEEecCCCccchheeEeceecCCCCeeecCCEEEEeeeEEEEecCC-CCCCchHHhc-CCCCCc
834 Confidence 99999999999999999999999999999999999999999999999999999999999999 9999999999 889999
835
836
837 Q sp|P0DTC2|SPIK 351 YAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFT 430 (1273)
838 Q Consensus 351 yawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddft 430 (1273)
839 |.|.|+.++||..|+|+|++...+++|+||||+|.||.++||..|++|.|.|..+..++++||++|-|++||||+|+||+
840 T Consensus 380 ~~w~R~~f~nCnfN~s~Lls~~~~~sf~C~gIspskLa~mCfsSvtiD~Faip~s~~~~Lq~G~~G~i~~yNYKld~~~~ 459 (1323)
841 T 5X5F_B 380 YNFKRLVFTNCNYNLTKLLSLFSVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVSSAGPISQFNYKQSFSNP 459 (1323)
842 T ss_dssp GGCEEEEECSEEECHHHHHHHSEEEEEEEESSCHHHHHHSCCSCEEEEEEECCGGGGGGSCTTCCSHCCCCCCCCCSSSC
843 T ss_pred ceeEEeEEecCCCcHHHHHhhceeeeeeecCCCHHHHcccccceeeEEEEecCccccceecCCCCChhhhccccCCCCCC
844 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
845
846
847 Q sp|P0DTC2|SPIK 431 GCVIAWNSNNLDSKV--GGNYNYLYRLFRKSNLKPFERDISTEI---YQAGSTPCNGV-EGFNCYFPLQSY--------- 495 (1273)
848 Q Consensus 431 gcviawnsnnldskv--ggnynylyrlfrksnlkpferdistei---yqagstpcngv-egfncyfplqsy--------- 495 (1273)
849 ||+++|+-...+..+ -.+|+|+.|-+++.. ++. ++. ..+ .+-|+-. ...+|+.|...+
850 T Consensus 460 sC~l~y~~pa~~vn~t~p~~y~yi~~~~~~~~-----~~~-~~~~~~~~~-~~~cpc~~~~~~~~~~~~~~~~~~~~~~~ 532 (1323)
851 T 5X5F_B 460 TCLILATVPHNLTTITKPLKYSYINKCSRLLS-----DDR-TEVPQLVNA-NQYSPCVSIVPSTVWEDGDYYRKQLSPLE 532 (1323)
852 T ss_dssp EEEEEEECCSSCCSBCCCSEEEEEEEEEEECT-----TSS-CEEECCCCT-TSCCTTTTTSCSSCSSTTCEEEEECCTTT
853 T ss_pred ccEEEEEcCccccccCCCccceeeeeeeccCC-----CCC-Ccchhhccc-cccCCCCccCCccccCCCCcccccccccc
854 Confidence 999999955533322 445666555555433 222 222 111 1111100 012344443222
855
856
857 Q sp|P0DTC2|SPIK 496 --GFQP----TNGVGYQPYRVVVLSFELLHAPATVCGP-----KKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQ 564 (1273)
858 Q Consensus 496 --gfqp----tngvgyqpyrvvvlsfellhapatvcgp-----kkstnlvknkcvnfnfngltgtgvltesnkkflpfqq 564 (1273)
859 |..+ ..++++|++.++|++++..+.++|||++ |.+|.++.++||++|+.|+||+||++|++..+..+|.
860 T Consensus 533 ~~~~~~~~~~~~~~~~~~~g~~Vis~k~~~~s~tVCp~~~d~~~~~T~~~l~vCV~YnlYGiTGtGVf~~sn~~~~~~Q~ 612 (1323)
861 T 5X5F_B 533 GGGWLVASGSTVAMTEQLQMGFGITVQYGTDTNSVCPKLEFANDTKIASQLGNCVEYSLYGVSGRGVFQNCTAVGVRQQR 612 (1323)
862 T ss_dssp TSSEEEEEEEEEECCSSCEEEEEEECCCCSSCCCEEECC------CCSSSCCCSSCEECSSCCCCCCCEECCCCSCSSSC
863 T ss_pred CCchhcccccccccccceeEEEEEEeEcCCCccccCCCcccCCcCCcchhcCceeeEEecceeeeEEEEecCccccccee
864 Confidence 2233 4589999999999999999999999988 5668999999999999999999999999999999999
865
866
867 Q sp|P0DTC2|SPIK 565 FGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRV--YSTGSNV 642 (1273)
868 Q Consensus 565 fgrdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrv--ystgsnv 642 (1273)
869 |..|-.+-..+.|| +++++.+|+||..|+|||+++++ ++..|+||++++|.+|...+|..+.+|.|+. ++...+.
870 T Consensus 613 f~yds~Gnl~gfk~-~tg~vY~I~PC~s~~VSViy~~~--s~e~AlLf~~v~C~~v~t~~~~~~~~~~~~~~~~~~~~~~ 689 (1323)
871 T 5X5F_B 613 FVYDAYQNLVGYYS-DDGNYYCLRACVSVPVSVIYDKE--TKTHATLFGSVACEHISSTMSQYSRSTRSMLKRRDSTYGP 689 (1323)
872 T ss_dssp CCBCSSSCBCCCCC-SSSCCEECCCCCBCCCBEECCTT--TTCCCCBCSSCCTTTCCTTCTTBSCSSSSCCC--------
873 T ss_pred EEEcCCCCEEEEEe-CCCCEEEEeeceeeceeEEEeCC--CCceEEEeCCccccceecceeeecCCCchhcccccCCCCC
874 Confidence 99999999999999 99999999999999999999998 7799999999999999999999999999998 7778889
875
876
877 Q sp|P0DTC2|SPIK 643 FQTRAGCLIGAEHVNN-SYECDIPIGAGICASYQTQTNS-PRRARSVAS-QSII--AYTMSLGAENSVAYSNNSIAIPTN 717 (1273)
878 Q Consensus 643 fqtragcligaehvnn-syecdipigagicasyqtqtns-prrarsvas-qsii--aytmslgaensvaysnnsiaiptn 717 (1273)
879 |||-+||++||++.+. .+|||+|+|+|+|+.|.+...+ +|+.|++.. ..+. +|+|.+-. .++.+++..|.||+|
880 T Consensus 690 fdT~~GCVvnA~n~t~~V~~C~lplG~glC~~y~~~s~~~~r~~~~~~~~~~l~~~~y~~p~~~-~~~~~~~~~i~IP~n 768 (1323)
881 T 5X5F_B 690 LQTPVGCVLGLVNSSLFVEDCKLPLGQSLCALPDTPSTLTPRSVSSVPGEMRLASIAFNHPIQV-DQLNSSYFKLSIPTN 768 (1323)
882 T ss_dssp ---CBCCSSSCBSSCCCCCCCCCCCTTCCSSSCCCCCC------------CCCCCCCCCCCCCC-CCCCSSCCEEEECCC
883 T ss_pred CCCccceeeecccCCCceeeCCCCCCcceecCCCCcCcCccccccCCCCceEEEEEeecCCeee-cccCCCCeeEEcccc
884 Confidence 9999999999999988 8999999999999999988755 344444443 3344 67777765 778889999999999
885
886
887 Q sp|P0DTC2|SPIK 718 FTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDF 797 (1273)
888 Q Consensus 718 ftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdf 797 (1273)
889 |||+|++|-+.++|.|.+|||.+|+||++.+|.+||.|||+||..+|+||.|.+.++|.+..+++..+++-++.+-+..|
890 T Consensus 769 Ft~~v~~EyiQ~~~~kv~iDC~~YVC~~~~~C~~lL~qYgs~C~~I~~aL~~~~~~~d~~~~~~~~~~~~~~~~~~~~~f 848 (1323)
891 T 5X5F_B 769 FSFGVTQEYIQTTIQKVTVDCKQYVCNGFQKCEQLLREYGQFCSKINQALHGANLRQDDSVRNLFASVKSSQSSPIIPGF 848 (1323)
892 T ss_dssp CCCCCCCCBCCCCCCCCEECTTSSSSSSCHHHHHHHHTSHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCSSCCCCCCSCC
893 T ss_pred eEEEEEEEEEeecCCceEEechhhccCCCHHHHHHHHHHHHHHHHHHHHHHHHhhhccHHHHHHHHhccccccCCCcCCC
894 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999998888887
895
896
897 Q sp|P0DTC2|SPIK 798 -GGFNFSQILPDPS---KPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDI--AARDLICAQKFNGLTVLPPLLTDEMIA 871 (1273)
898 Q Consensus 798 -ggfnfsqilpdps---kpskrsfiedllfnkvtladagfikqygdclgdi--aardlicaqkfngltvlpplltdemia 871 (1273)
899 |+|||+.+||.+. ++++||+||||||+||.+.|.||.+.|+.|.... ..|||+|||.+||+.||||..++||.+
900 T Consensus 849 ~~~~N~s~ll~~~~~~~~~~~RS~iEDLLF~KV~t~g~G~~~~Y~~C~~g~~~~i~DL~CAQ~yNGi~VLP~v~~~~le~ 928 (1323)
901 T 5X5F_B 849 GGDFNLTLLEPVSISTGSRSARSAIEDLLFDKVTIADPGYMQGYDDCMQQGPASARDLICAQYVAGYKVLPPLMDVNMEA 928 (1323)
902 T ss_dssp BTTBCCTTSCCC--------CCCHHHHHHHHSSCCCCCCSSSHHHHHHTC--------CCTTTSCSEECCCCSSCHHHHH
903 T ss_pred CCCcccceeccCCCCCCCccceeHHHHHhcceeeeCCCCcccChhhhcccCCccHHHHhheeEeCCEeecCCcCCHhHHH
904 Confidence 5799999999876 3468999999999999999999999999999554 899999999999999999999999999
905
906
907 Q sp|P0DTC2|SPIK 872 QYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDV 951 (1273)
908 Q Consensus 872 qytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdv 951 (1273)
909 +|+.+++.+....||++|..++..|||++++.+|+|++++++++|.+|||.|||.||.|||.||+.+.++++||.|+|++
910 T Consensus 929 ~yt~SdvG~l~~~r~e~G~tsaaaIpfs~~Vy~RLN~l~~~~~vL~~nq~~Ia~sFN~aIg~iq~gf~t~~~Al~kIq~v 1008 (1323)
911 T 5X5F_B 929 AYTSSLLGSIAGVGWTAGLSSFAAIPFAQSIFYRLNGVGITQQVLSENQKLIANKFNQALGAMQTGFTTTNEAFQKVQDA 1008 (1323)
912 T ss_dssp HHHHHHHHHHHHHTTCSCCC-CCCCCHHHHHHHHHHHSSCCCHHHHHTTCCSHHHHHHHHHHHHHCCTTTCTTHHHHHHH
913 T ss_pred HHHHHHHHhhhcccccccCCccccCCchHHHHHHHHhhhchHHHHHHHHHHHHHHHHHHHHHHhhccccHHHHHHHHHHH
914 Confidence 99999999888889999999999999999999999999999999999999999999999999999999999999999999
915
916
917 Q sp|P0DTC2|SPIK 952 VNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSE 1031 (1273)
918 Q Consensus 952 vnqnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmse 1031 (1273)
919 ||+++++|++|..||+.|||||||.+++|+.|||++||++|+||||+|||.+|.+||+|||+|++|+|+|+.||..|+.|
920 T Consensus 1009 VN~~~~als~L~~qLn~~FgAISssi~gI~~RLd~lEa~iqvdrlInGRL~aLn~~Vtq~l~~~~~v~~sr~LA~qKiNE 1088 (1323)
921 T 5X5F_B 1009 VNNNAQALSKLASELSNTFGAISASIGDIIQRLDVLEQDAQIDRLINGRLTTLNAFVAQQLVRSESAALSAQLAKDKVNE 1088 (1323)
922 T ss_dssp HHHHHCCCCCHHHHHSSSCSSSCSSSTTTTTSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
923 T ss_pred HHHHHHHHHHHHHHHhhhcccchhcHhHHHHHHHHHHHHhCCChhhhcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
924 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
925
926
927 Q sp|P0DTC2|SPIK 1032 CVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHD---GKAHFPREGVFVSNG-----THWF 1103 (1273)
928 Q Consensus 1032 cvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichd---gkahfpregvfvsng-----thwf 1103 (1273)
929 ||..||+|.+|||.|.|++|+||.||+|++|+|.+|+|.+.++.+++|.+|++ +++..|+.|.|+.+. .+|+
930 T Consensus 1089 CVKSQS~R~gFCGnG~Hi~S~~q~AP~Gi~F~H~~~~Pt~~~~v~a~~GlC~~~~~~~~~~~~~g~~~~~~~~~~~~~~~ 1168 (1323)
931 T 5X5F_B 1089 CVKAQSKRSGFCGQGTHIVSFVVNAPNGLYFMHVGYYPSNHIEVVSAYGLCDAANPTNCIAPVNGYFIKTNNTRIVDEWS 1168 (1323)
932 T ss_dssp CCCSCCSSSTTSCSSSEEECCBCCCSSSCBBCCEECCCCCCEEEECCSCCCCSSCCCCCCSSSCCCCSSSSCCCCSSSCC
933 T ss_pred HHHhcccccCCCCCCeeeEEeeeccCCeEEEEEEEecccceeEEEEEEEEeecCCCCceeeccCeEEEEeCCceeeceEE
934 Confidence 99999999999999999999999999999999999999999999999999996 688999999999876 5699
935
936
937 Q sp|P0DTC2|SPIK 1104 VTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPL--QPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQK 1181 (1273)
938 Q Consensus 1104 vtqrnfyepqiittdntfvsgncdvvigivnntvydpl--qpeldsfkeeldkyfknhtspdvdlgdisginasvvniqk 1181 (1273)
939 +|.|++|+|..||.+|+. --.|+|...-+|+++..|+ +|+...|+|||+|+|||+++...|+.++..+|+++.|++.
940 T Consensus 1169 ~T~r~~y~P~~~t~~~v~-i~sc~V~y~n~~~~~l~~~v~~p~yiDfn~el~~~~~n~~~~~p~l~~l~~fN~T~LNLt~ 1247 (1323)
941 T 5X5F_B 1169 YTGSSFYAPEPITSLNTK-YVAPQVTYQNISTNLPPPLLGNSTGIDFQDELDEFFKNVSTSIPNFGSLTQINTTLLDLTY 1247 (1323)
942 T ss_dssp CCCCSSSCCCCCCCSSTT-SCC----------------------------------------------------------
943 T ss_pred EeCCccccCccCCCCCEE-EECCcceEEecCCCCCCCccCCCCCCChHHHHHHHHhcCCCCCCCCCchhcceecccchHH
944 Confidence 999999999999999955 5778999999999999984 6899999999999999999988888889999999999999
945
946
947 Q sp|P0DTC2|SPIK 1182 EIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGF 1220 (1273)
948 Q Consensus 1182 eidrlnevaknlneslidlqelgkyeqyikwpwyiwlgf 1220 (1273)
949 ||++|+|+.|+||+++|||++|++||+|||||||+--|-
950 T Consensus 1248 EI~~Lq~~i~~LN~s~idLe~Ln~~e~YiKW~~~~~~~~ 1286 (1323)
951 T 5X5F_B 1248 EMLSLQQVVKALNESYIDLKELGNYTYYNKEFRLVPRGS 1286 (1323)
952 T ss_dssp ---------------------------------------
953 T ss_pred HHHHHHHHHHHHHhccCCHHHhCceeeeEeeeeecCCCC
954 Confidence 999999999999999999999999999999999987653
955
956
957 No 6
958 >6VSJ_A Spike glycoprotein, Carcinoembryonic antigen-related cell; MHV spike, CEACAM1a, Complex, Glycoprotein; HET: NAG; 3.94A {Murine coronavirus (strain A59)}
959 Probab=100.00 E-value=2.1e-195 Score=1649.54 Aligned_cols=1145 Identities=30% Similarity=0.512 Sum_probs=889.4 Template_Neff=4.000
960
961 Q sp|P0DTC2|SPIK 9 PLVSSQCVNLTTRTQLP---PAYT-----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAI--HVSGTNGTKR 78 (1273)
962 Q Consensus 9 plvssqcvnlttrtqlp---payt-----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhai--hvsgtngtkr 78 (1273)
963 ++....|...-...-++ |.++ -+-.+|+||||..++|+..+-.|+||.+.-++.+-+-.- |... .--.
964 T Consensus 22 ~i~~~~C~~~~~~~~~~~~~~~~s~~~idvs~~~G~yYPd~rvysN~TlL~qGLFP~~gs~~~~Y~~sgt~~~s--~~~~ 99 (1275)
965 T 6VSJ_A 22 YIGDFRCIQLVNSNGANVSAPSISTETVEVSQGLGTYYVLDRVYLNATLLLTGYYPVDGSKFRNLALRGTNSVS--LSWF 99 (1275)
966 T ss_dssp CCSSBCCCCCSEECCCCCCCCCCCSCBCCCTTSTTCBCCTTCBCCSCCCEEEEEEECTTCBCCBCCCEESSEEC--GGGS
967 T ss_pred cccCcceeEeecCCCCCCCCCCCcceeeeeecceeEEEeCCeEEeceeeeeccccCCCCCceeeEEeeccCCCC--cccc
968 Confidence 34555677653333333 3444 345689999999999999999999999998887654222 2222 1346
969
970
971 Q sp|P0DTC2|SPIK 79 FDNPVLPFNDGVYFASTEKSNI--------IRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNK 150 (1273)
972 Q Consensus 79 fdnpvlpfndgvyfasteksni--------irgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyhknnk 150 (1273)
973 +++++.||+||+++...+.+|- -..++||+|.+..+++++|+++-+...|.+|.|..|..|...+++.-+|.
974 T Consensus 100 y~~~~~~F~dGIfVkV~~~kn~t~~~~~~~ypa~~fGSTF~Nts~tvVI~P~~~~r~itvCq~~vC~~p~~~~~p~~g~~ 179 (1275)
975 T 6VSJ_A 100 QPPYLNQFNDGIFAKVQNLKTSTPSGATAYFPTIVIGSLFGYTSYTVVIEPYNGVIMASVCQYTICQLPYTDCKPNTNGN 179 (1275)
976 T ss_dssp STTTSCCCSSCEEEEEECCGGGSCTTCCCSSCCEEEESSCSTTSCEEEECEETTEECCEEECCCBBSSCCEESSCCCSSC
977 T ss_pred cCCcccccCCcEEEEeeeeccCCCCcchhccceeEEecccCCCceEEEEeCCCceeEeEEEEEEEcCCCeeEEccCCCCC
978 Confidence 7788999999999998887765 35678999999999999999999999999999999999999888744332
979
980
981 Q sp|P0DTC2|SPIK 151 SWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINL---VRDLPQGFSALEPLV 227 (1273)
982 Q Consensus 151 swmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknidgyfkiyskhtpinl---vrdlpqgfsaleplv 227 (1273)
983 +..+ ++. ....+|+|.|. +.|-+|... ..|- |.|+..||.|-+|..+...+. ..-+| |...+.+.
984 T Consensus 180 ~~~~--~~~-~d~~nc~f~~~-~nfT~d~~~--~~~~----~~F~~~dG~fy~Yyad~~~~~~f~f~~~~-~~~~~~yy- 247 (1275)
985 T 6VSJ_A 180 KLIG--FWH-TDVKPPICVLK-RNFTLNVNA--DAFY----FHFYQHGGTFYAYYADKPSATTFLFSVYI-GDILTQYY- 247 (1275)
986 T ss_dssp TTCC--SSB-CCCSCCCEEEE-CCEECCTTC--SEEE----EEBCEETTEECCEECSSSSCBEECCCCCC-SSCCCEEE-
987 T ss_pred ceee--ece-ecCCCCEEEEe-eeeccCccc--ceee----EEEEEcCCeEEEEEECCCcCcceeecccc-cceeceeE-
988 Confidence 3322 233 67889999764 455444322 1221 999999999988876644332 11222 33333333
989
990
991 Q sp|P0DTC2|SPIK 228 DLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFT 307 (1273)
992 Q Consensus 228 dlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlksft 307 (1273)
993 .+-|+..++ .+.+ ..++|||++|.+|+|||+|++||.||+||||+-|+++|-||..+||.
994 T Consensus 248 ---------------v~~~~~~~~---~~~~--~~~~~~v~~L~~~~~ll~fd~~G~i~~avDC~~~~~~el~C~~~sf~ 307 (1275)
995 T 6VSJ_A 248 ---------------VLPFICNPT---AGST--FAPRYWVTPLVKRQYLFNFNQKGVITSAVDCASSYTSEIKCKTQSML 307 (1275)
996 T ss_dssp ---------------ECCEECCCS---SCSC--CCCEEEEEEEEEEEEECCBCSSSCBCCCBCTTSCHHHHHHHHHTSSS
997 T ss_pred ---------------EeeeeecCC---CCCC--cccEEEEEeccceeEEEEecCCCeEeEEEecccCccceeeeEecccc
998 Confidence 233444333 2223 67899999999999999999999999999999999999999999999
999
1000
1001 Q sp|P0DTC2|SPIK 308 VEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKL 387 (1273)
1002 Q Consensus 308 vekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptkl 387 (1273)
1003 +++|+|++|+||+||....+|.++.+..|+|.++++|.++.++|.|.|+.++||..|+++|++..++++|+||||+|.||
1004 T Consensus 308 ~~~GVY~~s~y~a~p~~~v~~~~~~~~~C~~~~~~~~~~~P~p~~w~R~~~~nCnfn~s~Ll~~~~~~~f~C~~ispskl 387 (1275)
1005 T 6VSJ_A 308 PSTGVYELSGYTVQPVGVVYRRVANLPACNIEEWLTARSVPSPLNWERKTFQNCNFNLSSLLRYVQAESLFCNNIDASKV 387 (1275)
1006 T ss_dssp CCSSCEECCCCCCCCCCCCCCCCCCCCBCCTHHHHTCSEEECTTSCEEEEECSCBCCHHHHHHHSEEEECCBSSCCTTTS
1007 T ss_pred CCCceeecCCeEEEeeeEEEEecCCCCCCCHHHHHhcCCCCCchhcEEeEEecCCCCHHHHHhheeeccceecCCCHHHH
1008 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
1009
1010
1011 Q sp|P0DTC2|SPIK 388 NDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSK----VGGNYNYLYRLFRKSNLKP 463 (1273)
1012 Q Consensus 388 ndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldsk----vggnynylyrlfrksnlkp 463 (1273)
1013 .++||..|++|.|.|..+..++++||++|-|++||||+|+||+||+++|+-...+.. --++||+-|+.-++..++|
1014 T Consensus 388 ~~~CfssvtiD~F~ip~~~~~~l~~g~~g~i~~yNYkl~~~~~~C~l~~~~~~~~~~~t~~np~~~~~~~~~~~~~~f~~ 467 (1275)
1015 T 6VSJ_A 388 YGRCFGSISVDKFAVPRSRQVDLQLGNSGFLQTANYKIDTAATSCQLHYTLPKNNVTINNHNPSSWNRRYGFNDAGVFGK 467 (1275)
1016 T ss_dssp TTCCBSEEEEEEECCCSTTGGGGSTTCCSSHHHHTCCCCSSSCEEECEEEECTTTCEEECCCCCHHHHHHSCCTTTTTTT
1017 T ss_pred cccccCeeEEEEEeccchhceeecCCCCcHhHhccccCCCCCCceEEEEEcCcccccccCCCCccchhcccccccccccC
1018 Confidence 999999999999999999999999999999999999999999999999996543322 2357888888888899999
1019
1020
1021 Q sp|P0DTC2|SPIK 464 FERDISTEIY--QAGSTPCNG--V------------------EGFNCYF------------PLQSYGFQPTNGVGYQPY- 508 (1273)
1022 Q Consensus 464 ferdisteiy--qagstpcng--v------------------egfncyf------------plqsygfqptngvgyqpy- 508 (1273)
1023 +++|..-..+ ..+.+-|+. . .|..|+- |..+---+|+..+||+++
1024 T Consensus 468 ~~~dvvy~~~~~~~~~~~cpC~~~~~~~~ct~~~~~~~~~~~~~~~c~g~~vi~~~~g~~~~~~~c~c~~~af~gws~d~ 547 (1275)
1025 T 6VSJ_A 468 NQHDVVYAQQCFTVRSSFCPCAQPDIVSPCTTQTKPKSAFVNVGDHCEGLGVLEDNCGNADPHKGCICANNSFIGWSHDT 547 (1275)
1026 T ss_dssp CSSEEEEESCBBCCCSCCCSCC-----------CCCCBCCCCTTCCCCCBEECTTSEECCCSSSSCEECTTCEESEEEEE
1027 T ss_pred cccceeeccccccCCCCCCCCCCCCcCCCCCCCCCCccceeccccccceeEEeeccCCCCCCCCCccccCCcccccCccc
1028 Confidence 9999876533 233333330 0 1112211 001111256777888888
1029
1030
1031 Q sp|P0DTC2|SPIK 509 -----RVVVLSFELLHA--PATVCGP---KKSTNLVKNKCVNFNFNGLTGTGVLTESN-KKFLPFQQFGRDIADTTDAVR 577 (1273)
1032 Q Consensus 509 -----rvvvlsfellha--patvcgp---kkstnlvknkcvnfnfngltgtgvltesn-kkflpfqqfgrdiadttdavr 577 (1273)
1033 |++|+|++||++ ++|||+. +..++++.++||++|..|.||+||+++.+ ..+-.+|.+..+.+.-..++|
1034 T Consensus 548 c~~~~r~~i~~~~~ln~~~s~tvCp~~~~~~~t~I~ln~CVdYNIYGitGtGVItnvt~~~~~~~qgL~yS~sG~L~~FK 627 (1275)
1035 T 6VSJ_A 548 CLVNDRCQIFANILLNGINSGTTCSTDLQLPNTEVVTGICVKYDLYGITGQGVFKEVKADYYNSWQTLLYDVNGNLNGFR 627 (1275)
1036 T ss_dssp CEETTEEEEEEEEEEESTTCCSBBCSSSCCCCCCCCCSSCEEEEETTEEEEEEEECCCCCCCCSSCCCEECTTSCEEEEE
1037 T ss_pred cccCCceeeeeeeeccCCCCCCCCCCcCCCCCceEEeCeEEEEEeCCCeeEEEEEecCCcccccCccEEEeCCCCEEEEE
1038 Confidence 999999999998 8999998 34689999999999999999999999944 444466778888889999999
1039
1040
1041 Q sp|P0DTC2|SPIK 578 DPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVN 657 (1273)
1042 Q Consensus 578 dpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvn 657 (1273)
1043 ++.++++..|+||..+.++++..|. +...|+++..++|+++....+....+| .+.|+|-.||+++++|.+
1044 T Consensus 628 n~ttg~~YsV~PC~~v~qQvVV~~~--sivgalls~n~~cs~~~~n~~~~~~~~--------~~~~~t~~gCv~~a~~~t 697 (1275)
1045 T 6VSJ_A 628 DLTTNKTYTIRSCYSGRVSAAFHKD--APEPALLYRNINCSYVFSNNISREENP--------LNYFDSYLGCVVNADNRT 697 (1275)
1046 T ss_dssp CTTTCCEEEEECCCCCEEECCCCTT--CSSCCEEETTCCHHHHHHTTCCSSCCC--------SCCEECSSSEECSCSEEE
1047 T ss_pred cCCCCCEEEEEeCceeceeEEEeCC--CceeEEEEeccceeceeeccceeeeCC--------CcceeccccceeccccCC
1048 Confidence 9999999999999999999999876 567789999999999886444333333 344999999999999887
1049
1050
1051 Q sp|P0DTC2|SPIK 658 N--SYECDIPIGAGICASYQTQTNSPRRARSVASQ-SIIA---YT-MSLGAENSVAYSNNSIAIPTNFTISVTTEILPVS 730 (1273)
1052 Q Consensus 658 n--syecdipigagicasyqtqtnsprrarsvasq-siia---yt-mslgaensvaysnnsiaiptnftisvtteilpvs 730 (1273)
1053 + ..+|++|.|.|||+.+..-.-.+ |++..+ .+.. +. +..........+...|.||+||||+|++|-++++
1054 T Consensus 698 ~~~~~~c~~~~g~giC~dg~~~~~~~---~~~~~~~~~~~~~~~~~~~~~~s~~~~~~~~~i~IP~nFtlsv~~EyiQt~ 774 (1275)
1055 T 6VSJ_A 698 DEALPNCDLRMGAGLCVDYSKSRRAH---RSVSTGYRLTTFEPYTPMLVNDSVQSVDGLYEMQIPTNFTIGHHEEFIQTR 774 (1275)
1056 T ss_dssp EEEESSCSEEETTTEEEEECTTTCSS---SSSTTSEEEEEECSCCCCBCCCSCSSSCCBCSCCBCCCCEEECCEEECCCC
1057 T ss_pred CCcCCCCCCccceEEccCcccceecc---cccCCCceeecccCCcccccCCCCCccCcceEEEccCceEEEEEEEEeecC
1058 Confidence 5 68999999999999998833222 221111 1111 11 1111125566777899999999999999999999
1059
1060
1061 Q sp|P0DTC2|SPIK 731 MTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTP-P----I-KDFGGFNFSQ 804 (1273)
1062 Q Consensus 731 mtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktp-p----i-kdfggfnfsq 804 (1273)
1063 |.|.+|||.+|+||++.+|.+||.|||+||..+|+||.|.+..+|....++++.+++.++.+ + | ...|+|||+.
1064 T Consensus 775 ~~kVsIDCa~YVC~g~~rC~~LL~QYgsfC~~I~~aL~~~~~~~d~~~~~~~~~~~~~~~~s~~~~~~~~~~~~~fN~s~ 854 (1275)
1065 T 6VSJ_A 775 SPKVTIDCAAFVCGDNTACRQQLVEYGSFCVNVNAILNEVNNLLDNMQLQVASALMQGVTISSRLPDGISGPIDDINFSP 854 (1275)
1066 T ss_dssp CCEEECCHHHHHSCSSHHHHHHHGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCCCCBCC----------------
1067 T ss_pred CCCeEEEhhheecCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhccccccccCCCCCCCCCCCccchh
1068 Confidence 99999999999999999999999999999999999999999999999999999999998875 2 2 4456799999
1069
1070
1071 Q sp|P0DTC2|SPIK 805 ILPD-----------PSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQY 873 (1273)
1072 Q Consensus 805 ilpd-----------pskpskrsfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdemiaqy 873 (1273)
1073 +||. |+++++||+|||||||||+.+|.|+.+.|.+|.+...+|||+|||.|||+.||||++++||+|.|
1074 T Consensus 855 ll~~~~~~~~~~~~~~~~~~~RSaIEDLLF~KV~t~glG~~~~Yk~Ct~g~~i~DL~CAQyyNGImVLPpvvd~~~~amY 934 (1275)
1075 T 6VSJ_A 855 LLGCIGSTCAEDGNGPSAIRGRSAIEDLLFDKVKLSDVGFVEAYNNCTGGQEVRDLLCVQSFNGIKVLPPVLSESQISGY 934 (1275)
1076 T ss_dssp ------CCSSCCSSSTTTTTTTTHHHHHHHHHCSSCTTHHHHHHHHHHTTSSTTSSHHHHHHTTCEEECCSSCHHHHHHH
1077 T ss_pred hcccccCCcccCCCCCCccCcccHHHHHHcceeeecCCchHHHHHhccCCcchHHhhcccccCcEEEeCCCCCHHHHHHH
1078 Confidence 9986 56668999999999999999999999999999999999999999999999999999999999999
1079
1080
1081 Q sp|P0DTC2|SPIK 874 TSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVN 953 (1273)
1082 Q Consensus 874 tsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvn 953 (1273)
1083 |++|++|....|||+ |..||||+||.||+||+|+||+||.||||+|||.||.||+.||+.++++++||.|+|||||
1084 T Consensus 935 TasL~g~m~~gg~Ta----aaaIPFa~~vq~RlN~v~lt~~VL~~NQk~iA~sFN~A~~~iq~~f~~~~~Al~kiQ~VVN 1010 (1275)
1085 T 6VSJ_A 935 TTGATAAAMFPPWSA----AAGVPFSLSVQYRINGLGVTMNVLSENQKMIASAFNNALGAIQDGFDATNSALGKIQSVVN 1010 (1275)
1086 T ss_dssp HHHHHHTTSCSSSCS----STTCCHHHHHHHHGGGTSCHHHHTTHHHHHHHHHHHHHHHHHHHHHSSCCHHHHHHHHHHH
1087 T ss_pred HHHHHHHhhcccchh----cccCchHHHHHHHhcccccchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
1088 Confidence 999999999999997 5568999999999999999999999999999999999999999999999999999999999
1089
1090
1091 Q sp|P0DTC2|SPIK 954 QNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECV 1033 (1273)
1092 Q Consensus 954 qnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecv 1033 (1273)
1093 ++++||++|++||+.|||||||.++||++|||++||++||||||+|||.+|++||+|||+|++|+|||+.||..||.|||
1094 T Consensus 1011 ~q~~aL~~L~~qL~~nFgAISssI~dIy~RLD~leAdaQVDRLItGRL~aLnafVtQ~L~~~~evr~sr~LA~qKINECV 1090 (1275)
1095 T 6VSJ_A 1011 ANAEALNNLLNQLSNRFGAISASLQEILTRLEAVEAKAQIDRLINGRLTALNAYISKQLSDSTLIKVSAAQAIEKVNECV 1090 (1275)
1096 T ss_dssp HHHHHHHHHHHGGGSCCSSSCSCHHHHHHHSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
1097 T ss_pred HHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
1098 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
1099
1100
1101 Q sp|P0DTC2|SPIK 1034 LGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVSNGTHWFVTQRNFYEP 1112 (1273)
1102 Q Consensus 1034 lgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregvfvsngthwfvtqrnfyep 1112 (1273)
1103 ..||+|.+|||.|.|++|+||.||+|++|+|++|+|.+.++.+++|.+|+++ ++..|+.|+|+.+...|++|.|++|||
1104 T Consensus 1091 KSQS~R~gFCGnGtHi~Si~q~APnGi~FlH~~y~Pt~~~~V~a~~GlC~~~~~~~~p~~g~fv~~n~~~~iT~r~~Y~P 1170 (1275)
1105 T 6VSJ_A 1091 KSQTTRINFCGNGNHILSLVQNAPYGLYFIHFSYVPISFTTANVSPGLCISGDRGLAPKAGYFVQDDGEWKFTGSSYYYP 1170 (1275)
1106 T ss_dssp CSCCSSSSCSSSSCCCCCCEECCTTSCEEECCEEECCSCCCCBCCTTCCSCCCSSSCCCCSCCCBCSSSSBCCCSSBCCC
1107 T ss_pred hcCCCcccccCCCeEEEEeeeccCCeEEEEEEEecccceEEEEEEeeeEecCCceEEecCeEEEecCCEEEEeccCcccC
1108 Confidence 9999999999999999999999999999999999999999999999999994 899999999999988999999999999
1109
1110
1111 Q sp|P0DTC2|SPIK 1113 QIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLG-DISGINASVVN----IQKEIDRLN 1187 (1273)
1112 Q Consensus 1113 qiittdntfvsgncdvvigivnntvydplqpeldsfkeeldkyfknhtspdvdlg-disginasvvn----iqkeidrln 1187 (1273)
1113 ..||.+|...-..|||...-+|+++..|..|++..|+|||+|+|||+++...|++ |++.+|+++++ ++.++++|+
1114 T Consensus 1171 r~it~~d~v~~~sC~v~y~n~~~~~l~~~~p~~~df~~el~~~~~n~~~~~p~~~~~~~~~N~t~L~Ei~~l~~~~~~l~ 1250 (1275)
1115 T 6VSJ_A 1171 EPITDKNSVIMSSCAVNYTKAPEVFLNTSIPNPPDFKEELDKWFKNQTSIAPDLSLDFEKLNVTLIKRMKQIEDKIEEIE 1250 (1275)
1116 T ss_dssp CSSCCC--------------------------------------------------------------------------
1117 T ss_pred CCCCccceEEeeccccEEEEcccccCCCCCCCCCChHHHHHHHHhcCCCCCCCcCCCHHHccHHHHHHHHHHHHHHHHHH
1118 Confidence 9999999999999999999999999999999999999999999999999666664 38899999986 666666666
1119
1120
1121 Q sp|P0DTC2|SPIK 1188 EVAKNLNESLIDLQELG 1204 (1273)
1122 Q Consensus 1188 evaknlneslidlqelg 1204 (1273)
1123 ++.++||.++.++..+.
1124 T Consensus 1251 ~~i~~in~~~~~~~~~~ 1267 (1275)
1125 T 6VSJ_A 1251 SKQKKIENEIARIKKIK 1267 (1275)
1126 T ss_dssp -----------------
1127 T ss_pred HHHHHHHHHHHHHHHhc
1128 Confidence 66777777766665543
1129
1130
1131 No 7
1132 >6VSJ_C Spike glycoprotein, Carcinoembryonic antigen-related cell; MHV spike, CEACAM1a, Complex, Glycoprotein; HET: NAG; 3.94A {Murine coronavirus (strain A59)}
1133 Probab=100.00 E-value=2.1e-195 Score=1649.54 Aligned_cols=1145 Identities=30% Similarity=0.512 Sum_probs=889.4 Template_Neff=4.000
1134
1135 Q sp|P0DTC2|SPIK 9 PLVSSQCVNLTTRTQLP---PAYT-----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAI--HVSGTNGTKR 78 (1273)
1136 Q Consensus 9 plvssqcvnlttrtqlp---payt-----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhai--hvsgtngtkr 78 (1273)
1137 ++....|...-...-++ |.++ -+-.+|+||||..++|+..+-.|+||.+.-++.+-+-.- |... .--.
1138 T Consensus 22 ~i~~~~C~~~~~~~~~~~~~~~~s~~~idvs~~~G~yYPd~rvysN~TlL~qGLFP~~gs~~~~Y~~sgt~~~s--~~~~ 99 (1275)
1139 T 6VSJ_C 22 YIGDFRCIQLVNSNGANVSAPSISTETVEVSQGLGTYYVLDRVYLNATLLLTGYYPVDGSKFRNLALRGTNSVS--LSWF 99 (1275)
1140 T ss_dssp CCSSBCCCCCSEECCCCCCCCCCCSCBCCCTTSTTCBCCTTCBCCSCCCEEEEEEECTTCBCCBCCCEESSEEC--GGGS
1141 T ss_pred cccCcceeEeecCCCCCCCCCCCcceeeeeecceeEEEeCCeEEeceeeeeccccCCCCCceeeEEeeccCCCC--cccc
1142 Confidence 34555677653333333 3444 345689999999999999999999999998887654222 2222 1346
1143
1144
1145 Q sp|P0DTC2|SPIK 79 FDNPVLPFNDGVYFASTEKSNI--------IRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNK 150 (1273)
1146 Q Consensus 79 fdnpvlpfndgvyfasteksni--------irgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyhknnk 150 (1273)
1147 +++++.||+||+++...+.+|- -..++||+|.+..+++++|+++-+...|.+|.|..|..|...+++.-+|.
1148 T Consensus 100 y~~~~~~F~dGIfVkV~~~kn~t~~~~~~~ypa~~fGSTF~Nts~tvVI~P~~~~r~itvCq~~vC~~p~~~~~p~~g~~ 179 (1275)
1149 T 6VSJ_C 100 QPPYLNQFNDGIFAKVQNLKTSTPSGATAYFPTIVIGSLFGYTSYTVVIEPYNGVIMASVCQYTICQLPYTDCKPNTNGN 179 (1275)
1150 T ss_dssp STTTSCCCSSCEEEEEECCGGGSCTTCCCSSCCEEEESSCSTTSCEEEECEETTEECCEEECCCBBSSCCEESSCCCSSC
1151 T ss_pred cCCcccccCCcEEEEeeeeccCCCCcchhccceeEEecccCCCceEEEEeCCCceeEeEEEEEEEcCCCeeEEccCCCCC
1152 Confidence 7788999999999998887765 35678999999999999999999999999999999999999888744332
1153
1154
1155 Q sp|P0DTC2|SPIK 151 SWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINL---VRDLPQGFSALEPLV 227 (1273)
1156 Q Consensus 151 swmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknidgyfkiyskhtpinl---vrdlpqgfsaleplv 227 (1273)
1157 +..+ ++. ....+|+|.|. +.|-+|... ..|- |.|+..||.|-+|..+...+. ..-+| |...+.+.
1158 T Consensus 180 ~~~~--~~~-~d~~nc~f~~~-~nfT~d~~~--~~~~----~~F~~~dG~fy~Yyad~~~~~~f~f~~~~-~~~~~~yy- 247 (1275)
1159 T 6VSJ_C 180 KLIG--FWH-TDVKPPICVLK-RNFTLNVNA--DAFY----FHFYQHGGTFYAYYADKPSATTFLFSVYI-GDILTQYY- 247 (1275)
1160 T ss_dssp TTCC--SSB-CCCSCCCEEEE-CCEECCTTC--SEEE----EEBCEETTEECCEECSSSSCBEECCCCCC-SSCCCEEE-
1161 T ss_pred ceee--ece-ecCCCCEEEEe-eeeccCccc--ceee----EEEEEcCCeEEEEEECCCcCcceeecccc-cceeceeE-
1162 Confidence 3322 233 67889999764 455444322 1221 999999999988876644332 11222 33333333
1163
1164
1165 Q sp|P0DTC2|SPIK 228 DLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFT 307 (1273)
1166 Q Consensus 228 dlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlksft 307 (1273)
1167 .+-|+..++ .+.+ ..++|||++|.+|+|||+|++||.||+||||+-|+++|-||..+||.
1168 T Consensus 248 ---------------v~~~~~~~~---~~~~--~~~~~~v~~L~~~~~ll~fd~~G~i~~avDC~~~~~~el~C~~~sf~ 307 (1275)
1169 T 6VSJ_C 248 ---------------VLPFICNPT---AGST--FAPRYWVTPLVKRQYLFNFNQKGVITSAVDCASSYTSEIKCKTQSML 307 (1275)
1170 T ss_dssp ---------------ECCEECCCS---SCSC--CCCEEEEEEEEEEEEECCBCSSSCBCCCBCTTSCHHHHHHHHHTSSS
1171 T ss_pred ---------------EeeeeecCC---CCCC--cccEEEEEeccceeEEEEecCCCeEeEEEecccCccceeeeEecccc
1172 Confidence 233444333 2223 67899999999999999999999999999999999999999999999
1173
1174
1175 Q sp|P0DTC2|SPIK 308 VEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKL 387 (1273)
1176 Q Consensus 308 vekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptkl 387 (1273)
1177 +++|+|++|+||+||....+|.++.+..|+|.++++|.++.++|.|.|+.++||..|+++|++..++++|+||||+|.||
1178 T Consensus 308 ~~~GVY~~s~y~a~p~~~v~~~~~~~~~C~~~~~~~~~~~P~p~~w~R~~~~nCnfn~s~Ll~~~~~~~f~C~~ispskl 387 (1275)
1179 T 6VSJ_C 308 PSTGVYELSGYTVQPVGVVYRRVANLPACNIEEWLTARSVPSPLNWERKTFQNCNFNLSSLLRYVQAESLFCNNIDASKV 387 (1275)
1180 T ss_dssp CCSSCEECCCCCCCCCCCCCCCCCCCCBCCTHHHHTCSEEECTTSCEEEEECSCBCCHHHHHHHSEEEECCBSSCCTTTS
1181 T ss_pred CCCceeecCCeEEEeeeEEEEecCCCCCCCHHHHHhcCCCCCchhcEEeEEecCCCCHHHHHhheeeccceecCCCHHHH
1182 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
1183
1184
1185 Q sp|P0DTC2|SPIK 388 NDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSK----VGGNYNYLYRLFRKSNLKP 463 (1273)
1186 Q Consensus 388 ndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldsk----vggnynylyrlfrksnlkp 463 (1273)
1187 .++||..|++|.|.|..+..++++||++|-|++||||+|+||+||+++|+-...+.. --++||+-|+.-++..++|
1188 T Consensus 388 ~~~CfssvtiD~F~ip~~~~~~l~~g~~g~i~~yNYkl~~~~~~C~l~~~~~~~~~~~t~~np~~~~~~~~~~~~~~f~~ 467 (1275)
1189 T 6VSJ_C 388 YGRCFGSISVDKFAVPRSRQVDLQLGNSGFLQTANYKIDTAATSCQLHYTLPKNNVTINNHNPSSWNRRYGFNDAGVFGK 467 (1275)
1190 T ss_dssp TTCCBSEEEEEEECCCSTTGGGGSTTCCSSHHHHTCCCCSSSCEEECEEEECTTTCEEECCCCCHHHHHHSCCTTTTTTT
1191 T ss_pred cccccCeeEEEEEeccchhceeecCCCCcHhHhccccCCCCCCceEEEEEcCcccccccCCCCccchhcccccccccccC
1192 Confidence 999999999999999999999999999999999999999999999999996543322 2357888888888899999
1193
1194
1195 Q sp|P0DTC2|SPIK 464 FERDISTEIY--QAGSTPCNG--V------------------EGFNCYF------------PLQSYGFQPTNGVGYQPY- 508 (1273)
1196 Q Consensus 464 ferdisteiy--qagstpcng--v------------------egfncyf------------plqsygfqptngvgyqpy- 508 (1273)
1197 +++|..-..+ ..+.+-|+. . .|..|+- |..+---+|+..+||+++
1198 T Consensus 468 ~~~dvvy~~~~~~~~~~~cpC~~~~~~~~ct~~~~~~~~~~~~~~~c~g~~vi~~~~g~~~~~~~c~c~~~af~gws~d~ 547 (1275)
1199 T 6VSJ_C 468 NQHDVVYAQQCFTVRSSFCPCAQPDIVSPCTTQTKPKSAFVNVGDHCEGLGVLEDNCGNADPHKGCICANNSFIGWSHDT 547 (1275)
1200 T ss_dssp CSSEEEEESCBBCCCSCCCSCC-----------CCCCBCCCCTTCCCCCBEECTTSEECCCSSSSCEECTTCEESEEEEE
1201 T ss_pred cccceeeccccccCCCCCCCCCCCCcCCCCCCCCCCccceeccccccceeEEeeccCCCCCCCCCccccCCcccccCccc
1202 Confidence 9999876533 233333330 0 1112211 001111256777888888
1203
1204
1205 Q sp|P0DTC2|SPIK 509 -----RVVVLSFELLHA--PATVCGP---KKSTNLVKNKCVNFNFNGLTGTGVLTESN-KKFLPFQQFGRDIADTTDAVR 577 (1273)
1206 Q Consensus 509 -----rvvvlsfellha--patvcgp---kkstnlvknkcvnfnfngltgtgvltesn-kkflpfqqfgrdiadttdavr 577 (1273)
1207 |++|+|++||++ ++|||+. +..++++.++||++|..|.||+||+++.+ ..+-.+|.+..+.+.-..++|
1208 T Consensus 548 c~~~~r~~i~~~~~ln~~~s~tvCp~~~~~~~t~I~ln~CVdYNIYGitGtGVItnvt~~~~~~~qgL~yS~sG~L~~FK 627 (1275)
1209 T 6VSJ_C 548 CLVNDRCQIFANILLNGINSGTTCSTDLQLPNTEVVTGICVKYDLYGITGQGVFKEVKADYYNSWQTLLYDVNGNLNGFR 627 (1275)
1210 T ss_dssp CEETTEEEEEEEEEEESTTCCSBBCSSSCCCCCCCCCSSCEEEEETTEEEEEEEECCCCCCCCSSCCCEECTTSCEEEEE
1211 T ss_pred cccCCceeeeeeeeccCCCCCCCCCCcCCCCCceEEeCeEEEEEeCCCeeEEEEEecCCcccccCccEEEeCCCCEEEEE
1212 Confidence 999999999998 8999998 34689999999999999999999999944 444466778888889999999
1213
1214
1215 Q sp|P0DTC2|SPIK 578 DPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVN 657 (1273)
1216 Q Consensus 578 dpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvn 657 (1273)
1217 ++.++++..|+||..+.++++..|. +...|+++..++|+++....+....+| .+.|+|-.||+++++|.+
1218 T Consensus 628 n~ttg~~YsV~PC~~v~qQvVV~~~--sivgalls~n~~cs~~~~n~~~~~~~~--------~~~~~t~~gCv~~a~~~t 697 (1275)
1219 T 6VSJ_C 628 DLTTNKTYTIRSCYSGRVSAAFHKD--APEPALLYRNINCSYVFSNNISREENP--------LNYFDSYLGCVVNADNRT 697 (1275)
1220 T ss_dssp CTTTCCEEEEECCCCCEEECCCCTT--CSSCCEEETTCCHHHHHHTTCCSSCCC--------SCCEECSSSEECSCSEEE
1221 T ss_pred cCCCCCEEEEEeCceeceeEEEeCC--CceeEEEEeccceeceeeccceeeeCC--------CcceeccccceeccccCC
1222 Confidence 9999999999999999999999876 567789999999999886444333333 344999999999999887
1223
1224
1225 Q sp|P0DTC2|SPIK 658 N--SYECDIPIGAGICASYQTQTNSPRRARSVASQ-SIIA---YT-MSLGAENSVAYSNNSIAIPTNFTISVTTEILPVS 730 (1273)
1226 Q Consensus 658 n--syecdipigagicasyqtqtnsprrarsvasq-siia---yt-mslgaensvaysnnsiaiptnftisvtteilpvs 730 (1273)
1227 + ..+|++|.|.|||+.+..-.-.+ |++..+ .+.. +. +..........+...|.||+||||+|++|-++++
1228 T Consensus 698 ~~~~~~c~~~~g~giC~dg~~~~~~~---~~~~~~~~~~~~~~~~~~~~~~s~~~~~~~~~i~IP~nFtlsv~~EyiQt~ 774 (1275)
1229 T 6VSJ_C 698 DEALPNCDLRMGAGLCVDYSKSRRAH---RSVSTGYRLTTFEPYTPMLVNDSVQSVDGLYEMQIPTNFTIGHHEEFIQTR 774 (1275)
1230 T ss_dssp EEEESSCSEEETTTEEEEECTTTCSS---SSSTTSEEEEEECSCCCCBCCCSCSSSCCBCSCCBCCCCEEECCEEECCCC
1231 T ss_pred CCcCCCCCCccceEEccCcccceecc---cccCCCceeecccCCcccccCCCCCccCcceEEEccCceEEEEEEEEeecC
1232 Confidence 5 68999999999999998833222 221111 1111 11 1111125566777899999999999999999999
1233
1234
1235 Q sp|P0DTC2|SPIK 731 MTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTP-P----I-KDFGGFNFSQ 804 (1273)
1236 Q Consensus 731 mtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktp-p----i-kdfggfnfsq 804 (1273)
1237 |.|.+|||.+|+||++.+|.+||.|||+||..+|+||.|.+..+|....++++.+++.++.+ + | ...|+|||+.
1238 T Consensus 775 ~~kVsIDCa~YVC~g~~rC~~LL~QYgsfC~~I~~aL~~~~~~~d~~~~~~~~~~~~~~~~s~~~~~~~~~~~~~fN~s~ 854 (1275)
1239 T 6VSJ_C 775 SPKVTIDCAAFVCGDNTACRQQLVEYGSFCVNVNAILNEVNNLLDNMQLQVASALMQGVTISSRLPDGISGPIDDINFSP 854 (1275)
1240 T ss_dssp CCEEECCHHHHHSCSSHHHHHHHGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCCCCBCC----------------
1241 T ss_pred CCCeEEEhhheecCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhccccccccCCCCCCCCCCCccchh
1242 Confidence 99999999999999999999999999999999999999999999999999999999998875 2 2 4456799999
1243
1244
1245 Q sp|P0DTC2|SPIK 805 ILPD-----------PSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQY 873 (1273)
1246 Q Consensus 805 ilpd-----------pskpskrsfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdemiaqy 873 (1273)
1247 +||. |+++++||+|||||||||+.+|.|+.+.|.+|.+...+|||+|||.|||+.||||++++||+|.|
1248 T Consensus 855 ll~~~~~~~~~~~~~~~~~~~RSaIEDLLF~KV~t~glG~~~~Yk~Ct~g~~i~DL~CAQyyNGImVLPpvvd~~~~amY 934 (1275)
1249 T 6VSJ_C 855 LLGCIGSTCAEDGNGPSAIRGRSAIEDLLFDKVKLSDVGFVEAYNNCTGGQEVRDLLCVQSFNGIKVLPPVLSESQISGY 934 (1275)
1250 T ss_dssp ------CCSSCCSSSTTTTTTTTHHHHHHHHHCSSCTTHHHHHHHHHHTTSSTTSSHHHHHHTTCEEECCSSCHHHHHHH
1251 T ss_pred hcccccCCcccCCCCCCccCcccHHHHHHcceeeecCCchHHHHHhccCCcchHHhhcccccCcEEEeCCCCCHHHHHHH
1252 Confidence 9986 56668999999999999999999999999999999999999999999999999999999999999
1253
1254
1255 Q sp|P0DTC2|SPIK 874 TSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVN 953 (1273)
1256 Q Consensus 874 tsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvn 953 (1273)
1257 |++|++|....|||+ |..||||+||.||+||+|+||+||.||||+|||.||.||+.||+.++++++||.|+|||||
1258 T Consensus 935 TasL~g~m~~gg~Ta----aaaIPFa~~vq~RlN~v~lt~~VL~~NQk~iA~sFN~A~~~iq~~f~~~~~Al~kiQ~VVN 1010 (1275)
1259 T 6VSJ_C 935 TTGATAAAMFPPWSA----AAGVPFSLSVQYRINGLGVTMNVLSENQKMIASAFNNALGAIQDGFDATNSALGKIQSVVN 1010 (1275)
1260 T ss_dssp HHHHHHTTSCSSSCS----STTCCHHHHHHHHGGGTSCHHHHTTHHHHHHHHHHHHHHHHHHHHHSSCCHHHHHHHHHHH
1261 T ss_pred HHHHHHHhhcccchh----cccCchHHHHHHHhcccccchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
1262 Confidence 999999999999997 5568999999999999999999999999999999999999999999999999999999999
1263
1264
1265 Q sp|P0DTC2|SPIK 954 QNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECV 1033 (1273)
1266 Q Consensus 954 qnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecv 1033 (1273)
1267 ++++||++|++||+.|||||||.++||++|||++||++||||||+|||.+|++||+|||+|++|+|||+.||..||.|||
1268 T Consensus 1011 ~q~~aL~~L~~qL~~nFgAISssI~dIy~RLD~leAdaQVDRLItGRL~aLnafVtQ~L~~~~evr~sr~LA~qKINECV 1090 (1275)
1269 T 6VSJ_C 1011 ANAEALNNLLNQLSNRFGAISASLQEILTRLEAVEAKAQIDRLINGRLTALNAYISKQLSDSTLIKVSAAQAIEKVNECV 1090 (1275)
1270 T ss_dssp HHHHHHHHHHHGGGSCCSSSCSCHHHHHHHSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
1271 T ss_pred HHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
1272 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
1273
1274
1275 Q sp|P0DTC2|SPIK 1034 LGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVSNGTHWFVTQRNFYEP 1112 (1273)
1276 Q Consensus 1034 lgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregvfvsngthwfvtqrnfyep 1112 (1273)
1277 ..||+|.+|||.|.|++|+||.||+|++|+|++|+|.+.++.+++|.+|+++ ++..|+.|+|+.+...|++|.|++|||
1278 T Consensus 1091 KSQS~R~gFCGnGtHi~Si~q~APnGi~FlH~~y~Pt~~~~V~a~~GlC~~~~~~~~p~~g~fv~~n~~~~iT~r~~Y~P 1170 (1275)
1279 T 6VSJ_C 1091 KSQTTRINFCGNGNHILSLVQNAPYGLYFIHFSYVPISFTTANVSPGLCISGDRGLAPKAGYFVQDDGEWKFTGSSYYYP 1170 (1275)
1280 T ss_dssp CSCCSSSSCSSSSCCCCCCEECCTTSCEEECCEEECCSCCCCBCCTTCCSCCCSSSCCCCSCCCBCSSSSBCCCSSBCCC
1281 T ss_pred hcCCCcccccCCCeEEEEeeeccCCeEEEEEEEecccceEEEEEEeeeEecCCceEEecCeEEEecCCEEEEeccCcccC
1282 Confidence 9999999999999999999999999999999999999999999999999994 899999999999988999999999999
1283
1284
1285 Q sp|P0DTC2|SPIK 1113 QIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLG-DISGINASVVN----IQKEIDRLN 1187 (1273)
1286 Q Consensus 1113 qiittdntfvsgncdvvigivnntvydplqpeldsfkeeldkyfknhtspdvdlg-disginasvvn----iqkeidrln 1187 (1273)
1287 ..||.+|...-..|||...-+|+++..|..|++..|+|||+|+|||+++...|++ |++.+|+++++ ++.++++|+
1288 T Consensus 1171 r~it~~d~v~~~sC~v~y~n~~~~~l~~~~p~~~df~~el~~~~~n~~~~~p~~~~~~~~~N~t~L~Ei~~l~~~~~~l~ 1250 (1275)
1289 T 6VSJ_C 1171 EPITDKNSVIMSSCAVNYTKAPEVFLNTSIPNPPDFKEELDKWFKNQTSIAPDLSLDFEKLNVTLIKRMKQIEDKIEEIE 1250 (1275)
1290 T ss_dssp CSSCCC--------------------------------------------------------------------------
1291 T ss_pred CCCCccceEEeeccccEEEEcccccCCCCCCCCCChHHHHHHHHhcCCCCCCCcCCCHHHccHHHHHHHHHHHHHHHHHH
1292 Confidence 9999999999999999999999999999999999999999999999999666664 38899999986 666666666
1293
1294
1295 Q sp|P0DTC2|SPIK 1188 EVAKNLNESLIDLQELG 1204 (1273)
1296 Q Consensus 1188 evaknlneslidlqelg 1204 (1273)
1297 ++.++||.++.++..+.
