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1 <tool id="pubClonoComput" name="Public Clonotypes" version="1.0">
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0
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2 <description>Compute public clonotypes from multiple repertoires</description>
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3 <requirements>
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4 <requirement type="package" version="0.19">pandas</requirement>
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5 </requirements>
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6 <command interpreter="python">public_clonotype_computation.py "$clonotype" "$output_file" "$Th.thres"
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7 #for x in $clono_files
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8 "$x.clfile"
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9 "$x.clfile.name"
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10 #end for
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11 </command>
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12 <inputs>
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13 <param name="clonotype" type="select" label="Clonotype definition">
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14 <option value="CDR3">CDR3</option>
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15 <option value="VCDR3">V+CDR3</option>
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16 <option value="JCDR3">J+CDR3</option>
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17 </param>
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18 <conditional name="Th">
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19 <param name="thres_select" type="select" label="Remove Clonotypes With Reads Fewer Than Threshold?">
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20 <option value="y">Yes</option>
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21 <option value="n" selected="true">No</option>
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22 </param>
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23 <when value="y">
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24 <param name="thres" type="integer" size="4" value="1" min="1" label="Keep Clonotypes with Number of Reads more than" />
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25 </when>
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26 <when value="n">
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27 <param name="thres" type="hidden" value="null" />
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28 </when>
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29 </conditional>
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30 <repeat name="clono_files" title="Files to be append" min="2">
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31 <param name="clfile" type="data" label="Clonotype_File" format="tabular" />
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32 </repeat>
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33 </inputs>
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34 <outputs>
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35 <data format="tabular" name="output_file" label="publicClonotypes" />
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36 </outputs>
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37 <help>
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38 This tool extracts the public (i.e., shared in at least two datasets) clonotypes between 2 or more clonotype repertoires (1st output of the Clonotype Diversity & Expression tool) according to 3 of the 5 supported clonotype definitions.
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39 </help>
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40 </tool>
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