| LASTZ is designed to preprocess one sequence or set of sequences (which we collectively call the TARGET) and then align several QUERY sequences to it. LASTZ_D is a non-integer (D stands for Double) version of LASTZ that can be used to estimate substitution matrix that will be used to score alignments. |
hg clone https://toolshed.g2.bx.psu.edu/repos/devteam/lastz