1298 T Consensus 1251 ~~i~~in~~~~~~~~~~ 1267 (1275)
1299 T 6VSJ_C 1251 SKQKKIENEIARIKKIK 1267 (1275)
1300 T ss_dssp -----------------
1301 T ss_pred HHHHHHHHHHHHHHHhc
1302 Confidence 66777777766665543
1303
1304
1305 No 8
1306 >6OHW_A Spike surface glycoprotein; Coronavirus spike glycoprotein, sialic acid; HET: MAN, NAG, BMA; 2.9A {Human coronavirus OC43}
1307 Probab=100.00 E-value=7.3e-190 Score=1602.12 Aligned_cols=1144 Identities=29% Similarity=0.505 Sum_probs=895.1 Template_Neff=3.700
1308
1309 Q sp|P0DTC2|SPIK 2 FVFLVLLP-----LVSSQCVNLTTRTQLP---PAYT-----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAI 68 (1273)
1310 Q Consensus 2 fvflvllp-----lvssqcvnlttrtqlp---payt-----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhai 68 (1273)
1311 |+|+.|+| +....|.. ....-+. |.++ -+-.+|+||||..++++..+-.|++|.+.-++.+-.-
1312 T Consensus 13 ~~~~~~~~~~~~~i~~~~C~~-~~~~~~~~~~~~~~~~~id~s~~~G~yYp~~rvysN~tll~~glfp~~gs~~~~y~-- 89 (1322)
1313 T 6OHW_A 13 YLLGMLVASVLAVIGDLKCTS-DNINDKDTGPPPISTDTVDVTNGLGTYYVLDRVYLNTTLFLNGYYPTSGSTYRNMA-- 89 (1322)
1314 T ss_dssp ------------CCSSBCCCC-TTEECCCCCSCCEEEEECCCTTSTTCBCCTEEECCSEEEEEEEEEECTTCEEEECC--
1315 T ss_pred HHHHHHHHHHHHHhcCccccc-cCCCCCCCCCCCCCcceeecccCceeEEecCeEEeeeeeEecceecCCCCceEEee--
1316 Confidence 56666655 33445765 2222222 3333 3456899999999999999999999999877665321
1317
1318
1319 Q sp|P0DTC2|SPIK 69 HVSGTNG---TKRFDNPVLPFNDGVYFASTEKSNIIRGW---------IFGTTLDSKTQSLLIVNNATN----------- 125 (1273)
1320 Q Consensus 69 hvsgtng---tkrfdnpvlpfndgvyfasteksniirgw---------ifgttldsktqsllivnnatn----------- 125 (1273)
1321 .+|++- --.++++..||+||++....+..|. +|| +||+|.+...++++|.++-.+
1322 T Consensus 90 -~~~t~~~s~~~~y~~~~~~F~dGifvkv~~~~~~-t~~~~~~~yp~~~fGstf~N~s~tvVI~P~~~~~~~~~~~~~~~ 167 (1322)
1323 T 6OHW_A 90 -LKGSVLLSRLWFKPPFLSDFINGIFAKVKNTKVI-KDRVMYSEFPAITIGSTFVNTSYSVVVQPRTINSTQDGDNKLQG 167 (1322)
1324 T ss_dssp -CEESSCEEGGGGSTTTEEECSSEEEEEEECEEEE-ETTEEEEECCCEEEESSCSTTSCEEEEEEEEEC-------CCEE
1325 T ss_pred -eecccccccccccCCccccccCcEEEEEEeeccc-CCCceeeccCceEEeccccCCeeEEEEccCCCCcCccccccccc
1326 Confidence 223322 2456777889999997766655544 444 699999999999999987664
1327
1328
1329 Q sp|P0DTC2|SPIK 126 -VVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIY 204 (1273)
1330 Q Consensus 126 -vvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknidgyfkiy 204 (1273)
1331 ..|.+|.|..|..|...+++.-+| +. -+++. ....+|+|.|. +.|-.|... ..|- |.|++.||.|-+|
1332 T Consensus 168 ~~~it~C~~~vC~~p~~~~~~~~gn-~~--~~~~~-~d~~~~~~~~~-~nfT~d~~~--~~~~----f~F~q~~G~fy~Y 236 (1322)
1333 T 6OHW_A 168 LLEVSVCQYNMCEYPQTICHPNLGN-HR--KELWH-LDTGVVSCLYK-RNFTYDVNA--DYLY----FHFYQEGGTFYAY 236 (1322)
1334 T ss_dssp EEEEEEECCCEEEEEEEECCTTTCC-SS--CCEEE-CCSSCCCEEEE-EEEEECTTC--SEEE----EEEEEETTEEEEE
1335 T ss_pred ceEEeeeeeEecCCCeeEEecCCCC-Cc--eeeeE-eecCCceEEEe-eeecccccc--ceee----EEEEEeCCeEEEE
1336 Confidence 347899999999999988875444 22 23444 66788998765 455444322 1111 9999999999887
1337
1338
1339 Q sp|P0DTC2|SPIK 205 SKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGT 284 (1273)
1340 Q Consensus 205 skhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengt 284 (1273)
1341 ..+...+. .| +...+.|...+++- .+-|+..++ ..++|||++|.+|+|||+|++||.
1342 T Consensus 237 y~d~~~~~------~f-----~f~~~~~~~~~~yy---v~p~~~~~~---------~~~~~~v~~L~~~~~Ll~fd~~G~ 293 (1322)
1343 T 6OHW_A 237 FTDTGVVT------KF-----LFNVYLGMALSHYY---VMPLTCNSK---------LTLEYWVTPLTSRQYLLAFNQDGI 293 (1322)
1344 T ss_dssp EESSSSSB------EE-----EEEEECSSCCCEEE---ECCEECSSC---------CCCCEEEEEEEEEEEEEEECTTSC
1345 T ss_pred EecCCCCc------ce-----eccccceeccceeE---eceeecCCc---------cceeEEEEeceeeeEEEEecCCCe
1346 Confidence 44432221 00 01111122222222 222333332 668999999999999999999999
1347
1348
1349 Q sp|P0DTC2|SPIK 285 ITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVAD 364 (1273)
1350 Q Consensus 285 itdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvad 364 (1273)
1351 ||+||||+-|+++|-||..+||.+++|+|++|+||+||...++|.+.....|+|.++++|.++.++|.|.|+.++||..|
1352 T Consensus 294 It~AvDC~~~~~sEl~C~t~sf~~~tGVY~lS~y~aqp~~~V~~~~~~~~~C~~~~~~~~~~~P~p~~w~R~~f~nCnfn 373 (1322)
1353 T 6OHW_A 294 IFNAVDCMSDFMSEIKCKTQSIAPPTGVYELNGYTVQPIADVYRRKPNLPNCNIEAWLNDKSVPSPLNWERKTFSNCNFN 373 (1322)
1354 T ss_dssp EEEEEETTSSHHHHHHHHTTCSSCCSEEEEEEEEECCCSEEEEECCSSCCBCCHHHHHTCSEEECSTTCEEEEEESCBBC
1355 T ss_pred EeEEEecccCcchhheeeecccCCCCceeecCCeEEEeeeEEEEeCCCCCCCCHHHHhcCCCCCCccceEEeEEecCCCC
1356 Confidence 99999999999999999999999999999999999999999999999988999999999999999999999999999999
1357
1358
1359 Q sp|P0DTC2|SPIK 365 YSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSK 444 (1273)
1360 Q Consensus 365 ysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldsk 444 (1273)
1361 +++|++...+++|+||||+|.||.+.||..|++|.|.|..+..++++||.+|.|++||||+|++|+||+++|+-.+.+..
1362 T Consensus 374 ~s~ll~~~~~~~f~C~~ispskl~~~C~ssvtiD~F~ip~~~~~~l~~g~~g~~~~~NYkl~~~~~~C~l~y~~~~~nvn 453 (1322)
1363 T 6OHW_A 374 MSSLMSFIQADSFTCNNIDAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATSCQLYYNLPAANVS 453 (1322)
1364 T ss_dssp HHHHHHHCEEEEEEEESSCGGGGGGCEEEEEEEEEEECCTTCGGGGSTTCCCHCCCCCCCCCSSSCEEEEEEEEEGGGCE
1365 T ss_pred HHHHhhhceeceeeecCCCHHHHcccccceeEEEEEeccCCcceeecCCCCcHHHhcCccCCCCCCceEEEEEccccccc
1366 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999995554333
1367
1368
1369 Q sp|P0DTC2|SPIK 445 V----GGNYNYLYRLFRKSNLKPFERDI---STEIYQ-----AGSTPCN----------G-------------------- 482 (1273)
1370 Q Consensus 445 v----ggnynylyrlfrksnlkpferdi---steiyq-----agstpcn----------g-------------------- 482 (1273)
1371 + -++||.-|+.-..+.++|.++.. ...+|. .+.+-|+ +
1372 T Consensus 454 ~t~~Nps~wn~ry~f~~~~~~~~~~~~~~~~hdvvYs~~cf~~~~~yCPC~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~ 533 (1322)
1373 T 6OHW_A 454 VSRFNPSTWNKRFGFIEDSVFKPRPAGVLTNHDVVYAQHCFKAPKNFCPCKLNGSCVGSGPGKNNGIGTCPAGTNYLTCD 533 (1322)
1374 T ss_dssp EECCCCCHHHHHTTCCHHHHSCBTTTSSBCTTEEEEESCCEECCTTCCCCBCC-----------CCBBCCCTTCCCBCC-
1375 T ss_pred cccCCccchhhccCcccccccCCCCCCcCCCcceeeeeeeecCCCCcCCCcCCCcccCCCCCCCCCCCcCCCCccccccc
1376 Confidence 2 34677777766667777765411 112222 2222121 0
1377
1378
1379 Q sp|P0DTC2|SPIK 483 ----VEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFEL-----------------------------------LHAPAT 523 (1273)
1380 Q Consensus 483 ----vegfncyfplqsygfqptngvgyqpyrvvvlsfel-----------------------------------lhapat 523 (1273)
1381 ..+..|.-+...+--....|+|+++++++|++++. ...+.|
1382 T Consensus 534 ~~~~~~~~~~~~~~~~~q~~~~~gvg~~c~gl~Vi~~k~g~~~C~C~~~af~g~~~~~~~~~~~~~i~~~~~~~~~~s~t 613 (1322)
1383 T 6OHW_A 534 NLCTPDPITFTGTYKCPQTKSLVGIGEHCSGLAVKSDYCGGNSCTCRPQAFLGWSADSCLQGDKCNIFANFILHDVNSGL 613 (1322)
1384 T ss_dssp ---TTCSSSCCCSSCCSSEECCCCTTCCCCCCEECGGGEEBTTTEECGGGEESEEEEECEETTEEEEEEEEEEEEETSSS
1385 T ss_pred cCCCCCCCccccccCCCCceeeeecccccceEEEEecccCCCCccCCCccccCCCcccccCCCccccccceeecCCCCCC
1386 Confidence 01122211111111123569999999999999988 667889
1387
1388
1389 Q sp|P0DTC2|SPIK 524 VCGP---KKSTNLVKNKCVNFNFNGLTGTGVLTESN-KKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVIT 599 (1273)
1390 Q Consensus 524 vcgp---kkstnlvknkcvnfnfngltgtgvltesn-kkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvit 599 (1273)
1391 ||++ +.+++++.++||++|..|.||+||+++++ ..++.++.+..|-+.-..+++++.++++..|+||..|.++++.
1392 T Consensus 614 vC~~d~~~~~snI~Ln~CVdYNIYGitGqGVItn~n~~~~~~~~GL~ydssgdL~gfKn~ttg~~YsV~PC~~g~VVGi~ 693 (1322)
1393 T 6OHW_A 614 TCSTDLQKANTDIILGVCVNYDLYGILGQGIFVEVNATYYNSWQNLLYDSNGNLYGFRDYITNRTFMIRSCYSGRVSAAF 693 (1322)
1394 T ss_dssp EEBCSSCCCCCCCCBSSEEEEEETTEEEEEEEEEECCCCCCTTEEEEECTTSCEEEEECTTTCCEEEEECCCEEEEEEEE
1395 T ss_pred cCCCcccccCceEEeCeeeeEEeCCccceEEEEecCCCceeccCcEEEcCCCCEEEEEcCCCCcEEEEEeCccCcEEEEE
1396 Confidence 9998 56799999999999999999999999964 5566778888888888889999999999999999999999998
1397
1398
1399 Q sp|P0DTC2|SPIK 600 PGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVN--NSYECDIPIGAGICASYQTQ 677 (1273)
1400 Q Consensus 600 pgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvn--nsyecdipigagicasyqtq 677 (1273)
1401 ... ++..+.+|.++.|.+|....|..+++| .+-|+|-.||++++.+.. ...+|++|.|.|+|+.|.+
1402 T Consensus 694 tS~--n~t~a~lF~n~~C~~v~~~~~~~~~~~--------~~~f~t~~Gcv~~a~~~t~~~v~~c~~~~g~~~C~~~~~- 762 (1322)
1403 T 6OHW_A 694 HAN--SSEPALLFRNIKCNYVFNNSLTRQLQP--------INYFDSYLGCVVNAYNSTAISVQTCDLTVGSGYCVDYSK- 762 (1322)
1404 T ss_dssp CTT--CSSCEEEEETCCHHHHHHTTTTTTCCC--------SCEEECSSEEEESSEEEEEEEESCCSEEEETTEEEEEC--
1405 T ss_pred eCC--CCCccceeccceeceeeecccceeecc--------ccceeccccceecceecCCceeccccccccCceeeecCC-
1406 Confidence 765 445789999999999998766655555 233999999999999986 4889999999999999988
1407
1408
1409 Q sp|P0DTC2|SPIK 678 TNSPRRARSVAS--QSIIAYTMSL-----GAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECS 750 (1273)
1410 Q Consensus 678 tnsprrarsvas--qsiiaytmsl-----gaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecs 750 (1273)
1411 |+++++... ..+..| +.+ ........+...|.||+||||+|++|-++++|.|.+|||.+|+||++.+|.
1412 T Consensus 763 ---~~gs~~~~~~~~~l~~~-~p~~~~~v~~~~~~~~~~~~IsIP~NFTlsvt~EyIQt~~~kVsIDCa~YVC~~~~~C~ 838 (1322)
1413 T 6OHW_A 763 ---NGGSGGAITTGYRFTNF-EPFTVNSVNDSLEPVGGLYEIQIPSEFTIGNMVEFIQTSSPKVTIDCAAFVCGDYAACK 838 (1322)
1414 T ss_dssp -----------CCSEEEEEE-CCCCCEEECCCSSCBTTBEEEEEEEEEEEEEEEEEEECCCCEEEECHHHHHSCSCHHHH
1415 T ss_pred ---CCCCCceeccCceeeec-cceeecccccCCCCCcceEEEEecCceeeEEEEEEeeecCCCeEEehhheecCCCHHHH
1416 Confidence 444433222 222233 222 111223455568999999999999999999999999999999999999999
1417
1418
1419 Q sp|P0DTC2|SPIK 751 NLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKT----PPIKDF--GGFNFSQILPDPS----KPSKRSFIED 820 (1273)
1420 Q Consensus 751 nlllqygsfctqlnraltgiaveqdkntqevfaqvkqiykt----ppikdf--ggfnfsqilpdps----kpskrsfied 820 (1273)
1421 +||.|||+||..+|+||.+++..+|....+++..+++-++. +.+..| |+||||.+||.+. .+++||+|||
1422 T Consensus 839 ~LL~QYgs~C~~I~~aL~~v~~~~d~~~~~~~~~~~~~~~~s~~l~~~~~~~~g~fN~s~ll~~~~s~~~~~~~RSaIED 918 (1322)
1423 T 6OHW_A 839 SQLVEYGSFCDNINAILTEVNELLDTTQLQVANSLMNGVTLSTKLKDGVNFNVDDINFSPVLGCLGSECSKASSRSAIED 918 (1322)
1424 T ss_dssp HHGGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTCEEEGGGGTCCCCEETTEECTTTCCCCCC----CCSSCHHHH
1425 T ss_pred HHHHHHHHHHHHHHHHHHHHHHhccHHHHHHHHHHhcCccccccccccccCCCCCccccccccCCCCCCCcCccccHHHH
1426 Confidence 99999999999999999999999999999999999998876 444445 6899999999875 3578999999
1427
1428
1429 Q sp|P0DTC2|SPIK 821 LLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAM 900 (1273)
1430 Q Consensus 821 llfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfam 900 (1273)
1431 |||+||..+|.|+.+.|.+|.+...+|||+|||.|||+.||||++++||++.||++|++|....|||+ |..||||+
1432 T Consensus 919 LLFnKV~tsglG~~~~Yk~Ct~g~~i~DL~CAQyyNGImVLPpVvd~~~~amYTaSL~g~m~~gg~Ta----aaaIPFa~ 994 (1322)
1433 T 6OHW_A 919 LLFDKVKLSDVGFVEAYNNCTGGAEIRDLICVQSYKGIKVLPPLLSENQFSGYTLAATSASLFPPWTA----AAGVPFYL 994 (1322)
1434 T ss_dssp HHHHTCSCSHHHHHHHHTTTTTTSCTTCHHHHHHHTTEEEECCSSCHHHHHHHHHHHHHTTTSSSCGG----GTTCCHHH
1435 T ss_pred HHcceeeeCCcchHHHhHhccCCccHHHhhccceeCcEEEeCCCCCHHHHHHHHHHHHHHhhccCchh----cccCcchH
1436 Confidence 99999999999999999999999999999999999999999999999999999999999999999997 55689999
1437
1438
1439 Q sp|P0DTC2|SPIK 901 QMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDI 980 (1273)
1440 Q Consensus 901 qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndi 980 (1273)
1441 ||.||+||+|+||+||.||||+|||.||.||+.||+.++.|++||.|+|||||++++||++|++||+.|||||||.++||
1442 T Consensus 995 ~vq~RlN~v~lt~~VL~~NQk~iA~sFN~Ai~~iq~~f~tt~~AL~KiQ~VVN~q~~aL~~L~~qL~~nFgAISssI~DI 1074 (1322)
1443 T 6OHW_A 995 NVQYRINGLGVTMDVLSQNQKLIANAFNNALYAIQEGFDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISASLQEI 1074 (1322)
1444 T ss_dssp HHHHHHHTTTCCHHHHTTCHHHHHHHHHHHHHHHHHTTTSCCHHHHHHHHHHHHHHHHHHHHHGGGGCCTTSSCSCHHHH
1445 T ss_pred HHHHHhcccccchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHH
1446 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
1447
1448
1449 Q sp|P0DTC2|SPIK 981 LSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGV 1060 (1273)
1450 Q Consensus 981 lsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgv 1060 (1273)
1451 ++|||++||++||||||+|||.+|++||+|||+|++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+||.||+|+
1452 T Consensus 1075 y~RLD~LEAdaQVDRLItGRL~aLNafVtQ~L~~~~eVr~sr~LA~qKINECVKSQS~R~gFCGnG~Hi~Si~q~AP~Gi 1154 (1322)
1453 T 6OHW_A 1075 LSRLDALEAEAQIDRLINGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAPYGL 1154 (1322)
1454 T ss_dssp HHHSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCSCCCSCSSCSTTSSEEEEEEEEETTEE
1455 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcccccCCCCCCeeEEEeeeccCCeE
1456 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
1457
1458
1459 Q sp|P0DTC2|SPIK 1061 VFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYD 1139 (1273)
1460 Q Consensus 1061 vflhvtyvpaqeknfttapaichdg-kahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvyd 1139 (1273)
1461 +|+|.+|+|.+.++.+++|.+|++| ++..|++|+|+.+...|++|.|++|+|..||.+|...-..|||...-+|+++..
1462 T Consensus 1155 ~F~H~~~~Pt~~~~V~a~~GlC~~~~~~~~~~~g~f~~~n~~~~~T~r~~y~Pr~~t~~d~v~~~sC~v~y~n~~~~~l~ 1234 (1322)
1463 T 6OHW_A 1155 YFIHFSYVPTKYVTARVSPGLCIAGDRGIAPKSGYFVNVNNTWMYTGSGYYYPEPITENNVVVMSTCAVNYTKAPYVMLN 1234 (1322)
1464 T ss_dssp EEEEEEEEEEEEEEEEEESCEECTTSCEEEESSEEEEEETTEEEEEETTEEEEEECCGGGEEEESSCCTTSEECTTCCCC
1465 T ss_pred EEEEeEecccceEEEEEeeeEEecCCeeEEecceEEEeeCCEEEEeccCcccCCCCCccceEEeccceeEEEEcCcccCC
1466 Confidence 9999999999999999999999995 899999999999988999999999999999999999999999999999999999
1467
1468
1469 Q sp|P0DTC2|SPIK 1140 PLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNI-QKEIDRLNEVAKNLNESLIDLQELG 1204 (1273)
1470 Q Consensus 1140 plqpeldsfkeeldkyfknhtspdvdlgdisginasvvni-qkeidrlnevaknlneslidlqelg 1204 (1273)
1471 |..|++..|+|||+|+|||+++...|+.. .-+|++++|+ ++||++|++++|+|+..-.+||.+-
1472 T Consensus 1235 ~~~p~~~df~~el~~~~~n~~~~~p~~~~-~~~N~t~Lnlt~~Ei~~L~~~~~~L~~~~~el~~~I 1299 (1322)
1473 T 6OHW_A 1235 TSIPNLPDFKEELDQWFKNQTSVAPDLSL-DYINVTFLDLLIKRMKQIEDKIEEIESKQKKIENEI 1299 (1322)
1474 T ss_dssp ------------------------------------------------------------------
1475 T ss_pred CCCCCCCChHHHHHHHHhcCCCCCCCCCc-cccccceecccHHHHHHHHHHHHHHHHHHHHHHHHH
1476 Confidence 99999999999999999999985555543 2299999999 6999999999999999888887654
1477
1478
1479 No 9
1480 >6NZK_A Spike surface glycoprotein; Coronavirus spike glycoprotein, sialic acid; HET: MJJ, MAN, NAG, BMA; 2.8A {Human coronavirus OC43}
1481 Probab=100.00 E-value=7.3e-190 Score=1602.12 Aligned_cols=1144 Identities=29% Similarity=0.505 Sum_probs=895.1 Template_Neff=3.700
1482
1483 Q sp|P0DTC2|SPIK 2 FVFLVLLP-----LVSSQCVNLTTRTQLP---PAYT-----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAI 68 (1273)
1484 Q Consensus 2 fvflvllp-----lvssqcvnlttrtqlp---payt-----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhai 68 (1273)
1485 |+|+.|+| +....|.. ....-+. |.++ -+-.+|+||||..++++..+-.|++|.+.-++.+-.-
1486 T Consensus 13 ~~~~~~~~~~~~~i~~~~C~~-~~~~~~~~~~~~~~~~~id~s~~~G~yYp~~rvysN~tll~~glfp~~gs~~~~y~-- 89 (1322)
1487 T 6NZK_A 13 YLLGMLVASVLAVIGDLKCTS-DNINDKDTGPPPISTDTVDVTNGLGTYYVLDRVYLNTTLFLNGYYPTSGSTYRNMA-- 89 (1322)
1488 T ss_dssp ------------CCSSBCCCC-TTEECCCCCSCCBCSSCCCCTTSTTCBCCTEEECCSEEEEEEEEECCTTCCCEECC--
1489 T ss_pred HHHHHHHHHHHHHhcCccccc-cCCCCCCCCCCCCCcceeecccCceeEEecCeEEeeeeeEecceecCCCCceEEee--
1490 Confidence 56666655 33445765 2222222 3333 3456899999999999999999999999877665321
1491
1492
1493 Q sp|P0DTC2|SPIK 69 HVSGTNG---TKRFDNPVLPFNDGVYFASTEKSNIIRGW---------IFGTTLDSKTQSLLIVNNATN----------- 125 (1273)
1494 Q Consensus 69 hvsgtng---tkrfdnpvlpfndgvyfasteksniirgw---------ifgttldsktqsllivnnatn----------- 125 (1273)
1495 .+|++- --.++++..||+||++....+..|. +|| +||+|.+...++++|.++-.+
1496 T Consensus 90 -~~~t~~~s~~~~y~~~~~~F~dGifvkv~~~~~~-t~~~~~~~yp~~~fGstf~N~s~tvVI~P~~~~~~~~~~~~~~~ 167 (1322)
1497 T 6NZK_A 90 -LKGSVLLSRLWFKPPFLSDFINGIFAKVKNTKVI-KDRVMYSEFPAITIGSTFVNTSYSVVVQPRTINSTQDGDNKLQG 167 (1322)
1498 T ss_dssp -CEESSCEEGGGGSTTTEEECSSEEEEEEECEEEE-ETTEEEEECCCEEEESSCSTTSCEEEEEEEEEC-------CCEE
1499 T ss_pred -eecccccccccccCCccccccCcEEEEEEeeccc-CCCceeeccCceEEeccccCCeeEEEEccCCCCcCccccccccc
1500 Confidence 223322 2456777889999997766655544 444 699999999999999987664
1501
1502
1503 Q sp|P0DTC2|SPIK 126 -VVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIY 204 (1273)
1504 Q Consensus 126 -vvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknidgyfkiy 204 (1273)
1505 ..|.+|.|..|..|...+++.-+| +. -+++. ....+|+|.|. +.|-.|... ..|- |.|++.||.|-+|
1506 T Consensus 168 ~~~it~C~~~vC~~p~~~~~~~~gn-~~--~~~~~-~d~~~~~~~~~-~nfT~d~~~--~~~~----f~F~q~~G~fy~Y 236 (1322)
1507 T 6NZK_A 168 LLEVSVCQYNMCEYPQTICHPNLGN-HR--KELWH-LDTGVVSCLYK-RNFTYDVNA--DYLY----FHFYQEGGTFYAY 236 (1322)
1508 T ss_dssp EEEEEEECCCEEEEEEEECCTTTCC-SS--CCEEE-CCSSCCCEEEE-EEEEECTTC--SEEE----EEEEEETTEEEEE
1509 T ss_pred ceEEeeeeeEecCCCeeEEecCCCC-Cc--eeeeE-eecCCceEEEe-eeecccccc--ceee----EEEEEeCCeEEEE
1510 Confidence 347899999999999988875444 22 23444 66788998765 455444322 1111 9999999999887
1511
1512
1513 Q sp|P0DTC2|SPIK 205 SKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGT 284 (1273)
1514 Q Consensus 205 skhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengt 284 (1273)
1515 ..+...+. .| +...+.|...+++- .+-|+..++ ..++|||++|.+|+|||+|++||.
1516 T Consensus 237 y~d~~~~~------~f-----~f~~~~~~~~~~yy---v~p~~~~~~---------~~~~~~v~~L~~~~~Ll~fd~~G~ 293 (1322)
1517 T 6NZK_A 237 FTDTGVVT------KF-----LFNVYLGMALSHYY---VMPLTCNSK---------LTLEYWVTPLTSRQYLLAFNQDGI 293 (1322)
1518 T ss_dssp EESSSSSB------EE-----EEEEECSSCCCEEE---ECCEECSSC---------CCCCEEEEECEEEEEEEEECTTSC
1519 T ss_pred EecCCCCc------ce-----eccccceeccceeE---eceeecCCc---------cceeEEEEeceeeeEEEEecCCCe
1520 Confidence 44432221 00 01111122222222 222333332 668999999999999999999999
1521
1522
1523 Q sp|P0DTC2|SPIK 285 ITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVAD 364 (1273)
1524 Q Consensus 285 itdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvad 364 (1273)
1525 ||+||||+-|+++|-||..+||.+++|+|++|+||+||...++|.+.....|+|.++++|.++.++|.|.|+.++||..|
1526 T Consensus 294 It~AvDC~~~~~sEl~C~t~sf~~~tGVY~lS~y~aqp~~~V~~~~~~~~~C~~~~~~~~~~~P~p~~w~R~~f~nCnfn 373 (1322)
1527 T 6NZK_A 294 IFNAVDCMSDFMSEIKCKTQSIAPPTGVYELNGYTVQPIADVYRRKPNLPNCNIEAWLNDKSVPSPLNWERKTFSNCNFN 373 (1322)
1528 T ss_dssp EEEEEETTSSHHHHHHHHTTCSSCCSEEEECCCEECCCSEEEEECCSSCCBCCHHHHHTCSEEECSTTCEEEEEESCEEC
1529 T ss_pred EeEEEecccCcchhheeeecccCCCCceeecCCeEEEeeeEEEEeCCCCCCCCHHHHhcCCCCCCccceEEeEEecCCCC
1530 Confidence 99999999999999999999999999999999999999999999999988999999999999999999999999999999
1531
1532
1533 Q sp|P0DTC2|SPIK 365 YSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSK 444 (1273)
1534 Q Consensus 365 ysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldsk 444 (1273)
1535 +++|++...+++|+||||+|.||.+.||..|++|.|.|..+..++++||.+|.|++||||+|++|+||+++|+-.+.+..
1536 T Consensus 374 ~s~ll~~~~~~~f~C~~ispskl~~~C~ssvtiD~F~ip~~~~~~l~~g~~g~~~~~NYkl~~~~~~C~l~y~~~~~nvn 453 (1322)
1537 T 6NZK_A 374 MSSLMSFIQADSFTCNNIDAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATSCQLYYNLPAANVS 453 (1322)
1538 T ss_dssp HHHHHHHCEEEEEEEESSCGGGGGGCEEEEEEEEEEECCTTCGGGGSTTCCCHCCCCCCCCCSSSCEEEEEEEEEGGGCE
1539 T ss_pred HHHHhhhceeceeeecCCCHHHHcccccceeEEEEEeccCCcceeecCCCCcHHHhcCccCCCCCCceEEEEEccccccc
1540 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999995554333
1541
1542
1543 Q sp|P0DTC2|SPIK 445 V----GGNYNYLYRLFRKSNLKPFERDI---STEIYQ-----AGSTPCN----------G-------------------- 482 (1273)
1544 Q Consensus 445 v----ggnynylyrlfrksnlkpferdi---steiyq-----agstpcn----------g-------------------- 482 (1273)
1545 + -++||.-|+.-..+.++|.++.. ...+|. .+.+-|+ +
1546 T Consensus 454 ~t~~Nps~wn~ry~f~~~~~~~~~~~~~~~~hdvvYs~~cf~~~~~yCPC~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~ 533 (1322)
1547 T 6NZK_A 454 VSRFNPSTWNKRFGFIEDSVFKPRPAGVLTNHDVVYAQHCFKAPKNFCPCKLNGSCVGSGPGKNNGIGTCPAGTNYLTCD 533 (1322)
1548 T ss_dssp EECCCCCHHHHHTTCCHHHHSCBTTTSSBCTTEEEEESSCEECCTTEEEEECC-----------CCBBCCCTTCEEECC-
1549 T ss_pred cccCCccchhhccCcccccccCCCCCCcCCCcceeeeeeeecCCCCcCCCcCCCcccCCCCCCCCCCCcCCCCccccccc
1550 Confidence 2 34677777766667777765411 112222 2222121 0
1551
1552
1553 Q sp|P0DTC2|SPIK 483 ----VEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFEL-----------------------------------LHAPAT 523 (1273)
1554 Q Consensus 483 ----vegfncyfplqsygfqptngvgyqpyrvvvlsfel-----------------------------------lhapat 523 (1273)
1555 ..+..|.-+...+--....|+|+++++++|++++. ...+.|
1556 T Consensus 534 ~~~~~~~~~~~~~~~~~q~~~~~gvg~~c~gl~Vi~~k~g~~~C~C~~~af~g~~~~~~~~~~~~~i~~~~~~~~~~s~t 613 (1322)
1557 T 6NZK_A 534 NLCTPDPITFTGTYKCPQTKSLVGIGEHCSGLAVKSDYCGGNSCTCRPQAFLGWSADSCLQGDKCNIFANFILHDVNSGL 613 (1322)
1558 T ss_dssp ---CSCSSSCCCSSCCSSEECCCCTTCCCCCCEECGGGEEBTTTEECGGGEESEEEEECEETTEEEEEEEEEEEEETSSS
1559 T ss_pred cCCCCCCCccccccCCCCceeeeecccccceEEEEecccCCCCccCCCccccCCCcccccCCCccccccceeecCCCCCC
1560 Confidence 01122211111111123569999999999999988 667889
1561
1562
1563 Q sp|P0DTC2|SPIK 524 VCGP---KKSTNLVKNKCVNFNFNGLTGTGVLTESN-KKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVIT 599 (1273)
1564 Q Consensus 524 vcgp---kkstnlvknkcvnfnfngltgtgvltesn-kkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvit 599 (1273)
1565 ||++ +.+++++.++||++|..|.||+||+++++ ..++.++.+..|-+.-..+++++.++++..|+||..|.++++.
1566 T Consensus 614 vC~~d~~~~~snI~Ln~CVdYNIYGitGqGVItn~n~~~~~~~~GL~ydssgdL~gfKn~ttg~~YsV~PC~~g~VVGi~ 693 (1322)
1567 T 6NZK_A 614 TCSTDLQKANTDIILGVCVNYDLYGILGQGIFVEVNATYYNSWQNLLYDSNGNLYGFRDYITNRTFMIRSCYSGRVSAAF 693 (1322)
1568 T ss_dssp EEECSSCCCCCCCCBSSEEEEEETTEEEEEEEEEECCCCCCTTEEEEECTTSCEEEEECTTTCCEEEEECCCEECCEEEE
1569 T ss_pred cCCCcccccCceEEeCeeeeEEeCCccceEEEEecCCCceeccCcEEEcCCCCEEEEEcCCCCcEEEEEeCccCcEEEEE
1570 Confidence 9998 56799999999999999999999999964 5566778888888888889999999999999999999999998
1571
1572
1573 Q sp|P0DTC2|SPIK 600 PGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVN--NSYECDIPIGAGICASYQTQ 677 (1273)
1574 Q Consensus 600 pgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvn--nsyecdipigagicasyqtq 677 (1273)
1575 ... ++..+.+|.++.|.+|....|..+++| .+-|+|-.||++++.+.. ...+|++|.|.|+|+.|.+
1576 T Consensus 694 tS~--n~t~a~lF~n~~C~~v~~~~~~~~~~~--------~~~f~t~~Gcv~~a~~~t~~~v~~c~~~~g~~~C~~~~~- 762 (1322)
1577 T 6NZK_A 694 HAN--SSEPALLFRNIKCNYVFNNSLTRQLQP--------INYFDSYLGCVVNAYNSTAISVQTCDLTVGSGYCVDYSK- 762 (1322)
1578 T ss_dssp CTT--CSSCEEEEETCCHHHHHHTTTTTTCCC--------SCEEEETTEEEESSEEEEEEEESCCSEEEETTEEEEEC--
1579 T ss_pred eCC--CCCccceeccceeceeeecccceeecc--------ccceeccccceecceecCCceeccccccccCceeeecCC-
1580 Confidence 765 445789999999999998766655555 233999999999999986 4889999999999999988
1581
1582
1583 Q sp|P0DTC2|SPIK 678 TNSPRRARSVAS--QSIIAYTMSL-----GAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECS 750 (1273)
1584 Q Consensus 678 tnsprrarsvas--qsiiaytmsl-----gaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecs 750 (1273)
1585 |+++++... ..+..| +.+ ........+...|.||+||||+|++|-++++|.|.+|||.+|+||++.+|.
1586 T Consensus 763 ---~~gs~~~~~~~~~l~~~-~p~~~~~v~~~~~~~~~~~~IsIP~NFTlsvt~EyIQt~~~kVsIDCa~YVC~~~~~C~ 838 (1322)
1587 T 6NZK_A 763 ---NGGSGGAITTGYRFTNF-EPFTVNSVNDSLEPVGGLYEIQIPSEFTIGNMVEFIQTSSPKVTIDCAAFVCGDYAACK 838 (1322)
1588 T ss_dssp -----------CCSEEEEEE-CCCCCEEECCCSSCBTTBEEEEEEEEEEEEEEEEEEECCCCEEEECHHHHHSCSCHHHH
1589 T ss_pred ---CCCCCceeccCceeeec-cceeecccccCCCCCcceEEEEecCceeeEEEEEEeeecCCCeEEehhheecCCCHHHH
1590 Confidence 444433222 222233 222 111223455568999999999999999999999999999999999999999
1591
1592
1593 Q sp|P0DTC2|SPIK 751 NLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKT----PPIKDF--GGFNFSQILPDPS----KPSKRSFIED 820 (1273)
1594 Q Consensus 751 nlllqygsfctqlnraltgiaveqdkntqevfaqvkqiykt----ppikdf--ggfnfsqilpdps----kpskrsfied 820 (1273)
1595 +||.|||+||..+|+||.+++..+|....+++..+++-++. +.+..| |+||||.+||.+. .+++||+|||
1596 T Consensus 839 ~LL~QYgs~C~~I~~aL~~v~~~~d~~~~~~~~~~~~~~~~s~~l~~~~~~~~g~fN~s~ll~~~~s~~~~~~~RSaIED 918 (1322)
1597 T 6NZK_A 839 SQLVEYGSFCDNINAILTEVNELLDTTQLQVANSLMNGVTLSTKLKDGVNFNVDDINFSPVLGCLGSECSKASSRSAIED 918 (1322)
1598 T ss_dssp HHGGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCEEEGGGGTCCCCEETTEECTTTCCCCCC----CCSCCHHHH
1599 T ss_pred HHHHHHHHHHHHHHHHHHHHHHhccHHHHHHHHHHhcCccccccccccccCCCCCccccccccCCCCCCCcCccccHHHH
1600 Confidence 99999999999999999999999999999999999998876 444445 6899999999875 3578999999
1601
1602
1603 Q sp|P0DTC2|SPIK 821 LLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAM 900 (1273)
1604 Q Consensus 821 llfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfam 900 (1273)
1605 |||+||..+|.|+.+.|.+|.+...+|||+|||.|||+.||||++++||++.||++|++|....|||+ |..||||+
1606 T Consensus 919 LLFnKV~tsglG~~~~Yk~Ct~g~~i~DL~CAQyyNGImVLPpVvd~~~~amYTaSL~g~m~~gg~Ta----aaaIPFa~ 994 (1322)
1607 T 6NZK_A 919 LLFDKVKLSDVGFVEAYNNCTGGAEIRDLICVQSYKGIKVLPPLLSENQFSGYTLAATSASLFPPWTA----AAGVPFYL 994 (1322)
1608 T ss_dssp HHHHTCSSSHHHHHHHHHTTTTTCCTTCHHHHHHHTTEEEECCSSCHHHHHHHHHHHHHTTTSSSCGG----GTTCCHHH
1609 T ss_pred HHcceeeeCCcchHHHhHhccCCccHHHhhccceeCcEEEeCCCCCHHHHHHHHHHHHHHhhccCchh----cccCcchH
1610 Confidence 99999999999999999999999999999999999999999999999999999999999999999997 55689999
1611
1612
1613 Q sp|P0DTC2|SPIK 901 QMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDI 980 (1273)
1614 Q Consensus 901 qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndi 980 (1273)
1615 ||.||+||+|+||+||.||||+|||.||.||+.||+.++.|++||.|+|||||++++||++|++||+.|||||||.++||
1616 T Consensus 995 ~vq~RlN~v~lt~~VL~~NQk~iA~sFN~Ai~~iq~~f~tt~~AL~KiQ~VVN~q~~aL~~L~~qL~~nFgAISssI~DI 1074 (1322)
1617 T 6NZK_A 995 NVQYRINGLGVTMDVLSQNQKLIANAFNNALYAIQEGFDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISASLQEI 1074 (1322)
1618 T ss_dssp HHHHHHHTTTCCHHHHTTCHHHHHHHHHHHHHHHHHTTTSCCHHHHHHHHHHHHHHHHHHHHHGGGGCCTTSSCSCHHHH
1619 T ss_pred HHHHHhcccccchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHH
1620 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
1621
1622
1623 Q sp|P0DTC2|SPIK 981 LSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGV 1060 (1273)
1624 Q Consensus 981 lsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgv 1060 (1273)
1625 ++|||++||++||||||+|||.+|++||+|||+|++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+||.||+|+
1626 T Consensus 1075 y~RLD~LEAdaQVDRLItGRL~aLNafVtQ~L~~~~eVr~sr~LA~qKINECVKSQS~R~gFCGnG~Hi~Si~q~AP~Gi 1154 (1322)
1627 T 6NZK_A 1075 LSRLDALEAEAQIDRLINGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAPYGL 1154 (1322)
1628 T ss_dssp HHHSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCSCCCSCCSSSTTSSEEEEEEEEETTEE
1629 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcccccCCCCCCeeEEEeeeccCCeE
1630 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
1631
1632
1633 Q sp|P0DTC2|SPIK 1061 VFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYD 1139 (1273)
1634 Q Consensus 1061 vflhvtyvpaqeknfttapaichdg-kahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvyd 1139 (1273)
1635 +|+|.+|+|.+.++.+++|.+|++| ++..|++|+|+.+...|++|.|++|+|..||.+|...-..|||...-+|+++..
1636 T Consensus 1155 ~F~H~~~~Pt~~~~V~a~~GlC~~~~~~~~~~~g~f~~~n~~~~~T~r~~y~Pr~~t~~d~v~~~sC~v~y~n~~~~~l~ 1234 (1322)
1637 T 6NZK_A 1155 YFIHFSYVPTKYVTARVSPGLCIAGDRGIAPKSGYFVNVNNTWMYTGSGYYYPEPITENNVVVMSTCAVNYTKAPYVMLN 1234 (1322)
1638 T ss_dssp EEEEEEEEEEEEEEEEEESCEECTTSCEEEESSEEEEEETTEEEEEESSSCCEEECCGGGEEEESSCCTTSEECTTCCCC
1639 T ss_pred EEEEeEecccceEEEEEeeeEEecCCeeEEecceEEEeeCCEEEEeccCcccCCCCCccceEEeccceeEEEEcCcccCC
1640 Confidence 9999999999999999999999995 899999999999988999999999999999999999999999999999999999
1641
1642
1643 Q sp|P0DTC2|SPIK 1140 PLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNI-QKEIDRLNEVAKNLNESLIDLQELG 1204 (1273)
1644 Q Consensus 1140 plqpeldsfkeeldkyfknhtspdvdlgdisginasvvni-qkeidrlnevaknlneslidlqelg 1204 (1273)
1645 |..|++..|+|||+|+|||+++...|+.. .-+|++++|+ ++||++|++++|+|+..-.+||.+-
1646 T Consensus 1235 ~~~p~~~df~~el~~~~~n~~~~~p~~~~-~~~N~t~Lnlt~~Ei~~L~~~~~~L~~~~~el~~~I 1299 (1322)
1647 T 6NZK_A 1235 TSIPNLPDFKEELDQWFKNQTSVAPDLSL-DYINVTFLDLLIKRMKQIEDKIEEIESKQKKIENEI 1299 (1322)
1648 T ss_dssp ------------------------------------------------------------------
1649 T ss_pred CCCCCCCChHHHHHHHHhcCCCCCCCCCc-cccccceecccHHHHHHHHHHHHHHHHHHHHHHHHH
1650 Confidence 99999999999999999999985555543 2299999999 6999999999999999888887654
1651
1652
1653 No 10
1654 >6M15_A Spike glycoprotein; VIRAL PROTEIN; HET: BMA, NAG; 2.38A {Rhinolophus bat coronavirus HKU2}
1655 Probab=100.00 E-value=6.1e-154 Score=1294.04 Aligned_cols=832 Identities=28% Similarity=0.472 Sum_probs=633.8 Template_Neff=3.500
1656
1657 Q sp|P0DTC2|SPIK 273 RTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYA 352 (1273)
1658 Q Consensus 273 rtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvya 352 (1273)
1659 -++||.|+.||+|+|++||+-+|++|-+|..++|....|.|..+++++ |+-..+|.+++ ..|+|..++||.. +++.
1660 T Consensus 216 s~~Ll~fDvNGtItdaIdC~~Sp~~eLaCsy~SFnfsdGVYpfSny~v-pkfiVYR~ssv-~nctFsN~snA~p--Si~~ 291 (1118)
1661 T 6M15_A 216 SSVLVLTDQSGAVTRYSYCADGFVNGLQCKLRLFDIPPGVYSNSEVEY-PVALYTVVHNM-SVCPQRPESYCGS--NYCP 291 (1118)
1662 T ss_dssp EEEEEEECTTSCEEEEEETTSSHHHHHHHHHTCSSCCSEEEEEEECCC-CEEEESCCSCC-EECCCCCCCCCCS--SCCC
1663 T ss_pred eeeeeeecCCCcEEEEEeccCCcccccceEeccccCCCceeccCCcee-ceEEEEEecCc-ceeecCHHhcCCC--Cccc
1664 Confidence 468999999999999999999999999999999999999999999999 99888998888 8899999999988 9999
1665
1666
1667 Q sp|P0DTC2|SPIK 353 WNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYN-YKLPDDFTG 431 (1273)
1668 Q Consensus 353 wnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadyn-yklpddftg 431 (1273)
1669 |.|+.++||..|+|.|. .+-+..|| |.+|.
1670 T Consensus 292 wqR~tfsNCNFNFSfLs---------------------------------------------Sdfm~SYN~y~~P~---- 322 (1118)
1671 T 6M15_A 292 FKRVVFSNCVVNYTSWT---------------------------------------------SGLLRDYQHLVLPN---- 322 (1118)
1672 T ss_dssp CCEEEECSEECCGGGGS---------------------------------------------CSCHHHHGGGBCTT----
1673 T ss_pred cEEEEeeceeeeccEec---------------------------------------------CcchheeeeccCCC----
1674 Confidence 99999999999999988 12222333 33343
1675
1676
1677 Q sp|P0DTC2|SPIK 432 CVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEI------YQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGY 505 (1273)
1678 Q Consensus 432 cviawnsnnldskvggnynylyrlfrksnlkpferdistei------yqagstpcngvegfncyfplqsygfqptngvgy 505 (1273)
1679 | |- ++.+ .+-..|.++--.+.+-+- .....+-- |+-|...|-|+..-.|- .
1680 T Consensus 323 c----nF-nPet-Ngl~FNsl~g~Ckqsv~~--f~g~~tcCy~~VIS~~~gp~~ckG~~~geCg---------------~ 379 (1118)
1681 T 6M15_A 323 G----KF-NPFT-ECNGLNRIVDDCVTGFVL--RVGRGTAVNRTVITPYLKPNECFGWSWNDYQ---------------D 379 (1118)
1682 T ss_dssp S----CB-CSCS-EEESBCSSCCSEEECEEE--EEEEEECBTTBCCCCCCCTTEEEEEEEEETT---------------T
1683 T ss_pred C----CC-CCcc-CCcCCccccCCCccceEE--EecCceeeEEEEECCCCCCCccceeeecccc---------------c
1684 Confidence 1 10 0111 111111100000000000 00000000 01133334444433221 0
1685
1686
1687 Q sp|P0DTC2|SPIK 506 QPYRVVVLSFEL-L-HAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLE 583 (1273)
1688 Q Consensus 506 qpyrvvvlsfel-l-hapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtle 583 (1273)
1689 -|-..+.| - -.++|+|.. ..++++.++||++|..|.+|+||++++|..+..+|.+..+-.| ..++++ +++
1690 T Consensus 380 ----~Vyv~~~~~g~S~~aTvCPv-d~tnI~Ld~CVdYNIYG~tGqGVItnsn~~~~~~q~GLy~ts~-L~~vk~--tg~ 451 (1118)
1691 T 6M15_A 380 ----SIYDWWIADFVSTGAFVCEK-NPDAPRTGVCITYTIEKVTFQGVLYESNFTFAQYYNVLYFGSQ-LKYVRI--LGK 451 (1118)
1692 T ss_dssp ----TEEEEEEEECCCCSCEEESS-CCCCCCTTSEEEEEETTEEEEEEEEECCCCCCTTCSEEEETTE-EEEEEE--TTE
1693 T ss_pred ----eEEeEeecCCccCCcccCCC-CCCCCccCeeEeEEeCCceeeEEEEEcCccceehhceEEEeee-eEEEEe--CCc
1694 Confidence 22333333 1 356899988 6689999999999999999999999999988888888777444 467777 999
1695
1696
1697 Q sp|P0DTC2|SPIK 584 ILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNN--SYE 661 (1273)
1698 Q Consensus 584 ilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnn--sye 661 (1273)
1699 +..|+||..+.++++..| ++.++.|++.+||.++.+..+.. +.||-.++. -|||-.||++++...++ ..+
1700 T Consensus 452 ~Y~V~PC~~v~qQvVv~~---~~~vglLt~S~ncn~~~~~~~~~---~~r~~~~~~--~fdt~~Gcv~~~~n~~~~~~~~ 523 (1118)
1701 T 6M15_A 452 VYEVAPCFEASYDVLFRS---SSSFGLLYRSFDCNQLRISASRF---AERLLPSHN--GTATALGCLFNATYAPNDTMVN 523 (1118)
1702 T ss_dssp EEEEECCTTSEEEEEEEE---TTEEEEEETTCCCCHHHHTSSTT---TTTCCGGGC--SEEETTEEEESSEEEEEEEESS
1703 T ss_pred EEEEecCcccceeEEEeC---CCeEEEEEcccccceeeeecccc---ccccCCCCC--CcccceeeEEEeecCCCCCCcc
1704 Confidence 999999999999999988 47899999999998887655544 334443333 39999999999987744 699
1705
1706
1707 Q sp|P0DTC2|SPIK 662 CDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMY 741 (1273)
1708 Q Consensus 662 cdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmy 741 (1273)
1709 |+.|+|.|||+.+ .-.-.+||.+-+ .+. ... .+.....+.|.||+||||+|++|-++++|.|.+|||.+|
1710 T Consensus 524 C~~p~g~giC~dg-~~~~~~r~~~l~------~~~-~~~--v~p~~~~~~IsIPtNFTlsvt~EYIQt~~~kVsVDCa~Y 593 (1118)
1711 T 6M15_A 524 CTNPLGDGFCADL-LSNVVVRRMTFE------KHD-TTY--VAPVTNERFTELPLDHQLVLTEQFLQTTMPKFSISCETY 593 (1118)
1712 T ss_dssp CSSEEETTEEEEC-SSSCEEEEECCC------CBC-CSC--CCCCCSSEEEEEEEEEEEEEEEEEEECCCCEEEECHHHH
1713 T ss_pred CCCCceeeEecCC-cceeceeeeeee------ccc-ccc--ccCcccceeEEccCceEeEEEEEEEeccCCCeEEecchh
1714 Confidence 9999999999999 333334432222 221 111 122334477899999999999999999999999999999
1715
1716
1717 Q sp|P0DTC2|SPIK 742 ICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQI-LPDPS----KPSKRS 816 (1273)
1718 Q Consensus 742 icgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqi-lpdps----kpskrs 816 (1273)
1719 +||++.+|.+||.|||+||..+|+||.+.+..+|.+..+++..+|..... +....|+||||++ +|..+ ++++||
1720 T Consensus 594 VCngn~~C~~LL~QYgs~C~~I~~aL~~~a~led~~~~~~~s~~~~~~~~-~~~~~~~FN~S~~~lp~~~~~~~~~~~RS 672 (1118)
1721 T 6M15_A 594 ICDVSKACKNLLFRYGGFCQKIEADIRGAGVLLDSDVSGLYSTIAAKTSS-ITPTTDRFNVSQFFLPKVQSNSERFESRS 672 (1118)
1722 T ss_dssp HSSSCHHHHTTGGGSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHBBCCCS-SCCBCSSCCCTTTTSCCCCCSSSCCCCCC
1723 T ss_pred ccCCCHHHHHHHHHHHHHHHHHHHHHHHHHHhhhHHHHHHHHHHhhhccC-cCCCCCCccccccccCCCCCCCccccccc
1724 Confidence 99999999999999999999999999999999999999999888766433 3366888999998 67654 346899
1725
1726
1727 Q sp|P0DTC2|SPIK 817 FIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGA--GAAL 894 (1273)
1728 Q Consensus 817 fiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfga--gaal 894 (1273)
1729 +||||||+||..+|.|+.+.|.+|.+ -.+|||+|||.+||+.||||++++||++.|| +.++.||+||+ ++|.
1730 T Consensus 673 ~IEDLLF~KV~t~glG~~~~Yk~Ct~-~~i~DL~CaQyyNGimVLP~v~d~~~~amYT-----asl~ggm~~Ggit~sAa 746 (1118)
1731 T 6M15_A 673 VIEDLLFSKIETTGPGFYGDYYNCKK-NAIQDLTCAQYHNGILVIPPVMDAETLGMYG-----GIAAASLTLGIFGGQAG 746 (1118)
1732 T ss_dssp HHHHHHHHSSCCCCSSHHHHHHHHHH-HCCTTCCCCCEETTEEEECCSSCGGGCCTTS-----STTCBCSSTTTTCSSCC
1733 T ss_pred HHHHHhccceEecCCCchHhHHHhhc-chhhHHhcccccCcEEEcCCCCCHHHHHHHH-----HHHHHHHHhhhhcchhc
1734 Confidence 99999999999999999999999999 6799999999999999999999999999999 44566899988 6789
1735
1736
1737 Q sp|P0DTC2|SPIK 895 QIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAIS 974 (1273)
1738 Q Consensus 895 qipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgais 974 (1273)
1739 .|||||||.||+||+|+||+||.||||+|||.||.|++.||+.++.+++||.|+|||||++++||++|++||+.||||||
1740 T Consensus 747 aiPFa~~vq~RlN~valt~~VL~~NQk~iA~sFN~A~~~iq~~f~tt~~AL~KIQ~VVN~q~~aL~~L~~QL~nnFgAIS 826 (1118)
1741 T 6M15_A 747 ITTWSLAMAGRLNALGVVQNALVDDVNKLANGFNQLTASVGKLALTTSSALQAIQAVVNQNAAQVESLVSGITENFGAIS 826 (1118)
1742 T ss_dssp CCBHHHHHHHHHHHTTSCSSCCHHHHHHHHHHHHHHHHTGGGCCTTTCHHHHHHHHHHHHHHHHHHHHHHTTTSCTTSSC
1743 T ss_pred hhhHHHHHHHHHhhhhhchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhHHH
1744 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
1745
1746
1747 Q sp|P0DTC2|SPIK 975 SVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQ 1054 (1273)
1748 Q Consensus 975 svlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpq 1054 (1273)
1749 |.++||++|||++||++||||||+|||.+|++||+|||+|++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+||
1750 T Consensus 827 SSI~dIy~RLD~leAdaQVDRLItGRL~aLnafVtq~l~~~~ev~~sr~LA~qKINECVKSQS~R~GFCGnGtHi~Si~q 906 (1118)
1751 T 6M15_A 827 TNFKVISQRLDKLEADVQMDRLINGRMNVLQLFVTNYKLKIAELRNTHRYVQSLINECVYAQSLRNGFCGQGLHVLSLMQ 906 (1118)
1752 T ss_dssp SCHHHHHHHBCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCSSCCCSTTTTSSSEEEEEEEE
1753 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccCcccCCCCCCeEeEeecc
1754 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
1755
1756
1757 Q sp|P0DTC2|SPIK 1055 SAPHGVVFLHVTYVPAQEKNFTTAPAICHD----GKAHFPREGVFVSNG-THWFVTQRNFYEPQIITTDNTFVSGNCDVV 1129 (1273)
1758 Q Consensus 1055 saphgvvflhvtyvpaqeknfttapaichd----gkahfpregvfvsng-thwfvtqrnfyepqiittdntfvsgncdvv 1129 (1273)
1759 .||+|++|+|.+|+|.+-++.+++|.+|++ +++..||+|+|+.+. +.|++|.|++|+|..||.+|.... .||+.
1760 T Consensus 907 ~APnGi~F~H~~y~Pt~~~~V~a~~GlC~~~~~~~~~~~~~~g~f~~~n~~~w~iT~r~my~Pr~it~~d~v~~-sc~v~ 985 (1118)
1761 T 6M15_A 907 NAPSGIMFFHYSLIPNNTITVKTTPGLCESDELGSKCIVAKDGVLVSANLSYWQWSPRNLYKPENLTFANVIAV-SRGAN 985 (1118)
1762 T ss_dssp EETTEEEEEEEEEEEEEEEEEEEESCEESSSSTTCCEEEESSSEEEESSCSSCEEECTTSCCCEECCTTTEEEE-CCCTT
1763 T ss_pred cCCCeEEEEEEEeccCceeEEEEeeeeEccCCCCCcEEEecccEEEEcCCCEEEECccccccCCCCCccCeEEE-ecCce
1764 Confidence 999999999999999999999999999999 457999999999864 999999999999999999998777 78999
1765
1766
1767 Q sp|P0DTC2|SPIK 1130 IGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQY 1209 (1273)
1768 Q Consensus 1130 igivnntvydplqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqy 1209 (1273)
1769 ...+|.++..|..|++-.|+|||+|+|||+++.-.||.+.+ +|++++|++.||++|+|+.|+||+++|||++|++||+|
1770 T Consensus 986 y~~vn~t~~~p~ipd~~Df~eel~e~~kn~s~~~pdl~~~~-~N~T~LNLs~EI~~LqevIk~LN~s~IdLe~L~~~e~Y 1064 (1118)
1771 T 6M15_A 986 YTTLNRTFDIPELNSTFPIDEEFREYFQNMSSELQALKNLT-ADMSKLNISAEIQLINEIAHNVSNMRVEVEKFQRYVNY 1064 (1118)
1772 T ss_dssp CEECSSCCCC----------------------------------------------------------------------
1773 T ss_pred EEEeccccCCCCCcCCCChHHHHHHHHhhcCccccccccce-ecCceechHHHHHHHHHHHHHHHhccccHHHhCeeeEE
1774 Confidence 99999999999999999999999999999988777787766 99999999999999999999999999999999999999
1775
1776
1777 Q sp|P0DTC2|SPIK 1210 IKWPWY 1215 (1273)
1778 Q Consensus 1210 ikwpwy 1215 (1273)
1779 |||.-.
1780 T Consensus 1065 iKW~~~ 1070 (1118)
1781 T 6M15_A 1065 VKLEVL 1070 (1118)
1782 T ss_dssp ------
1783 T ss_pred eeceee
1784 Confidence 999854
1785
1786
1787 No 11
1788 >6M15_B Spike glycoprotein; VIRAL PROTEIN; HET: NAG, BMA; 2.38A {Rhinolophus bat coronavirus HKU2}
1789 Probab=100.00 E-value=6.1e-154 Score=1294.04 Aligned_cols=832 Identities=28% Similarity=0.472 Sum_probs=633.8 Template_Neff=3.500
1790
1791 Q sp|P0DTC2|SPIK 273 RTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYA 352 (1273)
1792 Q Consensus 273 rtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvya 352 (1273)
1793 -++||.|+.||+|+|++||+-+|++|-+|..++|....|.|..+++++ |+-..+|.+++ ..|+|..++||.. +++.
1794 T Consensus 216 s~~Ll~fDvNGtItdaIdC~~Sp~~eLaCsy~SFnfsdGVYpfSny~v-pkfiVYR~ssv-~nctFsN~snA~p--Si~~ 291 (1118)
1795 T 6M15_B 216 SSVLVLTDQSGAVTRYSYCADGFVNGLQCKLRLFDIPPGVYSNSEVEY-PVALYTVVHNM-SVCPQRPESYCGS--NYCP 291 (1118)
1796 T ss_dssp EEEEEEECTTSCEEEEEETTSSHHHHHHHHHTCSSCCSEEEEEEECCC-CEEEESCCSCC-EECCCCCCCCCCS--SCCC
1797 T ss_pred eeeeeeecCCCcEEEEEeccCCcccccceEeccccCCCceeccCCcee-ceEEEEEecCc-ceeecCHHhcCCC--Cccc
1798 Confidence 468999999999999999999999999999999999999999999999 99888998888 8899999999988 9999
1799
1800
1801 Q sp|P0DTC2|SPIK 353 WNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYN-YKLPDDFTG 431 (1273)
1802 Q Consensus 353 wnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadyn-yklpddftg 431 (1273)
1803 |.|+.++||..|+|.|. .+-+..|| |.+|.
1804 T Consensus 292 wqR~tfsNCNFNFSfLs---------------------------------------------Sdfm~SYN~y~~P~---- 322 (1118)
1805 T 6M15_B 292 FKRVVFSNCVVNYTSWT---------------------------------------------SGLLRDYQHLVLPN---- 322 (1118)
1806 T ss_dssp CCEEEECSEECCGGGGS---------------------------------------------CSCHHHHGGGBCTT----
1807 T ss_pred cEEEEeeceeeeccEec---------------------------------------------CcchheeeeccCCC----
1808 Confidence 99999999999999988 12222333 33343
1809
1810
1811 Q sp|P0DTC2|SPIK 432 CVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEI------YQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGY 505 (1273)
1812 Q Consensus 432 cviawnsnnldskvggnynylyrlfrksnlkpferdistei------yqagstpcngvegfncyfplqsygfqptngvgy 505 (1273)
1813 | |- ++.+ .+-..|.++--.+.+-+- .....+-- |+-|...|-|+..-.|- .
1814 T Consensus 323 c----nF-nPet-Ngl~FNsl~g~Ckqsv~~--f~g~~tcCy~~VIS~~~gp~~ckG~~~geCg---------------~ 379 (1118)
1815 T 6M15_B 323 G----KF-NPFT-ECNGLNRIVDDCVTGFVL--RVGRGTAVNRTVITPYLKPNECFGWSWNDYQ---------------D 379 (1118)
1816 T ss_dssp S----CB-CSCS-EEESBCSSCCSEEECEEE--EEEEEECBTTBCCCCCCCTTEEEEEEEEETT---------------T
1817 T ss_pred C----CC-CCcc-CCcCCccccCCCccceEE--EecCceeeEEEEECCCCCCCccceeeecccc---------------c
1818 Confidence 1 10 0111 111111100000000000 00000000 01133334444433221 0
1819
1820
1821 Q sp|P0DTC2|SPIK 506 QPYRVVVLSFEL-L-HAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLE 583 (1273)
1822 Q Consensus 506 qpyrvvvlsfel-l-hapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtle 583 (1273)
1823 -|-..+.| - -.++|+|.. ..++++.++||++|..|.+|+||++++|..+..+|.+..+-.| ..++++ +++
1824 T Consensus 380 ----~Vyv~~~~~g~S~~aTvCPv-d~tnI~Ld~CVdYNIYG~tGqGVItnsn~~~~~~q~GLy~ts~-L~~vk~--tg~ 451 (1118)
1825 T 6M15_B 380 ----SIYDWWIADFVSTGAFVCEK-NPDAPRTGVCITYTIEKVTFQGVLYESNFTFAQYYNVLYFGSQ-LKYVRI--LGK 451 (1118)
1826 T ss_dssp ----TEEEEEEEECCCCSCEEESS-CCCCCCTTSEEEEEETTEEEEEEEEECCCCCCTTCSEEEETTE-EEEEEE--TTE
1827 T ss_pred ----eEEeEeecCCccCCcccCCC-CCCCCccCeeEeEEeCCceeeEEEEEcCccceehhceEEEeee-eEEEEe--CCc
1828 Confidence 22333333 1 356899988 6689999999999999999999999999988888888777444 467777 999
1829
1830
1831 Q sp|P0DTC2|SPIK 584 ILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNN--SYE 661 (1273)
1832 Q Consensus 584 ilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnn--sye 661 (1273)
1833 +..|+||..+.++++..| ++.++.|++.+||.++.+..+.. +.||-.++. -|||-.||++++...++ ..+
1834 T Consensus 452 ~Y~V~PC~~v~qQvVv~~---~~~vglLt~S~ncn~~~~~~~~~---~~r~~~~~~--~fdt~~Gcv~~~~n~~~~~~~~ 523 (1118)
1835 T 6M15_B 452 VYEVAPCFEASYDVLFRS---SSSFGLLYRSFDCNQLRISASRF---AERLLPSHN--GTATALGCLFNATYAPNDTMVN 523 (1118)
1836 T ss_dssp EEEEECCTTSEEEEEEEE---TTEEEEEETTCCCCHHHHTSSTT---TTTCCGGGC--SEEETTEEEESSEEEEEEEESS
1837 T ss_pred EEEEecCcccceeEEEeC---CCeEEEEEcccccceeeeecccc---ccccCCCCC--CcccceeeEEEeecCCCCCCcc
1838 Confidence 999999999999999988 47899999999998887655544 334443333 39999999999987744 699
1839
1840
1841 Q sp|P0DTC2|SPIK 662 CDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMY 741 (1273)
1842 Q Consensus 662 cdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmy 741 (1273)
1843 |+.|+|.|||+.+ .-.-.+||.+-+ .+. ... .+.....+.|.||+||||+|++|-++++|.|.+|||.+|
1844 T Consensus 524 C~~p~g~giC~dg-~~~~~~r~~~l~------~~~-~~~--v~p~~~~~~IsIPtNFTlsvt~EYIQt~~~kVsVDCa~Y 593 (1118)
1845 T 6M15_B 524 CTNPLGDGFCADL-LSNVVVRRMTFE------KHD-TTY--VAPVTNERFTELPLDHQLVLTEQFLQTTMPKFSISCETY 593 (1118)
1846 T ss_dssp CSSEEETTEEEEC-SSSCEEEEECCC------CBC-CSC--CCCCCSSEEEEEEEEEEEEEEEEEEECCCCEEEECHHHH
1847 T ss_pred CCCCceeeEecCC-cceeceeeeeee------ccc-ccc--ccCcccceeEEccCceEeEEEEEEEeccCCCeEEecchh
1848 Confidence 9999999999999 333334432222 221 111 122334477899999999999999999999999999999
1849
1850
1851 Q sp|P0DTC2|SPIK 742 ICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQI-LPDPS----KPSKRS 816 (1273)
1852 Q Consensus 742 icgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqi-lpdps----kpskrs 816 (1273)
1853 +||++.+|.+||.|||+||..+|+||.+.+..+|.+..+++..+|..... +....|+||||++ +|..+ ++++||
1854 T Consensus 594 VCngn~~C~~LL~QYgs~C~~I~~aL~~~a~led~~~~~~~s~~~~~~~~-~~~~~~~FN~S~~~lp~~~~~~~~~~~RS 672 (1118)
1855 T 6M15_B 594 ICDVSKACKNLLFRYGGFCQKIEADIRGAGVLLDSDVSGLYSTIAAKTSS-ITPTTDRFNVSQFFLPKVQSNSERFESRS 672 (1118)
1856 T ss_dssp HSSSCHHHHTTGGGSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHBBCCCS-SCCBCSSCCCTTTTSCCCCCSSSCCCCCC
1857 T ss_pred ccCCCHHHHHHHHHHHHHHHHHHHHHHHHHHhhhHHHHHHHHHHhhhccC-cCCCCCCccccccccCCCCCCCccccccc
1858 Confidence 99999999999999999999999999999999999999999888766433 3366888999998 67654 346899
1859
1860
1861 Q sp|P0DTC2|SPIK 817 FIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGA--GAAL 894 (1273)
1862 Q Consensus 817 fiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfga--gaal 894 (1273)
1863 +||||||+||..+|.|+.+.|.+|.+ -.+|||+|||.+||+.||||++++||++.|| +.++.||+||+ ++|.
1864 T Consensus 673 ~IEDLLF~KV~t~glG~~~~Yk~Ct~-~~i~DL~CaQyyNGimVLP~v~d~~~~amYT-----asl~ggm~~Ggit~sAa 746 (1118)
1865 T 6M15_B 673 VIEDLLFSKIETTGPGFYGDYYNCKK-NAIQDLTCAQYHNGILVIPPVMDAETLGMYG-----GIAAASLTLGIFGGQAG 746 (1118)
1866 T ss_dssp HHHHHHHHSSCCCCSSHHHHHHHHHH-HCCTTCCCCCEETTEEEECCSSCGGGCCTTS-----STTCBCSSTTTTCSSCC
1867 T ss_pred HHHHHhccceEecCCCchHhHHHhhc-chhhHHhcccccCcEEEcCCCCCHHHHHHHH-----HHHHHHHHhhhhcchhc
1868 Confidence 99999999999999999999999999 6799999999999999999999999999999 44566899988 6789
1869
1870
1871 Q sp|P0DTC2|SPIK 895 QIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAIS 974 (1273)
1872 Q Consensus 895 qipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgais 974 (1273)
1873 .|||||||.||+||+|+||+||.||||+|||.||.|++.||+.++.+++||.|+|||||++++||++|++||+.||||||
1874 T Consensus 747 aiPFa~~vq~RlN~valt~~VL~~NQk~iA~sFN~A~~~iq~~f~tt~~AL~KIQ~VVN~q~~aL~~L~~QL~nnFgAIS 826 (1118)
1875 T 6M15_B 747 ITTWSLAMAGRLNALGVVQNALVDDVNKLANGFNQLTASVGKLALTTSSALQAIQAVVNQNAAQVESLVSGITENFGAIS 826 (1118)
1876 T ss_dssp CCBHHHHHHHHHHHTTSCSSCCHHHHHHHHHHHHHHHHTGGGCCTTTCHHHHHHHHHHHHHHHHHHHHHHTTTSCTTSSC
1877 T ss_pred hhhHHHHHHHHHhhhhhchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhHHH
1878 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
1879
1880
1881 Q sp|P0DTC2|SPIK 975 SVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQ 1054 (1273)
1882 Q Consensus 975 svlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpq 1054 (1273)
1883 |.++||++|||++||++||||||+|||.+|++||+|||+|++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+||
1884 T Consensus 827 SSI~dIy~RLD~leAdaQVDRLItGRL~aLnafVtq~l~~~~ev~~sr~LA~qKINECVKSQS~R~GFCGnGtHi~Si~q 906 (1118)
1885 T 6M15_B 827 TNFKVISQRLDKLEADVQMDRLINGRMNVLQLFVTNYKLKIAELRNTHRYVQSLINECVYAQSLRNGFCGQGLHVLSLMQ 906 (1118)
1886 T ss_dssp SCHHHHHHHBCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCSSCCCSTTTTSSSEEEEEEEE
1887 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccCcccCCCCCCeEeEeecc
1888 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
1889
1890
1891 Q sp|P0DTC2|SPIK 1055 SAPHGVVFLHVTYVPAQEKNFTTAPAICHD----GKAHFPREGVFVSNG-THWFVTQRNFYEPQIITTDNTFVSGNCDVV 1129 (1273)
1892 Q Consensus 1055 saphgvvflhvtyvpaqeknfttapaichd----gkahfpregvfvsng-thwfvtqrnfyepqiittdntfvsgncdvv 1129 (1273)
1893 .||+|++|+|.+|+|.+-++.+++|.+|++ +++..||+|+|+.+. +.|++|.|++|+|..||.+|.... .||+.
1894 T Consensus 907 ~APnGi~F~H~~y~Pt~~~~V~a~~GlC~~~~~~~~~~~~~~g~f~~~n~~~w~iT~r~my~Pr~it~~d~v~~-sc~v~ 985 (1118)
1895 T 6M15_B 907 NAPSGIMFFHYSLIPNNTITVKTTPGLCESDELGSKCIVAKDGVLVSANLSYWQWSPRNLYKPENLTFANVIAV-SRGAN 985 (1118)
1896 T ss_dssp EETTEEEEEEEEEEEEEEEEEEEESCEESSSSTTCCEEEESSSEEEESSCSSCEEECTTSCCCEECCTTTEEEE-CCCTT
1897 T ss_pred cCCCeEEEEEEEeccCceeEEEEeeeeEccCCCCCcEEEecccEEEEcCCCEEEECccccccCCCCCccCeEEE-ecCce
1898 Confidence 999999999999999999999999999999 457999999999864 999999999999999999998777 78999
1899
1900
1901 Q sp|P0DTC2|SPIK 1130 IGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQY 1209 (1273)
1902 Q Consensus 1130 igivnntvydplqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqy 1209 (1273)
1903 ...+|.++..|..|++-.|+|||+|+|||+++.-.||.+.+ +|++++|++.||++|+|+.|+||+++|||++|++||+|
1904 T Consensus 986 y~~vn~t~~~p~ipd~~Df~eel~e~~kn~s~~~pdl~~~~-~N~T~LNLs~EI~~LqevIk~LN~s~IdLe~L~~~e~Y 1064 (1118)
1905 T 6M15_B 986 YTTLNRTFDIPELNSTFPIDEEFREYFQNMSSELQALKNLT-ADMSKLNISAEIQLINEIAHNVSNMRVEVEKFQRYVNY 1064 (1118)
1906 T ss_dssp CEECSSCCCC----------------------------------------------------------------------
1907 T ss_pred EEEeccccCCCCCcCCCChHHHHHHHHhhcCccccccccce-ecCceechHHHHHHHHHHHHHHHhccccHHHhCeeeEE
1908 Confidence 99999999999999999999999999999988777787766 99999999999999999999999999999999999999
1909
1910
1911 Q sp|P0DTC2|SPIK 1210 IKWPWY 1215 (1273)
1912 Q Consensus 1210 ikwpwy 1215 (1273)
1913 |||.-.
1914 T Consensus 1065 iKW~~~ 1070 (1118)
1915 T 6M15_B 1065 VKLEVL 1070 (1118)
1916 T ss_dssp ------
1917 T ss_pred eeceee
1918 Confidence 999854
1919
1920
1921 No 12
1922 >6JX7_A Feline Infectious Peritonitis Virus Spike; CoV spike protein, VIRAL PROTEIN; HET: NAG, MAN, FUC, BMA; 3.31A {Feline infectious peritonitis virus}
1923 Probab=100.00 E-value=2e-132 Score=1149.25 Aligned_cols=664 Identities=33% Similarity=0.532 Sum_probs=532.7 Template_Neff=4.600
1924
1925 Q sp|P0DTC2|SPIK 525 CGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTN- 603 (1273)
1926 Q Consensus 525 cgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitpgtn- 603 (1273)
1927 -|-...++++.++||++|.-|.+|+|++++++..+... .+-.|...-.++.++..++++..|+||....++|+..|+.
1928 T Consensus 674 ~g~~d~~~i~l~~Cv~YnIYG~tG~GvI~~~~~~~~~G-l~~~s~sG~l~~Fk~~~~~~~Y~V~PC~~~~Q~vV~~~~iV 752 (1468)
1929 T 6JX7_A 674 LGFQDISNIVKDECTDYNIYGFQGTGIIRSTTSRLVAG-LYYTSASGDLLGFKISTTGEIFTVVPCDLTAQAAVINDEIV 752 (1468)
1930 T ss_dssp CSCSSCCCCCBSSEEEEEETTEEEEEEEEECCCCCCSC-SEEECTTSCEEEEECSSSSCEEEEECSSCCEEEEESSSSEE
1931 T ss_pred ceeeccceeEeccceeEEeCCccceEEEEecCeeeeCc-EEEEcCCCCEEEEEeCCCCCEEEEEeCCcCceEEEECCeEE
1932 Confidence 34456789999999999999999999999999888655 6667777778999999999999999999999999999875
1933
1934
1935 Q sp|P0DTC2|SPIK 604 ---TSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNS 680 (1273)
1936 Q Consensus 604 ---tsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsyecdipigagicasyqtqtns 680 (1273)
1937 ||...+.+++.+||+++..+.+ .++. ..+.++|-.||.+++.+...+.+|+.++|.|.|+-+.+-.
1938 T Consensus 753 G~ltS~n~~~~~~~~nct~v~~s~~---s~~~------~~~~~~TP~fcy~~~~~~~~~~~c~~~l~yg~~~i~~dG~-- 821 (1468)
1939 T 6JX7_A 753 GAITATNQTDLFEFVNHTWSRSARG---SSPS------TVNTYTMPQFYYITKWNNGTSSNCTSVITYSSFAICNTGE-- 821 (1468)
1940 T ss_dssp EEEESSSCCCSSSCSCC--------------C------CCCEEECSSCEEECSCCSSSCCCCCCCBCCTTEEECTTSC--
1941 T ss_pred EEEEccCcccccccceeeeeeeecc---CCCC------cccceecceeEEEeeccCCccccccceeeeceEEEcCCCc--
1942 Confidence 7788889999999999884433 1111 3455999999999999888899999999999888776621
1943
1944
1945 Q sp|P0DTC2|SPIK 681 PRRARSVASQSIIAYTMSLGAE-NS--VAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYG 757 (1273)
1946 Q Consensus 681 prrarsvasqsiiaytmslgae-ns--vaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqyg 757 (1273)
1947 .+-+ -...+++... .. ..-....|.||+||||+|++|-+.++|.|.+|||.+|+||++.+|.+||.|||
1948 T Consensus 822 ---i~~v-----~~~~~~~~~~~~~~~~~~~t~~v~IP~nFt~~v~~EyiQ~~~~kv~idC~~YVC~~~~~C~~ll~qYg 893 (1468)
1949 T 6JX7_A 822 ---IKYV-----NVTHVEIVDDSVGVIKPVSTGNITIPKNFTVAVQAEYVQIQVKPVAVDCAKYVCNGNRHCLNLLTQYT 893 (1468)
1950 T ss_dssp ---EEEC-----CCEECSSSSCSSSSCCCCCSSEEECCCCEEEEEEEEEECCCCCCEEECHHHHHSSSCHHHHTTGGGGH
1951 T ss_pred ---EEEE-----eceeeeeeeCccccccceeEEEEEecCCeeEEEEEEEEeccCCceEEechhhhcCCCHHHHHHHHHHh
1952 Confidence 1111 0000111000 00 11123478999999999999999999999999999999999999999999999
1953
1954
1955 Q sp|P0DTC2|SPIK 758 SFCTQLNRALTGIAVEQDKNTQEVFAQVKQ-IYKTPPIKDFG-------------GFNFSQILPDPSKPSKRSFIEDLLF 823 (1273)
1956 Q Consensus 758 sfctqlnraltgiaveqdkntqevfaqvkq-iyktppikdfg-------------gfnfsqilpdpskpskrsfiedllf 823 (1273)
1957 +||..+++||.+.+ .+|......+..+.. -++++-+.+|. ++|++.+||.+. ++||+||||||
1958 T Consensus 894 s~C~~I~~al~~~~-~ld~~~~~~~~~~~~~~~~~~~~~~fn~~~~~~~~~g~~~~~~~s~~l~~~~--~~RS~IEDLLF 970 (1468)
1959 T 6JX7_A 894 SACQTIENSLNLGA-RLESLMLNDMITVSDRSLEFATVDKFNTTALGGEKLGGLYFDGLSSLLPPRV--GMRSAVEDLLF 970 (1468)
1960 T ss_dssp HHHHHHHHHHHHHH-HHHHHHHTTTCEECHHHHTTCSTTTTTSCCSSSCCSSCTTHHHHHHHSCSSS--SSCCHHHHHHT
1961 T ss_pred HHHHHHHHHHHHHH-HHHHHhHhhcceeccccccccCcccccCcccCcccccccccCCcccCCCCCC--CCCcHHHHHhc
1962 Confidence 99999999999988 666443334444332 44555565553 267787787654 79999999999
1963
1964
1965 Q sp|P0DTC2|SPIK 824 NKVTLADAGFIK-QYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQM 902 (1273)
1966 Q Consensus 824 nkvtladagfik-qygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqm 902 (1273)
1967 +||..+|.|+++ .|.+|.+...+|||+|||.+||+.||||++++||++.||++|++|....|||. |..||||+||
1968 T Consensus 971 ~KV~t~glg~vd~~Y~~C~~g~~i~DL~CaQ~yNGi~VLP~v~~~~~~a~YT~sl~g~m~~gg~t~----aaaiPFa~~v 1046 (1468)
1969 T 6JX7_A 971 NKVVTSGLGTVDDDYKKCSAGTDVADLVCAQYYNGIMVLPGVVDYNKMAMYTASLIGGMALGSITS----AVAVPFSMQV 1046 (1468)
1970 T ss_dssp TTTTTTTCCCCCCCSTTTTTCSSSCCHHHHHHHTTEEECCCSSCHHHHHHHHHHHHHHHHCCCTTC----CCCCCHHHHH
1971 T ss_pred ccEEecCCCcCCHHHHHccCCccHHHHhCccccCeEEEeCCCCCHHHHHHHHHHHHHHHHhcchhh----eecccHHHHH
1972 Confidence 999999999999 69999999999999999999999999999999999999999999999999996 6679999999
1973
1974
1975 Q sp|P0DTC2|SPIK 903 AYRFNGIGVTQNVLYENQKLIANQFNSAIGKI--------------QDSLSSTASALGKLQDVVNQNAQALNTLVKQLSS 968 (1273)
1976 Q Consensus 903 ayrfngigvtqnvlyenqklianqfnsaigki--------------qdslsstasalgklqdvvnqnaqalntlvkqlss 968 (1273)
1977 .+|+|++|+||+||.||||+|||.||.|||.| |+.++++++||.|+|||||++++||++|++||+.
1978 T Consensus 1047 q~RlN~v~lt~~vL~~NQk~iA~sFN~A~~~it~af~~v~~ai~~t~~gf~t~~~Al~kiQ~VVN~q~~aL~~l~~qL~~ 1126 (1468)
1979 T 6JX7_A 1047 QARLNYVALQTDVLQENQKILANAFNNAIGNITLALGKVSNAITTVSDGFNSMASALTKIQSVVNQQGEALSHLISQLQK 1126 (1468)
1980 T ss_dssp HHHHHTTSCCCSCCHHHHHHHHHHHHHHHHHHHHHHHSCCSCSCCCCSHHHHHHHHHHHHHHHTTTHHHHHHHHHGGGSC
1981 T ss_pred HHHhhhhhhchHHHHHHHHHHHHHHHHHHHHHHHHhhhhhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
1982 Confidence 99999999999999999999999999999999 6668999999999999999999999999999999
1983
1984
1985 Q sp|P0DTC2|SPIK 969 NFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYH 1048 (1273)
1986 Q Consensus 969 nfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyh 1048 (1273)
1987 |||||||.++||.+|||++||++|+||||+|||.+|++||+|+|+|++|+|+|+.||..|+.|||..||+|.+|||.|.|
1988 T Consensus 1127 nFgAISssi~dIy~rLd~leAdaQvDRLItGRL~aLna~vtq~l~~~~~v~~sr~LA~qKinECVksQS~R~gFCGnG~H 1206 (1468)
1989 T 6JX7_A 1127 NFQAISSSIAEIYNRLEKVEADAQVDRLITGRLAALNAYVAQTLTQYAEVKASRQLAMEKVNECVKSQSDRYGFCGNGTH 1206 (1468)
1990 T ss_dssp CTTSSCSCHHHHTTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCTTCCCCTTSSSSSSE
1991 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccCCCCCCee
1992 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
1993
1994
1995 Q sp|P0DTC2|SPIK 1049 LMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPRE--GVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGN 1125 (1273)
1996 Q Consensus 1049 lmsfpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpre--gvfvsngthwfvtqrnfyepqiittdntfvsgn 1125 (1273)
1997 ++|+||.||.|++|+|.+|+|.+-++.+++|.+|+++ ++..||+ ++|+.+...|++|.|++|||..||.+|...-..
1998 T Consensus 1207 v~S~~q~APnGi~F~H~~~~Pt~~~~v~a~~GlC~~~~~~~~~~~~~~~~~~~n~~~~~T~r~~y~Pr~~t~~d~v~~~s 1286 (1468)
1999 T 6JX7_A 1207 LFSLVNSAPDGLLFFHTVLLPTEWEEVTAWSGICVNDTYAYLLKDFDHSIFSYNGTYMVTPRNMFQPRKPQMSDFVQITS 1286 (1468)
2000 T ss_dssp EEEEEEEETTEEEEEEEEEEECCCCEEECBSCEEETTTEEEEESSSSEEEEESSSCEEEEESSSCCCBCCCGGGEEEESC
2001 T ss_pred eEeeeecCCCeEEEEEEEeccCceEEEEEEEEEeecCCeeEEeecCceEEEeeCCEEEEeccccccCCCCCccceEEeec
2002 Confidence 9999999999999999999999999999999999995 7889998 999998889999999999999999999999999
2003
2004
2005 Q sp|P0DTC2|SPIK 1126 CDVVIGIVNNTVYDPLQPEL----DSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRL--------------N 1187 (1273)
2006 Q Consensus 1126 cdvvigivnntvydplqpel----dsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrl--------------n 1187 (1273)
2007 |||...-++.++..+..|++ +.|+|||++++|||++|+.++.. ..+|+++.||+.||++| +
2008 T Consensus 1287 C~v~y~n~~~~~~~~~~p~~~d~n~~~~~~~~~~~~n~t~~~~~~~~-~~~n~t~Lnl~~Ei~~l~~~~~~l~~~~~~~~ 1365 (1468)
2009 T 6JX7_A 1287 CEVTFLNTTHTTFQEIVIDYIDINKTIADMLEQYHSNYTTPELDLQL-EIFNQTKLNLTAEIDQLEQRADNLTNIAHELQ 1365 (1468)
2010 T ss_dssp CCTTSEEECHHHHHHHSTTCCCHHHHHHHHHHHHTC--------------------------------------------
2011 T ss_pred CeeEEEEcccccccccccCccccCHhHHHHHHHhcCCCCCcccccCc-cccccceecHHHHHHHHHHHHHHHHHHHHHHH
2012 Confidence 99999999999999999999 99999999999999999997765 88999999999999997 9
2013
2014
2015 Q sp|P0DTC2|SPIK 1188 EVAKNLNESLIDLQELGKYEQYIKWPWYI 1216 (1273)
2016 Q Consensus 1188 evaknlneslidlqelgkyeqyikwpwyi 1216 (1273)
2017 |+.|+||+++|||++|++||+||||||.-
2018 T Consensus 1366 ~~i~~lN~s~idLe~L~~~e~YiKWPW~~ 1394 (1468)
2019 T 6JX7_A 1366 QYIDNLNKTIVDLEWLNRIETYVKWPGSG 1394 (1468)
2020 T ss_dssp -----------------------------
2021 T ss_pred HHHHHHHhcCccHHHHceeEeEecCcccc
2022 Confidence 99999999999999999999999999963
2023
2024
2025 No 13
2026 >5SZS_A Spike glycoprotein; coronavirus, viral fusion protein, vaccine; HET: MAN, NAG, BMA; 3.4A {Human coronavirus NL63}
2027 Probab=100.00 E-value=7.1e-131 Score=1128.95 Aligned_cols=662 Identities=31% Similarity=0.515 Sum_probs=529.3 Template_Neff=4.500
2028
2029 Q sp|P0DTC2|SPIK 505 YQPYRVVVLSFE----LLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQ 580 (1273)
2030 Q Consensus 505 yqpyrvvvlsfe----llhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpq 580 (1273)
2031 ++.+..|-+++. ...+|..+.|-...+++..++||++|.-|.+|+|++++++..+...+.+ .+.+.-..++++..
2032 T Consensus 575 ~~~~~~VYVt~s~GsrItgv~~p~~g~~d~~~i~l~~CvdYnIYG~tG~GvI~n~n~~~~~Gl~~-tS~sg~l~~fk~~~ 653 (1325)
2033 T 5SZS_A 575 YTIVGALYVTWSEGNSITGVPYPVSGIREFSNLVLNNCTKYNIYDYVGTGIIRSSNQSLAGGITY-VSNSGNLLGFKNVS 653 (1325)
2034 T ss_dssp EEEEEEEEECCEEEEEEEECSSCCCSCSSCCBCCCSSCEEEEETTEEEEEEEEEECCCCCSCSEE-ECTTSCEEEEECTT
2035 T ss_pred EEEEEEEEEEecCCCeeEcccccccceeccceEEeCeeeeeEeCCccceeEEEeeceeeeCCEEE-EcCCCCEEEEEcCC
2036 Confidence 666677777765 5556666888888999999999999999999999999999999888888 78888888999999
2037
2038
2039 Q sp|P0DTC2|SPIK 581 TLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAG-CLIGAEHVNN- 658 (1273)
2040 Q Consensus 581 tleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtrag-cligaehvnn- 658 (1273)
2041 ++++..|+||..+.++|+..|+. ..+.+ ..|++.-+ ..|.|+|-.| |..++++.-+
2042 T Consensus 654 ~g~~Y~V~PC~~~~Q~VV~~g~~---vGalt--s~n~~~~~-----------------fnn~~~t~~~~~~s~~~~n~t~ 711 (1325)
2043 T 5SZS_A 654 TGNIFIVTPCNQPDQVAVYQQSI---IGAMT--AVNESRYG-----------------LQNLLQLPNFYYVSNGGNNCTT 711 (1325)
2044 T ss_dssp SSCEEEEECSSCCEEEEEETTEE---EEEEE--SSSSCCSS-----------------CCEEEEETTEEEEESCCSCCSC
2045 T ss_pred CCCEEEEEeCCCCCeEEEECCce---eEEEE--ceeceecC-----------------CCcceecCCcEEEecCCcccCC
2046 Confidence 99999999999999999998762 22222 22222111 3467778888 7777644433
2047
2048
2049 Q sp|P0DTC2|SPIK 659 -SYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVD 737 (1273)
2050 Q Consensus 659 -syecdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvd 737 (1273)
2051 ..+| .|.|||+.+......|++. ....+ .. -....|.||+|||++|++|-++.+|.|.+||
2052 T Consensus 712 ~v~ty---~~~giC~dg~~~~~~~~~~---~~~~~--------~~----~~t~~i~IP~nft~~v~~EyiQ~~~~kv~iD 773 (1325)
2053 T 5SZS_A 712 AVMTY---SNFGICADGSLIPVRPRNS---SDNGI--------SA----IITANLSIPSNWTTSVQVEYLQITSTPIVVD 773 (1325)
2054 T ss_dssp EEEEE---TTEEEETTSCEEECCCCBC---CCCCC--------CC----SSSEEEEEEEEEEEEEEEEEEECCCCCEEEC
2055 T ss_pred cchhc---ccceEeeCCCccccccccC---CCCCc--------ee----ceeeeEEccCceEEEEEEEEeeccCCCeEEe
2056 Confidence 3455 8999999998775555321 11111 00 1112799999999999999999999999999
2057
2058
2059 Q sp|P0DTC2|SPIK 738 CTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVK---QIYKTPPIKDFGGFNFSQILPDPSKP-- 812 (1273)
2060 Q Consensus 738 ctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvk---qiyktppikdfggfnfsqilpdpskp-- 812 (1273)
2061 |.+|+||++.+|.+||.|||+||..+++||.+.+..++. |++..++ +.+..+.+..|++|||+.+||.+..+
2062 T Consensus 774 C~~YVC~~~~~C~~ll~qYgs~C~~I~~al~~~~~~~~~---~~~~~~~~~~~~~~~~~~~~~~~~n~s~~l~~~~~~~~ 850 (1325)
2063 T 5SZS_A 774 CATYVCNGNPRCKNLLKQYTSACKTIEDALRLSAHLETN---DVSSMLTFDSNAFSLANVTSFGDYNLSSVLPQRNIRSS 850 (1325)
2064 T ss_dssp TTTTTSTTCTTHHHHGGGGHHHHHHHHHHHHHHHHHHHH---HHHHHCCBCHHHHHHTCGGGTGGGCCTTTSCCSCCSSS
2065 T ss_pred chhhccCCCHHHHHHHHHHhHHHHHHHHHHHHHHHHhhH---HHHhhhccCCcccccccccccCCCcchhccCCCCCCCc
2066 Confidence 999999999999999999999999999999999988754 4444444 34455678999999999999998754
2067
2068
2069 Q sp|P0DTC2|SPIK 813 --SKRSFIEDLLFNKVTLADAGFIK-QYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFG 889 (1273)
2070 Q Consensus 813 --skrsfiedllfnkvtladagfik-qygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfg 889 (1273)
2071 +.||+||||||+||..+|.|+++ .|..|.+...+|||+|||.+||+.||||++++||+|.||++|++|....|||.
2072 T Consensus 851 ~~~~RS~IEDLLF~KV~t~glg~vd~~Y~~C~~g~~i~DL~CaQ~yNGi~VLP~v~~~~~~a~YT~sl~g~m~~gg~ta- 929 (1325)
2073 T 5SZS_A 851 RIAGRSALEDLLFSKVVTSGLGTVDVDYKSCTKGLSIADLACAQYYNGIMVLPGVADAERMAMYTGSLIGGMVLGGLTS- 929 (1325)
2074 T ss_dssp CSCCCCHHHHHHHHHHC-------CCCGGGGGSCSSCCCHHHHHHTTTEEECCCSSCHHHHHHHHHHHHHTTTCCSBST-
2075 T ss_pred ccCcccHHHHHHCCceeecCCCccchhhHHccCCccHHHHhcccccCeEEEeCCCCCHHHHHHHHHHHHHHHHhhchHH-
2076 Confidence 89999999999999999999997 99999999999999999999999999999999999999999999999999997
2077
2078
2079 Q sp|P0DTC2|SPIK 890 AGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDS--------------LSSTASALGKLQDVVNQN 955 (1273)
2080 Q Consensus 890 agaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqds--------------lsstasalgklqdvvnqn 955 (1273)
2081 |..||||+||.+|+||+|+||+||.||||+|||.||.|||.||.. ++++|+||.|+|||||++
2082 T Consensus 930 ---aaaiPFa~~vq~RlN~v~lt~~VL~~NQk~iA~sFN~A~~~i~~~f~~vn~ai~qts~~~~tv~~Al~kiQ~VVN~q 1006 (1325)
2083 T 5SZS_A 930 ---AAAIPFSLALQARLNYVALQTDVLQENQKILAASFNKAINNIVASFSSVNDAITQTAEAIHTVTIALNKIQDVVNQQ 1006 (1325)
2084 T ss_dssp ---TCCCCHHHHHHHHHHTTSCCCCSSCHHHHHHHHHHHHHHHHHHHHHHC--------CTHHHHHHHHHHHHHHHHHHH
2085 T ss_pred ---hhhChHHHHHHHHhhHhhhcHHHHHHHHHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHH
2086 Confidence 556899999999999999999999999999999999999999988 445669999999999999
2087
2088
2089 Q sp|P0DTC2|SPIK 956 AQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLG 1035 (1273)
2090 Q Consensus 956 aqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlg 1035 (1273)
2091 ++||++|++||+.|||||||.++||.+|||++||++|+||||+|||.+|++||+|+|.|++|+|+|+.||..|+.|||..
2092 T Consensus 1007 ~~aL~~l~~qL~~nFgAISssi~dIy~rLd~leAdaQvDRLItGRL~aLna~vtq~l~~~~~v~~sr~LA~qKinECVks 1086 (1325)
2093 T 5SZS_A 1007 GSALNHLTSQLRHNFQAISNSIQAIYDRLDSIQADQQVDRLITGRLAALNAFVSQVLNKYTEVRGSRRLAQQKINECVKS 1086 (1325)
2094 T ss_dssp HHHHHHHHHGGGCCCSSSCSCHHHHHTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
2095 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHc
2096 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
2097
2098
2099 Q sp|P0DTC2|SPIK 1036 QSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVS--NGTHWFVTQRNFYEP 1112 (1273)
2100 Q Consensus 1036 qskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregvfvs--ngthwfvtqrnfyep 1112 (1273)
2101 ||+|.+|||.|.|++|+||.||+|++|+|.+|+|.+-++.+++|.+|+++ ++..||++.|+- +...|++|.|++|||
2102 T Consensus 1087 QS~R~gFCGnG~Hi~S~~q~APnGi~F~H~~~~Pt~~~~v~a~~GlC~~~~~~~~~~~~~~v~~~~n~~~~~T~r~~y~P 1166 (1325)
2103 T 5SZS_A 1087 QSNRYGFCGNGTHIFSIVNSAPDGLLFLHTVLLPTDYKNVKAWSGICVDGIYGYVLRQPNLVLYSDNGVFRVTSRVMFQP 1166 (1325)
2104 T ss_dssp CCCCTTSSSSSEEEEEEEEEETTEEEEEEEEEEEEEEEEEEEESCEEETTTEEEEESSTTEEEEEETTEEEEEESSSCCC
2105 T ss_pred cCcCcCCCCCCeeeEEeeecCCCeEEEEEEeecccceeEEEEEEEEeecCCeeEEecCCCeEEEecCCEEEEeccccccC
2106 Confidence 99999999999999999999999999999999999999999999999995 789999996655 777999999999999
2107
2108
2109 Q sp|P0DTC2|SPIK 1113 QIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPD-VDLGDISGINASVVNIQKEIDR------ 1185 (1273)
2110 Q Consensus 1113 qiittdntfvsgncdvvigivnntvydplqpeldsfkeeldkyfknhtspd-vdlgdisginasvvniqkeidr------ 1185 (1273)
2111 ..||.++...-..|||...-++.++..+..|+.-.|++||+|+||++++.. .|+ ++..+|+.+.|+..||++
2112 T Consensus 1167 r~~t~~d~v~~~sc~v~y~n~~~~~~~~~~p~~~d~~~el~~~~~~~~~~~~p~~-~~~~~n~t~lnl~~ei~~L~~~~~ 1245 (1325)
2113 T 5SZS_A 1167 RLPVLSDFVQIYNCNVTFVNISRVELHTVIPDYVDVNKTLQEFAQNLPKYVKPNF-DLTPFNLTYLNLSSELKQLEAKTA 1245 (1325)
2114 T ss_dssp BCCCGGGEEECSCCCSSSEEECTTGGGGTSTTCCCHHHHHHHC-------------------------------------
2115 T ss_pred cCCCccceEEeeccceEEEEccceecCCCCCCCCChHHHHHHHHHcCCCCCCCCC-CcccccceecchHHHHHHHHHHHh
2116 Confidence 999999999999999999999999999999999999999999999987655 455 378899999999999999
2117
2118
2119 Q sp|P0DTC2|SPIK 1186 --------LNEVAKNLNESLIDLQELGKYEQYIKWPWY 1215 (1273)
2120 Q Consensus 1186 --------lnevaknlneslidlqelgkyeqyikwpwy 1215 (1273)
2121 |+++.|+||+++|||++|++||+||||---
2122 T Consensus 1246 ~l~~~~~~l~~~i~~lN~s~idLe~L~~~e~YiKW~~~ 1283 (1325)
2123 T 5SZS_A 1246 SLFQTTVELQGLIDQINSTYVDLKLLNRFENLIKRMKQ 1283 (1325)
2124 T ss_dssp --------------------------------------
2125 T ss_pred hHHHHHHHHHHHHHHHHHhccCHHHhcHHHHHHHHHHH
2126 Confidence 999999999999999999999999999643
2127
2128
2129 No 14
2130 >6IXB_B Spike glycoprotein; Alphacoronavirus, spike glycoprotein, STRUCTURAL PROTEIN; HET: MAN, NAG, BMA;{Human coronavirus 229E}
2131 Probab=100.00 E-value=8.3e-129 Score=1101.71 Aligned_cols=647 Identities=34% Similarity=0.594 Sum_probs=512.2 Template_Neff=4.700
2132
2133 Q sp|P0DTC2|SPIK 518 LHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSV 597 (1273)
2134 Q Consensus 518 lhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsv 597 (1273)
2135 ..+|..+.|-...++++.++||++|.-|.+|+|++++++..+...+.+ .|...-.++.++..++++..|+||....++|
2136 T Consensus 426 ~gv~~p~~~~~d~~~i~l~~Cv~YnIYG~tG~GvI~~~n~~~~~gl~~-~s~sG~l~~Fk~~~~g~~Y~V~PC~~~~q~V 504 (1116)
2137 T 6IXB_B 426 TGVPQPVEGVSSFMNVTLDKCTKYNIYDVSGVGVIRVSNDTFLNGITY-TSTSGNLLGFKDVTKGTIYSITPCNPPDQLV 504 (1116)
2138 T ss_dssp EECSSSCCCSCCCCCCCCSSCEEEEETTEEEEEEEEEECCCCCSCSEE-ECSSSCEEEEECTTTSCEEEEEESSCCEEEE
2139 T ss_pred EeecccccccccceeEEeCeeeeeEecCccceEEEEeeCceeeCcEEE-EeCCCCEEEEEcCCCCcEEEEeeCCCCCeEE
2140 Confidence 345555788888999999999999999999999999999999877777 7888888999999999999999999999999
2141
2142
2143 Q sp|P0DTC2|SPIK 598 ITPGTNTSNQVAVLYQDVNCTEVPV-AIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIP----IGAGICA 672 (1273)
2144 Q Consensus 598 itpgtntsnqvavlyqdvnctevpv-aihadqltptwrvystgsnvfqtragcligaehvnnsyecdip----igagica 672 (1273)
2145 +..| +...+.++.... .+... .+ .+|.+ +++. +| ...|.-| .|.|||+
2146 T Consensus 505 V~~~---~~vgalts~n~~-~~~~~~~~----~~~~~---------~~~~----~~------~~n~~~~~~~~~~~giC~ 557 (1116)
2147 T 6IXB_B 505 VYQQ---AVVGAMLSENFT-SYGFSNVV----ELPKF---------FYAS----NG------TYNCTDAVLTYSSFGVCA 557 (1116)
2148 T ss_dssp ECSS---SEEEEECSSCCC-CSSSSCCC----CCSSS---------CCBC----CS------CCCCCCEEEEETTEEEET
2149 T ss_pred EeCC---ceEEEEEccccc-cccccceE----Eecee---------eecc----CC------ccccccceeeeceeeEee
2150 Confidence 9988 345566676655 22211 11 12322 1211 23 3333334 4899999
2151
2152
2153 Q sp|P0DTC2|SPIK 673 SYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNL 752 (1273)
2154 Q Consensus 673 syqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnl 752 (1273)
2155 .+....-.|| .+...++ +.-....|.||+|||++|++|-+..+|.|.+|||.+|+||++.+|.+|
2156 T Consensus 558 ~g~~~~~~~~---~~~~~~~------------~~~~t~~v~IP~nft~~v~~Eyiq~~~~kv~idC~~YVC~~~~~C~~l 622 (1116)
2157 T 6IXB_B 558 DGSIIAVQPR---NVSYDSV------------SAIVTANLSIPSNWTTSVQVEYLQITSTPIVVDCSTYVCNGNVRCVEL 622 (1116)
2158 T ss_dssp TSCEECCCCC---BCCCCCC------------CCSCCEEEEEECCCCCCCEEEEEECCCCCEEECHCCCCCSSCHHHHHH
2159 T ss_pred CCCeeeecce---eccCCCC------------ccccceeEEccCCeeeeeEEEEeeccCCCeEEechhhccCCCHHHHHH
2160 Confidence 8876533332 2211111 111122599999999999999999999999999999999999999999
2161
2162
2163 Q sp|P0DTC2|SPIK 753 LLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSK----PSKRSFIEDLLFNKVTL 828 (1273)
2164 Q Consensus 753 llqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqilpdpsk----pskrsfiedllfnkvtl 828 (1273)
2165 |.|||+||..+++||.+.+..+|....+++...++-++.+.+..|++||||.+||.+.. ++.||+||||||+||..
2166 T Consensus 623 l~qYgs~C~~I~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~n~s~~l~~~~~~~~~~~~RS~iEDlLF~KV~t 702 (1116)
2167 T 6IXB_B 623 LKQYTSACKTIEDALRNSAMLESADVSEMLTFDKKAFTLANVSSFGDYNLSSVIPSLPRSGSRVAGRSAIEDILFSKLVT 702 (1116)
2168 T ss_dssp HHHTHHHHHHHHHHHHHHHHHHHHHHHHHCCBCHHHHHTTCGGGGGGGCCTTTSCCCCSSCCC----CHHHHHHHHTCCC
2169 T ss_pred HHHhhhHHHHHHHHHHHHHhhhcHHHHHHHhcCccccccccccccCCccccccccCCCCCCCccccccHHHHHHccceee
2170 Confidence 99999999999999999999999999999999999999999999999999999998753 35799999999999999
2171
2172
2173 Q sp|P0DTC2|SPIK 829 ADAGFIKQ-YGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFN 907 (1273)
2174 Q Consensus 829 adagfikq-ygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfn 907 (1273)
2175 +|.|++++ |.+|.+....|||+|||.+||+.||||.+++||++.||++|++|....|||. |..||||+||.+|+|
2176 T Consensus 703 ~glg~vd~dY~~C~~g~~i~DL~CaQ~ynGi~VLP~v~~~~~~a~YT~sl~g~m~~gg~t~----aaaiPFa~~vq~RlN 778 (1116)
2177 T 6IXB_B 703 SGLGTVDADYKKCTKGLSIADLACAQYYNGIMVLPGVADAERMAMYTGSLIGGIALGGLTS----AASIPFSLAIQSRLN 778 (1116)
2178 T ss_dssp ------CCCGGGTSSSSSCCCHHHHHHHTTEEECCCTTCHHHHHHHHHHHHHHHSCCSCSS----SSCCCGGGHHHHHHH
2179 T ss_pred cCCCcccHHHHHhcCCccHHHHhcccccCeEEEeCCCCCHHHHHHHHHHHHHHHHhhchhH----hhhChHHHHHHHHhh
2180 Confidence 99999988 9999999999999999999999999999999999999999999999999997 556899999999999
2181
2182
2183 Q sp|P0DTC2|SPIK 908 GIGVTQNVLYENQKLIANQFNSAIGKIQDS--------------LSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAI 973 (1273)
2184 Q Consensus 908 gigvtqnvlyenqklianqfnsaigkiqds--------------lsstasalgklqdvvnqnaqalntlvkqlssnfgai 973 (1273)
2185 |+|+||+||.||||+||+.||.|||.||+. ++++|+||.|+|||||++++||++|++||+.|||||
2186 T Consensus 779 ~~~l~~~vL~~NQ~~iA~sFN~A~~~i~~~f~~~n~ai~qts~~~~t~~~Al~kiQ~VVN~~~~aL~~l~~qL~~nFgAI 858 (1116)
2187 T 6IXB_B 779 YVALQTDVLQENQKILAASFNKAMTNIVDAFTGVNDAITQTSQALQTVATALNKIQDVVNQQGNSLNHLTSQLRQNFQAI 858 (1116)
2188 T ss_dssp HHSCCCCSCCHHHHHHHHHHHHHHHHHHHHHC---------CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCSSSS
2189 T ss_pred hhhhcHHHHHHHHHHHHHHHHHHHHHHHHHHHhhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
2190 Confidence 999999999999999999999999999987 455669999999999999999999999999999999
2191
2192
2193 Q sp|P0DTC2|SPIK 974 SSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFP 1053 (1273)
2194 Q Consensus 974 ssvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfp 1053 (1273)
2195 ||.++||.+|||++||++|+||||+|||.+|.+||+|+|.|++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+|
2196 T Consensus 859 Sssi~dIy~rLd~leAdaQvDRLItGRL~aLna~vtq~l~~~~~v~~sr~lA~qKinECVksQS~R~gFCGnG~Hv~S~~ 938 (1116)
2197 T 6IXB_B 859 SSSIQAIYDRLDIIQADQQVDRLITGRLAALNVFVSHTLTKYTEVRASRQLAQQKVNECVKSQSKRYGFCGNGTHIFSLV 938 (1116)
2198 T ss_dssp CSCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCTSCCSCTTTSSSSEEEEEEE
2199 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCcCcCCCCCCeeEEEee
2200 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
2201
2202
2203 Q sp|P0DTC2|SPIK 1054 QSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGV--FVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVI 1130 (1273)
2204 Q Consensus 1054 qsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregv--fvsngthwfvtqrnfyepqiittdntfvsgncdvvi 1130 (1273)
2205 |.||.|++|+|.+|+|.+-++.+++|.+|+++ ++..||++. |+.++.+|++|.|++|||..||..|...-..|||..
2206 T Consensus 939 q~AP~Gi~F~H~~~~P~~~~~v~a~~GlC~~~~~~~~~~~~~~~~~~~~~~~~~T~r~~y~Pr~~t~~d~v~~~~c~v~y 1018 (1116)
2207 T 6IXB_B 939 NAAPEGLVFLHTVLLPTQYKDVEAWSGLCVDGRNGYVLRQPNLALYKEGNYYRITSRIMFEPRIPTIADFVQIENCNVTF 1018 (1116)
2208 T ss_dssp EEETTEEEEEEEEECCSSEEEEEECSCCCCSSSCCCCCSSTTBCCBCSSSSCBCCBSSCCCCCCCCGGGCCCCCCCCTTS
2209 T ss_pred ecCCCeEEEEEEeeccceeEEEEEEEEEeecCCceEEecCCceEeEeeCCEEEEeccccccCCCCCccceEEeecCceeE
2210 Confidence 99999999999999999999999999999995 789999887 888888999999999999999999999999999999
2211
2212
2213 Q sp|P0DTC2|SPIK 1131 GIVNNTVYDPLQPELDSFKEELDKY-FKN--HTSPDVDLGDISGINASVVNIQKEIDR--------------LNEVAKNL 1193 (1273)
2214 Q Consensus 1131 givnntvydplqpeldsfkeeldky-fkn--htspdvdlgdisginasvvniqkeidr--------------lnevaknl 1193 (1273)
2215 .-++.++..+..|+.-.|++||+|+ +|+ |+-||.+ +..+|+.+.|+..||++ |+|+.|+|
2216 T Consensus 1019 ~~~~~~~~~~~~~~~~d~~~~~~~~~~~~~~~~~p~~~---~~~~n~t~lnl~~ei~~L~~~~~~l~~~~~~l~~~i~~l 1095 (1116)
2217 T 6IXB_B 1019 VNISRSELQTIVPEYIDVNKTLQELSYKLPNYTVPDLV---VEQYNQTILNLTSEISTLENKSAELNYTVQKLQTLIDNI 1095 (1116)
2218 T ss_dssp CCCCTTTHHHHSCCC-----------------------------------------------------------------
2219 T ss_pred EEcchhhcCCCCCCCCChHHHHHHHHhhCCCCCCCCCc---HHhccceeechHHHHHHHHHHHHHHHHHHHHHHHHHHHH
2220 Confidence 9999999999999999999999999 664 4556554 77899999999999999 99999999
2221
2222
2223 Q sp|P0DTC2|SPIK 1194 NESLIDLQELGKYEQYIKWPW 1214 (1273)
2224 Q Consensus 1194 neslidlqelgkyeqyikwpw 1214 (1273)
2225 |+++|||++|++||+||||||
2226 T Consensus 1096 N~s~idLe~L~~~e~YiKWPW 1116 (1116)
2227 T 6IXB_B 1096 NSTLVDLKWLNRVETYIKWPW 1116 (1116)
2228 T ss_dssp ---------------------
2229 T ss_pred HhcCccHHHhCeEEEEecCCC
2230 Confidence 999999999999999999999
2231
2232
2233 No 15
2234 >6CV0_A Spike protein; infectious bronchitis coronavirus, spike, pre-fusion; HET: NAG;{Infectious bronchitis virus}
2235 Probab=100.00 E-value=2.9e-125 Score=1068.92 Aligned_cols=651 Identities=31% Similarity=0.547 Sum_probs=514.4 Template_Neff=4.200
2236
2237 Q sp|P0DTC2|SPIK 524 VCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNK------KFLPFQQFGRDIADTTDAV--RDPQTLEILDITPCSFGGV 595 (1273)
2238 Q Consensus 524 vcgpkkstnlvknkcvnfnfngltgtgvltesnk------kflpfqqfgrdiadttdav--rdpqtleilditpcsfggv 595 (1273)
2239 +.|....++++.++||++|.-|.+|+|++++.+. -....+.+-.|.....|.. ++..++++..|+||....+
2240 T Consensus 399 v~g~~d~snI~ld~CvdYNIYG~tG~GvItnvt~s~~~~~yl~~~Gl~ildtSg~idlf~~Kn~~~g~~Y~V~PC~~V~~ 478 (1105)
2241 T 6CV0_A 399 VITRHNYNNITLNTCVDYNIYGRTGQGFITNVTDSAVSYNYLADAGLAILDTSGSIDIFVVQGEYGLTYYKVNPCEDVNQ 478 (1105)
2242 T ss_dssp SCCSCCSCCCCCSSCEEEEETTEEEEEEEEECTTTTTTTTCSCSSCCCEECGGGCEEEEEECSSSSCEEEEEEECTTSSE
2243 T ss_pred cccccccceeEeCeeeeEEecCceeeEEEEecCCccccceeeccCCeEEEeCCCCceEEEEEcCCCCcEEEEEeCccCce
2244 Confidence 6777888999999999999999999999999655 3334444444444445544 4478999999999999999
2245
2246
2247 Q sp|P0DTC2|SPIK 596 SVITPGTNTSNQVAVL-YQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNN--SYECDIPIGAGICA 672 (1273)
2248 Q Consensus 596 svitpgtntsnqvavl-yqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnn--syecdipigagica 672 (1273)
2249 +++..|. +-|++| +....|.++..-.. .+++-.|| +++...+. ..+|+++.|.++|.
2250 T Consensus 479 Q~VV~~~---~iVG~LTs~n~t~s~~~~n~~----------------~i~~~~g~-~~~~~s~~~~~~~c~~~~y~~~ci 538 (1105)
2251 T 6CV0_A 479 QFVVSGG---KLVGILTSRNETGSQLLENQF----------------YIKITNGT-RRFRRSITENVANCPYVSYGKFCI 538 (1105)
2252 T ss_dssp EEEEETT---EEEEEEESSCSSCSEECSSSE----------------ECCCCCSS-SCCCCCCCCCBSCCCSCBCSSEEE
2253 T ss_pred eEEEECC---EEEEEEEEeCCCcccceeceE----------------EEEeeCCc-ceeeecccCccccCcceeecceEE
2254 Confidence 9998887 788888 88888877543111 26777888 77665543 68899999999998
2255
2256
2257 Q sp|P0DTC2|SPIK 673 SYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNL 752 (1273)
2258 Q Consensus 673 syqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnl 752 (1273)
2259 -+... ++. +..+.+..|.+- +.-+...|.||+|||++|++|-+..+|.|.+|||.+|+||++.+|.+|
2260 T Consensus 539 ~~~g~----~~~--~~~~~l~~~~~p------~~~~~~~v~IP~nFtl~v~~EyiQt~~~kV~IDC~~YVC~~~~~C~~l 606 (1105)
2261 T 6CV0_A 539 KPDGS----IAT--IVPKQLEQFVAP------LLNVTENVLIPNSFNLTVTDEYIQTRMDKVQINCLQYVCGNSLDCRDL 606 (1105)
2262 T ss_dssp CSSSC----EEE--BCCCCCCCCCCC------CCCSSCCEEEESSCCCCEEEEEEECCCCEEEECHHHHHSCSCSSSHHH
2263 T ss_pred cCCCC----eee--eccceeeecccc------cceeeeEEEccCceeEeEEEEEEeecCCceEEEchhhccCCCHHHHHH
2264 Confidence 77651 111 111222223222 122566799999999999999999999999999999999999999999
2265
2266
2267 Q sp|P0DTC2|SPIK 753 LLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQI-YKTPPIKDF--GGFNFSQILPDPSKPSKRSFIEDLLFNKVTLA 829 (1273)
2268 Q Consensus 753 llqygsfctqlnraltgiaveqdkntqevfaqvkqi-yktppikdf--ggfnfsqilpdpskpskrsfiedllfnkvtla 829 (1273)
2269 |.|||+||..+++||.+.+..+|.+..+++...|.- +++|-+..| |+||||.+||.|++|++||+||||||+||..+
2270 T Consensus 607 l~qYgs~C~~I~~al~~~~~~e~~~~~~~~~~~~~~~~~~~~~~~~~~~~fN~s~ll~~~~~~~~RS~IEDLLF~KV~t~ 686 (1105)
2271 T 6CV0_A 607 FQQYGPVCDNILSVVNSIGQKEDMELLNFYSSTKPAGFNTPFLSNVSTGEFNISLLLTTPSSPRRRSFIEDLLFTSVESV 686 (1105)
2272 T ss_dssp HTTCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCSCCCCCCCSCSCCSSCCCTTTSCCSSCSSSCCSHHHHHHTTC---
2273 T ss_pred HHHHHHHHHHHHHHHHHHHhHHhHHHHHHHHhcCCCccccccccccCCCCcceeeecCCCCCcCcccHHHHHhcCceeec
2274 Confidence 999999999999999999999999999999999766 677777645 78999999999999999999999999999999
2275
2276
2277 Q sp|P0DTC2|SPIK 830 DAGFIKQYGDCLGDI--AARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFN 907 (1273)
2278 Q Consensus 830 dagfikqygdclgdi--aardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfn 907 (1273)
2279 |.|+-+.|..|.+.. .+|||+|||.+||+.||||++++||++.||++|++|....|||. |..|||||||.+|+|
2280 T Consensus 687 glg~d~~Y~~Ct~g~~~~i~DL~CAQyyNGimVLP~v~d~~~~amYTasL~g~m~~gg~ta----a~aiPFa~~vq~RlN 762 (1105)
2281 T 6CV0_A 687 GLPTDDAYKNCTAGPLGFLKDLACAREYNGLLVLPPIITAEMQTLYTSSLVASMAFGGITA----AGAIPFATQLQARIN 762 (1105)
2282 T ss_dssp ------CCCCTTSCCCCSSGGGHHHHHTTTEEEECCSSCTTSSTTHHHHHHHHHHHSSSCS----CSSCSSHHHHHHHHT
2283 T ss_pred CCCCcHHHHhccCCCCccHHHHhchhhcCcEEeeCCCCCHHHHHHHHHHHHHHHHhcchhH----hhhCcHHHHHHHHhc
2284 Confidence 999999999999996 79999999999999999999999999999999999999999994 667999999999999
2285
2286
2287 Q sp|P0DTC2|SPIK 908 GIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKV 987 (1273)
2288 Q Consensus 908 gigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkv 987 (1273)
2289 ++|+||+||.||||+||+.||.|||.||+.+.++++||.|+|||||++++||++|++||+.|||||||.++||.+|||++
2290 T Consensus 763 ~v~l~~~vL~~NQk~iA~sFN~A~~~i~~~f~~~~~Al~kiQ~VVN~q~~aL~~l~~qL~~nFgAISssi~dIy~rLd~l 842 (1105)
2291 T 6CV0_A 763 HLGITQSLLLKNQEKIAASFNKAIGRMQEGFRSTSLALQQIQHVVNKQNAILTETMASLNKNFGAISSLIQEIYQQLDAI 842 (1105)
2292 T ss_dssp TTTTCSCCCSSSSHHHHHHHHHHHHHHHHHTTSSCSHHHHHHHHHHHHHHHHTTTTTTSSSCCSSSCSCSTTTTTTSCHH
2293 T ss_pred hhhccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHH
2294 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
2295
2296
2297 Q sp|P0DTC2|SPIK 988 EAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTY 1067 (1273)
2298 Q Consensus 988 eaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvty 1067 (1273)
2299 ||++|+||||||||.+|++||+|.+.+.+|.||++.||..|+.|||..||+|.+|||.|.|++|+||.||+|++|+|.+|
2300 T Consensus 843 eAdaQvDRLItGRL~aLna~vt~~~~~~~~v~~sr~LA~qKiNECVksQS~R~gFCGnG~Hv~S~~q~AP~Gi~F~H~~~ 922 (1105)
2301 T 6CV0_A 843 QANAQVDRLITGRLSSLSVLASAKQAEHIRVSQQRELATQKINECVKSQSIRYSFCGNGRHVLTIPQNAPNGIVFIHFSY 922 (1105)
2302 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCTTCCCCTTSSSSSSCCCEEEEECSSEEEEEEECC
2303 T ss_pred HHHHHhHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhccCcccCCCCCCeEEEeeeeccCCeEEEEEEEe
2304 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
2305
2306
2307 Q sp|P0DTC2|SPIK 1068 VPAQEKNFTTAPAICHDG-----KAHFPR--EGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDP 1140 (1273)
2308 Q Consensus 1068 vpaqeknfttapaichdg-----kahfpr--egvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp 1140 (1273)
2309 +|.+-++.+++|.+|.++ .+..|+ .|+|+.+...|++|.|++|||..||.+|...-..|||...-+|+++..|
2310 T Consensus 923 ~P~~~~~v~a~~G~C~~~~~~~~~~~~~~~~~g~~~~~n~~~~~T~r~~y~Pr~~t~~d~v~i~sC~v~y~~~~~~~l~~ 1002 (1105)
2311 T 6CV0_A 923 TPDSFVNVTAIVGFCVKPANASQYAIVPANGRGIFIQVNGSYYITARDMYMPRAITAGDIVTLTSCQANYVSVNKTVITT 1002 (1105)
2312 T ss_dssp CCCCEEEECBCCCBCCCCSSSCCCEECCCTTSCCEEEETTEEEECCSSSCCCBCCCTTSCCEESCCCSSSCCCSSCCCCC
2313 T ss_pred ccCceeEEEEEEEEEecCcccccEEEEecCCCcEEEEECCEEEEeccccccCCCCCcccEEEeecCcceEEeCCcccccC
2314 Confidence 999999999999999997 588888 8999999899999999999999999999999999999999999999998
2315
2316
2317 Q sp|P0DTC2|SPIK 1141 -LQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELG-KYEQYIKW 1212 (1273)
2318 Q Consensus 1141 -lqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelg-kyeqyikw 1212 (1273)
2319 ..|+.-.|+|||+|+|+++++.-.|+. +-.+|.++.|++.||++|+|+.|+||+| +||+||. |.|.|..-
2320 T Consensus 1003 ~~~pd~~Dfn~el~~~~~~~~~~~p~~~-~~n~n~t~LnLt~Ei~~l~~~i~~lN~s-~dLe~L~~~~~~~~~~ 1074 (1105)
2321 T 6CV0_A 1003 FVDNDDFDFNDELSKWWNDTKHELPDFD-KFNYTVPILDIDSEIDRIQGVIQGLNDS-VDIKQIEDKIEEILSK 1074 (1105)
2322 T ss_dssp CC------------------------------------------------------------------------
2323 T ss_pred CCCcCCCChHHHHHHHHhcCCCCCCCcc-ccccccceechHHHHHHHHHHHHHHHhc-CCHHHHHHHHHHHHHH
2324 Confidence 579999999999999999976445563 3478889999999999999999999999 6999998 77877654
2325
2326
2327 No 16
2328 >6VV5_C Spike glycoprotein; glycoprotein, surface, receptor-binding, membrane fusion; HET: MAN, PAM, BMA, NAG;{Porcine epidemic diarrhea virus}
2329 Probab=100.00 E-value=1.7e-124 Score=1078.65 Aligned_cols=641 Identities=32% Similarity=0.536 Sum_probs=513.8 Template_Neff=4.600
2330
2331 Q sp|P0DTC2|SPIK 521 PATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITP 600 (1273)
2332 Q Consensus 521 patvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp 600 (1273)
2333 |..+.|-....+++.++||++|.-|.+|+|++++++..++..+. -.+.+.-.++.|+..++++..|+||....++|+..
2334 T Consensus 614 ~~pv~g~~d~s~i~l~~Cv~YnIYG~tG~GvI~~t~~~~~~g~~-y~s~~G~l~~Fk~~~~~~~Y~V~PC~~~~Q~vV~~ 692 (1356)
2335 T 6VV5_C 614 PKPFEGVTDVSFMTLDVCTKYTIYGFKGEGIITLTNSSFLAGVY-YTSDSGQLLAFKNVTSGAVYSVTPCSFSEQAAYVD 692 (1356)
2336 T ss_dssp SSCCSSCSCCCBCCCSSEEEEEETTEEEEEEEEECSCCCSSCSE-EECTTSCEEEEECTTTCCEEEEECSSCEEEEEEET
2337 T ss_pred cCCcccccccceeeeCeeeeeEeCCceeeEEEEEcCceecCceE-EEcCCCCEEEEEcCCCCCEEEEEecccCceEEEEC
2338 Confidence 44466777788999999999999999999999999988876666 57777788899999999999999999999999987
2339
2340
2341 Q sp|P0DTC2|SPIK 601 GTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPI----GAGICASYQT 676 (1273)
2342 Q Consensus 601 gtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsyecdipi----gagicasyqt 676 (1273)
2343 |+ -|+++-. .|++. -+-+++-.|| +.|.+...+|+.|+ |.|||+.+..
2344 T Consensus 693 g~----~Vg~lts-~n~~~--------------------~~~~~~~~~~---~~~~~~~~~c~~p~ltYg~~~ic~~g~~ 744 (1356)
2345 T 6VV5_C 693 DD----IVGVISS-LSSST--------------------FNSTRELPGF---FYHSNDGSNCTEPVLVYSNIGVCKSGSI 744 (1356)
2346 T ss_dssp TE----EEEEEES-CSCCS--------------------SSEEEEETTE---EEEESCCSCCSSEEEEETTEEEETTCCE
2347 T ss_pred CE----EEEEEEe-ecCCC--------------------CCceeecCce---eEecCCCccccceeEEeccceeecCCce
2348 Confidence 76 4555332 23321 1224555577 56667789999999 9999998776
2349
2350
2351 Q sp|P0DTC2|SPIK 677 QTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQY 756 (1273)
2352 Q Consensus 677 qtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqy 756 (1273)
2353 -...+ +.. .... +.-....|.||+|||++|++|-+..+|.|.+|||.+|+||++.+|.+||.||
2354 T Consensus 745 ~~~~~-~~~-------------~~~~--~~~~~~~v~IP~nft~~v~~Eyiq~~~~kv~idC~~YVC~~~~~C~~ll~qY 808 (1356)
2355 T 6VV5_C 745 GYVPS-QSG-------------QVKI--APTVTGNISIPTNFSMSIRTEYLQLYNTPVSVDCATYVCNGNSRCKQLLTQY 808 (1356)
2356 T ss_dssp EECCC-CCC-------------CCCC--CCCSSEEEEEEESCEEEEEEEEEECCCCCEEECHHHHHSSSCHHHHHHHGGG
2357 T ss_pred eeecC-ccC-------------CCCC--CcccceEEEecCCeEEEEEEEEEeecCCCeEEechhhccCCCHHHHHHHHHh
2358 Confidence 43222 110 0000 1122237899999999999999999999999999999999999999999999
2359
2360
2361 Q sp|P0DTC2|SPIK 757 GSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDF--GGFNFSQILPDPS-------KPSKRSFIEDLLFNKVT 827 (1273)
2362 Q Consensus 757 gsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdf--ggfnfsqilpdps-------kpskrsfiedllfnkvt 827 (1273)
2363 |+||..+++||.+.+..+|-.......-..+.++.+-+..| |+|||+.+||.+. ++++||+||||||+||.
2364 T Consensus 809 gs~C~~I~~al~~~~~~e~~e~~~~~~~~~~~~~~~~~s~~~~~~~n~s~~l~~~~~~~~~~~~~~~RS~IEDLLF~KV~ 888 (1356)
2365 T 6VV5_C 809 TAACKTIESALQLSARLESVEVNSMLTISDEALQLATISSFNGDGYNFTNVLGVSVYDPASGRVVQKRSFIEDLLFNKVV 888 (1356)
2366 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHTTCSTTTSCCSSCCCTTTSCEEC--------CEECCHHHHHHHHHHC
2367 T ss_pred HHHHHHHHHHHHHHHhhhcHHHHHhHhhCHHHHhhceeecccCCCcceeeecccccCCCCCCCccCCcCHHHHHhccceE
2368 Confidence 99999999999999999855444444444556666666666 7899999999874 33789999999999999
2369
2370
2371 Q sp|P0DTC2|SPIK 828 LADAGFI-KQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRF 906 (1273)
2372 Q Consensus 828 ladagfi-kqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrf 906 (1273)
2373 .+|.|++ +.|.+|.+...+|||+|||.+||+.||||++++||++.||++|++|....|||. |..||||+||.+|+
2374 T Consensus 889 t~glg~vD~~Y~~C~~g~~i~DL~CaQ~yNGi~VLP~v~~~~~~a~YT~sl~g~m~~gg~t~----aaaiPFa~~vq~Rl 964 (1356)
2375 T 6VV5_C 889 TNGLGTVDEDYKRCSNGRSVADLVCAQYYSGVMVLPGVVDAEKLHMYSASLIGGMVLGGFTS----AAALPFSYAVQARL 964 (1356)
2376 T ss_dssp -------CCCCTTTTSCSSCCCHHHHHHHTTEEECCCSSCHHHHHHHHHHHHHGGGCCSSSC----SSCCCHHHHHHHHH
2377 T ss_pred ecCCCCcchhHHHhcCCccHHHHhcccccCcEEEeCCCCCHHHHHHHHHHHHHHHHhcchhh----hhhChHHHHHHHHh
2378 Confidence 9999999 999999999999999999999999999999999999999999999999999997 44799999999999
2379
2380
2381 Q sp|P0DTC2|SPIK 907 NGIGVTQNVLYENQKLIANQFNSAIGKIQDSL--------------SSTASALGKLQDVVNQNAQALNTLVKQLSSNFGA 972 (1273)
2382 Q Consensus 907 ngigvtqnvlyenqklianqfnsaigkiqdsl--------------sstasalgklqdvvnqnaqalntlvkqlssnfga 972 (1273)
2383 |++|+||+||.||||+||+.||.|||.||+.+ +++++||.|+|||||++++||++|++||+.||||
2384 T Consensus 965 N~~~lt~~vL~~NQk~iA~sFN~A~~~i~~~f~~v~~ai~qts~~~~t~~~Al~kiQ~VVN~q~~aL~~l~~qL~~nFgA 1044 (1356)
2385 T 6VV5_C 965 NYLALQTDVLQRNQQLLAESFNSAIGNITSAFESVKEAISQTSKGLNTVAHALTKVQEVVNSQGAALTQLTVQLQHNFQA 1044 (1356)
2386 T ss_dssp HHHSCCCCCSSHHHHHHHHHHHHHHHHHHHHTTTGGGSCCTTTTSTTSHHHHHHHHHHHHHTTTTTHHHHHHGGGCCCSS
2387 T ss_pred hhhHhchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
2388 Confidence 99999999999999999999999999999886 8899999999999999999999999999999999
2389
2390
2391 Q sp|P0DTC2|SPIK 973 ISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCG-KGYHLMS 1051 (1273)
2392 Q Consensus 973 issvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcg-kgyhlms 1051 (1273)
2393 |||.++||.+|||++||++|+||||+|||.+|.+||+|+|.|++|+|+|+.||..|+.|||..||+|.+||| .|.|++|
2394 T Consensus 1045 ISssi~dIy~rLd~leAdaQvDRLItGRL~aLna~vsq~l~~~~~v~~sr~LA~qKinECVksQS~R~gFCGnnG~Hi~S 1124 (1356)
2395 T 6VV5_C 1045 ISSSIDDIYSRLDILSADAQVDRLITGRLSALNAFVAQTLTKYTEVQASRKLAQQKVNECVKSQSQRYGFCGGDGEHIFS 1124 (1356)
2396 T ss_dssp SCSCHHHHHTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCSSCCCSTTTSSSSSEEEEE
2397 T ss_pred HHHHHHHHHHHHHHHHHhhHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCccccCCCCCceEEEE
2398 Confidence 999999999999999999999999999999999999999999999999999999999999999999999999 7999999
2399
2400
2401 Q sp|P0DTC2|SPIK 1052 FPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVS--N----G--THWFVTQRNFYEPQIITTDNTFV 1122 (1273)
2402 Q Consensus 1052 fpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregvfvs--n----g--thwfvtqrnfyepqiittdntfv 1122 (1273)
2403 +||.||.|++|+|.+|+|.+-++.+++|.+|.++ ++..||++.|+- + + ..|++|.|++|||..||..+...
2404 T Consensus 1125 ~~q~APnGi~F~H~~~~P~~~~~v~a~~G~C~~~~~~~~~~~~~~~~~~~~~~n~~~~~~~~T~r~~y~Pr~~t~~d~v~ 1204 (1356)
2405 T 6VV5_C 1125 LVQAAPQGLLFLHTVLVPSDFVDVIAIAGLCVNDEIALTLREPGLVLFTHELQNHTATEYFVSSRRMFEPRKPTVSDFVQ 1204 (1356)
2406 T ss_dssp EEEEETTEEEEEEEEEECSEEEEEEECCCEEETTTEEEEESCTTEEEESCC-------CCEEEETTSCCCBCCCGGGEEE
2407 T ss_pred eccccCceEEEEEEeecccceeEEEEEEEEEeCCCceEEecCCceEEEeecccCCCCCeEEEeccccccCCCCCccceEE
2408 Confidence 9999999999999999999999999999999995 789999988766 3 1 58999999999999999999999
2409
2410
2411 Q sp|P0DTC2|SPIK 1123 SGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHT---SPDVDLGDISGINASVVNIQKEIDRL------------- 1186 (1273)
2412 Q Consensus 1123 sgncdvvigivnntvydplqpeldsfkeeldkyfknht---spdvdlgdisginasvvniqkeidrl------------- 1186 (1273)
2413 -..|||...-++.++..+..|++..|++||+|+||+++ -||.++ ..+|+.+.|++.||++|
2414 T Consensus 1205 ~~sC~v~y~n~~~~~~~~~~p~~~df~~el~~~~~~~~~~~~p~~~~---~~~n~t~Lnl~~ei~~l~~~~~~l~~~~~~ 1281 (1356)
2415 T 6VV5_C 1205 IESCVVTYVNLTRDQLPDVIPDYIDVNKTLDEILASLPNRTGPSLPL---DVFNATYLNLTGEIADLEQRSESLRNTTEE 1281 (1356)
2416 T ss_dssp ESCCCTTSEEECTTTGGGTSTTCCCHHHHHHC------------------------------------------------
2417 T ss_pred eecCeeEEEEcccccCCCCCCCCCChHHHHHHHHHcCCCCCCCCCCh---hcceeeeechHHHHHHHHHHHHHHhchHHH
2418 Confidence 99999999999999999999999999999999999884 455544 47999999999999997
2419
2420
2421 Q sp|P0DTC2|SPIK 1187 -NEVAKNLNESLIDLQELGKYEQYIKWP 1213 (1273)
2422 Q Consensus 1187 -nevaknlneslidlqelgkyeqyikwp 1213 (1273)
2423 +|+.|+||+++|||++|++||.+-+|+
2424 T Consensus 1282 l~~~i~~lN~s~idLe~Ln~~etla~~~ 1309 (1356)
2425 T 6VV5_C 1282 LQSLIYNINNTLVDLEWLNRVETGSGYI 1309 (1356)
2426 T ss_dssp ----------------------------
2427 T ss_pred HHHHHHHHHHhccCHHHHcceeecccCC
2428 Confidence 899999999999999999999987765
2429
2430
2431 No 17
2432 >6M3W_B Spike glycoprotein,Spike glycoprotein; spike, post-fusion, SARS-CoV, coronavirus, glycoprotein; HET: NAG;{Human SARS coronavirus}
2433 Probab=100.00 E-value=1.8e-124 Score=1000.40 Aligned_cols=491 Identities=90% Similarity=1.349 Sum_probs=338.6 Template_Neff=3.600
2434
2435 Q sp|P0DTC2|SPIK 706 AYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQV 785 (1273)
2436 Q Consensus 706 aysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqv 785 (1273)
2437 |++...|.||+|||++|++|-+.++|.|.+|||.+|+||++.+|.+||.|||+||..+++||.+.+..+|....+++...
2438 T Consensus 1 ~~~~~~i~IP~nFtl~v~~EyiQ~~~~kV~IDC~~YVC~~~~rC~~LL~QYgs~C~~I~~aL~~~~~led~~~~~~~s~~ 80 (491)
2439 T 6M3W_B 1 AYSNNTIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQYGSFCTQLNRALSGIAAEQDRNTREVFAQV 80 (491)
2440 T ss_dssp CCCCEEEEEEEEEEEEECCCEEECCCCCCCCCHHHHTCSSCHHHHHHHTTSTTHHHHHHHHHHHHC--------------
2441 T ss_pred CCCcceeeccCCeEEEEEEeeeeecCCceEEechhhccCCCHHHHHHHHHHHHHHHHHHHHHHHHHHhHhHHHHHHHHHH
2442 Confidence 34567799999999999999999999999999999999999999999999999999999999999999999999999999
2443
2444
2445 Q sp|P0DTC2|SPIK 786 KQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLL 865 (1273)
2446 Q Consensus 786 kqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlppll 865 (1273)
2447 ++-++.|-+..|+|||||.++|.++++++||+||||||+||..+|.|+.+.|..|.+....|||+|||.|||+.||||..
2448 T Consensus 81 ~~~~~~~~~~~~~~~N~s~~lp~~~~~~~RS~IEDLLF~KV~t~glG~~~dYk~Ct~g~~i~DL~CaQyyNGimVLP~v~ 160 (491)
2449 T 6M3W_B 81 KQMYKTPTLKYFGGFNFSQILPDPLKPTKRSFIEDLLFNKVTLADAGFMKQYGECLGDINARDLICAQKFNGLTVLPPLL 160 (491)
2450 T ss_dssp --------------------------------------------------------------------------------
2451 T ss_pred hHHhccCcccccCCccccccCCCCCCCCCcCHHHHHhcCceeecCCchhHhHHHccCCccHHHhhcccccCCEEeeCCCC
2452 Confidence 99999999999999999999999988999999999999999999999999999999999999999999999999999999
2453
2454
2455 Q sp|P0DTC2|SPIK 866 TDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASAL 945 (1273)
2456 Q Consensus 866 tdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasal 945 (1273)
2457 ++||++.||++|++|....|||+|+|+|..||||+||.||+||+|+||+||.||||+|||.||.|++.||+.++.+++||
2458 T Consensus 161 d~~~~a~YTasL~g~ma~gg~T~g~~saaaIPFa~~vq~RlN~valtt~VL~~NQk~iA~sFN~A~~~iq~g~~t~~~AL 240 (491)
2459 T 6M3W_B 161 TDDMIAAYTAALVSGTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTAL 240 (491)
2460 T ss_dssp -----------------------------------------------------CCHHHHHHHHHHHHHHHHHHHHHHHHH
2461 T ss_pred CHHHHHHHHHHHHHHHhccccccCcchhccchHHHHHHHHhccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
2462 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
2463
2464
2465 Q sp|P0DTC2|SPIK 946 GKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLA 1025 (1273)
2466 Q Consensus 946 gklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanla 1025 (1273)
2467 .|+|||||++++||++|++||+.|||||||.++||.+|||++||++|+||||+|||.+|.+||+|+|.|++|+|+|+.||
2468 T Consensus 241 ~KiQ~VVN~q~~aL~~L~~qL~nnFgAISssI~dIy~RLD~leAdaQVDRLItGRL~aLnafVtq~l~~~~ev~~sr~LA 320 (491)
2469 T 6M3W_B 241 GKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLA 320 (491)
2470 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
2471 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHH
2472 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
2473
2474
2475 Q sp|P0DTC2|SPIK 1026 ATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVT 1105 (1273)
2476 Q Consensus 1026 atkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvt 1105 (1273)
2477 ..|+.|||..||+|.+|||.|.|++|+||.||.|++|+|.+|+|.+-++.++.|.+|.++++..|++|+|+.|+..|++|
2478 T Consensus 321 ~qKiNECVKSQS~R~gFCGnGtHi~Si~q~APnGi~F~H~~~~Pt~~~~V~a~~GlC~~~~~~~~~~g~f~~~~~~~~iT 400 (491)
2479 T 6M3W_B 321 ATKMSECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPAICHEGKAYFPREGVFVFNGTSWFIT 400 (491)
2480 T ss_dssp HHHCCCCCSSCCCCBTSSSSSEEEEEEEEECSSEEEEEEEEEEEEEEEEEEEBSCCCSSSCCCEETTCCEECSSSCCEEC
2481 T ss_pred HHHHHHHHhccCcCcCcCCCCeeEEeccccCCCeEEEEEEEeCccceeEEEEeceEeecCceEeeeceeEEEcCcEEEEe
2482 Confidence 99999999999999999999999999999999999999999999999999999999999998999999999899999999
2483
2484
2485 Q sp|P0DTC2|SPIK 1106 QRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDR 1185 (1273)
2486 Q Consensus 1106 qrnfyepqiittdntfvsgncdvvigivnntvydplqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidr 1185 (1273)
2487 .|++|||..||..|...-..|||...-+|+++.+|++|++..|+|||++|+||+|+|+.++++++.+|+++.|++.||++
2488 T Consensus 401 ~r~my~Pr~~t~~d~V~itsC~V~y~Nvn~~~~~~~~Pdy~df~del~~~~~N~T~p~~~l~~ld~fN~T~LNLt~EI~~ 480 (491)
2489 T 6M3W_B 401 QRNFFSPQIITTDNTFVSGNCDVVIGIINNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDR 480 (491)
2490 T ss_dssp CSSSCCCEECCSSSEECCSSCCCBCCCCCCSCCCCCCCCCCCHHHHHHHSCCCCCCCCCCCSHHHHCCCCCCCCCHHHHH
2491 T ss_pred ccccccCccCCCCceEEeecceeEEEEecccccCCCCCCCCCHHHHHHHHccCCCCCCCCCCCcccccccccchHHHHHH
2492 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
2493
2494
2495 Q sp|P0DTC2|SPIK 1186 LNEVAKNLNES 1196 (1273)
2496 Q Consensus 1186 lnevaknlnes 1196 (1273)
2497 |++++++||+|
2498 T Consensus 481 Lq~~i~~Ln~s 491 (491)
2499 T 6M3W_B 481 LNEVAKNLNES 491 (491)
2500 T ss_dssp HHHHHHHHHHC
2501 T ss_pred HHHHHHHHHcC
2502 Confidence 99999999986
2503
2504
2505 No 18
2506 >6U7K_C Spike glycoprotein; PEDV, Spike, Coronavirus, Fusion Protein; HET: MAN, BMA, NAG; 3.14A {Porcine epidemic diarrhea virus (strain CV777)}
2507 Probab=100.00 E-value=1.1e-122 Score=1065.47 Aligned_cols=641 Identities=33% Similarity=0.542 Sum_probs=505.8 Template_Neff=4.600
2508
2509 Q sp|P0DTC2|SPIK 521 PATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITP 600 (1273)
2510 Q Consensus 521 patvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp 600 (1273)
2511 |..+.|-....|++.++||++|..|.+|+|++++++..+...+ +..+.+...++.|+..++++..|+||..+.+.|+..
2512 T Consensus 629 ~~pv~g~~d~sni~l~~CvdYnIYG~tG~GvI~~t~~~~~~g~-~y~s~~G~l~~Fk~~~~~~~Y~V~PC~~~~Q~vv~~ 707 (1399)
2513 T 6U7K_C 629 PKPLEGITDVSFMTLDVCTKYTIYGFKGEGIITLTNSSILAGV-YYTSDSGQLLAFKNVTSGAVYSVTPCSFSEQAAYVN 707 (1399)
2514 T ss_dssp SSCCCCSSCCCBCCCSSEEEEEETTEEEEEEEEEESCCCSSCS-EEECSSSSEEEEECTTTCCEEEEECSSCEEEEEEET
2515 T ss_pred cCCCccccccceeeeCeeEeeEeCCceeeEEEEEcCceeeCce-EEEcCCCCEEEEECCCCCCEEEEEeceeccEEEEEC
2516 Confidence 4446777888999999999999999999999999998887777 889999999999999999999999999887744443
2517
2518
2519 Q sp|P0DTC2|SPIK 601 GTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPI----GAGICASYQT 676 (1273)
2520 Q Consensus 601 gtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsyecdipi----gagicasyqt 676 (1273)
2521 |+ -|.++ ...|++. ..| +++-.|| +.|.+...+|+.|+ |.|||+.+..
2522 T Consensus 708 ~~----~vg~l-ts~n~~~-------------------~~~-~~~~~~~---~~~s~~~~~c~~p~ltYg~~~ic~~g~~ 759 (1399)
2523 T 6U7K_C 708 DD----IVGVI-SSLSNST-------------------FNN-TRELPGF---FYHSNDGSNCTEPVLVYSNIGVCKSGSI 759 (1399)
2524 T ss_dssp TE----EEEEE-ESCSCCS-------------------SSE-EEECSSC---EEEESCCSCCSCEEEEETTEEEETTSCE
2525 T ss_pred CE----EEEEe-EeeeCCC-------------------CCC-eeecCce---eEecCCCcccccceEEecCceeeecCcc
2526 Confidence 22 23322 2223321 223 6778888 77888899999999 9999998876
2527
2528
2529 Q sp|P0DTC2|SPIK 677 QTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQY 756 (1273)
2530 Q Consensus 677 qtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqy 756 (1273)
2531 -.-+|+ .+.. .|. . -....|.||+|||++|++|-+.++|.|.+|||.+|+||++.+|.++|.||
2532 T Consensus 760 ~~~~~~-~~~~------~~~--~-------~~~~~v~IP~nft~~v~~Eyiq~~~~kV~VdCnvYVC~~N~rC~~lL~QY 823 (1399)
2533 T 6U7K_C 760 GYVPSQ-YGQV------KIA--P-------TVTGNISIPTNFSMSIRTEYLQLYNTPVSVDCATYVCNGNSRCKQLLTQY 823 (1399)
2534 T ss_dssp EECCCC-BCCC------CCC--C-------CSSSEEEEECSEEEEEEEEEEECCCCCEEECHHHHHHTTCHHHHHHHTTS
2535 T ss_pred ccccCc-cccc------ccc--c-------ccceeEEecCCeEEEEEEEEEeecCCCeEEEceEEEeCCCHHHHHHHHHH
2536 Confidence 433331 1111 110 0 11227899999999999999999999999999999999999999999999
2537
2538
2539 Q sp|P0DTC2|SPIK 757 GSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDF--GGFNFSQILPDPS----K---PSKRSFIEDLLFNKVT 827 (1273)
2540 Q Consensus 757 gsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdf--ggfnfsqilpdps----k---pskrsfiedllfnkvt 827 (1273)
2541 |+||..+|.||.+.+-.++-...+....-.+.++++-+..| ++|||+.++|.+. + ++.||+||||||+||.
2542 T Consensus 824 gs~C~nIn~aL~~s~~le~~E~~~~~t~si~~l~~~~~s~~~~~d~N~s~ll~~~~~~p~~d~~~~~RSvIEDLLF~KV~ 903 (1399)
2543 T 6U7K_C 824 TAACKTIESALQLSARLESVEVNSMLTISEEALQLATISSFNGDGYNFTNVLGASVYDPASGRVVQKRSVIEDLLFNKVV 903 (1399)
2544 T ss_dssp TTHHHHHHHHHHHHHHHHHHHHHHHCCBCHHHHHHHTTSCCCCTTCCCHHHHCC------------CCCHHHHHHHHTTT
2545 T ss_pred HHHHHHHHHHHHHHHhhhhHHHHhhhccCHHHHhhhceeccCCCcceeeeeeccccCCCCCCCcCCcccHHHHHheeceE
2546 Confidence 99999999999998877644333334444555555555444 7899999887542 2 4789999999999999
2547
2548
2549 Q sp|P0DTC2|SPIK 828 LADAGFI-KQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRF 906 (1273)
2550 Q Consensus 828 ladagfi-kqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrf 906 (1273)
2551 .+|.|++ +.|..|.+...+|||+|||.+||+.||||++++||++.||++|++|....|||. |..||||+||.+|+
2552 T Consensus 904 t~glg~vD~~Y~~C~~g~~i~DL~CaQ~yNGi~VLP~v~~~~~~a~YT~sl~g~m~~gg~ta----aaaiPFa~~vq~Rl 979 (1399)
2553 T 6U7K_C 904 TNGLGTVDEDYKRCSNGRSVADLVCAQYYSGVMVLPGVVDAEKLHMYSASLIGGMALGGITA----AAALPFSYAVQARL 979 (1399)
2554 T ss_dssp TTCCSSSCCCGGGGSSCSSCCCHHHHHHHTTEEECCCSSCHHHHHHHHHHHHGGGGCCCSSC----SSCCCHHHHHHHHH
2555 T ss_pred ecCCCCcchhhHHhcCCccHHHHhcccccCcEEEeCCCCCHHHHHhHHHHHHHHHHhcchhH----hhhChHHHHHHHHh
2556 Confidence 9999999 999999999999999999999999999999999999999999999999999997 66799999999999
2557
2558
2559 Q sp|P0DTC2|SPIK 907 NGIGVTQNVLYENQKLIANQFNSAIGKIQDSLS--------------STASALGKLQDVVNQNAQALNTLVKQLSSNFGA 972 (1273)
2560 Q Consensus 907 ngigvtqnvlyenqklianqfnsaigkiqdsls--------------stasalgklqdvvnqnaqalntlvkqlssnfga 972 (1273)
2561 |++|+||+||.||||+||+.||.||+.||+.++ ++++||.|+|||||++++||++|++||+.||||
2562 T Consensus 980 N~~~lt~~vL~~NQk~iA~sFN~A~~~iq~~f~~v~~ai~qts~~~~t~~~Al~kiQ~VVN~~~~aL~~l~~qL~~nFgA 1059 (1399)
2563 T 6U7K_C 980 NYLALQTDVLQRNQQLLAESFNSAIGNITSAFESVKEAISQTSKGLNTVAHALTKVQEVVNSQGSALNQLTVQLQHNFQA 1059 (1399)
2564 T ss_dssp HTTSCCCCCSSTHHHHHHHHHHHHHHHHHTTTTCCGGGCCGGGGSTTSHHHHHHHHHHHHHHTTHHHHHHHHTTSCCTTS
2565 T ss_pred hhhHHchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
2566 Confidence 999999999999999999999999999999866 899999999999999999999999999999999
2567
2568
2569 Q sp|P0DTC2|SPIK 973 ISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCG-KGYHLMS 1051 (1273)
2570 Q Consensus 973 issvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcg-kgyhlms 1051 (1273)
2571 |||.++||++|||++||++|+||||+|||.+|.+||+|+|+|++|+|+|+.||..|+.|||..||+|.+||| .|.|++|
2572 T Consensus 1060 ISssi~dIy~rLd~leAdaQvDRLItGRL~aLna~vtq~l~~~~~v~~sr~LA~qKinECVksQS~R~gFCGnnG~Hv~S 1139 (1399)
2573 T 6U7K_C 1060 ISSSIDDIYSRLDILSADVQVDRLITGRLSALNAFVAQTLTKYTEVQASRKLAQQKVNECVKSQSQRYGFCGGDGEHIFS 1139 (1399)
2574 T ss_dssp SCSCHHHHHTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCSSCCCSTTTTTSSSEEEEE
2575 T ss_pred HHHHHHHHHHHHHHHHHhhHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCccccCCCCCceEEEE
2576 Confidence 999999999999999999999999999999999999999999999999999999999999999999999999 7999999
2577
2578
2579 Q sp|P0DTC2|SPIK 1052 FPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVSNG--------THWFVTQRNFYEPQIITTDNTFV 1122 (1273)
2580 Q Consensus 1052 fpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregvfvsng--------thwfvtqrnfyepqiittdntfv 1122 (1273)
2581 +||.||.|++|+|.+|+|.+-++.+++|.+|+++ ++..||++.|+-.. ..|++|.|++|||..||.++...
2582 T Consensus 1140 ~~q~APnGi~F~H~~~~P~~~~~v~a~~G~C~~~~~~~~~~~~~~v~~~~~~~~~~~~~~~~T~r~~y~Pr~~t~~d~v~ 1219 (1399)
2583 T 6U7K_C 1140 LVQAAPQGLLFLHTVLVPGDFVNVLAIAGLCVNGEIALTLREPGLVLFTHELQTYTATEYFVSSRRMFEPRKPTVSDFVQ 1219 (1399)
2584 T ss_dssp EEEEETTEEEEEEEEEEESCEEEEEECCCEEETTTEEEEESCTTEEEEESCTTSSSCSCCEEEESSSCCCBCCCTTTEEE
2585 T ss_pred eccccCceEEEEEEEeccCceEEEEEEEEEEecCCeeEEecCCceEEEeeCCcccccceEEEeccccccCCCCCccceEE
2586 Confidence 9999999999999999999999999999999995 78999999766532 48999999999999999999999
2587
2588
2589 Q sp|P0DTC2|SPIK 1123 SGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHT---SPDVDLGDISGINASVVNIQKEIDRLNE----------- 1188 (1273)
2590 Q Consensus 1123 sgncdvvigivnntvydplqpeldsfkeeldkyfknht---spdvdlgdisginasvvniqkeidrlne----------- 1188 (1273)
2591 -..|||...-++.++..+..|++-.|++||+|+||+++ .||.++ ..+|+.+.|++.||++|++
2592 T Consensus 1220 ~~~c~v~y~~~~~~~~~~~~p~~~d~~~~l~~~~~~~~~~~~p~~~~---~~~n~t~lnl~~ei~~l~~~~~~l~~~~~~ 1296 (1399)
2593 T 6U7K_C 1220 IESCVVTYVNLTSDQLPDVIPDYIDVNKTLDEILASLPNRTGPSLPL---DVFNATYLNLTGEIADLEQRSESLRNTTEE 1296 (1399)
2594 T ss_dssp ESSCCTTSEEECTTTHHHHSTTC---------------------------------------------------------
2595 T ss_pred eecCeeEEEEcCcccCCCCCCCCCChHHHHHHHHHcCCCCCCCCCCh---hcceeeeechHHHHHHHHHHHHHHHhHHHH
2596 Confidence 99999999999999999999999999999999999884 455543 4789999999999999877
2597
2598
2599 Q sp|P0DTC2|SPIK 1189 ---VAKNLNESLIDLQELGKYEQYIKWP 1213 (1273)
2600 Q Consensus 1189 ---vaknlneslidlqelgkyeqyikwp 1213 (1273)
2601 +.|+||+++|||++|++||.|+||-
2602 T Consensus 1297 ~~~~i~~lN~s~idLe~L~~~et~~~~~ 1324 (1399)
2603 T 6U7K_C 1297 LRSLINNINNTLVDLEWLNRVETGSGYI 1324 (1399)
2604 T ss_dssp ----------------------------
2605 T ss_pred HHHHHHHHHHhccCHHHHcceeecCccC
2606 Confidence 9999999999999999999999993
2607
2608
2609 No 19
2610 >6BFU_C Spike protein; coronavirus spike glycoprotein, porcine deltacoronavirus; HET: MAN, BMA, NAG; 3.5A {Porcine deltacoronavirus}
2611 Probab=100.00 E-value=3.5e-119 Score=1017.49 Aligned_cols=746 Identities=30% Similarity=0.489 Sum_probs=605.1 Template_Neff=4.700
2612
2613 Q sp|P0DTC2|SPIK 267 VGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQ-PTESIVRFPNITNLCPFGEVFNAT 345 (1273)
2614 Q Consensus 267 vgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvq-ptesivrfpnitnlcpfgevfnat 345 (1273)
2615 +.|...-..|+ |-.||+|.|.+.|--.|+..-||.-.+|....|.|..++..+. ..+.+|..|+..+....- .|.+
2616 T Consensus 240 va~a~~tdVL~-~f~ngtIq~viyCD~sp~~~LaCqy~tfnfsDGFYp~t~~~~v~~~ktfV~lP~~~nhT~v~--ln~t 316 (1024)
2617 T 6BFU_C 240 FALANLTDTLI-TLTNTTISQITYCDKSVVDSIACQRSSHEVEDGFYSDPKSAVRARQRTIVTLPKLPELEVVQ--LNIS 316 (1024)
2618 T ss_dssp EEEEEEEEEEE-EEETTEEEEEEETTTCHHHHHHHHTTSSSCCSEEEECGGGCBCCSEEEEECSCCCCCEEEEE--EEEE
2619 T ss_pred EEEeeccchhe-eeeCCcccEEEECCCChhcccchhccccccCCCccCCCccccccCCceEEEcCCCCceeEEE--EEEE
2620 Confidence 34444444555 8899999999999977999999999999999999999988764 556899999987765421 1111
2621
2622
2623 Q sp|P0DTC2|SPIK 346 RFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKL 425 (1273)
2624 Q Consensus 346 rfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynykl 425 (1273)
2625 -+...-+ ... +++..|+ -+..|..+ ++ +.+
2626 T Consensus 317 f~n~s~a---g~v----------------~~i~~~~-----~s~yCV~n----s~----------------------ft~ 346 (1024)
2627 T 6BFU_C 317 AHMDFGE---ARL----------------DSVTING-----NTSYCVTK----PY----------------------FRL 346 (1024)
2628 T ss_dssp EEEETTE---EEE----------------EEEEETT-----BSEEECCS----SE----------------------EEE
2629 T ss_pred EeecCCC---Ccc----------------eeEEEec-----cceeEecC----Ce----------------------EEE
2630 Confidence 1110000 000 0011111 11122211 00 111
2631
2632
2633 Q sp|P0DTC2|SPIK 426 PDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERD----------ISTEIYQAGSTPCNGVEGFNCYFPLQSY 495 (1273)
2634 Q Consensus 426 pddftgcviawnsnnldskvggnynylyrlfrksnlkpferd----------isteiyqagstpcngvegfncyfplqsy 495 (1273)
2635 ..+|.. |+.|.+ .+ ..--||..+ ++-.+.+.| |-++....
2636 T Consensus 347 ~~~f~~--------------g~sy~~----~~-~~sCpFr~e~INNyL~FnSlCvSl~~gg-----------Ck~~v~~~ 396 (1024)
2637 T 6BFU_C 347 ETNFMC--------------TGCTMN----LR-TDTCSFDLSAVNNGMSFSQFCLSTESGA-----------CEMKIIVT 396 (1024)
2638 T ss_dssp EEECCE--------------ESSEEE----EE-ESSSSSCHHHHTTTCEEEEEEEESSCCS-----------EEEEEEEE
2639 T ss_pred EEEEee--------------ccCccc----cc-CCCCCCChhhccCCCccCeEEEEeCCCc-----------eeeEEEEE
2640 Confidence 111110 001111 00 011122211 111111222 54444432
2641
2642
2643 Q sp|P0DTC2|SPIK 496 GFQPTNGVGYQPYRVVVLSFE---LLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADT 572 (1273)
2644 Q Consensus 496 gfqptngvgyqpyrvvvlsfe---llhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadt 572 (1273)
2645 . ...|++++.|.++++ ......++|. +..++++.++||++|.-|.+|+|+++++|..+...+.+ .|...-
2646 T Consensus 397 ~-----~~sy~~~~~VyVt~s~Gsri~g~~~~~~-~d~s~i~l~~CvdYnIYG~tG~GvI~~~n~~~~~Gl~~-~s~sG~ 469 (1024)
2647 T 6BFU_C 397 Y-----VWNYLLRQRLYVTAVEGQTHTGTTSVHA-TDTSSVITDVCTDYTIYGVSGTGIIKPSDLLLHNGIAF-TSPTGE 469 (1024)
2648 T ss_dssp S-----SSEEECSCCEEEEEEEEEEEEECSSSSC-CCTTCCCCSSEEEEEETTEEEEEEEEECSCCCCSCSEE-ECTTSC
2649 T ss_pred E-----EeeeeceeEEEEEecCCCeeeccCCccC-CCCCceeeceeeeEEecCeeeeEEEecCCEEeeCcEEE-EcCCCC
2650 Confidence 1 123678888888877 3334445664 56699999999999999999999999999999989988 899999
2651
2652
2653 Q sp|P0DTC2|SPIK 573 TDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIG 652 (1273)
2654 Q Consensus 573 tdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragclig 652 (1273)
2655 .++.+++.++++..|+||....++|+..|.- |+ ++...| +++++.|++..||..+
2656 T Consensus 470 L~~Fk~~~~g~~Y~V~PC~~v~Q~vV~~g~i----VG-~lts~n--------------------~t~s~~f~~~~~~~~~ 524 (1024)
2657 T 6BFU_C 470 LYAFKNITTGKTLQVLPCETPSQLIVINNTV----VG-AITSSN--------------------STENNRFTTTIVTPTF 524 (1024)
2658 T ss_dssp EEEEEETTTTEEEEEECSSCCEEEEEETTEE----EE-EEESCG--------------------GGCCTTCSEEEEETTE
2659 T ss_pred eeEEEeCCCCCEEEEeeCCCCcEEEEECCEE----EE-EEEccC--------------------CCCCccccceeEecee
2660 Confidence 9999999999999999999877765544433 22 122222 3478889999999999
2661
2662
2663 Q sp|P0DTC2|SPIK 653 AEHVNN-SYECDIPIGA----GICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEIL 727 (1273)
2664 Q Consensus 653 aehvnn-syecdipiga----gicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteil 727 (1273)
2665 +.+.++ ..+|+.|+|. |||+.+..-...|+.. + ..-.+...++.|.||+|||++|++|-+
2666 T Consensus 525 ~~~s~~~~~~C~~p~~syg~~giC~dg~~~~~~~~~~----------~-----~p~~~~~vt~~i~IP~nft~~v~~Eyi 589 (1024)
2667 T 6BFU_C 525 FYSTNATTFNCTKPVLSYGPISVCSDGAIVGTSTLQN----------T-----RPSIVSLYDGEVEIPSAFSLSVQTEYL 589 (1024)
2668 T ss_dssp EEEECCSCCCCSCEEEEETTEEEETTSCEEECCCEEC----------C-----CSCSSCCCCSSEEEEEEEEEEEEEEEE
2669 T ss_pred eeecCCCccccccceeeccceeEccCCccccceeeec----------c-----CCceeeccCeEEEccCceEeeEEEeEE
2670 Confidence 999875 7999999999 9999886633322110 0 111123344589999999999999999
2671
2672
2673 Q sp|P0DTC2|SPIK 728 PVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFG-GFNFSQIL 806 (1273)
2674 Q Consensus 728 pvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfg-gfnfsqil 806 (1273)
2675 ..+|.|.+|||.+|+||++.+|.+||.|||+||..+++||.+.+..+|.+..+++...++-++.+-|..|+ +||||.+|
2676 T Consensus 590 q~~~~kv~idC~~YVC~~~~~C~~ll~qYg~~C~~I~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~n~s~~l 669 (1024)
2677 T 6BFU_C 590 QVQAEQVIVDCPQYVCNGNSRCLQLLAQYTSACSNIEAALHSSAQLDSREIINMFQTSTQSLQLANITNFKGDYNFSSIL 669 (1024)
2678 T ss_dssp ECCCCEEEECHHHHHHTTBHHHHHHHTTSTTHHHHHHHHHHHHHHHHHHHHHHHTCEEHHHHHHTCGGGGCSSSCCTTTS
2679 T ss_pred eeecCceEEecchhhcCCCHHHHHHHHHhhhHHHHHHHHHHHHHhhhhHHHHHHHhhCcccccccccccCCCCccchhhc
2680 Confidence 99999999999999999999999999999999999999999999999999999999999999998888884 69999999
2681
2682
2683 Q sp|P0DTC2|SPIK 807 PDPSKPSKRSFIEDLLFNKVTLADAGFI-KQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSG 885 (1273)
2684 Q Consensus 807 pdpskpskrsfiedllfnkvtladagfi-kqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsg 885 (1273)
2685 |.+. +.||+||||||+||..+|.|++ +.|.+|.+....|||+|||.+||+.||||.+++||++.||++|++|....|
2686 T Consensus 670 ~~~~--~~RS~iEDlLF~KV~t~glg~vD~~Y~~C~~g~~i~DL~CaQ~ynGi~VLP~v~~~~~~a~YT~sl~g~m~~gg 747 (1024)
2687 T 6BFU_C 670 TTRI--GGRSAIEDLLFNKVVTSGLGTVDQDYKSCSRDMAIADLVCSQYYNGIMVLPGVVDAEKMAMYTGSLTGAMVFGG 747 (1024)
2688 T ss_dssp CSST--TCCCHHHHHCCCCCCC------CCCGGGGGSTTGGGSHHHHHHTTTEEEECCSSCHHHHHHHHHHHHHGGGCCS
2689 T ss_pred CCCC--CCccHHHHHHcceeeecCCCccchHHHhccCCccHHHHhhccccCeEEEeCCCCCHHHHHHHHHHHHHHHHhhc
2690 Confidence 8774 7999999999999999999999 899999999999999999999999999999999999999999999999999
2691
2692
2693 Q sp|P0DTC2|SPIK 886 WTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSS--------------TASALGKLQDV 951 (1273)
2694 Q Consensus 886 wtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslss--------------tasalgklqdv 951 (1273)
2695 ||. |..||||+||.+|+|++|+||+||.||||+|||.||.|||.||+.+++ +++||.|+|||
2696 T Consensus 748 ~ta----aaaiPFa~~vq~RlN~~~lt~~vL~~NQ~~iA~sFN~A~~~i~~~f~~v~~ai~qts~~~~t~~~Al~kiQ~V 823 (1024)
2697 T 6BFU_C 748 LTA----AAAIPFATAVQARLNYVALQTNVLQENQKILAESFNQAVGNISLALSSVNDAIQQTSEALNTVAIAIKKIQTV 823 (1024)
2698 T ss_dssp SSS----SCCCCHHHHHHHHHHHHTTSSSCCSTTHHHHHHHHHHHHHHHHHHHHTTCCSCCTTCHHHHHHHHHHHHHHHH
2699 T ss_pred HHH----hHhChHHHHHHHHhhhhhhchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
2700 Confidence 997 556899999999999999999999999999999999999999988555 99999999999
2701
2702
2703 Q sp|P0DTC2|SPIK 952 VNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSE 1031 (1273)
2704 Q Consensus 952 vnqnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmse 1031 (1273)
2705 ||++++||++|++||+.|||||||.++||.+|||++||++|+||||+|||.+|.+||+|+|.|++|+|+|+.||..|+.|
2706 T Consensus 824 VN~~~~aL~~l~~qL~~nFgAISssi~dIy~rLd~leAdaQvDRLItGRL~aLna~vtq~l~~~~~v~~sr~lA~qKinE 903 (1024)
2707 T 6BFU_C 824 VNQQGEALSHLTAQLSNNFQAISTSIQDIYNRLEEVEANQQVDRLITGRLAALNAYVTQLLNQMSQIRQSRLLAQQKINE 903 (1024)
2708 T ss_dssp HHTTTHHHHHHHHGGGCCCSSSCSCHHHHHHHSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
2709 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
2710 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
2711
2712
2713 Q sp|P0DTC2|SPIK 1032 CVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVF-VSNGTHWFVTQRNF 1109 (1273)
2714 Q Consensus 1032 cvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregvf-vsngthwfvtqrnf 1109 (1273)
2715 ||..||+|.+|||.|.|++|+||.||.|++|+|.+|+|.+-++.+++|.+|+++ ++..|+.|.+ +.+...|++|.|++
2716 T Consensus 904 CVksQS~R~gFCGnG~Hv~S~~q~AP~Gi~F~H~~~~P~~~~~v~a~~G~C~~~~~~~~~~~g~~~~~~n~~~~~T~r~~ 983 (1024)
2717 T 6BFU_C 904 CVKSQSPRYGFCGNGTHIFSLTQTAPNGIFFMHAVLVPNKFTRVNASAGICVDNTRGYSLQPQLILYQFNNSWRVTPRNM 983 (1024)
2718 T ss_dssp CCCSCCCCTTTSSSSEEEEEEEEEETTEEEEEEEEEEEEEEEEECCBCEEEETTTEEEEECTTEEEEEETTEEEEEESSS
2719 T ss_pred HHhccCCCcCCCCCCeeEEEeeecCCCeEEEEEEEecccceeEEEEEEEEeecCCceEEeCCceEEEeeCCEEEEecccc
2720 Confidence 999999999999999999999999999999999999999999999999999995 7888888866 78778999999999
2721
2722
2723 Q sp|P0DTC2|SPIK 1110 YEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSF 1148 (1273)
2724 Q Consensus 1110 yepqiittdntfvsgncdvvigivnntvydplqpeldsf 1148 (1273)
2725 |||..||..|...-..|||...-+|+++..+..|++-.|
2726 T Consensus 984 y~Pr~~t~~d~v~~~sC~v~y~n~~~~~~~~~~p~~~D~ 1022 (1024)
2727 T 6BFU_C 984 YEPRLPRQADFIQLTDCSVTFYNTTAANLPNIIPDIIDV 1022 (1024)
2728 T ss_dssp CCCBCCCGGGEEEESSCCTTSEEECTTTGGGTSTTCCCT
2729 T ss_pred ccCCCCCcccEEEcccceeEEEECCcccCCCCCCCCCCC
2730 Confidence 999999999999999999999999999999988886544
2731
2732
2733 No 20
2734 >6B3O_B Spike glycoprotein; Coronavirus, membrane fusion, MHV, SARS; 4.1A {Murine coronavirus}
2735 Probab=100.00 E-value=7.3e-117 Score=954.95 Aligned_cols=497 Identities=42% Similarity=0.726 Sum_probs=333.3 Template_Neff=3.300
2736
2737 Q sp|P0DTC2|SPIK 703 NSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVF 782 (1273)
2738 Q Consensus 703 nsvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevf 782 (1273)
2739 .....++..|.||+|||++|++|-+.++|.|.+|||.+|+||++.+|.+||.|||+||..+++||.|.+..+|....+++
2740 T Consensus 45 ~~~~~~~~~isIP~nFtlsv~~EyiQt~~~kVsIDC~~YVCngn~rC~~LL~QYgs~C~~I~~aL~~v~~~~d~~~~~~~ 124 (605)
2741 T 6B3O_B 45 VQSVDGLYEMQIPTNFTIGHHEEFIQTRSPKVTIDCAAFVCGDNTACRQQLVEYGSFCVNVNAILNEVNNLLDNMQLQVA 124 (605)
2742 T ss_dssp -CBCSCCCCEEEEEEEEEEEEEEEEECSCCCCCCCHHHHHTCSCHHHHHHHTTSCSHHHHHHHHHHHC------------
2743 T ss_pred CcccCcceEEEecCceEeEEEEEEeeccCCCeEEehhhhccCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
2744 Confidence 45778888999999999999999999999999999999999999999999999999999999999999999999999999
2745
2746
2747 Q sp|P0DTC2|SPIK 783 AQVKQIYKTP-----PI-KDFGGFNFSQILPD-----------PSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIA 845 (1273)
2748 Q Consensus 783 aqvkqiyktp-----pi-kdfggfnfsqilpd-----------pskpskrsfiedllfnkvtladagfikqygdclgdia 845 (1273)
2749 ...++.+..+ .| ...|+||||.++|. |++|+.||+|||||||||..+|.|+.+.|..|.+...
2750 T Consensus 125 ~~~~~~~~~s~~~~~~i~~~~g~fN~s~ll~~~~~~~~~~~~~~~~~~~RSaIEDLLFnKVvt~glGt~~dYk~Ct~g~~ 204 (605)
2751 T 6B3O_B 125 SALMQGVTISSRLPDGISGPIDDINFSPLLGCIGSTCAEDGNGPSAIRGRSAIEDLLFDKVKLSDVGFVEAYNNCTGGQE 204 (605)
2752 T ss_dssp --------------------------------------------------------------------------------
2753 T ss_pred HHHhccCcccccCCCCCCCCCCCccchhhcccccCCcccCCCCCCcCCCccHHHHHHCCceEecCCchhHHHHhccCCcc
2754 Confidence 9998888764 22 33456999999986 7778899999999999999999999999999999999
2755
2756
2757 Q sp|P0DTC2|SPIK 846 ARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIAN 925 (1273)
2758 Q Consensus 846 ardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklian 925 (1273)
2759 .|||+|||.|||+.||||..++||++.||++|.+|....|||. |..||||+||.||+||+|+||+||.||||+|||
2760 T Consensus 205 iaDL~CAQyyNGImVLPpVvda~~~amYTaSL~G~ma~gG~Ta----AaaIPFa~~vQaRlNyvaltt~VLq~NQk~iAn 280 (605)
2761 T 6B3O_B 205 VRDLLCVQSFNGIKVLPPVLSESQISGYTTGATAAAMFPPWSA----AAGVPFSLSVQYRINGLGVTMNVLSENQKMIAS 280 (605)
2762 T ss_dssp ----------------------------------------------------------------------------CHHH
2763 T ss_pred hHHHhCccccCcEEeeCCCCCHHHHHHHHHHHHHHhhcccchh----cccCchHHHHHHHhcccccchHHHHHHHHHHHH
2764 Confidence 9999999999999999999999999999999999999999997 556899999999999999999999999999999
2765
2766
2767 Q sp|P0DTC2|SPIK 926 QFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQ 1005 (1273)
2768 Q Consensus 926 qfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslq 1005 (1273)
2769 .||.|+|.||+.++++++||.|+|||||++++||++|++||+.|||||||.++||.+|||++||++|+||||||||.+|.
2770 T Consensus 281 sFN~AignIq~gf~tta~AL~KIQdVVN~q~~aL~~Lt~QL~nNFgAISSSI~dIy~RLD~leAdaQVDRLItGRL~aLN 360 (605)
2771 T 6B3O_B 281 AFNNALGAIQDGFDATNSALGKIQSVVNANAEALNNLLNQLSNRFGAISASLQEILTRLEAVEAKAQIDRLINGRLTALN 360 (605)
2772 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
2773 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHH
2774 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
2775
2776
2777 Q sp|P0DTC2|SPIK 1006 TYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG 1085 (1273)
2778 Q Consensus 1006 tyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdg 1085 (1273)
2779 +||+|+|.+++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+||.||.|++|+|.+|+|.+-++.++.|.+|.++
2780 T Consensus 361 afVtQ~L~~~~eVr~sr~LA~qKINECVKSQS~RygFCGnGtHifSi~q~APnGi~FlH~~y~Pt~~~~V~A~~GlCv~~ 440 (605)
2781 T 6B3O_B 361 AYISKQLSDSTLIKVSAAQAIEKVNECVKSQTTRINFCGNGNHILSLVQNAPYGLYFIHFSYVPISFTTANVSPGLCISG 440 (605)
2782 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHTTTSSCCCCBSCSSSSEEEEEEEEEETTEEEEEEEEEEEEEEEEECCBSCEECSS
2783 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCccCcCCCCeEEEEeeeccCCeEEEEEEEecccceEEEEEEeeEEecC
2784 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999995
2785
2786
2787 Q sp|P0DTC2|SPIK 1086 -KAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDV 1164 (1273)
2788 Q Consensus 1086 -kahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydplqpeldsfkeeldkyfknhtspdv 1164 (1273)
2789 ++..|+.|+|+.+..+|++|.|++|+|..+|..|...-..|||...-++.++..|..|+.-.|++||+++|+|+++.-.
2790 T Consensus 441 ~~~~~~~~g~f~~~n~~~~iT~r~my~Pr~~t~~dfV~itSC~V~Y~Nvt~t~lp~viPdyiDfn~eLee~~~n~t~t~P 520 (605)
2791 T 6B3O_B 441 DRGLAPKAGYFVQDDGEWKFTGSSYYYPEPITDKNSVIMSSCAVNYTKAPEVFLNTSIPNPPDFKEELDKWFKNQTSIAP 520 (605)
2792 T ss_dssp SCEEEESSEEEEEETTEEEEEESSSCCCEECCTTSEEEESCSCCEEEECCCCCCCCCCCCCSCHHHHHTTTCCCCCCCCC
2793 T ss_pred CceEEecCeEEEeeCCeEEEeccccccCCCCCccceEEeeccccEEEecccccCCCCCCCCCChHHHHHHHHhcCCCCCC
2794 Confidence 7999999999999889999999999999999999999999999999999999999999999999999999999987444
2795
2796
2797 Q sp|P0DTC2|SPIK 1165 DLG-DISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 1203 (1273)
2798 Q Consensus 1165 dlg-disginasvvniqkeidrlnevaknlneslidlqel 1203 (1273)
2799 |+. |+.-+|+++.|+..||++|+++.|+||+++|||..-
2800 T Consensus 521 dl~~~ld~fN~T~LNLt~EI~~Lq~~i~~LN~s~IDL~~~ 560 (605)
2801 T 6B3O_B 521 DLSLDFEKLNVTLLDLTYEMNRIQDAIKKLNESYINLIKR 560 (605)
2802 T ss_dssp CCCCCGGGCCCCCCCCHHHHHHHHHHHHHTTTC-------
2803 T ss_pred CcCCCHHHccccccchHHHHHHHHHHHHHHHHHHHHHHHH
2804 Confidence 443 688999999999999999999999999999999754
2805
2806
2807 No 21
2808 >6PZ8_A S protein, G2 heavy chain; MERS-CoV, coronavirus, DPP4, receptor-binding, membrane; HET: MAN, NAG, BMA; 4.19A {Middle East respiratory syndrome-related coronavirus}
2809 Probab=100.00 E-value=8.5e-112 Score=897.44 Aligned_cols=445 Identities=43% Similarity=0.743 Sum_probs=424.4 Template_Neff=3.100
2810
2811 Q sp|P0DTC2|SPIK 694 AYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVE 773 (1273)
2812 Q Consensus 694 aytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiave 773 (1273)
2813 .|++.+-. ..+.+++..|.||+||||+|++|.++++|.|.+|||.+|+||++.+|.+||.|||+||..+|++|.|.+.+
2814 T Consensus 12 ~~~~p~~~-~~~~~~~~~i~IP~nFtl~v~~EyiQt~~~kV~IDC~~YVC~~~~~C~~LL~QYgs~C~~I~~aL~~~~~~ 90 (472)
2815 T 6PZ8_A 12 AFNHPIQV-DQLNSSYFKLSIPTNFSFGVTQEYIQTTIQKVTVDCKQYVCNGFQKCEQLLREYGQFCSKINQALHGANLR 90 (472)
2816 T ss_dssp CCCCCEEC-CCCCTTEEEEEECCEEEEEEEEEEEECCCCCEEECHHHHHSSSCHHHHHHHGGGHHHHHHHHHHHHHHHHH
2817 T ss_pred eccCCcee-ccccCCCeeEEeccceEEEEEEEEEEecCCceEEechhhccCCCHHHHHHHHHHHHHHHHHHHHHHHHHhh
2818 Confidence 56666554 67788899999999999999999999999999999999999999999999999999999999999999999
2819
2820
2821 Q sp|P0DTC2|SPIK 774 QDKNTQEVFAQVKQIYKTPPIKDF-GGFNFSQILPDPS---KPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDI--AAR 847 (1273)
2822 Q Consensus 774 qdkntqevfaqvkqiyktppikdf-ggfnfsqilpdps---kpskrsfiedllfnkvtladagfikqygdclgdi--aar 847 (1273)
2823 +|....+++...++-+..|-+..| |+|||+.++|.+. ++++||+||||||+||..+|.|+.+.|..|.... ..|
2824 T Consensus 91 ~d~~~~~~~s~~~~~~~~~~~~~~~g~fN~s~ll~~~~~~~~~~~RS~IEDLLF~KV~t~glG~~~~Yk~Ct~~~g~~i~ 170 (472)
2825 T 6PZ8_A 91 QDDSVRNLFASVKSSQSSPIIPGFGGDFNLTLLEPVSISTGSRSARSAIEDLLFDKVTIADPGYMQGYDDCMQQGPASAR 170 (472)
2826 T ss_dssp HHHHHHHHHHHHCCSEECCCCTTTTTTSCCTTSCCC--------CCCHHHHHHHHHSCCCCCCSSSCGGGGSSSSCTTCC
2827 T ss_pred ccHHHHHHHHhccccccCCCcCCCCCCcccceeccCcCCCCCCcceeHHHHHHcCceeecCCcchHhHHHHHhcCCccHH
2828 Confidence 999999999999999988887777 5799999999775 4458999999999999999999999999999544 899
2829
2830
2831 Q sp|P0DTC2|SPIK 848 DLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQF 927 (1273)
2832 Q Consensus 848 dlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqf 927 (1273)
2833 ||+|||.|||+.||||.+++||++.||++|.+|....|||+|..+|..||||+||.||+||+|+||+||.||||+|||.|
2834 T Consensus 171 DL~CaQyyNGi~VLPpv~d~~~~a~YTasL~g~ma~gg~T~GitsaaaIPFa~~vq~RlN~v~lt~~VL~~NQk~iA~sF 250 (472)
2835 T 6PZ8_A 171 DLICAQYVAGYKVLPPLMDVNMEAAYTSSLLGSIAGVGWTAGLSSFAAIPFAQSIFYRLNGVGITQQVLSENQKLIANKF 250 (472)
2836 T ss_dssp CTTTTHHHHTEEECCCSSHHHHHHHHHHHHHTTCSCSCSSCCSSCBCCCCHHHHHHHHHHTTTCCHHHHHHHHHHHHHHH
2837 T ss_pred HHhcccccCcEEEeCCCCCHHhHHHHHHHHHHHHHhcchhccchhhccCchHHHHHHHhhhhcccHHHHHHHHHHHHHHH
2838 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
2839
2840
2841 Q sp|P0DTC2|SPIK 928 NSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTY 1007 (1273)
2842 Q Consensus 928 nsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqty 1007 (1273)
2843 |.|||.||+.++++++||.|+|||||++++||++|++||+.|||||||.++||++|||++||++|+||||+|||.+|.+|
2844 T Consensus 251 N~Aig~iq~gf~tt~~AL~KiQ~VVN~q~~aL~~L~~qL~nnFgAISssI~dIy~RLD~leAdaQVDRLItGRL~aLnaf 330 (472)
2845 T 6PZ8_A 251 NQALGAMQTGFTTTNEAFHKVQDAVNNNAQALSKLASELSNTFGAISASIGDIIQRLDVLEQDAQIDRLINGRLTTLNAF 330 (472)
2846 T ss_dssp HHHHHTHHHHSSTTCHHHHHHHHHHHHHHHHHHHHHHGGGCCSSSSCSCHHHHHHHSCHHHHHHHHHHHHHHHHHHHHHH
2847 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHchHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHH
2848 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
2849
2850
2851 Q sp|P0DTC2|SPIK 1008 VTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHD--- 1084 (1273)
2852 Q Consensus 1008 vtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichd--- 1084 (1273)
2853 |+|+|.|++|+|+++.||..|+.|||..||+|.+|||.|.|++|+||.||+|++|+|.+|+|.+..+.++.|.+|++
2854 T Consensus 331 Vsq~l~~~~~v~~sr~LA~qKiNECVKSQS~R~gFCGnGtHi~Si~q~APnGi~F~H~~y~Pt~~~~V~a~~GlC~~~~~ 410 (472)
2855 T 6PZ8_A 331 VAQQLVRSESAALSAQLAKDKVNECVKAQSKRSGFCGQGTHIVSFVVNAPNGLYFMHVGYYPSNHIEVVSAYGLCDAANP 410 (472)
2856 T ss_dssp HHHHHHHHHHHHHHHHHHHHHCCCCCSSCCCCSSSSSSSSCEEEEEEEETTEEEEEEEEEEEECCEEEEEESCEEETTEE
2857 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHhcccccCCCCCCeeEEEEeeccCCeEEEEEEEEccCceeEEEEEeEEeecCCC
2858 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999995
2859
2860
2861 Q sp|P0DTC2|SPIK 1085 GKAHFPREGVFVSNG-----THWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDP 1140 (1273)
2862 Q Consensus 1085 gkahfpregvfvsng-----thwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp 1140 (1273)
2863 +++..|+.|+|+.+. ++|++|.|++|+|..||.+|+.. -.|||....+|+++++|
2864 T Consensus 411 ~~~~~p~~g~fv~~n~t~~~~~w~~T~r~~Y~P~~iT~~n~v~-~sc~vny~nv~~~~~~p 470 (472)
2865 T 6PZ8_A 411 TNCIAPVNGYFIKTNNTRIVDEWSYTGSSFYAPEPITSLNTKY-VAPQVTYQNISTNLPPP 470 (472)
2866 T ss_dssp EEEEEESSEEEEECCCTTCCSSEEEEESSSCCCEECCGGGEEE-CCCCTTSEEESSCCCTT
2867 T ss_pred CceEeecCceEEEeCCccccceEEEeccccccCcCCCccceEE-ecCcceEEEccccCCCC
2868 Confidence 578999999999866 46999999999999999999888 78899999999999998
2869
2870
2871 No 22
2872 >6PZ8_F S protein, G2 heavy chain; MERS-CoV, coronavirus, DPP4, receptor-binding, membrane; HET: BMA, MAN, NAG; 4.19A {Middle East respiratory syndrome-related coronavirus}
2873 Probab=100.00 E-value=3.1e-74 Score=636.33 Aligned_cols=621 Identities=20% Similarity=0.314 Sum_probs=345.6 Template_Neff=4.300
2874
2875 Q sp|P0DTC2|SPIK 14 QCVNL-TTRTQLPPAYT----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG--T-------KRF 79 (1273)
2876 Q Consensus 14 qcvnl-ttrtqlppayt----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng--t-------krf 79 (1273)
2877 .|... -...-+++.++ -+-.+|+||||..++++..+-.|+||.+.-++.+-.- ++|++. + -.+
2878 T Consensus 12 ~C~~~~~~~~~~~~~~s~~idvs~~~G~yYp~~rvysN~tll~~glfp~~gs~~~~y~---~~~~~~~~~~~~~~~~~~y 88 (726)
2879 T 6PZ8_F 12 ACIEVDIQQTFFDKTWPRPIDVSKADGIIYPQGRTYSNITITYQGLFPYQGDHGDMYV---YSAGHATGTTPQKLFVANY 88 (726)
2880 T ss_dssp BCCCEEECGGGGCCCCCCCCCGGGTTTCBCCSSCEECSEEEEEEEEECCTTCCCEEEC---CEECCBCSSSBCSEEECSC
2881 T ss_pred ceEEecccccccCCCCCcceecccCceeEeeCCeeEeeeeeeecccccCCCCcceEEE---EeecCCCCCCCccceeecC
2882 Confidence 36655 23334445555 3446899999999999999999999999988876532 333332 2 356
2883
2884
2885 Q sp|P0DTC2|SPIK 80 DNPVLPFNDGVYFASTEKSNIIR-----------------GWIFGTTLDSKT---Q------SLLIVNNATNVVI----- 128 (1273)
2886 Q Consensus 80 dnpvlpfndgvyfasteksniir-----------------gwifgttldskt---q------sllivnnatnvvi----- 128 (1273)
2887 +.+..||+||+++...+..|.-. .++||+|.+... + +++|+++-.+.++
2888 T Consensus 89 ~~~~~~F~dGifvkv~~~~n~t~~~~~~~~~~~~~~~~ypa~~fGstf~n~s~~~~~~~~~~tlvI~P~~~g~~~~~~~c 168 (726)
2889 T 6PZ8_F 89 SQDVKQFANGFVVRIGAAANSTGTVIISPSTSATIRKIYPAFMLGSSVGNFSDGKMGRFFNHTLVLLPDGCGTLLRAFYC 168 (726)
2890 T ss_dssp TTCCEECTTCEEEEECTTTTCEEECSSSTTCEEEEECCCCCEEEESCEECCTTSCSCEECSEEEEEEEETTTTEEEEEEE
2891 T ss_pred CCChHHccCeEEEEEeeeeccCCCeeeCCCcccchhhcccceEEeccccCCCCccceeeeceEEEEecCCCCccceeeee
2892 Confidence 77889999999998887666532 256999998766 6 8999999887654
2893
2894
2895 Q sp|P0DTC2|SPIK 129 --KVCEFQFCNDPFLGVYYHKNN---KSWME---------SEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVF 194 (1273)
2896 Q Consensus 129 --kvcefqfcndpflgvyyhknn---kswme---------sefrvyssannctfeyvsqpflmdlegkqgnfknlrefvf 194 (1273)
2897 ...+..-|..|..-+++.-+. .+|-. -+++.|....||+|.|. +.|-+|... ..|- |.|
2898 T Consensus 169 ~~~prt~t~C~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~-~nft~d~~~--~wf~----~~F 241 (726)
2899 T 6PZ8_F 169 ILEPRSGNHCPAGNSYTSFATYHTPATDCSDGNYNRNASLNSFKEYFNLRNCTFMYT-YNITEDEIL--EWFG----ITQ 241 (726)
2900 T ss_dssp EEEECCSBTSTTSTTCCCCCEEECHHHHEETTEECTTHHHHHHHHHEEEEEEEEEEE-EECCCCCCC--EEEE----EEE
2901 T ss_pred ecccCccccCCCCCeEeeecccCCCCccCCCCcccccccccchhhheecCCcEEEEe-eecCcchhh--heEE----EEE
2902 Confidence 323344555666655542221 23422 36788899999999875 344333211 1111 999
2903
2904
2905 Q sp|P0DTC2|SPIK 195 KNID-GYFKIYSKHTPINL---VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYL 270 (1273)
2906 Q Consensus 195 knid-gyfkiyskhtpinl---vrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgyl 270 (1273)
2907 +..| |.|-+|..++..+. ..-+| |...+.+.. .+-|+..++ .+.+. .-++|||++|
2908 T Consensus 242 ~~~~~G~f~~Y~~d~~~~~~f~f~~~~-~~~~~~yy~---------------vip~~~~~~---~~~~~-~~~~~yV~~L 301 (726)
2909 T 6PZ8_F 242 TAQGVHLFSSRYVDLYGGNMFQFATLP-VYDTIKYYS---------------IIPHSIRSI---QSDRK-AWAAFYVYKL 301 (726)
2910 T ss_dssp ETTEEEEEESTTTCTTTCCBEEEEEEC-CCSCCCEEE---------------ECCEEECCC---GGGCC-EECCEEEEEC
2911 T ss_pred eeCCceeEEEEEEecCCCcceeccccc-ceeccceee---------------eeeeeecCC---cccce-eEEEEEEEEc
2912 Confidence 9999 99999877655442 22233 444444443 333444444 45566 7889999999
2913
2914
2915 Q sp|P0DTC2|SPIK 271 QPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASV 350 (1273)
2916 Q Consensus 271 qprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasv 350 (1273)
2917 .+|+|||+|+.||.|++||||+-|+++|-||..+||.+++|+|++|+||+||....+|.++. ..|+|.++++ .++.++
2918 T Consensus 302 ~~~~yLl~Fd~nG~It~AvDCa~d~~sEL~Cst~Sf~p~tGVY~lS~y~aqP~g~V~~~~~~-~~C~~~~~~~-~~~Psp 379 (726)
2919 T 6PZ8_F 302 QPLTFLLDFSVDGYIRRAIDCGFNDLSQLHCSYESFDVESGVYSVSSFEAKPSGSVVEQAEG-VECDFSPLLS-GTPPQV 379 (726)
2920 T ss_dssp EEEEEEEEECTTSCEEEEEETTSSHHHHHHHHTSSSSSSCSCEEEEEECCCCEEEEEECCC-------------------
2921 T ss_pred ccceEEEecCCCCeEEEEEeccCCccccceeEeeeecCCCCeeecCcEEEEeeeEEEEecCC-CCCCChHHhc-CCCCCc
2922 Confidence 99999999999999999999999999999999999999999999999999999999999999 9999999999 889999
2923
2924
2925 Q sp|P0DTC2|SPIK 351 YAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFT 430 (1273)
2926 Q Consensus 351 yawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddft 430 (1273)
2927 +.|.|+.++||..|+++|++....+.|+||||+|.||.+.||..|++|.|.|..+..++++||++|-|++||||+|++|+
2928 T Consensus 380 ~~w~R~~fsNCnfN~s~Lls~~~~~~f~C~gIspskLa~mCfsSvtiD~Faip~s~~~~L~~g~~g~i~~yNYkld~~~~ 459 (726)
2929 T 6PZ8_F 380 YNFKRLVFTNCNYNLTKLLSLFSVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVSSAGPISQFNYKQSFSNP 459 (726)
2930 T ss_dssp --------------------------------------------------------------------------------
2931 T ss_pred ceeeEEEEecccccHHHHHhccceeeeeecCCCHHHHhhhccceeeEEEEEcchhhccccCCCCCccchhccccCCCCCC
2932 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
2933
2934
2935 Q sp|P0DTC2|SPIK 431 GCVIAWNSNNLDSK--VGGNYNYLYRLFRKSNLKPFERDISTEIYQAG--STPCN--GVEGFNCYFPLQS---------- 494 (1273)
2936 Q Consensus 431 gcviawnsnnldsk--vggnynylyrlfrksnlkpferdisteiyqag--stpcn--gvegfncyfplqs---------- 494 (1273)
2937 ||+++|+-.+++.. --.+|+|+-|-.+... ++. +++-|-- .+-|+ ... -+|+.+...
2938 T Consensus 460 ~C~l~~~~~~~~~n~t~~~~~~~i~~~~~~~~-----~~~-~~~~~~~~~~~~cpc~~~~-~~~~~~~~~~~~~~~~~~~ 532 (726)
2939 T 6PZ8_F 460 TCLILATVPHNLTTITKPLKYSYINKCSRLLS-----DDR-TEVPQLVNANQYSPCVSIV-PSTVWEDGDYYRKQLSPLE 532 (726)
2940 T ss_dssp --------------------------------------------------------------------------------
2941 T ss_pred ceEEEEEcCcccccCCCcccceeeeeeccCCC-----CCC-cchhhhccccccCCCcccC-CccccCCCCcccccccccc
2942 Confidence 99999985442222 2567777776666443 222 2221100 11111 000 112221111
2943
2944
2945 Q sp|P0DTC2|SPIK 495 -YGFQP----TNGVGYQPYRVVVLSFELLHAPATVCGPK-----KSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQ 564 (1273)
2946 Q Consensus 495 -ygfqp----tngvgyqpyrvvvlsfellhapatvcgpk-----kstnlvknkcvnfnfngltgtgvltesnkkflpfqq 564 (1273)
2947 -+..+ ..++++|.+.+++++++..-.+.|||..+ ..++++.++||++|..|.+|+||++++|..+...+.
2948 T Consensus 533 ~~~~~~~~~~~~~~~~~c~~lvvIt~~~gs~~~TvcP~~~~~~~~~s~i~l~~Cv~YnIYG~tG~GvI~~~n~~~~~gl~ 612 (726)
2949 T 6PZ8_F 533 GGGWLVASGSTVAMTEQLQMGFGITVQYGTDTNSVCPKLEFANDTKIASQLGNCVEYSLYGVSGRGVFQNCTAVGVRQQR 612 (726)
2950 T ss_dssp -------------------------------------------CCSCSCCCSSSEEEEETTEEEEECEEECCCCSCTTSC
2951 T ss_pred CCccccccccceecccceeEEEEEEeecCCCccccccccccccCCceeeeeCeeeeEEeCCceeeEEEEecCeeeeCCEE
2952 Confidence 12222 34889999999999999999999999442 247999999999999999999999999999999999
2953
2954
2955 Q sp|P0DTC2|SPIK 565 FGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRV--YSTGSNV 642 (1273)
2956 Q Consensus 565 fgrdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrv--ystgsnv 642 (1273)
2957 +..+.+.-.-++++ .++++..|+||..+.++++..|+ ++.++.||..++|+.+....+..+.+|.||+ +++..+.
2958 T Consensus 613 ~~~s~sg~l~~fk~-~~g~~Y~V~PC~~v~~qvvv~~~--s~~~vgl~ts~nc~~v~~~~~~~~~s~~~~~~~~~~~~~~ 689 (726)
2959 T 6PZ8_F 613 FVYDAYQNLVGYYS-DDGNYYCLRACVSVPVSVIYDKE--TKTHATLFGSVACEHISSTMSQYSRSTRSMLKRRDSTYGP 689 (726)
2960 T ss_dssp EEECTTSCEEEEEC-TTSCEEEECCCCCEEEEEEEETT--TTEEEEECGGGCGGGCCSSCSSCSSSCCHHHHHHHTTSCC
2961 T ss_pred EEecCCCCEEEEEe-CCCCEEEEecCcccceeEEEeCC--CCCEEEEEecccCccccccceeeccCCchhcccccCCCCC
2962 Confidence 97788888999999 99999999999999999999997 7889999999999999999999999999998 8888899
2963
2964
2965 Q sp|P0DTC2|SPIK 643 FQTRAGCLIGAEHVNN-SYECDIPIGAGICASYQT 676 (1273)
2966 Q Consensus 643 fqtragcligaehvnn-syecdipigagicasyqt 676 (1273)
2967 |||-+||++||++.+. ..|||+|+|+|+||.|.+
2968 T Consensus 690 fdT~~GCV~na~n~t~~V~~C~LplG~slC~~~~~ 724 (726)
2969 T 6PZ8_F 690 LQTPVGCVLGLVNSSLFVEDCKLPLGQSLCALPDT 724 (726)
2970 T ss_dssp EECSSCEEETCCEEEEEESCCSSEEETTEEEECCC
2971 T ss_pred CCCchheeeeeecCCCceeeCCCCCCcceecCCCC
2972 Confidence 9999999999999998 999999999999999976
2973
2974
2975 No 23
2976 >7BZ5_A Spike protein S1, Heavy chain; covid-19 antibody, VIRAL PROTEIN, VIRAL; HET: NAG; 1.84A {Severe acute respiratory syndrome coronavirus 2}
2977 Probab=100.00 E-value=3.5e-52 Score=416.50 Aligned_cols=225 Identities=99% Similarity=1.598 Sum_probs=190.3 Template_Neff=4.100
2978
2979 Q sp|P0DTC2|SPIK 319 RVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYAD 398 (1273)
2980 Q Consensus 319 rvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyad 398 (1273)
2981 |+||...++|++++++.|+|.++|+|.++.++|+|.|+.++||..|+++|++..++++|+||||||+||.++||.+|++|
2982 T Consensus 1 raqP~g~V~r~~~~~~~C~~~~~l~~~~~Psp~nW~R~~fsNCnfn~s~Lls~~~~~sf~C~gIspskL~~mCfsSvtiD 80 (229)
2983 T 7BZ5_A 1 RVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYAD 80 (229)
2984 T ss_dssp ---------------CBCCHHHHHTCSSCCBGGGCEEEEECSEECCCHHHHSCSCCSEEEEESSCSTTCTTCEESEEEEE
2985 T ss_pred CcccceEEEECCCCCCCCChHHHhcCCCCCCchheEEeEEecCCCcHHHHhhcceeceeeEeCCCHHHHcccccCeeEEE
2986 Confidence 78999999999999999999999999999999999999999999999999999999999999999999999999999999
2987
2988
2989 Q sp|P0DTC2|SPIK 399 SFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGST 478 (1273)
2990 Q Consensus 399 sfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagst 478 (1273)
2991 .|.|+++++++++||++|.|++||||||+||+||+|+|+..+++..+.++|||++|.+++++++|||||++.++|+++.+
2992 T Consensus 81 ~Faip~s~~~~L~~G~sG~i~~yNYKlp~~f~gC~l~~~~~~~~~~vt~~~~y~~rr~~~~~~~~f~~~~~~~~y~~~~~ 160 (229)
2993 T 7BZ5_A 81 SFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGST 160 (229)
2994 T ss_dssp EEEEEGGGGGGSSTTCCSHHHHHTCCCCTTCCEEEEEEECHHHHCCTTCBCCCEEECCCSSCCCTTCCCCCCCCEECSSS
2995 T ss_pred EEEecccceeecCCCCCcHHHhcccCCCCCCCCeEEEEEeCCcccccccchHHHHHhccccCCCccccCCccceeccCCC
2996 Confidence 99999999999999999999999999999999999999999999888899999999999999999999999999999999
2997
2998
2999 Q sp|P0DTC2|SPIK 479 PCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNF 543 (1273)
3000 Q Consensus 479 pcngvegfncyfplqsygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnf 543 (1273)
3001 .|++..+.+|+.|+..|++|++.|+|+|+|+|+|++++...+++|||++|.+|++++++||||..
3002 T Consensus 161 ~c~~~~~~~c~~p~~~~~~~~~~g~g~~c~g~~Vis~k~~~~s~TVC~~~~~T~~v~g~~~~~~~ 225 (229)
3003 T 7BZ5_A 161 PCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFHH 225 (229)
3004 T ss_dssp CCTTCCBTTEECSEEECCBCTTBCGGGSEEEEEEEEEECC-CCCCEECCC---------------
3005 T ss_pred CCCCCCcccceeccCCCCCcccccccccceEEEEEEEEccCCCCccCCCCCCHHHhcCeeecCCC
3006 Confidence 99955599999999999988899999999999999999999999999999999999999999964
3007
3008
3009 No 24
3010 >6YZ5_E Spike glycoprotein, Nanobody H11-D4; nanobody, complex, SARS-Cov-2, VIRAL PROTEIN; HET: NAG, EDO, ACT; 1.8A {Severe acute respiratory syndrome coronavirus 2}
3011 Probab=100.00 E-value=3.5e-51 Score=405.64 Aligned_cols=205 Identities=99% Similarity=1.601 Sum_probs=193.3 Template_Neff=3.900
3012
3013 Q sp|P0DTC2|SPIK 330 PNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQ 409 (1273)
3014 Q Consensus 330 pnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrq 409 (1273)
3015 ||+++.|+|.++|+|.++.|+|+|.|+.++||+.|+|+|+++.++++|+||||||+||.++||.+|++|.|.|+++++++
3016 T Consensus 1 ~~~~~~C~~~~~l~~~~~Psp~nWeR~~fsNCnfNlS~Lls~~~~~sF~C~gIspskLa~mCfsSVtiD~Faip~s~~~d 80 (210)
3017 T 6YZ5_E 1 PNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQ 80 (210)
3018 T ss_dssp ----CBCCHHHHHTCSSCCBGGGCEEEEECSEECCTHHHHTCSSCSEEEEESCCHHHHTTCEESEEEEEEEEEEGGGGGG
3019 T ss_pred CCCcCCCCHHHHhcCCCCCCchheEEeEEecCCCcHHHHhhcceeceeeeeCCCHHHHcccccCeeEEEEEEecccceee
3020 Confidence 78899999999999999999999999999999999999999999999999999999999999999999999999999999
3021
3022
3023 Q sp|P0DTC2|SPIK 410 IAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCY 489 (1273)
3024 Q Consensus 410 iapgqtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncy 489 (1273)
3025 ++||++|.|++||||||+||+||+|+|+..+++..+.++|||++|.+++++++||||+++.++|+++.+.|++..+.||+
3026 T Consensus 81 Lq~G~sG~i~~yNYKlp~~f~gC~l~~~~~~~~vnvts~yny~~rr~~~~~~~~f~~~~~~~~y~~~~~~c~~~~~~~c~ 160 (210)
3027 T 6YZ5_E 81 IAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCY 160 (210)
3028 T ss_dssp SSTTCCSHHHHHTCCCCTTCCEEEEEEECHHHHCCTTCBCCCEEECCCSSCCCTTCCCCCCCCEECSSSCCTTCCBTTEE
3029 T ss_pred cCCCCCcHHHhcccCCCCCCCCeEEEEEeCCccccccccHHHHHHhcccCCCCccccccccchhccCCCCCCCCccccce
3030 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999955599999
3031
3032
3033 Q sp|P0DTC2|SPIK 490 FPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLV 534 (1273)
3034 Q Consensus 490 fplqsygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlv 534 (1273)
3035 .|+..|++|.+.|+|+|+|+|+|++++.+++|+||||||+|||.-
3036 T Consensus 161 ~p~~~~~~~~~~g~g~~c~gv~Vis~k~~~~~~t~~~~~~~~~~~ 205 (210)
3037 T 6YZ5_E 161 FPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNKH 205 (210)
3038 T ss_dssp CSEEECCBCTTSCGGGSEEEEEEEEEECCSSCCCEECCCCT----
3039 T ss_pred ecccCCCCCCcccCCccceEEEEEEEEcCCCceEEeCcccccCCC
3040 Confidence 999998988899999999999999999999999999999999853
3041
3042
3043 No 25
3044 >6YLA_E SARS-CoV-2 RBD, Heavy Chain, Light; SARS-CoV-2 Spike protein, RBD, CR3022; HET: DMS, MLI, 1PE, NAG; 2.42A {Severe acute respiratory syndrome coronavirus 2}
3045 Probab=100.00 E-value=3.8e-51 Score=406.04 Aligned_cols=207 Identities=98% Similarity=1.577 Sum_probs=201.0 Template_Neff=3.900
3046
3047 Q sp|P0DTC2|SPIK 328 RFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEV 407 (1273)
3048 Q Consensus 328 rfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdev 407 (1273)
3049 .||++++.|+|.++|||.++.|+|+|.|+.++||+.|+|+|+++.++++|+||||||+||.++||.+|++|.|.|+++++
3050 T Consensus 2 ~~~~~~~~C~~~~~l~~~~~Psp~nWeR~~fsNCnfNlS~Lls~~~~~sF~C~gIspskLa~mCfsSVtiD~Faip~s~~ 81 (213)
3051 T 6YLA_E 2 TGPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEV 81 (213)
3052 T ss_pred CCCCCcCCCCHHHHhcCCCCCCchheEEeEEecCCCcHHHHhhcceeceeeeeCCCHHHHcccccCeeEEEEEEecccce
3053 Confidence 47999999999999999999999999999999999999999999999999999999999999999999999999999999
3054
3055
3056 Q sp|P0DTC2|SPIK 408 RQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFN 487 (1273)
3057 Q Consensus 408 rqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfn 487 (1273)
3058 ++++||++|.|++||||||+||+||+|+|+..+++..+.++|||++|.+++++++||||+++.++|+++.+.|++..+.|
3059 T Consensus 82 ~dLq~G~sG~i~~yNYKlp~~f~gC~l~~~~~~~~vnvts~yny~~rr~~~~~~~~f~~~~~~~~y~~~~~~c~~~~~~~ 161 (213)
3060 T 6YLA_E 82 RQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFN 161 (213)
3061 T ss_pred eecCCCCCcHHHhcccCCCCCCCCeEEEEEeCCccccccccHHHHHHhcccCCCCccccccccchhccCCCCCCCCcccc
3062 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999555999
3063
3064
3065 Q sp|P0DTC2|SPIK 488 CYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLV 534 (1273)
3066 Q Consensus 488 cyfplqsygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlv 534 (1273)
3067 ||.|+..|++|.+.|+|+|+|+|+|++++.+++|+||||||+|||.-
3068 T Consensus 162 c~~p~~~~~~~~~~g~g~~c~gv~Vis~k~~~~~~t~~~~~~~~~~~ 208 (213)
3069 T 6YLA_E 162 CYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNKH 208 (213)
3070 T ss_pred ceecccCCCCCCcccCCccceEEEEEEEEcCCCceEEeCcccccCCC
3071 Confidence 99999998988899999999999999999999999999999999853
3072
3073
3074 No 26
3075 >6ZFO_A SARS-CoV-2 RBD, Nanobody, EY6A heavy; EY6a, RBD, Spike glycoprotein, SARS-CoV-2; HET: NAG;{Severe acute respiratory syndrome coronavirus 2}
3076 Probab=100.00 E-value=2.3e-47 Score=375.21 Aligned_cols=194 Identities=100% Similarity=1.634 Sum_probs=189.3 Template_Neff=4.100
3077
3078 Q sp|P0DTC2|SPIK 333 TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAP 412 (1273)
3079 Q Consensus 333 tnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiap 412 (1273)
3080 |+.|+|.++|||.++.++|+|.||.++||+.|+|+|+++.++++|+||||+|+||.++||.+|++|.|.|+++++++++|
3081 T Consensus 1 ~~~C~~~~~l~~~~~Psp~nWeR~~fsNCnfn~S~Lls~~~~~sf~C~gIspskL~~mCfsSvtiD~Faip~s~~~~L~~ 80 (194)
3082 T 6ZFO_A 1 TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAP 80 (194)
3083 T ss_dssp CCBCCCHHHHSCSSCCCSTTCEEEEECSEECCTHHHHHCCCCSEEEEESSCSGGGTTCCBSEEEEEEEEEEHHHHTTSST
3084 T ss_pred CCCCCHHHhhccCCCCCchheEEeEEecCCCcHHHHhhcceeceeeeeCCCHHHHcccccCeeEEEEEEecccceeecCC
3085 Confidence 57899999999999999999999999999999999999999999999999999999999999999999999999999999
3086
3087
3088 Q sp|P0DTC2|SPIK 413 GQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPL 492 (1273)
3089 Q Consensus 413 gqtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfpl 492 (1273)
3090 |++|.|++||||||+||+||+|+|+..+++..+.++|||++|.+++++++||||+++.++|+++.+.|++..+.||+.|+
3091 T Consensus 81 G~sG~i~~yNYKlp~~f~gC~l~~~~~~~~~nvt~~y~y~~~~~~~~~~~~f~~~~~~~~y~~~~~~c~~~~~~~c~~p~ 160 (194)
3092 T 6ZFO_A 81 GQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPL 160 (194)
3093 T ss_dssp TCCSHHHHHTCCCCTTCCEEEEEEECTTTSCCTTCBCCCEEECCCSSCCCTTCCCCCCCCEECSSSCCSSCCBTTEECSE
3094 T ss_pred CCCcHHHhcccCCCCCCCCeEEEEEeCCccccccccHHHHHHhcccCCCCccccccccchhccCCCCCCCCccccceecc
3095 Confidence 99999999999999999999999999999999999999999999999999999999999999999999955599999999
3096
3097
3098 Q sp|P0DTC2|SPIK 493 QSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCG 526 (1273)
3099 Q Consensus 493 qsygfqptngvgyqpyrvvvlsfellhapatvcg 526 (1273)
3100 ..|++|++.|+|+|+|+|+|++++.+|+|+||||
3101 T Consensus 161 ~~~~~~~~~g~g~~c~g~~Vis~k~~~~~~t~~~ 194 (194)
3102 T 6ZFO_A 161 QSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCG 194 (194)
3103 T ss_dssp EECCBCTTSCTTTSEEEEEEEEEECCSSCCCEEC
3104 T ss_pred cCCCCCCcccCCccceEEEEEEEEcCCCcceecC
3105 Confidence 9989888999999999999999999999999998
3106
3107
3108 No 27
3109 >2GHV_C Spike glycoprotein; SARS, S protein, VIRAL PROTEIN; 2.2A {SARS coronavirus} SCOP: d.318.1.1
3110 Probab=100.00 E-value=3.9e-37 Score=305.00 Aligned_cols=197 Identities=71% Similarity=1.226 Sum_probs=171.8 Template_Neff=4.000
3111
3112 Q sp|P0DTC2|SPIK 330 PNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQ 409 (1273)
3113 Q Consensus 330 pnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrq 409 (1273)
3114 |+++..|+|.++|+|.++.++|+|.|+.++||..|+|+|++..++++|+||||||+||.++||..|++|.|.|..+++++
3115 T Consensus 4 ~~~~~~C~~~~~l~~~~~Psp~nWeR~~fsNCnfnls~Lls~~~~~sf~C~gIspskLa~mCfsSvtiD~Faip~s~~~~ 83 (203)
3116 T 2GHV_C 4 PNITNLCPFGEVFNATKFPSVYAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFSNVYADSFVVKGDDVRQ 83 (203)
3117 T ss_dssp ---CCBCCCHHHHSCSSCCBGGGCEEEEECSSBCCGGGSCSCCBCSEEEEESCBGGGGGGGGCSSEEEEEEEEEGGGGGG
3118 T ss_pred CCccCCCCHHHHhcCCCCCCcceeEEeEEecCCCCHHHHhhccccceeeeeCCCHHHHcccccCeeEEEEEEeccchhhh
3119 Confidence 67789999999999999999999999999999999999999999999999999999999999999999999999999999
3120
3121
3122 Q sp|P0DTC2|SPIK 410 IAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCY 489 (1273)
3123 Q Consensus 410 iapgqtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncy 489 (1273)
3124 ++||++|-|++||||||+||+||+++|+-.+++..+.+|||+.++-.|...++|+++|++.-.+-.+..||....-.+|+
3125 T Consensus 84 Lq~G~sG~i~~yNYKlp~~f~gC~l~~~~~~~~vn~t~~~nps~~~~r~~~~~~~~~~~c~c~~~~~~~~c~~~~~~~p~ 163 (203)
3126 T 2GHV_C 84 IAPGQTGVIADYNYKLPDDFMGCVLAWNTRNIDATSTGNYNYKYRYLRHGKLRPFERDISNVPFSPDGKPCTPPALNCYW 163 (203)
3127 T ss_dssp SSTTCCSHHHHHTCCCCTTCCEEEEEEECHHHHCBTTCBCCCEEECCCSSCCCTTCCCCCCCCBCTTSCCCCTTSTTCBC
3128 T ss_pred cCCCCCcHHHhcccCCCCCCcceEEEEEeCccccccCCccCcccchhcccccccCCCccCCCCCCCCCCCCCCCCccccc
3129 Confidence 99999999999999999999999999999888888888788777665555689999999986664444566543333334
3130
3131
3132 Q sp|P0DTC2|SPIK 490 FPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGP 527 (1273)
3133 Q Consensus 490 fplqsygfqptngvgyqpyrvvvlsfellhapatvcgp 527 (1273)
3134 .|-. +++..+.|+|+|+|+|+|++++.+.+|+||||-
3135 T Consensus 164 ~~~~-~~~~~~~g~g~~c~g~~Vis~k~~~~~~t~~~~ 200 (203)
3136 T 2GHV_C 164 PLND-YGFYTTTGIGYQPYRVVVLSFELLNAPATVSGL 200 (203)
3137 T ss_dssp CEEE-CCBBSSSCGGGSEEEEEEEEECSGGSTCBTTCC
3138 T ss_pred CCCc-CCceecccCCccceEEEEEEEEcCCCceEEeee
3139 Confidence 4322 556677899999999999999999999999994
3140
3141
3142 No 28
3143 >1WYY_A E2 Glycoprotein; membrane fusion, severe acute respiratory; 2.2A {SARS coronavirus} SCOP: h.3.3.1
3144 Probab=100.00 E-value=2.3e-36 Score=288.46 Aligned_cols=99 Identities=89% Similarity=1.142 Sum_probs=83.9 Template_Neff=2.300
3145
3146 Q sp|P0DTC2|SPIK 903 AYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILS 982 (1273)
3147 Q Consensus 903 ayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndils 982 (1273)
3148 +||+|++|++++||.||||+||+.||.|++.|+..++++++||.|+|||||++++||+.|+.||+.|||||||.++||.+
3149 T Consensus 3 ~~RlNyvalqt~VLq~NQk~iA~sFN~Ai~~i~~gf~tts~AL~KIQdVVN~q~~aL~~Lt~QL~nNFgAISSSI~dIy~ 82 (149)
3150 T 1WYY_A 3 AYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILS 82 (149)
3151 T ss_dssp -----CCSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
3152 T ss_pred ccccchhhhcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHH
3153 Confidence 69999999999999999999999999999999999999999999999999999999999999999999999999999999
3154
3155
3156 Q sp|P0DTC2|SPIK 983 RLDKVEAEVQIDRLITGRL 1001 (1273)
3157 Q Consensus 983 rldkveaevqidrlitgrl 1001 (1273)
3158 |||++||.+|+|||||||+
3159 T Consensus 83 RLD~leAdaQVDRLItGR~ 101 (149)
3160 T 1WYY_A 83 RLDKVEAEVQIDRLITGGR 101 (149)
3161 T ss_dssp HHHHHHHHC----------
3162 T ss_pred HHHHHHHHHHHHHHHhcCC
3163 Confidence 9999999999999999985
3164
3165
3166 No 29
3167 >1WYY_B E2 Glycoprotein; membrane fusion, severe acute respiratory; 2.2A {SARS coronavirus} SCOP: h.3.3.1
3168 Probab=100.00 E-value=2.3e-36 Score=288.46 Aligned_cols=99 Identities=89% Similarity=1.142 Sum_probs=81.9 Template_Neff=2.300
3169
3170 Q sp|P0DTC2|SPIK 903 AYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILS 982 (1273)
3171 Q Consensus 903 ayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndils 982 (1273)
3172 +||+|++|++++||.||||+||+.||.|++.|+..++++++||.|+|||||++++||+.|+.||+.|||||||.++||.+
3173 T Consensus 3 ~~RlNyvalqt~VLq~NQk~iA~sFN~Ai~~i~~gf~tts~AL~KIQdVVN~q~~aL~~Lt~QL~nNFgAISSSI~dIy~ 82 (149)
3174 T 1WYY_B 3 AYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILS 82 (149)
3175 T ss_dssp -------CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
3176 T ss_pred ccccchhhhcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHH
3177 Confidence 69999999999999999999999999999999999999999999999999999999999999999999999999999999
3178
3179
3180 Q sp|P0DTC2|SPIK 983 RLDKVEAEVQIDRLITGRL 1001 (1273)
3181 Q Consensus 983 rldkveaevqidrlitgrl 1001 (1273)
3182 |||++||.+|+|||||||+
3183 T Consensus 83 RLD~leAdaQVDRLItGR~ 101 (149)
3184 T 1WYY_B 83 RLDKVEAEVQIDRLITGGR 101 (149)
3185 T ss_dssp HHHHHHHHC----------
3186 T ss_pred HHHHHHHHHHHHHHHhcCC
3187 Confidence 9999999999999999985
3188
3189
3190 No 30
3191 >5X4S_A Spike glycoprotein; SARS-CoV, spike, N-terminal domain, VIRAL; HET: NAG; 2.2A {Human SARS coronavirus}
3192 Probab=100.00 E-value=1.1e-34 Score=297.96 Aligned_cols=261 Identities=56% Similarity=1.068 Sum_probs=238.0 Template_Neff=4.200
3193
3194 Q sp|P0DTC2|SPIK 30 NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTT 109 (1273)
3195 Q Consensus 30 nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgtt 109 (1273)
3196 -|-.+|+||||..+||+..+-.|+||.++-++++-+|. .--.+++++.||+||+++...+++|.-++|+||+|
3197 T Consensus 21 ~s~~~G~yYPd~~~ysN~t~L~qglfp~~gs~~~~~~~-------~~~~y~~~~~~F~dGifv~v~~~~n~t~a~~fGst 93 (285)
3198 T 5X4S_A 21 TSSMRGVYYPDEIFRSDTLYLTQDLFLPFYSNVTGFHT-------INHTFDNPVIPFKDGIYFAATEKSNVVRGWVFGST 93 (285)
3199 T ss_pred cccCceeEecCCeeeecceeeeecccCCCCCCccccCC-------cceecCCCccccCCeEEEEeeeecCCCCceeeeec
3200 Confidence 34568999999999999999999999999999998555 23568899999999999999999999889999999
3201
3202
3203 Q sp|P0DTC2|SPIK 110 LDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNL 189 (1273)
3204 Q Consensus 110 ldsktqsllivnnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknl 189 (1273)
3205 .+.++++++|+++-+...|.+|.|+.|..|.+.++..-.| --++..|..+.||+|+|.|+.|-+|...+-.+....
3206 T Consensus 94 f~N~s~tviI~p~~~~~~it~C~~~vC~~p~~~~~~~~g~----~~~~~~f~~~~nc~~~~~~~nfT~d~~~~~~~~~~r 169 (285)
3207 T 5X4S_A 94 MNNKSQSVIIINNSTNVVIRACNFELCDNPFFAVSKPMGT----QTHTMIFDNAFNCTFEYISDAFSLDVSEKSGNFKHL 169 (285)
3208 T ss_pred ccCCcEEEEEcCCCCcceEEEeEEEeCCCCeeEEcCCCCc----ccccceeeecCCCeEEEcccccccccCcceeeeeeE
3209 Confidence 9999999999999999999999999999999998874333 567888999999999999999999988888888889
3210
3211
3212 Q sp|P0DTC2|SPIK 190 REFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGY 269 (1273)
3213 Q Consensus 190 refvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgy 269 (1273)
3214 ++|+|++.||+|-+|....+.+..+.+|.|+..|.|..-+|..|+||.|...+ |.|-++ .+.|..+.++|||++
3215 T Consensus 170 ~~f~F~~~dG~f~~Y~~~~~~~~f~~~p~~~~~l~yy~vip~s~~~~~~~~~~---~~~~~~---~~~~~~~~~a~yV~~ 243 (285)
3216 T 5X4S_A 170 REFVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIFKLPLGINITNFRAIL---TAFSPA---QDTWGTSAAAYFVGY 243 (285)
3217 T ss_pred EEEEEEeeCCeEEEEEecCCCcccccCCCccccceeeEeeeeecccccccCCC---CCCCCC---CcccceeeEEEEEEe
3218 Confidence 99999999999999999888887999999999999999999999999997766 777776 678889999999999
3219
3220
3221 Q sp|P0DTC2|SPIK 270 LQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFT 307 (1273)
3222 Q Consensus 270 lqprtfllkynengtitdavdcaldplsetkctlksft 307 (1273)
3223 |.||+|||+|++||+|++||||+-||++|-||..||-.
3224 T Consensus 244 L~~~t~Ll~fd~nG~It~AvDCa~~~~sELkCs~~~~~ 281 (285)
3225 T 5X4S_A 244 LKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSHH 281 (285)
3226 T ss_pred cceeeEEEeecCCCeEeeEEEcccCcchhceeeecCCC
3227 Confidence 99999999999999999999999999999999998753
3228
3229
3230 No 31
3231 >5KWB_A Spike glycoprotein; Coronavirus spike protein, S1-CTD, receptor; HET: NAG, SUC; 1.91A {Human coronavirus HKU1 (isolate N1)}
3232 Probab=99.95 E-value=1.2e-33 Score=297.87 Aligned_cols=271 Identities=23% Similarity=0.387 Sum_probs=226.6 Template_Neff=3.700
3233
3234 Q sp|P0DTC2|SPIK 316 SNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNV 395 (1273)
3235 Q Consensus 316 snfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnv 395 (1273)
3236 |+|||||...++|.+.....|+|.++++|.+..+++.|.||.++||..|+|+|++......|+|||++|.||.+.||..|
3237 T Consensus 1 S~y~vqP~g~V~r~~~~~~~C~~~~~l~~~~~Psp~nWeR~~fsNCnfNls~Lls~v~~~sf~C~~i~pskl~~mCfsSv 80 (371)
3238 T 5KWB_A 1 SGFTVKPVATVHRRIPDLPDCDIDKWLNNFNVPSPLNWERKIFSNCNFNLSTLLRLVHTDSFSCNNFDESKIYGSCFKSI 80 (371)
3239 T ss_dssp ----CCCCCSEEECCTTCCBCCHHHHHTCSEEECGGGCEEEEECSEEECHHHHHHHTEEEEEEEESSCGGGTTTCEESEE
3240 T ss_pred CCceeeeeeEEEEeCCCCCCCCHHHHHhCCCCCCccccEEeEEecCCCCHHHHHhhceeceeeeeCCCHHHhcccccCee
3241 Confidence 68999999999999999999999999999999999999999999999999999999999999999999999999999999
3242
3243
3244 Q sp|P0DTC2|SPIK 396 YADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGG----NYNYLYRLFRKSNLKPFERDISTE 471 (1273)
3245 Q Consensus 396 yadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvgg----nynylyrlfrksnlkpferdiste 471 (1273)
3246 +.|.|.|..+..+++++|.+|-|++||||+|++|++|+++|+-..++..+.+ +|| |.++..+ |+......
3247 T Consensus 81 tiD~Faip~s~~~dLq~g~sG~i~~~NYKid~~~~sC~l~y~~~~~nvt~t~~nps~~n---~ry~~~~---f~~~~hdv 154 (371)
3248 T 5KWB_A 81 VLDKFAIPNSRRSDLQLGSSGFLQSSNYKIDTTSSSCQLYYSLPAINVTINNYNPSSWN---RRYGFNN---FNLSSHSV 154 (371)
3249 T ss_dssp EEEEEECCGGGGGGGSTTCCSHHHHHTCCCCSSSCEEEEEEEEEGGGCEEECCCCCHHH---HHTTCCC---CCCCTTEE
3250 T ss_pred EEEEEecCcccchhccCCCCcHhHhccccCCCCCCceEEEEEcccceeeecCCCcccch---hhccccC---cCccccce
3251 Confidence 9999999999999999999999999999999999999999997665555443 454 2223222 55555555
3252
3253
3254 Q sp|P0DTC2|SPIK 472 IYQ-----AGSTPCN---------------------------------------------GVEGFNCYFPLQSYGFQPTN 501 (1273)
3255 Q Consensus 472 iyq-----agstpcn---------------------------------------------gvegfncyfplqsygfqptn 501 (1273)
3256 +|. ++.+-|. +..++.|+-+...+.....-
3257 T Consensus 155 vYs~~cf~~~~~yCPC~~p~~~~~c~~~~~~~~~~~~~t~~r~c~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~q~~~~~ 234 (371)
3258 T 5KWB_A 155 VYSRYCFSVNNTFCPCAKPSFASSCKSHKPPSASCPIGTNYRSCESTTVLDHTDWCRCSCLPDPITAYDPRSCSQKKSLV 234 (371)
3259 T ss_dssp EEESCCEECCTTCCCSBCHHHHTTCCBSCCCBCBCCTTCCCCCEEEEEETTEEEEEEESSCSCTTTCSCGGGCSSEECCC
3260 T ss_pred eeeeeeeecCCCccCCCCccccccccCCCCCCCCCCCCccccccccccccccccccccccCCCCCcccCCCCccCceeee
3261 Confidence 554 2222221 11234455454444445567
3262
3263
3264 Q sp|P0DTC2|SPIK 502 GVGYQPYRVVVLSFEL-----------------------------------------LHAPATVCGP---KKSTNLVKNK 537 (1273)
3265 Q Consensus 502 gvgyqpyrvvvlsfel-----------------------------------------lhapatvcgp---kkstnlvknk 537 (1273)
3266 |+|++.+.+.|++.+. .-.++|+|.. +..++++.++
3267 T Consensus 235 gvg~~c~gl~v~~~kcg~~~~~~~~~C~C~~~af~gws~dsc~~~~~c~~f~n~~~~~~~T~t~cP~~~~~~~s~I~l~~ 314 (371)
3268 T 5KWB_A 235 GVGEHCAGFGVDEEKCGVLDGSYNVSCLCSTDAFLGWSYDTCVSNNRCNIFSNFILNGINSGTTCSNDLLQPNTEVFTDV 314 (371)
3269 T ss_dssp CTTCCCCCCCBCGGGBSBTTCCTTSBCCBCGGGBCSEEEEECEETTEEEEEEEEEEESTTCSSEEECSSCCCCCCCCCSS
3270 T ss_pred ccccccceEEEeeeeccCCCCCCCcccccCCCccccccccccccCCceeeccceeccCCCCCCcCCCcccCCCceEEeCe
3271 Confidence 9999999999999998 5668999998 6779999999
3272
3273
3274 Q sp|P0DTC2|SPIK 538 CVNFNFNGLTGTGVLTE-SNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSF 592 (1273)
3275 Q Consensus 538 cvnfnfngltgtgvlte-snkkflpfqqfgrdiadttdavrdpqtleilditpcsf 592 (1273)
3276 ||++|..|.+|+|++++ +++.++..|.+..+.+.-..+++++.++++..|+||..
3277 T Consensus 315 CVdYnIYG~tGqGvItnvT~~~~l~~~gL~yS~sgdl~~fk~~~tg~~Y~V~PC~~ 370 (371)
3278 T 5KWB_A 315 CVDYDLYGITGQGIFKEVSAVYYNSWQNLLYDSNGNIIGFKDFVTNKTYNIFPCYA 370 (371)
3279 T ss_dssp EEEEEETTEEEEEEEEEECGGGCCCSSSEEECTTSCEEEEECTTTCCEEEEECC--
3280 T ss_pred eeeEEeCCCeeeEEEEeccCceeecCCcEEEcCCCCEEEEEcCCCCcEEEEeeccc
3281 Confidence 99999999999999999 99889999999999999999999999999999999975
3282
3283
3284 No 32
3285 >6LXT_F Spike protein S2; 2019-nCoV, HR1 and HR2 domain; HET: PG4; 2.9A {Severe acute respiratory syndrome coronavirus 2}
3286 Probab=99.90 E-value=2.8e-28 Score=230.50 Aligned_cols=112 Identities=72% Similarity=0.855 Sum_probs=97.2 Template_Neff=2.500
3287
3288 Q sp|P0DTC2|SPIK 910 GVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEA 989 (1273)
3289 Q Consensus 910 gvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkvea 989 (1273)
3290 |+|++||.||||+||+.||.|++.|++.++++++||.|+|||||++++||+.|++||+.|||||||.++||.+|||++||
3291 T Consensus 1 gltt~VLq~NQk~iAnsFN~AignI~~gf~tts~AL~KIQdVVN~q~~aL~~Lt~QL~~NFgAISSSI~DIy~RLD~leA 80 (132)
3292 T 6LXT_F 1 GVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVES 80 (132)
3293 T ss_dssp ---CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC-
3294 T ss_pred CCchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHc
3295 Confidence 68999999999999999999999999999999999999999999999999999999999999999999999999999999
3296
3297
3298 Q sp|P0DTC2|SPIK 990 EVQID-RLITGRLQSLQTYVTQQLIRAAEIRAS 1021 (1273)
3299 Q Consensus 990 evqid-rlitgrlqslqtyvtqqliraaeiras 1021 (1273)
3300 ..|+| |||||||.+|..||+|.+.+.++...-
3301 T Consensus 81 daQvD~RLItGRLaaLna~v~q~~~~~~~~~~~ 113 (132)
3302 T 6LXT_F 81 GGRGGPDVDLGDISGINASVVNIQKEIDRLNEV 113 (132)
3303 T ss_dssp ---------CCCCTTCCCCCCCCHHHHHHHHHH
3304 T ss_pred cccCCcchhcccHHHHHHHHHHHHHHHHHHHHH
3305 Confidence 99999 799999999999999999998887543
3306
3307
3308 No 33
3309 >6LXT_C 2019-nCoV S2 subunit; 2019-nCoV, HR1 and HR2 domain; HET: PG4; 2.9A {COVID-19 virus}
3310 Probab=99.90 E-value=2.8e-28 Score=230.50 Aligned_cols=112 Identities=72% Similarity=0.855 Sum_probs=100.9 Template_Neff=2.500
3311
3312 Q sp|P0DTC2|SPIK 910 GVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEA 989 (1273)
3313 Q Consensus 910 gvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkvea 989 (1273)
3314 |+|++||.||||+||+.||.|++.|++.++++++||.|+|||||++++||+.|++||+.|||||||.++||.+|||++||
3315 T Consensus 1 gltt~VLq~NQk~iAnsFN~AignI~~gf~tts~AL~KIQdVVN~q~~aL~~Lt~QL~~NFgAISSSI~DIy~RLD~leA 80 (132)
3316 T 6LXT_C 1 GVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVES 80 (132)
3317 T ss_dssp --CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC-
3318 T ss_pred CCchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHc
3319 Confidence 68999999999999999999999999999999999999999999999999999999999999999999999999999999
3320
3321
3322 Q sp|P0DTC2|SPIK 990 EVQID-RLITGRLQSLQTYVTQQLIRAAEIRAS 1021 (1273)
3323 Q Consensus 990 evqid-rlitgrlqslqtyvtqqliraaeiras 1021 (1273)
3324 ..|+| |||||||.+|..||+|.+.+.++...-
3325 T Consensus 81 daQvD~RLItGRLaaLna~v~q~~~~~~~~~~~ 113 (132)
3326 T 6LXT_C 81 GGRGGPDVDLGDISGINASVVNIQKEIDRLNEV 113 (132)
3327 T ss_dssp ------CCCCCCCTTCCCCCCCCHHHHHHHHHH
3328 T ss_pred cccCCcchhcccHHHHHHHHHHHHHHHHHHHHH
3329 Confidence 99999 799999999999999999998887543
3330
3331
3332 No 34
3333 >6C6Z_A Spike protein, CDC2-C2 heavy chain; immune system, antibody, fusion glycoprotein; HET: NAG; 2.1A {Middle East respiratory syndrome-related coronavirus}
3334 Probab=99.85 E-value=6.9e-26 Score=228.84 Aligned_cols=148 Identities=22% Similarity=0.358 Sum_probs=108.8 Template_Neff=3.300
3335
3336 Q sp|P0DTC2|SPIK 319 RVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYAD 398 (1273)
3337 Q Consensus 319 rvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyad 398 (1273)
3338 |+||...++|+++. ..|+|.++++ .++.++|.|.|+.++||..|+++|++...+++|+||||+|.||.++||..|++|
3339 T Consensus 1 rAqP~g~V~r~~~~-~~C~~~~~l~-~~~Psp~nWeR~~fsNCnfNlS~Lls~v~v~sF~C~gIsPskLa~mCfsSVtiD 78 (231)
3340 T 6C6Z_A 1 EAKPSGSVVEQAEG-VECDFSPLLS-GTPPQVYNFKRLVFTNCNYNLTKLLSLFSVNDFTCSQISPAAIASNCYSSLILD 78 (231)
3341 T ss_dssp ---------------CBCCCHHHHS-BCCCBGGGCEEEEECSSBCCHHHHHTTSEEEEEEEC-----------CCEEEEE
3342 T ss_pred CccceeEEEEecCC-CCCCchHHhc-CCCCCcceeEEEEEecCCccHHHHHhcceeeeeeecCCCHHHHhhhccceeeEE
3343 Confidence 68999999999999 9999999999 999999999999999999999999999999999999999999999999999999
3344
3345
3346 Q sp|P0DTC2|SPIK 399 SFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEI 472 (1273)
3347 Q Consensus 399 sfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdistei 472 (1273)
3348 .|.|..++.++++||++|-|++||||+|+||+||+++|+-.+++..+.++.+|-|+..|. +|..|-++|.
3349 T Consensus 79 ~FaIp~s~~~~Lq~G~sG~i~~yNYKlp~~f~gC~l~y~~~~~~vnvt~p~~y~yia~r~----~~~~~~~~~~ 148 (231)
3350 T 6C6Z_A 79 YFSYPLSMKSDLSVSSAGPISQFNYKQSFSNPTCLILATVPHNLTTITKPLKYSYINKCS----RFLSDDRTEV 148 (231)
3351 T ss_dssp EEECCGGGGGGSSSSCCSHCCCCCCCCCSSSCEEEEEEECCTTCTTBCCCSEEEEEEEEE----EECTTSSCEE
3352 T ss_pred EEecChhhhhhccCCCCCchhhccccCCCCCCceEEEEEcCccccccCCCccceeeeeee----ccCCCCceEE
3353 Confidence 999999999999999999999999999999999999999777666555566666655544 3334445554
3354
3355
3356 No 35
3357 >5XGR_H Spike protein S1; MERS-CoV, BatCoV HKU5, CTD, evolution; HET: NAG; 2.1A {Bat coronavirus HKU5}
3358 Probab=99.85 E-value=9.7e-26 Score=224.72 Aligned_cols=181 Identities=21% Similarity=0.336 Sum_probs=148.3 Template_Neff=4.000
3359
3360 Q sp|P0DTC2|SPIK 335 LCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQ 414 (1273)
3361 Q Consensus 335 lcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgq 414 (1273)
3362 .|+|.++++ .++.++|.|.|+.++||..|+++|++..++++|+||||+|.||.+.||..|++|.|.|..+..++++||+
3363 T Consensus 2 ~C~~~~~l~-~~~Psp~nWeR~~fsNCnfNls~Lls~v~v~sF~C~~IspskLa~mCfsSvtiD~Faip~s~~~dLq~G~ 80 (204)
3364 T 5XGR_H 2 ECDFTPMLT-GTPPPIYNFKRLVFTNCNYNLTKLLSLFQVSEFSCHQVSPSSLATGCYSSLTVDYFAYSTDMSSYLQPGS 80 (204)
3365 T ss_dssp BCCCGGGGS-BCCCCGGGCEEEEECSEEECHHHHHTTSEEEEEEEESCCHHHHSSCCBSEEEEEEEECCGGGGGGGSTTC
3366 T ss_pred CCCChhHhc-CCCCCccceeEEEEecCCCCHHHHHhhceeeeeEeeCCCHHHhcccccceeEEEEEEecCccchhcCCCC
3367 Confidence 599999999 9999999999999999999999999999999999999999999999999999999999999999999999
3368
3369
3370 Q sp|P0DTC2|SPIK 415 TGKIADYNYKLPDDFTGCVIAWNSNNLDSK--VGGNYNYLYRLFRKSN-----LKPFERDISTEIYQAGSTPCNGVEGFN 487 (1273)
3371 Q Consensus 415 tgkiadynyklpddftgcviawnsnnldsk--vggnynylyrlfrksn-----lkpferdisteiyqagstpcngvegfn 487 (1273)
3372 +|-|++||||+|++|+||+++|+-...+.. --++|+|+-|..+++. +.++++|++. |-... -+
3373 T Consensus 81 sG~i~~yNYKld~s~~sC~l~~~~p~~~vnvt~ps~y~y~~~r~~~~~~~~~~~~~~~~~~cp---------c~~~~-~~ 150 (204)
3374 T 5XGR_H 81 AGAIVQFNYKQDFSNPTCRVLATVPQNLTTITKPSNYAYLTECYKTSAYGKNYLYNAPGAYTP---------CLSLA-SR 150 (204)
3375 T ss_dssp CSHHHHHTCCCCTTSCEEEEEEECCTTCCSBCCCSEEEEEEEEEEECSSSEEECCCCTTCCCT---------THHHH-TT
3376 T ss_pred CchhHhcccCCCCCCCccEEEEEcCchhcccCCccchheeeceeccccccccceeeCCCCccc---------ccccc-cC
3377 Confidence 999999999999999999999995543321 2567777777777665 5555555543 11000 23
3378
3379
3380 Q sp|P0DTC2|SPIK 488 CYF---PLQS----YGFQ--PTNGVGYQPYRVVVLSFELLHAPATVCGPK 528 (1273)
3381 Q Consensus 488 cyf---plqs----ygfq--ptngvgyqpyrvvvlsfellhapatvcgpk 528 (1273)
3382 |+- |+.. +++| ...|+|+| +++|++++....+-|||.-.
3383 T Consensus 151 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~--g~~Vis~k~g~~~~~~~~~~ 198 (204)
3384 T 5XGR_H 151 GFSTKYQSHSDGELTTTGYIYPVTGNLQ--MAFIISVQYGTDTNSVCPMQ 198 (204)
3385 T ss_dssp CCSSTTCEEECSSEEEEEEEEECCSSCE--EEEEEEEECCSCTTSEEECC
3386 T ss_pred CcccCccccCCCcccccCeEeeecCccc--EEEEEEEEeCCCCCcccccc
3387 Confidence 333 3222 4453 24588888 99999999999999999643
3388
3389
3390 No 36
3391 >4QZV_B Dipeptidyl peptidase 4 (E.C.3.4.14.5), Spike; 8-BLADED BETA-PROPELLER DOMAIN, ALPHA/BETA HYDROLASE; HET: NAG, BMA; 2.592A {Homo sapiens}
3392 Probab=99.83 E-value=4.1e-25 Score=224.70 Aligned_cols=137 Identities=24% Similarity=0.439 Sum_probs=111.3 Template_Neff=3.300
3393
3394 Q sp|P0DTC2|SPIK 319 RVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYAD 398 (1273)
3395 Q Consensus 319 rvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyad 398 (1273)
3396 .+||...++|+++. ..|+|.++|+ .++.++|.|.|+.++||..|+++|++...+++|+||||||.||.++||..|++|
3397 T Consensus 1 ~AqP~g~V~r~~~~-~~C~~~~~l~-~~~Psp~nWeR~~fsNCnfN~S~Lls~v~v~sF~C~gIsPskLa~mCfsSVtiD 78 (246)
3398 T 4QZV_B 1 EASATGTFIEQPNA-TECDFSPMLT-GVAPQVYNFKRLVFSNCNYNLTKLLSLFAVDEFSCNGISPDSIARGCYSTLTVD 78 (246)
3399 T ss_dssp ---------------CBCCCCTTTS-SCCCCGGGCEEEEECSCBBCHHHHHTTEEEEEEEEESSCTTGGGTCCBSEEEEE
3400 T ss_pred CceeeeEEEEcCCC-CCCCChHHhc-CCCCCcceeEEEEEecCCCcHHHHHhhceeeeeEecCCCHHHHcccccceeeEE
3401 Confidence 37899999999999 9999999999 999999999999999999999999999999999999999999999999999999
3402
3403
3404 Q sp|P0DTC2|SPIK 399 SFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKV--GGNYNYLYRLFRK 458 (1273)
3405 Q Consensus 399 sfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskv--ggnynylyrlfrk 458 (1273)
3406 .|.|..+..++++||++|-|++||||||+||+||+++|+-.+ +..+ -++|+|+.|..++
3407 T Consensus 79 ~FaIp~s~~~~Lq~G~sG~i~~yNYKlp~~f~gC~l~y~~~~-nvn~t~p~~y~yia~r~~~ 139 (246)
3408 T 4QZV_B 79 YFAYPLSMKSYIRPGSAGNIPLYNYKQSFANPTCRVMASVLA-NVTITKPHAYGYISKCSRL 139 (246)
3409 T ss_dssp EEECCGGGGGGGSTTCCCHCCCCCCCCCCSSCEEEEEEEECT-TSCCCCCSEEEEEEEEEEE
3410 T ss_pred EEEcchhhhhhcCCCCCCchhhccccCCCCCCceEEEEEecc-ccccCCcccceeeeeeecC
3411 Confidence 999999999999999999999999999999999999999555 2222 3455555554433
3412
3413
3414 No 37
3415 >4L3N_B S protein; beta-sheet fold, VIRAL PROTEIN; HET: NAG; 2.13A {Human betacoronavirus 2c Jordan-N3/2012}
3416 Probab=99.81 E-value=2.3e-24 Score=216.33 Aligned_cols=124 Identities=20% Similarity=0.356 Sum_probs=116.1 Template_Neff=3.200
3417
3418 Q sp|P0DTC2|SPIK 334 NLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPG 413 (1273)
3419 Q Consensus 334 nlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapg 413 (1273)
3420 ..|+|.++++ .++.++|.|.|+.++||..|+++|++...+++|+||||||+||.++||..|++|.|.|..+++++++||
3421 T Consensus 3 ~~C~~~~~l~-~~~PsP~nWeR~~fsNCnfNlS~Lls~v~v~sF~C~gIsPskLa~mCfsSVtiD~FaIp~s~~~~Lq~G 81 (216)
3422 T 4L3N_B 3 VECDFSPLLS-GTPPQVYNFKRLVFTNCNYNLTKLLSLFSVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVS 81 (216)
3423 T ss_dssp CBCCCGGGGS-BCCCCGGGCEEEEECSEEECHHHHHHTSEEEEEEEESSCHHHHTTCCBSEEEEEEEECCGGGHHHHHTG
3424 T ss_pred CCCCchHHhc-CCCCCcceeEEEEEecCCccHHHHHhcceeeeeeecCCCHHHHhhhccceeeEEEEecChhhhhhccCC
3425 Confidence 5799999999 999999999999999999999999999999999999999999999999999999999999999999999
3426
3427
3428 Q sp|P0DTC2|SPIK 414 QTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRK 458 (1273)
3429 Q Consensus 414 qtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrk 458 (1273)
3430 ++|-|++||||+|+||+||+++|+-.+++..+.++.+|-|+..|.
3431 T Consensus 82 ssG~i~~yNYKlp~df~gC~l~y~~~~~~vnvt~p~~y~yia~r~ 126 (216)
3432 T 4L3N_B 82 SAGPISQFNYKQSFSNPTCLILATVPHNLTTITKPLKYSYINKCS 126 (216)
3433 T ss_dssp GGSHCCCCCCCCCSSSCEEEEEEECCTTCCSBCCCSEEEEEEEEE
3434 T ss_pred CCCchhhccccCCCCCCccEEEEEcCccccccCCCcccceeeeee
3435 Confidence 999999999999999999999999877766666677777666555
3436
3437
3438 No 38
3439 >5YY5_B MERS-CoV RBD, Heavy chain, Light; MERS-CoV, spike glycorptotein, neutralizing antibody; HET: NAG; 2.8A {Middle East respiratory syndrome coronavirus}
3440 Probab=99.81 E-value=3.5e-24 Score=214.39 Aligned_cols=124 Identities=20% Similarity=0.356 Sum_probs=115.2 Template_Neff=3.300
3441
3442 Q sp|P0DTC2|SPIK 334 NLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPG 413 (1273)
3443 Q Consensus 334 nlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapg 413 (1273)
3444 ..|+|.++++ .++.++|.|.|+.++||..|+++|++...+++|+||||+|.||.++||..|++|.|.|..+++++++||
3445 T Consensus 2 ~~C~~~~~l~-~~~Psp~nWeR~~fsNCnfNlS~Lls~v~v~sF~C~gIsPskLa~mCfsSVtiD~FaIp~s~~~~Lq~G 80 (209)
3446 T 5YY5_B 2 VECDFSPLLS-GTPPQVYNFKRLVFTNCNYNLTKLLSLFSVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVS 80 (209)
3447 T ss_dssp CBCCCGGGGS-BCCCBGGGCEEEEECSEEECHHHHHHTSEEEEEEEESSCHHHHTTCCBSEEEEEEEECCGGGGGGSSTT
3448 T ss_pred CCCCchHHhc-CCCCCcceeEEEEEecCCccHHHHHhcceeeeeeecCCCHHHHhhhccceeeEEEEecChhhhhhccCC
3449 Confidence 4799999999 999999999999999999999999999999999999999999999999999999999999999999999
3450
3451
3452 Q sp|P0DTC2|SPIK 414 QTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRK 458 (1273)
3453 Q Consensus 414 qtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrk 458 (1273)
3454 ++|-|++||||+|+||+||+++|+-.+++..+.++.+|-|+..|.
3455 T Consensus 81 ~sG~i~~yNYKlp~~f~gC~l~y~~~~~~vnvt~p~~y~yia~r~ 125 (209)
3456 T 5YY5_B 81 SAGPISQFNYKQSFSNPTCLILATVPHNLTTITKPLKYSYINKCS 125 (209)
3457 T ss_dssp CCSHCCCCCCCCCSSSCEEEEEEECCTTCTTBCCCSCEEEEEEEE
3458 T ss_pred CCCchhhccccCCCCCCccEEEEEcCccccccCCCcccceeeeee
3459 Confidence 999999999999999999999999777666655666666665554
3460
3461
3462 No 39
3463 >4L72_B Dipeptidyl peptidase 4 (E.C.3.4.14.5), MERS-CoV; alpha/beta hydrolase beta-propeller, Glycolation, virus; HET: BMA, NAG; 3.005A {Homo sapiens}
3464 Probab=99.81 E-value=4e-24 Score=213.42 Aligned_cols=123 Identities=20% Similarity=0.365 Sum_probs=115.1 Template_Neff=3.300
3465
3466 Q sp|P0DTC2|SPIK 335 LCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQ 414 (1273)
3467 Q Consensus 335 lcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgq 414 (1273)
3468 .|+|.++++ .++.++|.|.|+.++||..|+++|++...+++|+||||+|+||.++||..|++|.|.|..+++++++||+
3469 T Consensus 1 ~C~~~~~~~-~~~Psp~nWeR~~fsNCnfNlS~Lls~v~v~sF~C~gIsPskLa~mCfsSVtiD~FaIp~s~~~~Lq~G~ 79 (204)
3470 T 4L72_B 1 ECDFSPLLS-GTPPQVYNFKRLVFTNCNYNLTKLLSLFSVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVSS 79 (204)
3471 T ss_pred CCChhHHhh-cCCCCcceeEEEEEecCCCCHHHHHhhceeeeeEeeCCCHHHHcccccCeeeEEEEeccccchhhcCCCC
3472 Confidence 489999999 9999999999999999999999999999999999999999999999999999999999999999999999
3473
3474
3475 Q sp|P0DTC2|SPIK 415 TGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRK 458 (1273)
3476 Q Consensus 415 tgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrk 458 (1273)
3477 +|-|++||||+|+||+||+++|+-.+++..+.++.+|-|+..|.
3478 T Consensus 80 sG~i~~yNYKlp~~f~gC~l~y~~~~~~vnvt~p~~y~yia~r~ 123 (204)
3479 T 4L72_B 80 AGPISQFNYKQSFSNPTCLILATVPHNLTTITKPLKYSYINKCS 123 (204)
3480 T ss_pred CchHHhccccCCCCCCceEEEEEcCcccccCCCccccceeeeec
3481 Confidence 99999999999999999999999877666666677777666555
3482
3483
3484 No 40
3485 >3R4D_D CEA-related cell adhesion molecule 1; immunoglobulin, beta-sandwich, mCEACAM1a - immunoglobulin; HET: NAG; 3.1A {Mus musculus}
3486 Probab=99.80 E-value=5.2e-24 Score=219.92 Aligned_cols=240 Identities=20% Similarity=0.268 Sum_probs=141.9 Template_Neff=4.700
3487
3488 Q sp|P0DTC2|SPIK 30 NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG---TKRFDNPVLPFNDGVYFASTEKSNI------ 100 (1273)
3489 Q Consensus 30 nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng---tkrfdnpvlpfndgvyfasteksni------ 100 (1273)
3490 -|-.+|+||||..++|++.+-.|+||.++-++.+-.-. +|++- --.+++++.||+||+++...+++|.
3491 T Consensus 30 vs~~~G~yYp~~rvysN~t~L~qglfp~~gs~~~~y~~---t~~~~~~~~~~y~~~~~~F~dGifv~v~~~~n~~~~~~~ 106 (288)
3492 T 3R4D_D 30 VSQGLGTYYVLDRVYLNATLLLTGYYPVDGSKFRNLAL---TGTNSVSLSWFQPPYLSQFNDGIFAKVQNLKTSTPSGAT 106 (288)
3493 T ss_dssp ---------------------CEEECCCTTCCCEECCC---EESSEEEGGGSSTTTSEECTTEEEEEEECGGGGSCTTCC
3494 T ss_pred eecCeEEEEeCCeEEeceeeeecccccCCCCceEEEEe---ecCCCCccceecCCcchhcCCeEEEEeeecccCCCCccc
3495 Confidence 45578999999999999999999999999988875422 34332 2467888999999999999998875
3496
3497
3498 Q sp|P0DTC2|SPIK 101 --IRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMD 178 (1273)
3499 Q Consensus 101 --irgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmd 178 (1273)
3500 -..++||+|.+..+++++|+++-+...|.+|.|+.|..|.+.++..-+|.+.. +++. ..+.||+|.+. +.|-+|
3501 T Consensus 107 ~~ypa~~fGstf~n~s~tvvI~P~~~~~~it~C~~~vC~~p~~~~~p~~g~~~~~--~~~~-~~~~~c~~~~~-~nfT~d 182 (288)
3502 T 3R4D_D 107 AYFPTIVIGSLFGYTSYTVVIEPYNGVIMASVCQYTICQLPYTDCKPNTNGNKLI--GFWH-TDVKPPICVLK-RNFTLN 182 (288)
3503 T ss_dssp CCSCCEEEESSCSSSSEEEEEEEETTEEEEEEEECCBBSSCCEESSCCCTTCTTC--CSSB-CCSSCCCEEEE-EEEECC
3504 T ss_pred eecceEEEecccCCcceEEEEeCCCceEEEEEEEEEEcCCCeeEEccCCCCCcee--eeee-ecCCCCEEEEe-eeeccC
3505 Confidence 46788999999999999999999999999999999999999888744332222 3445 67889999764 445444
3506
3507
3508 Q sp|P0DTC2|SPIK 179 LEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINL---VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSS 255 (1273)
3509 Q Consensus 179 legkqgnfknlrefvfknidgyfkiyskhtpinl---vrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdss 255 (1273)
3510 ...+ .|. |+|++.||.|-+|-.+...+. .+.+| |+..+.+. .+-|+..++ +
3511 T Consensus 183 ~~~~--~~~----f~F~~~~G~f~~Y~~~~~~~~~f~f~~~~-g~~~~~yy----------------vip~~~~~~---~ 236 (288)
3512 T 3R4D_D 183 VNAD--AFY----FHFYQHGGTFYAYYADKPSATTFLFSVYI-GDILTQYY----------------VLPFICNPT---A 236 (288)
3513 T ss_dssp TTCS--EEE----EEEEEETTEEEEEEESSSSCCEEEEEEEC-SSCCCEEE----------------ECCEECCCS---S
3514 T ss_pred cChh--eee----EEEEEcCCEEEEEEECCCCCceeeeccee-ccccceeE----------------EeeeeecCC---C
3515 Confidence 3321 122 999999999988877766553 55555 66555555 334444444 4
3516
3517
3518 Q sp|P0DTC2|SPIK 256 SGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLK 304 (1273)
3519 Q Consensus 256 sgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlk 304 (1273)
3520 ++| ..++|||++|.+|+|||+|++||.|++||||+-|+++|-||...
3521 T Consensus 237 ~~~--~~~~~yV~~L~~r~yLl~Fd~nG~It~AvDCa~~~~sEL~~~~~ 283 (288)
3522 T 3R4D_D 237 GST--FAPRYWVTPLVKRQYLFNFNQKGVITSAVDCASSYTSEIKCKTH 283 (288)
3523 T ss_dssp CSC--CCCCEEEEECCEEEC-----------------------------
3524 T ss_pred CCc--cccEEEEEeceeeeEEEeecCCCeEeEEEEcccCcccccccccC
3525 Confidence 455 78899999999999999999999999999999999999999743
3526
3527
3528 No 41
3529 >4NJL_A S protein; six-helix-bundle, coronavirus, MERS-Cov, fusion inhibitor; HET: PGE; 2.3A {Middle East respiratory syndrome coronavirus}
3530 Probab=99.79 E-value=1.2e-23 Score=199.38 Aligned_cols=122 Identities=42% Similarity=0.571 Sum_probs=111.0 Template_Neff=2.500
3531
3532 Q sp|P0DTC2|SPIK 910 GVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEA 989 (1273)
3533 Q Consensus 910 gvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkvea 989 (1273)
3534 |+||+||.||||+||+.||.|+|.|++.+.++++||.|+|||||++++||+.|+.||+.|||||||.++||.+|||++||
3535 T Consensus 2 gltq~VLq~NQk~iA~sFN~AignIq~gf~tts~AL~KIQdVVN~q~~aL~~Lt~QL~nNFgAISSSIqdIy~RLD~LeA 81 (131)
3536 T 4NJL_A 2 GITQQVLSENQKLIANKFNQALGAMQTGFTTTNEAFQKVQDAVNNNAQALSKLASELSNTFGAISASIGDIIQRLDVLEQ 81 (131)
3537 T ss_dssp -CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
3538 T ss_pred CcchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHh
3539 Confidence 78999999999999999999999999999999999999999999999999999999999999999999999999999999
3540
3541
3542 Q sp|P0DTC2|SPIK 990 EVQIDRLI--TGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLG 1035 (1273)
3543 Q Consensus 990 evqidrli--tgrlqslqtyvtqqliraaeirasanlaatkmsecvlg 1035 (1273)
3544 .+|++|+| .||++-+.+ +|....-+..|+.-+..|..||...
3545 T Consensus 82 Daqrl~~l~~~~~~~~~n~----~l~d~t~~~~s~~q~~~~~ne~~~~ 125 (131)
3546 T 4NJL_A 82 SGGRGGSIPNFGSLTQINT----TLLDLTYEMLSLQQVVKALNESYID 125 (131)
3547 T ss_dssp SSSCSCCCCCCCCCCCCCC----CCCCCHHHHHHHHHHHHHHHTTCCC
3548 T ss_pred HhcccchhhhhhhHHHHhH----hHHHHHHHHhhHHHHHHHHHHhccc
3549 Confidence 99999988 888776665 6666666777887788888888653
3550
3551
3552 No 42
3553 >6QFY_A Spike glycoprotein; sialic acid binding, beta-sandwich, viral; HET: NAG, BMA; 2.97A {Porcine hemagglutinating encephalomyelitis virus}
3554 Probab=99.78 E-value=2.6e-23 Score=214.69 Aligned_cols=236 Identities=20% Similarity=0.276 Sum_probs=176.2 Template_Neff=4.800
3555
3556 Q sp|P0DTC2|SPIK 30 NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG---TKRFDNPVLPFNDGVYFASTEKSNII----- 101 (1273)
3557 Q Consensus 30 nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng---tkrfdnpvlpfndgvyfasteksnii----- 101 (1273)
3558 -|-.+|+||||..++|+..+-.|+||.++-++.+-.-. +|++- --.+++++.||+||+++...+++|.-
3559 T Consensus 29 vs~~~G~yYp~~r~ysN~t~L~qglfp~~gs~~~~y~~---t~~~~~~~~~~y~~~~~~F~dGifv~v~~~~n~~~~~~~ 105 (288)
3560 T 6QFY_A 29 VTNGLGTFYVLDRVYLNTTLLLNGYYPISGATFRNMAL---KGTRLLSTLWFKSPFLSPFNDGIFAKVKNSRFSKDGVIY 105 (288)
3561 T ss_dssp CTTSTTCBCCTTCCCCSEEEEEEEEEECTTCEEEECCC---EESSCEEGGGGSTTTSEECSSEEEEEEECBCCEETTEEC
3562 T ss_pred cccCceeEecCCceeccceeeeeceecCCCCCceeeee---ecCCCCCcceecCCCcccccCcEEEEeEEeecCCCCCce
3563 Confidence 45568999999999999999999999999888875422 33332 34678889999999999999988863
3564
3565
3566 Q sp|P0DTC2|SPIK 102 ---RGWIFGTTLDSKTQSLLIVNNATNV-----V---IKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEY 170 (1273)
3567 Q Consensus 102 ---rgwifgttldsktqsllivnnatnv-----v---ikvcefqfcndpflgvyyhknnkswmesefrvyssannctfey 170 (1273)
3568 -.++||+|.+..+++++|+++-+++ . |.+|.|+.|..|...++..-.| + --+++. ..+.+|+|.+
3569 T Consensus 106 ~~yp~~~fGstf~n~s~tvvI~P~~~g~~~~~~~~~~it~C~~~vC~~p~~~~~p~~g~-~--~~~~~~-~~~~~c~~~~ 181 (288)
3570 T 6QFY_A 106 SEFPAITIGSTFVNSSHSIVVKPHTSFINGNLQGLLQISVCQYTMCEYPHTICHPNLGN-Q--RIELWH-YDTDVVSCLY 181 (288)
3571 T ss_dssp CBCCCEEEESSCSTTSCEEEEEEEE----EEEEEEEEEEEECCCEEEEEEEECCGGGCC-S--SCCEEE-CC----CSEE
3572 T ss_pred eecCceeeeccccCCceEEEEcCCCCCeeccccccceeeeeeEEecCCCeeEEcCCCCC-c--cceeeE-EecCCceEEE
3573 Confidence 3677999999999999999998864 3 6799999999999988874443 3 234555 7789999976
3574
3575
3576 Q sp|P0DTC2|SPIK 171 VSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINL---VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRS 247 (1273)
3577 Q Consensus 171 vsqpflmdlegkqgnfknlrefvfknidgyfkiyskhtpinl---vrdlpqgfsaleplvdlpiginitrfqtllalhrs 247 (1273)
3578 . +.|-+|...+ .|. |+|++.||.|-+|-.+...+. .+.+| |+..+.+. -+|..++
3579 T Consensus 182 ~-~nfT~d~~~~--~~~----f~F~~~~G~f~~Y~~~~~~~~~f~f~~~~-~~~~~~yy-vip~~~~------------- 239 (288)
3580 T 6QFY_A 182 K-RNFTYDVNAD--YLY----FHFYQEGGTFYAYFTDTGFVTKFLFKLYL-GTVLSHYY-VMPLTCD------------- 239 (288)
3581 T ss_dssp E-ECCBCCTTCS--EEE----EEEEEETTEEEEEEESSSSSBEEEEEEEC-SSCCCEEE-ECCEECS-------------
3582 T ss_pred e-eeeccccccc--eEE----EEEEEcCCeEEEEEeccCCcceeeecCCc-ccccceeE-EceecCC-------------
3583 Confidence 4 4554444332 222 999999999988877766553 55566 66666665 2232222
3584
3585
3586 Q sp|P0DTC2|SPIK 248 YLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKS 305 (1273)
3587 Q Consensus 248 yltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlks 305 (1273)
3588 ++ ..++|||++|.+|+|||+|++||.|++||||+-|+++|-||..+|
3589 T Consensus 240 --~~---------~~~~~yV~~L~~~~yLl~Fd~nG~It~AvDCa~~~~sEL~Cst~S 286 (288)
3590 T 6QFY_A 240 --SA---------LSLEYWVTPLTTRQFLLAFDQDGVLYHAVDCASDFMSEIMCKTSS 286 (288)
3591 T ss_dssp --S-------------CEEEEEEEEEEEEEEECTTCCEEEEEETTSCHHHHHHHHCCS
3592 T ss_pred --Cc---------cceeEEEEEcceeeEEEeecCCCeEeeEEEcccCcchhhccccCC
3593 Confidence 22 668999999999999999999999999999999999999998776
3594
3595
3596 No 43
3597 >4H14_A Spike glycoprotein; beta-sandwich, sugar binding, VIRAL PROTEIN; HET: NAG; 1.55A {Bovine coronavirus}
3598 Probab=99.78 E-value=3.5e-23 Score=214.01 Aligned_cols=235 Identities=21% Similarity=0.266 Sum_probs=184.1 Template_Neff=4.700
3599
3600 Q sp|P0DTC2|SPIK 30 NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG---TKRFDNPVLPFNDGVYFASTEKSNI------ 100 (1273)
3601 Q Consensus 30 nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng---tkrfdnpvlpfndgvyfasteksni------ 100 (1273)
3602 -|-.+|+||||..++|+..+-.|+||.++-++.+-.-. +|++- --.+++++.||+||+++...+++|.
3603 T Consensus 29 vs~~~G~yYp~~rvysN~t~L~qglfp~~gs~~~~y~~---t~~~~~~~~~~y~~~~~~F~dGifv~v~~~~n~~~~~~~ 105 (290)
3604 T 4H14_A 29 VTNGLGTYYVLDRVYLNTTLLLNGYYPTSGSTYRNMAL---KGTLLLSRLWFKPPFLSDFINGIFAKVKNTKVIKKGVMY 105 (290)
3605 T ss_dssp CTTSTTCBCCTTCCCCSEEEEEEEEECCTTCCCEECCC---EESSCEEGGGGSTTTSEECSSEEEEEEECEEEEETTEEE
3606 T ss_pred cccCeeEEEeCCeEEeeeeeeecceecCCCCceeeeee---eeccccccccccCCccccccCcEEEEEEeecccCCCcee
3607 Confidence 45578999999999999999999999999988875422 34332 2467888999999999999998875
3608
3609
3610 Q sp|P0DTC2|SPIK 101 --IRGWIFGTTLDSKTQSLLIVNNATNV-----V---IKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEY 170 (1273)
3611 Q Consensus 101 --irgwifgttldsktqsllivnnatnv-----v---ikvcefqfcndpflgvyyhknnkswmesefrvyssannctfey 170 (1273)
3612 -..++||+|.+..+++++|+++-+++ . |.+|.|+.|..|.+.++..-.| + --+++. ..+.||+|.|
3613 T Consensus 106 ~~ypa~~fGstf~n~s~tvvI~P~~~g~~~~~~~~~~it~C~~~vC~~p~~~~~p~~g~-~--~~~~~~-~~~~~c~~~~ 181 (290)
3614 T 4H14_A 106 SEFPAITIGSTFVNTSYSVVVQPHTTNLDNKLQGLLEISVCQYTMCEYPHTICHPKLGN-K--RVELWH-WDTGVVSCLY 181 (290)
3615 T ss_dssp EECCCEEEESSCSTTSCEEEEEEEEEESSSSEEEEEEEEEECCCEEEEEEEECCGGGCC-S--SCCEEE-CCCSCCCEEE
3616 T ss_pred eecCeeEEeccccCCeeEEEEcCCCCCccchhcceeEeeeeeEEecCCCeEEEeccCCC-c--eeeeeE-EecCCceEEE
3617 Confidence 46788999999999999999998864 3 6799999999999988874443 3 234455 7789999976
3618
3619
3620 Q sp|P0DTC2|SPIK 171 VSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINL---VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRS 247 (1273)
3621 Q Consensus 171 vsqpflmdlegkqgnfknlrefvfknidgyfkiyskhtpinl---vrdlpqgfsaleplvdlpiginitrfqtllalhrs 247 (1273)
3622 . +.|-+|...+ .|. |+|++.||.|-+|-.+...+. .+.+| |+..+.+. -+|..++.
3623 T Consensus 182 ~-~nfT~d~~~~--~~~----f~F~~~~G~f~~Y~~~~~~~~~f~f~~~~-~~~~~~yy-vip~~~~~------------ 240 (290)
3624 T 4H14_A 182 K-RNFTYDVNAD--YLY----FHFYQEGGTFYAYFTDTGVVTKFLFNVYL-GTVLSHYY-VLPLTCSS------------ 240 (290)
3625 T ss_dssp E-EEEECCTTCS--EEE----EEEEEETTEEEEEEESSSSSBEEEEEEEC-SSCCCEEE-ECCEECSS------------
3626 T ss_pred e-eeeccccccc--eee----EEEEEeCCeEEEEEEccCcccceEeccee-eeecceeE-EceeecCC------------
3627 Confidence 4 4554544332 222 999999999988877766553 55566 66666665 23333332
3628
3629
3630 Q sp|P0DTC2|SPIK 248 YLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLK 304 (1273)
3631 Q Consensus 248 yltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlk 304 (1273)
3632 + ..++|||++|.+|+|||+|++||.|++||||+-|+++|-||...
3633 T Consensus 241 ---~---------~~~~~yV~~L~~r~yLl~Fd~nG~It~AvDCa~~~~sEL~c~~~ 285 (290)
3634 T 4H14_A 241 ---A---------MTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKSDFMSEIKCKTH 285 (290)
3635 T ss_dssp ---C---------CCCCEEEEEEEEEEEEEEECTTSCEEEEEETTSSHHHHHHHHSC
3636 T ss_pred ---c---------cceeEEEEeceeeeEEEEecCCCeEeEEEecccCcchhhhcccC
3637 Confidence 1 66899999999999999999999999999999999999999753
3638
3639
3640 No 44
3641 >4MOD_B HR1 of S protein, LINKER; MERS-CoV, Viral envelope proteins, Spike; 1.901A {Human betacoronavirus 2c EMC/2012}
3642 Probab=99.75 E-value=1.9e-22 Score=191.27 Aligned_cols=118 Identities=35% Similarity=0.489 Sum_probs=66.4 Template_Neff=3.100
3643
3644 Q sp|P0DTC2|SPIK 918 ENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKV--EAEVQIDR 995 (1273)
3645 Q Consensus 918 enqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkv--eaevqidr 995 (1273)
3646 ||||+||+.||.|+|.|++.+.++++||.|+|||||+++++|+.|.+||..|||+|||.++||..|||++ ||.+|+||
3647 T Consensus 2 ~NQk~iA~sFN~A~~~i~~~~~t~~~Al~kiQ~VVN~q~~aL~~l~~EL~knFkAISSsI~dIy~rld~~~~~ad~qvdr 81 (129)
3648 T 4MOD_B 2 ENQKLIANKFNQALGAMQTGFTTTNEAFQKVQDAVNNNAQALSKLASELSNTFGAISASIGDILVPRGSGGSGGSGGLEV 81 (129)
3649 T ss_dssp -CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC--------------------------------
3650 T ss_pred hHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhCcchhhHHHhhhccCCCCCCccccchh
3651 Confidence 7999999999999999999999999999999999999999999999999999999999999999999997 89999999
3652
3653
3654 Q sp|P0DTC2|SPIK 996 LITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKR 1039 (1273)
3655 Q Consensus 996 litgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskr 1039 (1273)
3656 ||+|||.+|.++++.--...++++ -...+.-||+..+.+-
3657 T Consensus 82 LitgrL~~LNa~~~dl~~em~~l~----~vvk~LNes~idlkel 121 (129)
3658 T 4MOD_B 82 LFQGPLTQINTTLLDLTYEMLSLQ----QVVKALNESYIDLKEL 121 (129)
3659 T ss_dssp -------CCCCCCCCCHHHHHHHH----HHHHHHHTTCCC----
3660 T ss_pred hcCCChHHHHHHHHHHHHHHHHHH----HHHHHHHHHhhcHHHH
3661 Confidence 999999999999876544333333 3667788888766543
3662
3663
3664 No 45
3665 >5X4R_A S protein; MERS-CoV, spike, N-terminal domain, VIRAL; HET: NAG; 1.5A {Middle East respiratory syndrome coronavirus}
3666 Probab=99.71 E-value=2.2e-21 Score=204.51 Aligned_cols=263 Identities=21% Similarity=0.314 Sum_probs=191.1 Template_Neff=4.200
3667
3668 Q sp|P0DTC2|SPIK 14 QCVNL-TTRTQLPPAYT----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG--T-------KRF 79 (1273)
3669 Q Consensus 14 qcvnl-ttrtqlppayt----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng--t-------krf 79 (1273)
3670 .|... ....-+++.++ -+-.+|+||||..++++..+-.|+||.+.-++.+-.- ++|++. + -.+
3671 T Consensus 12 ~C~~~~~~~~~~~~~~~~~idvs~~~G~yYp~~rvysN~tlL~qglfp~~gs~~~~y~---~~~~~~~~~~~~~~~~~~y 88 (342)
3672 T 5X4R_A 12 ACIEVDIQQTFFDKTWPRPIDVSKADGIIYPQGRTYSNITITYQGLFPYQGDHGDMYV---YSAGHATGTTPQKLFVANY 88 (342)
3673 T ss_dssp BCCCEEECGGGGCCCCCCCCCGGGTTTCBCCTTSCCCSEEEEEEEEECCTTCCCEEEC---CEECCBCSSCBCSEEECSG
3674 T ss_pred ceEEeccCccccCCCCCcceecccCceeEeeCCeeEeeeeeeeeccccCCCCcceEEE---EEecCCCCCCCcceeeecC
3675 Confidence 36665 23333444555 3446899999999999999999999999988887543 333333 2 356
3676
3677
3678 Q sp|P0DTC2|SPIK 80 DNPVLPFNDGVYFASTEKSNIIRG-----------------WIFGTTLDSKT---Q------SLLIVNNATNVVI----- 128 (1273)
3679 Q Consensus 80 dnpvlpfndgvyfasteksniirg-----------------wifgttldskt---q------sllivnnatnvvi----- 128 (1273)
3680 +.+..||+||+++...+++|.-.+ ++||+|.+... + +++|+++-++.++
3681 T Consensus 89 ~~~~~~F~dGifvkv~~~~n~t~~~~~~~~~~~~~~~~ypa~~fGstF~N~s~~~~~~~~~~tlvI~P~~~g~~~~~~~c 168 (342)
3682 T 5X4R_A 89 SQDVKQFANGFVVRIGAAANSTGTVIISPSTSATIRKIYPAFMLGSSVGNFSDGKMGRFFNHTLVLLPDGCGTLLRAFYC 168 (342)
3683 T ss_dssp GGCCEECTTCEEEEESTTTTSEEECSSSTTCEEEEECCCCCEEEESCEEECTTSCEEEECSEEEEEEEETTTTEEEEEEE
3684 T ss_pred CCChhhccCeEEEEEeeeeccCCCeeecCccccchhhcccceEEecccccCCCccceeecceEEEEecCCCCceeeeEee
3685 Confidence 788999999999998887776443 57999999777 6 8999999888765
3686
3687
3688 Q sp|P0DTC2|SPIK 129 --KVCEFQFCNDPFLGVYYHKNN---KSWMES---------EFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVF 194 (1273)
3689 Q Consensus 129 --kvcefqfcndpflgvyyhknn---kswmes---------efrvyssannctfeyvsqpflmdlegkqgnfknlrefvf 194 (1273)
3690 ..++..-|..|..-+++--+. -+|+.+ +++.|..+.||+|.+. +.|-+|. +.+.|. |.|
3691 T Consensus 169 ~~~prtit~C~~p~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~f~~~~nc~f~~~-~nfT~d~--~~~wf~----~~F 241 (342)
3692 T 5X4R_A 169 ILEPRSGNHCPAGNSYTSFATYHTPATDCSDGNYNRNASLNSFKEYFNLRNCTFMYT-YNITEDE--ILEWFG----ITQ 241 (342)
3693 T ss_dssp EEEECCSBTSTTSTTCCCCCEEECHHHHSCTTCCCTTHHHHHHHHHEEEEEEEEEEE-EECCCCC--CCEEEE----EEE
3694 T ss_pred eeccCccccCCCCCeEeeeeecCCCCccCCCccccccccccchhhhcccCCcEEEEe-eecCcch--hhheEE----EEE
3695 Confidence 333344566666655542221 345444 6778899999999875 3444443 333444 999
3696
3697
3698 Q sp|P0DTC2|SPIK 195 KNID-GYFKIYSKHTPINL---VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYL 270 (1273)
3699 Q Consensus 195 knid-gyfkiyskhtpinl---vrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgyl 270 (1273)
3700 ++.| |.|-+|-.++..+. ...+| |...|.+..-+|..++ ++ .+.|. ..++|||++|
3701 T Consensus 242 ~~~~~G~f~~Y~~d~~~~~~f~f~~~p-g~~~l~yy~viprs~~---------------~~---~~~~~-~~~ayyV~~L 301 (342)
3702 T 5X4R_A 242 TAQGVHLFSSRYVDLYGGNMFQFATLP-VYDTIKYYSIIPHSIR---------------SI---QSDRK-AWAAFYVYKL 301 (342)
3703 T ss_dssp ETTEEEEEESTTTCTTTCCBEEEEEEC-CCSCCCEEEECCEEEC---------------CC---GGGCC-EECCEEEEEC
3704 T ss_pred EeCCceeEEEEEEecCCCcceeccccc-cccccceeEeeeeeec---------------CC---cccce-eEEEEEEEEc
3705 Confidence 9999 99999988776653 55566 7777777664554443 22 45566 7899999999
3706
3707
3708 Q sp|P0DTC2|SPIK 271 QPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSF 306 (1273)
3709 Q Consensus 271 qprtfllkynengtitdavdcaldplsetkctlksf 306 (1273)
3710 .+|+|||.||+||.|++||||+-|+++|-||..+|-
3711 T Consensus 302 ~~r~yLl~Fd~nG~It~AvDCa~d~~sELkCs~~~~ 337 (342)
3712 T 5X4R_A 302 QPLTFLLDFSVDGYIRRAIDCGFNDLSQLHCSYESH 337 (342)
3713 T ss_dssp EEEEEEEEECTTSCEEEEEEGGGCHHHHHHHC----
3714 T ss_pred ceeeEEEeccCCCeEEEEEecCCCcchhhcceecCC
3715 Confidence 999999999999999999999999999999998875
3716
3717
3718 No 46
3719 >6J11_C Spike glycoprotein, VH of 7D10; MERS-CoV, Antibody, VIRAL PROTEIN; HET: MAN, NAG, BMA; 3.0A {Middle East respiratory syndrome-related coronavirus}
3720 Probab=99.70 E-value=2.8e-21 Score=203.44 Aligned_cols=262 Identities=21% Similarity=0.313 Sum_probs=192.3 Template_Neff=4.300
3721
3722 Q sp|P0DTC2|SPIK 14 QCVNL-TTRTQLPPAYT----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG--T-------KRF 79 (1273)
3723 Q Consensus 14 qcvnl-ttrtqlppayt----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng--t-------krf 79 (1273)
3724 .|... ....-+++.++ -+-.+|+||||..++++..+-.|++|.+.-++.+-.- ++|++. + -.+
3725 T Consensus 12 ~C~~~~~~~~~~~~~~~~~idvs~~~G~yYp~~rvysN~tlL~qglfp~~gs~~~~y~---~~~~~~~~~~~~~~~~~~y 88 (336)
3726 T 6J11_C 12 ACIEVDIQQTFFDKTWPRPIDVSKADGIIYPQGRTYSNITITYQGLFPYQGDHGDMYV---YSAGHATGTTPQKLFVANY 88 (336)
3727 T ss_dssp BCCCEEECGGGGCCCCCCCCCGGGTTTCBCCSSCCCCSEEEEEEEEECCTTCCCEEEC---CEECCBSSSCBCSEEECSC
3728 T ss_pred ceEEeccCccccCCCCCcceecccCceeEeeCCeeEeeeeeeeeccccCCCCcceEEE---EEecCCCCCCCcceeeecC
3729 Confidence 36664 23333444554 3446899999999999999999999999988877543 233332 2 356
3730
3731
3732 Q sp|P0DTC2|SPIK 80 DNPVLPFNDGVYFASTEKSNIIRG-----------------WIFGTTLDSKT---Q------SLLIVNNATNVVI----- 128 (1273)
3733 Q Consensus 80 dnpvlpfndgvyfasteksniirg-----------------wifgttldskt---q------sllivnnatnvvi----- 128 (1273)
3734 +.+..||+||+++...+++|.-.+ ++||+|.+... + +++|+++-++.++
3735 T Consensus 89 ~~~~~~F~dGifvkv~~~~n~t~~~~~~~~~~~~~~~~ypa~~fGstf~N~s~~~~~~~~~~tlvI~P~~~g~~~~~~~c 168 (336)
3736 T 6J11_C 89 SQDVKQFANGFVVRIGAAANSTGTVIISPSTSATIRKIYPAFMLGSSVGNFSDGKMGRFFNHTLVLLPDGCGTLLRAFYC 168 (336)
3737 T ss_dssp TTCCEECTTCEEEEESTTTTSEEECSSSTTCEEEEECCCCCEEEESCEEECTTSCEEEECSEEEEEEEETTTTEEEEEEE
3738 T ss_pred CCChhhccCeEEEEEeeeeccCCCeeecCccccchhhcccceEEecccccCCCCcceeecceEEEEecCCCCceeeeEee
3739 Confidence 788999999999999887776443 57999999777 6 8999999888765
3740
3741
3742 Q sp|P0DTC2|SPIK 129 --KVCEFQFCNDPFLGVYYHKNN---KSWMES---------EFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVF 194 (1273)
3743 Q Consensus 129 --kvcefqfcndpflgvyyhknn---kswmes---------efrvyssannctfeyvsqpflmdlegkqgnfknlrefvf 194 (1273)
3744 +.++..-|..|..-+++.-+. -+|+.+ +++.|..+.||+|.+.. .|-+|. +.+.|. |.|
3745 T Consensus 169 ~~~~rtit~C~~p~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~f~~~~nc~f~~~~-nft~d~--~~~wf~----~~F 241 (336)
3746 T 6J11_C 169 ILEPRSGNHCPAGNSYTSFATYHTPATDCSDGNYNRNASLNSFKEYFNLRNCTFMYTY-NITEDE--ILEWFG----ITQ 241 (336)
3747 T ss_dssp EEEECCSBTSTTSTTCCCCCEEECHHHHCSSSSCCTTHHHHHHHHHEEEEEEEEEEEE-ECCCCC--CCEEEE----EEE
3748 T ss_pred eeccCccccCCCCCeEeeeeecCCCCccCCCccccccccccchhhhcccCCcEEEEee-ecCcch--hhheEe----EEE
3749 Confidence 333344566666655542221 345444 67788999999998753 444443 333443 999
3750
3751
3752 Q sp|P0DTC2|SPIK 195 KNIDG-YFKIYSKHTPINL---VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYL 270 (1273)
3753 Q Consensus 195 knidg-yfkiyskhtpinl---vrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgyl 270 (1273)
3754 ++.|| .|-+|--++..+. ...+| |...|.+..-+|..++ ++ .+.|. ..++|||++|
3755 T Consensus 242 ~~~~G~~f~~Y~~d~~~~~~f~f~~~~-g~~~l~yy~vip~s~~---------------~~---~~~~~-~~~ayyV~~L 301 (336)
3756 T 6J11_C 242 TAQGVHLFSSRYVDLYGGNMFQFATLP-VYDTIKYYSIIPHSIR---------------SI---QSDRK-AWAAFYVYKL 301 (336)
3757 T ss_dssp ETTEEEEEESTTTCTTTCCBEEEEEEC-CCSCCCEEEECCEEEC---------------CC---STTCC-EECCEEEEEC
3758 T ss_pred EeCCeeEEEEEEEccCCCcceeccccc-ceeccceeEeeeeeec---------------CC---cccce-eEEEEEEEEc
3759 Confidence 99999 9999887766653 55566 7777777664554443 22 45566 7899999999
3760
3761
3762 Q sp|P0DTC2|SPIK 271 QPRTFLLKYNENGTITDAVDCALDPLSETKCTLKS 305 (1273)
3763 Q Consensus 271 qprtfllkynengtitdavdcaldplsetkctlks 305 (1273)
3764 .+|+|||.||+||.|++||||+-|+++|-||..+|
3765 T Consensus 302 ~~~~yLl~Fd~nG~It~AvDCa~d~~sELkCst~S 336 (336)
3766 T 6J11_C 302 QPLTFLLDFSVDGYIRRAIDCGFNDLSQLHCSYES 336 (336)
3767 T ss_dssp EEEEEEEEECSSSCEEEEEETTSSHHHHHHHHHCC
3768 T ss_pred ceeeEEEeccCCCeEEEEEecCCCcchhheeeecC
3769 Confidence 99999999999999999999999999999998764
3770
3771
3772 No 47
3773 >5GYQ_A Spike glycoprotein; bat coronavirus HKU9, putative receptor; HET: NAG; 2.1A {Bat coronavirus HKU9}
3774 Probab=99.70 E-value=4.2e-21 Score=188.88 Aligned_cols=108 Identities=29% Similarity=0.580 Sum_probs=104.5 Template_Neff=2.900
3775
3776 Q sp|P0DTC2|SPIK 332 ITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIA 411 (1273)
3777 Q Consensus 332 itnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqia 411 (1273)
3778 |...|+|.++++ .++.+++.|.|+.++||..|+++|++.....+|+||||||.||.+.||..|+.|.|.|..+..++++
3779 T Consensus 2 ~~~~C~~~~~l~-~~~PsP~nWeR~~fsNCnFN~S~Llslv~v~sf~C~gISPskLasmCfsSVTiD~FaIp~s~~~~Lq 80 (176)
3780 T 5GYQ_A 2 IQSYCTPPYSVL-QDPPQPVVWRRYMLYDCVFDFTVVVDSLPTHQLQCYGVSPRRLASMCYGSVTLDVMRINETHLNNLF 80 (176)
3781 T ss_dssp CCEECCCCHHHH-HSCCCGGGCEEEEECSEEECGGGGTTSSCEEEEEEESSCHHHHTTSCBSEEEEEEEEECHHHHHHHH
3782 T ss_pred CCCCCCCChHhc-CCCCCCceeEEEEEeccCCchHHHHhhceeeeeeeeCCCHHHHhhcccceeEEEEEEeChHHHHhhc
3783 Confidence 567899999999 9999999999999999999999999999999999999999999999999999999999999999999
3784
3785
3786 Q sp|P0DTC2|SPIK 412 PGQTGKIADYNYKLPDDFTGCVIAWNSNN 440 (1273)
3787 Q Consensus 412 pgqtgkiadynyklpddftgcviawnsnn 440 (1273)
3788 +|++|-|++||||+|+||+||+++|+-+.
3789 T Consensus 81 ~GssG~i~~yNYKlp~~f~gC~l~y~l~~ 109 (176)
3790 T 5GYQ_A 81 NRVPDTFSLYNYALPDNFYGCLHAFYLNS 109 (176)
3791 T ss_dssp HTCCCHHHHHTCCCCTTCCEEEEEEEEEE
3792 T ss_pred CCCCcHHHhccccCCCCCCceEEEEEcCC
3793 Confidence 99999999999999999999999997653
3794
3795
3796 No 48
3797 >5ZVK_A Human Coronavirus MERS HR1 motif; MERS, Spike protein, S2 domain; 3.31A {Middle East respiratory syndrome-related coronavirus}
3798 Probab=99.68 E-value=7.3e-21 Score=169.61 Aligned_cols=79 Identities=56% Similarity=0.816 Sum_probs=69.9 Template_Neff=3.000
3799
3800 Q sp|P0DTC2|SPIK 910 GVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVE 988 (1273)
3801 Q Consensus 910 gvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkve 988 (1273)
3802 |+|++||.||||+||+.||.|+|.|++.+.++++||.|+|||||++++||+.|+.||+.|||||||.++||.+|||++|
3803 T Consensus 2 glt~~VL~~NQk~iA~sFN~A~~~i~~~~~t~~~AL~kiQ~VVN~q~~aL~~L~~qL~~NFgAISssI~dIy~RLd~le 80 (80)
3804 T 5ZVK_A 2 GITQQVLSENQKLIANKFNQALGAMQTGFTTTNEAFRKVQDAVNNNAQALSKLASELSNTFGAISASIGDIIQRLDVLE 80 (80)
3805 T ss_dssp --CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC-------
3806 T ss_pred CcchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHhcC
3807 Confidence 7899999999999999999999999999999999999999999999999999999999999999999999999999986
3808
3809
3810 No 49
3811 >2BEZ_C E2 GLYCOPROTEIN; MEMBRANE FUSION, SEVERE ACUTE RESPIRATORY; 1.6A {SARS CORONAVIRUS} SCOP: h.3.3.1
3812 Probab=99.63 E-value=8.5e-20 Score=162.03 Aligned_cols=77 Identities=88% Similarity=1.101 Sum_probs=75.2 Template_Neff=3.000
3813
3814 Q sp|P0DTC2|SPIK 914 NVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAE 990 (1273)
3815 Q Consensus 914 nvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkveae 990 (1273)
3816 +||.||||+||+.||.|++.|+..++++++||.|+|||||++++||+.|+.||+.|||||||.++||.+|||++||.
3817 T Consensus 1 ~VL~~NQk~iA~sFN~A~~~i~~~~~t~s~AL~kiQ~VVN~q~~aL~~L~~qL~~nFgAISssI~dIy~RLd~leAd 77 (77)
3818 T 2BEZ_C 1 NVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAE 77 (77)
3819 T ss_dssp CCSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
3820 T ss_pred ChhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHhcC
3821 Confidence 58999999999999999999999999999999999999999999999999999999999999999999999999984
3822
3823
3824 No 50
3825 >6M1V_A spike protein; 2019-nCoV, spike protein, fusion core; 1.5A {Severe acute respiratory syndrome coronavirus 2}
3826 Probab=99.60 E-value=2.8e-19 Score=168.19 Aligned_cols=98 Identities=56% Similarity=0.575 Sum_probs=68.4 Template_Neff=3.400
3827
3828 Q sp|P0DTC2|SPIK 917 YENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRL 996 (1273)
3829 Q Consensus 917 yenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrl 996 (1273)
3830 .||||+||+.||.|+|.|++.++++++||.|+|||||++++||+.|+.||+.|||||||.+. |++||.+|+||+
3831 T Consensus 1 ~~NQk~lA~sFN~A~~~i~~~~~t~~~Al~kiQ~VVN~q~~aL~~L~~qL~~nf~aisssi~------~~lea~~q~drl 74 (119)
3832 T 6M1V_A 1 MENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLLVPRGSGGSGGS------GGLEVLFQGPDV 74 (119)
3833 T ss_dssp CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCC--------------------------
3834 T ss_pred ChHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhccCCCcchhh------hhHHHhhcCCCc
3835 Confidence 38999999999999999999999999999999999999999999999999999999999977 899999999999
3836
3837
3838 Q sp|P0DTC2|SPIK 997 ITGRLQSLQTYVTQQLIRAAEIRA 1020 (1273)
3839 Q Consensus 997 itgrlqslqtyvtqqliraaeira 1020 (1273)
3840 ++|||..+..++++-....++++.
3841 T Consensus 75 itgrLsaLNatvldL~~Ei~~Lqe 98 (119)
3842 T 6M1V_A 75 DLGDISGINASVVNIQKEIDRLNE 98 (119)
3843 T ss_dssp ----CTTCCCCCCCCHHHHHHHHH
3844 T ss_pred CCCChHHhhHHHHHHHHHHHHHHH
3845 Confidence 999999999999887666655543
3846
3847
3848 No 51
3849 >5ZUV_A Spike glycoprotein,EK1, Spike glycoprotein,inhibitor EK1; Human Coronavirus 229E, Spike protein; 2.21A {Human coronavirus 229E}
3850 Probab=99.56 E-value=1.2e-18 Score=166.05 Aligned_cols=83 Identities=47% Similarity=0.646 Sum_probs=77.2 Template_Neff=2.400
3851
3852 Q sp|P0DTC2|SPIK 914 NVLYENQKLIANQFNSAIGKIQDS--------------LSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLND 979 (1273)
3853 Q Consensus 914 nvlyenqklianqfnsaigkiqds--------------lsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlnd 979 (1273)
3854 +||.||||+||+.||.|||.|+.. ++++++||.|+|||||++++||+.|++||+.|||||||.++|
3855 T Consensus 2 dVLq~NQkiiA~SFN~AignI~~aF~~vn~ai~qts~~~~Tva~AL~KIQdVVN~qg~AL~~Lt~QL~nNFqAISSSIqD 81 (133)
3856 T 5ZUV_A 2 DVLQENQKILAASFNKAMTNIVDAFTGVNDAITQTSQALQTVATALNKIQDVVNQQGNSLNHLTSQLRQNFQAISSSIQA 81 (133)
3857 T ss_dssp --CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
3858 T ss_pred cHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
3859 Confidence 689999999999999999999966 566779999999999999999999999999999999999999
3860
3861
3862 Q sp|P0DTC2|SPIK 980 ILSRLDKVEAEVQIDRL 996 (1273)
3863 Q Consensus 980 ilsrldkveaevqidrl 996 (1273)
3864 |.+|||++||.++.++|
3865 T Consensus 82 IY~RLD~leAd~~~gsl 98 (133)
3866 T 5ZUV_A 82 IYDRLDTIQSGGRGGSL 98 (133)
3867 T ss_dssp HHHHHTCSSCCCCSCCC
3868 T ss_pred HHHHHHHHHhhhccCcc
3869 Confidence 99999999999998776
3870
3871
3872 No 52
3873 >5YL9_A Spike glycoprotein; Spike protein, 6-helical bundle, post-fusion; 1.861A {Human coronavirus 229E}
3874 Probab=99.49 E-value=1.1e-17 Score=151.89 Aligned_cols=74 Identities=51% Similarity=0.726 Sum_probs=70.0 Template_Neff=2.900
3875
3876 Q sp|P0DTC2|SPIK 914 NVLYENQKLIANQFNSAIGKIQDS--------------LSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLND 979 (1273)
3877 Q Consensus 914 nvlyenqklianqfnsaigkiqds--------------lsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlnd 979 (1273)
3878 +||.||||+||+.||.|||.|+.. ++++++||.|+|||||++++||+.|.+||+.|||||||.++|
3879 T Consensus 2 ~VLq~NQk~iA~sFN~Aigni~~af~~vn~ai~qts~~~~tva~AL~KiQ~VVN~q~~aL~~Lt~QL~~NF~AISsSI~d 81 (89)
3880 T 5YL9_A 2 DVLQENQKILAASFNKAMTNIVDAFTGVNDAITQTSQALQTVATALNKIQDVVNQQGNSLNHLTSQLRQNFQAISSSIQA 81 (89)
3881 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
3882 T ss_pred cHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
3883 Confidence 689999999999999999999977 556679999999999999999999999999999999999999
3884
3885
3886 Q sp|P0DTC2|SPIK 980 ILSRLDKV 987 (1273)
3887 Q Consensus 980 ilsrldkv 987 (1273)
3888 |.+|||++
3889 T Consensus 82 Iy~RLd~l 89 (89)
3890 T 5YL9_A 82 IYDRLDTI 89 (89)
3891 T ss_dssp HHHHHHHC
3892 T ss_pred HHHHHhcC
3893 Confidence 99999974
3894
3895
3896 No 53
3897 >1WDF_B E2 glycoprotein; MHV, coronavirus, heptad repeat, fusion; 2.5A {Murine hepatitis virus} SCOP: h.3.3.1
3898 Probab=99.16 E-value=2.7e-14 Score=131.27 Aligned_cols=62 Identities=60% Similarity=0.836 Sum_probs=58.6 Template_Neff=2.400
3899
3900 Q sp|P0DTC2|SPIK 919 NQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDI 980 (1273)
3901 Q Consensus 919 nqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndi 980 (1273)
3902 |||.||+.||.|||.||+.++++++||.|+|||||++++||+.|+.||+.|||||||++.|.
3903 T Consensus 1 NQkiLAnsFN~AignIq~af~tts~AL~KIQdVVN~qg~AL~~Lt~QL~~NFgAISSsi~d~ 62 (95)
3904 T 1WDF_B 1 NQKMIASAFNNALGAIQDGFDATNSALGKIQSVVNANAEALNNLLNQLSNRFGAISDLSLDF 62 (95)
3905 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCC--CCCCCG
3906 T ss_pred CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHchHHHHHHHH
3907 Confidence 79999999999999999999999999999999999999999999999999999999999875
3908
3909
3910 No 54
3911 >1ZVA_A E2 glycoprotein; SARS coronavirus, membrane fusion, S2; 1.5A {SARS coronavirus} SCOP: h.3.3.1
3912 Probab=99.05 E-value=1.7e-13 Score=121.91 Aligned_cols=58 Identities=66% Similarity=0.811 Sum_probs=47.6 Template_Neff=4.100
3913
3914 Q sp|P0DTC2|SPIK 1144 ELDSFKEELDKYFKNHTSPDVDLGD-----ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQ 1201 (1273)
3915 Q Consensus 1144 eldsfkeeldkyfknhtspdvdlgd-----isginasvvniqkeidrlnevaknlneslidlq 1201 (1273)
3916 .|..|++||+|+||+++|.-.|+.+ ++++|+++++++.||+||+||+|+||||+|||+
3917 T Consensus 15 ~L~~f~~eL~~~FkaiSSsi~di~~rl~grLs~lNa~vl~l~~Ei~~L~~vik~LN~S~IdLk 77 (77)
3918 T 1ZVA_A 15 ALNTLVKQLSSNFGAISSVLNDISGGRGGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQ 77 (77)
3919 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHTTSCCCCTTHHHHHHHHHHHHHHHHHHHHHHHHHHHC--
3920 T ss_pred HHHHHHHHHHHHhchhhhchhhhcCCCCCChhhhcHHHHHHHHHHHHHHHHHHHHHHhhhccC
3921 Confidence 4566777777777777776655554 999999999999999999999999999999985
3922
3923
3924 No 55
3925 >5ZHY_D Spike glycoprotein,Spike glycoprotein; membrane fusion, broad-spectrum inhibitor design; 2.441A {Human coronavirus 229E}
3926 Probab=98.79 E-value=7.4e-12 Score=121.97 Aligned_cols=59 Identities=47% Similarity=0.667 Sum_probs=37.2 Template_Neff=2.300
3927
3928 Q sp|P0DTC2|SPIK 918 ENQKLIANQFNSAIGKIQDS--------------LSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSV 976 (1273)
3929 Q Consensus 918 enqklianqfnsaigkiqds--------------lsstasalgklqdvvnqnaqalntlvkqlssnfgaissv 976 (1273)
3930 ||||+||+.||.|||.|+.. ++++|+||.|+|||||+.++||+.|.+||+.||||||+-
3931 T Consensus 1 ~NQkiLAnSFN~AignIt~aF~~Vn~Ai~qts~~~~Tva~AL~KIQdVVN~Qg~ALs~Lt~QL~nNFqAIS~~ 73 (148)
3932 T 5ZHY_D 1 ENQKILAASFNKAMTNIVDAFTGVNDAITQTSQALQTVATALNKIQDVVNQQGNSLNHLTSQLRQNFQLVPRG 73 (148)
3933 T ss_dssp -----CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCC--------------
3934 T ss_pred ChHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCcccc
3935 Confidence 69999999999999999966 555679999999999999999999999999999999974
3936
3937
3938 No 56
3939 >5XJK_A Spike protein S2; VIRAL PROTEIN; NMR {Human SARS coronavirus}
3940 Probab=98.74 E-value=1.4e-11 Score=106.98 Aligned_cols=62 Identities=85% Similarity=1.326 Sum_probs=57.8 Template_Neff=4.400
3941
3942 Q sp|P0DTC2|SPIK 777 NTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYG 838 (1273)
3943 Q Consensus 777 ntqevfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqyg 838 (1273)
3944 +..+++..+|+-+++|-+..|+||||+.+||.+++++.||+||||||+||.++|.||++.|.
3945 T Consensus 3 ~~~~~~s~~~~~~~l~~~~~~~~fN~s~lL~~~~~~~~RSaIEDLLF~KV~t~~~G~v~~Yk 64 (65)
3946 T 5XJK_A 3 NTREVFAQVKQMYKTPTLKYFGGFNFSQILPSPLKPTKRSFIEDLLFNKVTLADAGFMKQYG 64 (65)
3947 T ss_dssp TTGGGHHHHTTCCCCCCCSSSCCCCGGGSSCCCCCCCGGGGGGHHHHTTTSSTTHHHHHGGG
3948 T ss_pred cHHHHHHHHHHHhcCCcccccCCccccccCCCCCCCCCccHHHHHhccceeecCcchhhhhc
3949 Confidence 34678899999999999999999999999999999999999999999999999999998885
3950
3951
3952 No 57
3953 >1ZV8_K E2 glycoprotein; SARS coronavirus, membrane fusion, S2; 1.94A {SARS coronavirus} SCOP: h.3.3.1
3954 Probab=98.55 E-value=1.2e-10 Score=98.26 Aligned_cols=50 Identities=82% Similarity=0.987 Sum_probs=48.5 Template_Neff=3.100
3955
3956 Q sp|P0DTC2|SPIK 919 NQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSS 968 (1273)
3957 Q Consensus 919 nqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlss 968 (1273)
3958 |||+||+.||.||+.|++.++++++||.|+|||||++++||+.|..||+.
3959 T Consensus 1 NQk~iA~sFN~Ai~~i~~g~~t~~~AL~KiQ~VVN~q~~aL~~Lt~qL~~ 50 (50)
3960 T 1ZV8_K 1 NQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSS 50 (50)
3961 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
3962 T ss_pred CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhC
3963 Confidence 79999999999999999999999999999999999999999999999963
3964
3965
3966 No 58
3967 >2IEQ_B Spike glycoprotein; Human coronavirus membrane fusion; 1.747A {Human coronavirus}
3968 Probab=98.54 E-value=1.3e-10 Score=109.56 Aligned_cols=84 Identities=33% Similarity=0.293 Sum_probs=64.1 Template_Neff=3.500
3969
3970 Q sp|P0DTC2|SPIK 921 KLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISS-VLNDIL--------SRLDKVEAEV 991 (1273)
3971 Q Consensus 921 klianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaiss-vlndil--------srldkveaev 991 (1273)
3972 .+-.+.||.||+.||+.++++++||.|+|||||+.+++|+.|..||..||++|+. .+ ||. +|+|+.|++.
3973 T Consensus 7 t~a~~~fn~Ai~~i~~g~~tt~~AL~KIQ~VVN~q~~tL~~Ll~QL~nNF~Ais~~~l-difN~T~LNLT~Ei~~LE~ra 85 (109)
3974 T 2IEQ_B 7 VASFSSVNDAITQTAEAIHTVTIALNKIQDVVNQQGSALNHLTSQLRHNFQSGGRGSG-RGGNLTYLNLSSELKQLEAKT 85 (109)
3975 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC-----------------CCCCCCHHHHHHHHHHH
3976 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhcccCCCCccCC-cchHhhhcchhHHHHHHHHHH
3977 Confidence 3456899999999999999999999999999999999999999999999999999 67 999 9999999999
3978
3979
3980 Q sp|P0DTC2|SPIK 992 QIDRLITGRLQSLQ 1005 (1273)
3981 Q Consensus 992 qidrlitgrlqslq 1005 (1273)
3982 +-=+-++-.||.+-
3983 T Consensus 86 ~~L~~~~~eLq~~I 99 (109)
3984 T 2IEQ_B 86 ASLFQTTVELQGLI 99 (109)
3985 T ss_dssp HHHHHHHHHHHHHH
3986 T ss_pred HHHHHHHHHHHHHH
3987 Confidence 88888888877653
3988
3989
3990 No 59
3991 >2FXP_A Spike glycoprotein; Prefusion Intermediate, Trimer, Coiled-coil, VIRAL; NMR {SARS coronavirus} SCOP: h.3.3.1
3992 Probab=98.52 E-value=1.6e-10 Score=98.19 Aligned_cols=54 Identities=98% Similarity=1.317 Sum_probs=52.8 Template_Neff=4.100
3993
3994 Q sp|P0DTC2|SPIK 1158 NHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIK 1211 (1273)
3995 Q Consensus 1158 nhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqyik 1211 (1273)
3996 |||+|+.++.++..+|++++|++.||++|+++.|+||+++|||++|++||+|||
3997 T Consensus 2 n~t~~~~~~~~l~~~N~t~LnLt~Ei~~Lq~~I~~LN~s~IdLe~Ln~~etYiK 55 (55)
3998 T 2FXP_A 2 SHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIK 55 (55)
3999 T ss_dssp CSCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTTCCC
4000 T ss_pred CCCCCCCCCCccccccccccchHHHHHHHHHHHHHHhhcCCCHHHhccceeecC
4001 Confidence 799999999999999999999999999999999999999999999999999998
4002
4003
4004 No 60
4005 >1WDG_B E2 glycoprotein; MHV, coronavirus, heptad repeat, fusion; 2.06A {Murine hepatitis virus} SCOP: h.3.3.1
4006 Probab=98.49 E-value=2.2e-10 Score=106.06 Aligned_cols=54 Identities=57% Similarity=0.760 Sum_probs=48.6 Template_Neff=3.000
4007
4008 Q sp|P0DTC2|SPIK 919 NQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSS--NFGA 972 (1273)
4009 Q Consensus 919 nqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlss--nfga 972 (1273)
4010 |||+||+.||.|||.||+.++++++||.|+|||||++++||+.|..||+. |++.
4011 T Consensus 1 NQk~iA~sFN~Aigni~~~f~~~~~AL~kiQ~VVN~q~~aL~~LtNQLS~~pn~~~ 56 (94)
4012 T 1WDG_B 1 NQKMIASAFNNALGAIQDGFDATNSALGKIQSVVNANAEALNNLLNQLSLVPRGSG 56 (94)
4013 T ss_dssp -CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCCC------
4014 T ss_pred ChHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCCCC
4015 Confidence 79999999999999999999999999999999999999999999999998 7777
4016
4017
4018 No 61
4019 >2BEQ_D E2 GLYCOPROTEIN; VIRAL PROTEIN, COILED COIL, MEMBRANE; HET: ACE; 1.6A {N/A}
4020 Probab=98.41 E-value=5.2e-10 Score=93.68 Aligned_cols=47 Identities=98% Similarity=1.271 Sum_probs=44.9 Template_Neff=3.400
4021
4022 Q sp|P0DTC2|SPIK 1166 LGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKW 1212 (1273)
4023 Q Consensus 1166 lgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqyikw 1212 (1273)
4024 ++|++.+|++++|++.||++|+++.|+||+|+|||++|++||+||||
4025 T Consensus 2 ~~~l~~~N~t~LnLs~Ei~~Lq~~I~~LN~s~IdLe~Ln~~etYiKW 48 (48)
4026 T 2BEQ_D 2 LGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKX 48 (48)
4027 T ss_dssp CCSCTTCCCCCCCCHHHHHHHHHHHTTGGGGEECHHHHHHHHHHHC-
4028 T ss_pred CCCccccccccccHHHHHHHHHHHHHHHHhcCCCHHHhcccchhcCC
4029 Confidence 67889999999999999999999999999999999999999999999
4030
4031
4032 No 62
4033 >2BEQ_E E2 GLYCOPROTEIN; VIRAL PROTEIN, COILED COIL, MEMBRANE; HET: ACE; 1.6A {N/A}
4034 Probab=98.41 E-value=5.2e-10 Score=93.68 Aligned_cols=47 Identities=98% Similarity=1.271 Sum_probs=44.3 Template_Neff=3.400
4035
4036 Q sp|P0DTC2|SPIK 1166 LGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKW 1212 (1273)
4037 Q Consensus 1166 lgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqyikw 1212 (1273)
4038 ++|++.+|++++|++.||++|+++.|+||+|+|||++|++||+||||
4039 T Consensus 2 ~~~l~~~N~t~LnLs~Ei~~Lq~~I~~LN~s~IdLe~Ln~~etYiKW 48 (48)
4040 T 2BEQ_E 2 LGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKX 48 (48)
4041 T ss_dssp -CTTTTCCCCCCCCHHHHHHHHHHHHTGGGTEEEHHHHHHHHHHHC-
4042 T ss_pred CCCccccccccccHHHHHHHHHHHHHHHHhcCCCHHHhcccchhcCC
4043 Confidence 67889999999999999999999999999999999999999999999
4044
4045
4046 No 63
4047 >6LXT_F Spike protein S2; 2019-nCoV, HR1 and HR2 domain; HET: PG4; 2.9A {Severe acute respiratory syndrome coronavirus 2}
4048 Probab=97.71 E-value=1.4e-07 Score=91.83 Aligned_cols=45 Identities=98% Similarity=1.275 Sum_probs=36.7 Template_Neff=2.500
4049
4050 Q sp|P0DTC2|SPIK 1163 DVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYE 1207 (1273)
4051 Q Consensus 1163 dvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkye 1207 (1273)
4052 .+..|.++.+||.|...|.|+.+|||||||||||||||||||||.
4053 T Consensus 87 RLItGRLaaLna~v~q~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 131 (132)
4054 T 6LXT_F 87 DVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYG 131 (132)
4055 T ss_dssp ---CCCCTTCCCCCCCCHHHHHHHHHHHHHGGGGSCCCCC-----
4056 T ss_pred chhcccHHHHHHHHHHHHHHHHHHHHHHHHHhHHhchHHHhHhcC
4057 Confidence 467899999999999999999999999999999999999999994
4058
4059
4060 No 64
4061 >6LXT_C 2019-nCoV S2 subunit; 2019-nCoV, HR1 and HR2 domain; HET: PG4; 2.9A {COVID-19 virus}
4062 Probab=97.71 E-value=1.4e-07 Score=91.83 Aligned_cols=45 Identities=98% Similarity=1.275 Sum_probs=38.5 Template_Neff=2.500
4063
4064 Q sp|P0DTC2|SPIK 1163 DVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYE 1207 (1273)
4065 Q Consensus 1163 dvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkye 1207 (1273)
4066 .+..|.++.+||.|...|.|+.+|||||||||||||||||||||.
4067 T Consensus 87 RLItGRLaaLna~v~q~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 131 (132)
4068 T 6LXT_C 87 DVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYG 131 (132)
4069 T ss_dssp CCCCCCCTTCCCCCCCCHHHHHHHHHHHHHGGGGCCCCCC-----
4070 T ss_pred chhcccHHHHHHHHHHHHHHHHHHHHHHHHHhHHhchHHHhHhcC
4071 Confidence 467899999999999999999999999999999999999999994
4072
4073
4074 No 65
4075 >4MOD_B HR1 of S protein, LINKER; MERS-CoV, Viral envelope proteins, Spike; 1.901A {Human betacoronavirus 2c EMC/2012}
4076 Probab=97.52 E-value=4.8e-07 Score=88.04 Aligned_cols=64 Identities=33% Similarity=0.482 Sum_probs=36.9 Template_Neff=3.100
4077
4078 Q sp|P0DTC2|SPIK 1142 QPELDSFKEELDKYFKNHTSPDVDL--------------------GDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQ 1201 (1273)
4079 Q Consensus 1142 qpeldsfkeeldkyfknhtspdvdl--------------------gdisginasvvniqkeidrlnevaknlneslidlq 1201 (1273)
4080 ...|..|++||+++||+++|.-.|+ |.++.+|+++++++.|+.+|++|.|.||||.|||+
4081 T Consensus 40 ~~aL~~l~~EL~knFkAISSsI~dIy~rld~~~~~ad~qvdrLitgrL~~LNa~~~dl~~em~~l~~vvk~LNes~idlk 119 (129)
4082 T 4MOD_B 40 AQALSKLASELSNTFGAISASIGDILVPRGSGGSGGSGGLEVLFQGPLTQINTTLLDLTYEMLSLQQVVKALNESYIDLK 119 (129)
4083 T ss_dssp HHHHHHHHHC---------------------------------------CCCCCCCCCHHHHHHHHHHHHHHHTTCCC--
4084 T ss_pred HHHHHHHHHHHHHHhCcchhhHHHhhhccCCCCCCccccchhhcCCChHHHHHHHHHHHHHHHHHHHHHHHHHHHhhcHH
4085 Confidence 3568899999999999999987776 45777999999999999999999999999999999
4086
4087
4088 Q sp|P0DTC2|SPIK 1202 ELGK 1205 (1273)
4089 Q Consensus 1202 elgk 1205 (1273)
4090 ||-.
4091 T Consensus 120 el~~ 123 (129)
4092 T 4MOD_B 120 ELLE 123 (129)
4093 T ss_dssp ----
4094 T ss_pred HHHh
4095 Confidence 9854
4096
4097
4098 No 66
4099 >1ZVB_A E2 glycoprotein; SARS coronavirus, membrane fusion, S2; 1.7A {SARS coronavirus} SCOP: h.3.3.1
4100 Probab=97.29 E-value=1.9e-06 Score=69.03 Aligned_cols=34 Identities=100% Similarity=1.192 Sum_probs=32.0 Template_Neff=3.100
4101
4102 Q sp|P0DTC2|SPIK 958 ALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEV 991 (1273)
4103 Q Consensus 958 alntlvkqlssnfgaissvlndilsrldkveaev 991 (1273)
4104 ||+.|+.||+.|||||||.++||.+|||++||.+
4105 T Consensus 1 al~~L~~qL~nnF~aISssI~di~~RLD~leA~~ 34 (34)
4106 T 1ZVB_A 1 ALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEV 34 (34)
4107 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTC
4108 T ss_pred CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcC
4109 Confidence 5889999999999999999999999999999864
4110
4111
4112 No 67
4113 >1WDG_B E2 glycoprotein; MHV, coronavirus, heptad repeat, fusion; 2.06A {Murine hepatitis virus} SCOP: h.3.3.1
4114 Probab=97.10 E-value=5.1e-06 Score=77.92 Aligned_cols=47 Identities=30% Similarity=0.468 Sum_probs=29.3 Template_Neff=3.000
4115
4116 Q sp|P0DTC2|SPIK 1156 FKNHTSPDVDLGD----ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQE 1202 (1273)
4117 Q Consensus 1156 fknhtspdvdlgd----isginasvvniqkeidrlnevaknlneslidlqe 1202 (1273)
4118 .-++++...++++ +++||++.+++++|+++|+||.|.||||.|||+|
4119 T Consensus 44 LtNQLS~~pn~~~~~~~~~~iN~t~lDl~~Em~~lq~vvk~LNeS~IdLKe 94 (94)
4120 T 1WDG_B 44 LLNQLSLVPRGSGGSGGSGGLNVTLLDLTYEMNRIQDAIKKLNESYINLKE 94 (94)
4121 T ss_dssp HHTTCCC-------------------CCHHHHHHHHHHHHHHHTTCCCTTC
4122 T ss_pred HHHHHhcCCCCCCCCCCcccchhhhHHHHHHHHHHHHHHHHHHHHhhcccC
4123 Confidence 4577777777777 9999999999999999999999999999999986
4124
4125
4126 No 68
4127 >6M1V_A spike protein; 2019-nCoV, spike protein, fusion core; 1.5A {Severe acute respiratory syndrome coronavirus 2}
4128 Probab=96.99 E-value=8.6e-06 Score=78.78 Aligned_cols=49 Identities=86% Similarity=1.074 Sum_probs=35.8 Template_Neff=3.400
4129
4130 Q sp|P0DTC2|SPIK 1157 KNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGK 1205 (1273)
4131 Q Consensus 1157 knhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelgk 1205 (1273)
4132 .+-+.+..++|+++.+|+++++++.||++|+||.|+||||+|||+||..
4133 T Consensus 67 a~~q~drlitgrLsaLNatvldL~~Ei~~LqevIk~LN~S~IDLk~~~~ 115 (119)
4134 T 6M1V_A 67 VLFQGPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELHH 115 (119)
4135 T ss_dssp ------------CTTCCCCCCCCHHHHHHHHHHHHHGGGGSCCGGGSCC
4136 T ss_pred HhhcCCCcCCCChHHhhHHHHHHHHHHHHHHHHHHHHHHHcccHHHhhc
4137 Confidence 3456677888999999999999999999999999999999999999864
4138
4139
4140 No 69
4141 >2BEQ_C E2 GLYCOPROTEIN; VIRAL PROTEIN, COILED COIL, MEMBRANE; HET: ACE; 1.6A {N/A} SCOP: h.3.3.1
4142 Probab=96.96 E-value=9.9e-06 Score=66.07 Aligned_cols=36 Identities=81% Similarity=0.995 Sum_probs=34.2 Template_Neff=3.500
4143
4144 Q sp|P0DTC2|SPIK 932 GKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLS 967 (1273)
4145 Q Consensus 932 gkiqdslsstasalgklqdvvnqnaqalntlvkqls 967 (1273)
4146 +.||+.++++++||.|+|||||++++||+.|.+||+
4147 T Consensus 2 ~~iq~gf~tta~AL~KIQ~VVN~qg~aL~~Lt~QL~ 37 (38)
4148 T 2BEQ_C 2 SQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLS 37 (38)
4149 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
4150 T ss_pred CchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhC
4151 Confidence 568999999999999999999999999999999996
4152
4153
4154 No 70
4155 >5ZVM_c Human Coronavirus SARS HR1 motif; SARS, Spike protein, S2 domain; 3.3A {Human SARS coronavirus}
4156 Probab=96.74 E-value=2.6e-05 Score=65.26 Aligned_cols=41 Identities=39% Similarity=0.648 Sum_probs=38.1 Template_Neff=3.500
4157
4158 Q sp|P0DTC2|SPIK 1165 DLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGK 1205 (1273)
4159 Q Consensus 1165 dlgdisginasvvniqkeidrlnevaknlneslidlqelgk 1205 (1273)
4160 .++|+..+|++++|++.||++|+++.|+||+++|||++|++
4161 T Consensus 4 ~~~~l~~~N~t~LnLt~Ei~~Lq~~Ik~LN~s~IDLe~Lnr 44 (44)
4162 T 5ZVM_c 4 RGGSLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKELGG 44 (44)
4163 T ss_dssp HHHCCTTCCCCCCCCHHHHHHHHHHHHHHHTTCCCCCCCTT
4164 T ss_pred CCCChhhccccccchHHHHHHHHHHHHHHHhhcCCHHHhCC
4165 Confidence 46788899999999999999999999999999999999874
4166
4167
4168 No 71
4169 >5ZVM_b Human Coronavirus SARS HR1 motif; SARS, Spike protein, S2 domain; 3.3A {Human SARS coronavirus}
4170 Probab=96.74 E-value=2.6e-05 Score=65.26 Aligned_cols=41 Identities=39% Similarity=0.648 Sum_probs=38.1 Template_Neff=3.500
4171
4172 Q sp|P0DTC2|SPIK 1165 DLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGK 1205 (1273)
4173 Q Consensus 1165 dlgdisginasvvniqkeidrlnevaknlneslidlqelgk 1205 (1273)
4174 .++|+..+|++++|++.||++|+++.|+||+++|||++|++
4175 T Consensus 4 ~~~~l~~~N~t~LnLt~Ei~~Lq~~Ik~LN~s~IDLe~Lnr 44 (44)
4176 T 5ZVM_b 4 RGGSLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKELGG 44 (44)
4177 T ss_pred CCCChhhcccccccHHHHHHHHHHHHHHHHhhccChHHhcC
4178 Confidence 46788899999999999999999999999999999999874
4179
4180
4181 No 72
4182 >2BEZ_F E2 GLYCOPROTEIN; MEMBRANE FUSION, SEVERE ACUTE RESPIRATORY; 1.6A {SARS CORONAVIRUS}
4183 Probab=96.44 E-value=8.7e-05 Score=61.42 Aligned_cols=42 Identities=100% Similarity=1.270 Sum_probs=37.4 Template_Neff=4.100
4184
4185 Q sp|P0DTC2|SPIK 1160 TSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQ 1201 (1273)
4186 Q Consensus 1160 tspdvdlgdisginasvvniqkeidrlnevaknlneslidlq 1201 (1273)
4187 ||+..++.++..+|++++|++.||++|+++.|+||+++|||+
4188 T Consensus 1 ts~~p~~~~l~~~N~t~LnLt~Ei~~Lq~~I~~LN~slIdLe 42 (42)
4189 T 2BEZ_F 1 TSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQ 42 (42)
4190 T ss_dssp CCCCCCCCCCTTCCCCCCCCHHHHHHHHHHHHHTSTTSCCCC
4191 T ss_pred CCCCcCcccccccccccccHHHHHHHHHHHHHHHHhccccCC
4192 Confidence 455566666889999999999999999999999999999985
4193
4194
4195 No 73
4196 >6LVN_B 2019-nCoV S2 subunit; 2019-nCoV, HR2 domain, VIRUS, VIRAL; 2.47A {COVID-19 virus}
4197 Probab=96.21 E-value=0.00019 Score=58.12 Aligned_cols=35 Identities=100% Similarity=1.213 Sum_probs=32.6 Template_Neff=3.900
4198
4199 Q sp|P0DTC2|SPIK 1169 ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 1203 (1273)
4200 Q Consensus 1169 isginasvvniqkeidrlnevaknlneslidlqel 1203 (1273)
4201 +..+|++++|++.||++|+++.|+||+|+|||++|
4202 T Consensus 2 ~~~~N~t~Lnlt~Ei~~lq~~I~~LN~s~IdLe~L 36 (36)
4203 T 6LVN_B 2 ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 36 (36)
4204 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTC
4205 T ss_pred CcccccccccHHHHHHHHHHHHHHHHhhcCChhhC
4206 Confidence 45689999999999999999999999999999875
4207
4208
4209 No 74
4210 >1ZV8_B E2 glycoprotein; SARS coronavirus, membrane fusion, S2; 1.94A {SARS coronavirus}
4211 Probab=96.21 E-value=0.00019 Score=58.12 Aligned_cols=35 Identities=100% Similarity=1.213 Sum_probs=26.7 Template_Neff=3.900
4212
4213 Q sp|P0DTC2|SPIK 1169 ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 1203 (1273)
4214 Q Consensus 1169 isginasvvniqkeidrlnevaknlneslidlqel 1203 (1273)
4215 +..+|++++|++.||++|+++.|+||+|+|||++|
4216 T Consensus 2 ~~~~N~t~Lnlt~Ei~~lq~~I~~LN~s~IdLe~L 36 (36)
4217 T 1ZV8_B 2 ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 36 (36)
4218 T ss_dssp ---CCCCCCCCHHHHHHHHHHHHHGGGGCC-----
4219 T ss_pred CcccccccccHHHHHHHHHHHHHHHHhhcCChhhC
4220 Confidence 45689999999999999999999999999999875
4221
4222
4223 No 75
4224 >6LVN_A Spike protein S2; 2019-nCoV, HR2 domain, VIRUS, VIRAL; 2.47A {Severe acute respiratory syndrome coronavirus 2}
4225 Probab=96.21 E-value=0.00019 Score=58.12 Aligned_cols=35 Identities=100% Similarity=1.213 Sum_probs=32.0 Template_Neff=3.900
4226
4227 Q sp|P0DTC2|SPIK 1169 ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 1203 (1273)
4228 Q Consensus 1169 isginasvvniqkeidrlnevaknlneslidlqel 1203 (1273)
4229 +..+|++++|++.||++|+++.|+||+|+|||++|
4230 T Consensus 2 ~~~~N~t~Lnlt~Ei~~lq~~I~~LN~s~IdLe~L 36 (36)
4231 T 6LVN_A 2 ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 36 (36)
4232 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC-
4233 T ss_pred CcccccccccHHHHHHHHHHHHHHHHhhcCChhhC
4234 Confidence 45689999999999999999999999999999875
4235
4236
4237 No 76
4238 >5YL9_B Spike glycoprotein; Spike protein, 6-helical bundle, post-fusion; 1.861A {Human coronavirus 229E}
4239 Probab=91.73 E-value=0.063 Score=48.02 Aligned_cols=41 Identities=29% Similarity=0.567 Sum_probs=34.5 Template_Neff=3.600
4240
4241 Q sp|P0DTC2|SPIK 1158 NHTSPDVDLGDISGINASVVNIQKEIDR--------------LNEVAKNLNESLIDLQ 1201 (1273)
4242 Q Consensus 1158 nhtspdvdlgdisginasvvniqkeidr--------------lnevaknlneslidlq 1201 (1273)
4243 .|+.||.+ +...|+.+.|+..||++ |.++.++||.+++||+
4244 T Consensus 4 ~~t~pdl~---ld~yN~tiLNLt~EI~~Le~rs~~L~~~~~~Lq~~I~nLN~TlVDLE 58 (59)
4245 T 5YL9_B 4 RGGVPDLV---VEQYNQTILNLTSEISTLENKSAELNYTVQKLQTLIDNINSTLVDLK 58 (59)
4246 T ss_dssp -CCCCCCC---CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCCCCC
4247 T ss_pred CCCCCCcc---cccccceecccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhccccC
4248 Confidence 57888884 57789999999999999 7788888888888875
4249
4250
4251 No 77
4252 >5ZUV_A Spike glycoprotein,EK1, Spike glycoprotein,inhibitor EK1; Human Coronavirus 229E, Spike protein; 2.21A {Human coronavirus 229E}
4253 Probab=89.53 E-value=0.16 Score=51.20 Aligned_cols=44 Identities=36% Similarity=0.593 Sum_probs=41.1 Template_Neff=2.400
4254
4255 Q sp|P0DTC2|SPIK 1161 SPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELG 1204 (1273)
4256 Q Consensus 1161 spdvdlgdisginasvvniqkeidrlnevaknlneslidlqelg 1204 (1273)
4257 ..|+..|....||.....+.-|+.||.++.|+||||.|||.|+|
4258 T Consensus 90 eAd~~~gsl~~~n~t~ldl~yem~~~~~~~k~l~~syi~lke~g 133 (133)
4259 T 5ZUV_A 90 QSGGRGGSLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKELG 133 (133)
4260 T ss_dssp SCCCCSCCCCCCCCCCCCCHHHHHHHHHHHHHHTTCCCCHHHHC
4261 T ss_pred HhhhccCccccceeeeHHHHHHHHHHHHHHHHHHHhhcchHhhC
4262 Confidence 45788899999999999999999999999999999999999987
4263
4264
4265 No 78
4266 >6MAR_D Immunoglobulin G PGT151 Fab, Heavy; Fusion protein-Fab complex, MEMBRANE PROTEIN; HET: NAG, MAN, GAL, FUC, BMA;{Homo sapiens}
4267 Probab=71.20 E-value=3 Score=42.93 Aligned_cols=29 Identities=34% Similarity=0.603 Sum_probs=12.5 Template_Neff=7.100
4268
4269 Q sp|P0DTC2|SPIK 1199 DLQELGKYEQYIKW-PWYIWLGFIAGLIAI 1227 (1273)
4270 Q Consensus 1199 dlqelgkyeqyikw-pwyiwlgfiagliai 1227 (1273)
4271 |+++|.+.+....| +|-.|++.|..++.+
4272 T Consensus 154 ~l~~l~~~~~l~~wf~~~~wl~~iki~i~i 183 (220)
4273 T 6MAR_D 154 DLLALDKWASLWNWFDISNWLWYIKIFIMI 183 (220)
4274 T ss_pred HHHhhHHHHHHHHhcChHHHHHHHHHHHHH
4275 Confidence 44444444444333 334444444433333
4276
4277
4278 No 79
4279 >6DCQ_D Envelope glycoprotein gp160, Immunoglobulin G; HIV-1, Glycoprotein, Env, VIRAL PROTEIN; HET: NAG, GAL, BMA, FUC, MAN;{Human immunodeficiency virus 1}
4280 Probab=68.19 E-value=3.9 Score=45.14 Aligned_cols=49 Identities=29% Similarity=0.335 Sum_probs=25.2 Template_Neff=6.700
4281
4282 Q sp|P0DTC2|SPIK 1197 LIDLQELGKYEQYIKW-PWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLK 1245 (1273)
4283 Q Consensus 1197 lidlqelgkyeqyikw-pwyiwlgfiagliaivmvtimlccmtsccsclk 1245 (1273)
4284 ..|++++.+......| .+..|++.|-.+|.||+..|.|-|+..|.+|..
4285 T Consensus 146 ~~~l~~l~~w~~~~~wf~i~~wl~yiki~i~iv~gli~lri~~~~~~~~~ 195 (352)
4286 T 6DCQ_D 146 EKDLLALDKWTNLWNWFGISNWLWYIRIFIMIVGGLIGLRIIFAVLSVIN 195 (352)
4287 T ss_pred HHHHHHhHhhhhhHhhhCHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4288 Confidence 3455555555554333 334455554444555555555655555555543
4289
4290
4291 No 80
4292 >6NIJ_B PGT145 Fab heavy chain, PGT145; HIV-1, antibody, glycoprotein, IMMUNE SYSTEM; HET: NAG, BMA; 5.7A {Homo sapiens}
4293 Probab=68.17 E-value=3.9 Score=44.93 Aligned_cols=51 Identities=27% Similarity=0.312 Sum_probs=26.1 Template_Neff=6.800
4294
4295 Q sp|P0DTC2|SPIK 1197 LIDLQELGKYEQYIKW-PWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGC 1247 (1273)
4296 Q Consensus 1197 lidlqelgkyeqyikw-pwyiwlgfiagliaivmvtimlccmtsccsclkgc 1247 (1273)
4297 ..|++++.+......| .|..|++.|-.++.||+..|.|-|+..|.+|...+
4298 T Consensus 146 ~~~l~~l~~w~~~~~wf~i~~w~~yiki~i~iv~gli~lrii~~~~~~~~~~ 197 (345)
4299 T 6NIJ_B 146 EQELLELDKWASLWNWFDITKWLWYIKIFIMIVGGLIGLRIVFTVLSIVNRI 197 (345)
4300 T ss_pred HHHHHHHHHhhhHHhhcChhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4301 Confidence 3455555555554443 34445555544555555556666655555554443
4302
4303
4304 No 81
4305 >1WDF_B E2 glycoprotein; MHV, coronavirus, heptad repeat, fusion; 2.5A {Murine hepatitis virus} SCOP: h.3.3.1
4306 Probab=63.13 E-value=5.7 Score=39.08 Aligned_cols=56 Identities=27% Similarity=0.481 Sum_probs=44.4 Template_Neff=2.400
4307
4308 Q sp|P0DTC2|SPIK 1144 ELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQE 1202 (1273)
4309 Q Consensus 1144 eldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqe 1202 (1273)
4310 .|......|.+-|..-.|. +.|...||.....+--|+.|+..+.|.||||.|||.|
4311 T Consensus 40 AL~~Lt~QL~~NFgAISSs---i~d~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 95 (95)
4312 T 1WDF_B 40 ALNNLLNQLSNRFGAISDL---SLDFEKLNVTLLDLTYEMNRIQDAIKKLNESYINLKE 95 (95)
4313 T ss_dssp HHHHHHHHHHHHTCC--CC---CCCGGGCCCCCCCCHHHHHHHHHHHHHHHTTCCCTTC
4314 T ss_pred HHHHHHHHHHHhHchHHHH---HHHHHHHchHHHHHHHHHHHHHHHHHHHHHHhhcccC
4315 Confidence 4555666777777666553 5667788999999999999999999999999999975
4316
4317
4318 No 82
4319 >6GY6_C XaxA, XaxB; bacterial toxin, pore forming-toxins, TOXIN; 4.0A {Xenorhabdus nematophila ATCC 19061}
4320 Probab=57.97 E-value=8.2 Score=41.00 Aligned_cols=24 Identities=17% Similarity=0.426 Sum_probs=14.9 Template_Neff=9.300
4321
4322 Q sp|P0DTC2|SPIK 1172 INASVVNIQKEIDRLNEVAKNLNE 1195 (1273)
4323 Q Consensus 1172 inasvvniqkeidrlnevaknlne 1195 (1273)
4324 +++.+..++++|++|++-.+.++.
4325 T Consensus 232 l~~~i~~L~~~I~~l~~~I~~~~~ 255 (424)
4326 T 6GY6_C 232 LSTTIKDLQSKIDEKNKEIDQFQK 255 (424)
4327 T ss_pred chHHHHHHHHHHHHHHHHHHHHHH
4328 Confidence 355666777777777666555443
4329
4330
4331 No 83
4332 >6OJ7_A Fusion glycoprotein F0; Fusion protein, fusion inhibitor, six-helix; 1.45A {N/A}
4333 Probab=57.49 E-value=8.5 Score=34.15 Aligned_cols=29 Identities=17% Similarity=0.297 Sum_probs=22.5 Template_Neff=4.500
4334
4335 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
4336 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
4337 =|.|+.+++++++.++-|+.++||.+|.+
4338 T Consensus 17 TNeAV~~L~~g~~~l~~Av~~iQd~IN~~ 45 (53)
4339 T 6OJ7_A 17 TNKAVVSLSNGVSVLTSKVLDLKNYIDKQ 45 (53)
4340 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4341 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHhhh
4342 Confidence 36778888888888888888888877753
4343
4344
4345 No 84
4346 >1G2C_W TWO HEPTAD REPEATS OF HRSV; membrane fusion, pneumovirus, HRSV, Viral; 2.3A {Human respiratory syncytial virus} SCOP: h.3.2.1
4347 Probab=57.47 E-value=8.5 Score=34.10 Aligned_cols=29 Identities=17% Similarity=0.297 Sum_probs=22.4 Template_Neff=4.400
4348
4349 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
4350 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
4351 =|.|+.+++++++.++-|+.++||.+|.+
4352 T Consensus 17 TNeAV~~L~~g~~~~~~Av~~iQd~IN~~ 45 (52)
4353 T 1G2C_W 17 TNKAVVSLSNGVSVLTSKVLDLKNYIDKQ 45 (52)
4354 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHCCCCC
4355 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHhhh
4356 Confidence 46778888888888888888888877753
4357
4358
4359 No 85
4360 >6NYX_H Fusion glycoprotein F0; Fusion protein, fusion inhibitor, six-helix; HET: PEG, PG4; 1.85A {N/A}
4361 Probab=57.31 E-value=8.6 Score=34.12 Aligned_cols=29 Identities=31% Similarity=0.434 Sum_probs=23.7 Template_Neff=4.500
4362
4363 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
4364 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
4365 =|.|+.+++++++.++-|+.++||.+|.+
4366 T Consensus 17 TNeAV~~l~~g~~~~~~Av~~iQd~IN~~ 45 (53)
4367 T 6NYX_H 17 TNKAVQSVQSSIGNLIVAIKSVQDYVNKE 45 (53)
4368 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHh
4369 Confidence 47788888888888888888888888754
4370
4371
4372 No 86
4373 >6O40_A Fusion glycoprotein F0; Fusion protein, fusion inhibitor, six-helix; 1.2A {N/A}
4374 Probab=57.31 E-value=8.6 Score=34.12 Aligned_cols=29 Identities=31% Similarity=0.434 Sum_probs=23.7 Template_Neff=4.500
4375
4376 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
4377 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
4378 =|.|+.+++++++.++-|+.++||.+|.+
4379 T Consensus 17 TNeAV~~l~~g~~~~~~Av~~iQd~IN~~ 45 (53)
4380 T 6O40_A 17 TNKAVQSVQSSIGNLIVAIKSVQDYVNKE 45 (53)
4381 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
4382 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHh
4383 Confidence 47788888888888888888888888754
4384
4385
4386 No 87
4387 >6GY8_A XaxA; bacterial toxin, pore forming-toxins, TOXIN; 2.5A {Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6)}
4388 Probab=54.96 E-value=10 Score=39.70 Aligned_cols=22 Identities=18% Similarity=0.404 Sum_probs=13.4 Template_Neff=9.700
4389
4390 Q sp|P0DTC2|SPIK 1173 NASVVNIQKEIDRLNEVAKNLN 1194 (1273)
4391 Q Consensus 1173 nasvvniqkeidrlnevaknln 1194 (1273)
4392 ++.+..++++|++|++-.+.++
4393 T Consensus 233 ~~~i~~L~~~I~~l~~~I~~~~ 254 (408)
4394 T 6GY8_A 233 STTIKDLQSKIDEKNKEIDQFQ 254 (408)
4395 T ss_dssp HHHHHHHHHHHHHHHHHHHHHH
4396 T ss_pred hHHHHHHHHHHHHHHHHHHHHH
4397 Confidence 5556666777776666555443
4398
4399
4400 No 88
4401 >6PWU_E Envelope glycoprotein gp160, Antibody PG16; HIV-1, ENV, VIRAL PROTEIN; HET: NAG, MAN, BMA, FUC, GAL;{Human immunodeficiency virus 1}
4402 Probab=52.04 E-value=12 Score=46.57 Aligned_cols=53 Identities=26% Similarity=0.308 Sum_probs=30.8 Template_Neff=5.500
4403
4404 Q sp|P0DTC2|SPIK 1196 SLIDLQELGKYEQYIKW-PWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCC 1248 (1273)
4405 Q Consensus 1196 slidlqelgkyeqyikw-pwyiwlgfiagliaivmvtimlccmtsccsclkgcc 1248 (1273)
4406 ...||++|.+....-.| .|-.|++.|-.+|.|+...|.|-++..|+++...++
4407 T Consensus 651 nek~l~~Ld~w~~l~~Wf~it~Wl~yIKi~i~Iv~gliglrii~~v~~~v~~~r 704 (858)
4408 T 6PWU_E 651 NEQELLELDKWANLWNWFDISNWLWYIKIFIMIVGGLIGLRIVFAVLSVINRVR 704 (858)
4409 T ss_pred HHHHHHchHHHHHHHHhhcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
4410 Confidence 34566667666665444 344566666666666666666666666666554443
4411
4412
4413 No 89
4414 >3EUH_B Chromosome partition protein mukF, MukE; Chromosome condensation, condensin, non-SMC subunit; HET: GLY; 2.9A {Escherichia coli}
4415 Probab=52.03 E-value=12 Score=44.15 Aligned_cols=126 Identities=22% Similarity=0.336 Sum_probs=81.9 Template_Neff=3.500
4416
4417 Q sp|P0DTC2|SPIK 858 LTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLI--------ANQFNS 929 (1273)
4418 Q Consensus 858 ltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqkli--------anqfns 929 (1273)
4419 |+++-..+.+|+-.-..+| ..|.-...|--..-+-|.+ -.+--|.||-.+|.++-|.|..+ ...+.+
4420 T Consensus 125 LS~~l~~va~eL~~a~~aA-~e~~~e~~W~~~V~apLky----SV~ei~d~Id~~QR~mDeqq~~vk~eIa~LL~qDW~~ 199 (440)
4421 T 3EUH_B 125 LSMQLSIVAGELKRAADAA-EEGGDEFHWHRNVYAPLKY----SVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRA 199 (440)
4422 T ss_dssp HHHHHHHHHHHHHHHHHHH-HTCCCHHHHCCCCCHCCCC----CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGG
4423 T ss_pred HHHHHHHHHHHHHHHHHHH-HhcCCHHHHHhhccccccc----cHHHHHHhcchhHHHHHHHHHHHHHHHHHHHHHHHHH
4424 Confidence 3344444455554444444 3333455676665555544 44567899999999999988543 345667
4425
4426
4427 Q sp|P0DTC2|SPIK 930 AIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSS------NFGAISSVLNDILSRLDKVE 988 (1273)
4428 Q Consensus 930 aigkiqdslsstasalgklqdvvnqnaqalntlvkqlss------nfgaissvlndilsrldkve 988 (1273)
4429 ||..-+.-|+.|++.|..|||.+......|.++...+.+ ....+..++-++..+||.+.
4430 T Consensus 200 AI~~Ce~LL~eTs~tLrELqdtL~aagd~lq~~Ll~IQ~~~~~~~~l~~v~~~~~~Lq~kLDrI~ 264 (440)
4431 T 3EUH_B 200 AISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRII 264 (440)
4432 T ss_dssp GHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCSCGGGHHHHHHHHHHHHHHH
4433 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcCCcchHHHHHHHHHHHHHHHHHH
4434 Confidence 888999999999999999999999888777766655432 22224445555555555544
4435
4436
4437 No 90
4438 >3MAW_A Fusion glycoprotein F0; Fusion protein, class I, paramyxovirus; HET: NAG, NDG; 3.5A {Newcastle disease virus}
4439 Probab=50.68 E-value=13 Score=43.97 Aligned_cols=76 Identities=29% Similarity=0.351 Sum_probs=26.5 Template_Neff=4.900
4440
4441 Q sp|P0DTC2|SPIK 875 SALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
4442 Q Consensus 875 sallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnq 954 (1273)
4443 ..-++|.+..|-.+|.+.|.||--|..+.--.. -.++++ .-|.-...=|.|+.++++.++.++.|+.++||-+|.
4444 T Consensus 83 ~~Rf~G~iig~~ALGVAtaaqiTA~vAl~~a~~---na~~I~--~lk~si~~TN~AV~~l~~~~~~~~~Av~~lQd~IN~ 157 (483)
4445 T 3MAW_A 83 QGRFIGAIIGSVALGVATAAQITAASALIQANQ---NAANIL--RLKESITATNEAVHEVTDGLSQLAVAVGKMQQFVND 157 (483)
4446 T ss_dssp -------------------------------CC---THHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4447 T ss_pred cceeeeehHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4448 Confidence 345678888888888888888876544321100 001111 011112345778888888888888888888888875
4449
4450
4451 Q sp|P0DTC2|SPIK 955 N 955 (1273)
4452 Q Consensus 955 n 955 (1273)
4453 +
4454 T Consensus 158 ~ 158 (483)
4455 T 3MAW_A 158 Q 158 (483)
4456 T ss_dssp H
4457 T ss_pred h
4458 Confidence 4
4459
4460
4461 No 91
4462 >6EK7_A YaxA; pathogens, pore forming toxins, alpha-helical; HET: MPD; 1.8A {Yersinia enterocolitica}
4463 Probab=49.86 E-value=14 Score=39.26 Aligned_cols=23 Identities=13% Similarity=0.316 Sum_probs=12.9 Template_Neff=9.300
4464
4465 Q sp|P0DTC2|SPIK 1172 INASVVNIQKEIDRLNEVAKNLN 1194 (1273)
4466 Q Consensus 1172 inasvvniqkeidrlnevaknln 1194 (1273)
4467 .+..+..++++|++|++-.+.++
4468 T Consensus 234 ~~~~i~~L~~~I~~l~~~I~~~~ 256 (410)
4469 T 6EK7_A 234 MRKSIKELDEKIKEKRQRIEQLK 256 (410)
4470 T ss_dssp CHHHHHHHHHHHHHHHHHHHHTH
4471 T ss_pred chHHHHHHHHHHHHHHHHHHHHH
4472 Confidence 34455666666666665544443
4473
4474
4475 No 92
4476 >1SVF_C SV5 FUSION PROTEIN; PARAMYXOVIRUS, FUSION, SV5, COILED-COIL, Viral; 1.4A {Simian virus 5 (strain W3)} SCOP: h.3.2.1
4477 Probab=49.38 E-value=14 Score=34.05 Aligned_cols=29 Identities=24% Similarity=0.340 Sum_probs=21.7 Template_Neff=4.200
4478
4479 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
4480 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
4481 =|.|+.+++++++.++.|+.++||.+|.+
4482 T Consensus 26 TNeAV~~l~~g~~~~~~Av~~iQd~IN~~ 54 (64)
4483 T 1SVF_C 26 TNAAVADVVQATQSLGTAVQAVQDHINSV 54 (64)
4484 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
4485 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHh
4486 Confidence 46677777888888888888888877653
4487
4488
4489 No 93
4490 >1SVF_A SV5 FUSION PROTEIN; PARAMYXOVIRUS, FUSION, SV5, COILED-COIL, Viral; 1.4A {Simian virus 5 (strain W3)} SCOP: h.3.2.1
4491 Probab=49.38 E-value=14 Score=34.05 Aligned_cols=29 Identities=24% Similarity=0.340 Sum_probs=21.7 Template_Neff=4.200
4492
4493 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
4494 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
4495 =|.|+.+++++++.++.|+.++||.+|.+
4496 T Consensus 26 TNeAV~~l~~g~~~~~~Av~~iQd~IN~~ 54 (64)
4497 T 1SVF_A 26 TNAAVADVVQATQSLGTAVQAVQDHINSV 54 (64)
4498 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
4499 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHh
4500 Confidence 46677777888888888888888877653
4501
4502
4503 No 94
4504 >2FYZ_E Fusion glycoprotein F0; Mumps virus fusion protein core; 2.2A {Mumps virus}
4505 Probab=48.54 E-value=15 Score=33.83 Aligned_cols=29 Identities=24% Similarity=0.274 Sum_probs=22.0 Template_Neff=4.200
4506
4507 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
4508 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
4509 =|.|+.+++++++.++-|+.++||.+|.+
4510 T Consensus 29 TNeAV~~l~~g~~~~~~Av~~iQd~IN~~ 57 (63)
4511 T 2FYZ_E 29 TNRAVFEVKEGTQRLAIAVQAIQDHINTI 57 (63)
4512 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHTTT
4513 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHh
4514 Confidence 46777788888888888888888877753
4515
4516
4517 No 95
4518 >2B9B_B Parainfluenza Virus 5 F Protein; fusion protein, pre-fusion conformation, VIRAL; HET: NAG; 2.85A {Simian virus 5}
4519 Probab=48.31 E-value=15 Score=43.73 Aligned_cols=76 Identities=21% Similarity=0.253 Sum_probs=40.5 Template_Neff=4.600
4520
4521 Q sp|P0DTC2|SPIK 875 SALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
4522 Q Consensus 875 sallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnq 954 (1273)
4523 ..-++|.+..|-.+|.+.|.||--|..+.--.. -.++++ .-|.-...=|.|+.++++.++.++-|+.++||-+|.
4524 T Consensus 79 ~~Rf~G~iig~~ALGVATaAqiTA~vAL~~a~~---na~~I~--~lk~si~~TN~AV~~l~~~~~~~~~Av~~iQd~IN~ 153 (497)
4525 T 2B9B_B 79 RRRFAGVVIGLAALGVATAAQVTAAVALVKANE---NAAAIL--NLKNAIQKTNAAVADVVQATQSLGTAVQAVQDHINS 153 (497)
4526 T ss_dssp --CCCSCCCCGGGGCEEEHHHHHHHHHHHHHHH---HHHHHT--TSHHHHHHSCCSECEEE--------EECSSHHHHHH
4527 T ss_pred chhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4528 Confidence 445788888888999998888876554321100 001110 001112245778888899999999999999988875
4529
4530
4531 Q sp|P0DTC2|SPIK 955 N 955 (1273)
4532 Q Consensus 955 n 955 (1273)
4533 +
4534 T Consensus 154 ~ 154 (497)
4535 T 2B9B_B 154 V 154 (497)
4536 T ss_dssp H
4537 T ss_pred c
4538 Confidence 4
4539
4540
4541 No 96
4542 >5YZC_B glycoprotein F2, glycoprotein F1,measles virus; glycoprotein, viral protein, fusion protein; HET: NAG, 95C; 2.334A {Measles virus (strain Ichinose-B95a)}
4543 Probab=47.22 E-value=16 Score=42.71 Aligned_cols=73 Identities=23% Similarity=0.281 Sum_probs=47.9 Template_Neff=4.700
4544
4545 Q sp|P0DTC2|SPIK 878 LAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
4546 Q Consensus 878 lagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
4547 ++|.|..+..+|.+.|.||--|..+.--- --.++++ .-|.-...=|.|+.++++.++.++.|+.++||-+|.+
4548 T Consensus 1 ~~g~~ig~~algvataaqita~~al~~a~---~na~~i~--~lk~si~~tn~AV~~L~~g~~~~~~AV~~lQd~IN~~ 73 (419)
4549 T 5YZC_B 1 FAGVVLAGAALGVATAAQITAGIALHQSM---LNSQAID--NLRASLETTNQAIEAIRQAGQEMILAVQGVQDYINNE 73 (419)
4550 T ss_dssp --CEEECHHHHCCCCHHHHHHHHHHHHHS---CCHHHHH--HHHHHHHTCCCSEEEECCTTSCCEEEEETTHHHCCCC
4551 T ss_pred ChhHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
4552 Confidence 46778888889988888887655432110 0011111 1111223458899999999999999999999999854
4553
4554
4555 No 97
4556 >1T98_B Chromosome partition protein mukF; WINGED HELIX, HELIX-TURN HELIX, DOMAIN; HET: MSE; 2.9A {Escherichia coli} SCOP: a.47.6.1, a.4.5.65
4557 Probab=46.81 E-value=16 Score=41.26 Aligned_cols=104 Identities=23% Similarity=0.322 Sum_probs=67.4 Template_Neff=3.500
4558
4559 Q sp|P0DTC2|SPIK 858 LTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIAN--------QFNS 929 (1273)
4560 Q Consensus 858 ltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklian--------qfns 929 (1273)
4561 |+++-..+.+|+-.-..+|. .|.=-..|--..-|-|.+ -.+--|.||..+|-++-|.|..+.+ .+.+
4562 T Consensus 125 LS~ql~~va~eL~~a~~AA~-e~gde~~W~~~V~apLky----SV~eifd~Id~~QR~mDeqQ~~vk~eIA~LL~~DW~~ 199 (287)
4563 T 1T98_B 125 LSMQLSIVAGELKRAADAAE-EGGDEFHWHRNVYAPLKY----SVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRA 199 (287)
4564 T ss_dssp HHHHHHHHHHHHHHHHHHHH-SCCSHHHHCCCCCHCCCC----CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHTC-----
4565 T ss_pred HHHHHHHHHHHHHHHHHHHH-hcCCHHHHHhhccccccc----cHHHHHHhcchHHHHHHHHHHHHHHHHHHHHCccHHH
4566 Confidence 34444445555444434443 333345676665555544 3456789999999999999865443 3457
4567
4568
4569 Q sp|P0DTC2|SPIK 930 AIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQL 966 (1273)
4570 Q Consensus 930 aigkiqdslsstasalgklqdvvnqnaqalntlvkql 966 (1273)
4571 ||..-+.-|+.|++.|..|||........|.++...+
4572 T Consensus 200 AI~~Ce~LL~eTs~tLrELqdtL~aagd~lq~~Ll~I 236 (287)
4573 T 1T98_B 200 AISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRI 236 (287)
4574 T ss_dssp -CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4575 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4576 Confidence 8888899999999999999999887776666554443
4577
4578
4579 No 98
4580 >1T98_A Chromosome partition protein mukF; WINGED HELIX, HELIX-TURN HELIX, DOMAIN; 2.9A {Escherichia coli} SCOP: a.47.6.1, a.4.5.65
4581 Probab=46.81 E-value=16 Score=41.26 Aligned_cols=104 Identities=23% Similarity=0.322 Sum_probs=70.3 Template_Neff=3.500
4582
4583 Q sp|P0DTC2|SPIK 858 LTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIAN--------QFNS 929 (1273)
4584 Q Consensus 858 ltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklian--------qfns 929 (1273)
4585 |+++-..+.+|+-.-..+|. .|.=-..|--..-|-|.+ -.+--|.||..+|-++-|.|..+.+ .+.+
4586 T Consensus 125 LS~ql~~va~eL~~a~~AA~-e~gde~~W~~~V~apLky----SV~eifd~Id~~QR~mDeqQ~~vk~eIA~LL~~DW~~ 199 (287)
4587 T 1T98_A 125 LSMQLSIVAGELKRAADAAE-EGGDEFHWHRNVYAPLKY----SVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRA 199 (287)
4588 T ss_pred HHHHHHHHHHHHHHHHHHHH-hCCCHHHHHhhccccccc----cHHHHHHhcchhHHHHHHHHHHHHHHHHHHHcccHHH
4589 Confidence 34444445555444434443 333345676665555544 3456789999999999999865443 3457
4590
4591
4592 Q sp|P0DTC2|SPIK 930 AIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQL 966 (1273)
4593 Q Consensus 930 aigkiqdslsstasalgklqdvvnqnaqalntlvkql 966 (1273)
4594 ||..-+.-|+.|++.|..|||........|.++...+
4595 T Consensus 200 AI~~Ce~LL~eTs~tLrELqdtL~aagd~lq~~Ll~I 236 (287)
4596 T 1T98_A 200 AISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRI 236 (287)
4597 T ss_pred HHHHHHHHHHHHhhHHHHHHHHHHHhHHHHHHHHHHH
4598 Confidence 8888899999999999999999887776666554443
4599
4600
4601 No 99
4602 >1G5G_F FUSION PROTEIN; fusion protein, NDV, Newcastle disease; HET: BMA, NAG; 3.3A {Newcastle disease virus} SCOP: f.12.1.1, h.3.2.1
4603 Probab=45.56 E-value=18 Score=42.92 Aligned_cols=76 Identities=30% Similarity=0.372 Sum_probs=15.9 Template_Neff=4.900
4604
4605 Q sp|P0DTC2|SPIK 875 SALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
4606 Q Consensus 875 sallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnq 954 (1273)
4607 ..-++|.+..|-.+|.+.|.||--|..+.--.. -.++++ .-|.-...=|.|+.++++.++.++-|+.++||-+|.
4608 T Consensus 83 ~~Rf~G~iig~~ALGVAtaAqiTA~vAl~~a~~---na~~I~--~lk~si~~TN~AV~~l~~~~~~~~~Av~~iQd~IN~ 157 (481)
4609 T 1G5G_F 83 QGRLIGAIIGGVALGVATAAQITAASALIQANQ---NAANIL--RLKESIAATNEAVHEVTNGLSQLAVAVGKMQQFVND 157 (481)
4610 T ss_dssp --------------------------------------------------------------CHHHHHHHHHHHHHHHHH
4611 T ss_pred cceehhhHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4612 Confidence 345678888888889888888876544321100 001110 011112234778888888888888888888888875
4613
4614
4615 Q sp|P0DTC2|SPIK 955 N 955 (1273)
4616 Q Consensus 955 n 955 (1273)
4617 +
4618 T Consensus 158 ~ 158 (481)
4619 T 1G5G_F 158 Q 158 (481)
4620 T ss_dssp H
4621 T ss_pred h
4622 Confidence 4
4623
4624
4625 No 100
4626 >5EVM_F Fusion glycoprotein F0; fusion protein, Nipah, prefusion, paramyxovirus; HET: MAN, NAG, MLI, BMA; 3.367A {Nipah virus}
4627 Probab=45.38 E-value=18 Score=43.38 Aligned_cols=76 Identities=29% Similarity=0.344 Sum_probs=44.9 Template_Neff=4.700
4628
4629 Q sp|P0DTC2|SPIK 875 SALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
4630 Q Consensus 875 sallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnq 954 (1273)
4631 ..-++|.+..|-.+|.+.|.||--|..+.--.. -.+++. .-|.-...=|.|+.++++.++.++.|+.++||-+|.
4632 T Consensus 107 ~~RF~G~vig~vaLGVATaAqiTA~vAL~~a~~---na~~I~--~lk~si~~TN~AV~~l~~~~~~~~~Avq~iQd~IN~ 181 (529)
4633 T 5EVM_F 107 DVRLAGVIMAGVAIGIATAAQITAGVALYEAMK---NADNIN--KLKSSIESTNEAVVKLQETAEKTVYVLTALQDYINT 181 (529)
4634 T ss_dssp ------EEEEHHHHCSEEHHHHHHHHHHHHHHH---HHHHHH--TTHHHHHHCCSSEEECCCSSSSCCEEEETTHHHCCC
4635 T ss_pred ChhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4636 Confidence 345678888888899888888876554432110 001110 011112345788888888999999999999988876
4637
4638
4639 Q sp|P0DTC2|SPIK 955 N 955 (1273)
4640 Q Consensus 955 n 955 (1273)
4641 +
4642 T Consensus 182 ~ 182 (529)
4643 T 5EVM_F 182 N 182 (529)
4644 T ss_dssp C
4645 T ss_pred c
4646 Confidence 4
4647
4648
4649 No 101
4650 >6T3F_F Fusion glycoprotein F0, Fab66 light; Fusion Protein, Glycoprotein, Antibody, Fab; HET: NAG; 3.2A {Nipah virus}
4651 Probab=42.88 E-value=21 Score=42.66 Aligned_cols=76 Identities=29% Similarity=0.344 Sum_probs=49.9 Template_Neff=4.700
4652
4653 Q sp|P0DTC2|SPIK 875 SALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
4654 Q Consensus 875 sallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnq 954 (1273)
4655 ..-++|.+..|-.+|.+.|.||--|..+.--.. -.+++. .-|.-...=|.|+.++++.++.++.|+.++||-+|.
4656 T Consensus 85 ~~Rf~G~iig~~ALGVAtaAqiTAgvAL~~a~~---na~~I~--~lk~si~~TN~AV~~l~~g~~~~~~Avq~iQd~IN~ 159 (502)
4657 T 6T3F_F 85 DVRLAGVIMAGVAIGIATAAQITAGVALYEAMK---NADNIN--KLKSSIESTNEAVVKLQETAEKTVYVLTALQDYINT 159 (502)
4658 T ss_dssp CSSCCSCEECHHHHCSCCHHHHHHHHHHHHHHH---HHHHHH--TTHHHHHHCCSSEEEECSSSSSCEEEEETTHHHCCC
4659 T ss_pred ChhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4660 Confidence 445678888888888888888876544321100 011111 011112345889999999999999999999999886
4661
4662
4663 Q sp|P0DTC2|SPIK 955 N 955 (1273)
4664 Q Consensus 955 n 955 (1273)
4665 +
4666 T Consensus 160 ~ 160 (502)
4667 T 6T3F_F 160 N 160 (502)
4668 T ss_dssp C
4669 T ss_pred c
4670 Confidence 4
4671
4672
4673 No 102
4674 >3N27_B Fusion glycoprotein F0, linker, Fusion; Fusion protein, Chimera protein, fusion; HET: CIT, TBU; 1.8A {Hendravirus, Nipahvirus}
4675 Probab=42.74 E-value=21 Score=34.63 Aligned_cols=28 Identities=32% Similarity=0.335 Sum_probs=18.2 Template_Neff=2.800
4676
4677 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
4678 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnq 954 (1273)
4679 -|.|+.+++++++.++-|+.++||.+|.
4680 T Consensus 18 TNeAV~eL~~gl~q~avAIqaIQd~IN~ 45 (80)
4681 T 3N27_B 18 TNEAVVKLQETAEKTVYVLTALQDYSGG 45 (80)
4682 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHSSS
4683 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHhcC
4684 Confidence 3556666666666666666666666654
4685
4686
4687 No 103
4688 >1ZTM_C Fusion glycoprotein; fusion protein, 6-helix bundle,trimer, post-fusion; HET: NAG; 3.05A {Human parainfluenza virus 3}
4689 Probab=42.53 E-value=21 Score=42.44 Aligned_cols=75 Identities=20% Similarity=0.251 Sum_probs=29.7 Template_Neff=4.800
4690
4691 Q sp|P0DTC2|SPIK 876 ALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
4692 Q Consensus 876 allagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
4693 .-++|.|..|-.+|.+.|.||--|..+.-.- --.++++ .-|.-...=|.|+.++++.++.++.|+.++||-+|.+
4694 T Consensus 90 ~r~~g~iig~~algvataaqita~~al~~a~---~na~~i~--~lk~si~~tn~AV~~L~~g~~~~~~Avq~iQd~IN~~ 164 (490)
4695 T 1ZTM_C 90 KRFFGGVIGTIALGVATSAQITAAVALVEAK---QARSDIE--KLKEAIRDTNKAVQSVQSSIGNLIVAIKSVQDYVNKE 164 (490)
4696 T ss_dssp ----------------------------CCC---CCCSHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
4697 T ss_pred ccchhHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhc
4698 Confidence 3467778888888888888887654432110 0011111 1122223458899999999999999999999998864
4699
4700
4701 No 104
4702 >4GIP_D Fusion glycoprotein F2, Fusion glycoprotein; PIV5, viral fusion protein, membrane; HET: NAG; 2.0A {Simian virus 5}
4703 Probab=42.00 E-value=22 Score=41.54 Aligned_cols=72 Identities=22% Similarity=0.278 Sum_probs=47.3 Template_Neff=4.800
4704
4705 Q sp|P0DTC2|SPIK 878 LAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVL-YENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
4706 Q Consensus 878 lagtitsgwtfgagaalqipfamqmayrfngigvtqnvl-yenqklianqfnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
4707 ++|.+..|..+|.+.|.||--|..+.- ..||.- ...-|.-...=|.|+.++++.++.++.|+.++||-+|.+
4708 T Consensus 1 ~~g~~ig~~algvataaqita~~al~~------a~~na~~i~~lk~si~~tn~AV~~L~~g~~~~~~Av~~lQd~IN~~ 73 (409)
4709 T 4GIP_D 1 FAGVVIGLAALGVATAAQVTAAVALVK------ANENAAAILNLKNAIQKTNAAVADVVQATQSLGTAVQAVQDHINSV 73 (409)
4710 T ss_dssp CCSCEECGGGGCEEEHHHHHHHHHHHH------THHHHHHHHTTHHHHHHCCCSEEEEEETTEEEEEEECTTHHHHHHH
4711 T ss_pred CchHHHHHHHHHHHHHHHHHHHHHHHH------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHc
4712 Confidence 467888888899888888876554321 111110 000111223457889999999999999999999988754
4713
4714
4715 No 105
4716 >6H2E_Q AhlB; Tripartite pore-forming toxin, TOXIN; 2.35A {Aeromonas hydrophila}
4717 Probab=41.72 E-value=22 Score=35.49 Aligned_cols=23 Identities=22% Similarity=0.426 Sum_probs=11.9 Template_Neff=9.500
4718
4719 Q sp|P0DTC2|SPIK 1173 NASVVNIQKEIDRLNEVAKNLNE 1195 (1273)
4720 Q Consensus 1173 nasvvniqkeidrlnevaknlne 1195 (1273)
4721 +..+..++++|++|++-.+.++.
4722 T Consensus 128 ~~~i~~l~~~I~~l~~~i~~~~~ 150 (274)
4723 T 6H2E_Q 128 QATIAGLQSNLDGARQELDSLNK 150 (274)
4724 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHH
4725 T ss_pred HHHHHHHHHHHHHHHHHHHHHHH
4726 Confidence 34445555556555555544444
4727
4728
4729 No 106
4730 >5IJO_G Nuclear pore complex protein Nup155; Nuclear pore complex, Nucleocytoplasmic transport; 21.4A {Homo sapiens}
4731 Probab=40.35 E-value=24 Score=42.67 Aligned_cols=55 Identities=18% Similarity=0.345 Sum_probs=33.8 Template_Neff=5.300
4732
4733 Q sp|P0DTC2|SPIK 1133 VNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEV 1189 (1273)
4734 Q Consensus 1133 vnntvydplqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnev 1189 (1273)
4735 ..++-|+.|.+|+....|+||||+|....-.-++...+. ..+.+|+++|++|...
4736 T Consensus 239 sk~~K~~dLP~eIqk~VE~LdkfIK~QkqisdEIsr~Ss--~~l~kV~~DIe~L~q~ 293 (599)
4737 T 5IJO_G 239 SKALKDENLPPVICQDVENLQKFVKEQKQVQEEISRMSS--KAMLKVQEDIKALKQL 293 (599)
4738 T ss_dssp ---------CHHHHHHHHHHHHHHHHHHHHHHHHHHHCC--SHHHHHHHHHHHHHHH
4739 T ss_pred chhhhhccCCHHHHHHHHHHHHHHHHHHHHHHHHHhcCH--HHHHHHHHHHHHHHHH
4740 Confidence 346778888889988899999999988776666665553 3466777777766543
4741
4742
4743 No 107
4744 >1WP7_A fusion protein; Nipah Virus, Fusion Core, heptad; 2.2A {Nipah virus}
4745 Probab=40.33 E-value=24 Score=34.77 Aligned_cols=28 Identities=32% Similarity=0.322 Sum_probs=18.7 Template_Neff=2.700
4746
4747 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
4748 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnq 954 (1273)
4749 -|.|+.+++++++.++-|+.++||-+|.
4750 T Consensus 18 TNeAV~eL~~gl~qtavAIqaIQD~IN~ 45 (89)
4751 T 1WP7_A 18 TNEAVVKLQETAEKTVYVLTALQDYGGS 45 (89)
4752 T ss_dssp HHHHHHHHHHHHHHHHHHHHHCCC----
4753 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHccC
4754 Confidence 4677777888888888888888877763
4755
4756
4757 No 108
4758 >1WP8_C fusion; Hendra Virus, Fusion Core, heptad; 2.2A {Hendra virus}
4759 Probab=39.60 E-value=25 Score=34.65 Aligned_cols=28 Identities=32% Similarity=0.322 Sum_probs=18.4 Template_Neff=2.700
4760
4761 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
4762 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnq 954 (1273)
4763 -|.|+.+++++++.++-|+.++||-+|.
4764 T Consensus 18 TNeAV~eL~~gl~qtavAIqaIQD~IN~ 45 (89)
4765 T 1WP8_C 18 TNEAVVKLQETAEKTVYVLTALQDYGGS 45 (89)
4766 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHTC----
4767 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHccC
4768 Confidence 4667777777777777777777777763
4769
4770
4771 No 109
4772 >6R1J_J AhlB; Tripartite pore-forming toxin, TOXIN; 1.92A {Aeromonas hydrophila J-1}
4773 Probab=39.16 E-value=26 Score=34.77 Aligned_cols=24 Identities=21% Similarity=0.447 Sum_probs=12.5 Template_Neff=9.700
4774
4775 Q sp|P0DTC2|SPIK 1172 INASVVNIQKEIDRLNEVAKNLNE 1195 (1273)
4776 Q Consensus 1172 inasvvniqkeidrlnevaknlne 1195 (1273)
4777 ++..+..++++|+.|++-.+.++.
4778 T Consensus 127 ~~~~i~~l~~~I~~l~~~I~~~~~ 150 (272)
4779 T 6R1J_J 127 LQATIAGLQSNLDGARQELDSLNK 150 (272)
4780 T ss_pred chHhHHHHHHHHHHHHHHHHHHHH
4781 Confidence 344445555566655555554444
4782
4783
4784 No 110
4785 >6C14_A Protocadherin-15, LHFPL tetraspan subfamily member; PCDH15, LHFPL5, protocadherin, tip link;{Mus musculus}
4786 Probab=38.64 E-value=27 Score=35.39 Aligned_cols=26 Identities=35% Similarity=0.680 Sum_probs=13.7 Template_Neff=10.000
4787
4788 Q sp|P0DTC2|SPIK 1108 NFYEPQIITTDNT--FVSGNCDVVIGIV 1133 (1273)
4789 Q Consensus 1108 nfyepqiittdnt--fvsgncdvvigiv 1133 (1273)
4790 ..|+-.+..+|+. -.+..+.|.|-++
4791 T Consensus 82 ~~~~l~V~A~D~~~~~~~~~~~v~I~V~ 109 (337)
4792 T 6C14_A 82 SYFKFQVIATDDYGKGLSGKADVLVSVV 109 (337)
4793 T ss_dssp CCEEEEEEEEHHHHTSCEEEEEEEECEE
4794 T ss_pred CeEEEEEEEEcCCCCCCCeEEEEEEEEe
4795 Confidence 4556666667764 2334455555443
4796
4797
4798 No 111
4799 >5EJB_D Fusion glycoprotein F0; prefusion form, viral glycoprotein, ectodomain; HET: NAG, SO4; 3.2A {Hendra virus}
4800 Probab=38.02 E-value=28 Score=41.68 Aligned_cols=76 Identities=28% Similarity=0.344 Sum_probs=45.1 Template_Neff=4.700
4801
4802 Q sp|P0DTC2|SPIK 875 SALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
4803 Q Consensus 875 sallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnq 954 (1273)
4804 ..-++|.+..|..+|.+.|.||--|..+.--.. -.+++. .-|.-...=|.|+.++++.++.++.|+.++||-+|.
4805 T Consensus 82 ~~Rf~G~iig~~AlgVAtaaqita~vAl~~a~~---na~~i~--~lk~si~~tn~AV~~L~~g~~~~~~Avq~lQd~IN~ 156 (501)
4806 T 5EJB_D 82 DVKLAGVVMAGIAIGIATAAQITAGVALYEAMK---NADNIN--KLKSSIESTNEAVVKLQETAEKTVYVLTALQDYINT 156 (501)
4807 T ss_dssp -------CEEHHHHCSEEHHHHHHHHHHHHHHH---HHHHHH--TTHHHHHTCCSSEEEEECSSSCEEEEEETTHHHCCC
4808 T ss_pred CcchHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4809 Confidence 345678888888888888888765543321100 001111 011112345889999999999999999999999886
4810
4811
4812 Q sp|P0DTC2|SPIK 955 N 955 (1273)
4813 Q Consensus 955 n 955 (1273)
4814 +
4815 T Consensus 157 ~ 157 (501)
4816 T 5EJB_D 157 N 157 (501)
4817 T ss_dssp C
4818 T ss_pred c
4819 Confidence 4
4820
4821
4822 No 112
4823 >2M8R_A Syntaxin-1A; syntaxin, SNARE, Prefusion, membrane protein; NMR {Rattus norvegicus}
4824 Probab=36.65 E-value=30 Score=29.72 Aligned_cols=12 Identities=8% Similarity=0.033 Sum_probs=5.6 Template_Neff=9.700
4825
4826 Q sp|P0DTC2|SPIK 1211 KWPWYIWLGFIA 1222 (1273)
4827 Q Consensus 1211 kwpwyiwlgfia 1222 (1273)
4828 +|-|++.+++++
4829 T Consensus 84 ~~~~~~~~~~~~ 95 (109)
4830 T 2M8R_A 84 RKKIMIIICCVI 95 (109)
4831 T ss_dssp HHHHHHHHHHHH
4832 T ss_pred HHHHHHHHHHHH
4833 Confidence 355555444333
4834
4835
4836 No 113
4837 >3HD7_B Vesicle-associated membrane protein 2, Syntaxin-1A; MEMBRANE PROTEIN, COILED-COIL, 4-HELICAL BUNDLE; HET: SO4, GGG; 3.4A {Rattus norvegicus}
4838 Probab=36.65 E-value=30 Score=29.72 Aligned_cols=12 Identities=8% Similarity=0.033 Sum_probs=5.6 Template_Neff=9.700
4839
4840 Q sp|P0DTC2|SPIK 1211 KWPWYIWLGFIA 1222 (1273)
4841 Q Consensus 1211 kwpwyiwlgfia 1222 (1273)
4842 +|-|++.+++++
4843 T Consensus 84 ~~~~~~~~~~~~ 95 (109)
4844 T 3HD7_B 84 RKKIMIIICCVI 95 (109)
4845 T ss_dssp HHHHHHHHHHHH
4846 T ss_pred HHHHHHHHHHHH
4847 Confidence 355555444333
4848
4849
4850 No 114
4851 >5C3L_B Nucleoporin Nup54, MGC84997 protein, Nucleoporin; nucleoporin, heterotrimeric coiled coils, kink; 2.9A {Xenopus laevis}
4852 Probab=34.34 E-value=35 Score=32.07 Aligned_cols=57 Identities=16% Similarity=0.251 Sum_probs=31.9 Template_Neff=8.500
4853
4854 Q sp|P0DTC2|SPIK 1131 GIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEV 1189 (1273)
4855 Q Consensus 1131 givnntvydplqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnev 1189 (1273)
4856 ++--+|-|+.|.|++....++|+++++....-.-++...+- ..+..+..++++|..-
4857 T Consensus 6 ~~~~~tkf~dLp~~~q~~l~~ld~~I~~q~~~~~el~~~~~--~~~~~i~~di~~l~~~ 62 (142)
4858 T 5C3L_B 6 EDSKALKDENLPQLLCQDVENFQKFVKEQKQVQEEISRMSS--KAMLKVQEDIKALKQL 62 (142)
4859 T ss_dssp ------------CCSGGGGGGGTHHHHHHHHHHHHHHHCCS--HHHHHHHHHHHHHHHH
4860 T ss_pred ccccccccccCCHHHHHHHHHHHHHHHHHHHHHHHHHhhch--HHHHHHHHHHHHHHHH
4861 Confidence 34557889999999999999999999987766655555443 3566666666655443
4862
4863
4864 No 115
4865 >5G6U_A LANGERIN; CARBOHYDRATE BINDING PROTEIN, LANGERIN, CD207; HET: TRP, CL, YJM; 1.844A {HOMO SAPIENS}
4866 Probab=32.97 E-value=38 Score=33.48 Aligned_cols=42 Identities=17% Similarity=0.467 Sum_probs=25.7 Template_Neff=9.700
4867
4868 Q sp|P0DTC2|SPIK 1038 KRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFP 1090 (1273)
4869 Q Consensus 1038 krvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfp 1090 (1273)
4870 .....|..||.... |..| |+....++|..|-..|.+-.+|..
4871 T Consensus 123 ~~~~~c~~~w~~~~-------~~cy----~~~~~~~tw~~A~~~C~~~g~~L~ 164 (261)
4872 T 5G6U_A 123 DILQVVSQGWKYFK-------GNFY----YFSLIPKTWYSAEQFCVSRNSHLT 164 (261)
4873 T ss_pred cccccCCCCeEEEC-------CEEE----EEEeceeCHHHHHHHHHHcCCEee
4874 Confidence 44567877776531 2211 222346788899999988766654
4875
4876
4877 No 116
4878 >3IPD_E Vesicle-associated membrane protein 2, Syntaxin-1A; MEMBRANE PROTEIN, COILED COIL, 4-HELICAL; 4.8A {Rattus norvegicus}
4879 Probab=26.85 E-value=56 Score=28.69 Aligned_cols=9 Identities=33% Similarity=0.386 Sum_probs=3.8 Template_Neff=8.400
4880
4881 Q sp|P0DTC2|SPIK 1212 WPWYIWLGF 1220 (1273)
4882 Q Consensus 1212 wpwyiwlgf 1220 (1273)
4883 +-|++.+++
4884 T Consensus 68 ~k~~iii~~ 76 (91)
4885 T 3IPD_E 68 LKMMIILGV 76 (91)
4886 T ss_dssp HHHHHTTTT
4887 T ss_pred HHHHHHHHH
4888 Confidence 344444443
4889
4890
4891 No 117
4892 >3HD7_A Vesicle-associated membrane protein 2, Syntaxin-1A; MEMBRANE PROTEIN, COILED-COIL, 4-HELICAL BUNDLE; HET: SO4, GGG; 3.4A {Rattus norvegicus}
4893 Probab=26.85 E-value=56 Score=28.69 Aligned_cols=9 Identities=33% Similarity=0.386 Sum_probs=3.8 Template_Neff=8.400
4894
4895 Q sp|P0DTC2|SPIK 1212 WPWYIWLGF 1220 (1273)
4896 Q Consensus 1212 wpwyiwlgf 1220 (1273)
4897 +-|++.+++
4898 T Consensus 68 ~k~~iii~~ 76 (91)
4899 T 3HD7_A 68 LKMMIILGV 76 (91)
4900 T ss_dssp HHHHHHHHH
4901 T ss_pred HHHHHHHHH
4902 Confidence 344444443
4903
4904
4905 No 118
4906 >6BP2_B Envelope Glycoprotein GP1, Envelope Glycoprotein; Marburg, Ravn, Glycoprotein, Complex, VIRAL; HET: NAG, BMA, MAN; 3.172A {Marburg marburgvirus}
4907 Probab=24.89 E-value=64 Score=35.25 Aligned_cols=40 Identities=13% Similarity=0.088 Sum_probs=26.5 Template_Neff=4.200
4908
4909 Q sp|P0DTC2|SPIK 925 NQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVK 964 (1273)
4910 Q Consensus 925 nqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvk 964 (1273)
4911 .+....+....++++.....+..+..+|-||..||.-|.-
4912 T Consensus 122 ~~l~k~~N~Ts~ALs~L~~ql~SLr~vvLQNR~ALD~LLa 161 (202)
4913 T 6BP2_B 122 CRLRRLANQTAKSLELLLRVTTEERTFSLINRHAIDFLLT 161 (202)
4914 T ss_dssp HHHHHHHHHHHHHHHHHHHHCCCCSCCCHHHHHHHHHHHH
4915 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHhhchhHHhHHHH
4916 Confidence 3334444445555556666666678899999999987654
4917
4918
4919 No 119
4920 >6QD8_D Light chain, Virion spike glycoprotein,EBOV-GP1; Antibody, immune response, viral infection; HET: NAG, BMA;{Homo sapiens}
4921 Probab=23.45 E-value=72 Score=33.90 Aligned_cols=34 Identities=18% Similarity=0.191 Sum_probs=21.5 Template_Neff=4.700
4922
4923 Q sp|P0DTC2|SPIK 931 IGKIQDSLSSTASALGKLQDVVNQNAQALNTLVK 964 (1273)
4924 Q Consensus 931 igkiqdslsstasalgklqdvvnqnaqalntlvk 964 (1273)
4925 +....++++.....+..+..+|-||..||.-|.-
4926 T Consensus 61 ~N~T~~aL~~L~~ql~Slr~vvLQNR~ALD~Ll~ 94 (168)
4927 T 6QD8_D 61 ANETTQALQLFLRATTELRTFSILNRKAIDFLLQ 94 (168)
4928 T ss_dssp HHHHHHHHHHHHHHCCCSEECCHHHHHHHHHHHH
4929 T ss_pred HHHHHHHHHHHHHHHHHHHHHHhhchhHHHHHHH
4930 Confidence 3334444444445555567788999999887643
4931
4932
4933 No 120
4934 >4NJL_A S protein; six-helix-bundle, coronavirus, MERS-Cov, fusion inhibitor; HET: PGE; 2.3A {Middle East respiratory syndrome coronavirus}
4935 Probab=22.64 E-value=76 Score=33.23 Aligned_cols=27 Identities=52% Similarity=0.736 Sum_probs=14.8 Template_Neff=2.500
4936
4937 Q sp|P0DTC2|SPIK 1178 NIQKEIDRLNEVAKNLNESLIDLQELG 1204 (1273)
4938 Q Consensus 1178 niqkeidrlnevaknlneslidlqelg 1204 (1273)
4939 .+--|.-.+..+.|.+||+.|||.|||
4940 T Consensus 104 d~t~~~~s~~q~~~~~ne~~~~~~~~~ 130 (131)
4941 T 4NJL_A 104 DLTYEMLSLQQVVKALNESYIDLKELG 130 (131)
4942 T ss_dssp CCHHHHHHHHHHHHHHHTTCCCGGGSC
4943 T ss_pred HHHHHHhhHHHHHHHHHHhcccHHHhc
4944 Confidence 333333444555566666666666665
4945
4946
4947 No 121
4948 >4LWS_B Uncharacterized protein; ESX Secretion, Signal Sequence, Type; HET: ACT, GOL; 2.0A {Thermomonospora curvata}
4949 Probab=22.18 E-value=79 Score=26.31 Aligned_cols=32 Identities=9% Similarity=0.094 Sum_probs=19.5 Template_Neff=10.300
4950
4951 Q sp|P0DTC2|SPIK 955 NAQALNTLVKQLSSNFGAISSVLNDILSRLDK 986 (1273)
4952 Q Consensus 955 naqalntlvkqlssnfgaissvlndilsrldk 986 (1273)
4953 .++++..+.+++...+..+...|+++-..|..
4954 T Consensus 54 a~~~~~~~~~~~~~~~~~~~~~l~~~~~~l~~ 85 (103)
4955 T 4LWS_B 54 AQAAYWNYQKEWDAAAKDMQNVVAQLGVAIRE 85 (103)
4956 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4957 Confidence 45556666666666666666666666555544
4958
4959
4960 No 122
4961 >2NRJ_A Hbl B protein; Enterotoxin Hemolysis Transmembrane; 2.03A {Bacillus cereus} SCOP: h.4.4.2
4962 Probab=21.90 E-value=80 Score=32.38 Aligned_cols=15 Identities=20% Similarity=0.202 Sum_probs=6.3 Template_Neff=9.900
4963
4964 Q sp|P0DTC2|SPIK 1205 KYEQYIKWPWYIWLG 1219 (1273)
4965 Q Consensus 1205 kyeqyikwpwyiwlg 1219 (1273)
4966 +|+.++..-|++++|
4967 T Consensus 194 ~~~~~~~~~~~~~~g 208 (346)
4968 T 2NRJ_A 194 YYKQLESDGFNVMKG 208 (346)
4969 T ss_dssp GGGCCC--CCGGGTS
4970 T ss_pred HHHHHhhccchhchH
4971 Confidence 455554444544444
4972
4973
4974 No 123
4975 >2N2A_B Receptor tyrosine-protein kinase erbB-2; HER2, ErbB2, Tyrosine kinase, Activation; NMR {Homo sapiens}
4976 Probab=21.75 E-value=81 Score=26.93 Aligned_cols=23 Identities=22% Similarity=0.033 Sum_probs=13.7 Template_Neff=7.000
4977
4978 Q sp|P0DTC2|SPIK 1206 YEQYIKWPWYIWLGFIAGLIAIV 1228 (1273)
4979 Q Consensus 1206 yeqyikwpwyiwlgfiagliaiv 1228 (1273)
4980 |||-.+-...|+.|.++|+++++
4981 T Consensus 1 ~~~~~~~~~~I~~~Vvg~l~~~~ 23 (58)
4982 T 2N2A_B 1 AEQRASPLTSIISAVVGILLVVV 23 (58)
4983 T ss_dssp CCCCCCHHHHHHHHHHHHHHHHH
4984 T ss_pred CCcccCChHHHHHHHHHHHHHHH
4985 Confidence 34555545557777777776443
4986
4987
4988 No 124
4989 >6F5U_B Envelope glycoprotein,GP1, Envelope glycoprotein; EBOLA VIRUS, FILOVIRIDAE, ENVELOPE GLYCOPROTEIN; HET: NAG, GOL, CQN, DMS, BMA, MAN; 2.07A {Zaire ebolavirus (strain Mayinga-76)}
4990 Probab=21.41 E-value=83 Score=33.10 Aligned_cols=38 Identities=16% Similarity=0.183 Sum_probs=24.4 Template_Neff=5.300
4991
4992 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVK 964 (1273)
4993 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqnaqalntlvk 964 (1273)
4994 ....+....++++.....+..+..+|-||..||.-|.-
4995 T Consensus 57 l~~~~n~T~~al~~L~~~l~slr~vvLQNR~aLD~Ll~ 94 (168)
4996 T 6F5U_B 57 LRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQ 94 (168)
4997 T ss_dssp HHHHHHHHHHHHHHHHHHCCCSEECCHHHHHHHHHHHH
4998 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHhhchhHHHHHHH
4999 Confidence 33334444555555555556677889999999887653
5000
5001
5002 No 125
5003 >5F1B_B GP1, GP2, Niemann-Pick C1 protein; Ebola virus, glycoprotein, NPC1-C, VIRAL; HET: NAG; 2.3A {Zaire ebolavirus}
5004 Probab=21.40 E-value=84 Score=31.95 Aligned_cols=37 Identities=16% Similarity=0.180 Sum_probs=24.1 Template_Neff=5.300
5005
5006 Q sp|P0DTC2|SPIK 929 SAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQ 965 (1273)
5007 Q Consensus 929 saigkiqdslsstasalgklqdvvnqnaqalntlvkq 965 (1273)
5008 ..+....++++.....+..+..+|-||..||.-|.-+
5009 T Consensus 52 ~~~n~t~~al~~L~~~l~sl~~vvLQNR~aLD~Ll~~ 88 (130)
5010 T 5F1B_B 52 QLANETTQALQLFLRATTELRTFSILNRKAIDFLLQR 88 (130)
5011 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHhhhHHHHHHHHHh
5012 Confidence 3344445555555555666778889999998876543
5013
5014
5015 No 126
5016 >6HS4_B Envelope glycoprotein,Envelope glycoprotein,Envelope glycoprotein, Envelope; Ebola Glycoprotein, Structure-based In Silico; HET: BMA, GON, NAG, GOL, MAN; 2.05A {Zaire ebolavirus (strain Mayinga-76)}
5017 Probab=21.34 E-value=84 Score=33.08 Aligned_cols=40 Identities=15% Similarity=0.150 Sum_probs=25.9 Template_Neff=5.300
5018
5019 Q sp|P0DTC2|SPIK 925 NQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVK 964 (1273)
5020 Q Consensus 925 nqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvk 964 (1273)
5021 .+....+....++++.....+..+..+|-||..||.-|.-
5022 T Consensus 55 ~~l~~~~n~t~~al~~L~~~l~sl~~vvLQNR~aLD~Ll~ 94 (168)
5023 T 6HS4_B 55 CGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQ 94 (168)
5024 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHhhchhHHHHHHH
5025 Confidence 3333444445555555566666677889999999987653
5026
5027
5028 No 127
5029 >2KG7_A Uncharacterized protein esxG (PE family; Protein complex, UNKNOWN FUNCTION; NMR {Mycobacterium tuberculosis}
5030 Probab=21.11 E-value=85 Score=25.82 Aligned_cols=66 Identities=11% Similarity=0.201 Sum_probs=38.0 Template_Neff=10.300
5031
5032 Q sp|P0DTC2|SPIK 923 IANQFNSAIGKIQDSLSSTASALGKLQDVVN-QNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVE 988 (1273)
5033 Q Consensus 923 ianqfnsaigkiqdslsstasalgklqdvvn-qnaqalntlvkqlssnfgaissvlndilsrldkve 988 (1273)
5034 .++++.+..+.|++.++.....+..|...-. ..+.+......++...+..+...|+++-..|.+..
5035 T Consensus 14 ~a~~~~~~~~~l~~~~~~l~~~~~~l~~~W~G~a~~af~~~~~~~~~~~~~~~~~L~~~~~~l~~~~ 80 (97)
5036 T 2KG7_A 14 SQSAFAAKAGLMRHTIGQAEQAAMSAQAFHQGESSAAFQAAHARFVAAAAKVNTLLDVAQANLGEAA 80 (97)
5037 T ss_dssp TTCHHHHHHHHHHHHHHHHHHHHHHHGGGTCSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTC
5038 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHhhcchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
5039 Confidence 4555666666666666555555554432222 23445666666666666666666666666665543
5040
5041
5042 No 128
5043 >6W08_B NSP15 endoribnuclease; Tripartite pore forming toxin, Cytotoxin; HET: EDO; 1.75A {Vibrio cholerae O1 biovar El Tor str. N16961}
5044 Probab=20.88 E-value=87 Score=32.75 Aligned_cols=55 Identities=15% Similarity=0.317 Sum_probs=27.7 Template_Neff=9.500
5045
5046 Q sp|P0DTC2|SPIK 1139 DPLQPELDSFKEELDKYFKNHTSPDVDLGD--------ISGINASVVNIQKEIDRLNEVAKNL 1193 (1273)
5047 Q Consensus 1139 dplqpeldsfkeeldkyfknhtspdvdlgd--------isginasvvniqkeidrlnevaknl 1193 (1273)
5048 +.++.+++.|+..|..+...-..-.-++.. ..+.++.+..++++|++|++-.+.+
5049 T Consensus 122 ~~~~~~~~~~~~~l~~f~~~~~~~~~~l~~~~~~~~~~~~~~~~~i~~L~~~I~~l~~~i~~~ 184 (359)
5050 T 6W08_B 122 QSLTSNIKRYDEGLNAWARQVEDAHNTLQQTIAQIQQEEVSIQAEIIATNAQIDLMKQQIAAF 184 (359)
5051 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCGGGHHHHHHHHHHHHHHHHHHHHH
5052 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
5053 Confidence 456666667777666554442222222322 1334445556666666665544433
5054
5055
5056 No 129
5057 >3OGI_C Putative ESAT-6-like protein 6, Putative; Structural Genomics, PSI-2, Protein Structure; HET: MSE; 2.549A {Mycobacterium tuberculosis}
5058 Probab=20.43 E-value=90 Score=26.79 Aligned_cols=66 Identities=14% Similarity=0.137 Sum_probs=31.7 Template_Neff=9.500
5059
5060 Q sp|P0DTC2|SPIK 921 KLIANQFNSAIGKIQDSLSSTASALGKLQDV-VNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDK 986 (1273)
5061 Q Consensus 921 klianqfnsaigkiqdslsstasalgklqdv-vnqnaqalntlvkqlssnfgaissvlndilsrldk 986 (1273)
5062 .-.++.+....+.|++.++.....+..|.+. ....+++......++...+..+...|+++-..|+.
5063 T Consensus 11 ~~~a~~l~~~~~~l~~~~~~l~~~~~~l~~~W~G~a~~af~~~~~~~~~~~~~~~~~l~~~~~~l~~ 77 (101)
5064 T 3OGI_C 11 DAHGAMIRAQAGLLEAEHQAIVRDVLAAGDFWGGAGSVACQEFITQLGRNFQVIYEQANAHGQKVQA 77 (101)
5065 T ss_dssp --CHHHHHHHHHHHHHHHHHHHHHHHHTGGGTTCTTSHHHHHHHHHHHHHHHHHTTCC---------
5066 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
5067 Confidence 3455666666666666666555555555332 22345555566666666666666666666555544
5068
5069
5070 No 130
5071 >5HJ3_L Envelope glycoprotein, KZ52 Antibody Fragment; Ebola virus, EOV, Ebolavirus, GP; HET: MAN, NAG, BMA; 3.3A {Ebola virus sp.}
5072 Probab=20.10 E-value=93 Score=31.85 Aligned_cols=35 Identities=17% Similarity=0.174 Sum_probs=23.0 Template_Neff=5.300
5073
5074 Q sp|P0DTC2|SPIK 930 AIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVK 964 (1273)
5075 Q Consensus 930 aigkiqdslsstasalgklqdvvnqnaqalntlvk 964 (1273)
5076 .+....++++.....+..+..+|-||..||.-|.-
5077 T Consensus 60 ~~n~t~~al~~L~~~l~sl~~vvLQNR~aLD~Lla 94 (136)
5078 T 5HJ3_L 60 LANETTQALQLFLRATTELRTFSILNRKAIDFLLQ 94 (136)
5079 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHhhchHHHHHHHH
5080 Confidence 33444455555555566677888999999887653
5081
5082
5083 No 131
5084 >6RX1_A Syncytin-1; HUMAN PLACENTAL PROTEIN, MEMBRANE FUSION; 2.1A {Homo sapiens}
5085 Probab=20.03 E-value=93 Score=30.99 Aligned_cols=53 Identities=26% Similarity=0.386 Sum_probs=30.7 Template_Neff=5.000
5086
5087 Q sp|P0DTC2|SPIK 908 GIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVK 964 (1273)
5088 Q Consensus 908 gigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvk 964 (1273)
5089 |.|+++.-+. .+..+....+....++++.....+..+..+|-||..||.-|.-
5090 T Consensus 12 ~~~~~~~~l~----~L~~~l~~~~n~t~~al~~L~~~l~sl~~vvLQNR~aLD~Ll~ 64 (108)
5091 T 6RX1_A 12 FQSTSTQFYY----KLSQELNGDMERVADSLVTLQDQLNSLAAVVLQNRRALDLLTA 64 (108)
5092 T ss_dssp ------CHHH----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTG
5093 T ss_pred ccchhhHHHH----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhchhHHHHHHH
5094 Confidence 5555553222 2333444445556666777777777788899999999887653
5095
5096